Hub : Genes

LOC102552504

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability LOC102552504 0.02 0.02 2.7e-03 0.01 0.02 0.01 0.01 8.1e-03 2.9e-03 6.6e-02 1.2e-02
2 BLA gene expression LOC102552504 0.08 0.05 2.3e-05 0.07 0.09 0.07 0.07 8.1e-05 2.8e-05 1.6e-04 1.0e-04
3 pVTA intron excision ratio chr8_119957747_119958158 0.03 0.03 7.0e-03 0.03 0.01 0 0.03 1.1e-03 2.5e-02 2.9e-01 3.6e-03
4 IC intron excision ratio chr8_119958714_119959796 0.08 0.08 9.4e-03 0.02 0.02 -0.01 0 5.5e-02 4.7e-02 6.6e-01 2.1e-01
5 pVTA intron excision ratio chr8_119957747_119958652 0.03 0.03 8.3e-03 0.02 0.01 0.01 0.02 8.5e-03 2.8e-02 8.1e-02 7.8e-03
6 IC gene expression LOC102552504 0.06 0.05 4.7e-03 0.04 0.05 0.04 0.04 6.5e-03 3.0e-03 1.1e-02 9.2e-03
7 OFC gene expression LOC102552504 0.6 0.18 1.3e-06 0.19 0.16 0.14 0.15 2.8e-05 1.7e-04 3.9e-04 1.7e-04
8 NAcc gene expression LOC102552504 0.09 0.04 0.0e+00 0.12 0.14 0.14 0.14 3.0e-18 4.9e-21 6.7e-20 6.2e-20
9 PL intron excision ratio chr8_119957747_119958158 0.05 0.04 7.6e-04 0.01 0.01 0 0.01 7.7e-03 2.7e-02 7.9e-02 3.7e-02
10 PL intron excision ratio chr8_119957747_119958652 0.04 0.04 2.5e-03 0.01 0.01 0 0.01 1.2e-02 5.9e-02 1.1e-01 6.8e-02
11 pVTA intron excision ratio chr8_119965148_119967006 0.09 0.07 4.1e-03 0.04 0.02 0.06 0.06 2.1e-04 7.0e-03 1.4e-05 2.6e-05
12 PL gene expression LOC102552504 0.45 0.15 0.0e+00 0.21 0.22 0.22 0.22 8.7e-23 4.4e-24 2.1e-23 9.8e-24

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.00.10.8-0.00.0-0.1-0.10.1-0.1-0.2-0.20.0-0.00.9-0.2
Area under the delay curve1.51.82.5-1.51.5-1.3-1.61.31.41.41.3-1.31.3-0.61.2
BMI with tail0.30.92.30.8-0.91.50.9-1.5-0.9-1.0-0.71.0-1.0-0.1-0.4
BMI without tail0.61.83.21.3-1.31.81.3-1.8-1.4-1.3-1.41.2-1.21.1-0.9
Body weight5.524.027.95.1-5.15.35.1-5.3-5.0-5.1-4.85.1-5.13.0-4.3
Weight adjusted by age0.00.00.10.1-0.10.20.2-0.2-0.0-0.20.10.2-0.2-0.30.0
Bone surface0.10.20.3-0.40.4-0.3-0.50.30.40.40.4-0.50.50.00.5
Bone volume0.00.10.4-0.20.3-0.1-0.30.10.20.20.1-0.30.30.60.3
Breakpoint value in progressive ratio session0.30.30.8-0.50.5-0.9-0.50.90.40.60.3-0.60.60.40.5
Number of licking bursts0.20.31.4-0.40.3-0.5-0.30.40.40.40.6-0.40.4-1.20.3
Context. condit. distance diff. score0.00.00.10.0-0.0-0.20.00.20.00.10.1-0.10.10.10.1
Locomotion velocity, session 10.10.10.4-0.20.2-0.2-0.30.20.20.60.2-0.50.50.10.3
Locomotion distance, session 10.81.03.31.0-0.90.90.9-0.9-1.0-0.7-1.20.7-0.71.8-0.6
Locomotion velocity, session 20.30.40.9-0.60.6-0.6-0.60.60.60.70.6-0.60.60.10.9
Locomotion distance, session 20.10.11.2-0.10.10.1-0.2-0.1-0.00.3-0.2-0.30.31.10.3
Locomotion velocity, session 30.20.22.00.3-0.20.40.2-0.3-0.3-0.1-0.50.0-0.01.40.2
Locomotion distance, session 30.80.81.6-0.91.0-0.8-1.00.80.90.80.7-0.90.90.91.3
Stereotopy head waving bouts, day 30.30.33.00.3-0.30.50.4-0.5-0.1-0.10.10.1-0.1-1.7-0.2
Stereotopy head waving duration, day 30.40.51.60.6-0.70.80.7-0.8-0.5-0.5-0.30.5-0.5-1.3-0.9
Locomotion velocity, session 70.70.73.10.6-0.60.90.5-0.9-0.7-0.7-0.90.6-0.61.8-0.7
Locomotion distance, session 70.30.30.6-0.70.7-0.4-0.80.40.60.60.5-0.70.70.20.5
