LOC120095870

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC120095870 0.49 0.14 0.0e+00 0.19 0.35 0.35 0.35 3.0e-10 1.1e-19 2.6e-19 2.6e-19
2 PL gene expression LOC120095870 0.35 0.13 0.0e+00 0.18 0.25 0.23 0.24 5.9e-19 1.5e-27 8.1e-25 9.3e-26
3 NAcc gene expression LOC120095870 0.15 0.08 5.0e-10 0.05 0.09 0.09 0.09 1.5e-06 2.7e-10 7.8e-11 1.4e-10
4 Brain gene expression LOC120095870 0.11 0.06 1.0e-08 0.09 0.09 0.09 0.09 1.5e-08 1.5e-08 8.5e-09 1.6e-08
5 Brain mRNA stability LOC120095870 0.06 0.04 2.3e-04 0.01 0.02 0.03 0.03 2.1e-02 2.7e-03 1.9e-03 1.4e-03
6 BLA mRNA stability LOC120095870 0.05 0.04 5.9e-03 0.01 0.03 0.01 0.01 9.7e-02 1.1e-02 5.1e-02 4.9e-02
7 OFC gene expression LOC120095870 0.16 0.11 2.5e-03 0.06 0.09 0.09 0.07 1.7e-02 3.7e-03 4.8e-03 7.8e-03
8 PL mRNA stability LOC120095870 0.04 0.03 1.2e-04 0.03 0.02 0.02 0.02 5.3e-04 1.7e-03 3.4e-03 3.9e-03
9 pVTA gene expression LOC120095870 0.09 0.07 8.6e-03 0 -0 -0 -0 3.4e-01 6.8e-01 6.1e-01 4.2e-01
10 OFC mRNA stability LOC120095870 0.14 0.09 1.4e-03 0.04 0.05 0 0.02 4.6e-02 2.2e-02 2.5e-01 1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.81.33.41.81.5-1.7-1.00.80.10.10.60.6-1.5
Area under the delay curve1.61.72.9-1.4-1.21.51.6-1.7-1.3-1.31.01.1-0.9
BMI with tail0.31.03.91.10.9-1.1-0.2-0.1-0.8-0.71.01.0-2.0
BMI without tail0.81.64.72.21.9-2.0-1.21.00.60.7-0.1-0.1-0.7
Body weight3.414.339.06.25.5-5.7-3.93.52.12.1-0.6-0.6-1.8
Weight adjusted by age0.70.81.91.41.0-1.1-0.90.81.00.9-0.6-0.70.5
Bone surface1.01.74.42.11.8-1.9-1.31.00.10.10.60.6-1.6
Bone volume0.61.13.81.20.9-1.1-0.50.2-0.6-0.61.11.1-2.0
Breakpoint value in progressive ratio session1.61.73.1-0.8-1.00.91.1-1.0-1.4-1.41.71.5-1.7
Number of licking bursts8.09.411.32.62.8-2.7-3.13.43.23.2-3.1-3.23.2
Context. condit. distance diff. score1.31.55.60.4-0.0-0.30.4-0.8-1.1-1.11.81.8-2.4
Locomotion velocity, session 10.40.40.8-0.7-0.90.90.7-0.7-0.6-0.60.50.5-0.3
Locomotion distance, session 10.50.61.3-1.1-1.01.11.1-1.0-0.5-0.50.20.20.1
Locomotion velocity, session 20.20.20.70.20.3-0.1-0.00.20.50.5-0.7-0.70.8
Locomotion distance, session 20.20.30.8-0.7-0.70.90.6-0.40.20.1-0.2-0.20.7
Locomotion velocity, session 30.50.61.5-0.2-0.40.30.7-0.8-0.8-0.81.01.0-1.2
Locomotion distance, session 30.10.10.1-0.2-0.30.30.2-0.3-0.2-0.20.30.3-0.3
Stereotopy head waving bouts, day 30.70.82.51.61.1-1.4-0.80.80.80.8-0.3-0.3-0.0
Stereotopy head waving duration, day 30.00.00.10.30.2-0.40.0-0.00.10.2-0.2-0.20.1
Locomotion velocity, session 70.10.20.4-0.5-0.50.50.6-0.6-0.3-0.30.10.1-0.0
Locomotion distance, session 70.20.20.4-0.5-0.50.50.5-0.6-0.4-0.40.50.5-0.4
Stereotopy head waving bouts, day 70.60.61.1-0.9-1.01.01.0-0.9-0.7-0.70.60.6-0.4
Stereotopy head waving duration, day 70.20.20.5-0.6-0.70.70.6-0.4-0.3-0.30.10.10.1
Locomotion velocity, session 80.00.10.10.30.4-0.4-0.1-0.00.20.2-0.2-0.20.0
