Hub : Genes

Kif16b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA XM_063283799.1 0.02 0.02 3.3e-03 0.02 0.02 0.01 0.02 3.7e-03 2.3e-03 2.7e-02 3.1e-03
2 NAcc alternative polyA XM_063283799.1 0.03 0.02 1.1e-04 0.02 0.03 0.02 0.02 9.8e-04 7.6e-05 3.5e-04 2.4e-04
3 Liver gene expression Kif16b 0.22 0.09 0.0e+00 0.19 0.18 0.18 0.18 1.8e-20 2.1e-19 8.4e-20 8.4e-20
4 IC gene expression Kif16b 0.11 0.08 3.4e-03 0 0.04 0.02 0.02 2.7e-01 1.4e-02 4.1e-02 5.1e-02
5 NAcc gene expression Kif16b 0.07 0.03 4.2e-09 0.03 0.05 0.04 0.04 7.0e-06 7.3e-08 1.3e-06 2.5e-07
6 Liver alternative polyA XM_063283800.1 0.09 0.06 1.6e-09 0.06 0.07 0.07 0.06 2.4e-07 4.5e-08 4.5e-08 4.5e-07
7 Liver isoform ratio XM_039105044.2 0.05 0.04 1.3e-03 0.01 0.01 0.01 0.01 3.2e-02 1.7e-02 5.1e-02 3.6e-02
8 BLA gene expression Kif16b 0.07 0.05 1.8e-03 0.02 0.04 0.03 0.03 2.7e-02 3.9e-03 1.5e-02 1.6e-02
9 PL gene expression Kif16b 0.03 0.02 7.6e-03 0.01 0.01 0.01 0 3.2e-02 8.0e-03 1.7e-02 2.6e-01
10 Liver isoform ratio XM_063283798.1 0.02 0.01 3.7e-03 0.01 0.02 0 0.01 2.2e-02 5.0e-03 1.7e-01 4.6e-02
11 RMTg intron excision ratio chr3_150516570_150516904 0.1 0.07 8.9e-03 0.05 0.06 0.06 0.04 2.3e-02 1.3e-02 9.2e-03 4.0e-02
12 Adipose alternative polyA XM_063283799.1 0.07 0.04 2.4e-06 0.04 0.03 0.03 0.03 5.4e-05 6.5e-04 4.5e-04 4.1e-04
13 Liver mRNA stability Kif16b 0.12 0.06 1.3e-05 0.02 0.03 0.04 0.03 1.1e-03 1.0e-04 3.1e-05 1.0e-04
14 IC isoform ratio XM_063283800.1 0.12 0.1 9.6e-03 -0 0.01 0.01 0.01 5.5e-01 1.0e-01 1.1e-01 1.6e-01
15 Liver intron excision ratio chr3_150675218_150707483 0.04 0.03 2.2e-04 0.02 0.02 0.02 0.02 3.9e-03 1.5e-03 4.7e-03 1.3e-03
16 Brain gene expression Kif16b 0.21 0.11 3.8e-09 0.06 0.1 0.12 0.11 1.1e-06 6.7e-10 1.1e-11 1.8e-10
17 BLA alternative polyA XM_006235113.5 0.05 0.04 6.2e-03 0.02 0.02 0.03 0.02 2.4e-02 2.6e-02 1.6e-02 4.0e-02
18 BLA alternative polyA XM_006235113.5 0.06 0.04 3.0e-03 0.03 0.02 0.03 0.03 6.9e-03 1.8e-02 6.4e-03 1.2e-02
19 LHb mRNA stability Kif16b 0.12 0.08 5.5e-03 0.06 0.1 0.05 0.06 1.7e-02 2.9e-03 2.5e-02 1.9e-02
20 Liver intron excision ratio chr3_150501111_150502367 0.03 0.02 3.9e-03 0.01 0.01 0 0 1.6e-02 1.8e-02 2.9e-01 1.0e-01
21 Liver alternative polyA XM_063283799.1 0.18 0.08 0.0e+00 0.15 0.15 0.16 0.15 7.0e-16 8.4e-17 1.3e-17 3.4e-16
22 Liver intron excision ratio chr3_150489254_150502367 0.03 0.02 3.2e-03 0.01 0.01 0 0 1.3e-02 1.1e-02 2.6e-01 7.2e-02
23 Adipose gene expression Kif16b 0.78 0.06 0.0e+00 0.58 0.6 0.6 0.59 8.8e-79 2.6e-82 9.2e-83 2.3e-80
24 Adipose mRNA stability Kif16b 0.5 0.12 0.0e+00 0.28 0.29 0.27 0.28 8.8e-32 2.2e-32 5.0e-30 1.0e-31

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.61.23.30.40.4-0.60.10.30.60.7-0.80.7-0.9-1.0-1.10.2-1.0-1.3-1.21.41.41.41.70.21.61.8-1.8
Area under the delay curve0.20.31.9-0.7-0.70.2-0.2-1.00.10.4-0.3-1.10.0-0.11.4-0.70.10.4-0.00.20.1-0.3-0.2-0.0-0.7-0.50.7
BMI with tail9.834.254.37.16.96.77.46.5-7.1-7.06.95.87.06.9-5.25.26.25.7-5.2-5.3-5.3-5.5-3.6-4.4-3.8-3.62.0
BMI without tail4.825.838.55.55.36.26.04.9-6.1-5.96.04.26.26.1-3.54.05.65.6-3.6-5.3-5.3-5.3-4.4-3.6-4.2-4.02.8
Body weight11.751.092.19.59.69.08.79.5-8.2-8.88.59.08.07.6-8.07.46.86.2-6.4-5.4-5.3-5.4-2.4-5.0-2.7-2.60.6
Weight adjusted by age0.20.42.30.60.80.7-0.01.1-0.3-1.00.91.00.40.2-0.71.50.50.20.4-0.8-0.7-0.3-0.50.70.10.0-0.1
Bone surface0.10.32.30.60.50.30.80.1-0.40.2-0.20.30.1-0.0-0.8-0.1-0.3-0.2-1.50.10.10.30.4-0.80.30.5-0.7
Bone volume0.30.51.70.60.50.10.50.30.10.5-0.50.6-0.4-0.4-1.0-0.4-0.6-0.6-1.30.80.80.81.1-0.00.91.0-1.2
Breakpoint value in progressive ratio session0.30.52.00.1-0.10.30.6-0.5-0.9-0.10.2-0.50.60.5-0.21.4-0.10.4-0.6-0.9-1.0-0.6-1.3-1.1-0.9-0.50.5
Number of licking bursts0.20.51.30.30.5-0.2-0.20.70.5-0.0-0.10.9-0.4-0.4-0.80.6-0.3-0.8-0.40.91.00.81.20.31.11.1-1.1
Context. condit. distance diff. score0.30.30.9-0.8-0.7-0.7-0.9-0.50.70.4-0.4-0.6-0.5-0.40.8-0.6-0.2-0.31.00.40.40.20.30.80.1-0.10.2
Locomotion velocity, session 11.71.94.7-2.0-2.1-1.2-1.4-2.11.41.7-1.6-2.2-1.3-1.22.1-1.8-0.8-0.61.00.80.70.6-0.21.6-0.2-0.40.6
Locomotion distance, session 14.25.49.5-3.0-3.0-3.1-2.8-2.92.72.8-2.8-2.7-2.7-2.72.4-2.2-2.2-2.31.51.91.91.91.01.81.11.1-0.5
Locomotion velocity, session 22.12.55.1-2.2-2.2-1.7-1.8-2.31.72.0-1.9-2.2-1.7-1.61.9-2.0-1.4-1.21.21.01.01.10.11.20.40.30.1
Locomotion distance, session 24.96.914.9-3.6-3.7-2.8-3.0-3.92.93.4-3.2-3.7-2.8-2.63.2-3.5-2.4-1.82.21.81.71.70.51.80.50.40.3
Locomotion velocity, session 33.23.67.5-2.4-2.2-2.3-2.6-1.72.71.9-2.0-1.7-2.3-2.02.0-2.1-1.2-1.62.11.81.91.60.92.21.20.7-0.3
Locomotion distance, session 31.11.22.4-1.4-1.3-1.4-1.4-1.01.51.1-1.2-1.0-1.3-1.11.1-1.3-0.7-0.91.21.11.10.90.51.30.70.5-0.2
