Hub : Genes

Kif16b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA XM_063283799.1 0.02 0.02 3.3e-03 0.02 0.02 0.01 0.02 3.7e-03 2.3e-03 2.7e-02 3.3e-03
2 NAcc alternative polyA XM_063283799.1 0.03 0.02 1.1e-04 0.02 0.03 0.02 0.02 9.8e-04 7.6e-05 3.5e-04 2.6e-04
3 Liver gene expression Kif16b 0.22 0.09 0.0e+00 0.19 0.18 0.18 0.18 1.8e-20 2.1e-19 8.4e-20 8.9e-20
4 IC gene expression Kif16b 0.11 0.08 3.4e-03 0 0.04 0.02 0.02 2.7e-01 1.4e-02 4.1e-02 5.1e-02
5 NAcc gene expression Kif16b 0.07 0.03 4.2e-09 0.03 0.05 0.04 0.04 7.0e-06 7.3e-08 1.3e-06 2.8e-07
6 Liver alternative polyA XM_063283800.1 0.09 0.06 1.6e-09 0.06 0.07 0.07 0.06 2.4e-07 4.5e-08 4.5e-08 4.3e-07
7 Liver isoform ratio XM_039105044.2 0.05 0.04 1.3e-03 0.01 0.01 0.01 0.01 3.2e-02 1.7e-02 5.1e-02 3.7e-02
8 BLA gene expression Kif16b 0.07 0.05 1.8e-03 0.02 0.04 0.03 0.03 2.7e-02 3.9e-03 1.5e-02 1.5e-02
9 PL gene expression Kif16b 0.03 0.02 7.6e-03 0.01 0.01 0.01 0 3.2e-02 8.0e-03 1.7e-02 2.5e-01
10 Liver isoform ratio XM_063283798.1 0.02 0.01 3.7e-03 0.01 0.02 0 0.01 2.2e-02 5.0e-03 1.7e-01 4.6e-02
11 RMTg intron excision ratio chr3_150516570_150516904 0.1 0.07 8.9e-03 0.05 0.06 0.06 0.04 2.3e-02 1.3e-02 9.2e-03 4.0e-02
12 Adipose alternative polyA XM_063283799.1 0.07 0.04 2.4e-06 0.04 0.03 0.03 0.03 5.4e-05 6.5e-04 4.6e-04 4.3e-04
13 Liver mRNA stability Kif16b 0.12 0.06 1.3e-05 0.02 0.03 0.04 0.03 1.1e-03 1.0e-04 3.1e-05 1.0e-04
14 IC isoform ratio XM_063283800.1 0.12 0.1 9.6e-03 -0 0.01 0.01 0.01 5.5e-01 1.0e-01 1.1e-01 1.7e-01
15 Liver intron excision ratio chr3_150675218_150707483 0.04 0.03 2.2e-04 0.02 0.02 0.02 0.02 3.9e-03 1.5e-03 4.7e-03 1.4e-03
16 Brain gene expression Kif16b 0.21 0.11 3.8e-09 0.06 0.1 0.12 0.11 1.1e-06 6.7e-10 1.1e-11 1.6e-10
17 BLA alternative polyA XM_006235113.5 0.05 0.04 6.2e-03 0.02 0.02 0.03 0.02 2.4e-02 2.6e-02 1.6e-02 3.8e-02
18 LHb mRNA stability Kif16b 0.12 0.08 5.5e-03 0.06 0.1 0.05 0.06 1.7e-02 2.9e-03 2.5e-02 2.0e-02
19 Liver intron excision ratio chr3_150501111_150502367 0.03 0.02 3.9e-03 0.01 0.01 0 0 1.6e-02 1.8e-02 2.9e-01 1.1e-01
20 Liver intron excision ratio chr3_150489254_150502367 0.03 0.02 3.2e-03 0.01 0.01 0 0.01 1.3e-02 1.1e-02 2.6e-01 6.4e-02
21 Adipose gene expression Kif16b 0.78 0.06 0.0e+00 0.58 0.6 0.6 0.59 8.8e-79 2.6e-82 9.2e-83 2.3e-80
22 Liver alternative polyA XM_063283799.1 0.18 0.08 0.0e+00 0.15 0.15 0.16 0.15 7.0e-16 8.4e-17 1.4e-17 3.5e-16
23 Adipose mRNA stability Kif16b 0.5 0.12 0.0e+00 0.28 0.29 0.27 0.28 8.8e-32 2.2e-32 5.0e-30 1.0e-31

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.71.13.30.40.40.60.10.30.60.7-0.80.7-0.91.01.1-0.2-1.0-1.31.2-1.41.4-1.71.6-1.8-0.2-1.8
Area under the delay curve0.30.31.9-0.7-0.7-0.2-0.2-1.00.10.4-0.3-1.10.00.1-1.40.70.10.40.0-0.2-0.30.2-0.70.5-0.00.7
BMI with tail9.934.354.37.16.9-6.77.46.5-7.1-7.06.95.87.0-6.95.2-5.26.25.75.25.3-5.53.6-3.83.74.02.0
BMI without tail8.425.638.55.55.3-6.26.04.9-6.1-5.96.04.26.2-6.13.5-4.05.65.63.65.3-5.34.4-4.24.03.32.8
Body weight11.951.992.19.59.6-9.08.79.5-8.2-8.88.59.08.0-7.68.0-7.46.86.26.45.4-5.42.4-2.72.64.70.6
Weight adjusted by age0.30.42.30.60.8-0.7-0.01.1-0.3-1.00.91.00.4-0.20.7-1.50.50.2-0.40.8-0.30.50.1-0.0-0.7-0.1
Bone surface0.20.32.30.60.5-0.30.80.1-0.40.2-0.20.30.10.00.80.1-0.3-0.21.5-0.10.3-0.40.3-0.50.8-0.7
Bone volume0.30.51.70.60.5-0.10.50.30.10.5-0.50.6-0.40.41.00.4-0.6-0.61.3-0.80.8-1.10.9-1.00.0-1.2
Breakpoint value in progressive ratio session0.40.52.00.1-0.1-0.30.6-0.5-0.9-0.10.2-0.50.6-0.50.2-1.4-0.10.40.60.9-0.61.3-0.90.51.10.5
Number of licking bursts0.30.51.30.30.50.2-0.20.70.5-0.0-0.10.9-0.40.40.8-0.6-0.3-0.80.4-0.90.8-1.21.1-1.1-0.3-1.1
Context. condit. distance diff. score0.30.30.9-0.8-0.70.7-0.9-0.50.70.4-0.4-0.6-0.50.4-0.80.6-0.2-0.3-1.0-0.40.2-0.30.10.1-0.80.2
Locomotion velocity, session 11.81.94.7-2.0-2.11.2-1.4-2.11.41.7-1.6-2.2-1.31.2-2.11.8-0.8-0.6-1.0-0.80.60.2-0.20.4-1.50.6
Locomotion distance, session 14.35.59.5-3.0-3.03.1-2.8-2.92.72.8-2.8-2.7-2.72.7-2.42.2-2.2-2.3-1.5-1.91.9-1.01.1-1.1-1.7-0.5
Locomotion velocity, session 22.22.55.1-2.2-2.21.7-1.8-2.31.72.0-1.9-2.2-1.71.6-1.92.0-1.4-1.2-1.2-1.01.1-0.10.4-0.3-1.10.1
Locomotion distance, session 25.17.114.9-3.6-3.72.8-3.0-3.92.93.4-3.2-3.7-2.82.6-3.23.5-2.4-1.8-2.2-1.81.7-0.50.5-0.4-1.60.3
Locomotion velocity, session 33.23.67.5-2.4-2.22.3-2.6-1.72.71.9-2.0-1.7-2.32.0-2.02.1-1.2-1.6-2.1-1.81.6-0.91.2-0.7-2.1-0.3
Locomotion distance, session 31.11.22.4-1.4-1.31.4-1.4-1.01.51.1-1.2-1.0-1.31.1-1.11.3-0.7-0.9-1.2-1.10.9-0.50.7-0.5-1.3-0.2
Stereotopy head waving bouts, day 30.50.62.40.90.9-0.40.50.7-0.20.0-0.11.0-0.10.31.5-0.5-0.7-0.51.1-0.60.7-0.91.0-1.20.7-1.3