Locomotion distance, session 80.20.31.00.40.3-0.50.1-0.3-0.3-0.30.60.6-1.0
Degree of sensitization distance0.10.10.3-0.5-0.20.30.1-0.20.00.1-0.3-0.30.5
Degree of sensitization stereotypy0.50.50.7-0.8-0.80.80.8-0.7-0.7-0.70.60.6-0.4
Conditioned locomotion0.50.61.0-0.6-0.50.60.8-0.5-0.9-0.90.90.9-1.0
Cocaine response after cond. corrected0.20.20.50.50.6-0.7-0.60.50.00.2-0.4-0.50.1
Cocaine response after cond. not corrected0.40.51.2-0.2-0.40.10.3-0.4-1.0-0.90.80.8-1.1
Cocaine response before conditioning3.74.56.7-1.5-2.01.71.9-1.9-2.1-2.22.52.6-2.5
Saline control response1.82.44.01.81.3-1.4-1.72.01.91.7-1.1-1.01.2
Bone: connectivity density1.52.46.22.52.2-2.3-1.71.60.70.70.20.2-1.1
Bone: cortical apparent density0.10.10.4-0.4-0.30.20.6-0.3-0.5-0.40.10.1-0.2
Bone: cortical area0.30.52.10.70.5-0.5-0.10.1-0.5-0.50.90.9-1.4
Bone: cortical porosity0.00.00.10.2-0.1-0.1-0.20.10.30.2-0.1-0.10.3
Bone: cortical porosity0.30.30.8-0.6-0.90.80.4-0.5-0.3-0.40.50.5-0.1
Bone: cortical thickness0.30.41.20.90.8-0.8-0.50.5-0.2-0.20.50.5-1.1
Bone: cortical thickness0.40.50.91.00.8-0.9-0.90.90.60.5-0.2-0.20.0
Bone: cortical tissue density0.10.10.4-0.4-0.30.20.6-0.3-0.4-0.30.10.1-0.1
Condit. Reinf. active minus inactive responses0.91.01.4-1.2-1.21.10.9-1.1-1.1-1.10.90.9-0.7
Condit. Reinf. active-inactive response ratio0.90.91.2-0.9-1.10.80.8-0.9-1.1-1.11.01.0-0.9
Condit. Reinf. active responses1.31.62.1-1.4-1.51.41.1-1.4-1.2-1.21.21.2-0.9
Condit. Reinf. inactive responses1.01.22.1-1.3-1.31.51.3-1.3-0.8-0.90.90.9-0.5
Incentive salience index mean1.82.22.7-1.6-1.61.61.3-1.5-1.5-1.51.41.4-1.2
Condit. Reinf. lever presses2.02.62.9-1.6-1.71.61.4-1.6-1.6-1.61.71.7-1.5
Condit. Reinf. active minus inactive responses0.30.30.80.70.7-0.7-0.90.70.40.4-0.1-0.1-0.1
Condit. Reinf. active-inactive response ratio0.20.30.70.40.4-0.4-0.80.80.50.5-0.3-0.30.4
Condit. Reinf. active responses0.30.31.30.1-0.0-0.1-0.1-0.0-0.4-0.50.90.9-1.1
Condit. Reinf. inactive responses0.50.71.5-0.3-0.50.30.5-0.6-0.8-0.81.21.1-1.2
Condit. Reinf. lever presses1.21.63.1-0.7-0.90.71.0-1.1-1.3-1.31.61.6-1.8
Condit. Reinf. lever reinforcers received0.20.31.0-0.1-0.20.10.0-0.1-0.5-0.60.90.9-1.0
Conditioned reinforcement - actives3.23.25.32.32.3-1.9-2.02.21.81.7-1.2-1.20.7
Conditioned reinforcement - inactives1.31.51.81.11.3-0.9-1.31.31.31.3-1.3-1.31.1
Conditioned locomotion0.40.51.21.11.0-0.6-0.70.90.60.50.10.1-0.4
Patch foraging indifference point 0 sec0.00.00.10.20.2-0.3-0.10.20.10.1-0.1-0.0-0.0
Patch foraging indifference point AUC0.50.61.20.81.0-0.9-1.01.10.70.7-0.3-0.40.3
Delay disc. indifference point, 0s delay0.10.10.20.30.3-0.30.2-0.4-0.3-0.2-0.30.1-0.3
Delay disc. indifference point, 16s delay0.30.30.8-0.7-0.30.70.8-0.9-0.5-0.50.40.3-0.3
Delay disc. indifference point, 2s delay5.25.86.9-2.4-2.52.42.5-2.6-2.6-2.52.02.3-2.0
