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Intermittent access terminal intake (last 3 days)

Intermittent access terminal intake (last 3 days)

Tags: Behavior · Intermittent access · Cocaine

Project: p50_paul_meyer_2020

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr7	92127461	93523291	1	1	7.49e-10	3.95e-02	7.82e-02	Nsmce2
2	chr8	41432021	42517271	1	1	4.80e-15	5.58e-02	2.38e-04	Foxred1
3	chr9	83390749	84777604	1	1	0.00e+00	7.98e-02	1.00e+00	Retreg2
4	chr13	84702566	86100919	1	1	4.92e-09	1.79e-01	1.44e-09	Olfml2b

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	220.26	4	1	25	-1	1.53e-03	Foxred1 Nsmce2 Olfml2b Retreg2
BMI without tail	28623.88	2	1	25	0	1.00e+00	Olfml2b Retreg2
Body weight	3.24	3	0	0	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Epididymis fat weight	36276.19	1	1	25	0	1.00e+00	Retreg2
Glucose	273.2	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Heart weight	3065.65	1	1	25	0	1.00e+00	Retreg2
Left kidney weight	18350.37	3	1	25	0	1.00e+00	Foxred1 Olfml2b Retreg2
Right kidney weight	20201.04	2	1	25	0	1.00e+00	Foxred1 Retreg2
Tail length	28919.24	1	1	25	0	1.00e+00	Retreg2
Length with tail	743.15	2	1	25	0	1.00e+00	Foxred1 Retreg2
Length without tail	47233.74	1	1	25	0	1.00e+00	Retreg2
Liver weight, left	3487.23	1	1	25	0	1.00e+00	Retreg2
Liver weight, right	47.7	1	1	25	0	1.00e+00	Retreg2
Parametrial fat weight	63.1	3	1	25	0	1.00e+00	Foxred1 Nsmce2 Retreg2
Retroperitoneal fat weight	1970.37	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Intraocular pressure	10386.52	1	1	25	0	1.00e+00	Retreg2
Extensor digitorum longus weight	539.72	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Soleus weight	13.4	2	1	25	0	1.00e+00	Olfml2b Retreg2
Tibialis anterior weight	580.53	2	1	25	0	1.00e+00	Olfml2b Retreg2
Tibia length	767.35	1	1	25	0	1.00e+00	Retreg2
Number of licking bursts	67424.86	1	1	25	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	35509.41	1	1	25	0	1.00e+00	Retreg2
Times rat made contact with spout	71.66	1	1	25	0	1.00e+00	Retreg2
Mean time between licks in bursts	111630.35	1	1	25	0	1.00e+00	Retreg2
Mean num. licks in bursts	56750.08	1	1	25	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	29750.31	1	1	25	0	1.00e+00	Retreg2
Water consumed over 24 hours	34168.6	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	50128.13	1	1	25	0	1.00e+00	Retreg2
Indifference point function ln k	27827.08	2	1	25	0	1.00e+00	Olfml2b Retreg2
Indifference point function log k	27827.08	2	1	25	0	1.00e+00	Olfml2b Retreg2
Patch foraging total patch changes 0 sec	20975.34	2	1	25	0	1.00e+00	Foxred1 Retreg2
Patch foraging total patch changes 12 sec	1154.4	2	1	25	0	1.00e+00	Foxred1 Retreg2
Patch foraging total patch changes 18 sec	40454.12	1	1	25	0	1.00e+00	Retreg2
Patch foraging total patch changes 24 sec	74801.17	1	1	25	0	1.00e+00	Retreg2
Patch foraging total patch changes 6 sec	7787.09	1	1	25	0	1.00e+00	Retreg2
Patch foraging time to switch 0 sec	33248.73	2	1	25	0	1.00e+00	Olfml2b Retreg2
Patch foraging water rate 0 sec	20144.84	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Patch foraging water rate 12 sec	70639.93	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	33728.57	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 24 sec	519.06	2	1	25	0	1.00e+00	Olfml2b Retreg2
Patch foraging water rate 6 sec	837.86	1	1	25	0	1.00e+00	Retreg2
Locomotor activity	8.9	1	0	0	0	1.00e+00	Foxred1
Locomotor testing distance	13835.96	2	1	25	0	1.00e+00	Foxred1 Retreg2
Locomotor testing rearing	31701.62	2	1	25	0	1.00e+00	Foxred1 Retreg2
Light reinforcement 1	66311.75	1	1	25	0	1.00e+00	Retreg2
Light reinforcement 2	18371.7	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time number correct	31740.61	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time mean minus median	59978.01	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time mean minus median AUC	61996.05	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time num false alarms	15357.42	1	1	25	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	35016.83	1	1	25	0	1.00e+00	Retreg2