Stereotopy head waving duration, day 30.10.10.60.50.5-0.50.50.3-0.4-0.00.10.40.2-0.10.8-0.2-0.30.10.60.00.1-0.10.2-0.30.6-0.4
Locomotion velocity, session 71.82.03.9-1.5-1.31.2-2.0-1.01.91.5-1.5-0.8-1.81.4-0.81.6-1.3-1.1-1.8-1.71.5-1.31.3-0.8-1.4-0.5
Locomotion distance, session 71.11.43.8-1.3-1.10.8-1.5-0.81.71.2-1.1-0.7-1.41.0-0.92.0-0.6-0.5-1.8-1.51.0-1.20.8-0.2-1.9-0.0
Stereotopy head waving bouts, day 70.50.61.00.90.9-0.90.71.0-0.8-1.01.00.90.9-0.90.6-0.60.90.80.30.9-0.70.8-0.50.60.20.4
Stereotopy head waving duration, day 70.10.10.30.40.4-0.10.40.4-0.2-0.10.10.40.1-0.10.4-0.40.1-0.10.50.00.1-0.00.2-0.20.4-0.4
Locomotion velocity, session 81.31.63.8-1.8-1.91.5-1.5-1.91.21.5-1.4-1.9-1.21.1-1.71.4-1.1-0.8-1.2-0.70.60.1-0.00.0-0.90.4
Locomotion distance, session 84.36.211.9-3.4-3.42.9-3.2-3.13.02.7-2.6-3.1-2.62.2-3.23.2-1.7-1.6-2.9-1.71.5-0.60.6-0.1-2.40.5
Degree of sensitization distance0.10.21.00.40.5-1.00.30.4-0.3-0.20.30.50.3-0.40.50.20.10.7-0.0-0.1-0.1-0.4-0.00.3-0.40.2
Degree of sensitization stereotypy0.70.81.90.40.5-0.70.50.6-0.8-1.11.10.31.0-1.1-0.1-0.71.21.0-0.41.4-1.11.4-1.01.2-0.31.0
Conditioned locomotion0.91.03.40.80.9-0.90.30.80.30.4-0.41.3-0.50.61.60.5-0.8-0.30.8-1.61.2-1.81.5-1.20.2-1.5
Cocaine response after cond. corrected1.61.93.8-1.5-1.41.3-1.6-1.21.81.7-1.6-1.0-1.71.4-0.81.9-1.4-1.2-1.3-1.61.4-1.31.1-0.7-0.8-0.5
Cocaine response after cond. not corrected2.42.95.1-1.3-1.31.6-1.7-1.22.12.1-2.0-0.7-2.11.9-0.32.2-2.0-1.8-1.1-2.32.1-2.01.9-1.5-0.3-1.4
Cocaine response before conditioning0.40.51.50.40.40.10.20.30.20.5-0.50.5-0.40.50.90.5-0.8-0.70.7-0.80.9-0.81.0-1.11.1-1.2
Saline control response0.10.10.60.30.2-0.70.5-0.2-0.50.4-0.1-0.00.2-0.30.40.8-0.50.40.4-0.20.0-0.3-0.10.30.20.1
Bone: connectivity density1.11.74.8-0.1-0.21.3-0.3-0.40.91.3-1.40.1-1.31.60.7-0.2-1.6-2.01.2-1.61.8-1.71.8-2.20.1-2.1
Bone: cortical apparent density0.10.10.3-0.1-0.00.6-0.50.30.5-0.0-0.10.3-0.40.40.1-0.1-0.0-0.5-0.4-0.30.4-0.30.5-0.50.0-0.4
Bone: cortical area0.91.45.41.71.8-0.70.92.1-0.2-1.00.82.30.3-0.22.0-0.50.5-0.31.3-0.70.5-1.41.2-1.00.7-1.4
Bone: cortical porosity0.70.82.31.41.4-0.71.21.2-0.7-0.70.61.30.6-0.21.5-0.90.3-0.11.4-0.00.1-0.40.5-0.80.6-1.0
Bone: cortical porosity0.91.02.61.61.6-1.01.31.5-0.9-1.00.91.60.8-0.61.5-0.90.70.31.40.2-0.2-0.20.3-0.40.6-0.7
Bone: cortical thickness1.72.89.12.02.3-0.40.82.60.1-1.00.63.0-0.00.42.7-0.90.3-1.11.8-1.31.1-2.22.2-2.11.0-2.5
Bone: cortical thickness1.11.34.00.30.50.8-0.61.01.1-0.1-0.41.2-0.91.41.0-0.6-0.4-1.70.5-1.11.4-1.52.0-2.0-0.8-2.0
Bone: cortical tissue density0.10.10.4-0.2-0.10.6-0.60.20.5-0.0-0.10.1-0.40.4-0.1-0.1-0.1-0.5-0.5-0.20.3-0.20.4-0.4-0.1-0.3
Condit. Reinf. active minus inactive responses0.40.41.80.80.9-0.60.40.9-0.3-0.30.31.10.10.01.3-0.2-0.4-0.10.3-0.20.4-0.50.7-0.81.0-0.9
Condit. Reinf. active-inactive response ratio0.20.31.10.70.8-0.60.30.8-0.3-0.30.30.90.1-0.01.10.0-0.20.0-0.0-0.10.2-0.50.5-0.50.7-0.6
Condit. Reinf. active responses0.10.10.30.10.3-0.3-0.20.3-0.2-0.30.20.40.10.10.4-0.3-0.3-0.0-0.50.20.00.20.2-0.30.6-0.2
Condit. Reinf. inactive responses0.30.41.3-0.6-0.6-0.0-0.4-0.6-0.2-0.10.2-0.80.2-0.2-0.9-0.10.10.5-0.90.7-0.61.1-0.80.8-0.21.0
Incentive salience index mean0.10.10.50.00.10.1-0.30.10.00.1-0.10.2-0.20.40.4-0.2-0.6-0.4-0.2-0.20.4-0.30.5-0.60.7-0.5
Condit. Reinf. lever presses0.20.30.9-0.5-0.50.4-0.3-0.5-0.3-0.30.3-0.70.3-0.2-0.9-0.60.20.2-0.60.8-0.71.0-0.80.60.30.8
Condit. Reinf. active minus inactive responses0.40.53.20.60.5-1.80.90.1-0.80.00.30.20.6-0.90.51.40.11.4-0.20.3-0.40.2-0.60.90.00.6
Condit. Reinf. active-inactive response ratio0.50.52.00.40.3-1.40.8-0.0-0.7-0.20.4-0.10.7-0.90.01.10.51.30.10.6-0.70.5-0.91.2-0.20.9
Condit. Reinf. active responses0.60.82.80.50.4-1.70.70.2-1.0-0.40.70.10.9-1.20.10.80.51.7-0.60.9-0.90.8-1.01.2-0.11.1
Condit. Reinf. inactive responses0.20.30.90.60.6-0.50.40.6-0.8-0.70.70.50.6-0.70.5-0.90.30.5-0.30.8-0.50.6-0.30.10.40.1
Condit. Reinf. lever presses1.82.56.10.60.3-2.01.7-0.3-2.0-0.81.2-0.61.9-2.0-0.40.41.22.40.52.0-2.11.9-2.52.30.12.1
Condit. Reinf. lever reinforcers received0.70.93.20.40.3-1.80.9-0.2-1.2-0.20.6-0.21.0-1.30.01.00.41.8-0.41.0-1.10.9-1.31.40.11.2
Conditioned reinforcement - actives1.42.45.5-1.5-1.92.3-0.6-2.31.32.3-2.3-2.1-1.61.4-1.51.3-1.6-1.60.4-1.61.3-1.20.5-0.8-0.3-0.6
Conditioned reinforcement - inactives0.91.32.8-0.8-1.01.5-0.7-1.01.01.3-1.4-0.8-1.21.2-0.40.9-1.4-1.50.2-1.31.3-1.71.0-1.2-0.0-1.0
Conditioned locomotion2.43.26.0-2.0-2.22.1-1.6-2.41.82.4-2.4-2.2-2.02.0-1.72.2-2.0-1.7-0.9-1.61.6-1.10.9-1.10.0-0.6