Stereotopy head waving bouts, day 70.10.10.2-0.40.4-0.3-0.40.30.30.40.2-0.40.40.50.4
Stereotopy head waving duration, day 70.20.21.20.3-0.30.40.3-0.4-0.4-0.2-0.50.3-0.31.1-0.2
Locomotion velocity, session 80.40.53.80.5-0.40.50.4-0.4-0.5-0.3-0.70.3-0.31.90.1
Locomotion distance, session 80.30.53.70.5-0.40.40.4-0.4-0.6-0.2-0.80.1-0.11.9-0.0
Degree of sensitization distance1.41.42.41.2-1.21.31.2-1.3-1.2-1.2-1.11.1-1.10.0-1.6
Degree of sensitization stereotypy0.20.21.6-0.30.3-0.3-0.40.30.10.2-0.1-0.20.21.30.3
Conditioned locomotion3.13.64.4-2.12.1-2.0-2.12.02.01.91.9-1.81.8-1.01.8
Cocaine response after cond. corrected0.40.51.20.6-0.71.10.7-1.1-0.5-0.5-0.30.5-0.5-1.1-0.6
Cocaine response after cond. not corrected1.72.03.31.5-1.61.81.6-1.8-1.4-1.2-1.21.3-1.3-0.2-1.3
Cocaine response before conditioning1.01.12.71.2-1.10.81.1-0.8-1.2-0.9-1.20.9-0.91.6-0.7
Saline control response0.81.11.71.0-1.00.80.9-0.8-1.0-1.2-1.11.2-1.21.1-1.3
Bone: connectivity density0.40.61.0-0.80.8-1.0-0.91.00.70.60.6-0.70.7-0.10.4
Bone: cortical apparent density0.40.61.3-0.70.7-1.1-0.81.10.70.70.5-0.70.70.20.7
Bone: cortical area0.10.10.2-0.30.2-0.4-0.20.40.30.20.5-0.30.3-0.30.4
Bone: cortical porosity0.10.10.3-0.40.5-0.4-0.60.30.30.30.1-0.20.20.4-0.2
Bone: cortical porosity0.10.10.2-0.30.3-0.2-0.40.20.20.10.0-0.10.10.2-0.4
Bone: cortical thickness0.10.10.30.5-0.50.20.6-0.2-0.3-0.5-0.20.5-0.50.1-0.1
Bone: cortical thickness0.00.00.10.1-0.1-0.30.10.3-0.1-0.1-0.10.1-0.10.2-0.1
Bone: cortical tissue density0.40.61.3-0.70.7-1.1-0.81.10.70.70.5-0.70.70.20.8
Condit. Reinf. active minus inactive responses0.10.10.30.3-0.40.20.4-0.2-0.3-0.4-0.20.4-0.4-0.2-0.5
Condit. Reinf. active-inactive response ratio0.30.30.60.6-0.60.30.6-0.3-0.5-0.7-0.40.6-0.6-0.2-0.8
Condit. Reinf. active responses0.00.00.2-0.20.2-0.1-0.20.10.20.20.3-0.30.3-0.40.1
Condit. Reinf. inactive responses0.70.91.3-1.01.0-0.6-1.00.61.01.10.9-1.11.1-0.51.1
Incentive salience index mean0.00.00.1-0.20.2-0.1-0.20.10.20.20.3-0.30.3-0.30.2
Condit. Reinf. lever presses1.21.72.1-1.31.4-1.0-1.41.01.31.41.3-1.51.5-0.81.4
Condit. Reinf. active minus inactive responses1.52.02.41.5-1.51.41.6-1.4-1.4-1.4-1.41.4-1.41.1-1.1
Condit. Reinf. active-inactive response ratio1.51.83.11.4-1.41.81.4-1.8-1.3-1.2-1.21.2-1.20.3-1.0
Condit. Reinf. active responses1.11.52.11.4-1.41.01.4-1.0-1.3-1.3-1.21.3-1.30.5-1.1
Condit. Reinf. inactive responses0.20.31.0-0.30.3-1.0-0.31.00.40.30.4-0.40.4-0.60.3
Condit. Reinf. lever presses1.92.63.21.8-1.81.31.8-1.3-1.7-1.8-1.71.7-1.71.4-1.4
Condit. Reinf. lever reinforcers received1.52.12.71.6-1.61.21.6-1.2-1.5-1.6-1.41.5-1.50.8-1.3
Conditioned reinforcement - actives1.62.73.8-1.41.5-1.9-1.41.91.52.01.5-1.71.7-2.00.9
Conditioned reinforcement - inactives2.33.46.5-1.51.5-1.9-1.41.91.61.91.8-2.12.1-2.51.5
Conditioned locomotion0.40.51.0-0.60.6-1.0-0.71.00.61.00.6-0.70.7-0.70.2
Patch foraging indifference point 0 sec1.22.33.71.4-1.41.11.3-1.1-1.4-1.7-1.61.7-1.71.9-1.6
Patch foraging indifference point AUC0.20.22.20.00.0-0.3-0.10.3-0.1-0.1-0.40.3-0.31.5-0.1
Delay disc. indifference point, 0s delay0.10.10.20.1-0.10.30.1-0.3-0.1-0.4-0.10.4-0.40.1-0.4