Reaction time trials correct on left	31740.61	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time trials on left	30446.63	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time mean	29724.21	1	1	25	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	25	0	1.00e+00	Retreg2
Median of all reaction times	7893.84	1	1	25	0	1.00e+00	Retreg2
Reaction time omissions	8364.84	1	1	25	0	1.00e+00	Retreg2
Reaction time false alarm rate	210.6	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiation rate	4876.72	2	2	50	0	1.00e+00	Nsmce2 Retreg2
Reaction time premature initiations	26876.55	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Std. dev. reaction times	30435.24	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time trials completed	30446.63	2	1	25	0	1.00e+00	Olfml2b Retreg2
Reaction time trials AUC	31069.96	2	1	25	0	1.00e+00	Olfml2b Retreg2
Social response proportion	8777.03	1	1	25	0	1.00e+00	Retreg2
Social responses	639.43	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Social time	11650.06	1	1	25	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	25	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	25	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	28713.86	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	1153.32	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	3863.86	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	39811.91	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	12744.53	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	34989.79	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	25	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	33602.2	3	1	25	0	1.00e+00	Foxred1 Olfml2b Retreg2
Conditioned reinforcement - inactives	16223.79	4	1	25	1	1.15e-03	Foxred1 Nsmce2 Olfml2b Retreg2
Conditioned locomotion	3452.02	3	1	25	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermittent access intake day 1-15 change	42639.27	3	2	50	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermittent access intake escalation	42052.19	3	2	50	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermittent access intake escalation 2	12099.58	3	2	50	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermitt. access day 1 inactive lever presses	90307.7	2	1	25	0	1.00e+00	Olfml2b Retreg2
Intermitt. access day 15 inactive lever presses	41221.03	3	3	75	0	1.00e+00	Foxred1 Olfml2b Retreg2
Intermitt. access escalation Index	31107.43	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Intermittent access day 1 total infusions	16536.51	4	1	25	-1	2.88e-03	Foxred1 Nsmce2 Olfml2b Retreg2
Intermittent access day 15 total infusions	12205.42	4	3	75	1	2.56e-04	Foxred1 Nsmce2 Olfml2b Retreg2
Intermittent access total infusions	59.01	4	1	25	-0.79	2.09e-01	Foxred1 Nsmce2 Olfml2b Retreg2
Intermittent access day 1 locomotion	8750.94	4	2	50	-1	3.02e-03	Foxred1 Nsmce2 Olfml2b Retreg2
Intermittent access day 15 total locomotion	28520.6	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Intermittent access total locomotion	45.74	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Intermittent access standard deviation	28496.63	4	1	25	1	1.59e-03	Foxred1 Nsmce2 Olfml2b Retreg2
Cocaine induced anxiety	34556.04	2	1	25	0	1.00e+00	Foxred1 Retreg2
Post-drug Anxiety	4753.56	1	1	25	0	1.00e+00	Retreg2
Baseline Anxiety	16757.7	2	1	25	0	1.00e+00	Foxred1 Retreg2
Lifetime Intake	425.17	4	1	25	-0.97	3.23e-02	Foxred1 Nsmce2 Olfml2b Retreg2
Incentive Sensitization - Responses	35678.66	2	1	25	0	1.00e+00	Olfml2b Retreg2
Incentive Sensitization - Breakpoint	18430.63	3	1	25	0	1.00e+00	Foxred1 Olfml2b Retreg2
Progressive ratio test 1 active lever presses	10665.29	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Progressive ratio test 1 breakpoint	10102.62	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Progressive ratio test 1 inactive lever presses	31107.65	2	1	25	0	1.00e+00	Foxred1 Retreg2
Progressive ratio test 2 active lever presses	5094.28	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Progressive ratio test 2 breakpoint	2853.97	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Progressive ratio test 2 inactive lever presses	24176.22	3	1	25	0	1.00e+00	Foxred1 Nsmce2 Retreg2