Stereotopy head waving bouts, day 30.50.62.40.90.90.40.50.7-0.20.0-0.11.0-0.1-0.3-1.50.5-0.7-0.5-1.10.60.60.70.9-0.71.01.2-1.3
Stereotopy head waving duration, day 30.10.10.60.50.50.50.50.3-0.4-0.00.10.40.20.1-0.80.2-0.30.1-0.6-0.0-0.00.10.1-0.60.20.3-0.4
Locomotion velocity, session 71.82.03.9-1.5-1.3-1.2-2.0-1.01.91.5-1.5-0.8-1.8-1.40.8-1.6-1.3-1.11.81.71.71.51.31.51.30.8-0.5
Locomotion distance, session 71.21.53.8-1.3-1.1-0.8-1.5-0.81.71.2-1.1-0.7-1.4-1.00.9-2.0-0.6-0.51.81.51.61.01.21.90.80.2-0.0
Stereotopy head waving bouts, day 70.50.61.00.90.90.90.71.0-0.8-1.01.00.90.90.9-0.60.60.90.8-0.3-0.9-0.9-0.7-0.8-0.2-0.5-0.60.4
Stereotopy head waving duration, day 70.10.10.30.40.40.10.40.4-0.2-0.10.10.40.10.1-0.40.40.1-0.1-0.5-0.0-0.00.10.0-0.40.20.2-0.4
Locomotion velocity, session 81.31.63.8-1.8-1.9-1.5-1.5-1.91.21.5-1.4-1.9-1.2-1.11.7-1.4-1.1-0.81.20.70.60.6-0.10.9-0.0-0.00.4
Locomotion distance, session 84.26.111.9-3.4-3.4-2.9-3.2-3.13.02.7-2.6-3.1-2.6-2.23.2-3.2-1.7-1.62.91.71.71.50.62.60.60.10.5
Degree of sensitization distance0.10.11.00.40.51.00.30.4-0.3-0.20.30.50.30.4-0.5-0.20.10.70.00.10.1-0.10.40.4-0.0-0.30.2
Degree of sensitization stereotypy0.80.81.90.40.50.70.50.6-0.8-1.11.10.31.01.10.10.71.21.00.4-1.4-1.3-1.1-1.40.3-1.0-1.21.0
Conditioned locomotion0.91.13.40.80.90.90.30.80.30.4-0.41.3-0.5-0.6-1.6-0.5-0.8-0.3-0.81.61.61.21.8-0.11.51.2-1.5
Cocaine response after cond. corrected1.31.93.8-1.5-1.4-1.3-1.6-1.21.81.7-1.6-1.0-1.7-1.40.8-1.9-1.4-1.21.31.61.61.41.30.91.10.7-0.5
Cocaine response after cond. not corrected2.03.05.1-1.3-1.3-1.6-1.7-1.22.12.1-2.0-0.7-2.1-1.90.3-2.2-2.0-1.81.12.32.22.12.00.41.91.5-1.4
Cocaine response before conditioning0.40.51.50.40.4-0.10.20.30.20.5-0.50.5-0.4-0.5-0.9-0.5-0.8-0.7-0.70.80.80.90.8-1.01.01.1-1.2
Saline control response0.10.10.60.30.20.70.5-0.2-0.50.4-0.1-0.00.20.3-0.4-0.8-0.50.4-0.40.20.20.00.3-0.2-0.1-0.30.1
Bone: connectivity density1.11.84.8-0.1-0.2-1.3-0.3-0.40.91.3-1.40.1-1.3-1.6-0.70.2-1.6-1.9-1.21.61.61.81.7-0.11.82.2-2.1
Bone: cortical apparent density0.10.10.3-0.1-0.0-0.6-0.50.30.5-0.0-0.10.3-0.4-0.4-0.10.1-0.0-0.50.40.30.30.40.3-0.00.50.5-0.4
Bone: cortical area0.91.45.41.71.80.70.92.1-0.2-1.00.82.30.30.2-2.00.50.5-0.3-1.30.70.80.51.4-0.71.21.0-1.4
Bone: cortical porosity0.70.82.31.41.40.71.21.2-0.7-0.70.61.30.60.2-1.50.90.3-0.1-1.40.00.00.10.4-0.70.50.8-1.0
Bone: cortical porosity0.91.02.61.61.61.01.31.5-0.9-1.00.91.60.80.6-1.50.90.70.3-1.4-0.2-0.2-0.20.2-0.70.30.4-0.7
Bone: cortical thickness1.72.89.12.02.30.40.82.60.1-1.00.63.0-0.0-0.4-2.70.90.3-1.1-1.81.31.41.12.2-1.02.22.1-2.5
Bone: cortical thickness1.11.34.00.30.5-0.8-0.61.01.1-0.1-0.41.2-0.9-1.4-1.00.6-0.4-1.7-0.51.11.21.41.50.82.02.0-2.0
Bone: cortical tissue density0.10.10.4-0.2-0.1-0.6-0.60.20.5-0.0-0.10.1-0.4-0.40.10.1-0.1-0.50.50.20.30.30.20.10.40.4-0.3
Condit. Reinf. active minus inactive responses0.40.41.80.80.90.60.40.9-0.3-0.30.31.10.1-0.0-1.30.2-0.4-0.1-0.30.20.20.40.5-0.90.70.8-0.9
Condit. Reinf. active-inactive response ratio0.20.21.10.70.80.60.30.8-0.3-0.30.30.90.10.0-1.1-0.0-0.20.00.00.10.10.20.5-0.70.50.5-0.6
Condit. Reinf. active responses0.10.10.30.10.30.3-0.20.3-0.2-0.30.20.40.1-0.1-0.40.3-0.3-0.00.5-0.2-0.20.0-0.2-0.50.20.3-0.2
Condit. Reinf. inactive responses0.30.41.3-0.6-0.60.0-0.4-0.6-0.2-0.10.2-0.80.20.20.90.10.10.50.9-0.7-0.7-0.6-1.10.3-0.8-0.81.0
Incentive salience index mean0.10.10.40.00.1-0.1-0.30.10.00.1-0.10.2-0.2-0.4-0.40.2-0.6-0.40.20.20.20.40.3-0.60.50.7-0.5
Condit. Reinf. lever presses0.20.30.9-0.5-0.5-0.4-0.3-0.5-0.3-0.30.3-0.70.30.20.90.60.20.20.6-0.8-0.8-0.7-1.0-0.3-0.8-0.60.8
Condit. Reinf. active minus inactive responses0.30.53.20.60.51.80.90.1-0.80.00.30.20.60.9-0.5-1.40.11.40.2-0.3-0.3-0.4-0.2-0.0-0.6-0.90.6
Condit. Reinf. active-inactive response ratio0.30.52.00.40.31.40.8-0.0-0.7-0.20.4-0.10.70.9-0.0-1.10.51.3-0.1-0.6-0.6-0.7-0.50.2-0.9-1.20.9
Condit. Reinf. active responses0.50.82.80.50.41.70.70.2-1.0-0.40.70.10.91.2-0.1-0.80.51.70.6-0.9-0.9-0.9-0.80.0-1.0-1.21.1
Condit. Reinf. inactive responses0.20.30.90.60.60.50.40.6-0.8-0.70.70.50.60.7-0.50.90.30.50.3-0.8-0.8-0.5-0.6-0.4-0.3-0.10.1
Condit. Reinf. lever presses1.82.66.10.60.32.01.7-0.3-2.0-0.81.2-0.61.92.00.4-0.41.22.4-0.5-2.0-2.1-2.1-1.9-0.2-2.5-2.32.1
Condit. Reinf. lever reinforcers received0.70.93.20.40.31.80.9-0.2-1.2-0.20.6-0.21.01.3-0.0-1.00.41.80.4-1.0-1.0-1.1-0.9-0.1-1.3-1.41.2
Conditioned reinforcement - actives0.62.45.5-1.5-1.9-2.3-0.6-2.31.32.3-2.3-2.1-1.6-1.41.5-1.3-1.6-1.6-0.41.61.61.31.20.40.50.8-0.6
Conditioned reinforcement - inactives0.51.32.8-0.8-1.0-1.5-0.7-1.01.01.3-1.4-0.8-1.2-1.20.4-0.9-1.4-1.5-0.21.31.41.31.70.11.01.2-1.0
Conditioned locomotion2.13.26.0-2.0-2.2-2.1-1.6-2.41.82.4-2.4-2.2-2.0-2.01.7-2.2-2.0-1.70.91.61.61.61.10.10.91.1-0.6