Patch foraging indifference point 0 sec0.20.30.8-0.7-0.70.9-0.9-0.70.50.6-0.6-0.6-0.70.5-0.20.3-0.9-0.7-0.6-0.20.5-0.40.4-0.5-0.2-0.2
Patch foraging indifference point AUC1.01.53.8-1.8-1.61.2-2.0-1.41.51.2-1.2-1.4-1.41.6-1.30.6-1.2-1.1-1.5-0.70.9-0.30.6-0.7-0.6-0.1
Delay disc. indifference point, 0s delay0.40.41.20.30.1-1.00.8-0.2-0.9-0.30.5-0.30.8-0.7-0.50.50.60.90.70.5-0.90.2-1.10.80.30.8
Delay disc. indifference point, 16s delay0.70.71.4-1.0-1.00.7-0.9-1.20.81.1-1.1-1.1-0.91.1-1.01.0-1.0-0.7-0.4-0.90.7-0.20.4-0.60.4-0.3
Delay disc. indifference point, 2s delay1.01.13.40.30.1-1.21.2-0.4-1.3-0.50.7-0.71.3-1.2-0.7-0.11.21.60.51.1-1.51.0-1.81.50.11.6
Delay disc. indifference point, 24s delay0.91.02.4-1.1-1.01.2-1.2-0.61.50.9-1.0-0.6-1.21.2-1.31.6-0.2-0.9-0.6-1.40.9-0.80.7-0.4-0.2-0.3
Delay disc. indifference point, 4s delay0.70.81.80.30.4-1.00.30.6-0.6-1.11.10.20.9-1.0-0.4-0.21.31.3-0.80.9-1.11.2-1.01.2-0.61.1
Delay disc. indifference point, 8s delay0.50.63.6-1.0-1.10.2-0.5-1.20.60.7-0.6-1.3-0.40.3-1.91.10.10.3-0.1-0.5-0.1-0.1-0.50.4-0.40.7
Indifference point function ln k0.30.51.81.11.0-0.41.21.0-0.6-0.60.51.00.6-0.70.9-1.00.60.31.3-0.0-0.2-0.30.1-0.1-0.2-0.4
Indifference point function log k0.30.51.81.11.0-0.41.21.0-0.6-0.60.51.00.6-0.70.9-1.00.60.31.3-0.0-0.2-0.30.1-0.1-0.2-0.4
Patch foraging total patch changes 0 sec0.40.71.5-1.2-1.21.2-1.2-1.10.80.9-0.9-1.1-0.90.7-0.70.5-1.1-0.8-1.0-0.30.6-0.30.3-0.4-0.5-0.0
Patch foraging total patch changes 12 sec0.10.10.4-0.3-0.2-0.3-0.3-0.2-0.2-0.20.3-0.30.2-0.2-0.3-0.10.10.4-0.60.5-0.40.3-0.50.5-0.10.6
Patch foraging total patch changes 18 sec1.42.16.2-2.1-2.01.5-2.2-2.01.41.5-1.4-2.0-1.41.2-1.71.6-1.5-0.9-2.5-0.40.70.10.10.1-0.80.5
Patch foraging total patch changes 24 sec0.50.82.6-1.3-1.30.7-1.2-1.40.60.9-0.8-1.4-0.70.7-1.11.0-0.9-0.4-1.6-0.20.20.5-0.20.2-0.20.6
Patch foraging total patch changes 6 sec0.30.41.6-0.9-0.80.9-1.2-0.60.50.4-0.4-0.6-0.60.4-0.30.3-0.8-0.6-1.30.10.3-0.10.2-0.3-0.40.1
Patch foraging time to switch 0 sec1.22.44.82.22.2-1.82.12.0-1.9-1.71.82.01.7-1.71.9-0.81.31.21.41.1-1.10.6-0.60.51.00.0
Patch foraging water rate 0 sec1.32.86.9-2.6-2.51.8-2.5-2.21.91.6-1.6-2.4-1.61.6-2.51.1-1.0-1.0-2.0-0.80.7-0.10.10.0-1.10.7
Patch foraging water rate 12 sec1.42.95.8-2.3-2.22.1-2.4-1.72.41.7-1.8-1.7-2.01.7-2.12.0-1.0-1.2-1.9-1.51.3-0.70.8-0.6-0.7-0.1
Patch foraging water rate 18 sec3.35.211.0-2.6-2.43.0-3.2-1.73.32.2-2.4-1.5-2.92.5-1.91.8-1.7-2.3-2.3-2.72.3-1.92.0-1.5-1.8-0.9
Patch foraging water rate 24 sec2.33.28.5-2.4-2.11.9-2.9-1.32.91.4-1.5-1.3-2.21.8-2.11.6-0.7-1.2-2.6-1.51.4-0.71.1-0.4-2.40.1
Patch foraging water rate 6 sec1.62.34.4-1.2-1.01.6-2.0-0.52.11.3-1.5-0.2-2.01.9-0.51.0-1.5-1.7-1.4-2.01.9-1.82.0-1.7-0.3-1.4
Seeking ratio, delayed vs. immediate footshock0.30.31.40.80.7-0.60.90.6-0.5-0.40.40.70.5-0.60.70.90.40.31.20.0-0.2-0.2-0.00.30.3-0.2
Distance traveled before self-admin1.41.85.60.20.1-1.20.7-0.1-1.5-1.11.2-0.51.5-1.5-0.5-0.71.11.8-0.32.1-1.92.4-2.11.9-0.01.9
Distance traveled after self-admin0.20.31.0-0.8-0.70.5-1.0-0.50.70.4-0.4-0.5-0.60.7-0.60.5-0.4-0.4-0.9-0.50.30.00.2-0.20.10.1
Extensor digitorum longus weight0.31.12.21.00.9-1.51.20.9-1.2-1.31.20.71.3-1.20.4-0.81.31.21.00.9-1.20.7-1.00.90.20.7
Bone: elastic displacement0.20.20.70.70.7-0.60.60.7-0.4-0.50.50.70.4-0.10.7-0.60.40.10.80.2-0.2-0.10.1-0.20.3-0.3
Bone: elastic work2.33.05.52.32.3-1.92.22.2-2.0-2.12.02.02.0-1.61.9-1.61.81.22.31.3-1.40.6-0.70.51.20.1
Bone: endosteal estimation1.32.95.91.51.3-2.42.20.8-2.2-1.41.60.62.1-2.30.7-0.41.62.41.41.7-2.01.6-2.02.10.91.5
Bone: endosteal perimeter0.20.51.70.30.1-1.00.8-0.2-0.8-0.00.3-0.30.7-1.0-0.00.90.41.20.30.4-0.80.5-1.01.30.11.0
Epididymis fat weight8.930.553.37.37.3-7.06.96.9-6.4-6.56.46.66.2-5.96.0-5.45.24.95.34.2-4.31.7-2.42.23.90.7
Delta time in closed arm before/after self-admin0.30.31.1-0.5-0.40.7-0.7-0.30.40.4-0.4-0.3-0.50.5-0.10.6-0.8-0.7-0.60.10.50.20.5-0.51.1-0.5
Delta time in open arm before/after self-admin1.51.43.61.71.8-1.71.21.9-1.1-1.51.41.91.1-1.11.6-1.51.00.70.90.5-0.6-0.30.0-0.00.1-0.2
Diff in mean of infusions in LGA sessions0.70.93.3-0.1-0.2-0.70.4-0.5-0.9-0.40.6-0.70.9-0.9-0.60.10.61.0-0.51.6-1.21.8-1.51.31.41.3
Delay discount exponential model param0.30.32.00.80.8-0.00.41.0-0.3-0.50.41.00.2-0.31.4-0.7-0.1-0.30.20.40.2-0.10.5-0.30.2-0.6
Extinction: sum of active levers before priming0.30.31.2-0.6-0.70.3-0.3-0.8-0.10.3-0.2-0.90.00.1-0.50.2-0.30.1-0.50.7-0.31.1-0.60.60.80.5
Active lever presses in extinction session 60.70.73.71.31.1-0.81.60.6-1.1-0.40.40.70.8-0.81.3-1.20.30.31.90.1-0.3-0.2-0.2-0.20.4-0.4