Total sessions with >9 infusions	661.21	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Short access day 1 total inactive lever presses	19711.07	2	1	25	0	1.00e+00	Foxred1 Retreg2
Short access day 10 total inactive lever presses	69426.3	2	1	25	0	1.00e+00	Olfml2b Retreg2
Short access day 1 total infusions	12799.92	3	1	25	0	1.00e+00	Foxred1 Nsmce2 Retreg2
Short access day 10 total infusions	7573.5	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Short access total infusions	4396.46	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Short access day 1 locomotion	12410.8	2	1	25	0	1.00e+00	Foxred1 Retreg2
Short access day 10 total locomotion	29411.05	3	3	75	0	1.00e+00	Foxred1 Olfml2b Retreg2
Short access total locomotion	6240.52	3	2	50	0	1.00e+00	Foxred1 Olfml2b Retreg2
Compulsive drug intake	6240.53	3	2	50	0	1.00e+00	Foxred1 Nsmce2 Retreg2
One hour access (0.3 mA shock)	1196.43	2	2	50	0	1.00e+00	Foxred1 Retreg2
One hour access (shock baseline)	18336.53	3	1	25	0	1.00e+00	Foxred1 Nsmce2 Retreg2
Number of responses in last shaping day	6813.57	2	1	25	0	1.00e+00	Foxred1 Retreg2
Context. condit. distance diff. score	212.47	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 1	3523.61	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 1	1024.77	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 2	2158.08	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 2	508.11	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 3	507.49	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 7	292.79	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 7	856.72	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	2509.72	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	2115.93	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 8	409.23	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	2042.98	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	957.65	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	4681.39	1	1	25	0	1.00e+00	Retreg2
Incentive salience index mean	3540.72	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	5282.33	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	11168.49	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	429.72	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	6311.49	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	63.93	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	25	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	25	0	1.00e+00	Retreg2
Novelty place preference	14927.56	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, NPP test	10685.62	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, NPP test	1935.62	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	1687.31	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	491.79	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	677.08	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	248.34	2	1	25	0	1.00e+00	Olfml2b Retreg2
Pavlov. Cond. intertrial magazine entries	66.78	2	1	25	0	1.00e+00	Olfml2b Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	25	0	1.00e+00	Retreg2
Bone: apparent density	5461.77	1	1	25	0	1.00e+00	Retreg2
Bone surface	6197.68	1	1	25	0	1.00e+00	Retreg2
Bone volume	8624.75	1	1	25	0	1.00e+00	Retreg2
Bone: connectivity density	1667.52	1	1	25	0	1.00e+00	Retreg2
Bone: cortical apparent density	12020.36	1	1	25	0	1.00e+00	Retreg2
Bone: cortical area	4581.96	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	432.96	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	1113.18	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	374.52	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	1462.17	2	1	25	0	1.00e+00	Olfml2b Retreg2
Bone: cortical tissue density	13002.58	1	1	25	0	1.00e+00	Retreg2
Bone: elastic displacement	7604.03	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	361.86	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal estimation	8913.19	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal perimeter	11863.6	1	1	25	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	25	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	25	0	1.00e+00	Retreg2
Bone: marrow area	9430.07	1	1	25	0	1.00e+00	Retreg2
Bone: maximum diameter	6068.73	1	1	25	0	1.00e+00	Retreg2