Patch foraging indifference point 0 sec0.10.30.8-0.7-0.7-0.9-0.9-0.70.50.6-0.6-0.6-0.7-0.50.2-0.3-0.9-0.70.60.20.30.50.40.20.40.4-0.2
Patch foraging indifference point AUC0.61.43.8-1.8-1.6-1.2-2.0-1.41.51.2-1.2-1.4-1.4-1.61.3-0.6-1.2-1.11.50.70.70.90.30.70.60.7-0.1
Delay disc. indifference point, 0s delay0.40.41.20.30.11.00.8-0.2-0.9-0.30.5-0.30.80.70.5-0.50.60.9-0.7-0.5-0.6-0.9-0.2-0.4-1.1-0.80.8
Delay disc. indifference point, 16s delay0.50.71.4-1.0-1.0-0.7-0.9-1.20.81.1-1.1-1.1-0.9-1.11.0-1.0-1.0-0.70.40.90.90.70.2-0.30.40.6-0.3
Delay disc. indifference point, 2s delay1.01.23.40.30.11.21.2-0.4-1.3-0.50.7-0.71.31.20.70.11.21.6-0.5-1.1-1.1-1.5-1.0-0.2-1.8-1.51.6
Delay disc. indifference point, 24s delay0.61.02.4-1.1-1.0-1.2-1.2-0.61.50.9-1.0-0.6-1.2-1.21.3-1.6-0.2-0.90.61.41.40.90.80.20.70.4-0.3
Delay disc. indifference point, 4s delay0.70.81.80.30.41.00.30.6-0.6-1.11.10.20.91.00.40.21.31.30.8-0.9-0.9-1.1-1.20.5-1.0-1.21.1
Delay disc. indifference point, 8s delay0.30.63.6-1.0-1.1-0.2-0.5-1.20.60.7-0.6-1.3-0.4-0.31.9-1.10.10.30.10.50.5-0.10.10.4-0.5-0.40.7
Indifference point function ln k0.20.51.81.11.00.41.21.0-0.6-0.60.51.00.60.7-0.91.00.60.3-1.30.00.0-0.20.30.10.10.1-0.4
Indifference point function log k0.20.51.81.11.00.41.21.0-0.6-0.60.51.00.60.7-0.91.00.60.3-1.30.00.0-0.20.30.10.10.1-0.4
Patch foraging total patch changes 0 sec0.20.71.5-1.2-1.2-1.2-1.2-1.10.80.9-0.9-1.1-0.9-0.70.7-0.5-1.1-0.81.00.30.30.60.30.60.30.4-0.0
Patch foraging total patch changes 12 sec0.10.10.4-0.3-0.20.3-0.3-0.2-0.2-0.20.3-0.30.20.20.30.10.10.40.6-0.5-0.5-0.4-0.30.1-0.5-0.50.6
Patch foraging total patch changes 18 sec0.92.16.2-2.1-2.0-1.5-2.2-2.01.41.5-1.4-2.0-1.4-1.21.7-1.6-1.5-0.92.50.40.40.7-0.10.90.1-0.10.5
Patch foraging total patch changes 24 sec0.20.82.6-1.3-1.3-0.7-1.2-1.40.60.9-0.8-1.4-0.7-0.71.1-1.0-0.9-0.41.60.20.10.2-0.50.3-0.2-0.20.6
Patch foraging total patch changes 6 sec0.20.41.6-0.9-0.8-0.9-1.2-0.60.50.4-0.4-0.6-0.6-0.40.3-0.3-0.8-0.61.3-0.1-0.10.30.10.40.20.30.1
Patch foraging time to switch 0 sec0.62.34.82.22.21.82.12.0-1.9-1.71.82.01.71.7-1.90.81.31.2-1.4-1.1-1.1-1.1-0.6-1.1-0.6-0.50.0
Patch foraging water rate 0 sec0.72.76.9-2.6-2.5-1.8-2.5-2.21.91.6-1.6-2.4-1.6-1.62.5-1.1-1.0-1.02.00.80.80.70.11.20.1-0.00.7
Patch foraging water rate 12 sec0.72.95.8-2.3-2.2-2.1-2.4-1.72.41.7-1.8-1.7-2.0-1.72.1-2.0-1.0-1.31.91.51.51.30.70.80.80.6-0.1
Patch foraging water rate 18 sec2.45.311.0-2.6-2.4-3.0-3.2-1.73.32.2-2.4-1.5-2.9-2.51.9-1.8-1.7-2.32.32.72.72.31.91.92.01.5-0.9
Patch foraging water rate 24 sec2.23.28.5-2.4-2.1-1.9-2.9-1.32.91.4-1.5-1.3-2.2-1.82.1-1.6-0.7-1.22.61.51.61.40.72.51.10.40.1
Patch foraging water rate 6 sec1.62.44.4-1.2-1.0-1.6-2.0-0.52.11.3-1.5-0.2-2.0-1.90.5-1.0-1.5-1.71.42.02.11.91.80.52.01.7-1.4
Seeking ratio, delayed vs. immediate footshock0.20.31.40.80.70.60.90.6-0.5-0.40.40.70.50.6-0.7-0.90.40.3-1.2-0.0-0.1-0.20.2-0.4-0.0-0.3-0.2
Distance traveled before self-admin0.92.05.60.20.11.20.7-0.1-1.5-1.11.2-0.51.51.50.50.71.11.80.3-2.1-2.2-1.9-2.4-0.0-2.1-1.91.9
Distance traveled after self-admin0.20.31.0-0.8-0.7-0.5-1.0-0.50.70.4-0.4-0.5-0.6-0.70.6-0.5-0.4-0.40.90.50.50.3-0.0-0.10.20.20.1
Extensor digitorum longus weight0.31.12.21.00.91.51.20.9-1.2-1.31.20.71.31.2-0.40.81.31.2-1.0-0.9-1.0-1.2-0.7-0.3-1.0-0.90.7
Bone: elastic displacement0.20.20.70.70.70.60.60.7-0.4-0.50.50.70.40.1-0.70.60.40.1-0.8-0.2-0.2-0.20.1-0.30.10.2-0.3
Bone: elastic work2.33.05.52.32.31.92.22.2-2.0-2.12.02.02.01.6-1.91.61.81.2-2.3-1.3-1.3-1.4-0.6-1.3-0.7-0.50.1
Bone: endosteal estimation1.22.95.91.51.32.42.20.8-2.2-1.41.60.62.12.3-0.70.41.62.4-1.4-1.7-1.8-2.0-1.6-1.0-2.0-2.11.5
Bone: endosteal perimeter0.20.51.70.30.11.00.8-0.2-0.8-0.00.3-0.30.71.00.0-0.90.41.2-0.3-0.4-0.4-0.8-0.5-0.1-1.0-1.31.0
Epididymis fat weight5.930.053.37.37.37.06.96.9-6.4-6.56.46.66.25.9-6.05.45.24.9-5.3-4.2-4.1-4.3-1.7-4.1-2.4-2.20.7
Delta time in closed arm before/after self-admin0.30.31.0-0.5-0.4-0.7-0.7-0.30.40.4-0.4-0.3-0.5-0.50.1-0.6-0.8-0.70.6-0.1-0.10.5-0.2-1.00.50.5-0.5
Delta time in open arm before/after self-admin1.21.43.61.71.81.71.21.9-1.1-1.51.41.91.11.1-1.61.51.00.7-0.9-0.5-0.5-0.60.3-0.10.00.0-0.2
Diff in mean of infusions in LGA sessions0.51.03.3-0.1-0.20.70.4-0.5-0.9-0.40.6-0.70.90.90.6-0.10.61.00.5-1.6-1.6-1.2-1.8-1.4-1.5-1.31.3
Delay discount exponential model param0.20.32.00.80.80.00.41.0-0.3-0.50.41.00.20.3-1.40.7-0.1-0.3-0.2-0.4-0.30.20.1-0.20.50.3-0.6
Extinction: sum of active levers before priming0.20.31.2-0.6-0.7-0.3-0.3-0.8-0.10.3-0.2-0.90.0-0.10.5-0.2-0.30.10.5-0.7-0.7-0.3-1.1-0.8-0.6-0.60.5
Active lever presses in extinction session 60.70.73.71.31.10.81.60.6-1.1-0.40.40.70.80.8-1.31.20.30.3-1.9-0.1-0.1-0.30.2-0.4-0.20.2-0.4
Bone: final force0.61.04.21.41.61.30.82.0-0.4-1.31.22.00.70.7-1.50.21.20.5-0.60.00.1-0.20.50.20.5-0.0-0.4