Bone: final force0.71.14.21.41.6-1.30.82.0-0.4-1.31.22.00.7-0.71.5-0.21.20.50.6-0.0-0.2-0.50.50.0-0.2-0.4
Bone: final moment0.61.04.21.41.6-1.10.72.0-0.3-1.21.12.00.6-0.51.6-0.21.00.20.7-0.2-0.0-0.70.6-0.2-0.1-0.6
Food consumed during 24 hour testing period0.91.23.21.31.4-0.10.81.40.0-0.20.11.7-0.10.21.7-0.7-0.1-0.81.7-1.20.9-1.81.4-1.40.1-1.7
Glucose1.52.34.61.81.8-2.11.81.7-1.9-1.81.81.61.8-1.91.4-1.61.41.51.41.3-1.40.6-1.01.00.60.6
Heart weight1.32.04.01.91.8-1.82.01.5-1.7-1.31.51.51.6-1.71.4-0.51.31.41.40.8-1.10.6-0.80.91.80.4
Delay discount hyperbolic model param0.20.21.20.40.40.30.00.60.1-0.10.00.7-0.20.11.1-0.3-0.4-0.5-0.00.10.4-0.20.7-0.50.1-0.7
Intermittent access intake day 1-15 change0.40.72.70.0-0.40.11.2-1.1-1.00.3-0.1-1.10.7-0.6-0.50.20.20.71.70.6-0.80.7-1.40.91.60.8
Intermittent access intake escalation0.40.73.4-0.1-0.50.21.1-1.2-0.80.5-0.2-1.20.6-0.5-0.70.50.20.71.80.4-0.80.4-1.41.01.30.9
Intermittent access intake escalation 21.01.14.50.60.2-0.41.7-0.5-1.4-0.20.5-0.61.2-1.2-0.2-0.40.81.12.11.0-1.30.7-1.71.21.01.1
Intermitt. access day 1 inactive lever presses0.20.94.01.00.7-0.31.40.3-1.6-0.70.70.31.1-0.91.0-0.7-0.00.11.31.5-0.70.9-0.70.32.0-0.1
Intermitt. access day 15 inactive lever presses0.51.16.31.31.10.41.50.8-0.9-0.30.11.00.4-0.51.7-0.2-0.3-0.71.70.10.3-0.90.5-0.72.5-1.3
Intermitt. access escalation Index0.40.61.41.11.1-1.00.91.0-0.7-0.60.61.10.6-0.51.2-0.80.30.31.10.1-0.1-0.20.2-0.31.0-0.5
Intermittent access day 1 total infusions0.20.31.00.70.7-0.10.60.80.1-0.30.20.90.1-0.20.40.10.70.00.4-0.80.2-1.00.4-0.20.6-0.4
Intermittent access day 15 total infusions0.30.43.40.70.50.01.20.2-0.40.1-0.00.30.3-0.40.30.00.60.21.8-0.7-0.1-1.0-0.10.01.2-0.2
Intermittent access terminal intake (last 3 days)0.50.63.91.10.9-0.21.40.6-0.7-0.30.30.70.6-0.60.6-0.80.60.32.0-0.3-0.2-0.9-0.1-0.11.1-0.3
Intermittent access total infusions0.50.52.61.00.9-0.01.10.7-0.3-0.20.10.90.2-0.20.8-0.40.3-0.21.6-0.80.2-1.40.4-0.51.0-0.7
Intermittent access day 1 locomotion0.20.31.7-0.4-0.50.50.1-0.60.70.7-0.7-0.5-0.40.3-0.81.30.3-0.00.1-1.10.3-0.80.00.20.10.2
Intermittent access day 15 total locomotion0.71.24.20.1-0.10.90.2-0.50.41.2-1.2-0.1-0.81.00.50.7-1.3-1.31.5-1.61.3-2.01.1-1.51.5-1.5
Intermittent access total locomotion0.91.12.4-1.0-1.11.4-0.6-1.21.21.4-1.4-1.0-1.11.0-1.01.6-0.7-0.90.0-1.40.9-1.30.5-0.5-0.1-0.4
Intermittent access standard deviation0.20.41.9-0.6-0.90.70.0-1.40.01.1-0.9-1.3-0.40.5-0.60.5-0.9-0.40.7-0.30.2-0.3-0.3-0.20.40.1
Left kidney weight1.36.112.83.63.5-2.93.53.1-2.9-2.42.43.12.5-2.43.3-2.61.71.73.01.4-1.40.2-0.50.32.5-0.4
Right kidney weight0.62.75.92.42.3-2.02.31.9-1.9-1.41.52.11.6-1.42.2-1.60.91.12.20.8-0.8-0.1-0.20.02.2-0.4
Cocaine induced anxiety0.30.41.2-0.6-0.6-0.0-0.3-0.60.30.2-0.1-0.80.0-0.2-1.10.70.70.7-0.70.1-0.50.5-0.81.0-0.41.1
Post-drug Anxiety1.82.04.80.91.1-1.60.81.4-1.0-1.81.81.01.5-1.70.1-1.12.21.9-0.71.5-1.61.3-1.31.7-0.91.5
Baseline Anxiety2.83.36.72.12.3-2.41.42.5-2.0-2.62.52.32.0-1.81.7-2.61.51.50.02.0-1.51.1-0.70.7-0.10.4
Tail length0.51.95.71.92.1-2.21.12.3-1.0-1.61.52.41.0-0.72.1-2.00.70.70.90.4-0.3-0.40.5-0.60.3-0.7
Length with tail2.310.123.04.64.7-4.43.64.7-3.2-3.73.54.83.0-2.64.4-3.72.22.13.11.6-1.4-0.20.1-0.21.9-1.0
Length without tail2.99.223.04.64.6-3.43.84.6-2.9-3.12.84.82.6-2.34.7-3.11.81.33.80.7-0.8-1.40.7-0.71.9-1.7
Times rat made contact with spout0.80.92.00.70.6-1.11.20.2-1.4-0.80.90.01.2-1.00.2-0.90.71.01.01.2-1.21.0-1.21.00.30.8
Lifetime Intake0.30.41.60.50.40.40.60.10.00.3-0.40.3-0.20.20.5-0.1-0.2-0.51.3-0.80.5-1.20.5-0.71.1-0.8
Liver weight, left2.03.35.91.81.9-2.11.82.0-2.0-2.42.41.72.2-2.41.1-1.42.32.10.62.0-2.01.0-1.51.80.71.4
Liver weight, right2.03.46.92.62.6-2.62.32.4-2.2-2.02.02.41.9-1.82.4-2.41.11.51.91.2-1.1-0.0-0.30.30.5-0.2
Locomotor activity1.01.54.1-0.0-0.3-0.80.8-0.5-1.1-0.70.9-0.81.2-1.2-1.10.21.31.60.31.6-1.71.7-2.02.01.41.9
Locomotor testing distance0.40.72.4-0.9-1.10.5-0.1-1.40.10.5-0.4-1.50.00.1-1.51.30.20.20.10.5-0.61.1-1.11.10.81.1
Locomotor testing rearing0.20.41.6-0.6-0.90.60.1-1.2-0.20.6-0.5-1.3-0.00.2-0.90.6-0.3-0.20.60.3-0.30.3-0.70.51.00.5
Locomotion in novel chamber1.01.22.7-0.6-0.51.4-1.2-0.11.40.8-1.00.2-1.41.20.30.4-1.1-1.6-0.4-1.31.5-1.61.6-1.3-0.3-1.3
Locomotion in novel chamber post-restriction2.23.69.3-1.1-1.11.9-1.4-1.21.52.0-2.2-0.7-2.12.60.3-0.4-3.0-2.60.3-1.92.5-2.02.3-2.90.7-2.5
Fecal boli incidents, locomotor time 10.60.92.9-1.2-1.20.7-1.0-0.91.10.6-0.5-1.1-0.60.4-1.71.30.30.1-1.4-0.10.01.1-0.31.0-1.51.0
Change in fecal boli incidents, locomotor task1.41.44.00.80.90.40.10.8-0.00.1-0.31.2-0.50.61.8-1.7-1.3-1.30.6-1.01.2-1.51.6-2.01.5-2.0