Delay disc. indifference point, 24s delay0.10.10.4-0.6-0.20.50.5-0.4-0.1-0.1-0.2-0.30.3
Delay disc. indifference point, 4s delay2.93.14.1-1.7-1.71.81.9-2.0-1.9-1.81.41.6-1.5
Delay disc. indifference point, 8s delay1.21.21.9-1.2-1.11.31.4-1.4-0.9-0.91.00.8-0.6
Indifference point function ln k0.10.10.30.3-0.20.0-0.30.30.60.4-0.2-0.20.5
Indifference point function log k0.10.10.30.3-0.20.0-0.30.30.60.4-0.2-0.20.5
Patch foraging total patch changes 0 sec0.00.00.10.00.1-0.1-0.10.20.10.10.00.0-0.0
Patch foraging total patch changes 12 sec0.00.00.10.20.2-0.3-0.00.2-0.0-0.00.20.1-0.3
Patch foraging total patch changes 18 sec0.40.61.40.50.7-0.8-1.01.20.70.7-0.5-0.60.6
Patch foraging total patch changes 24 sec0.30.40.6-0.8-0.60.70.6-0.3-0.5-0.60.80.7-0.5
Patch foraging total patch changes 6 sec0.00.00.10.30.2-0.3-0.10.30.10.10.20.1-0.2
Patch foraging time to switch 0 sec0.50.71.4-1.1-0.80.61.2-1.2-1.1-0.90.00.2-0.3
Patch foraging water rate 0 sec0.91.42.81.61.2-1.1-1.61.71.41.2-0.3-0.40.3
Patch foraging water rate 12 sec0.10.10.3-0.1-0.40.50.1-0.00.1-0.00.50.5-0.2
Patch foraging water rate 18 sec0.81.12.0-1.0-1.41.41.1-1.1-0.6-0.71.01.0-0.5
Patch foraging water rate 24 sec0.20.30.70.90.3-0.3-0.70.60.80.60.20.10.0
Patch foraging water rate 6 sec0.50.71.7-0.4-0.80.80.5-0.6-0.6-0.81.31.2-1.1
Seeking ratio, delayed vs. immediate footshock0.91.03.1-0.30.2-0.2-0.80.90.80.9-1.4-1.41.8
Distance traveled before self-admin1.01.11.8-1.3-1.31.21.1-1.0-1.0-1.00.90.8-0.6
Distance traveled after self-admin0.10.10.2-0.4-0.10.40.2-0.2-0.3-0.30.30.4-0.3
Extensor digitorum longus weight0.62.35.42.31.8-1.9-1.31.00.10.01.21.2-2.3
Bone: elastic displacement0.30.30.80.90.7-0.7-0.30.40.70.6-0.4-0.40.3
Bone: elastic work0.91.13.41.81.5-1.5-0.91.10.90.8-0.2-0.2-0.4
Bone: endosteal estimation0.61.32.31.51.3-1.3-1.31.31.21.1-0.7-0.70.5
Bone: endosteal perimeter0.20.31.10.50.1-0.2-0.10.1-0.2-0.30.90.9-1.1
Epididymis fat weight1.33.14.9-1.2-1.31.31.8-1.6-1.9-1.92.12.0-2.2
Delta time in closed arm before/after self-admin0.10.10.30.0-0.1-0.0-0.40.50.20.10.20.20.0
Delta time in open arm before/after self-admin2.32.23.3-1.8-1.81.61.7-1.8-1.5-1.41.01.0-0.7
Diff in mean of infusions in LGA sessions0.80.91.6-0.6-0.90.80.9-0.7-0.9-0.91.31.2-1.1
Delay discount exponential model param2.32.53.61.71.5-1.8-1.81.91.51.5-1.3-1.31.1
Extinction: sum of active levers before priming2.01.92.6-1.6-1.41.41.5-1.5-1.5-1.51.21.2-1.1
Active lever presses in extinction session 60.10.10.5-0.00.20.00.2-0.2-0.4-0.40.50.3-0.7
Bone: final force1.42.34.32.11.9-2.0-1.81.81.31.3-0.8-0.80.3
Bone: final moment1.42.24.12.01.9-1.9-1.71.71.31.3-0.9-0.90.5
Food consumed during 24 hour testing period0.81.01.70.90.7-0.8-1.31.01.11.1-0.9-0.91.1
Glucose0.00.10.1-0.2-0.00.10.4-0.3-0.2-0.1-0.3-0.30.2
Heart weight0.30.51.10.00.30.3-0.40.81.00.9-0.7-0.61.1