Bone: final moment0.61.04.21.41.61.10.72.0-0.3-1.21.12.00.60.5-1.60.21.00.2-0.70.20.2-0.00.70.00.60.2-0.6
Food consumed during 24 hour testing period0.61.33.21.31.40.10.81.40.0-0.20.11.7-0.1-0.2-1.70.7-0.1-0.8-1.71.21.30.91.8-0.21.41.4-1.7
Glucose1.52.34.61.81.82.11.81.7-1.9-1.81.81.61.81.9-1.41.61.41.5-1.4-1.3-1.2-1.4-0.6-0.7-1.0-1.00.6
Heart weight1.21.94.01.91.81.82.01.5-1.7-1.31.51.51.61.7-1.40.51.31.4-1.4-0.8-0.8-1.1-0.6-1.8-0.8-0.90.4
Delay discount hyperbolic model param0.10.21.20.40.4-0.30.00.60.1-0.10.00.7-0.2-0.1-1.10.3-0.4-0.50.0-0.1-0.00.40.2-0.00.70.5-0.7
Intermittent access intake day 1-15 change0.10.72.70.0-0.4-0.11.2-1.1-1.00.3-0.1-1.10.70.60.5-0.20.20.7-1.7-0.6-0.7-0.8-0.7-1.6-1.4-0.90.8
Intermittent access intake escalation0.10.73.4-0.1-0.5-0.21.1-1.2-0.80.5-0.2-1.20.60.50.7-0.50.20.7-1.8-0.4-0.5-0.8-0.4-1.4-1.4-1.00.9
Intermittent access intake escalation 20.71.14.50.60.20.41.7-0.5-1.4-0.20.5-0.61.21.20.20.40.81.1-2.1-1.0-1.1-1.3-0.7-1.0-1.7-1.21.1
Intermitt. access day 1 inactive lever presses0.11.04.11.00.70.31.40.3-1.6-0.70.70.31.10.9-1.00.7-0.00.1-1.3-1.5-1.5-0.7-0.9-2.0-0.7-0.3-0.1
Intermitt. access day 15 inactive lever presses0.21.06.21.31.1-0.41.50.8-0.9-0.30.11.00.40.5-1.70.2-0.3-0.7-1.7-0.1-0.00.30.9-2.50.50.7-1.3
Intermitt. access escalation Index0.20.61.41.11.11.00.91.0-0.7-0.60.61.10.60.5-1.20.80.30.3-1.1-0.1-0.1-0.10.2-1.00.20.3-0.5
Intermittent access day 1 total infusions0.10.31.00.70.70.10.60.80.1-0.30.20.90.10.2-0.4-0.10.70.0-0.40.80.90.21.0-0.60.40.2-0.4
Intermittent access day 15 total infusions0.20.43.40.70.5-0.01.20.2-0.40.1-0.00.30.30.4-0.3-0.00.60.2-1.80.70.7-0.11.0-1.3-0.1-0.0-0.2
Intermittent access terminal intake (last 3 days)0.30.63.91.10.90.21.40.6-0.7-0.30.30.70.60.6-0.60.80.60.3-2.00.30.3-0.20.9-1.1-0.10.1-0.3
Intermittent access total infusions0.50.52.61.00.90.01.10.7-0.3-0.20.10.90.20.2-0.80.40.3-0.2-1.60.80.80.21.4-1.00.40.5-0.7
Intermittent access day 1 locomotion0.20.41.7-0.4-0.5-0.50.1-0.60.70.7-0.7-0.5-0.4-0.30.8-1.30.3-0.0-0.11.11.10.30.8-0.10.0-0.20.2
Intermittent access day 15 total locomotion0.31.34.20.1-0.1-0.90.2-0.50.41.2-1.2-0.1-0.8-1.0-0.5-0.7-1.3-1.3-1.51.61.71.32.0-1.41.11.5-1.5
Intermittent access total locomotion0.91.12.4-1.0-1.1-1.4-0.6-1.21.21.4-1.4-1.0-1.1-1.01.0-1.6-0.7-0.9-0.01.41.40.91.30.10.50.5-0.4
Intermittent access standard deviation0.10.41.9-0.6-0.9-0.70.0-1.40.01.1-0.9-1.3-0.4-0.50.6-0.5-0.9-0.4-0.70.30.30.20.3-0.4-0.30.20.1
Left kidney weight0.75.912.83.63.52.93.53.1-2.9-2.42.43.12.52.4-3.32.61.71.7-3.0-1.4-1.3-1.4-0.2-2.6-0.5-0.3-0.4
Right kidney weight0.42.65.92.42.32.02.31.9-1.9-1.41.52.11.61.4-2.21.60.91.1-2.2-0.8-0.8-0.80.1-2.2-0.2-0.0-0.4
Cocaine induced anxiety0.10.41.2-0.6-0.60.0-0.3-0.60.30.2-0.1-0.80.00.21.1-0.70.70.70.7-0.1-0.1-0.5-0.50.4-0.8-1.01.1
Post-drug Anxiety1.72.04.80.91.11.60.81.4-1.0-1.81.81.01.51.7-0.11.12.21.90.7-1.5-1.5-1.6-1.30.8-1.3-1.71.5
Baseline Anxiety2.03.36.72.12.32.41.42.5-2.0-2.62.52.32.01.8-1.72.61.51.5-0.0-2.0-1.9-1.5-1.10.0-0.7-0.70.4
Tail length0.31.95.71.92.12.21.12.3-1.0-1.61.52.41.00.7-2.12.00.70.7-0.9-0.4-0.3-0.30.4-0.30.50.6-0.7
Length with tail2.29.823.04.64.74.43.64.7-3.2-3.73.54.83.02.6-4.43.72.22.1-3.1-1.6-1.5-1.40.2-2.00.10.2-1.0
Length without tail1.78.823.04.64.63.43.84.6-2.9-3.12.84.82.62.3-4.73.11.81.3-3.8-0.7-0.6-0.81.4-2.00.70.7-1.7
Times rat made contact with spout0.80.92.00.70.61.11.20.2-1.4-0.80.90.01.21.0-0.20.90.71.0-1.0-1.2-1.2-1.2-1.0-0.4-1.2-1.00.8
Lifetime Intake0.30.41.60.50.4-0.40.60.10.00.3-0.40.3-0.2-0.2-0.50.1-0.2-0.5-1.30.80.90.51.2-1.10.50.7-0.8
Liver weight, left1.93.45.91.81.92.11.82.0-2.0-2.42.41.72.22.4-1.11.42.32.1-0.6-2.0-1.9-2.0-1.0-0.7-1.5-1.81.4
Liver weight, right1.93.36.92.62.62.62.32.4-2.2-2.02.02.41.91.8-2.42.41.11.5-1.9-1.2-1.2-1.10.0-0.6-0.3-0.3-0.2
Locomotor activity1.01.64.1-0.0-0.30.80.8-0.5-1.1-0.70.9-0.81.21.21.1-0.21.31.6-0.3-1.6-1.6-1.7-1.7-1.4-2.0-2.01.9
Locomotor testing distance0.30.72.4-0.9-1.1-0.5-0.1-1.40.10.5-0.4-1.50.0-0.11.5-1.30.20.2-0.1-0.5-0.5-0.6-1.1-0.7-1.1-1.11.1
Locomotor testing rearing0.10.41.6-0.6-0.9-0.60.1-1.2-0.20.6-0.5-1.3-0.0-0.20.9-0.6-0.3-0.2-0.6-0.3-0.3-0.3-0.3-1.0-0.7-0.50.5
Locomotion in novel chamber0.91.22.7-0.6-0.5-1.4-1.2-0.11.40.8-1.00.2-1.4-1.2-0.3-0.4-1.1-1.60.41.31.31.51.60.31.61.3-1.3
Locomotion in novel chamber post-restriction1.23.69.3-1.1-1.1-1.9-1.4-1.21.52.0-2.2-0.7-2.1-2.6-0.30.4-3.0-2.6-0.31.91.92.52.0-0.52.32.9-2.5
Fecal boli incidents, locomotor time 10.30.92.9-1.2-1.2-0.7-1.0-0.91.10.6-0.5-1.1-0.6-0.41.7-1.30.30.11.40.10.10.0-1.11.5-0.3-1.01.0
Change in fecal boli incidents, locomotor task1.31.44.00.80.9-0.40.10.8-0.00.1-0.31.2-0.5-0.6-1.81.7-1.3-1.3-0.61.01.11.21.5-1.51.62.0-2.0