Delay disc. indifference point, 16s delay0.91.01.3-1.11.1-1.0-1.11.01.01.01.0-0.90.9-0.51.0
Delay disc. indifference point, 2s delay0.30.30.4-0.60.6-0.6-0.60.60.60.60.5-0.70.7-0.30.4
Delay disc. indifference point, 24s delay1.11.31.8-1.11.1-1.2-1.21.21.11.31.0-1.21.2-0.80.9
Delay disc. indifference point, 4s delay1.71.82.2-1.51.5-1.4-1.51.41.41.41.3-1.21.2-0.91.3
Delay disc. indifference point, 8s delay1.51.72.5-1.51.5-1.2-1.61.31.41.31.3-1.11.1-0.71.2
Indifference point function ln k0.20.30.7-0.30.3-0.0-0.30.00.40.60.6-0.60.6-0.70.9
Indifference point function log k0.20.30.7-0.30.3-0.0-0.30.00.40.60.6-0.60.6-0.70.9
Patch foraging total patch changes 0 sec1.42.53.41.5-1.51.21.5-1.2-1.5-1.8-1.61.8-1.81.7-1.7
Patch foraging total patch changes 12 sec0.60.81.51.0-0.90.10.9-0.1-0.9-0.8-1.11.0-1.01.2-1.0
Patch foraging total patch changes 18 sec2.53.86.11.8-1.81.21.8-1.2-1.9-1.9-2.12.2-2.22.5-2.4
Patch foraging total patch changes 24 sec1.93.33.81.9-1.91.41.9-1.4-1.9-1.7-1.91.9-1.91.8-1.8
Patch foraging total patch changes 6 sec0.20.31.70.3-0.30.00.2-0.1-0.4-0.5-0.60.6-0.61.3-0.5
Patch foraging time to switch 0 sec0.30.51.6-0.60.6-0.4-0.60.40.70.90.8-0.80.8-1.30.6
Patch foraging water rate 0 sec0.20.50.80.7-0.70.10.7-0.1-0.7-0.8-0.70.9-0.90.7-0.7
Patch foraging water rate 12 sec0.20.40.60.8-0.80.70.8-0.7-0.7-0.7-0.60.6-0.60.3-0.4
Patch foraging water rate 18 sec0.30.51.50.5-0.61.20.6-1.2-0.5-0.8-0.30.5-0.5-0.10.0
Patch foraging water rate 24 sec1.01.31.91.1-1.11.31.1-1.3-1.1-1.3-1.01.4-1.40.7-0.9
Patch foraging water rate 6 sec0.50.72.70.8-0.80.40.8-0.3-0.8-0.7-0.90.7-0.71.7-0.4
Seeking ratio, delayed vs. immediate footshock0.91.22.1-1.51.4-0.5-1.40.51.30.61.2-1.01.0-1.00.8
Distance traveled before self-admin0.20.21.9-0.40.30.1-0.2-0.10.40.10.60.1-0.1-1.40.3
Distance traveled after self-admin0.40.51.1-0.40.5-0.9-0.40.90.61.00.6-0.80.8-0.40.7
Extensor digitorum longus weight0.10.62.2-0.70.6-0.3-0.60.40.70.60.9-0.70.7-1.50.7
Bone: elastic displacement0.10.10.10.3-0.3-0.30.30.3-0.2-0.3-0.10.3-0.3-0.3-0.2
Bone: elastic work0.30.40.80.8-0.80.20.9-0.2-0.7-0.6-0.60.7-0.70.9-0.3
Bone: endosteal estimation0.10.30.60.5-0.50.70.4-0.8-0.5-0.5-0.60.5-0.50.7-0.6
Bone: endosteal perimeter0.91.92.4-1.51.4-1.0-1.41.01.41.51.5-1.51.5-1.11.4
Epididymis fat weight0.61.92.81.1-1.21.71.2-1.7-1.2-1.6-1.21.7-1.70.7-1.4
Delta time in closed arm before/after self-admin0.20.20.3-0.60.50.3-0.6-0.30.5-0.00.5-0.20.2-0.20.4
Delta time in open arm before/after self-admin0.20.20.60.5-0.4-0.60.40.6-0.40.2-0.5-0.10.10.8-0.2
Diff in mean of infusions in LGA sessions0.10.11.20.1-0.10.10.2-0.10.1-0.10.20.0-0.0-1.10.1
Delay discount exponential model param1.82.02.71.6-1.61.41.6-1.4-1.5-1.5-1.41.3-1.30.7-1.3
Extinction: sum of active levers before priming0.10.20.40.0-0.10.5-0.0-0.5-0.2-0.6-0.20.5-0.50.2-0.6
Active lever presses in extinction session 60.50.51.00.4-0.50.90.4-0.9-0.5-0.8-0.51.0-1.00.2-0.9
Bone: final force1.01.62.11.4-1.41.31.4-1.3-1.3-1.3-1.21.2-1.21.3-0.9
Bone: final moment1.22.02.61.5-1.61.61.6-1.5-1.5-1.4-1.31.3-1.31.2-1.1
Food consumed during 24 hour testing period1.52.03.01.5-1.51.71.5-1.7-1.5-1.4-1.31.4-1.40.6-1.3
