Hub : Genes

LOC120095870

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120095870 0.09 0.06 8.7e-05 0.01 0.03 0.03 0.02 2.9e-02 1.1e-03 4.0e-03 9.3e-03
2 BLA gene expression LOC120095870 0.44 0.14 5.6e-17 0.16 0.32 0.33 0.33 4.7e-09 7.7e-18 4.6e-18 5.2e-18
3 NAcc gene expression LOC120095870 0.17 0.09 2.0e-10 0.05 0.07 0.07 0.08 4.6e-08 3.3e-11 1.9e-11 8.6e-12
4 IC gene expression LOC120095870 0.59 0.14 0.0e+00 0.21 0.36 0.38 0.38 3.2e-09 6.7e-16 6.6e-17 9.4e-17
5 PL gene expression LOC120095870 0.32 0.12 0.0e+00 0.18 0.24 0.23 0.24 1.6e-19 9.8e-26 2.5e-25 1.6e-25
6 Brain mRNA stability LOC120095870 0.05 0.03 8.4e-04 0.01 0.03 0.01 0.03 1.2e-02 1.7e-03 2.2e-02 2.0e-03
7 OFC mRNA stability LOC120095870 0.15 0.09 1.2e-03 0.07 0.06 0.02 0.03 9.9e-03 2.0e-02 1.3e-01 6.8e-02
8 Brain gene expression LOC120095870 0.1 0.06 1.5e-08 0.08 0.09 0.09 0.09 5.2e-08 5.0e-09 9.2e-09 7.3e-09
9 BLA mRNA stability LOC120095870 0.06 0.04 2.4e-03 0.02 0.03 0.03 0.01 2.9e-02 9.2e-03 1.3e-02 6.1e-02
10 OFC gene expression LOC120095870 0.12 0.09 9.1e-03 0.05 0.06 0.04 0.04 2.1e-02 1.4e-02 3.2e-02 3.7e-02
11 PL mRNA stability LOC120095870 0.03 0.02 8.3e-04 0.02 0.02 0.01 0.01 5.1e-03 6.3e-03 8.3e-03 3.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.01.89.01.41.31.61.30.90.7-3.00.6-0.2-0.6-0.9
Area under the delay curve1.11.32.0-1.3-1.4-1.1-1.2-1.1-1.3-0.3-1.2-1.2-1.1-1.0
BMI with tail0.41.55.01.21.32.11.31.00.4-2.20.4-0.5-0.8-0.8
BMI without tail1.34.19.72.42.53.12.32.01.6-2.91.50.60.1-0.1
Body weight4.720.741.55.85.66.45.34.94.1-5.73.92.00.90.3
Weight adjusted by age0.50.71.30.91.11.01.00.90.9-0.50.90.80.60.4
Bone surface1.32.38.11.71.72.11.71.30.9-2.90.80.0-0.4-0.7
Bone volume0.81.47.70.70.71.20.70.3-0.1-2.8-0.1-0.8-1.2-1.4
Breakpoint value in progressive ratio session0.60.71.6-0.4-0.6-0.6-0.7-0.7-0.7-0.9-0.8-0.9-1.1-1.3
Number of licking bursts5.18.311.02.72.72.22.72.93.02.33.13.33.33.2
Context. condit. distance diff. score1.31.610.50.50.20.30.1-0.1-0.3-3.2-0.4-1.0-1.5-1.8
Locomotion velocity, session 10.40.50.7-0.9-0.7-0.8-0.8-0.8-0.70.1-0.7-0.5-0.5-0.5
Locomotion distance, session 10.60.81.7-1.1-1.2-1.3-1.1-1.0-0.80.5-0.8-0.5-0.4-0.2
Locomotion velocity, session 20.20.31.10.20.10.00.20.40.41.00.40.50.60.8
Locomotion distance, session 20.30.52.1-0.6-0.9-1.5-0.9-0.6-0.30.6-0.30.20.20.2
Locomotion velocity, session 30.50.52.2-0.2-0.4-0.2-0.4-0.4-0.5-1.5-0.5-0.8-0.9-1.0
Locomotion distance, session 30.10.10.3-0.1-0.3-0.5-0.3-0.2-0.2-0.6-0.2-0.2-0.2-0.3
Stereotopy head waving bouts, day 31.11.32.21.41.51.51.31.21.1-1.21.10.80.60.3
Stereotopy head waving duration, day 30.00.00.2-0.10.20.40.20.1-0.00.20.0-0.00.10.1
Locomotion velocity, session 70.20.30.5-0.7-0.6-0.5-0.6-0.5-0.50.5-0.5-0.4-0.3-0.2
Locomotion distance, session 70.20.30.8-0.5-0.6-0.9-0.7-0.6-0.5-0.2-0.5-0.4-0.5-0.5
Stereotopy head waving bouts, day 70.20.20.5-0.6-0.6-0.7-0.7-0.6-0.5-0.0-0.5-0.3-0.3-0.4
Stereotopy head waving duration, day 70.20.30.6-0.8-0.7-0.7-0.7-0.6-0.50.5-0.5-0.3-0.1-0.1