Time >=10cm from walls, locomotor time 10.10.10.40.20.2-0.10.00.20.10.2-0.20.3-0.2-0.3-0.30.1-0.4-0.4-0.20.10.20.50.3-0.60.60.6-0.7
Bouts of movement, locomotor time 10.60.72.6-1.0-1.0-0.6-0.7-1.11.01.1-1.1-1.0-0.9-0.81.2-1.6-0.6-0.40.50.60.50.6-0.31.20.30.0-0.1
Total resting periods, locomotor time 10.91.02.9-1.2-1.3-0.8-1.0-1.31.21.3-1.3-1.2-1.1-1.01.2-1.7-0.9-0.60.80.60.60.8-0.31.10.40.1-0.2
Rest time, locomotor task time 10.10.10.3-0.4-0.5-0.2-0.3-0.50.30.6-0.5-0.5-0.4-0.40.4-0.1-0.5-0.2-0.10.40.40.3-0.00.50.10.0-0.1
Distance moved, locomotor task time 10.10.41.2-0.3-0.2-0.8-0.6-0.00.70.3-0.40.0-0.6-0.60.0-1.1-0.3-0.80.60.70.70.61.00.00.70.9-0.6
Vertical activity count, locomotor time 10.10.41.11.01.00.20.80.9-0.6-0.50.40.90.40.4-1.10.10.2-0.2-1.0-0.1-0.1-0.00.6-0.80.30.7-0.7
Time >=10cm from walls, locomotor time 20.82.46.72.22.01.42.11.7-1.9-1.31.21.81.41.1-2.12.40.40.5-2.6-1.0-1.0-0.6-0.5-2.3-0.10.4-0.8
Bouts of movement, locomotor time 20.41.44.4-0.6-0.70.80.1-0.8-0.6-0.30.5-1.20.81.01.50.30.91.71.0-1.4-1.4-1.4-2.10.4-1.8-2.02.0
Total resting periods, locomotor time 20.41.75.4-0.5-0.60.80.2-0.6-0.7-0.50.7-1.11.01.21.50.41.11.81.0-1.6-1.7-1.6-2.30.4-2.0-2.12.2
Rest time, locomotor task time 20.71.24.8-0.6-0.50.3-0.4-0.10.1-0.60.6-0.60.50.81.40.21.31.31.2-0.9-0.9-1.1-1.52.2-1.3-1.91.8
Distance moved, locomotor task time 21.21.64.1-0.2-0.3-0.9-0.3-0.70.71.4-1.4-0.2-1.1-1.5-0.7-1.2-1.8-1.7-0.71.51.51.61.8-1.11.52.0-1.8
Vertical activity count, locomotor time 20.30.82.30.30.10.10.4-0.4-0.00.8-0.80.0-0.4-0.8-0.7-1.1-1.1-0.8-1.51.00.90.91.5-1.40.81.3-1.2
Light reinforcement 10.20.82.0-0.9-1.0-1.2-0.5-1.40.51.3-1.3-1.2-0.9-1.20.70.2-1.3-1.1-0.30.70.60.80.60.20.40.7-0.5
Light reinforcement 20.20.52.3-0.7-0.9-1.5-0.2-1.00.50.9-1.0-1.0-0.7-0.70.60.7-0.8-1.0-0.50.30.30.60.20.30.30.7-0.4
Bone: marrow area1.12.75.71.41.22.42.10.7-2.1-1.31.50.52.02.2-0.60.31.52.3-1.3-1.7-1.7-1.9-1.5-1.0-1.9-2.11.5
Bone: maximum diameter0.20.41.20.91.00.90.71.0-0.5-0.70.71.10.50.6-0.90.30.50.4-0.70.00.0-0.20.40.40.1-0.1-0.2
Bone: maximum force0.51.14.01.51.71.40.92.0-0.5-1.31.22.00.80.8-1.5-0.01.20.6-0.9-0.00.1-0.30.5-0.10.4-0.0-0.3
Bone: maximum moment0.61.14.21.61.71.21.02.0-0.5-1.21.12.10.70.6-1.70.21.00.4-1.10.10.1-0.10.6-0.40.50.2-0.6
Mean time between licks in bursts0.63.410.81.01.3-0.8-0.51.61.00.3-0.62.2-1.3-1.4-2.51.0-1.6-2.1-0.31.92.12.32.8-0.33.13.3-3.2
Mean num. licks in bursts0.30.71.70.30.10.90.9-0.3-1.1-0.30.5-0.51.00.80.3-0.00.51.0-0.4-1.3-1.3-1.1-1.3-0.4-1.3-1.21.0
Cd content in liver0.30.31.20.70.80.80.21.00.0-0.40.31.1-0.0-0.2-0.90.5-0.00.1-0.20.40.40.40.70.20.80.6-0.8
Co content in liver1.82.15.50.10.3-0.7-0.80.61.20.8-1.01.0-1.4-1.5-1.3-0.0-1.5-1.7-0.12.12.12.02.10.32.42.3-2.3
Cu content in liver0.20.20.8-0.00.0-0.2-0.30.10.30.2-0.30.2-0.4-0.5-0.50.8-0.6-0.50.30.40.40.60.30.70.70.9-0.7
Fe content in liver2.32.811.52.42.11.82.71.5-2.2-1.11.31.71.71.5-2.11.00.71.0-2.9-0.5-0.5-0.90.4-3.4-0.5-0.1-0.4
K content in liver0.90.82.6-1.3-1.2-1.3-1.1-1.00.50.1-0.2-1.3-0.2-0.21.60.40.2-0.41.5-0.8-0.8-0.4-1.40.6-0.7-0.50.9
Mg content in liver0.20.21.10.30.4-0.10.00.6-0.3-0.70.60.50.40.6-0.31.00.50.10.6-0.6-0.6-0.4-0.40.6-0.2-0.10.2
Mn content in liver1.31.43.9-1.6-1.5-1.2-1.7-1.31.41.3-1.2-1.2-1.3-0.91.2-2.0-1.1-0.71.90.60.60.80.31.50.4-0.10.2
Na content in liver0.30.31.4-0.1-0.3-0.20.5-0.9-0.70.4-0.4-0.90.2-0.40.00.6-0.7-0.5-1.1-0.3-0.4-0.1-0.3-1.2-0.40.3-0.2
Rb content in liver1.01.23.71.21.31.10.81.6-1.0-1.61.41.41.11.0-1.01.91.20.6-0.6-1.0-1.0-0.9-0.70.8-0.4-0.30.1
Se content in liver1.72.06.92.02.11.31.32.3-1.3-1.81.52.31.20.8-2.12.60.80.2-1.4-0.9-0.8-0.4-0.1-0.60.40.7-0.9
Sr content in liver1.31.11.8-1.3-1.2-0.9-1.4-1.21.31.3-1.3-1.0-1.3-1.30.9-1.3-1.2-0.91.00.90.91.00.50.90.70.7-0.4
Zn content in liver0.91.03.00.90.9-0.30.60.8-0.10.2-0.31.1-0.3-0.4-1.60.1-0.8-1.1-1.31.01.01.01.3-1.31.31.6-1.7
Bone: minimum diameter0.40.82.41.31.41.31.01.5-0.7-1.01.01.50.81.0-1.3-0.11.00.8-0.8-0.1-0.1-0.40.3-0.60.0-0.4-0.0
Time in familiar zone, hab. session 10.30.31.40.60.6-0.10.50.4-0.3-0.10.00.60.1-0.2-0.90.8-0.3-0.6-1.20.40.40.30.4-0.40.50.7-0.9
Time in novel zone, hab. session 10.60.71.8-0.1-0.10.90.1-0.1-0.6-0.50.7-0.40.70.90.5-0.40.71.31.0-1.2-1.2-1.0-1.1-0.2-1.2-1.31.3
Total zone transitions, hab. session 11.21.73.4-1.1-1.1-1.5-1.3-1.11.31.5-1.6-0.8-1.6-1.80.3-0.4-1.8-1.8-0.11.31.31.61.20.91.41.6-1.2
Total locomotion distance, hab. session 11.21.73.4-1.5-1.6-1.5-1.5-1.71.31.7-1.7-1.5-1.5-1.50.9-0.9-1.8-1.40.80.90.81.20.60.80.81.1-0.6
Locomotion velocity, hab. session 11.82.64.6-1.7-1.7-2.0-1.9-1.71.82.0-2.0-1.5-2.0-2.00.9-1.1-2.1-2.01.01.41.31.71.10.91.31.5-1.1
Time in familiar zone, hab. session 20.50.52.2-0.7-1.0-0.6-0.0-1.50.21.2-1.1-1.3-0.5-0.70.6-1.0-0.9-0.4-0.70.60.50.40.1-0.3-0.10.1-0.1