Glucose1.01.52.71.2-1.11.41.1-1.4-1.2-1.1-1.31.1-1.11.7-1.1
Heart weight1.93.04.31.8-1.91.62.0-1.6-1.7-2.1-1.51.9-1.9-0.0-1.7
Delay discount hyperbolic model param2.12.33.01.7-1.71.51.7-1.5-1.6-1.6-1.51.5-1.50.9-1.4
Intermittent access intake day 1-15 change0.61.34.0-1.01.0-1.2-0.91.21.11.21.2-0.90.9-2.00.8
Intermittent access intake escalation0.91.95.1-1.21.2-1.4-1.11.41.31.41.4-1.21.2-2.31.0
Intermittent access intake escalation 20.50.63.8-0.30.3-0.9-0.20.90.40.70.7-0.50.5-2.00.3
Intermitt. access day 1 inactive lever presses0.00.10.8-0.30.3-0.0-0.30.00.30.10.5-0.30.3-0.90.4
Intermitt. access day 15 inactive lever presses1.22.53.6-1.51.4-1.4-1.31.41.61.51.7-1.61.6-1.81.9
Intermitt. access escalation Index0.20.31.4-0.10.00.6-0.1-0.6-0.1-0.6-0.30.6-0.61.2-0.2
Intermittent access day 1 total infusions0.10.20.3-0.50.5-0.4-0.40.40.50.40.5-0.40.4-0.50.3
Intermittent access day 15 total infusions1.21.84.1-1.31.3-1.3-1.21.31.31.41.5-1.21.2-2.01.0
Intermittent access terminal intake (last 3 days)0.91.22.5-1.01.0-1.0-1.01.01.11.21.2-1.01.0-1.60.7
Intermittent access total infusions1.21.43.1-1.21.2-1.1-1.11.11.21.21.3-1.01.0-1.80.9
Intermittent access day 1 locomotion0.00.00.10.3-0.2-0.10.20.1-0.30.2-0.30.1-0.10.2-0.3
Intermittent access day 15 total locomotion0.30.51.0-0.50.6-0.9-0.60.90.61.00.6-0.80.8-0.90.4
Intermittent access total locomotion0.81.01.5-0.90.9-1.1-1.01.10.91.20.9-1.01.0-0.90.6
Intermittent access standard deviation0.20.52.70.1-0.0-0.90.20.90.20.80.4-0.50.5-1.70.3
Left kidney weight0.83.55.91.8-1.82.41.8-2.4-1.9-1.9-1.81.8-1.81.0-1.7
Right kidney weight0.52.45.31.3-1.42.31.3-2.3-1.4-1.5-1.31.4-1.40.3-1.5
Cocaine induced anxiety0.00.00.10.1-0.1-0.20.20.2-0.10.2-0.0-0.00.0-0.3-0.1
Post-drug Anxiety0.20.20.5-0.20.2-0.7-0.20.70.20.50.2-0.40.4-0.40.2
Baseline Anxiety0.00.10.1-0.30.3-0.2-0.30.20.2-0.00.2-0.30.30.00.2
Tail length4.316.718.64.3-4.33.84.2-3.8-4.3-4.1-4.34.1-4.13.6-4.1
Length with tail8.637.542.06.4-6.46.26.5-6.2-6.3-6.3-6.16.5-6.53.9-5.9
Length without tail8.427.031.65.3-5.45.65.4-5.6-5.2-5.6-4.95.6-5.62.5-4.9
Times rat made contact with spout0.30.40.50.6-0.60.70.6-0.7-0.6-0.6-0.50.6-0.6-0.0-0.7
Lifetime Intake1.41.72.5-1.31.3-1.3-1.31.31.31.51.4-1.21.2-1.61.1
Liver weight, left0.50.91.10.9-0.90.80.8-0.8-0.9-1.0-1.01.0-1.01.0-1.0
Liver weight, right1.62.83.81.7-1.71.81.6-1.8-1.7-1.9-1.71.7-1.71.0-1.6
Locomotor activity5.48.410.63.3-3.22.53.3-2.5-3.2-2.8-3.12.8-2.82.3-2.9
Locomotor testing distance4.17.510.13.2-3.12.53.2-2.5-3.1-2.4-2.92.5-2.51.9-2.7
Locomotor testing rearing0.20.30.70.7-0.70.40.7-0.4-0.6-0.6-0.50.5-0.5-0.2-0.8
Locomotion in novel chamber0.20.20.5-0.30.3-0.6-0.30.60.40.30.5-0.40.4-0.70.2
Locomotion in novel chamber post-restriction0.40.71.70.8-0.80.30.8-0.3-0.9-0.9-1.00.7-0.71.3-0.9
Fecal boli incidents, locomotor time 10.40.61.20.7-0.70.80.7-0.8-0.7-1.1-0.70.9-0.90.5-0.6
Change in fecal boli incidents, locomotor task0.00.00.1-0.00.0-0.1-0.00.1-0.0-0.0-0.0-0.00.00.30.0
Time >=10cm from walls, locomotor time 10.20.20.3-0.50.5-0.1-0.50.10.40.40.3-0.40.40.50.5
Bouts of movement, locomotor time 10.00.00.00.1-0.1-0.20.10.2-0.1-0.0-0.10.1-0.10.1-0.1