Bone: maximum force	8697.09	1	1	25	0	1.00e+00	Retreg2
Bone: maximum moment	5989.29	1	1	25	0	1.00e+00	Retreg2
Bone: minimum diameter	4100.86	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal estimation	9791.57	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal perimeter	11400.25	1	1	25	0	1.00e+00	Retreg2
Bone: post-yield work	13672.98	1	1	25	0	1.00e+00	Retreg2
Bone: stiffness	9032.86	1	1	25	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	5372.17	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Bone: trabecular spacing	7952.12	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular thickness	8476.26	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular tissue density	7279.6	2	1	25	0	1.00e+00	Olfml2b Retreg2
Breakpoint value in progressive ratio session	18805.67	2	1	25	0	1.00e+00	Nsmce2 Retreg2
Distance traveled before self-admin	25274.77	2	1	25	0	1.00e+00	Foxred1 Retreg2
Distance traveled after self-admin	16241.13	2	1	25	0	1.00e+00	Foxred1 Retreg2
Delta time in closed arm before/after self-admin	96.02	3	1	25	0	1.00e+00	Foxred1 Nsmce2 Retreg2
Delta time in open arm before/after self-admin	5049.28	3	1	25	0	1.00e+00	Nsmce2 Olfml2b Retreg2
Diff in mean of infusions in LGA sessions	18332.6	2	1	25	0	1.00e+00	Olfml2b Retreg2
Extinction: sum of active levers before priming	9474.24	3	2	50	0	1.00e+00	Foxred1 Nsmce2 Retreg2
Active lever presses in extinction session 6	258.8	3	1	25	0	1.00e+00	Foxred1 Nsmce2 Retreg2
Delta distance traveled before/after self-admin	1473.99	2	1	25	0	1.00e+00	Foxred1 Retreg2
Delta ambulatory time before/after self-admin	15433.72	2	1	25	0	1.00e+00	Foxred1 Retreg2
Time in closed arm before self-admin	13436.25	2	1	25	0	1.00e+00	Foxred1 Retreg2
Time in closed arm after self-admin	4591.18	1	1	25	0	1.00e+00	Retreg2
Time in open arm before self-admin	8746.25	1	1	25	0	1.00e+00	Retreg2
Time in open arm after self-admin	242.74	2	1	25	0	1.00e+00	Foxred1 Retreg2
Sum of active levers in priming session hrs 5-6	498.46	2	1	25	0	1.00e+00	Olfml2b Retreg2
Time to tail flick, vehicle, before self-admin	6687.73	2	1	25	0	1.00e+00	Foxred1 Retreg2
Time to tail flick, vehicle, after self-admin	21075.15	2	1	25	0	1.00e+00	Foxred1 Retreg2
Time to tail flick, test, before self-admin	4075.07	2	1	25	0	1.00e+00	Foxred1 Retreg2
Time to tail flick, test, after self-admin	704.02	2	1	25	0	1.00e+00	Foxred1 Retreg2
Delta time to tail flick, vehicle, before/after SA	9805.78	1	1	25	0	1.00e+00	Retreg2
Delta time to tail flick, test, before/after SA	15684.59	1	1	25	0	1.00e+00	Retreg2
Ambulatory time before self-admin	39451.03	2	2	50	0	1.00e+00	Foxred1 Retreg2
Ambulatory time after self-admin	13310.23	2	1	25	0	1.00e+00	Olfml2b Retreg2
Total heroin consumption	71.79	4	2	50	0.99	1.19e-02	Foxred1 Nsmce2 Olfml2b Retreg2
Area under the delay curve	12403.68	2	1	25	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 0s delay	1085.91	2	1	25	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 16s delay	10984.31	2	1	25	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 2s delay	80.86	2	1	25	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 24s delay	16225.81	2	1	25	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 4s delay	317.4	2	1	25	0	1.00e+00	Olfml2b Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	25	0	1.00e+00	Retreg2
Delay discount exponential model param	8469.37	2	1	25	0	1.00e+00	Olfml2b Retreg2
Delay discount hyperbolic model param	6148.14	2	1	25	0	1.00e+00	Olfml2b Retreg2
Fecal boli incidents, locomotor time 1	30608.31	2	1	25	0	1.00e+00	Olfml2b Retreg2
Change in fecal boli incidents, locomotor task	5669.94	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 1	6509.4	2	1	25	0	1.00e+00	Olfml2b Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	25	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	25	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	22349.64	1	1	25	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	68821.85	1	1	25	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	35583.9	2	1	25	0	1.00e+00	Olfml2b Retreg2
Bouts of movement, locomotor time 2	27347.4	3	1	25	0	1.00e+00	Foxred1 Olfml2b Retreg2