Delay discount hyperbolic model param2.32.43.61.71.6-1.8-1.81.91.61.5-1.2-1.31.1
Intermittent access intake day 1-15 change2.52.53.51.81.9-1.4-1.71.71.61.6-1.4-1.41.1
Intermittent access intake escalation1.41.42.11.41.4-1.1-1.31.31.21.2-0.9-0.90.6
Intermittent access intake escalation 20.20.20.30.40.5-0.3-0.50.50.50.5-0.4-0.40.4
Intermitt. access day 1 inactive lever presses1.21.31.90.81.1-0.9-1.31.41.31.2-1.1-1.11.2
Intermitt. access day 15 inactive lever presses0.30.30.60.50.5-0.7-0.40.20.40.5-0.8-0.80.5
Intermitt. access escalation Index1.11.01.7-1.0-1.21.31.1-1.0-0.7-0.81.01.0-0.6
Intermittent access day 1 total infusions1.31.52.5-1.5-1.31.61.3-1.3-1.1-1.11.01.0-0.7
Intermittent access day 15 total infusions0.00.00.2-0.1-0.00.50.2-0.10.0-0.00.10.1-0.1
Intermittent access terminal intake (last 3 days)0.10.10.3-0.4-0.20.60.3-0.3-0.2-0.20.10.1-0.1
Intermittent access total infusions0.80.91.4-1.0-1.01.21.1-1.0-0.9-0.90.70.7-0.7
Intermittent access day 1 locomotion5.76.07.7-2.6-2.72.82.7-2.7-2.3-2.32.22.2-1.8
Intermittent access day 15 total locomotion1.92.13.5-1.3-1.51.91.5-1.4-1.1-1.21.61.6-1.3
Intermittent access total locomotion3.74.26.0-2.2-2.32.52.1-2.0-1.8-1.91.91.9-1.5
Intermittent access standard deviation1.21.31.81.21.3-1.2-1.21.41.01.0-1.1-1.10.8
Left kidney weight3.59.821.54.64.2-4.0-3.63.52.72.6-1.2-1.30.1
Right kidney weight3.18.719.74.43.9-4.0-3.23.12.52.4-1.3-1.30.2
Cocaine induced anxiety3.23.74.4-1.8-1.91.91.8-1.7-2.0-2.02.12.1-2.0
Post-drug Anxiety4.24.66.7-2.6-2.52.42.2-2.4-2.2-2.21.71.7-1.3
Baseline Anxiety0.60.61.5-1.2-0.90.71.0-1.2-0.7-0.5-0.2-0.20.4
Tail length2.26.717.74.23.6-3.7-2.72.52.12.0-0.8-0.8-0.4
Length with tail4.917.843.56.65.9-6.0-4.64.43.23.1-1.4-1.4-0.6
Length without tail1.94.111.33.43.0-3.1-2.01.90.90.90.0-0.0-1.5
Times rat made contact with spout0.91.11.61.20.8-1.1-1.21.11.21.1-0.7-0.70.9
Lifetime Intake0.40.40.7-0.8-0.60.80.8-0.8-0.7-0.60.40.4-0.4
Liver weight, left1.01.62.61.51.5-1.6-1.31.61.11.1-0.9-0.80.6
Liver weight, right0.71.23.01.71.5-1.5-1.31.40.60.50.20.3-0.8
Locomotor activity0.30.51.61.30.8-0.9-0.70.70.80.60.00.1-0.2
Locomotor testing distance0.40.71.61.30.8-1.1-0.80.81.00.8-0.4-0.30.3
Locomotor testing rearing0.00.00.20.1-0.4-0.00.1-0.10.0-0.00.20.20.0
Locomotion in novel chamber0.40.51.30.40.4-0.4-1.11.10.90.8-0.5-0.50.8
Locomotion in novel chamber post-restriction0.30.30.80.80.5-0.5-0.90.70.70.50.10.1-0.0
Fecal boli incidents, locomotor time 10.20.20.50.70.4-0.5-0.50.60.30.20.30.3-0.4
Change in fecal boli incidents, locomotor task0.20.20.70.10.3-0.3-0.0-0.10.30.4-0.8-0.80.8
Time >=10cm from walls, locomotor time 12.62.63.2-1.5-1.81.61.5-1.6-1.7-1.71.61.6-1.4
Bouts of movement, locomotor time 10.60.61.21.11.0-0.9-1.01.00.80.7-0.2-0.30.2
Total resting periods, locomotor time 10.40.40.91.00.8-0.7-0.90.90.60.6-0.0-0.10.0