Locomotion velocity, session 80.10.10.20.40.20.40.30.50.4-0.30.40.20.20.3
Locomotion distance, session 80.30.42.80.70.30.40.30.30.2-1.70.1-0.2-0.5-0.7
Degree of sensitization distance0.20.21.6-0.5-0.4-0.5-0.3-0.3-0.21.3-0.2-0.00.20.3
Degree of sensitization stereotypy0.50.60.9-0.8-0.9-0.9-0.9-0.8-0.8-0.0-0.8-0.7-0.6-0.6
Conditioned locomotion0.50.61.1-0.4-0.6-0.4-0.6-0.6-0.7-1.0-0.8-0.9-1.0-1.0
Cocaine response after cond. corrected0.40.52.20.10.71.50.90.60.20.80.30.10.30.5
Cocaine response after cond. not corrected0.30.40.9-0.6-0.10.70.1-0.3-0.7-0.4-0.6-1.0-0.9-0.7
Cocaine response before conditioning3.64.47.3-1.5-1.7-1.9-1.9-2.0-1.9-2.7-2.0-2.1-2.4-2.6
Saline control response1.62.13.82.01.70.71.31.31.8-1.01.61.91.40.8
Bone: connectivity density2.03.19.02.32.12.12.01.71.4-3.01.30.5-0.0-0.4
Bone: cortical apparent density0.10.10.2-0.4-0.30.1-0.0-0.1-0.30.5-0.2-0.3-0.10.1
Bone: cortical area0.40.63.40.70.60.90.50.30.1-1.80.0-0.4-0.7-0.9
Bone: cortical porosity0.10.10.20.20.30.00.10.10.30.00.30.50.40.3
Bone: cortical porosity0.30.30.8-0.6-0.6-0.9-0.8-0.8-0.4-0.2-0.5-0.2-0.3-0.4
Bone: cortical thickness0.40.61.81.00.91.20.80.80.5-1.30.5-0.1-0.2-0.3
Bone: cortical thickness0.30.31.10.80.70.40.50.50.6-1.10.50.30.1-0.1
Bone: cortical tissue density0.10.10.3-0.4-0.30.1-0.0-0.1-0.30.5-0.2-0.2-0.00.2
Condit. Reinf. active minus inactive responses0.91.01.6-1.3-1.0-0.8-1.0-1.2-1.20.3-1.2-1.1-1.0-0.9
Condit. Reinf. active-inactive response ratio0.80.91.3-1.2-0.7-0.4-0.8-1.1-1.1-0.1-1.1-1.1-1.0-1.0
Condit. Reinf. active responses1.31.62.1-1.3-1.3-1.5-1.5-1.4-1.3-0.2-1.3-1.1-1.1-1.2
Condit. Reinf. inactive responses1.01.33.7-1.0-1.4-1.9-1.6-1.2-0.9-0.3-1.0-0.6-0.7-0.8
Incentive salience index mean1.72.12.7-1.5-1.5-1.5-1.6-1.6-1.6-0.3-1.6-1.5-1.4-1.5
Condit. Reinf. lever presses1.82.63.2-1.5-1.7-1.7-1.8-1.7-1.6-0.8-1.7-1.6-1.6-1.7
Condit. Reinf. active minus inactive responses0.30.41.01.00.70.50.60.70.7-0.50.60.50.30.1
Condit. Reinf. active-inactive response ratio0.20.30.40.60.50.10.40.60.60.20.60.60.60.5
Condit. Reinf. active responses0.20.32.00.50.20.00.0-0.0-0.0-1.4-0.1-0.3-0.6-0.9
Condit. Reinf. inactive responses0.50.72.4-0.2-0.3-0.3-0.5-0.7-0.6-1.6-0.7-0.8-1.1-1.3
Condit. Reinf. lever presses1.11.53.2-0.7-0.9-0.8-1.0-1.0-1.1-1.8-1.1-1.3-1.5-1.6
Condit. Reinf. lever reinforcers received0.20.31.30.2-0.1-0.3-0.2-0.2-0.2-1.2-0.3-0.4-0.6-0.8
Conditioned reinforcement - actives1.62.85.72.41.91.61.72.01.9-1.21.81.31.00.8
Conditioned reinforcement - inactives1.01.51.91.41.20.81.11.31.40.71.31.41.31.2
Conditioned locomotion0.50.64.41.10.50.10.30.40.5-2.10.30.0-0.4-0.8
Patch foraging indifference point 0 sec0.00.00.20.20.1-0.10.20.00.1-0.50.0-0.0-0.1-0.1
Patch foraging indifference point AUC1.11.63.01.71.31.11.31.61.5-0.11.41.21.10.9
Delay disc. indifference point, 0s delay0.20.21.50.10.51.20.60.50.0-0.00.1-0.2-0.10.4
Delay disc. indifference point, 16s delay0.20.30.7-0.3-0.8-0.6-0.5-0.3-0.5-0.4-0.5-0.5-0.4-0.6
