Hub : Genes

Kif16b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA XM_039105041.1 0.03 0.02 1.2e-03 0.02 0.03 0.03 0.03 1.2e-03 3.3e-04 6.4e-04 3.4e-04
2 NAcc isoform ratio XM_006235108.4 0.03 0.02 4.1e-03 0.01 0.02 0.01 0.02 1.4e-02 1.9e-03 2.2e-02 4.3e-03
3 NAcc alternative polyA XM_039105041.1 0.06 0.04 4.7e-06 0.02 0.04 0.04 0.03 1.3e-03 5.5e-06 2.4e-05 8.9e-05
4 Adipose isoform ratio XM_006235108.4 0.07 0.04 2.9e-06 0.02 0.03 0.03 0.02 5.5e-03 1.7e-04 7.7e-04 3.1e-03
5 Liver gene expression Kif16b 0.24 0.09 0.0e+00 0.19 0.19 0.2 0.19 1.3e-20 7.5e-21 1.4e-21 5.0e-21
6 Liver alternative polyA XM_039105041.1 0.16 0.08 0.0e+00 0.12 0.13 0.12 0.12 5.0e-13 6.2e-14 3.4e-13 1.7e-13
7 Liver isoform ratio NM_001107783.2 0.04 0.02 1.3e-04 0.03 0.02 0.01 0.02 2.2e-04 1.9e-03 2.1e-02 2.1e-03
8 Liver alternative polyA XM_039105043.1 0.11 0.07 6.4e-09 0.04 0.06 0.05 0.05 1.8e-05 4.2e-07 6.3e-06 1.4e-06
9 NAcc gene expression Kif16b 0.08 0.05 2.1e-06 0.04 0.04 0.02 0.03 2.8e-05 3.3e-05 1.4e-03 3.2e-04
10 BLA gene expression Kif16b 0.05 0.04 2.2e-03 0.02 0.02 0.01 0.01 3.2e-02 1.9e-02 7.9e-02 8.2e-02
11 Liver isoform ratio XM_039105043.1 0.03 0.02 1.8e-03 -0 0.01 0.01 0 3.9e-01 1.6e-02 6.4e-02 3.6e-01
12 Adipose alternative polyA XM_039105041.1 0.07 0.04 1.6e-06 0.03 0.03 0.03 0.03 4.0e-04 4.8e-04 5.2e-04 8.3e-04
13 Brain gene expression Kif16b 0.15 0.08 1.4e-08 0.08 0.1 0.1 0.1 8.8e-08 8.6e-10 7.0e-10 2.8e-09
14 PL gene expression Kif16b 0.03 0.02 6.1e-03 0 0.01 0.01 0 1.9e-01 5.8e-02 5.1e-02 2.0e-01
15 Liver intron excision ratio chr3_130221648_130253917 0.05 0.03 1.4e-04 0.01 0.03 0.03 0.02 1.9e-02 7.5e-04 6.1e-04 1.3e-03
16 Liver intron excision ratio chr3_130035698_130048812 0.03 0.02 2.0e-03 0.02 0.01 0 0.01 5.6e-03 6.7e-03 8.7e-02 1.7e-02
17 Liver intron excision ratio chr3_130047556_130048812 0.03 0.02 2.3e-03 0.02 0.01 0 0.01 4.6e-03 1.0e-02 1.2e-01 3.0e-02
18 Adipose gene expression Kif16b 0.8 0.06 0.0e+00 0.56 0.58 0.58 0.58 4.1e-75 2.2e-79 8.2e-80 2.7e-78
19 Adipose mRNA stability Kif16b 0.5 0.12 0.0e+00 0.29 0.29 0.29 0.28 2.1e-32 1.5e-32 6.6e-33 1.3e-31
20 Liver mRNA stability Kif16b 0.13 0.07 1.4e-06 0.01 0.03 0.03 0.03 7.8e-03 1.0e-04 3.5e-04 9.9e-05
21 Liver isoform ratio XM_006235108.4 0.03 0.02 2.2e-04 0.03 0.03 0.04 0.03 2.2e-04 6.6e-04 4.8e-05 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.81.33.50.30.50.40.6-0.8-0.6-0.70.7-1.4-0.90.9-1.3-0.8-1.61.6-1.81.81.91.8-0.11.3
Area under the delay curve0.30.31.4-0.4-0.5-0.4-0.70.00.10.6-0.20.3-0.0-0.11.20.20.9-0.50.4-0.4-0.5-0.3-0.3-0.8
BMI with tail8.628.046.96.96.56.56.26.76.66.3-6.1-5.86.4-6.3-5.2-5.8-3.7-4.92.9-2.9-2.6-2.7-1.0-2.1
BMI without tail7.515.429.04.54.24.33.95.44.94.8-4.6-3.44.9-4.9-2.7-3.6-1.6-4.73.5-3.5-3.2-3.30.1-2.2
Body weight10.644.583.09.09.19.19.17.97.77.8-6.8-7.77.7-7.2-7.8-7.2-6.6-4.82.0-2.0-1.4-2.1-2.6-1.5
Weight adjusted by age0.60.71.81.01.21.21.30.90.70.9-0.5-0.61.0-0.7-1.0-0.3-1.2-0.50.0-0.0-0.0-0.3-1.0-0.5
Bone surface0.20.31.10.50.50.40.40.10.3-0.0-0.4-0.8-0.1-0.1-0.9-1.0-0.30.4-0.60.60.60.6-0.10.6
Bone volume0.40.71.60.50.60.50.7-0.2-0.2-0.40.2-1.3-0.50.5-1.3-0.9-1.10.9-1.21.21.21.10.41.1
Breakpoint value in progressive ratio session0.30.31.70.40.30.20.20.71.00.5-1.3-0.10.6-0.9-0.4-0.80.7-0.60.4-0.4-0.4-0.40.30.1
Number of licking bursts0.50.61.70.30.40.40.6-0.4-0.3-0.30.6-1.0-0.30.5-0.7-0.3-1.30.8-1.21.21.21.2-1.10.4
Context. condit. distance diff. score0.30.31.5-0.7-0.6-0.5-0.5-0.6-0.7-0.50.90.8-0.40.60.81.2-0.00.20.1-0.1-0.1-0.10.3-0.3
Locomotion velocity, session 11.92.05.0-1.9-2.1-2.1-2.2-1.3-1.5-1.61.41.5-1.51.32.01.41.80.30.2-0.2-0.6-0.2-0.2-0.4
Locomotion distance, session 14.15.29.5-3.0-3.1-3.1-3.0-3.0-2.8-2.82.62.2-2.82.72.42.21.82.0-1.11.10.81.1-0.20.6
Locomotion velocity, session 22.32.75.5-2.2-2.3-2.3-2.3-1.8-1.8-1.91.62.1-1.91.72.11.81.81.0-0.30.30.10.3-0.10.3
Locomotion distance, session 25.17.215.3-3.7-3.8-3.9-3.9-2.9-3.0-3.12.53.0-3.12.83.32.73.21.6-0.40.40.00.41.30.7
Locomotion velocity, session 32.93.48.2-2.3-2.2-2.1-2.1-2.4-2.6-2.42.91.1-2.12.42.02.40.31.5-0.80.80.60.8-0.10.0
Locomotion distance, session 31.11.23.0-1.3-1.2-1.1-1.1-1.5-1.5-1.11.70.7-1.21.51.11.40.01.0-0.60.60.50.6-0.40.1
Stereotopy head waving bouts, day 30.70.82.50.81.00.81.10.20.3-0.1-0.3-1.10.0-0.0-1.6-1.0-1.00.8-1.11.11.31.10.61.3