Time >=10cm from walls, locomotor time 10.10.10.40.20.20.10.00.20.10.2-0.20.3-0.20.30.3-0.1-0.4-0.40.2-0.10.5-0.30.6-0.60.6-0.7
Bouts of movement, locomotor time 10.60.72.6-1.0-1.00.6-0.7-1.11.01.1-1.1-1.0-0.90.8-1.21.6-0.6-0.4-0.5-0.60.60.30.3-0.0-1.2-0.1
Total resting periods, locomotor time 10.91.02.9-1.2-1.30.8-1.0-1.31.21.3-1.3-1.2-1.11.0-1.21.7-0.9-0.6-0.8-0.60.80.30.4-0.1-1.1-0.2
Rest time, locomotor task time 10.10.10.3-0.4-0.50.2-0.3-0.50.30.6-0.5-0.5-0.40.4-0.40.1-0.5-0.20.1-0.40.30.00.1-0.0-0.5-0.1
Distance moved, locomotor task time 10.20.41.2-0.3-0.20.8-0.6-0.00.70.3-0.40.0-0.60.6-0.01.1-0.3-0.8-0.6-0.70.6-1.00.7-0.9-0.0-0.6
Vertical activity count, locomotor time 10.20.41.11.01.0-0.20.80.9-0.6-0.50.40.90.4-0.41.1-0.10.2-0.21.00.1-0.0-0.60.3-0.70.8-0.7
Time >=10cm from walls, locomotor time 21.62.46.72.22.0-1.42.11.7-1.9-1.31.21.81.4-1.12.1-2.40.40.52.61.0-0.60.5-0.1-0.42.3-0.8
Bouts of movement, locomotor time 20.91.44.4-0.6-0.7-0.80.1-0.8-0.6-0.30.5-1.20.8-1.0-1.5-0.30.91.7-1.01.4-1.42.1-1.81.9-0.42.0
Total resting periods, locomotor time 21.01.75.4-0.5-0.6-0.80.2-0.6-0.7-0.50.7-1.11.0-1.2-1.5-0.41.11.8-1.01.6-1.62.3-2.02.1-0.52.2
Rest time, locomotor task time 21.01.25.2-0.6-0.5-0.3-0.4-0.10.1-0.60.6-0.60.5-0.8-1.4-0.21.31.3-1.20.9-1.11.5-1.31.9-2.31.8
Distance moved, locomotor task time 21.41.64.1-0.2-0.30.9-0.3-0.70.71.4-1.4-0.2-1.11.50.71.2-1.8-1.70.7-1.51.6-1.81.5-2.01.2-1.8
Vertical activity count, locomotor time 20.60.82.30.30.1-0.10.4-0.4-0.00.8-0.80.0-0.40.80.71.1-1.1-0.81.5-1.00.9-1.50.8-1.31.5-1.2
Light reinforcement 10.30.82.0-0.9-1.01.2-0.5-1.40.51.3-1.3-1.2-0.91.2-0.7-0.2-1.3-1.10.3-0.70.8-0.60.4-0.7-0.1-0.5
Light reinforcement 20.30.52.3-0.7-0.91.5-0.2-1.00.50.9-1.0-1.0-0.70.7-0.6-0.7-0.8-1.00.5-0.30.6-0.20.3-0.7-0.3-0.4
Bone: marrow area1.22.75.71.41.2-2.42.10.7-2.1-1.31.50.52.0-2.20.6-0.31.52.31.31.7-1.91.5-1.92.10.91.5
Bone: maximum diameter0.20.41.20.91.0-0.90.71.0-0.5-0.70.71.10.5-0.60.9-0.30.50.40.7-0.0-0.2-0.40.10.1-0.5-0.2
Bone: maximum force0.61.14.01.51.7-1.40.92.0-0.5-1.31.22.00.8-0.81.50.01.20.60.90.0-0.3-0.50.40.00.1-0.3
Bone: maximum moment0.71.24.21.61.7-1.21.02.0-0.5-1.21.12.10.7-0.61.7-0.21.00.41.1-0.1-0.1-0.60.5-0.20.3-0.6
Mean time between licks in bursts1.43.410.81.01.30.8-0.51.61.00.3-0.62.2-1.31.42.5-1.0-1.6-2.10.3-1.92.3-2.83.1-3.30.4-3.2
Mean num. licks in bursts0.40.71.70.30.1-0.90.9-0.3-1.1-0.30.5-0.51.0-0.8-0.30.00.51.00.41.3-1.11.3-1.31.20.41.0
Cd content in liver0.30.31.20.70.8-0.80.21.00.0-0.40.31.1-0.00.20.9-0.5-0.00.10.2-0.40.4-0.70.8-0.6-0.2-0.8
Co content in liver1.72.05.50.10.30.7-0.80.61.20.8-1.01.0-1.41.51.30.0-1.5-1.70.1-2.12.0-2.12.4-2.3-0.2-2.3
Cu content in liver0.20.20.8-0.00.00.2-0.30.10.30.2-0.30.2-0.40.50.5-0.8-0.6-0.5-0.3-0.40.6-0.30.7-0.9-0.7-0.7
Fe content in liver2.42.911.12.42.1-1.82.71.5-2.2-1.11.31.71.7-1.52.1-1.00.71.02.90.5-0.9-0.4-0.50.13.3-0.4
K content in liver0.90.82.6-1.3-1.21.3-1.1-1.00.50.1-0.2-1.3-0.20.2-1.6-0.40.2-0.4-1.50.8-0.41.4-0.70.5-0.70.9
Mg content in liver0.20.21.10.30.40.10.00.6-0.3-0.70.60.50.4-0.60.3-1.00.50.1-0.60.6-0.40.4-0.20.1-0.60.2
Mn content in liver1.31.53.9-1.6-1.51.2-1.7-1.31.41.3-1.2-1.2-1.30.9-1.22.0-1.1-0.7-1.9-0.60.8-0.30.40.0-1.40.2
Na content in liver0.30.31.3-0.1-0.30.20.5-0.9-0.70.4-0.4-0.90.20.4-0.0-0.6-0.7-0.51.10.3-0.10.3-0.4-0.31.2-0.2
Rb content in liver1.01.23.71.21.3-1.10.81.6-1.0-1.61.41.41.1-1.01.0-1.91.20.60.61.0-0.90.7-0.40.3-0.90.1
Se content in liver1.82.16.92.02.1-1.31.32.3-1.3-1.81.52.31.2-0.82.1-2.60.80.21.40.9-0.40.10.4-0.70.6-0.9
Sr content in liver1.31.11.8-1.3-1.20.9-1.4-1.21.31.3-1.3-1.0-1.31.3-0.91.3-1.2-0.9-1.0-0.91.0-0.50.7-0.7-0.8-0.4
Zn content in liver0.91.03.00.90.90.30.60.8-0.10.2-0.31.1-0.30.41.6-0.1-0.8-1.11.3-1.01.0-1.31.3-1.61.3-1.7
Bone: minimum diameter0.50.92.41.31.4-1.31.01.5-0.7-1.01.01.50.8-1.01.30.11.00.80.80.1-0.4-0.30.00.40.6-0.0
Time in familiar zone, hab. session 10.30.31.40.60.60.10.50.4-0.3-0.10.00.60.10.20.9-0.8-0.3-0.61.2-0.40.3-0.40.5-0.70.4-0.9
Time in novel zone, hab. session 10.70.71.8-0.1-0.1-0.90.1-0.1-0.6-0.50.7-0.40.7-0.9-0.50.40.71.3-1.01.2-1.01.1-1.21.30.21.3
Total zone transitions, hab. session 11.21.73.4-1.1-1.11.5-1.3-1.11.31.5-1.6-0.8-1.61.8-0.30.4-1.8-1.80.1-1.31.6-1.21.4-1.6-0.8-1.2
Total locomotion distance, hab. session 11.21.73.4-1.5-1.61.5-1.5-1.71.31.7-1.7-1.5-1.51.5-0.90.9-1.8-1.4-0.8-0.91.2-0.60.8-1.1-0.7-0.6
Locomotion velocity, hab. session 11.92.74.6-1.7-1.72.0-1.9-1.71.82.0-2.0-1.5-2.02.0-0.91.1-2.1-2.0-1.0-1.41.7-1.11.3-1.5-0.8-1.1
Time in familiar zone, hab. session 20.50.62.2-0.7-1.00.6-0.0-1.50.21.2-1.1-1.3-0.50.7-0.61.0-0.9-0.40.7-0.60.4-0.1-0.1-0.10.3-0.1