Delay disc. indifference point, 2s delay4.65.17.3-2.7-2.3-1.8-2.3-2.5-2.6-0.6-2.6-2.5-2.3-2.0
Delay disc. indifference point, 24s delay0.10.10.6-0.2-0.6-0.4-0.4-0.1-0.20.8-0.1-0.10.10.1
Delay disc. indifference point, 4s delay2.62.83.6-1.8-1.7-1.4-1.7-1.7-1.9-0.6-1.8-1.9-1.8-1.6
Delay disc. indifference point, 8s delay0.80.91.7-0.9-1.2-1.3-1.1-1.0-0.9-0.4-1.0-0.9-0.8-0.9
Indifference point function ln k0.00.10.2-0.20.1-0.5-0.2-0.40.1-0.40.00.40.2-0.0
Indifference point function log k0.00.10.2-0.20.1-0.5-0.2-0.40.1-0.40.00.40.2-0.0
Patch foraging total patch changes 0 sec0.00.00.20.2-0.0-0.30.00.00.1-0.50.00.0-0.0-0.1
Patch foraging total patch changes 12 sec0.10.20.70.50.50.50.60.40.3-0.80.30.10.10.0
Patch foraging total patch changes 18 sec0.40.50.80.90.70.50.90.80.80.50.80.80.70.6
Patch foraging total patch changes 24 sec0.20.41.6-0.0-0.6-1.3-0.6-0.4-0.3-1.0-0.4-0.3-0.4-0.5
Patch foraging total patch changes 6 sec0.10.10.70.50.30.10.30.30.3-0.80.20.1-0.0-0.2
Patch foraging time to switch 0 sec0.51.12.9-1.7-1.00.3-0.5-0.9-1.41.3-1.1-1.3-0.8-0.2
Patch foraging water rate 0 sec0.81.63.81.91.50.31.01.01.6-1.51.31.40.90.2
Patch foraging water rate 12 sec0.20.31.20.1-0.2-1.1-0.6-0.5-0.0-1.1-0.20.1-0.2-0.7
Patch foraging water rate 18 sec0.91.53.9-1.0-1.1-2.0-1.6-1.5-0.9-1.0-1.0-0.6-0.8-1.1
Patch foraging water rate 24 sec0.40.51.80.90.8-0.10.20.20.9-1.30.70.90.4-0.3
Patch foraging water rate 6 sec0.71.03.1-0.3-0.5-1.3-0.9-1.0-0.5-1.8-0.7-0.6-1.0-1.4
Seeking ratio, delayed vs. immediate footshock1.01.28.1-0.10.10.00.50.30.42.80.50.91.21.3
Distance traveled before self-admin1.31.72.2-1.5-1.4-1.5-1.4-1.5-1.4-0.2-1.4-1.2-1.1-1.1
Distance traveled after self-admin0.50.61.3-0.4-0.9-1.2-1.0-0.7-0.6-0.8-0.7-0.7-0.8-0.8
Extensor digitorum longus weight1.14.420.02.82.12.21.71.71.4-4.51.10.1-0.8-1.4
Bone: elastic displacement0.20.20.40.60.60.30.40.50.6-0.60.50.50.40.3
Bone: elastic work1.31.84.51.81.61.41.31.31.3-2.11.20.80.40.1
Bone: endosteal estimation0.61.42.51.61.40.91.21.21.4-0.81.31.31.00.7
Bone: endosteal perimeter0.30.54.20.50.3-0.00.0-0.10.1-2.1-0.1-0.2-0.6-1.0
Epididymis fat weight0.41.52.6-0.8-1.0-0.6-1.1-1.0-1.2-1.6-1.2-1.4-1.5-1.6
Delta time in closed arm before/after self-admin0.10.00.10.30.2-0.10.10.10.30.20.20.40.2-0.1
Delta time in open arm before/after self-admin2.92.95.2-2.3-1.8-1.4-1.7-2.1-2.00.5-1.9-1.7-1.4-1.2
Diff in mean of infusions in LGA sessions0.20.21.50.0-0.1-0.1-0.2-0.2-0.1-1.2-0.2-0.3-0.4-0.6
Delay discount exponential model param1.92.13.11.61.81.51.61.51.60.31.61.51.41.3
Extinction: sum of active levers before priming1.01.11.9-0.9-1.1-0.7-1.0-0.9-1.2-0.5-1.2-1.4-1.3-1.2
Active lever presses in extinction session 60.10.10.30.3-0.1-0.1-0.10.1-0.1-0.5-0.1-0.4-0.5-0.5
Bone: final force1.93.04.82.22.12.01.91.91.9-0.81.81.51.21.0
Bone: final moment1.72.74.22.02.01.91.81.81.8-0.61.71.51.21.0
Food consumed during 24 hour testing period0.70.91.50.81.00.60.90.81.00.91.01.21.11.0
Glucose0.50.81.7-1.3-1.2-0.8-0.9-0.9-1.10.4-1.0-0.9-0.6-0.3