Stereotopy head waving duration, day 30.20.21.20.40.50.40.60.40.30.0-0.4-0.30.2-0.2-0.7-0.4-0.3-0.0-0.20.20.30.21.10.6
Locomotion velocity, session 71.41.53.5-1.4-1.1-1.1-0.9-1.4-1.8-1.51.90.9-1.51.70.71.70.01.2-0.90.90.80.71.40.8
Locomotion distance, session 70.91.13.6-1.1-1.0-0.9-0.9-1.0-1.7-1.11.90.4-1.21.51.01.5-0.30.7-0.30.30.20.31.80.3
Stereotopy head waving bouts, day 70.40.51.00.50.50.50.50.90.60.6-0.5-0.40.9-0.80.0-0.0-0.2-1.01.0-1.0-0.9-1.00.9-0.6
Stereotopy head waving duration, day 70.10.10.70.30.30.20.30.00.10.0-0.1-0.80.0-0.0-0.3-0.4-0.30.2-0.20.20.30.40.30.1
Locomotion velocity, session 81.51.83.7-1.8-1.9-1.9-1.9-1.4-1.4-1.71.11.9-1.41.21.71.61.70.6-0.10.1-0.1-0.00.6-0.0
Locomotion distance, session 84.46.412.3-3.4-3.4-3.3-3.3-2.8-3.2-2.93.13.0-2.72.83.33.51.91.4-0.20.2-0.10.11.1-0.0
Degree of sensitization distance0.30.34.20.40.40.30.40.70.20.2-0.3-0.40.2-0.2-0.4-0.3-0.1-0.40.2-0.2-0.2-0.32.00.3
Degree of sensitization stereotypy0.50.61.30.50.50.50.40.90.70.8-0.6-0.31.0-0.90.20.0-0.1-1.11.1-1.1-1.1-1.10.1-1.0
Conditioned locomotion0.81.03.30.40.70.60.9-0.1-0.6-0.10.7-1.3-0.50.7-1.2-0.3-1.50.9-1.31.31.21.21.81.3
Cocaine response after cond. corrected1.41.63.3-1.4-1.2-1.3-1.1-1.4-1.8-1.61.80.8-1.61.70.81.50.11.2-0.70.70.70.71.60.9
Cocaine response after cond. not corrected2.22.44.5-1.4-1.1-1.2-1.0-1.7-2.0-2.02.00.5-2.02.10.31.2-0.22.0-1.41.41.51.51.91.7
Cocaine response before conditioning0.40.41.50.30.30.20.3-0.3-0.1-0.5-0.1-0.6-0.50.3-0.9-0.7-0.20.9-0.90.91.11.20.41.2
Saline control response0.20.31.80.50.50.30.40.70.60.2-0.9-0.10.2-0.5-0.7-0.60.5-0.30.4-0.4-0.2-0.41.40.8
Bone: connectivity density1.21.85.0-0.3-0.2-0.3-0.1-1.5-0.9-1.10.8-0.9-1.41.3-0.9-0.7-0.82.1-2.22.22.22.2-0.81.5
Bone: cortical apparent density0.10.10.60.10.10.20.2-0.2-0.20.00.4-0.10.00.2-0.10.1-0.80.3-0.10.10.40.3-0.8-0.0
Bone: cortical area1.42.08.31.82.02.02.20.70.70.8-0.2-2.40.8-0.4-2.1-1.4-2.90.4-0.60.61.10.9-0.80.5
Bone: cortical porosity0.91.03.61.31.31.31.20.61.01.1-0.9-1.90.6-0.7-1.3-1.5-1.20.0-0.60.60.60.8-0.30.2
Bone: cortical porosity1.31.55.01.71.61.71.60.91.11.3-0.9-2.20.9-0.9-1.6-1.6-1.7-0.2-0.30.30.50.5-0.30.1
Bone: cortical thickness2.54.116.02.22.42.52.70.30.50.90.1-3.40.6-0.1-2.8-1.9-4.01.2-1.61.62.22.0-1.81.0
Bone: cortical thickness1.61.87.80.20.40.60.7-1.1-0.7-0.31.2-1.4-0.50.9-0.7-0.2-2.21.6-1.91.92.01.9-2.80.4
Bone: cortical tissue density0.00.10.5-0.00.00.10.1-0.2-0.2-0.00.40.00.00.2-0.00.2-0.60.20.0-0.00.30.2-0.7-0.1
Condit. Reinf. active minus inactive responses0.50.51.70.81.00.91.10.30.40.4-0.4-0.70.2-0.2-1.3-0.5-0.80.5-0.70.70.90.70.71.0
Condit. Reinf. active-inactive response ratio0.30.41.10.60.80.80.90.40.30.3-0.2-0.50.2-0.1-1.0-0.2-0.80.3-0.50.50.70.50.90.8
Condit. Reinf. active responses0.10.10.20.10.30.20.40.10.10.2-0.20.40.1-0.1-0.40.3-0.00.2-0.20.20.30.20.40.5
Condit. Reinf. inactive responses0.40.41.6-0.6-0.6-0.6-0.70.00.0-0.1-0.11.20.1-0.20.90.71.3-0.60.8-0.8-0.8-0.80.1-0.6
Incentive salience index mean0.10.10.5-0.10.1-0.00.2-0.2-0.1-0.1-0.10.4-0.20.1-0.40.20.10.6-0.50.50.70.60.20.7
Condit. Reinf. lever presses0.30.41.8-0.5-0.5-0.5-0.5-0.10.20.2-0.31.30.3-0.30.70.71.1-0.40.7-0.7-0.6-0.6-0.7-0.7
Condit. Reinf. active minus inactive responses0.70.910.90.40.40.30.31.20.40.2-0.60.00.4-0.5-0.3-0.00.6-1.00.9-0.9-0.9-0.93.30.4
Condit. Reinf. active-inactive response ratio0.60.63.50.30.20.20.11.10.60.4-0.80.10.5-0.70.0-0.20.7-1.11.1-1.1-1.2-1.11.9-0.1
Condit. Reinf. active responses0.81.17.70.30.30.20.11.30.60.4-0.80.60.7-0.80.20.30.9-1.41.4-1.4-1.4-1.32.8-0.1
Condit. Reinf. inactive responses0.10.20.40.40.50.40.50.50.60.5-0.70.40.6-0.6-0.30.00.2-0.40.4-0.4-0.1-0.30.4-0.0
Condit. Reinf. lever presses1.82.55.50.70.30.2-0.01.91.81.2-2.20.51.5-1.90.3-0.71.9-2.42.2-2.2-2.2-2.11.6-1.0
Condit. Reinf. lever reinforcers received1.01.49.00.30.20.10.01.40.80.5-1.10.70.7-1.00.20.11.3-1.61.6-1.6-1.5-1.53.0-0.1
Conditioned reinforcement - actives2.02.04.9-1.7-2.0-2.1-2.2-1.7-1.2-2.20.71.0-1.91.31.60.22.21.1-0.50.50.50.80.30.7
Conditioned reinforcement - inactives1.41.54.9-1.3-1.4-1.5-1.3-1.7-1.4-2.21.20.7-1.61.50.80.60.71.5-1.01.01.01.0-0.10.8
Conditioned locomotion2.32.85.0-2.1-2.2-2.2-2.2-2.1-1.9-2.11.51.6-2.21.91.71.01.71.5-1.01.00.91.10.30.9
Patch foraging indifference point 0 sec0.20.31.0-0.7-0.6-0.7-0.5-0.7-0.6-0.90.51.0-0.60.60.10.90.50.6-0.30.30.30.10.20.4