Rest time, locomotor task time 10.10.20.60.80.4-0.6-0.10.10.10.00.40.2-0.5
Distance moved, locomotor task time 10.10.10.5-0.7-0.40.60.3-0.1-0.1-0.1-0.10.00.3
Vertical activity count, locomotor time 10.10.10.2-0.00.40.0-0.50.50.30.3-0.3-0.30.3
Time >=10cm from walls, locomotor time 21.21.32.7-0.2-0.60.41.0-1.2-1.2-1.21.51.4-1.7
Bouts of movement, locomotor time 20.20.30.90.40.1-0.10.0-0.2-0.2-0.30.90.6-0.9
Total resting periods, locomotor time 20.20.20.60.50.3-0.3-0.1-0.1-0.1-0.20.80.4-0.8
Rest time, locomotor task time 20.70.71.2-0.6-1.00.61.1-0.9-0.8-0.81.10.9-0.8
Distance moved, locomotor task time 21.82.13.01.11.4-1.1-1.21.41.51.5-1.7-1.61.6
Vertical activity count, locomotor time 23.53.85.72.02.4-1.9-2.02.02.02.0-1.9-1.71.5
Light reinforcement 10.71.32.3-1.5-1.21.31.3-1.4-1.2-1.10.70.9-0.6
Light reinforcement 20.30.41.10.00.4-0.2-0.40.30.60.6-1.0-0.91.0
Bone: marrow area0.61.42.41.51.3-1.3-1.41.41.21.2-0.7-0.70.6
Bone: maximum diameter0.20.41.31.10.8-0.8-0.60.40.10.10.40.4-0.8
Bone: maximum force0.71.32.91.71.5-1.5-1.31.40.80.8-0.2-0.2-0.2
Bone: maximum moment0.71.22.71.71.4-1.5-1.31.30.90.9-0.3-0.3-0.1
Mean time between licks in bursts0.50.81.7-1.3-1.21.31.2-0.7-0.7-0.70.40.40.0
Mean num. licks in bursts2.32.73.6-1.1-1.61.31.5-1.9-1.7-1.71.91.9-1.8
Cd content in liver0.30.40.9-1.0-0.80.90.4-0.00.30.2-0.2-0.21.0
Co content in liver1.41.72.31.10.9-1.0-1.51.41.51.4-1.3-1.31.5
Cu content in liver0.30.30.5-0.7-0.60.70.3-0.2-0.5-0.60.70.7-0.6
Fe content in liver1.92.36.1-0.4-0.70.70.9-1.0-1.5-1.62.22.2-2.5
K content in liver0.40.40.6-0.6-0.50.50.3-0.4-0.8-0.70.80.8-0.8
Mg content in liver0.20.20.40.40.5-0.4-0.60.60.30.3-0.2-0.20.1
Mn content in liver0.60.71.60.30.5-0.5-0.70.60.80.9-1.1-1.11.3
Na content in liver0.10.10.40.0-0.1-0.00.4-0.3-0.4-0.40.50.5-0.6
Rb content in liver2.73.35.3-2.3-2.02.11.7-1.8-1.9-1.91.51.5-1.3
Se content in liver3.74.59.1-1.2-1.41.11.6-1.8-2.4-2.42.62.6-3.0
Sr content in liver2.72.53.21.61.7-1.5-1.31.21.61.7-1.8-1.81.5
Zn content in liver2.22.44.11.92.0-2.0-1.81.61.31.3-1.1-1.10.5
Bone: minimum diameter0.00.10.30.20.1-0.2-0.40.50.30.3-0.2-0.20.3
Time in familiar zone, hab. session 10.20.20.30.40.1-0.4-0.30.30.30.4-0.5-0.50.6
Time in novel zone, hab. session 10.00.00.10.30.4-0.3-0.20.20.10.10.00.0-0.2
Total zone transitions, hab. session 11.01.43.0-1.7-1.31.61.2-1.1-1.1-1.10.80.8-0.5
Total locomotion distance, hab. session 11.92.73.4-1.9-1.41.71.7-1.7-1.8-1.71.41.4-1.5
Locomotion velocity, hab. session 12.53.65.3-2.3-1.82.22.1-2.0-2.0-1.91.51.5-1.4
Time in familiar zone, hab. session 20.00.00.10.0-0.0-0.10.0-0.3-0.3-0.20.10.1-0.3
Time in novel zone, hab. session 20.10.10.4-0.5-0.50.60.6-0.3-0.2-0.20.20.20.0
Total zone transitions, hab. session 20.71.01.20.80.9-0.7-0.91.01.11.1-1.1-1.11.1
Total locomotion distance, hab. session 20.00.00.1-0.3-0.10.40.2-0.1-0.00.0-0.1-0.10.2