Time in novel zone, hab. session 20.91.01.91.01.1-1.20.81.3-0.9-1.41.41.11.1-1.20.5-1.01.21.1-0.21.0-1.00.6-0.60.70.10.6
Total zone transitions, hab. session 20.30.41.4-0.7-0.80.7-0.2-1.20.31.1-0.9-1.0-0.50.6-0.50.7-0.8-0.40.1-0.40.4-0.0-0.00.0-0.30.0
Total locomotion distance, hab. session 21.51.97.1-1.8-2.11.1-1.0-2.70.72.0-1.7-2.5-1.11.0-1.71.8-1.7-0.5-0.8-0.40.50.3-0.40.3-0.60.5
Locomotion velocity, hab. session 22.12.77.8-2.2-2.41.6-1.5-2.81.32.4-2.2-2.6-1.61.5-1.82.0-2.1-1.1-1.1-0.91.1-0.10.2-0.2-0.80.1
Novel to familiar place preference ratio0.10.10.80.00.2-0.2-0.20.50.2-0.40.40.40.1-0.2-0.00.50.60.3-0.90.4-0.20.6-0.00.5-0.30.3
Novelty place preference0.10.10.60.30.4-0.3-0.10.80.2-0.50.40.70.1-0.20.20.30.60.1-0.60.2-0.10.30.20.2-0.10.0
Time in novel zone, NPP test0.30.30.90.50.7-0.60.30.9-0.2-0.80.70.80.4-0.50.40.10.80.5-0.40.6-0.40.6-0.10.50.10.2
Total zone transitions, NPP test1.01.43.4-1.6-1.71.6-1.3-1.91.11.5-1.4-1.8-1.21.2-1.41.3-1.2-1.0-0.8-0.50.7-0.00.1-0.2-0.80.1
Total locomotion distance, NPP test2.73.710.0-2.7-2.92.1-2.0-3.21.62.4-2.2-3.1-1.71.5-2.62.6-1.8-1.0-1.7-0.70.80.1-0.20.2-1.10.7
Locomotion velocity, NPP test3.24.59.9-2.9-3.02.4-2.4-3.12.12.7-2.4-3.0-2.11.8-2.62.7-2.0-1.4-2.1-1.11.2-0.40.2-0.2-1.40.4
Intraocular pressure0.50.71.8-0.30.00.6-1.10.61.30.2-0.30.7-1.00.60.20.6-0.2-0.8-1.2-1.21.0-1.31.3-0.6-0.9-0.7
Delta distance traveled before/after self-admin2.52.65.3-1.2-1.01.6-1.9-0.62.21.4-1.6-0.3-2.02.1-0.51.2-1.5-1.9-0.9-2.32.0-2.22.0-1.90.2-1.5
Delta ambulatory time before/after self-admin1.72.14.5-1.1-0.81.4-1.9-0.32.11.1-1.3-0.1-1.81.8-0.51.4-1.1-1.7-1.3-2.11.8-1.91.9-1.6-0.2-1.2
Parametrial fat weight17.440.963.77.77.5-7.68.07.0-8.0-7.67.66.27.7-7.15.6-6.86.46.05.46.1-6.04.5-4.24.03.52.1
Pavlov. Cond. lever latency0.40.52.11.21.0-1.11.30.6-0.9-0.10.30.80.6-0.51.40.2-0.10.41.1-0.1-0.0-0.20.1-0.10.9-0.4
Pavlov. Cond. magazine entry latency1.11.42.81.11.2-1.21.11.3-1.3-1.71.61.01.4-1.30.6-1.61.41.10.71.4-1.31.2-0.90.90.60.7
Pavlov. Cond. change in total contacts0.30.32.2-0.4-0.10.3-0.90.50.3-0.80.60.30.0-0.0-0.5-0.70.5-0.0-1.50.6-0.30.60.00.1-0.30.3
Pavlov. Cond. index score0.20.21.10.20.30.1-0.10.6-0.2-0.90.70.40.4-0.4-0.1-1.00.80.1-0.20.6-0.50.5-0.30.20.00.3
Pavlov. Cond. latency score0.10.10.5-0.3-0.20.7-0.60.20.4-0.40.20.0-0.10.2-0.5-0.70.3-0.4-0.50.2-0.10.20.1-0.1-0.30.0
Pavlov. Cond. lever contacts0.20.20.8-0.5-0.40.1-0.5-0.10.1-0.40.3-0.40.1-0.2-0.9-0.60.50.3-0.60.6-0.50.5-0.50.5-0.40.7
Pavlov. Cond. magazine entry number1.41.83.7-1.1-1.31.4-1.0-1.51.31.9-1.8-1.2-1.61.5-0.51.6-1.8-1.4-0.2-1.61.5-1.31.1-1.2-0.2-1.0
Pavlov. Cond. intertrial magazine entries1.31.53.7-1.3-1.31.0-1.5-1.31.41.7-1.5-1.0-1.51.3-0.71.9-1.6-1.0-1.4-1.21.3-1.01.0-0.7-0.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.20.20.3-0.10.10.6-0.5-1.10.90.30.7-0.6-0.3-1.11.00.4-0.21.0-0.90.8-0.70.60.10.6
Pavlov. Cond. response bias1.01.22.61.01.1-1.00.81.3-1.1-1.61.51.01.3-1.20.4-1.51.41.00.21.3-1.21.0-0.80.80.40.7
Pavlov. Cond. lever latency1.92.66.1-1.7-1.52.5-2.1-1.12.31.5-1.7-0.9-2.02.1-1.10.7-1.3-2.1-1.2-1.81.7-1.21.6-1.4-0.8-1.1
Pavlov. Cond. magazine entry latency0.70.92.40.90.7-1.51.50.3-1.3-0.60.80.31.1-1.10.4-0.00.81.31.30.7-1.00.5-1.11.10.10.8
Pavlov. Cond. change in total contacts2.23.68.41.91.7-2.92.60.9-2.8-1.51.80.82.4-2.41.2-0.71.32.51.61.9-2.11.4-2.11.81.51.4
Pavlov. Cond. index score1.92.66.31.81.5-2.52.31.1-2.3-1.41.60.92.0-2.01.1-0.71.32.01.51.5-1.71.0-1.61.50.51.0
Pavlov. Cond. latency score1.41.84.61.51.3-2.21.90.9-1.9-1.21.40.81.7-1.71.0-0.61.11.71.31.3-1.40.8-1.31.20.40.8
Pavlov. Cond. lever contacts2.12.96.31.81.5-2.52.41.0-2.5-1.51.70.82.2-2.11.1-0.81.32.11.51.8-1.81.3-1.71.51.01.1
Pavlov. Cond. magazine entry number1.11.43.8-1.4-1.21.9-1.8-0.81.61.0-1.2-0.8-1.51.4-0.80.3-1.1-1.5-1.4-0.81.2-0.51.1-1.2-0.4-0.7
Pavlov. Cond. intertrial magazine entries0.20.41.7-0.9-0.81.1-1.0-0.50.80.4-0.4-0.6-0.60.3-0.80.6-0.2-0.4-1.3-0.20.3-0.00.1-0.1-0.40.2
Pavlov. Cond. lever-magazine prob. diff.2.43.16.82.01.8-2.62.51.3-2.5-1.71.91.12.3-2.21.3-1.01.52.11.81.7-1.91.1-1.71.50.81.0
Pavlov. Cond. response bias2.12.87.31.81.6-2.72.31.1-2.3-1.51.71.02.1-2.21.1-0.61.42.31.51.6-1.81.1-1.61.60.61.1
Time in closed arm before self-admin0.30.42.90.40.4-0.10.10.60.2-0.20.10.7-0.00.00.5-1.20.2-0.20.3-0.70.2-1.20.4-0.4-1.7-0.2
Time in closed arm after self-admin1.31.33.1-0.6-0.41.2-1.2-0.21.30.9-1.10.1-1.41.40.20.4-1.3-1.7-0.5-1.41.5-1.81.7-1.5-0.4-1.4
Time in open arm before self-admin0.40.45.50.0-0.20.00.6-0.8-0.60.5-0.4-0.70.10.1-0.11.0-0.60.20.60.3-0.10.7-0.4-0.02.3-0.1