Patch foraging indifference point AUC1.51.86.7-1.8-1.7-1.7-1.6-1.4-1.3-1.21.12.6-1.21.21.31.91.50.8-0.40.40.30.2-1.10.2
Delay disc. indifference point, 0s delay0.50.61.60.40.30.30.00.90.91.3-1.1-0.20.7-0.90.4-0.50.9-1.10.7-0.7-0.9-0.7-0.7-0.9
Delay disc. indifference point, 16s delay0.60.61.3-1.1-1.1-1.0-1.1-0.9-0.8-0.50.61.0-1.00.81.00.70.90.6-0.50.50.50.6-0.10.2
Delay disc. indifference point, 2s delay1.11.23.00.30.00.2-0.31.11.11.5-1.30.10.9-1.20.7-0.51.4-1.71.5-1.5-1.6-1.40.4-1.3
Delay disc. indifference point, 24s delay1.00.93.0-1.1-1.0-0.8-1.0-1.2-1.4-0.71.7-0.0-1.11.41.40.9-0.50.8-0.40.40.30.6-1.0-0.2
Delay disc. indifference point, 4s delay0.80.82.30.60.60.80.51.10.81.3-0.60.01.1-1.00.30.2-0.2-1.41.1-1.1-1.2-1.2-0.7-1.5
Delay disc. indifference point, 8s delay0.60.63.7-1.0-1.1-1.0-1.3-0.4-0.6-0.00.60.4-0.50.51.90.61.0-0.40.6-0.6-0.6-0.2-0.2-0.9
Indifference point function ln k0.30.53.00.90.80.70.80.40.50.0-0.4-1.70.4-0.4-0.7-1.2-1.0-0.2-0.10.10.10.20.3-0.1
Indifference point function log k0.30.53.00.90.80.70.80.40.50.0-0.4-1.70.4-0.4-0.7-1.2-1.0-0.2-0.10.10.10.20.3-0.1
Patch foraging total patch changes 0 sec0.50.82.3-1.2-1.1-1.2-0.9-1.0-0.9-1.20.81.5-0.80.90.61.41.00.7-0.30.30.20.00.20.4
Patch foraging total patch changes 12 sec0.20.21.3-0.2-0.1-0.1-0.10.30.20.4-0.21.20.4-0.30.20.70.5-0.40.5-0.5-0.5-0.7-0.1-0.3
Patch foraging total patch changes 18 sec2.02.610.3-2.2-1.9-2.0-1.8-1.4-1.7-1.61.43.2-1.41.41.62.81.90.80.1-0.1-0.1-0.21.10.4
Patch foraging total patch changes 24 sec0.91.26.2-1.4-1.2-1.3-1.2-0.7-0.9-0.60.62.5-0.70.71.11.91.70.30.2-0.2-0.3-0.30.60.1
Patch foraging total patch changes 6 sec0.30.53.0-0.9-0.6-0.7-0.4-0.5-0.5-0.60.51.7-0.30.50.31.50.70.50.1-0.10.0-0.3-0.20.4
Patch foraging time to switch 0 sec1.82.85.22.22.32.22.22.01.92.1-1.8-2.11.8-1.8-1.9-1.9-1.4-1.10.5-0.5-0.2-0.41.20.0
Patch foraging water rate 0 sec2.23.57.7-2.6-2.5-2.4-2.5-2.0-2.1-1.92.22.8-1.61.82.62.81.50.60.1-0.1-0.3-0.2-1.3-0.6
Patch foraging water rate 12 sec2.03.06.8-2.3-2.2-2.0-2.1-2.1-2.4-2.12.61.5-1.92.22.22.40.51.3-0.30.30.30.60.3-0.1
Patch foraging water rate 18 sec3.75.013.7-2.5-2.3-2.2-2.0-3.0-3.3-3.03.71.2-2.63.11.92.8-0.52.3-1.31.31.21.30.20.3
Patch foraging water rate 24 sec2.53.411.2-2.3-2.1-1.9-1.9-2.1-2.8-2.43.31.3-1.92.52.22.7-0.41.1-0.20.20.00.2-0.6-0.4
Patch foraging water rate 6 sec1.52.35.3-1.3-1.0-0.9-0.7-2.0-2.1-1.52.30.7-1.82.10.51.7-0.72.0-1.71.71.71.60.11.1
Seeking ratio, delayed vs. immediate footshock0.30.41.20.90.80.70.70.50.70.5-0.7-1.00.5-0.6-0.8-1.1-0.7-0.30.0-0.00.00.1-0.20.2
Distance traveled before self-admin1.11.22.60.0-0.1-0.2-0.31.11.10.9-1.41.21.0-1.30.7-0.21.4-1.61.5-1.5-1.5-1.6-0.3-0.8
Distance traveled after self-admin0.20.31.4-0.7-0.5-0.4-0.4-0.5-0.50.10.61.2-0.30.50.60.90.10.3-0.20.20.1-0.0-0.7-0.1
Extensor digitorum longus weight0.31.22.11.10.90.90.71.41.41.3-1.4-0.61.4-1.5-0.4-1.0-0.0-1.51.0-1.0-1.1-1.1-1.3-1.1
Bone: elastic displacement0.30.31.10.70.70.70.70.20.40.5-0.2-0.90.3-0.3-0.7-0.6-0.90.1-0.30.30.30.3-1.00.1
Bone: elastic work2.43.05.32.32.22.32.21.82.12.2-1.9-2.12.0-2.0-1.9-2.1-1.5-1.10.6-0.6-0.4-0.4-1.6-0.5
Bone: endosteal estimation1.22.75.71.51.31.21.02.42.01.6-2.3-0.71.8-2.1-0.7-1.40.6-2.31.8-1.8-1.9-1.91.0-0.8
Bone: endosteal perimeter0.30.63.10.30.20.10.01.10.60.3-0.90.20.5-0.7-0.0-0.40.9-1.11.0-1.0-1.1-1.11.8-0.1
Epididymis fat weight8.219.134.15.85.85.85.75.15.35.1-4.8-5.05.1-4.9-4.9-5.0-3.8-3.21.6-1.6-1.0-1.4-2.5-1.1
Delta time in closed arm before/after self-admin0.50.51.7-0.9-0.7-0.8-0.6-0.8-0.7-1.00.61.3-0.50.60.61.30.50.6-0.30.30.40.20.20.4
Delta time in open arm before/after self-admin1.51.53.61.71.81.81.81.21.01.3-0.7-1.91.1-0.9-1.6-1.2-1.8-0.4-0.10.10.20.1-0.2-0.0
Diff in mean of infusions in LGA sessions0.60.61.7-0.6-0.7-0.7-0.80.20.20.1-0.41.10.2-0.41.00.71.3-0.91.2-1.2-1.1-1.10.4-0.6
Delay discount exponential model param0.20.21.40.50.60.40.70.10.1-0.4-0.1-0.30.2-0.1-1.2-0.3-0.70.3-0.30.30.30.10.50.7
Extinction: sum of active levers before priming0.10.10.40.10.0-0.1-0.10.20.40.1-0.60.00.2-0.4-0.1-0.30.6-0.30.3-0.3-0.3-0.3-0.00.0
Active lever presses in extinction session 60.50.51.71.00.90.80.80.60.80.3-0.8-1.30.5-0.6-1.0-1.3-0.6-0.2-0.10.10.00.1-0.1-0.0
Bone: final force1.11.86.81.81.92.02.11.30.91.3-0.4-1.91.3-0.9-1.5-1.1-2.6-0.60.2-0.2-0.0-0.2-1.2-0.4
