Best TWAS P=2.257842e-07 · Best GWAS P=3.248939e-06 conditioned to 0.2194713
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Prp2l1 | intron excision ratio | chr10:88469122:88493568 | 0.11 | 0.03 | lasso | 31 | 0.06 | 1.3e-06 | 3.9 | 5.2 | 2.3e-07 | -0.74 | 0.54 | 0.44 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.