Time in open arm after self-admin0.70.82.11.11.0-1.31.30.6-1.4-0.70.80.61.1-0.71.1-0.70.20.71.10.9-0.70.5-0.6-0.01.4-0.0
Bone: periosteal estimation0.91.83.81.81.7-2.01.91.5-1.5-1.31.41.51.5-1.61.4-0.31.31.41.60.7-1.00.3-0.70.91.00.3
Bone: periosteal perimeter0.10.21.20.60.5-0.90.60.2-0.30.20.00.40.2-0.40.71.1-0.10.50.6-0.60.1-0.70.10.20.2-0.1
Bone: post-yield work0.40.52.30.90.8-0.91.10.4-0.60.10.00.60.3-0.31.11.0-0.20.31.5-0.50.2-0.80.2-0.21.5-0.5
Progressive ratio test 1 active lever presses0.10.10.30.2-0.00.20.6-0.2-0.40.0-0.0-0.30.3-0.3-0.1-0.40.20.20.50.1-0.3-0.2-0.40.20.50.2
Progressive ratio test 1 breakpoint0.10.10.40.30.10.10.6-0.1-0.4-0.10.1-0.10.4-0.40.0-0.50.30.30.50.1-0.4-0.2-0.40.30.40.3
Progressive ratio test 1 inactive lever presses0.50.71.8-0.6-0.90.50.2-1.0-0.30.1-0.0-1.30.4-0.6-1.10.10.40.7-0.41.1-0.91.1-1.41.3-0.21.3
Progressive ratio test 2 active lever presses0.20.21.2-0.1-0.30.00.7-0.8-0.50.4-0.3-0.80.2-0.2-0.40.2-0.10.31.10.1-0.3-0.1-0.60.20.90.3
Progressive ratio test 2 breakpoint0.20.21.2-0.1-0.40.10.6-0.8-0.40.5-0.4-0.80.2-0.1-0.40.2-0.10.31.10.0-0.2-0.2-0.60.20.80.2
Progressive ratio test 2 inactive lever presses0.20.32.20.60.2-0.21.3-0.3-0.90.1-0.1-0.30.5-0.50.3-0.1-0.10.31.50.3-0.3-0.3-0.50.21.1-0.0
Incentive Sensitization - Responses0.30.42.2-0.2-0.40.10.3-0.9-0.30.8-0.7-0.8-0.20.3-0.10.7-1.0-0.31.0-0.10.3-0.60.0-0.61.5-0.4
Incentive Sensitization - Breakpoint0.30.42.1-0.2-0.50.10.3-1.1-0.30.9-0.8-0.9-0.20.3-0.10.7-1.0-0.21.0-0.10.3-0.5-0.1-0.51.4-0.4
Sum of active levers in priming session hrs 5-60.30.20.8-0.6-0.50.9-0.9-0.30.50.3-0.4-0.3-0.60.6-0.2-0.2-0.6-0.7-0.80.10.40.20.4-0.2-0.0-0.3
Progressive ratio1.82.76.1-0.9-0.92.1-1.4-0.81.51.6-1.9-0.4-1.91.90.31.1-2.5-2.30.0-1.62.2-1.92.2-2.20.2-2.2
Food seeking constrained by brief footshock3.03.76.9-2.5-2.52.0-2.2-2.62.22.5-2.4-2.5-2.22.1-2.32.2-1.8-1.4-1.6-1.61.5-0.50.7-0.8-0.6-0.2
Seeking ratio, punishment vs. effort0.60.92.9-0.2-0.3-1.00.5-0.5-0.5-0.20.5-0.80.8-0.8-1.10.01.21.3-0.40.6-1.21.3-1.61.5-0.01.7
Retroperitoneal fat weight21.591.6141.411.711.6-11.211.411.4-11.3-11.911.710.311.3-10.88.9-9.79.99.07.28.8-8.75.6-5.65.65.72.9
Reaction time number correct0.20.31.4-0.8-0.70.4-0.7-0.50.60.4-0.3-0.6-0.4-0.1-0.90.40.20.1-1.2-0.3-0.00.1-0.20.5-0.90.6
Reaction time mean minus median0.61.43.21.41.3-1.41.41.0-1.8-1.31.30.91.4-1.31.3-1.70.51.01.21.4-1.10.9-0.80.40.60.2
Reaction time mean minus median AUC0.41.14.71.21.2-0.91.11.1-1.4-1.21.11.01.1-0.81.4-2.20.40.41.21.1-0.70.7-0.3-0.00.3-0.2
Reaction time num false alarms2.63.67.8-1.0-1.01.6-1.5-0.92.32.1-2.2-0.3-2.32.2-0.22.3-2.0-2.2-0.1-2.72.5-2.82.4-2.0-0.9-2.0
Reaction time num false alarms AUC1.82.85.0-1.2-1.11.7-1.5-1.02.11.9-2.0-0.6-2.12.0-0.42.0-1.7-2.0-0.2-2.22.1-2.21.9-1.6-1.1-1.6
Reaction time trials correct on left0.20.31.4-0.8-0.70.4-0.7-0.50.60.4-0.3-0.6-0.4-0.1-0.90.40.20.1-1.2-0.3-0.00.1-0.20.5-0.90.6
Reaction time trials on left0.20.31.4-0.8-0.70.4-0.7-0.50.60.3-0.3-0.6-0.3-0.1-0.90.40.20.2-1.2-0.2-0.10.2-0.30.6-0.90.7
Reaction time mean1.82.85.81.61.3-1.92.10.9-2.4-1.71.80.72.2-2.10.9-1.31.41.81.62.1-2.01.8-1.81.50.71.1
Reaction time mean AUC1.52.45.01.61.4-1.82.01.0-2.2-1.61.70.82.0-1.91.0-1.31.31.61.61.9-1.71.5-1.51.20.70.9
Median of all reaction times1.72.44.71.41.1-1.72.00.8-2.2-1.51.60.52.0-1.90.5-1.01.51.81.41.9-1.91.8-1.81.50.61.2
Reaction time omissions0.40.72.00.60.6-1.20.60.5-1.1-1.00.90.41.0-0.80.5-1.40.40.80.41.3-0.81.0-0.70.50.20.4
Reaction time false alarm rate1.72.34.5-0.8-0.81.3-1.1-0.71.71.7-1.8-0.4-1.82.0-0.11.8-1.7-1.90.3-2.02.0-2.11.9-1.8-0.6-1.7
Reaction time premature initiation rate0.40.51.3-0.1-0.10.9-0.3-0.00.70.6-0.70.2-0.70.80.30.1-0.7-1.10.5-1.01.0-1.11.0-1.0-0.5-1.0
Reaction time premature initiations0.30.61.3-0.6-0.61.1-0.7-0.41.00.8-0.9-0.3-0.90.8-0.30.4-0.7-1.0-0.2-1.00.9-1.00.8-0.6-1.1-0.6
Std. dev. reaction times1.12.14.41.51.4-1.71.71.1-2.1-1.61.70.91.8-1.71.2-1.31.01.41.21.9-1.61.5-1.31.10.60.7
Reaction time trials completed0.20.31.4-0.8-0.70.4-0.7-0.50.60.3-0.3-0.6-0.3-0.1-0.90.40.20.2-1.2-0.2-0.10.2-0.30.6-0.90.7
Reaction time trials AUC0.20.31.2-0.7-0.70.3-0.5-0.50.50.3-0.2-0.6-0.2-0.2-0.90.50.30.3-1.1-0.1-0.20.2-0.40.7-0.90.8
Run reversals in cocaine runway, females0.90.92.51.41.2-1.31.60.9-1.3-0.80.80.91.1-0.91.1-0.50.70.81.10.6-0.70.4-0.50.51.10.0
Run reversals in cocaine runway, males1.21.23.00.40.4-1.40.70.5-0.8-1.01.10.21.1-1.3-0.31.01.61.6-0.10.9-1.41.1-1.41.7-0.71.6
Latency to leave start box in cocaine runway0.81.03.40.90.70.30.80.3-0.20.4-0.50.7-0.20.31.30.5-0.9-1.01.9-1.20.9-1.81.0-1.40.8-1.5