Bone: final moment1.11.86.91.71.92.02.01.10.91.2-0.3-2.01.2-0.8-1.6-1.2-2.6-0.40.0-0.00.20.0-1.3-0.2
Food consumed during 24 hour testing period1.21.45.61.31.31.31.40.10.40.3-0.2-2.40.1-0.0-1.8-1.6-1.90.8-1.31.31.31.3-0.30.8
Glucose1.42.23.61.91.91.81.81.91.81.7-1.8-1.11.7-1.8-1.6-1.6-0.8-1.20.8-0.8-0.7-0.9-1.0-0.2
Heart weight1.72.45.51.91.91.81.81.91.72.1-1.7-2.41.6-1.6-1.6-2.0-1.1-1.20.9-0.9-0.5-0.70.9-0.1
Delay discount hyperbolic model param0.30.31.10.30.40.20.6-0.2-0.1-0.70.1-0.3-0.10.2-1.1-0.2-0.70.7-0.60.60.60.40.41.0
Intermittent access intake day 1-15 change0.80.84.0-0.2-0.7-0.8-1.00.30.7-0.0-1.20.10.1-0.70.7-0.92.0-0.91.2-1.2-1.1-0.70.3-0.5
Intermittent access intake escalation0.70.73.7-0.2-0.7-0.8-1.00.20.60.0-1.10.10.1-0.60.7-0.91.9-0.81.1-1.1-1.1-0.70.3-0.5
Intermittent access intake escalation 21.71.74.00.90.30.2-0.11.21.70.9-2.0-0.91.1-1.70.1-2.01.2-1.71.8-1.8-1.6-1.20.1-1.0
Intermitt. access day 1 inactive lever presses0.50.62.00.80.80.50.90.41.00.4-1.4-0.00.5-0.8-1.2-0.90.30.4-0.60.60.70.50.11.1
Intermitt. access day 15 inactive lever presses0.80.92.41.41.31.11.30.81.20.1-1.3-1.30.8-1.0-1.5-1.4-0.8-0.0-0.10.10.30.30.20.4
Intermitt. access escalation Index1.21.13.51.41.61.51.70.70.80.5-0.6-1.20.7-0.6-1.9-0.9-1.50.3-0.80.80.90.7-0.10.6
Intermittent access day 1 total infusions0.40.42.20.60.70.70.7-0.0-0.2-0.10.4-1.0-0.10.3-0.7-0.4-1.50.5-0.70.70.80.7-0.20.4
Intermittent access day 15 total infusions0.10.10.90.30.10.0-0.1-0.10.2-0.3-0.3-0.7-0.2-0.0-0.2-1.00.00.2-0.20.20.40.50.10.3
Intermittent access terminal intake (last 3 days)0.20.31.60.70.50.40.40.30.50.1-0.7-0.90.1-0.4-0.5-1.2-0.20.1-0.20.20.40.50.00.4
Intermittent access total infusions0.30.31.10.60.50.50.5-0.00.1-0.1-0.1-1.1-0.10.0-0.6-1.0-0.70.5-0.70.70.70.8-0.10.6
Intermittent access day 1 locomotion0.10.10.3-0.1-0.2-0.2-0.3-0.4-0.4-0.50.4-0.3-0.60.50.2-0.3-0.20.4-0.40.40.40.60.00.3
Intermittent access day 15 total locomotion1.01.03.10.10.0-0.10.0-0.8-0.4-1.00.2-0.8-1.00.7-0.7-1.1-0.31.5-1.61.61.81.80.21.5
Intermittent access total locomotion0.80.91.7-0.8-0.8-0.9-0.9-1.2-1.0-1.20.90.1-1.31.20.50.00.21.2-1.01.01.11.20.11.0
Intermittent access standard deviation0.70.74.5-0.8-1.1-1.2-1.4-0.20.2-0.3-0.70.8-0.3-0.21.0-0.22.1-0.50.8-0.8-0.9-0.60.4-0.3
Left kidney weight1.64.48.02.82.82.82.72.62.32.6-2.1-2.82.3-2.2-2.3-2.3-1.9-1.70.9-0.9-0.6-0.8-0.1-0.3
Right kidney weight1.43.98.72.62.82.82.82.11.92.5-1.7-3.01.9-1.7-2.6-2.3-2.3-0.80.0-0.00.2-0.1-0.10.4
Cocaine induced anxiety1.31.53.6-1.2-1.4-1.2-1.6-0.2-0.6-0.40.61.4-0.20.21.91.41.3-1.11.7-1.7-1.7-1.40.1-1.5
Post-drug Anxiety2.12.47.00.50.40.60.21.51.00.9-0.60.61.7-1.40.70.8-0.0-2.52.7-2.7-2.6-2.5-0.5-2.4
Baseline Anxiety3.63.89.42.82.92.93.12.12.22.0-2.0-1.82.4-2.1-2.5-1.7-2.3-1.00.2-0.2-0.0-0.5-0.7-0.2
Tail length0.61.95.31.82.22.12.31.31.11.4-0.7-1.71.2-0.9-2.0-1.1-2.1-0.3-0.40.40.60.1-0.80.6
Length with tail2.48.722.44.04.54.44.72.72.73.0-2.2-3.62.8-2.3-4.3-3.0-4.2-0.5-0.90.91.20.5-1.80.7
Length without tail2.55.412.83.13.33.23.51.62.11.9-1.8-2.91.8-1.6-3.6-2.8-3.30.2-1.11.11.41.0-1.90.7
Times rat made contact with spout0.70.82.60.70.50.40.31.11.31.0-1.60.01.0-1.3-0.2-1.01.0-1.10.9-0.9-1.0-1.0-0.5-0.4
Lifetime Intake0.30.30.8-0.1-0.1-0.2-0.1-0.5-0.4-0.70.3-0.4-0.60.5-0.2-0.4-0.20.8-0.80.80.90.90.10.7
Liver weight, left0.71.13.61.21.41.41.60.50.50.6-0.2-1.50.6-0.3-1.5-1.0-1.90.3-0.70.70.90.6-1.30.6
Liver weight, right1.01.74.41.51.81.72.00.60.70.7-0.5-1.80.6-0.4-2.1-1.4-2.00.5-1.21.21.30.9-1.01.1
Locomotor activity1.01.54.20.1-0.3-0.3-0.61.11.00.8-1.10.61.0-1.21.1-0.41.4-1.92.0-2.0-1.9-1.8-0.1-1.4
Locomotor testing distance0.50.93.0-1.0-1.3-1.3-1.5-0.4-0.2-0.10.01.0-0.30.01.70.21.7-0.61.0-1.0-1.0-0.8-0.6-0.8
Locomotor testing rearing0.30.52.6-0.7-1.0-1.0-1.2-0.30.1-0.2-0.50.9-0.3-0.11.0-0.31.6-0.20.5-0.5-0.5-0.4-0.9-0.2
Locomotion in novel chamber0.81.02.60.00.20.10.5-0.8-0.8-1.21.1-0.8-0.71.0-0.90.3-1.61.4-1.41.41.41.30.60.8
Locomotion in novel chamber post-restriction2.32.86.8-1.2-1.0-1.3-0.8-1.9-1.4-1.91.00.7-1.91.7-0.20.40.52.5-2.52.52.62.40.12.1
Fecal boli incidents, locomotor time 10.91.03.3-1.2-1.3-1.1-1.3-0.6-1.1-0.91.30.9-0.60.81.81.30.5-0.40.8-0.8-1.2-1.0-0.2-0.9
Change in fecal boli incidents, locomotor task1.21.13.80.70.90.71.2-0.20.1-0.3-0.2-0.4-0.20.2-1.7-0.5-1.01.4-1.71.71.91.50.31.5
Time >=10cm from walls, locomotor time 10.20.20.90.00.1-0.00.2-0.2-0.2-0.50.2-0.4-0.30.3-0.2-0.3-0.30.6-0.50.50.60.61.00.9