Total resting periods, locomotor time 10.00.00.00.1-0.1-0.10.10.1-0.1-0.1-0.10.2-0.20.1-0.1
Rest time, locomotor task time 10.30.30.8-0.80.7-0.4-0.70.40.70.20.7-0.30.3-0.90.3
Distance moved, locomotor task time 10.71.11.71.3-1.30.91.3-0.9-1.2-0.8-1.11.0-1.01.0-0.8
Vertical activity count, locomotor time 10.20.50.90.9-0.80.50.9-0.5-0.8-0.5-0.80.6-0.61.0-0.4
Time >=10cm from walls, locomotor time 21.21.72.21.2-1.31.31.2-1.3-1.3-1.5-1.31.5-1.51.4-1.0
Bouts of movement, locomotor time 20.00.10.20.3-0.30.10.3-0.1-0.2-0.2-0.10.5-0.5-0.2-0.1
Total resting periods, locomotor time 20.00.00.10.0-0.1-0.10.10.1-0.0-0.10.00.3-0.3-0.20.0
Rest time, locomotor task time 20.00.00.1-0.10.1-0.3-0.20.30.1-0.20.00.2-0.20.4-0.1
Distance moved, locomotor task time 20.50.60.90.9-0.90.81.0-0.8-0.9-0.5-0.70.7-0.70.2-0.6
Vertical activity count, locomotor time 20.00.00.10.1-0.10.00.1-0.0-0.10.3-0.0-0.20.2-0.30.1
Light reinforcement 10.30.81.01.0-1.00.90.9-0.9-1.0-0.7-1.00.8-0.81.0-0.6
Light reinforcement 20.10.20.6-0.40.40.5-0.5-0.50.20.30.2-0.40.40.70.8
Bone: marrow area0.20.30.60.5-0.50.80.5-0.8-0.5-0.5-0.60.5-0.50.8-0.6
Bone: maximum diameter0.40.70.8-0.80.7-0.9-0.70.90.80.90.9-0.80.8-0.70.9
Bone: maximum force0.81.52.01.2-1.21.31.3-1.3-1.2-1.2-1.21.1-1.11.4-1.0
Bone: maximum moment1.01.72.21.3-1.31.51.4-1.5-1.3-1.2-1.21.2-1.21.3-1.0
Mean time between licks in bursts0.61.62.4-1.21.2-1.2-1.11.21.21.31.4-1.31.3-1.61.1
Mean num. licks in bursts0.50.81.50.8-0.70.90.7-0.9-0.8-0.8-0.90.8-0.81.2-0.8
Cd content in liver0.10.10.1-0.30.3-0.3-0.30.30.20.30.2-0.30.3-0.30.1
Co content in liver0.91.11.7-1.11.0-0.8-1.00.81.10.91.2-1.11.1-1.31.0
Cu content in liver4.04.75.62.2-2.22.12.2-2.1-2.2-2.1-2.22.2-2.22.4-1.9
Fe content in liver1.11.41.81.1-1.11.11.2-1.1-1.1-1.3-1.11.3-1.31.1-1.3
K content in liver0.30.32.50.3-0.2-0.00.20.0-0.3-0.1-0.40.3-0.31.60.2
Mg content in liver1.01.02.5-0.91.0-1.0-1.01.00.91.10.8-1.11.10.61.6
Mn content in liver0.20.32.60.1-0.0-0.2-0.00.3-0.10.1-0.3-0.10.11.60.5
Na content in liver0.40.51.30.6-0.5-0.50.50.5-0.5-0.6-0.60.8-0.81.1-0.7
Rb content in liver0.80.91.90.9-0.90.91.0-0.9-0.8-1.2-0.71.1-1.10.0-1.4
Se content in liver0.10.10.70.00.0-0.1-0.00.10.00.1-0.1-0.00.00.80.4
Sr content in liver0.20.20.8-0.00.10.4-0.1-0.3-0.00.4-0.1-0.40.40.80.9
Zn content in liver2.62.83.91.6-1.62.01.6-2.0-1.7-1.6-1.71.5-1.52.0-1.4
Bone: minimum diameter0.30.50.7-0.80.7-0.6-0.70.60.70.70.8-0.80.8-0.70.8
Time in familiar zone, hab. session 11.11.12.9-1.01.0-1.1-0.91.11.10.91.2-0.80.8-1.70.6
Time in novel zone, hab. session 10.30.30.70.7-0.70.80.6-0.8-0.6-0.2-0.60.2-0.20.1-0.3
Total zone transitions, hab. session 10.70.92.00.9-0.91.30.8-1.3-1.0-0.5-1.10.5-0.51.4-0.5
Total locomotion distance, hab. session 10.30.40.90.5-0.50.90.5-0.9-0.6-0.5-0.60.4-0.40.9-0.3
Locomotion velocity, hab. session 10.30.52.10.5-0.50.80.5-0.8-0.6-0.5-0.70.5-0.51.4-0.3
Time in familiar zone, hab. session 20.50.51.0-0.60.6-1.0-0.61.00.70.60.8-0.50.5-0.80.6
Time in novel zone, hab. session 20.10.10.40.2-0.20.60.2-0.6-0.3-0.1-0.20.1-0.1-0.2-0.4