Locomotion velocity, hab. session 20.00.10.2-0.20.10.20.00.10.20.2-0.3-0.30.4
Novel to familiar place preference ratio0.60.61.10.60.5-0.6-0.50.60.90.9-0.9-0.91.0
Novelty place preference0.40.41.00.30.2-0.3-0.30.30.70.7-0.8-0.81.0
Time in novel zone, NPP test0.40.40.80.40.3-0.5-0.30.40.70.7-0.8-0.80.9
Total zone transitions, NPP test0.00.00.0-0.1-0.10.20.00.10.0-0.00.10.1-0.1
Total locomotion distance, NPP test1.72.42.7-1.3-1.31.51.7-1.5-1.6-1.61.61.6-1.6
Locomotion velocity, NPP test1.31.82.2-1.2-1.21.41.4-1.3-1.3-1.31.51.5-1.4
Intraocular pressure0.30.41.40.40.2-0.3-0.20.1-0.3-0.40.90.9-1.2
Delta distance traveled before/after self-admin0.80.91.40.91.2-0.8-1.11.10.91.0-1.0-0.70.7
Delta ambulatory time before/after self-admin0.10.20.20.30.5-0.2-0.50.40.40.4-0.5-0.30.4
Parametrial fat weight1.12.23.01.31.6-1.6-1.41.21.31.4-1.7-1.71.3
Pavlov. Cond. lever latency2.12.64.52.12.0-1.9-1.71.81.61.6-1.2-1.20.8
Pavlov. Cond. magazine entry latency0.00.00.00.2-0.0-0.1-0.0-0.20.1-0.00.20.2-0.2
Pavlov. Cond. change in total contacts1.11.21.5-1.2-1.11.01.0-1.2-1.2-1.21.01.0-0.9
Pavlov. Cond. index score0.81.01.2-0.9-1.00.80.9-1.1-1.0-1.01.01.0-0.9
Pavlov. Cond. latency score1.11.41.6-1.2-1.31.11.1-1.3-1.2-1.21.21.2-1.0
Pavlov. Cond. lever contacts2.12.43.7-1.9-1.81.71.6-1.7-1.6-1.51.21.2-0.9
Pavlov. Cond. magazine entry number0.40.40.90.20.6-0.4-0.40.60.50.6-1.0-1.00.9
Pavlov. Cond. intertrial magazine entries0.30.30.8-0.8-0.70.90.7-0.6-0.0-0.1-0.1-0.10.5
Pavlov. Cond. lever-magazine prob. diff.0.70.81.2-0.8-0.90.70.9-1.1-0.9-1.01.01.0-0.9
Pavlov. Cond. response bias0.70.81.2-0.7-0.90.70.8-1.0-0.9-0.91.11.1-1.0
Pavlov. Cond. lever latency1.52.02.41.31.4-1.4-1.31.41.41.4-1.6-1.51.4
Pavlov. Cond. magazine entry latency2.73.13.9-2.0-1.91.91.7-1.9-1.8-1.81.51.6-1.3
Pavlov. Cond. change in total contacts0.60.81.3-0.9-0.91.10.9-0.8-0.8-0.90.90.9-0.8
Pavlov. Cond. index score2.32.93.7-1.9-1.81.91.6-1.7-1.7-1.71.71.7-1.4
Pavlov. Cond. latency score2.42.93.5-1.8-1.81.91.6-1.7-1.7-1.71.71.7-1.4
Pavlov. Cond. lever contacts2.73.74.3-1.7-1.81.81.8-2.0-2.0-2.02.12.1-2.0
Pavlov. Cond. magazine entry number2.02.43.71.91.8-1.9-1.51.61.51.5-1.3-1.31.0
Pavlov. Cond. intertrial magazine entries0.70.91.41.10.9-1.1-1.01.21.11.0-0.6-0.60.7
Pavlov. Cond. lever-magazine prob. diff.2.12.73.6-1.8-1.81.91.6-1.6-1.6-1.61.51.5-1.3
Pavlov. Cond. response bias4.05.55.8-2.3-2.32.42.2-2.3-2.4-2.42.42.4-2.2
Time in closed arm before self-admin1.51.72.91.51.7-1.3-1.21.11.41.4-1.2-1.20.8
Time in closed arm after self-admin0.70.71.40.80.8-0.6-1.11.21.00.9-0.5-0.40.5
Time in open arm before self-admin0.10.10.40.20.2-0.1-0.40.60.20.2-0.10.00.1
Time in open arm after self-admin0.30.30.6-0.4-0.60.40.8-0.7-0.7-0.60.50.4-0.5
Bone: periosteal estimation0.40.92.31.51.2-1.3-1.11.10.60.6-0.0-0.0-0.4