Bouts of movement, locomotor time 10.70.71.4-1.1-1.2-1.1-1.2-0.9-1.1-1.11.00.1-1.11.01.20.60.70.5-0.50.50.00.30.30.4
Total resting periods, locomotor time 10.91.01.9-1.3-1.4-1.4-1.3-1.1-1.3-1.31.10.4-1.31.21.20.80.80.7-0.60.60.10.30.50.5
Rest time, locomotor task time 10.30.30.8-0.8-0.8-0.9-0.8-0.4-0.7-0.80.50.3-0.60.60.70.40.50.2-0.10.1-0.1-0.10.50.4
Distance moved, locomotor task time 10.20.20.8-0.2-0.10.0-0.1-0.6-0.5-0.00.80.3-0.40.60.00.6-0.40.7-0.30.30.60.7-0.9-0.3
Vertical activity count, locomotor time 10.50.51.31.01.01.01.00.40.80.7-0.7-1.00.5-0.6-1.1-0.9-0.70.2-0.30.30.60.7-0.6-0.2
Time >=10cm from walls, locomotor time 22.22.37.42.01.91.62.01.41.81.3-2.1-1.91.3-1.6-2.1-2.7-0.9-0.2-0.40.40.70.4-0.21.2
Bouts of movement, locomotor time 21.21.33.7-0.4-0.5-0.5-0.70.80.40.6-0.51.00.7-0.71.40.61.4-1.81.8-1.8-1.9-1.91.0-1.0
Total resting periods, locomotor time 21.51.64.7-0.3-0.5-0.4-0.61.00.60.6-0.61.00.9-0.91.40.61.3-2.02.1-2.1-2.2-2.10.9-1.2
Rest time, locomotor task time 21.01.23.8-0.5-0.6-0.4-0.60.5-0.1-0.10.40.60.5-0.31.51.10.3-1.51.8-1.8-2.0-1.8-0.7-1.6
Distance moved, locomotor task time 21.21.44.6-0.5-0.3-0.5-0.3-1.3-0.7-0.50.40.2-1.41.0-0.8-0.40.32.0-2.02.02.12.1-0.11.6
Vertical activity count, locomotor time 20.60.72.30.00.0-0.10.0-0.5-0.10.2-0.3-0.5-0.70.4-0.7-0.90.21.2-1.41.41.41.50.91.2
Light reinforcement 10.40.81.8-1.0-1.0-1.1-1.2-1.2-0.7-0.80.30.8-1.20.80.70.31.31.0-0.90.90.60.6-0.20.7
Light reinforcement 20.40.51.2-0.7-0.9-1.0-1.0-1.1-0.5-0.90.20.4-0.90.50.6-0.11.00.8-0.60.60.60.7-0.90.2
Bone: marrow area1.22.65.51.51.21.10.92.32.01.6-2.2-0.61.8-2.1-0.6-1.40.7-2.31.8-1.8-1.9-1.91.1-0.8
Bone: maximum diameter0.30.51.41.11.11.11.20.90.60.5-0.5-1.00.7-0.6-0.9-0.6-1.1-0.40.1-0.1-0.1-0.20.1-0.1
Bone: maximum force1.01.76.11.71.92.02.01.30.91.1-0.4-1.91.2-0.8-1.5-1.1-2.5-0.60.3-0.30.1-0.1-0.7-0.2
Bone: maximum moment1.01.86.31.81.92.02.11.21.01.1-0.5-2.11.2-0.8-1.7-1.3-2.5-0.30.0-0.00.30.1-0.9-0.0
Mean time between licks in bursts2.33.29.10.71.21.11.6-1.0-0.8-0.51.0-1.4-0.81.2-2.4-0.4-2.72.4-2.72.73.02.60.72.2
Mean num. licks in bursts0.70.81.90.30.10.1-0.10.91.00.9-1.40.60.7-1.10.2-0.41.4-1.11.2-1.2-1.3-1.30.7-0.3
Cd content in liver1.21.34.01.41.51.41.60.50.50.6-0.3-2.00.4-0.3-1.8-1.3-1.90.4-1.11.11.21.10.30.7
Co content in liver1.92.26.6-0.10.1-0.00.3-1.5-1.0-1.11.1-0.9-1.31.4-1.1-0.4-1.32.3-2.52.52.62.5-0.71.4
Cu content in liver0.20.30.5-0.4-0.4-0.5-0.4-0.5-0.4-0.70.20.6-0.60.5-0.10.20.60.6-0.60.60.50.50.40.7
Fe content in liver0.81.02.71.31.21.11.11.11.21.0-1.4-1.20.6-0.9-1.4-1.7-0.2-0.30.1-0.10.20.21.30.9
K content in liver1.51.44.3-1.4-1.5-1.4-1.5-0.9-0.5-0.60.52.1-0.30.31.81.51.7-0.10.7-0.7-0.9-0.8-1.9-1.2
Mg content in liver0.30.31.6-0.3-0.3-0.2-0.3-0.10.20.2-0.10.80.3-0.30.60.60.6-0.20.6-0.6-0.6-0.6-1.3-0.8
Mn content in liver1.61.83.8-1.7-1.4-1.5-1.3-1.6-1.8-1.81.81.7-1.51.71.02.00.61.3-0.60.60.50.40.70.9
Na content in liver0.50.53.6-0.5-0.7-0.7-0.9-0.30.50.1-0.91.1-0.1-0.40.6-0.31.9-0.00.2-0.2-0.2-0.1-1.4-0.1
Rb content in liver0.70.83.30.90.91.11.00.90.81.1-0.5-0.61.2-0.9-0.4-0.3-1.0-0.80.6-0.6-0.6-0.7-1.8-1.0
Se content in liver1.41.74.41.51.61.61.80.51.11.1-0.9-1.50.9-0.8-1.9-1.4-1.60.5-1.01.01.10.9-2.10.5
Sr content in liver1.00.91.9-1.2-1.1-1.2-1.1-1.0-1.2-1.41.01.0-1.21.10.80.90.90.7-0.40.40.20.30.80.5
Zn content in liver0.80.92.70.40.40.30.5-0.5-0.1-0.3-0.0-1.3-0.60.4-1.2-1.2-0.71.3-1.51.51.61.6-0.41.1
Bone: minimum diameter0.61.22.81.51.61.61.61.30.90.7-0.6-1.61.1-0.8-1.4-1.0-1.7-0.70.4-0.4-0.2-0.30.40.0
Time in familiar zone, hab. session 10.50.41.30.60.60.50.6-0.10.50.1-0.6-0.80.1-0.2-1.0-1.1-0.40.5-0.80.80.90.8-1.10.4
Time in novel zone, hab. session 10.80.72.9-0.1-0.1-0.1-0.20.80.30.2-0.40.90.6-0.50.60.70.8-1.21.3-1.3-1.3-1.31.7-0.5
Total zone transitions, hab. session 11.11.53.1-1.2-1.1-1.2-1.0-1.7-1.2-1.21.00.6-1.61.40.20.60.61.8-1.61.61.31.4-0.81.1
Total locomotion distance, hab. session 11.21.83.1-1.6-1.5-1.6-1.5-1.6-1.4-1.51.11.8-1.61.40.91.51.31.3-1.01.00.80.90.91.0
Locomotion velocity, hab. session 11.82.54.3-1.9-1.7-1.7-1.5-2.1-1.9-1.61.61.8-2.01.90.91.70.91.9-1.51.51.31.30.11.2
Time in familiar zone, hab. session 20.50.52.4-0.8-1.1-1.2-1.3-0.7-0.3-0.8-0.10.5-0.90.40.6-0.41.60.5-0.30.30.10.40.10.4