Latency to leave start box in cocaine runway, F1.21.44.61.71.6-0.51.41.4-0.6-0.30.31.70.3-0.32.00.1-0.2-0.52.1-0.90.6-1.71.1-1.20.9-1.6
Latency to leave start box in cocaine runway, M0.70.71.4-0.8-0.91.2-0.5-1.20.61.1-1.1-1.0-0.80.9-0.40.5-1.1-1.00.1-0.80.7-0.90.4-0.70.0-0.4
Std. dev. time between licks in bursts1.21.74.7-0.3-0.01.1-1.20.41.40.6-0.90.7-1.41.50.7-0.3-1.3-1.7-0.6-1.51.8-1.82.1-2.2-0.7-1.9
Total sessions with >9 infusions0.40.51.9-0.7-0.91.0-0.1-1.40.21.2-1.1-1.3-0.60.6-0.6-0.0-1.0-0.60.5-0.30.5-0.2-0.0-0.40.1-0.2
Short access day 1 total inactive lever presses0.20.21.00.30.20.40.50.10.10.4-0.40.2-0.30.30.20.3-0.3-0.61.0-0.60.5-0.60.5-0.51.0-0.8
Short access day 10 total inactive lever presses0.71.73.61.51.2-1.01.91.1-1.7-1.31.30.91.5-1.50.8-1.01.31.11.41.7-1.31.3-1.11.01.60.4
Short access day 1 total infusions1.82.44.3-1.5-1.61.9-1.2-1.91.42.1-2.1-1.6-1.71.8-1.01.2-2.0-1.90.1-1.61.6-1.51.1-1.50.6-1.1
Short access day 10 total infusions0.20.21.0-0.6-0.71.0-0.2-0.60.40.3-0.3-0.8-0.2-0.1-0.80.20.3-0.0-0.60.1-0.20.6-0.40.7-0.10.6
Short access total infusions0.30.41.2-0.2-0.30.80.1-0.60.20.8-0.8-0.4-0.50.50.00.1-0.8-0.80.7-0.70.7-0.90.5-0.71.1-0.7
Short access day 1 locomotion0.50.62.0-1.0-1.21.0-0.6-1.40.41.1-1.0-1.4-0.70.7-0.90.4-1.0-0.6-0.2-0.20.4-0.3-0.1-0.3-0.40.0
Short access day 10 total locomotion1.12.05.8-2.1-2.21.9-1.3-2.21.21.4-1.3-2.4-1.00.8-2.31.0-0.6-0.4-1.60.10.21.1-0.60.8-1.41.0
Short access total locomotion1.62.06.2-2.0-2.21.8-1.2-2.41.11.6-1.5-2.5-1.00.8-2.31.1-0.6-0.4-1.3-0.30.20.4-0.70.6-1.31.0
One hour access (0.3 mA shock)0.70.92.9-1.1-1.31.2-0.5-1.70.61.4-1.3-1.6-0.80.8-1.00.8-1.1-0.70.1-0.50.5-0.1-0.1-0.30.2-0.1
Compulsive drug intake0.81.02.0-1.2-1.11.0-1.4-1.01.21.1-1.1-0.9-1.21.1-0.61.0-1.1-1.0-1.3-0.71.0-0.00.7-0.70.1-0.4
One hour access (shock baseline)0.20.42.80.30.10.30.8-0.3-0.20.6-0.5-0.1-0.10.20.3-0.1-0.5-0.41.7-0.70.4-1.20.2-0.60.4-0.7
Social response proportion4.95.611.12.42.2-3.33.01.7-3.0-2.42.61.43.0-2.71.2-1.22.63.02.22.3-2.61.5-2.32.21.61.6
Social responses0.30.31.10.0-0.0-0.90.2-0.1-0.4-0.30.5-0.20.6-0.5-0.50.50.60.90.10.6-0.80.5-0.91.0-0.01.0
Social time0.71.02.00.80.6-1.21.40.3-1.3-0.80.90.11.2-1.00.1-0.31.11.21.41.1-1.21.3-1.21.20.50.9
Soleus weight0.10.20.70.70.7-0.80.60.7-0.4-0.50.40.70.4-0.30.7-0.20.30.30.70.0-0.1-0.30.1-0.10.5-0.3
Bone: stiffness0.30.52.40.91.1-1.00.21.40.1-0.60.61.50.1-0.31.10.20.50.3-0.0-0.50.3-0.80.8-0.2-0.8-0.5
Tibialis anterior weight1.13.86.92.42.3-2.62.52.0-2.5-2.12.21.82.3-2.21.9-1.91.61.91.81.7-1.71.1-1.20.91.80.5
Time to tail flick, vehicle, before self-admin4.14.39.63.13.0-2.22.63.0-2.2-2.42.23.02.0-1.83.1-2.41.40.92.51.0-1.0-0.2-0.00.11.3-0.7
Time to tail flick, vehicle, after self-admin0.30.41.20.91.0-0.60.61.1-0.6-0.90.81.00.6-0.81.0-0.10.50.30.30.6-0.40.3-0.00.2-0.4-0.1
Time to tail flick, test, before self-admin0.40.41.7-0.2-0.30.7-0.2-0.50.30.6-0.6-0.3-0.50.7-0.2-0.9-0.7-0.80.5-0.80.6-1.30.4-0.7-1.3-0.4
Time to tail flick, test, after self-admin0.30.31.5-0.1-0.21.2-0.1-0.10.50.4-0.5-0.0-0.50.6-0.10.3-0.2-0.90.5-0.40.6-0.60.6-0.2-0.7-0.6
Delta time to tail flick, vehicle, before/after SA1.21.12.9-1.5-1.41.4-1.5-1.21.21.0-1.0-1.2-1.10.8-1.41.1-0.7-0.7-1.7-0.30.60.30.3-0.2-1.10.2
Delta time to tail flick, test, before/after SA0.20.22.0-0.1-0.10.20.10.0-0.0-0.20.2-0.10.2-0.4-0.21.40.50.2-0.20.6-0.31.0-0.40.90.30.4
Tibia length3.28.825.94.54.7-3.63.34.8-2.3-3.02.85.12.2-2.14.8-2.51.91.33.30.3-0.5-1.51.1-0.81.7-1.8
Ambulatory time before self-admin0.91.44.20.40.3-1.10.80.1-1.5-1.01.2-0.21.4-1.3-0.0-0.70.81.4-0.02.0-1.62.1-1.61.5-0.01.4
Ambulatory time after self-admin0.40.52.0-1.0-0.70.6-1.4-0.41.10.4-0.5-0.4-0.80.8-0.71.0-0.4-0.5-1.4-0.80.5-0.20.5-0.2-0.30.0
Bone: tissue strength0.20.20.90.60.6-1.00.60.4-0.5-0.20.40.60.4-0.50.6-0.00.20.60.2-0.1-0.2-0.3-0.20.20.80.2
Total heroin consumption0.20.33.30.1-0.00.30.4-0.2-0.6-0.10.1-0.20.3-0.20.3-1.8-0.2-0.10.40.5-0.30.6-0.40.30.70.1
Bone: trabecular number0.81.34.00.30.40.6-0.20.40.70.7-0.80.8-1.01.21.2-0.4-1.2-1.50.8-1.31.5-1.71.8-2.0-0.5-2.0
Bone: trabecular spacing1.41.94.10.80.8-1.30.81.1-1.1-1.71.80.71.5-1.8-0.2-0.42.01.9-0.61.6-1.81.5-1.62.00.21.7
Bone: trabecular thickness1.31.65.00.80.80.50.40.70.10.1-0.41.1-0.51.11.6-1.7-1.0-1.62.2-1.11.2-1.61.6-2.20.1-2.2
Bone: trabecular tissue density0.20.32.20.70.7-0.40.70.6-0.6-0.60.60.60.6-0.50.6-0.50.50.40.70.3-0.4-0.1-0.20.01.50.0
Water consumed over 24 hours0.10.10.3-0.1-0.20.10.0-0.30.20.4-0.3-0.2-0.20.2-0.10.5-0.2-0.20.3-0.50.2-0.40.10.1-0.40.0
Number of responses in last shaping day1.31.42.6-1.3-1.41.3-1.1-1.51.21.6-1.6-1.3-1.41.4-0.80.8-1.4-1.2-0.3-1.31.2-1.20.8-0.8-0.8-0.6