Heart weight0.10.20.50.70.2-0.5-0.00.30.6-0.70.50.70.40.2
Delay discount hyperbolic model param1.92.12.91.61.71.51.51.51.60.41.61.51.41.3
Intermittent access intake day 1-15 change1.63.34.82.21.91.71.92.22.00.52.01.81.71.7
Intermittent access intake escalation1.73.55.02.21.91.72.02.22.10.62.01.81.81.8
Intermittent access intake escalation 21.11.21.71.10.90.91.01.31.11.11.21.11.21.3
Intermitt. access day 1 inactive lever presses0.31.31.71.21.00.81.01.31.30.71.31.31.31.3
Intermitt. access day 15 inactive lever presses0.00.10.6-0.40.10.70.40.0-0.20.3-0.0-0.2-0.00.2
Intermitt. access escalation Index0.81.11.8-0.9-1.1-1.3-1.2-1.2-1.0-0.7-1.0-0.8-0.9-1.1
Intermittent access day 1 total infusions0.61.02.1-1.0-1.1-1.4-1.4-1.2-0.9-0.3-1.0-0.7-0.7-0.8
Intermittent access day 15 total infusions0.10.10.20.40.1-0.2-0.10.30.4-0.20.30.40.30.2
Intermittent access terminal intake (last 3 days)0.00.00.10.30.0-0.10.00.20.20.20.20.20.20.3
Intermittent access total infusions0.30.30.5-0.5-0.6-0.7-0.7-0.6-0.6-0.3-0.6-0.6-0.6-0.6
Intermittent access day 1 locomotion2.83.64.8-1.8-1.9-2.1-2.2-2.1-1.9-1.2-1.9-1.7-1.8-1.9
Intermittent access day 15 total locomotion0.51.02.4-0.3-0.8-1.5-1.2-0.9-0.5-1.5-0.7-0.5-0.8-1.1
Intermittent access total locomotion1.92.33.6-1.3-1.5-1.9-1.8-1.7-1.4-1.1-1.5-1.3-1.4-1.6
Intermittent access standard deviation0.71.52.11.11.21.31.41.51.21.01.21.01.21.4
Left kidney weight3.918.332.35.75.35.44.94.74.3-4.54.02.61.71.0
Right kidney weight3.515.828.15.05.15.34.74.33.9-3.63.82.71.81.2
Cocaine induced anxiety1.01.52.2-0.9-1.2-0.9-1.1-1.1-1.2-1.0-1.3-1.5-1.5-1.4
Post-drug Anxiety3.73.96.3-2.5-2.1-1.2-1.7-2.0-2.40.0-2.3-2.4-2.1-1.6
Baseline Anxiety0.60.73.9-1.4-0.50.2-0.1-0.5-0.72.0-0.5-0.30.20.7
Tail length4.216.426.25.15.05.14.64.34.0-4.53.82.71.91.1
Length with tail7.833.858.97.77.17.26.76.45.9-5.75.63.92.71.8
Length without tail5.317.028.95.45.05.24.94.74.2-3.44.02.72.01.5
Times rat made contact with spout0.80.91.70.91.30.81.00.71.1-0.01.01.21.00.7
Lifetime Intake0.40.50.6-0.8-0.7-0.6-0.8-0.8-0.8-0.0-0.7-0.7-0.6-0.6
Liver weight, left4.88.011.43.23.43.23.23.13.10.23.02.72.42.1
Liver weight, right0.81.32.81.41.51.71.31.11.1-1.31.00.60.3-0.0
Locomotor activity0.60.92.81.41.00.40.70.81.0-1.70.90.80.30.1
Locomotor testing distance0.40.81.21.11.10.60.90.81.0-0.71.01.00.70.4
Locomotor testing rearing0.00.10.2-0.40.20.0-0.1-0.5-0.2-0.1-0.20.0-0.1-0.2
Locomotion in novel chamber0.70.91.91.41.00.20.80.91.2-0.21.11.31.00.7
Locomotion in novel chamber post-restriction0.30.42.00.90.6-0.20.40.30.7-1.40.50.70.3-0.1
Fecal boli incidents, locomotor time 10.50.72.51.20.90.50.70.60.8-1.60.70.60.2-0.2
Change in fecal boli incidents, locomotor task0.40.41.30.10.40.80.60.60.31.20.50.40.70.8
Time >=10cm from walls, locomotor time 12.52.73.7-1.9-1.6-1.2-1.6-1.8-1.9-0.6-1.8-1.8-1.7-1.6
Bouts of movement, locomotor time 10.80.92.01.41.00.91.01.11.1-0.91.00.90.60.4
Total resting periods, locomotor time 10.70.81.71.31.00.80.91.01.0-0.90.90.70.50.3