Time in novel zone, hab. session 20.91.01.91.01.11.20.81.3-0.9-1.41.41.11.11.2-0.51.01.21.10.2-1.0-1.0-1.0-0.6-0.2-0.6-0.70.6
Total zone transitions, hab. session 20.30.41.4-0.7-0.8-0.7-0.2-1.20.31.1-0.9-1.0-0.5-0.60.5-0.7-0.8-0.4-0.10.40.40.40.00.3-0.0-0.00.0
Total locomotion distance, hab. session 21.41.97.1-1.8-2.1-1.1-1.0-2.70.72.0-1.7-2.5-1.1-1.01.7-1.8-1.7-0.50.80.40.30.5-0.30.7-0.4-0.30.5
Locomotion velocity, hab. session 22.02.77.8-2.2-2.4-1.6-1.5-2.81.32.4-2.2-2.6-1.6-1.51.8-2.0-2.1-1.11.10.90.81.10.10.90.20.20.1
Novel to familiar place preference ratio0.10.10.80.00.20.2-0.20.50.2-0.40.40.40.10.20.0-0.50.60.30.9-0.4-0.3-0.2-0.60.3-0.0-0.50.3
Novelty place preference0.10.10.60.30.40.3-0.10.80.2-0.50.40.70.10.2-0.2-0.30.60.20.6-0.2-0.2-0.1-0.30.10.2-0.20.0
Time in novel zone, NPP test0.20.30.90.50.70.60.30.9-0.2-0.80.70.80.40.5-0.4-0.10.80.50.4-0.6-0.5-0.4-0.6-0.1-0.1-0.50.2
Total zone transitions, NPP test0.91.43.4-1.6-1.7-1.6-1.3-1.91.11.5-1.4-1.8-1.2-1.21.4-1.3-1.2-1.00.80.50.40.70.00.90.10.20.1
Total locomotion distance, NPP test2.63.610.0-2.7-2.9-2.1-2.0-3.21.62.4-2.2-3.1-1.7-1.52.6-2.6-1.8-1.01.80.70.60.8-0.11.2-0.2-0.20.7
Locomotion velocity, NPP test3.04.39.9-2.9-3.0-2.4-2.4-3.12.12.7-2.4-3.0-2.1-1.82.6-2.7-2.0-1.42.11.11.11.20.41.50.20.20.4
Intraocular pressure0.50.71.8-0.30.0-0.6-1.10.61.30.2-0.30.7-1.0-0.6-0.2-0.6-0.2-0.81.21.21.31.01.30.91.30.6-0.7
Delta distance traveled before/after self-admin2.52.75.4-1.2-1.0-1.6-1.9-0.62.21.4-1.6-0.3-2.0-2.10.5-1.2-1.5-1.90.92.32.32.02.2-0.02.01.9-1.5
Delta ambulatory time before/after self-admin1.32.24.8-1.1-0.8-1.4-1.9-0.32.11.1-1.3-0.1-1.8-1.80.5-1.4-1.1-1.71.32.12.21.81.90.31.91.6-1.2
Parametrial fat weight17.440.963.77.77.57.68.07.0-8.0-7.67.66.27.77.1-5.66.86.46.0-5.4-6.1-6.1-6.0-4.5-3.9-4.2-4.02.1
Pavlov. Cond. lever latency0.40.52.11.21.01.11.30.6-0.9-0.10.30.80.60.5-1.4-0.2-0.10.4-1.10.10.0-0.00.2-0.90.10.1-0.4
Pavlov. Cond. magazine entry latency1.11.52.81.11.21.21.11.3-1.3-1.71.61.01.41.3-0.61.61.41.1-0.7-1.4-1.4-1.3-1.2-0.6-0.9-0.90.7
Pavlov. Cond. change in total contacts0.30.32.2-0.4-0.1-0.3-0.90.50.3-0.80.60.30.00.00.50.70.5-0.01.5-0.6-0.6-0.3-0.60.40.0-0.10.3
Pavlov. Cond. index score0.20.21.10.20.3-0.1-0.10.6-0.2-0.90.70.40.40.40.11.00.80.10.2-0.6-0.6-0.5-0.5-0.1-0.3-0.20.3
Pavlov. Cond. latency score0.10.10.5-0.3-0.2-0.7-0.60.20.4-0.40.20.0-0.1-0.20.50.70.3-0.40.5-0.2-0.2-0.1-0.20.30.10.10.0
Pavlov. Cond. lever contacts0.20.20.8-0.5-0.4-0.1-0.5-0.10.1-0.40.3-0.40.10.20.90.60.50.30.6-0.6-0.6-0.5-0.50.4-0.5-0.50.7
Pavlov. Cond. magazine entry number1.41.83.7-1.1-1.3-1.4-1.0-1.51.31.9-1.8-1.2-1.6-1.50.5-1.6-1.8-1.40.21.61.51.51.30.31.11.2-1.0
Pavlov. Cond. intertrial magazine entries1.31.53.7-1.3-1.3-1.0-1.5-1.31.41.7-1.5-1.0-1.5-1.30.7-1.9-1.6-1.01.41.21.21.31.00.31.00.7-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.41.20.20.30.10.10.6-0.5-1.10.90.30.70.60.31.11.00.40.2-1.0-0.9-0.9-0.8-0.1-0.7-0.60.6
Pavlov. Cond. response bias1.01.22.61.01.11.00.81.3-1.1-1.61.51.01.31.2-0.41.51.41.0-0.2-1.3-1.2-1.2-1.0-0.4-0.8-0.80.7
Pavlov. Cond. lever latency1.92.66.1-1.7-1.5-2.5-2.1-1.12.31.5-1.7-0.9-2.0-2.11.1-0.7-1.3-2.11.21.81.81.71.20.91.61.4-1.1
Pavlov. Cond. magazine entry latency0.60.92.40.90.71.51.50.3-1.3-0.60.80.31.11.1-0.40.00.81.3-1.3-0.7-0.7-1.0-0.5-0.2-1.1-1.10.8
Pavlov. Cond. change in total contacts1.53.68.41.91.72.92.60.9-2.8-1.51.80.82.42.4-1.20.71.32.5-1.6-1.9-2.0-2.1-1.4-1.5-2.1-1.81.4
Pavlov. Cond. index score1.62.66.31.81.52.52.31.1-2.3-1.41.60.92.02.0-1.10.71.32.0-1.5-1.5-1.6-1.7-1.0-0.7-1.6-1.51.0
Pavlov. Cond. latency score1.11.84.61.51.32.21.90.9-1.9-1.21.40.81.71.7-1.00.61.11.7-1.3-1.3-1.3-1.4-0.8-0.5-1.3-1.20.8
Pavlov. Cond. lever contacts2.02.96.31.81.52.52.41.0-2.5-1.51.70.82.22.1-1.10.81.32.1-1.5-1.8-1.9-1.8-1.3-1.1-1.7-1.51.1
Pavlov. Cond. magazine entry number1.11.43.8-1.4-1.2-1.9-1.8-0.81.61.0-1.2-0.8-1.5-1.40.8-0.3-1.1-1.51.40.80.91.20.50.51.11.2-0.7
Pavlov. Cond. intertrial magazine entries0.20.41.7-0.9-0.8-1.1-1.0-0.50.80.4-0.4-0.6-0.6-0.30.8-0.6-0.2-0.41.30.20.30.30.00.40.10.10.2
Pavlov. Cond. lever-magazine prob. diff.2.03.26.82.01.82.62.51.3-2.5-1.71.91.12.32.2-1.31.01.52.1-1.8-1.7-1.7-1.9-1.1-0.9-1.7-1.51.0
Pavlov. Cond. response bias2.02.87.31.81.62.72.31.1-2.3-1.51.71.02.12.2-1.10.61.42.2-1.5-1.6-1.6-1.8-1.1-0.7-1.6-1.61.1
Time in closed arm before self-admin0.20.42.70.40.40.10.10.60.2-0.20.10.7-0.0-0.0-0.51.20.2-0.2-0.30.70.70.21.21.70.40.4-0.2
Time in closed arm after self-admin1.21.43.1-0.6-0.4-1.2-1.2-0.21.30.9-1.10.1-1.4-1.4-0.2-0.4-1.3-1.70.51.41.51.51.80.51.71.5-1.4
Time in open arm before self-admin0.30.45.40.0-0.2-0.00.6-0.8-0.60.5-0.4-0.70.1-0.10.1-1.0-0.60.2-0.6-0.3-0.3-0.1-0.7-2.3-0.40.0-0.1