Total zone transitions, hab. session 20.20.20.70.3-0.30.90.3-0.8-0.40.0-0.40.0-0.00.50.2
Total locomotion distance, hab. session 20.30.41.60.5-0.50.70.4-0.7-0.5-0.5-0.60.5-0.51.3-0.2
Locomotion velocity, hab. session 20.20.31.80.4-0.30.50.3-0.5-0.4-0.3-0.50.3-0.31.30.0
Novel to familiar place preference ratio1.31.44.90.9-0.90.90.8-1.0-1.1-1.2-1.31.1-1.12.2-1.2
Novelty place preference1.31.45.10.9-0.90.90.7-0.9-1.1-1.1-1.31.1-1.12.3-1.2
Time in novel zone, NPP test1.51.74.11.1-1.01.10.9-1.1-1.2-1.3-1.41.3-1.32.0-1.4
Total zone transitions, NPP test2.43.44.91.9-1.82.21.8-2.2-2.0-1.5-2.01.5-1.52.2-1.2
Total locomotion distance, NPP test1.01.31.81.1-1.11.31.1-1.3-1.1-1.1-1.21.2-1.21.3-0.7
Locomotion velocity, NPP test1.11.53.21.2-1.11.41.1-1.4-1.2-1.1-1.31.2-1.21.8-0.7
Intraocular pressure1.01.52.61.1-1.21.11.1-1.1-1.2-1.3-1.11.5-1.50.3-1.6
Delta distance traveled before/after self-admin0.20.21.10.00.0-0.5-0.10.5-0.00.4-0.2-0.50.51.10.3
Delta ambulatory time before/after self-admin0.50.62.70.9-0.80.40.8-0.4-0.9-0.3-1.00.2-0.21.6-0.5
Parametrial fat weight0.51.12.91.2-1.10.61.1-0.6-1.1-1.0-1.21.0-1.01.7-0.5
Pavlov. Cond. lever latency4.05.06.32.3-2.42.42.4-2.4-2.3-2.1-2.22.2-2.20.9-2.5
Pavlov. Cond. magazine entry latency7.59.611.1-3.13.1-3.3-3.13.33.23.23.1-3.23.2-1.93.2
Pavlov. Cond. change in total contacts1.41.52.6-1.31.3-1.6-1.31.61.31.01.2-1.11.1-0.21.1
Pavlov. Cond. index score6.27.99.3-2.82.9-3.0-2.83.12.92.82.8-2.92.9-1.62.9
Pavlov. Cond. latency score5.97.58.7-2.82.8-2.9-2.82.92.82.72.7-2.82.8-1.42.9
Pavlov. Cond. lever contacts2.42.94.0-1.81.8-1.7-1.81.71.81.71.7-1.81.8-0.52.0
Pavlov. Cond. magazine entry number7.59.511.43.1-3.13.43.1-3.4-3.1-3.1-3.13.1-3.12.2-3.0
Pavlov. Cond. intertrial magazine entries0.50.50.80.7-0.70.90.8-0.9-0.7-0.6-0.70.7-0.70.3-0.8
Pavlov. Cond. lever-magazine prob. diff.5.77.08.4-2.62.7-2.9-2.62.92.72.62.7-2.72.7-1.62.8
Pavlov. Cond. response bias6.78.39.5-2.92.9-3.1-2.93.12.92.92.9-3.03.0-2.03.0
Pavlov. Cond. lever latency0.71.01.2-1.11.1-0.7-1.10.71.11.01.1-1.01.0-1.10.7
Pavlov. Cond. magazine entry latency0.10.10.4-0.20.3-0.6-0.30.60.30.30.2-0.30.30.10.5
Pavlov. Cond. change in total contacts2.23.64.32.1-2.01.62.0-1.6-2.0-2.0-1.92.0-2.01.6-1.7
Pavlov. Cond. index score0.20.30.60.6-0.60.10.6-0.1-0.6-0.5-0.60.5-0.50.7-0.2
Pavlov. Cond. latency score0.10.20.50.5-0.50.00.5-0.0-0.4-0.4-0.50.4-0.40.7-0.0
Pavlov. Cond. lever contacts1.01.31.91.2-1.20.81.2-0.8-1.2-1.2-1.31.2-1.21.4-0.9
Pavlov. Cond. magazine entry number0.10.10.40.3-0.30.60.3-0.6-0.3-0.3-0.30.3-0.3-0.1-0.5
Pavlov. Cond. intertrial magazine entries0.50.70.8-0.90.9-0.8-0.90.80.90.80.9-0.70.7-0.90.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.40.6-0.50.10.5-0.1-0.5-0.4-0.50.4-0.40.7-0.1
Pavlov. Cond. response bias0.10.20.50.5-0.50.10.5-0.1-0.4-0.4-0.50.4-0.40.7-0.1
Time in closed arm before self-admin1.01.32.31.2-1.21.11.3-1.1-1.2-0.9-1.11.1-1.10.2-1.5
Time in closed arm after self-admin0.20.20.9-0.20.20.6-0.2-0.60.20.00.30.1-0.1-1.0-0.2
Time in open arm before self-admin0.80.91.3-1.11.1-0.3-1.10.31.00.61.1-1.01.0-1.11.0
Time in open arm after self-admin0.70.71.8-0.60.7-1.3-0.71.30.50.90.3-0.90.91.00.5