Rest time, locomotor task time 10.50.72.40.91.01.00.90.70.6-1.60.60.3-0.0-0.3
Distance moved, locomotor task time 10.30.41.0-0.7-0.7-1.0-0.8-0.6-0.60.7-0.5-0.3-0.20.1
Vertical activity count, locomotor time 10.00.10.20.4-0.0-0.30.00.30.30.30.20.30.30.5
Time >=10cm from walls, locomotor time 20.81.23.3-0.7-0.40.2-0.5-0.8-1.0-1.8-1.0-1.3-1.4-1.5
Bouts of movement, locomotor time 20.20.42.70.40.0-0.1-0.1-0.1-0.0-1.6-0.1-0.3-0.6-1.0
Total resting periods, locomotor time 20.20.32.20.50.20.20.10.10.1-1.50.0-0.2-0.5-0.8
Rest time, locomotor task time 20.60.81.3-0.9-0.7-0.7-0.8-1.0-0.9-0.8-0.9-0.8-0.9-1.1
Distance moved, locomotor task time 21.72.14.21.31.20.91.31.51.41.21.51.51.72.0
Vertical activity count, locomotor time 23.14.26.72.62.01.62.02.52.30.12.32.12.02.0
Light reinforcement 10.82.13.0-1.6-1.7-1.5-1.6-1.5-1.60.0-1.6-1.5-1.3-1.0
Light reinforcement 20.10.21.10.0-0.0-0.10.10.20.21.10.20.40.50.7
Bone: marrow area0.71.42.41.61.40.91.21.21.4-0.81.31.31.00.7
Bone: maximum diameter0.40.72.90.90.91.00.70.60.5-1.70.40.0-0.3-0.5
Bone: maximum force1.01.73.11.81.61.51.41.41.4-1.51.31.00.60.3
Bone: maximum moment0.91.62.81.71.61.41.31.31.3-1.21.21.00.70.4
Mean time between licks in bursts0.61.42.7-1.4-1.5-1.7-1.5-1.3-1.10.1-1.1-0.8-0.7-0.6
Mean num. licks in bursts1.62.53.8-1.4-1.2-1.1-1.4-1.7-1.6-1.6-1.7-1.7-1.8-1.9
Cd content in liver0.30.31.9-0.2-0.7-1.4-1.0-0.5-0.1-0.1-0.30.1-0.0-0.2
Co content in liver2.22.54.21.41.20.61.11.41.71.71.72.12.01.9
Cu content in liver0.10.10.5-0.1-0.3-0.7-0.4-0.3-0.2-0.1-0.2-0.1-0.2-0.3
Fe content in liver2.83.47.7-0.9-1.3-1.4-1.6-1.6-1.5-2.8-1.7-1.9-2.3-2.5
K content in liver0.50.50.8-0.7-0.6-0.3-0.7-0.7-0.8-0.4-0.8-0.9-0.9-0.8
Mg content in liver0.30.30.30.60.60.60.40.60.60.10.50.50.50.5
Mn content in liver0.80.92.50.50.60.60.60.80.81.60.91.01.21.3
Na content in liver0.40.40.70.80.80.80.80.70.6-0.60.60.30.20.2
Rb content in liver4.35.07.6-2.5-2.8-2.6-2.7-2.4-2.40.2-2.4-2.1-1.9-1.6
Se content in liver3.44.07.4-1.3-1.2-0.2-1.3-1.6-2.0-2.7-2.0-2.6-2.7-2.7
Sr content in liver2.62.32.81.51.41.41.61.71.61.01.61.51.61.7
Zn content in liver2.12.34.32.11.81.71.51.81.7-0.51.61.31.10.8
Bone: minimum diameter0.00.00.2-0.00.2-0.10.10.00.20.40.20.30.30.2
Time in familiar zone, hab. session 10.20.20.7-0.20.40.50.40.10.10.90.20.30.50.5
Time in novel zone, hab. session 10.10.10.40.50.20.20.20.40.3-0.70.20.0-0.0-0.1
Total zone transitions, hab. session 11.21.73.7-1.2-1.7-1.9-1.7-1.2-1.20.5-1.2-1.0-0.9-0.8
Total locomotion distance, hab. session 11.92.73.5-1.5-1.9-1.6-1.8-1.5-1.8-0.5-1.8-1.9-1.7-1.6
Locomotion velocity, hab. session 12.63.75.4-1.9-2.3-2.1-2.2-1.9-2.1-0.2-2.1-2.1-1.9-1.6
Time in familiar zone, hab. session 20.10.10.3-0.30.00.50.1-0.1-0.30.0-0.2-0.3-0.2-0.1
Time in novel zone, hab. session 20.20.20.9-0.4-0.6-1.0-0.6-0.5-0.3-0.1-0.3-0.2-0.2-0.2
Total zone transitions, hab. session 20.70.91.41.00.80.40.81.01.10.61.11.21.21.1
Total locomotion distance, hab. session 20.10.10.3-0.1-0.4-0.6-0.4-0.2-0.10.3-0.1-0.1-0.00.0