Time in novel zone, hab. session 20.90.91.71.11.21.31.21.20.91.2-0.6-0.51.3-1.0-0.5-0.1-0.9-1.10.9-0.9-0.7-0.90.4-0.7
Total zone transitions, hab. session 20.30.41.5-0.7-0.8-0.9-1.0-0.5-0.4-0.70.10.6-0.80.40.50.21.20.4-0.10.1-0.00.10.90.5
Total locomotion distance, hab. session 21.82.37.8-2.0-2.1-2.2-2.2-1.2-1.1-1.50.52.5-1.51.01.71.42.80.50.1-0.1-0.4-0.21.80.7
Locomotion velocity, hab. session 22.23.06.5-2.3-2.3-2.5-2.4-1.7-1.6-1.91.12.5-2.01.51.81.72.61.1-0.40.40.10.31.51.0
Novel to familiar place preference ratio0.10.10.60.20.20.30.30.2-0.2-0.10.5-0.50.20.10.10.3-0.8-0.30.4-0.4-0.5-0.40.4-0.3
Novelty place preference0.20.21.20.40.40.50.50.2-0.1-0.00.4-0.80.30.0-0.20.1-1.1-0.10.1-0.1-0.2-0.10.0-0.3
Time in novel zone, NPP test0.30.31.10.60.70.70.70.60.30.30.0-0.90.6-0.3-0.4-0.2-1.1-0.40.4-0.4-0.5-0.4-0.3-0.4
Total zone transitions, NPP test0.91.33.0-1.6-1.7-1.7-1.7-1.3-1.2-1.20.91.4-1.31.11.31.21.50.8-0.20.20.10.20.10.5
Total locomotion distance, NPP test3.04.19.2-2.8-2.8-2.9-2.9-1.9-2.0-2.01.53.0-2.01.72.52.42.90.80.2-0.2-0.4-0.21.50.5
Locomotion velocity, NPP test3.34.79.1-2.9-2.9-3.0-3.0-2.2-2.4-2.32.03.0-2.32.12.52.72.51.2-0.20.2-0.00.11.40.6
Intraocular pressure0.50.63.1-0.20.10.20.3-0.7-1.2-0.81.6-0.4-0.61.1-0.20.9-1.70.8-0.60.60.60.50.30.2
Delta distance traveled before/after self-admin0.80.82.5-0.5-0.2-0.00.1-1.1-1.2-0.41.60.2-0.81.20.01.1-1.21.3-1.11.11.21.0-0.60.5
Delta ambulatory time before/after self-admin0.70.83.0-0.6-0.2-0.10.0-1.0-1.3-0.61.70.3-0.71.30.11.3-1.21.1-0.90.90.90.8-0.40.2
Parametrial fat weight12.524.340.76.26.05.95.76.36.45.9-6.2-4.56.1-6.2-4.7-5.3-2.6-4.83.1-3.1-2.7-3.0-1.0-2.0
Pavlov. Cond. lever latency0.40.62.60.90.90.80.80.90.70.5-0.8-1.00.4-0.6-1.0-1.1-0.2-0.40.1-0.1-0.0-0.11.60.7
Pavlov. Cond. magazine entry latency0.81.12.51.11.01.11.01.21.31.4-1.2-0.51.4-1.4-0.5-0.6-0.4-1.10.8-0.8-0.8-0.8-1.6-1.0
Pavlov. Cond. change in total contacts0.20.21.3-0.3-0.10.00.1-0.2-0.20.00.50.70.30.10.41.1-0.40.00.1-0.1-0.1-0.2-1.0-0.6
Pavlov. Cond. index score0.20.33.00.20.20.30.30.10.40.6-0.10.10.6-0.40.10.2-0.4-0.20.3-0.3-0.2-0.2-1.7-0.8
Pavlov. Cond. latency score0.20.22.7-0.3-0.3-0.1-0.1-0.4-0.2-0.00.40.40.10.20.40.6-0.30.2-0.10.10.10.1-1.7-0.6
Pavlov. Cond. lever contacts0.30.31.1-0.5-0.5-0.4-0.5-0.1-0.10.10.21.10.2-0.10.80.90.5-0.40.5-0.5-0.6-0.6-0.9-0.9
Pavlov. Cond. magazine entry number1.31.63.1-1.4-1.4-1.5-1.4-1.6-1.5-1.71.20.8-1.81.60.70.60.91.4-1.11.11.01.11.31.2
Pavlov. Cond. intertrial magazine entries1.41.75.3-1.4-1.2-1.4-1.1-1.3-1.6-1.61.51.2-1.61.60.81.30.61.2-0.70.70.70.72.31.3
Pavlov. Cond. lever-magazine prob. diff.0.30.42.70.20.20.30.20.30.50.7-0.40.10.8-0.60.20.2-0.1-0.50.6-0.6-0.6-0.5-1.6-1.0
Pavlov. Cond. response bias0.70.91.80.80.91.00.81.11.11.2-0.9-0.21.3-1.2-0.3-0.1-0.4-1.10.9-0.9-0.9-0.9-1.1-1.0
Pavlov. Cond. lever latency2.23.06.6-1.9-1.7-1.5-1.5-2.5-2.3-1.92.60.8-2.02.31.21.6-0.32.1-1.51.51.41.5-1.60.5
Pavlov. Cond. magazine entry latency0.60.71.90.90.60.50.41.21.10.9-1.4-0.80.7-1.1-0.5-1.40.4-1.10.7-0.7-0.8-0.70.5-0.2
Pavlov. Cond. change in total contacts2.73.79.01.91.71.51.32.82.62.2-3.0-0.52.1-2.6-1.2-1.70.9-2.31.9-1.9-1.7-1.82.0-0.3
Pavlov. Cond. index score2.22.86.51.91.61.51.42.42.31.9-2.5-1.01.9-2.2-1.3-1.90.2-2.01.3-1.3-1.3-1.31.1-0.4
Pavlov. Cond. latency score1.51.84.41.51.31.21.11.91.81.5-2.1-0.91.5-1.8-1.1-1.60.2-1.61.0-1.0-1.0-1.01.1-0.3
Pavlov. Cond. lever contacts1.92.76.61.71.51.31.22.32.31.8-2.6-0.61.9-2.3-1.0-1.60.6-2.01.5-1.5-1.4-1.51.3-0.5
Pavlov. Cond. magazine entry number1.21.53.2-1.4-1.2-1.1-1.0-1.8-1.6-1.41.81.0-1.31.60.91.6-0.01.5-1.01.01.01.0-0.60.3
Pavlov. Cond. intertrial magazine entries0.30.31.0-0.8-0.7-0.6-0.6-0.6-0.8-0.60.90.7-0.50.70.81.00.10.30.1-0.10.00.10.5-0.1
Pavlov. Cond. lever-magazine prob. diff.2.63.37.62.11.81.71.62.52.52.1-2.8-1.22.1-2.5-1.4-2.10.1-2.11.4-1.4-1.3-1.40.8-0.5
Pavlov. Cond. response bias1.92.65.51.71.51.41.32.32.11.8-2.3-0.91.8-2.1-1.0-1.60.3-2.01.5-1.5-1.4-1.51.4-0.5
Time in closed arm before self-admin0.10.10.4-0.1-0.0-0.00.0-0.4-0.5-0.20.6-0.0-0.40.5-0.1-0.1-0.50.5-0.60.60.50.4-0.00.0
Time in closed arm after self-admin2.22.34.8-1.4-1.1-1.3-0.9-1.9-1.9-2.21.91.1-1.81.90.51.4-0.12.0-1.81.81.61.40.31.1
Time in open arm before self-admin0.40.42.20.20.1-0.1-0.10.50.90.6-1.50.50.3-0.8-0.3-0.81.4-0.30.3-0.3-0.00.10.60.6
Time in open arm after self-admin1.41.53.91.41.41.31.21.71.82.0-2.0-0.91.4-1.6-1.2-1.50.1-1.10.6-0.6-0.4-0.40.30.1