Bone: periosteal estimation0.00.10.20.2-0.30.40.3-0.4-0.2-0.3-0.20.2-0.20.5-0.2
Bone: periosteal perimeter0.71.31.5-1.21.2-1.1-1.21.11.21.21.2-1.21.2-0.51.2
Bone: post-yield work0.10.10.60.2-0.20.80.2-0.8-0.2-0.1-0.20.1-0.10.1-0.1
Progressive ratio test 1 active lever presses0.00.00.20.1-0.10.00.0-0.0-0.20.1-0.2-0.10.10.4-0.4
Progressive ratio test 1 breakpoint0.00.00.20.0-0.00.1-0.0-0.1-0.10.1-0.2-0.10.10.5-0.3
Progressive ratio test 1 inactive lever presses0.60.82.5-0.60.6-1.1-0.51.10.71.10.8-0.90.9-1.60.5
Progressive ratio test 2 active lever presses2.22.53.6-1.51.5-1.6-1.51.61.51.71.6-1.61.6-1.91.3
Progressive ratio test 2 breakpoint2.32.63.7-1.51.5-1.6-1.51.61.61.71.7-1.61.6-1.91.3
Progressive ratio test 2 inactive lever presses2.23.68.5-1.71.6-1.7-1.51.71.81.92.1-2.02.0-2.91.6
Incentive Sensitization - Responses2.33.36.5-1.71.6-1.7-1.61.71.81.61.9-1.81.8-2.61.7
Incentive Sensitization - Breakpoint2.63.36.5-1.71.7-1.7-1.61.71.81.62.0-1.81.8-2.61.7
Sum of active levers in priming session hrs 5-60.10.10.3-0.20.2-0.4-0.30.40.10.4-0.1-0.20.20.5-0.1
Progressive ratio2.64.04.72.0-2.01.81.9-1.8-2.0-2.2-2.12.1-2.12.1-2.2
Food seeking constrained by brief footshock0.70.91.9-1.11.1-0.3-1.10.31.10.71.1-0.80.8-1.40.8
Seeking ratio, punishment vs. effort4.05.78.4-2.52.5-1.8-2.41.82.52.32.7-2.32.3-2.92.5
Retroperitoneal fat weight1.35.76.82.5-2.52.12.5-2.1-2.5-2.6-2.52.5-2.52.2-2.0
Reaction time number correct0.20.40.9-0.60.6-0.7-0.50.70.60.80.7-0.60.6-1.00.3
Reaction time mean minus median0.00.00.10.2-0.20.10.1-0.1-0.20.1-0.2-0.20.20.00.2
Reaction time mean minus median AUC0.10.20.30.5-0.50.60.5-0.5-0.6-0.5-0.60.3-0.30.3-0.4
Reaction time num false alarms0.10.20.3-0.50.5-0.5-0.50.50.40.40.4-0.30.3-0.40.0
Reaction time num false alarms AUC0.00.00.1-0.20.2-0.3-0.30.30.10.20.1-0.10.1-0.1-0.2
Reaction time trials correct on left0.20.40.9-0.60.6-0.7-0.50.70.60.80.7-0.60.6-1.00.3
Reaction time trials on left0.20.41.0-0.60.6-0.7-0.60.70.60.90.7-0.60.6-1.00.3
Reaction time mean0.00.00.00.1-0.1-0.10.10.1-0.10.0-0.1-0.00.00.1-0.1
Reaction time mean AUC0.00.00.00.0-0.00.0-0.0-0.0-0.1-0.0-0.1-0.10.10.1-0.1
Median of all reaction times0.00.00.0-0.00.0-0.2-0.00.20.00.0-0.00.0-0.00.0-0.1
Reaction time omissions0.20.30.7-0.50.5-0.7-0.50.70.50.50.5-0.70.7-0.80.1
Reaction time false alarm rate0.00.00.0-0.10.1-0.1-0.10.10.0-0.1-0.00.0-0.00.2-0.2
Reaction time premature initiation rate1.21.62.71.5-1.41.01.4-1.0-1.4-1.1-1.51.0-1.01.6-0.8
Reaction time premature initiations0.40.71.11.1-1.00.61.0-0.6-1.0-0.5-1.00.6-0.61.0-0.4
Std. dev. reaction times0.10.10.20.4-0.30.20.3-0.2-0.4-0.3-0.50.2-0.20.4-0.4
Reaction time trials completed0.20.41.0-0.60.6-0.7-0.60.70.60.90.7-0.60.6-1.00.3
Reaction time trials AUC0.30.61.3-0.70.7-0.8-0.70.80.70.90.8-0.60.6-1.20.4
Run reversals in cocaine runway, females1.11.11.5-1.11.1-0.8-1.10.81.11.11.2-1.01.0-1.11.2
Run reversals in cocaine runway, males0.20.20.50.7-0.6-0.50.70.5-0.50.3-0.4-0.20.2-0.10.1
Latency to leave start box in cocaine runway0.10.10.20.4-0.3-0.50.30.5-0.30.0-0.3-0.20.20.30.0
Latency to leave start box in cocaine runway, F0.30.30.90.9-0.9-0.21.00.2-0.7-0.3-0.60.3-0.3-0.1-0.4