Time in open arm after self-admin0.70.82.11.11.01.31.30.6-1.4-0.70.80.61.10.7-1.10.70.20.7-1.1-0.9-0.9-0.7-0.5-1.4-0.60.0-0.0
Bone: periosteal estimation0.71.73.81.81.72.01.91.5-1.5-1.31.41.51.51.6-1.40.31.31.4-1.6-0.7-0.7-1.0-0.3-1.0-0.7-0.90.3
Bone: periosteal perimeter0.10.21.20.60.50.90.60.2-0.30.20.00.40.20.4-0.7-1.1-0.10.5-0.60.60.60.10.7-0.20.1-0.2-0.1
Bone: post-yield work0.30.52.30.90.80.91.10.4-0.60.10.00.60.30.3-1.1-1.0-0.20.3-1.50.50.50.20.8-1.50.20.2-0.5
Progressive ratio test 1 active lever presses0.00.10.30.2-0.0-0.20.6-0.2-0.40.0-0.0-0.30.30.30.10.40.20.2-0.5-0.1-0.1-0.30.2-0.5-0.4-0.20.2
Progressive ratio test 1 breakpoint0.10.10.40.30.1-0.10.6-0.1-0.4-0.10.1-0.10.40.4-0.00.50.30.3-0.5-0.1-0.1-0.40.2-0.5-0.4-0.30.3
Progressive ratio test 1 inactive lever presses0.30.71.8-0.6-0.9-0.50.2-1.0-0.30.1-0.0-1.30.40.61.1-0.10.40.70.4-1.1-1.1-0.9-1.10.1-1.4-1.31.3
Progressive ratio test 2 active lever presses0.20.21.2-0.1-0.3-0.00.7-0.8-0.50.4-0.3-0.80.20.20.4-0.2-0.10.3-1.1-0.1-0.1-0.30.1-0.9-0.6-0.20.3
Progressive ratio test 2 breakpoint0.20.21.2-0.1-0.4-0.10.6-0.8-0.40.5-0.4-0.80.20.10.4-0.2-0.10.3-1.1-0.0-0.0-0.20.2-0.8-0.6-0.20.2
Progressive ratio test 2 inactive lever presses0.10.32.20.60.20.21.3-0.3-0.90.1-0.1-0.30.50.5-0.30.1-0.10.3-1.5-0.3-0.3-0.30.3-1.1-0.5-0.2-0.0
Incentive Sensitization - Responses0.10.42.1-0.2-0.4-0.10.3-0.9-0.30.8-0.7-0.8-0.2-0.30.1-0.7-1.0-0.3-1.00.10.10.30.6-1.40.00.6-0.4
Incentive Sensitization - Breakpoint0.20.42.0-0.2-0.5-0.10.3-1.1-0.30.9-0.8-0.9-0.2-0.30.1-0.7-1.0-0.2-1.00.10.10.30.5-1.4-0.10.5-0.4
Sum of active levers in priming session hrs 5-60.20.20.8-0.6-0.5-0.9-0.9-0.30.50.3-0.4-0.3-0.6-0.60.20.2-0.6-0.70.8-0.1-0.00.4-0.20.00.40.2-0.3
Progressive ratio0.92.76.1-0.9-0.9-2.1-1.4-0.81.51.6-1.9-0.4-1.9-1.9-0.3-1.1-2.5-2.3-0.01.61.52.21.9-0.12.22.2-2.2
Food seeking constrained by brief footshock2.93.66.9-2.5-2.5-2.0-2.2-2.62.22.5-2.4-2.5-2.2-2.12.3-2.2-1.8-1.41.61.61.51.50.50.70.70.8-0.2
Seeking ratio, punishment vs. effort0.40.82.9-0.2-0.31.00.5-0.5-0.5-0.20.5-0.80.80.81.1-0.01.21.30.4-0.6-0.6-1.2-1.3-0.1-1.6-1.51.7
Retroperitoneal fat weight20.391.1141.411.711.611.211.411.4-11.3-11.911.710.311.310.8-8.99.79.99.0-7.2-8.8-8.6-8.7-5.6-6.3-5.6-5.62.9
Reaction time number correct0.10.31.4-0.8-0.7-0.4-0.7-0.50.60.4-0.3-0.6-0.40.10.9-0.40.20.11.20.30.2-0.0-0.10.9-0.2-0.50.6
Reaction time mean minus median0.21.43.21.41.31.41.41.0-1.8-1.31.30.91.41.3-1.31.70.51.0-1.2-1.4-1.5-1.1-0.9-0.7-0.8-0.40.2
Reaction time mean minus median AUC0.21.14.71.21.20.91.11.1-1.4-1.21.11.01.10.8-1.42.20.40.4-1.2-1.1-1.1-0.7-0.7-0.3-0.30.0-0.2
Reaction time num false alarms2.23.87.8-1.0-1.0-1.6-1.5-0.92.32.1-2.2-0.3-2.3-2.20.2-2.3-2.0-2.20.12.72.82.52.81.02.42.0-2.0
Reaction time num false alarms AUC1.32.95.1-1.2-1.1-1.7-1.5-1.02.11.9-2.0-0.6-2.1-2.00.4-2.0-1.7-2.00.22.22.32.12.21.21.91.6-1.6
Reaction time trials correct on left0.10.31.4-0.8-0.7-0.4-0.7-0.50.60.4-0.3-0.6-0.40.10.9-0.40.20.11.20.30.2-0.0-0.10.9-0.2-0.50.6
Reaction time trials on left0.10.31.4-0.8-0.7-0.4-0.7-0.50.60.3-0.3-0.6-0.30.10.9-0.40.20.21.20.20.2-0.1-0.20.9-0.3-0.60.7
Reaction time mean1.32.95.81.61.31.92.10.9-2.4-1.71.80.72.22.1-0.91.31.41.8-1.6-2.1-2.2-2.0-1.8-0.8-1.8-1.51.1
Reaction time mean AUC1.02.55.01.61.41.82.01.0-2.2-1.61.70.82.01.9-1.01.31.31.6-1.6-1.9-1.9-1.7-1.5-0.8-1.5-1.20.9
Median of all reaction times1.62.54.71.41.11.72.00.8-2.2-1.51.60.52.01.9-0.51.01.51.8-1.4-1.9-2.0-1.9-1.8-0.7-1.8-1.51.2
Reaction time omissions0.40.72.00.60.61.20.60.5-1.1-1.00.90.41.00.8-0.51.40.40.8-0.4-1.3-1.4-0.8-1.0-0.2-0.7-0.50.4
Reaction time false alarm rate1.72.44.5-0.8-0.8-1.3-1.1-0.71.71.7-1.8-0.4-1.8-2.00.1-1.8-1.7-1.9-0.32.02.02.02.10.71.91.8-1.7
Reaction time premature initiation rate0.30.51.3-0.1-0.1-0.9-0.3-0.00.70.6-0.70.2-0.7-0.8-0.3-0.1-0.7-1.1-0.51.01.01.01.10.51.01.0-1.0
Reaction time premature initiations0.20.61.3-0.6-0.6-1.1-0.7-0.41.00.8-0.9-0.3-0.9-0.80.3-0.4-0.7-1.00.21.01.00.91.01.10.80.6-0.6
Std. dev. reaction times0.62.14.41.51.41.71.71.1-2.1-1.61.70.91.81.7-1.21.31.01.4-1.2-1.9-1.9-1.6-1.5-0.7-1.3-1.00.7
Reaction time trials completed0.10.31.4-0.8-0.7-0.4-0.7-0.50.60.3-0.3-0.6-0.30.10.9-0.40.20.21.20.20.2-0.1-0.20.9-0.3-0.60.7
Reaction time trials AUC0.10.31.2-0.7-0.7-0.3-0.5-0.50.50.3-0.2-0.6-0.20.20.9-0.50.30.31.10.10.1-0.2-0.20.9-0.4-0.70.8
Run reversals in cocaine runway, females0.80.92.51.41.21.31.60.9-1.3-0.80.80.91.10.9-1.10.50.70.8-1.1-0.6-0.6-0.7-0.4-1.1-0.5-0.50.0
Run reversals in cocaine runway, males1.01.23.00.40.41.40.70.5-0.8-1.01.10.21.11.30.3-1.01.61.60.1-0.9-0.9-1.4-1.10.7-1.4-1.71.6
Latency to leave start box in cocaine runway0.71.03.40.90.7-0.30.80.3-0.20.4-0.50.7-0.2-0.3-1.3-0.5-0.9-1.0-1.91.21.20.91.8-0.81.01.4-1.5