Bone: periosteal estimation1.02.03.81.91.91.81.81.91.61.4-1.5-1.71.6-1.5-1.4-1.5-1.1-1.30.9-0.9-0.7-0.80.4-0.4
Bone: periosteal perimeter0.20.32.50.70.70.60.70.70.30.1-0.4-0.70.2-0.2-0.8-0.6-0.3-0.20.1-0.10.1-0.01.60.7
Bone: post-yield work0.60.82.61.01.00.80.80.90.90.6-1.1-1.30.4-0.7-1.2-1.5-0.1-0.20.0-0.00.30.31.60.8
Progressive ratio test 1 active lever presses0.20.20.4-0.5-0.5-0.6-0.5-0.4-0.4-0.60.30.6-0.50.40.40.30.50.2-0.20.20.10.1-0.00.2
Progressive ratio test 1 breakpoint0.10.10.4-0.4-0.4-0.4-0.4-0.2-0.3-0.40.30.6-0.30.30.40.40.3-0.00.0-0.0-0.1-0.1-0.10.1
Progressive ratio test 1 inactive lever presses0.30.41.5-0.7-0.9-1.0-0.9-0.4-0.2-0.9-0.00.9-0.40.10.80.41.2-0.10.4-0.4-0.4-0.40.2-0.1
Progressive ratio test 2 active lever presses0.10.10.5-0.3-0.5-0.5-0.6-0.2-0.0-0.5-0.20.3-0.40.10.4-0.40.70.00.1-0.1-0.00.10.10.1
Progressive ratio test 2 breakpoint0.10.10.3-0.2-0.4-0.4-0.50.00.1-0.3-0.20.2-0.1-0.10.4-0.30.6-0.30.4-0.4-0.3-0.2-0.1-0.2
Progressive ratio test 2 inactive lever presses0.20.31.30.3-0.1-0.3-0.40.30.7-0.4-1.0-0.30.1-0.60.1-1.21.1-0.40.5-0.5-0.4-0.20.2-0.1
Incentive Sensitization - Responses0.20.30.8-0.1-0.2-0.4-0.3-0.30.0-0.5-0.40.1-0.50.1-0.2-0.70.60.6-0.60.60.70.80.20.9
Incentive Sensitization - Breakpoint0.30.30.7-0.2-0.4-0.5-0.4-0.4-0.0-0.6-0.40.3-0.60.2-0.0-0.60.80.6-0.60.60.70.70.20.8
Sum of active levers in priming session hrs 5-60.60.61.2-0.9-0.8-0.8-0.6-1.1-0.9-1.00.80.9-0.80.90.41.00.31.0-0.70.70.50.4-0.20.5
Progressive ratio1.82.13.9-1.5-1.4-1.6-1.1-2.0-1.6-2.01.30.7-1.81.70.51.00.72.0-1.51.51.61.60.51.6
Food seeking constrained by brief footshock3.13.87.9-2.8-2.7-2.6-2.8-2.2-2.3-1.72.12.5-2.32.22.52.12.11.1-0.30.30.40.6-0.20.3
Seeking ratio, punishment vs. effort0.81.02.70.1-0.10.1-0.51.00.61.2-0.60.70.7-0.81.0-0.00.9-1.61.5-1.5-1.7-1.5-0.4-1.6
Retroperitoneal fat weight14.848.581.99.09.09.08.78.68.58.6-7.7-6.98.6-8.2-7.0-7.0-5.7-6.23.6-3.6-3.1-3.7-2.4-2.6
Reaction time number correct0.40.51.4-0.8-0.8-0.7-0.8-0.4-0.8-0.80.91.0-0.40.51.01.20.4-0.20.7-0.7-0.6-0.60.3-0.6
Reaction time mean minus median1.11.43.71.41.41.21.41.51.71.5-1.9-0.81.5-1.7-1.4-1.5-0.2-1.00.4-0.4-0.3-0.6-0.10.1
Reaction time mean minus median AUC0.91.22.41.31.41.21.41.01.41.3-1.6-0.81.2-1.3-1.5-1.4-0.6-0.4-0.10.10.1-0.1-1.30.2
Reaction time num false alarms2.02.75.6-1.1-0.9-1.0-0.7-2.0-2.1-1.92.1-0.6-2.22.30.10.5-0.72.4-2.02.02.02.10.81.7
Reaction time num false alarms AUC1.62.24.2-1.2-1.1-1.1-0.9-1.9-1.9-1.72.0-0.2-2.02.00.40.6-0.32.1-1.71.71.61.80.41.3
Reaction time trials correct on left0.40.51.4-0.8-0.8-0.7-0.8-0.4-0.8-0.80.91.0-0.40.51.01.20.4-0.20.7-0.7-0.6-0.60.3-0.6
Reaction time trials on left0.40.51.5-0.8-0.8-0.7-0.8-0.3-0.7-0.80.91.1-0.30.51.11.20.4-0.30.7-0.7-0.7-0.70.3-0.6
Reaction time mean2.02.76.91.71.41.31.32.22.42.1-2.6-0.92.1-2.4-1.0-2.00.3-2.01.4-1.4-1.3-1.3-0.1-0.7
Reaction time mean AUC1.82.45.81.71.51.41.32.02.22.0-2.4-1.01.9-2.2-1.1-2.00.0-1.71.1-1.1-1.0-1.1-0.1-0.5
Median of all reaction times1.72.35.91.51.21.10.92.02.21.9-2.4-0.71.9-2.2-0.6-1.80.5-1.91.5-1.5-1.4-1.3-0.1-0.9
Reaction time omissions0.40.52.90.60.70.60.70.71.01.1-1.20.50.8-1.0-0.6-0.40.2-0.4-0.10.1-0.0-0.3-1.7-0.0
Reaction time false alarm rate1.31.84.0-0.8-0.7-0.8-0.6-1.7-1.5-1.21.5-0.6-1.71.7-0.10.1-0.42.0-1.91.91.82.00.21.4
Reaction time premature initiation rate0.30.30.9-0.1-0.1-0.1-0.0-0.8-0.6-0.50.6-0.5-0.60.7-0.1-0.1-0.51.0-0.80.80.80.8-0.70.4
Reaction time premature initiations0.30.41.2-0.6-0.6-0.6-0.5-1.0-1.0-1.01.10.2-0.80.90.60.7-0.10.8-0.40.40.30.4-0.60.1
Std. dev. reaction times1.52.14.91.61.51.41.41.92.12.0-2.2-0.81.8-2.0-1.3-1.5-0.1-1.50.9-0.9-0.9-1.0-0.1-0.3
Reaction time trials completed0.40.51.5-0.8-0.8-0.7-0.8-0.3-0.7-0.80.91.1-0.30.51.11.20.4-0.30.7-0.7-0.7-0.70.3-0.6
Reaction time trials AUC0.40.51.3-0.7-0.7-0.6-0.7-0.2-0.6-0.70.71.0-0.20.41.01.10.4-0.40.9-0.9-0.9-0.80.5-0.6
Run reversals in cocaine runway, females0.70.71.61.21.01.00.81.11.10.9-1.1-0.90.8-1.0-0.9-1.3-0.4-0.80.4-0.4-0.5-0.3-0.3-0.4
Run reversals in cocaine runway, males1.21.13.20.70.60.80.51.40.81.3-0.6-0.31.2-1.00.2-0.1-0.3-1.71.5-1.5-1.8-1.60.2-1.3
Latency to leave start box in cocaine runway0.91.02.20.80.70.50.7-0.20.3-0.1-0.5-1.5-0.30.0-1.3-1.4-0.51.1-1.41.41.41.41.41.4