Total resting periods, locomotor time 2	33018.04	3	1	25	0	1.00e+00	Foxred1 Olfml2b Retreg2
Rest time, locomotor task time 2	12755.16	2	1	25	0	1.00e+00	Olfml2b Retreg2
Distance moved, locomotor task time 2	8477.87	1	1	25	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	25	0	1.00e+00	Retreg2
Weight adjusted by age	70782.25	1	1	25	0	1.00e+00	Retreg2
Seeking ratio, delayed vs. immediate footshock	13445.31	1	1	25	0	1.00e+00	Retreg2
Locomotion in novel chamber	1957.4	2	1	25	0	1.00e+00	Olfml2b Retreg2
Locomotion in novel chamber post-restriction	65422.89	1	1	25	0	1.00e+00	Retreg2
Progressive ratio	67888.93	1	1	25	0	1.00e+00	Retreg2
Food seeking constrained by brief footshock	1875.34	1	1	25	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	41283.25	1	1	25	0	1.00e+00	Retreg2
Run reversals in cocaine runway, females	3145.88	3	1	25	0	1.00e+00	Foxred1 Olfml2b Retreg2
Run reversals in cocaine runway, males	3839.69	2	1	25	0	1.00e+00	Foxred1 Retreg2
Latency to leave start box in cocaine runway	8151.76	2	1	25	0	1.00e+00	Olfml2b Retreg2
Latency to leave start box in cocaine runway, F	3588.2	2	1	25	0	1.00e+00	Olfml2b Retreg2
Latency to leave start box in cocaine runway, M	863.23	2	1	25	0	1.00e+00	Foxred1 Retreg2
Co content in liver	1133.25	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	39.92	1	1	25	0	1.00e+00	Retreg2
Fe content in liver	1344.53	1	1	25	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	3022.31	2	1	25	0	1.00e+00	Olfml2b Retreg2
Mn content in liver	511.02	2	1	25	0	1.00e+00	Olfml2b Retreg2
Na content in liver	2013.06	2	1	25	0	1.00e+00	Olfml2b Retreg2
Rb content in liver	47.17	2	1	25	0	1.00e+00	Olfml2b Retreg2
Se content in liver	7.65	1	0	0	0	1.00e+00	Olfml2b
Sr content in liver	7.22	1	0	0	0	1.00e+00	Olfml2b
Zn content in liver	3745.55	1	1	25	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.14
Adipose	alternative TSS	0	0	1.18
Adipose	gene expression	0	0	1.19
Adipose	isoform ratio	0	0	1.13
Adipose	intron excision ratio	0	0	1.16
Adipose	mRNA stability	0	0	1.21
BLA	alternative polyA	0	0	1.11
BLA	alternative TSS	0	0	1.15
BLA	gene expression	0	0	1.22
BLA	isoform ratio	0	0	1.16
BLA	intron excision ratio	0	0	1.18
BLA	mRNA stability	0	0	1.18
Brain	alternative polyA	0	0	1.15
Brain	alternative TSS	0	0	1.18
Brain	gene expression	0	0	1.18
Brain	isoform ratio	0	0	1.23
Brain	intron excision ratio	0	0	1.22
Brain	mRNA stability	1	0	1.18
Eye	alternative polyA	0	0	0.91
Eye	alternative TSS	0	0	1.1
Eye	gene expression	0	0	1.21
Eye	isoform ratio	0	0	1.22
Eye	intron excision ratio	0	0	1.23
Eye	mRNA stability	0	0	1.22
IC	alternative polyA	0	0	1.13
IC	alternative TSS	0	0	1.18
IC	gene expression	0	0	1.23
IC	isoform ratio	0	0	1.2
IC	intron excision ratio	0	0	1.28
IC	mRNA stability	0	0	1.17
IL	alternative polyA	0	0	1.12
IL	alternative TSS	0	0	1.15
IL	gene expression	0	0	1.2
IL	isoform ratio	0	0	1.19
IL	intron excision ratio	0	0	1.21
IL	mRNA stability	0	0	1.19
LHb	alternative polyA	0	0	1.12
LHb	alternative TSS	0	0	1.34
LHb	gene expression	0	0	1.18
LHb	isoform ratio	0	0	1.26
LHb	intron excision ratio	0	0	1.14
LHb	mRNA stability	0	0	1.15
Liver	alternative polyA	0	0	1.23
Liver	alternative TSS	0	0	1.17
Liver	gene expression	0	0	1.2
Liver	isoform ratio	0	0	1.21
Liver	intron excision ratio	0	0	1.21
Liver	mRNA stability	0	0	1.18
NAcc	alternative polyA	1	0	10.46
NAcc	alternative TSS	0	0	1.19
NAcc	gene expression	0	0	1.19
NAcc	isoform ratio	0	0	1.17
NAcc	intron excision ratio	1	0	1.21
NAcc	mRNA stability	0	0	1.19
OFC	alternative polyA	0	0	1.15
OFC	alternative TSS	0	0	1.2
OFC	gene expression	0	0	1.19
OFC	isoform ratio	0	0	1.13
OFC	intron excision ratio	0	0	1.07
OFC	mRNA stability	0	0	1.19
PL	alternative polyA	0	0	1.19
PL	alternative TSS	0	0	1.2
PL	gene expression	1	0	1.19
PL	isoform ratio	0	0	1.21
PL	intron excision ratio	0	0	1.21
PL	mRNA stability	0	0	1.18
pVTA	alternative polyA	0	0	1.19
pVTA	alternative TSS	0	0	1.29
pVTA	gene expression	0	0	1.21
pVTA	isoform ratio	0	0	1.25
pVTA	intron excision ratio	0	0	1.22
pVTA	mRNA stability	0	0	1.18
RMTg	alternative polyA	0	0	1.04
RMTg	alternative TSS	0	0	1.18
RMTg	gene expression	0	0	1.3
RMTg	isoform ratio	0	0	1.21
RMTg	intron excision ratio	0	0	1.24
RMTg	mRNA stability	0	0	1.23