Latency to leave start box in cocaine runway, F1.11.44.61.71.60.51.41.4-0.6-0.30.31.70.30.3-2.0-0.1-0.2-0.5-2.10.91.00.61.7-0.91.11.2-1.6
Latency to leave start box in cocaine runway, M0.70.71.4-0.8-0.9-1.2-0.5-1.20.61.1-1.1-1.0-0.8-0.90.4-0.5-1.1-1.0-0.10.80.80.70.90.00.40.7-0.4
Std. dev. time between licks in bursts0.91.74.7-0.3-0.0-1.1-1.20.41.40.6-0.90.7-1.4-1.5-0.70.3-1.3-1.70.61.51.61.81.80.72.12.2-1.9
Total sessions with >9 infusions0.40.51.9-0.7-0.9-1.0-0.1-1.40.21.2-1.1-1.3-0.6-0.60.60.0-1.0-0.6-0.50.30.30.50.2-0.1-0.00.4-0.2
Short access day 1 total inactive lever presses0.10.31.00.30.2-0.40.50.10.10.4-0.40.2-0.3-0.3-0.2-0.3-0.3-0.6-1.00.60.70.50.6-0.90.50.5-0.8
Short access day 10 total inactive lever presses0.31.83.61.51.21.01.91.1-1.7-1.31.30.91.51.5-0.81.01.31.1-1.4-1.7-1.7-1.3-1.3-1.7-1.1-1.00.4
Short access day 1 total infusions1.22.44.3-1.5-1.6-1.9-1.2-1.91.42.1-2.1-1.6-1.7-1.81.0-1.2-2.0-1.9-0.11.61.61.61.5-0.51.11.5-1.1
Short access day 10 total infusions0.10.21.0-0.6-0.7-1.0-0.2-0.60.40.3-0.3-0.8-0.20.10.8-0.20.3-0.00.6-0.1-0.1-0.2-0.60.1-0.4-0.70.6
Short access total infusions0.30.41.2-0.2-0.3-0.80.1-0.60.20.8-0.8-0.4-0.5-0.5-0.0-0.1-0.8-0.8-0.70.70.70.70.9-1.10.50.7-0.7
Short access day 1 locomotion0.30.62.0-1.0-1.2-1.0-0.6-1.40.41.1-1.0-1.4-0.7-0.70.9-0.4-1.0-0.60.20.20.10.40.30.4-0.10.30.0
Short access day 10 total locomotion0.51.95.8-2.1-2.2-1.9-1.3-2.21.21.4-1.3-2.4-1.0-0.82.3-1.0-0.6-0.41.6-0.1-0.10.2-1.11.3-0.6-0.81.0
Short access total locomotion1.21.96.2-2.0-2.2-1.8-1.2-2.41.11.6-1.5-2.5-1.0-0.82.3-1.1-0.6-0.41.30.30.30.2-0.41.2-0.7-0.61.0
One hour access (0.3 mA shock)0.70.82.9-1.1-1.3-1.2-0.5-1.70.61.4-1.3-1.6-0.8-0.81.0-0.8-1.1-0.7-0.10.50.50.50.1-0.2-0.10.3-0.1
Compulsive drug intake0.60.92.0-1.2-1.1-1.0-1.4-1.01.21.1-1.1-0.9-1.2-1.10.6-1.0-1.1-1.01.30.70.71.00.00.00.70.7-0.4
One hour access (shock baseline)0.10.42.80.30.1-0.30.8-0.3-0.20.6-0.5-0.1-0.1-0.2-0.30.1-0.5-0.4-1.70.70.70.41.2-0.40.20.6-0.7
Social response proportion4.45.611.12.42.23.33.01.7-3.0-2.42.61.43.02.7-1.21.22.63.0-2.2-2.3-2.3-2.6-1.5-1.8-2.3-2.21.6
Social responses0.30.31.10.0-0.00.90.2-0.1-0.4-0.30.5-0.20.60.50.5-0.50.60.9-0.1-0.6-0.6-0.8-0.50.0-0.9-1.01.0
Social time0.61.02.00.80.61.21.40.3-1.3-0.80.90.11.21.0-0.10.31.11.2-1.4-1.1-1.2-1.2-1.3-0.6-1.2-1.20.9
Soleus weight0.10.20.70.70.70.80.60.7-0.4-0.50.40.70.40.3-0.70.20.30.3-0.7-0.0-0.0-0.10.3-0.50.10.1-0.3
Bone: stiffness0.30.52.40.91.11.00.21.40.1-0.60.61.50.10.3-1.1-0.20.50.30.00.50.60.30.80.80.80.2-0.5
Tibialis anterior weight1.13.76.92.42.32.62.52.0-2.5-2.12.21.82.32.2-1.91.91.61.9-1.8-1.7-1.7-1.7-1.1-1.9-1.2-0.90.5
Time to tail flick, vehicle, before self-admin3.44.29.63.13.02.22.63.0-2.2-2.42.23.02.01.8-3.12.41.40.9-2.5-1.0-1.0-1.00.2-1.4-0.0-0.1-0.7
Time to tail flick, vehicle, after self-admin0.20.41.20.91.00.60.61.1-0.6-0.90.81.00.60.8-1.00.10.50.3-0.3-0.6-0.6-0.4-0.30.3-0.0-0.2-0.1
Time to tail flick, test, before self-admin0.40.41.7-0.2-0.3-0.7-0.2-0.50.30.6-0.6-0.3-0.5-0.70.20.9-0.7-0.8-0.50.80.70.61.31.30.40.7-0.4
Time to tail flick, test, after self-admin0.20.31.5-0.1-0.2-1.2-0.1-0.10.50.4-0.5-0.0-0.5-0.60.1-0.3-0.2-0.9-0.50.40.40.60.60.60.60.2-0.6
Delta time to tail flick, vehicle, before/after SA1.01.12.9-1.5-1.4-1.4-1.5-1.21.21.0-1.0-1.2-1.1-0.81.4-1.1-0.7-0.71.70.30.30.6-0.31.20.30.20.2
Delta time to tail flick, test, before/after SA0.20.22.0-0.1-0.1-0.20.10.0-0.0-0.20.2-0.10.20.40.2-1.40.50.20.2-0.6-0.6-0.3-1.0-0.4-0.4-0.90.4
Tibia length3.08.425.94.54.73.63.34.8-2.3-3.02.85.12.22.1-4.82.51.91.3-3.3-0.3-0.1-0.51.5-1.71.10.8-1.8
Ambulatory time before self-admin0.51.54.20.40.31.10.80.1-1.5-1.01.2-0.21.41.30.00.70.81.40.0-2.0-2.0-1.6-2.1-0.0-1.6-1.51.4
Ambulatory time after self-admin0.30.52.0-1.0-0.7-0.6-1.4-0.41.10.4-0.5-0.4-0.8-0.80.7-1.0-0.4-0.51.40.80.80.50.20.40.50.20.0
Bone: tissue strength0.20.20.90.60.61.00.60.4-0.5-0.20.40.60.40.5-0.60.00.20.6-0.20.10.1-0.20.3-0.8-0.2-0.20.2
Total heroin consumption0.20.33.30.1-0.0-0.30.4-0.2-0.6-0.10.1-0.20.30.2-0.31.8-0.2-0.1-0.4-0.5-0.5-0.3-0.6-0.7-0.4-0.30.1
Bone: trabecular number0.71.34.00.30.4-0.6-0.20.40.70.7-0.80.8-1.0-1.2-1.20.4-1.2-1.5-0.81.31.31.51.70.51.82.0-2.0
Bone: trabecular spacing1.31.94.10.80.81.30.81.1-1.1-1.71.80.71.51.80.20.42.01.90.6-1.6-1.5-1.8-1.5-0.2-1.6-2.01.7
Bone: trabecular thickness1.11.65.00.80.8-0.50.40.70.10.1-0.41.1-0.5-1.1-1.61.7-1.0-1.6-2.21.11.11.21.6-0.21.62.2-2.2
Bone: trabecular tissue density0.20.32.20.70.70.40.70.6-0.6-0.60.60.60.60.5-0.60.50.50.4-0.7-0.3-0.2-0.40.1-1.5-0.2-0.00.0
Water consumed over 24 hours0.00.10.3-0.1-0.2-0.10.0-0.30.20.4-0.3-0.2-0.2-0.20.1-0.5-0.2-0.2-0.30.50.50.20.40.40.1-0.10.0
Number of responses in last shaping day1.11.42.6-1.3-1.4-1.3-1.1-1.51.21.6-1.6-1.3-1.4-1.40.8-0.8-1.4-1.20.31.31.31.21.20.90.80.8-0.6