Latency to leave start box in cocaine runway, M0.90.81.2-1.01.1-0.9-1.10.90.90.70.8-1.01.00.01.0
Std. dev. time between licks in bursts2.83.96.5-1.91.9-1.7-1.81.72.01.92.2-1.91.9-2.51.9
Total sessions with >9 infusions0.60.72.6-0.70.7-0.5-0.70.50.70.80.9-0.70.7-1.60.7
Short access day 1 total inactive lever presses2.22.93.4-1.81.8-1.5-1.81.51.81.71.8-1.71.7-1.81.5
Short access day 10 total inactive lever presses0.10.21.20.3-0.30.30.4-0.3-0.2-0.20.00.1-0.1-1.10.0
Short access day 1 total infusions2.63.43.8-1.91.9-1.8-1.91.81.92.01.9-1.81.8-1.61.8
Short access day 10 total infusions1.21.52.3-1.51.5-0.8-1.50.81.41.21.4-1.11.1-1.11.2
Short access total infusions2.43.13.7-1.91.9-1.6-1.91.61.81.91.8-1.71.7-1.61.6
Short access day 1 locomotion0.50.61.4-0.80.8-0.4-0.80.40.80.90.9-0.50.5-1.20.7
Short access day 10 total locomotion0.10.20.60.2-0.20.40.1-0.4-0.3-0.3-0.40.5-0.50.8-0.4
Short access total locomotion0.00.00.1-0.20.2-0.1-0.30.10.10.40.1-0.00.0-0.1-0.0
One hour access (0.3 mA shock)0.30.30.5-0.60.6-0.6-0.60.60.50.70.5-0.70.7-0.70.0
Compulsive drug intake0.50.61.0-0.90.9-0.6-1.00.60.80.80.7-0.70.70.10.7
One hour access (shock baseline)0.30.51.7-0.50.5-0.7-0.40.70.50.90.6-0.70.7-1.30.2
Social response proportion0.10.10.20.3-0.3-0.00.30.0-0.3-0.1-0.40.1-0.10.5-0.3
Social responses0.30.41.80.6-0.60.60.5-0.6-0.7-0.5-0.70.5-0.51.3-0.4
Social time1.41.95.2-0.80.8-1.0-0.71.01.01.61.3-1.71.7-2.31.4
Soleus weight4.312.714.63.7-3.73.83.7-3.8-3.7-3.6-3.63.5-3.52.9-3.2
Bone: stiffness0.20.30.80.5-0.50.60.5-0.7-0.5-0.5-0.60.5-0.50.9-0.5
Tibialis anterior weight0.10.30.90.3-0.40.90.4-0.9-0.3-0.4-0.10.3-0.3-0.6-0.2
Time to tail flick, vehicle, before self-admin2.22.32.81.4-1.51.61.4-1.6-1.4-1.7-1.41.7-1.70.7-1.7
Time to tail flick, vehicle, after self-admin0.10.10.30.3-0.2-0.60.30.6-0.20.2-0.2-0.30.30.50.1
Time to tail flick, test, before self-admin0.00.00.1-0.30.30.2-0.4-0.20.10.10.1-0.10.10.30.3
Time to tail flick, test, after self-admin0.10.10.2-0.40.3-0.2-0.30.20.40.30.4-0.30.3-0.50.3
Delta time to tail flick, vehicle, before/after SA1.21.12.2-0.80.8-1.5-0.81.50.91.20.8-1.21.20.01.2
Delta time to tail flick, test, before/after SA0.00.00.0-0.20.1-0.1-0.10.10.20.00.20.1-0.1-0.1-0.2
Tibia length6.718.621.04.5-4.54.64.5-4.6-4.5-4.2-4.44.2-4.24.2-3.5
Ambulatory time before self-admin0.30.52.5-0.70.6-0.1-0.60.10.80.20.9-0.10.1-1.60.5
Ambulatory time after self-admin0.10.10.2-0.10.2-0.3-0.20.30.20.40.2-0.40.40.20.3
Bone: tissue strength3.33.33.91.9-1.91.72.0-1.7-1.8-1.9-1.72.0-2.01.5-1.6
Total heroin consumption1.31.52.61.6-1.50.81.6-0.8-1.4-1.2-1.31.1-1.10.7-1.1
Bone: trabecular number0.61.01.5-1.01.1-1.2-1.11.21.00.90.8-1.01.0-0.20.7
Bone: trabecular spacing1.41.82.41.4-1.51.61.5-1.6-1.4-1.3-1.21.4-1.40.5-1.1
Bone: trabecular thickness0.20.22.40.1-0.0-0.0-0.00.1-0.1-0.2-0.40.1-0.11.50.1
Bone: trabecular tissue density0.20.30.70.7-0.60.60.6-0.6-0.6-0.4-0.70.5-0.50.8-0.4
Water consumed over 24 hours0.10.10.70.2-0.30.60.3-0.6-0.1-0.10.10.1-0.1-0.80.1
Number of responses in last shaping day0.30.32.9-0.30.20.2-0.1-0.20.4-0.20.60.1-0.1-1.70.2