Latency to leave start box in cocaine runway, F1.61.75.81.71.61.41.60.60.90.4-0.9-2.40.4-0.6-2.0-2.0-1.40.6-1.01.01.11.21.21.0
Latency to leave start box in cocaine runway, M0.90.82.2-1.1-1.2-1.3-1.2-1.1-0.7-0.90.30.9-1.10.70.70.31.51.0-0.60.60.60.60.80.8
Std. dev. time between licks in bursts1.31.63.9-0.4-0.0-0.10.2-1.4-1.3-1.01.5-0.1-1.21.5-0.70.6-1.51.9-1.91.92.01.80.11.2
Total sessions with >9 infusions0.50.61.4-0.8-1.0-1.1-1.0-0.9-0.7-1.20.40.4-1.10.80.50.10.90.8-0.60.60.50.60.50.7
Short access day 1 total inactive lever presses0.70.82.0-0.2-0.3-0.4-0.2-0.9-0.6-1.00.4-0.6-1.10.8-0.2-0.70.01.4-1.41.41.41.40.11.2
Short access day 10 total inactive lever presses1.31.52.51.51.41.41.31.61.61.5-1.5-1.11.6-1.6-0.9-1.2-0.7-1.30.9-0.9-0.7-0.9-0.3-0.5
Short access day 1 total infusions1.71.83.6-1.5-1.6-1.8-1.6-1.7-1.4-1.91.10.8-1.81.51.10.61.31.6-1.21.21.11.20.21.2
Short access day 10 total infusions0.40.51.1-0.9-0.9-0.9-0.9-0.8-0.8-1.00.80.7-0.70.70.80.70.40.4-0.10.1-0.10.0-0.1-0.0
Short access total infusions0.30.30.9-0.6-0.6-0.7-0.6-0.7-0.6-0.90.40.4-0.80.60.30.30.40.7-0.60.60.60.60.20.6
Short access day 1 locomotion1.31.32.9-1.5-1.6-1.7-1.6-1.3-1.1-1.40.71.4-1.31.01.11.01.70.9-0.60.60.50.50.50.8
Short access day 10 total locomotion1.92.15.9-1.9-2.2-2.2-2.4-1.1-1.1-1.50.71.7-1.10.82.31.02.3-0.20.9-0.9-1.0-0.60.1-0.4
Short access total locomotion2.02.16.1-2.0-2.2-2.2-2.4-1.2-1.1-1.40.71.8-1.30.92.21.22.50.00.6-0.6-0.6-0.40.4-0.2
One hour access (0.3 mA shock)1.31.54.1-1.7-1.9-1.9-2.0-1.2-1.1-1.40.81.3-1.41.01.50.81.90.50.1-0.1-0.10.20.40.2
Compulsive drug intake0.70.71.1-0.9-0.8-0.8-0.6-1.0-1.0-1.00.91.1-0.91.00.31.10.31.0-0.70.70.80.60.30.7
One hour access (shock baseline)0.10.10.60.2-0.0-0.1-0.20.10.20.0-0.4-0.4-0.1-0.20.0-0.80.3-0.10.1-0.1-0.10.20.10.1
Social response proportion4.54.910.42.42.12.21.72.92.93.2-2.9-1.82.6-2.9-1.1-2.6-0.2-2.71.9-1.9-1.9-1.8-0.4-1.3
Social responses0.30.31.10.0-0.00.1-0.10.60.30.9-0.30.10.4-0.50.50.00.5-0.90.8-0.8-1.1-1.0-0.1-0.5
Social time0.71.02.60.90.60.60.41.11.21.5-1.4-1.11.0-1.2-0.2-1.60.3-1.10.9-0.9-1.0-0.8-1.0-0.7
Soleus weight0.10.40.90.90.80.80.80.70.70.5-0.7-0.80.6-0.6-0.9-0.8-0.6-0.4-0.00.0-0.1-0.1-0.6-0.1
Bone: stiffness0.50.74.41.01.31.31.40.70.10.30.3-1.40.5-0.1-1.1-0.4-2.1-0.1-0.10.10.30.10.20.2
Tibialis anterior weight1.34.59.22.62.52.42.32.73.02.7-3.0-1.72.6-2.8-2.1-2.5-0.7-1.91.0-1.0-0.9-1.0-0.9-0.6
Time to tail flick, vehicle, before self-admin4.04.110.52.93.02.73.11.92.31.4-2.2-2.32.0-2.0-3.2-2.4-2.2-0.4-0.50.50.60.2-0.10.4
Time to tail flick, vehicle, after self-admin0.10.10.30.30.40.40.50.30.30.2-0.10.30.5-0.3-0.20.5-0.5-0.20.2-0.2-0.3-0.4-0.0-0.2
Time to tail flick, test, before self-admin0.10.10.20.0-0.1-0.1-0.1-0.2-0.0-0.2-0.1-0.4-0.30.1-0.3-0.50.10.4-0.40.40.30.40.50.2
Time to tail flick, test, after self-admin0.20.21.4-0.0-0.3-0.3-0.2-0.5-0.3-1.20.3-1.0-0.40.30.0-0.7-0.20.6-0.20.20.10.3-0.3-0.0
Delta time to tail flick, vehicle, before/after SA1.61.64.5-1.7-1.6-1.5-1.5-1.3-1.6-1.11.71.7-1.11.41.92.10.70.50.1-0.1-0.2-0.10.1-0.2
Delta time to tail flick, test, before/after SA0.20.20.5-0.4-0.6-0.6-0.7-0.2-0.1-0.60.10.2-0.10.00.70.10.6-0.20.6-0.6-0.6-0.5-0.3-0.4
Tibia length3.910.925.84.54.84.84.93.12.93.2-2.3-5.12.8-2.4-4.7-3.9-4.8-0.8-0.60.61.00.7-1.10.8
Ambulatory time before self-admin0.60.61.70.20.10.00.00.81.00.8-1.30.90.9-1.10.2-0.31.1-1.10.9-0.9-0.9-1.1-0.3-0.4
Ambulatory time after self-admin0.50.52.2-0.9-0.6-0.5-0.5-0.7-0.9-0.31.21.3-0.50.80.81.5-0.30.4-0.20.20.1-0.1-0.8-0.3
Bone: tissue strength0.50.51.10.90.90.80.81.00.80.8-0.8-0.50.7-0.8-0.7-0.7-0.3-0.70.7-0.7-0.5-0.60.90.2
Total heroin consumption0.10.10.6-0.2-0.2-0.4-0.2-0.4-0.1-0.8-0.10.4-0.30.1-0.2-0.00.40.4-0.40.40.40.3-0.20.5
Bone: trabecular number1.11.75.00.10.20.10.4-1.1-0.8-0.80.8-1.2-1.21.2-1.3-0.7-1.41.9-2.12.12.22.1-0.21.6
Bone: trabecular spacing1.52.04.51.00.91.10.91.81.31.6-0.9-0.11.9-1.50.20.1-0.4-2.12.0-2.0-2.1-2.10.1-1.7
Bone: trabecular thickness1.82.15.20.91.00.91.1-0.70.2-0.1-0.2-1.7-0.30.2-1.8-1.6-1.71.7-2.22.22.32.2-2.21.2
Bone: trabecular tissue density0.30.50.80.90.90.90.80.80.90.9-0.8-0.80.8-0.8-0.6-0.8-0.5-0.60.4-0.4-0.2-0.10.1-0.2
Water consumed over 24 hours0.10.10.50.10.1-0.0-0.0-0.10.0-0.2-0.1-0.7-0.20.1-0.3-0.60.10.3-0.30.30.20.3-0.30.3
Number of responses in last shaping day1.41.42.6-1.3-1.3-1.5-1.3-1.4-1.3-1.61.00.4-1.61.40.70.61.01.4-1.21.21.01.00.81.1