Locomotion velocity, hab. session 20.10.10.30.0-0.3-0.5-0.20.00.00.50.00.10.20.3
Novel to familiar place preference ratio0.50.50.90.40.60.40.60.50.70.80.70.90.91.0
Novelty place preference0.30.30.90.10.30.10.30.30.40.90.50.70.80.8
Time in novel zone, NPP test0.30.30.60.20.40.20.40.40.50.70.50.70.80.8
Total zone transitions, NPP test0.00.00.10.2-0.1-0.3-0.2-0.00.1-0.40.00.1-0.0-0.1
Total locomotion distance, NPP test1.62.22.9-1.1-1.4-1.3-1.5-1.4-1.5-1.4-1.5-1.6-1.7-1.7
Locomotion velocity, NPP test1.21.72.4-0.9-1.3-1.4-1.4-1.3-1.2-1.3-1.3-1.3-1.5-1.5
Intraocular pressure0.40.64.10.70.30.20.20.10.1-2.0-0.0-0.3-0.7-0.9
Delta distance traveled before/after self-admin1.01.11.91.40.90.80.91.31.20.31.21.11.01.1
Delta ambulatory time before/after self-admin0.30.30.70.50.30.20.30.60.60.80.60.60.70.7
Parametrial fat weight0.10.21.0-0.10.21.00.30.2-0.2-0.4-0.1-0.6-0.4-0.1
Pavlov. Cond. lever latency2.73.44.92.12.22.12.22.02.0-0.32.01.81.61.4
Pavlov. Cond. magazine entry latency0.00.10.40.20.20.10.00.00.1-0.70.10.0-0.1-0.3
Pavlov. Cond. change in total contacts1.11.21.6-1.2-1.2-0.7-1.1-1.1-1.30.0-1.2-1.3-1.1-1.0
Pavlov. Cond. index score0.70.91.2-0.9-0.9-0.8-1.0-1.0-1.0-0.5-1.0-1.0-1.0-1.1
Pavlov. Cond. latency score1.01.31.6-1.2-1.2-1.0-1.2-1.2-1.2-0.4-1.2-1.2-1.2-1.2
Pavlov. Cond. lever contacts2.42.83.9-1.9-2.0-1.8-2.0-1.8-1.80.3-1.8-1.6-1.4-1.3
Pavlov. Cond. magazine entry number0.30.41.30.30.30.40.60.60.51.10.60.60.81.0
Pavlov. Cond. intertrial magazine entries0.40.51.7-0.8-0.9-1.3-0.9-0.7-0.40.7-0.4-0.10.00.0
Pavlov. Cond. lever-magazine prob. diff.0.70.81.1-0.9-0.9-0.7-1.0-1.0-1.0-0.5-1.0-1.0-1.0-1.0
Pavlov. Cond. response bias0.50.61.1-0.5-0.6-0.7-0.8-0.8-0.7-0.8-0.8-0.8-0.9-1.1
Pavlov. Cond. lever latency1.41.92.21.21.41.41.41.41.41.11.41.41.51.5
Pavlov. Cond. magazine entry latency2.63.14.0-2.0-2.0-1.8-2.0-1.9-1.9-0.1-1.9-1.8-1.7-1.5
Pavlov. Cond. change in total contacts0.50.91.9-0.7-1.1-1.4-1.1-0.9-0.8-0.5-0.9-0.8-0.8-0.9
Pavlov. Cond. index score2.02.84.0-1.6-1.9-2.0-1.9-1.8-1.7-0.5-1.7-1.6-1.6-1.5
Pavlov. Cond. latency score2.12.73.6-1.6-1.8-1.9-1.9-1.8-1.7-0.6-1.7-1.6-1.6-1.5
Pavlov. Cond. lever contacts2.12.83.3-1.5-1.7-1.7-1.7-1.8-1.7-1.3-1.8-1.7-1.8-1.8
Pavlov. Cond. magazine entry number1.82.33.61.61.81.91.81.61.6-0.31.61.41.31.1
Pavlov. Cond. intertrial magazine entries0.60.81.31.11.10.71.00.81.0-0.31.01.10.80.6
Pavlov. Cond. lever-magazine prob. diff.2.02.74.2-1.6-1.9-2.0-1.9-1.8-1.6-0.4-1.7-1.5-1.5-1.4
Pavlov. Cond. response bias3.44.75.7-2.0-2.3-2.4-2.4-2.3-2.2-1.1-2.3-2.2-2.2-2.2
Time in closed arm before self-admin2.53.25.42.31.81.31.72.22.1-0.22.01.81.71.7
Time in closed arm after self-admin2.22.34.62.11.40.61.21.71.9-0.21.81.91.51.3
Time in open arm before self-admin0.10.10.3-0.2-0.4-0.5-0.4-0.3-0.3-0.1-0.3-0.2-0.4-0.4
Time in open arm after self-admin1.92.13.8-1.9-1.4-0.9-1.3-1.7-1.80.0-1.7-1.6-1.4-1.3
Bone: periosteal estimation0.61.22.41.51.41.21.21.11.1-1.61.00.70.30.0