Bone: periosteal perimeter0.81.43.5-0.2-0.70.60.7-0.7-1.1-1.21.71.7-1.9
Bone: post-yield work0.50.61.6-0.4-0.40.30.4-0.4-0.8-0.91.11.1-1.3
Progressive ratio test 1 active lever presses0.80.81.30.91.1-0.7-1.11.10.80.9-0.8-0.80.6
Progressive ratio test 1 breakpoint1.11.21.81.01.3-0.9-1.31.31.01.0-1.1-1.10.7
Progressive ratio test 1 inactive lever presses1.41.52.21.21.3-1.0-1.41.51.41.3-1.1-1.11.0
Progressive ratio test 2 active lever presses0.30.40.80.70.9-0.2-0.70.80.70.6-0.4-0.40.2
Progressive ratio test 2 breakpoint0.20.30.50.40.7-0.1-0.60.70.60.6-0.4-0.40.3
Progressive ratio test 2 inactive lever presses1.11.32.31.51.2-0.8-1.21.31.41.3-0.6-0.60.6
Incentive Sensitization - Responses0.20.20.6-0.5-0.40.80.3-0.3-0.2-0.30.40.4-0.2
Incentive Sensitization - Breakpoint0.20.20.8-0.6-0.50.90.4-0.3-0.3-0.30.50.5-0.3
Sum of active levers in priming session hrs 5-61.61.62.6-1.1-0.70.81.5-1.6-1.6-1.41.01.0-1.4
Progressive ratio0.20.20.8-0.2-0.20.2-0.20.10.30.4-0.7-0.60.9
Food seeking constrained by brief footshock0.10.10.2-0.4-0.30.3-0.20.20.00.0-0.3-0.20.5
Seeking ratio, punishment vs. effort0.10.10.20.40.4-0.5-0.40.4-0.0-0.00.30.2-0.5
Retroperitoneal fat weight2.68.611.9-2.6-2.72.43.5-3.4-3.3-3.22.72.6-2.8
Reaction time number correct0.50.81.50.91.0-0.7-1.21.20.90.9-0.6-0.60.5
Reaction time mean minus median3.04.06.0-1.4-2.11.71.8-1.7-1.9-2.12.42.5-2.3
Reaction time mean minus median AUC2.22.94.3-1.5-2.11.91.7-1.6-1.4-1.61.81.8-1.3
Reaction time num false alarms1.31.72.4-1.2-1.61.61.4-1.1-1.1-1.21.41.3-1.1
Reaction time num false alarms AUC1.82.43.2-1.3-1.71.71.7-1.4-1.4-1.51.81.7-1.5
Reaction time trials correct on left0.50.81.50.91.0-0.7-1.21.20.90.9-0.6-0.60.5
Reaction time trials on left0.50.71.30.80.9-0.6-1.21.10.90.8-0.6-0.60.5
Reaction time mean1.72.43.9-1.9-2.01.91.9-1.8-1.5-1.40.81.0-0.6
Reaction time mean AUC2.22.94.6-2.0-2.12.02.1-2.0-1.6-1.61.01.2-0.7
Median of all reaction times1.52.03.8-1.9-1.81.81.9-1.8-1.2-1.10.30.5-0.0
Reaction time omissions2.02.74.5-1.6-2.11.82.1-2.0-1.4-1.51.31.4-0.9
Reaction time false alarm rate2.43.34.3-1.5-2.01.82.1-1.8-1.7-1.81.91.8-1.7
Reaction time premature initiation rate0.10.10.2-0.4-0.40.30.2-0.5-0.3-0.40.40.5-0.3
Reaction time premature initiations0.00.00.1-0.00.00.0-0.40.00.0-0.00.20.2-0.1
Std. dev. reaction times2.33.24.4-1.6-2.11.81.9-1.8-1.8-1.81.71.9-1.5
Reaction time trials completed0.50.71.30.80.9-0.6-1.21.10.90.8-0.6-0.60.5
Reaction time trials AUC0.20.30.70.50.6-0.3-0.90.80.60.6-0.3-0.30.3
Run reversals in cocaine runway, females0.30.30.4-0.6-0.40.60.6-0.5-0.6-0.50.30.4-0.4
Run reversals in cocaine runway, males0.40.30.90.20.1-0.1-0.40.70.80.7-0.5-0.60.9
Latency to leave start box in cocaine runway0.20.20.50.30.5-0.30.2-0.20.30.4-0.7-0.70.5
Latency to leave start box in cocaine runway, F1.41.52.71.31.6-1.4-0.70.81.01.2-1.5-1.50.9
Latency to leave start box in cocaine runway, M1.71.72.5-1.4-1.61.61.4-1.4-1.0-1.11.21.2-0.7
Std. dev. time between licks in bursts0.30.30.6-0.3-0.60.70.5-0.1-0.4-0.50.80.8-0.6
Total sessions with >9 infusions0.00.10.2-0.0-0.10.10.3-0.4-0.2-0.20.20.2-0.3
Short access day 1 total inactive lever presses0.60.71.10.70.5-0.6-0.80.81.00.9-0.9-0.91.1
Short access day 10 total inactive lever presses1.82.03.41.81.6-1.6-1.61.61.41.4-1.0-1.00.7
Short access day 1 total infusions0.20.20.6-0.5-0.30.20.6-0.7-0.4-0.2-0.3-0.30.2
Short access day 10 total infusions0.91.01.4-1.2-1.01.11.1-1.2-1.0-1.00.70.7-0.6
Short access total infusions0.10.10.2-0.20.1-0.00.2-0.4-0.3-0.1-0.5-0.50.2
Short access day 1 locomotion1.01.11.9-1.4-1.31.21.2-1.3-0.9-0.90.70.7-0.3
Short access day 10 total locomotion1.01.12.0-1.1-1.41.11.1-1.1-0.9-0.90.90.9-0.5
Short access total locomotion1.71.72.6-1.5-1.51.31.5-1.6-1.3-1.31.01.0-0.8
One hour access (0.3 mA shock)0.40.40.90.20.20.1-0.60.90.90.8-0.5-0.50.9
Compulsive drug intake0.60.61.8-1.4-1.00.90.9-0.9-0.3-0.3-0.2-0.20.8
One hour access (shock baseline)0.20.20.70.60.3-0.1-0.60.80.30.20.40.4-0.4
Social response proportion2.12.34.51.92.1-1.9-1.81.81.41.3-0.9-0.80.4
Social responses0.20.20.50.70.6-0.5-0.40.60.20.10.40.6-0.6
Social time0.50.72.0-1.4-1.21.20.8-0.6-0.5-0.50.00.20.4
Soleus weight0.20.72.60.80.6-0.5-0.40.2-0.4-0.51.11.1-1.6
Bone: stiffness0.10.10.30.40.2-0.3-0.40.50.0-0.00.40.4-0.5
Tibialis anterior weight0.82.97.12.72.1-2.3-1.61.20.20.11.11.1-2.3
Time to tail flick, vehicle, before self-admin0.30.31.0-0.8-0.30.50.8-1.0-0.5-0.40.0-0.0-0.1
Time to tail flick, vehicle, after self-admin0.20.20.6-0.8-0.50.70.4-0.5-0.4-0.40.30.3-0.2
Time to tail flick, test, before self-admin0.80.81.51.21.2-1.0-0.70.70.90.9-0.8-0.70.4
Time to tail flick, test, after self-admin0.10.10.3-0.00.5-0.20.3-0.5-0.4-0.3-0.1-0.0-0.4
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.6-0.70.60.3-0.2-0.4-0.40.40.4-0.2
Delta time to tail flick, test, before/after SA0.90.81.1-0.9-0.80.70.9-1.0-1.1-1.00.80.8-0.9
Tibia length4.412.519.04.34.4-4.3-4.13.83.23.2-2.8-2.71.7
Ambulatory time before self-admin2.82.93.5-1.7-1.81.71.6-1.5-1.7-1.71.91.8-1.5
Ambulatory time after self-admin0.80.81.2-0.8-0.70.90.8-0.9-0.9-0.91.01.1-1.0
Bone: tissue strength0.60.60.80.70.8-0.7-0.50.50.80.8-0.9-0.90.8
Total heroin consumption6.17.19.4-3.1-3.02.82.7-2.5-2.7-2.72.52.5-2.0
Bone: trabecular number0.91.43.82.01.7-1.9-1.21.00.30.30.30.3-1.1
Bone: trabecular spacing1.21.64.0-2.0-1.81.91.4-1.3-0.8-0.80.20.20.5
Bone: trabecular thickness0.91.13.91.20.8-1.0-0.30.1-0.5-0.51.21.2-2.0
Bone: trabecular tissue density1.21.72.0-1.1-1.21.21.4-1.1-1.3-1.31.41.4-1.4
Water consumed over 24 hours3.33.95.32.31.9-2.1-2.22.22.22.1-1.5-1.51.5
Number of responses in last shaping day0.10.10.20.30.1-0.2-0.30.30.40.4-0.3-0.30.4