Bone: periosteal perimeter0.81.45.6-0.3-0.4-0.5-0.7-0.9-0.8-2.4-0.9-1.1-1.4-1.7
Bone: post-yield work0.40.61.8-0.2-0.4-0.5-0.5-0.6-0.6-1.3-0.6-0.8-1.0-1.2
Progressive ratio test 1 active lever presses0.70.81.71.31.00.90.91.11.0-0.51.00.80.60.5
Progressive ratio test 1 breakpoint0.70.81.71.31.00.91.01.11.0-0.51.00.80.60.6
Progressive ratio test 1 inactive lever presses1.11.62.51.61.20.81.01.41.50.11.51.51.31.2
Progressive ratio test 2 active lever presses1.31.63.01.71.20.81.11.51.5-0.01.41.31.21.1
Progressive ratio test 2 breakpoint1.21.42.81.71.10.71.01.41.40.01.41.31.11.0
Progressive ratio test 2 inactive lever presses1.32.14.02.01.70.91.31.51.8-0.91.71.71.20.8
Incentive Sensitization - Responses0.10.20.40.40.20.10.30.50.50.60.50.50.50.6
Incentive Sensitization - Breakpoint0.10.10.40.30.10.00.10.40.30.60.30.40.40.5
Sum of active levers in priming session hrs 5-60.30.31.0-0.1-0.30.3-0.0-0.0-0.5-0.7-0.5-1.0-0.9-0.6
Progressive ratio0.30.53.0-0.20.10.20.10.20.31.70.40.70.91.1
Food seeking constrained by brief footshock0.30.32.7-0.6-0.2-0.3-0.2-0.3-0.31.6-0.20.00.20.4
Seeking ratio, punishment vs. effort0.10.10.40.60.40.20.50.30.3-0.70.2-0.0-0.2-0.3
Retroperitoneal fat weight0.73.16.0-1.7-1.4-0.2-1.3-1.5-2.0-1.3-2.0-2.5-2.3-2.0
Reaction time number correct0.40.91.91.40.90.30.81.11.20.01.11.10.90.6
Reaction time mean minus median1.64.06.4-1.7-1.6-1.5-1.8-2.2-1.9-2.5-2.0-1.9-2.2-2.5
Reaction time mean minus median AUC1.23.04.3-1.7-1.7-1.9-2.0-2.1-1.6-1.4-1.7-1.4-1.6-1.8
Reaction time num false alarms0.91.21.9-1.1-1.0-1.3-1.2-1.4-1.0-0.9-1.1-0.8-1.0-1.2
Reaction time num false alarms AUC1.01.62.2-1.1-1.1-1.4-1.3-1.5-1.2-1.3-1.2-1.1-1.3-1.5
Reaction time trials correct on left0.40.91.91.40.90.30.81.11.20.01.11.10.90.6
Reaction time trials on left0.40.81.71.30.80.30.71.01.10.01.11.00.80.6
Reaction time mean1.82.95.5-2.3-2.0-1.4-1.9-2.0-2.00.4-1.9-1.6-1.3-1.1
Reaction time mean AUC2.13.35.8-2.4-2.1-1.6-2.0-2.1-2.10.3-2.0-1.7-1.4-1.2
Median of all reaction times1.52.24.9-2.2-1.8-1.2-1.6-1.6-1.71.4-1.5-1.2-0.8-0.4
Reaction time omissions1.62.33.8-1.9-1.5-1.4-1.7-1.9-1.6-0.7-1.6-1.3-1.4-1.4
Reaction time false alarm rate1.82.53.5-1.6-1.4-1.4-1.6-1.9-1.6-1.3-1.7-1.5-1.7-1.7
Reaction time premature initiation rate0.20.30.3-0.5-0.5-0.6-0.6-0.6-0.6-0.0-0.6-0.6-0.6-0.5
Reaction time premature initiations0.00.00.20.1-0.1-0.4-0.2-0.1-0.00.1-0.1-0.1-0.2-0.2
Std. dev. reaction times1.93.54.9-2.1-1.8-1.5-2.0-2.2-2.0-1.3-2.0-1.8-1.9-2.0
Reaction time trials completed0.40.81.71.30.80.30.71.01.10.01.11.00.80.6
Reaction time trials AUC0.20.41.11.00.5-0.00.40.70.9-0.10.80.80.60.3
Run reversals in cocaine runway, females0.60.60.9-0.9-1.0-0.7-0.8-0.7-0.9-0.2-0.9-0.9-0.8-0.6
Run reversals in cocaine runway, males0.20.20.70.40.1-0.8-0.10.10.50.30.50.80.70.5
Latency to leave start box in cocaine runway0.20.20.40.10.30.70.40.50.20.50.30.20.40.6
Latency to leave start box in cocaine runway, F1.61.93.11.21.31.81.61.71.30.91.41.01.21.5
Latency to leave start box in cocaine runway, M0.80.71.2-1.0-0.9-1.1-1.0-1.0-0.9-0.3-0.9-0.7-0.7-0.7
Std. dev. time between licks in bursts0.30.41.8-0.1-0.4-0.8-0.7-0.5-0.3-1.3-0.4-0.3-0.5-0.8
Total sessions with >9 infusions0.00.10.4-0.30.00.30.00.0-0.10.6-0.0-0.00.20.3
Short access day 1 total inactive lever presses0.20.30.60.20.70.80.50.30.40.30.50.50.50.5
Short access day 10 total inactive lever presses1.33.25.51.82.12.32.22.01.80.01.91.51.41.4
Short access day 1 total infusions0.30.31.1-1.1-0.5-0.2-0.5-0.7-0.70.7-0.6-0.5-0.3-0.0
Short access day 10 total infusions1.01.21.6-1.2-1.0-0.7-1.1-1.2-1.2-0.5-1.2-1.2-1.2-1.1
Short access total infusions0.40.51.3-1.1-0.6-0.1-0.5-0.7-0.90.7-0.8-0.8-0.5-0.3
Short access day 1 locomotion0.91.11.8-1.2-1.0-1.1-1.2-1.3-1.1-0.3-1.1-0.9-0.9-1.0
Short access day 10 total locomotion0.00.10.2-0.3-0.0-0.4-0.3-0.4-0.2-0.2-0.20.0-0.1-0.2
Short access total locomotion1.11.32.1-1.5-1.1-1.0-1.2-1.4-1.3-0.1-1.3-1.1-1.0-1.0
One hour access (0.3 mA shock)1.21.42.71.51.10.10.71.11.5-0.21.41.61.30.9
Compulsive drug intake0.50.61.4-1.0-1.0-1.2-0.9-0.7-0.61.1-0.6-0.20.00.2
One hour access (shock baseline)0.40.51.61.20.80.20.40.60.9-1.30.70.70.3-0.1
Social response proportion3.03.46.42.52.12.02.12.22.0-0.71.91.51.31.1
Social responses0.40.53.01.10.60.10.40.50.6-1.70.50.3-0.1-0.4
Social time0.70.92.0-1.3-1.1-1.4-1.1-1.0-0.81.4-0.8-0.3-0.00.2
Soleus weight0.41.06.91.00.40.40.40.30.2-2.60.0-0.5-1.0-1.3
Bone: stiffness0.10.20.90.60.40.10.20.20.3-1.00.20.2-0.1-0.3
Tibialis anterior weight1.65.519.03.12.63.02.32.11.7-4.41.50.3-0.5-1.0
Time to tail flick, vehicle, before self-admin0.30.30.6-0.6-0.7-0.1-0.4-0.2-0.70.7-0.6-0.8-0.5-0.2
Time to tail flick, vehicle, after self-admin0.00.00.10.0-0.2-0.3-0.2-0.1-0.10.4-0.1-0.1-0.0-0.0
Time to tail flick, test, before self-admin2.82.94.02.01.81.71.82.01.9-0.21.91.71.61.5
Time to tail flick, test, after self-admin0.10.10.3-0.3-0.30.1-0.10.1-0.30.5-0.2-0.4-0.20.2
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.4-0.4-0.7-0.5-0.6-0.3-0.3-0.4-0.2-0.3-0.4
Delta time to tail flick, test, before/after SA1.61.62.4-1.5-1.4-1.2-1.3-1.4-1.50.5-1.4-1.3-1.1-1.0
Tibia length5.114.120.94.44.44.64.44.33.90.03.93.22.92.8
Ambulatory time before self-admin1.72.63.2-1.5-1.5-1.7-1.6-1.7-1.6-1.3-1.7-1.6-1.6-1.8
Ambulatory time after self-admin0.91.11.5-0.8-1.1-1.2-1.2-1.0-1.0-0.9-1.0-1.0-1.1-1.2
Bone: tissue strength0.50.50.70.70.70.80.80.80.70.30.80.70.80.8
Total heroin consumption5.05.87.4-2.5-2.7-2.6-2.7-2.6-2.60.0-2.6-2.4-2.3-2.2
Bone: trabecular number1.01.76.31.51.51.71.51.10.8-2.50.80.1-0.3-0.5
Bone: trabecular spacing1.72.33.9-1.9-1.8-2.0-1.8-1.7-1.41.9-1.3-0.8-0.5-0.3
Bone: trabecular thickness1.31.611.41.00.71.00.60.50.2-3.40.1-0.6-1.1-1.4
Bone: trabecular tissue density0.71.01.8-0.7-0.9-0.6-1.0-0.9-1.0-1.3-1.0-1.1-1.2-1.2
Water consumed over 24 hours3.85.27.32.42.72.02.52.22.50.72.52.62.32.0
Number of responses in last shaping day0.20.20.6-0.8-0.4-0.4-0.5-0.7-0.60.1-0.5-0.4-0.3-0.3