Hub : Traits : Body weight : ← : →

chr8:117,463,629-120,978,811

Trait: Body weight

Best TWAS P = 1.92e-10 · Best GWAS P= 1.40e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Mlh1	alternative polyA	NM_031053.2	0.02	1	0.01	9.2e-03	5.4	6.55e-08	0.06	FALSE
Adipose	Mlh1	alternative polyA	XM_063266207.1	0.02	1	0.01	8.7e-03	-5.4	6.55e-08	0.06	FALSE
Adipose	Mlh1	alternative polyA	NM_031053.2	0.02	1	0.01	1.1e-02	5.4	6.55e-08	0.06	FALSE
Adipose	Mlh1	alternative polyA	XM_063266207.1	0.02	1	0.01	9.9e-03	-5.4	6.55e-08	0.06	FALSE
Adipose	Als2cl	gene expression	Als2cl	0.24	2807	0.01	1.8e-02	5.62	1.86e-08	0.25	FALSE
Adipose	Ccrl2	gene expression	Ccrl2	0.03	1	0.01	8.4e-03	-5.37	7.88e-08	0.03	FALSE
Adipose	Mlh1	isoform ratio	XM_063266207.1	0.03	1	0.01	9.7e-03	-5.43	5.63e-08	0.06	FALSE
BLA	Lrrfip2	gene expression	Lrrfip2	0.07	1	0.07	2.0e-04	-5.52	3.38e-08	0.17	FALSE
Brain	Pth1r	alternative TSS	XM_006244002.4	0.08	163	0.05	4.0e-05	-5.38	7.37e-08	0.41	FALSE
Brain	Nbeal2	gene expression	Nbeal2	0.61	2768	0.32	7.6e-31	5.21	1.85e-07	0.48	FALSE
Brain	Ccdc12	intron excision ratio	chr8_119547056_119561689	0.05	18	0.05	1.1e-05	-5.27	1.39e-07	0.23	FALSE
Brain	Mlh1	intron excision ratio	chr8_120095325_120096995	0.02	1	0.03	8.1e-04	5.46	4.75e-08	0.05	FALSE
Brain	Trank1	intron excision ratio	chr8_120219593_120222781	0.06	1	0.06	1.4e-06	-5.29	1.26e-07	0.39	TRUE
Brain	Trank1	intron excision ratio	chr8_120221634_120222781	0.02	1	0.02	6.2e-03	5.28	1.29e-07	0.03	FALSE
IC	Kif9	alternative polyA	NM_001192000.2	0.47	1	0.17	8.2e-08	-5.27	1.38e-07	0.56	FALSE
IC	Kif9	alternative polyA	XM_006243994.5	0.52	1	0.18	5.7e-08	5.27	1.38e-07	0.58	FALSE
IC	Epm2aip1	gene expression	Epm2aip1	0.13	39	0.15	1.1e-06	-5.26	1.43e-07	0.34	FALSE
IC	Mlh1	gene expression	Mlh1	0.48	27	0.51	1.8e-24	5.37	7.81e-08	0.31	FALSE
IL	Dclk3	gene expression	Dclk3	0.29	81	0.17	8.7e-05	-5.25	1.53e-07	0.42	FALSE
IL	Mlh1	gene expression	Mlh1	0.55	678	0.44	8.5e-12	5.27	1.34e-07	0.4	FALSE
IL	Mlh1	mRNA stability	Mlh1	0.24	1	0.1	2.1e-03	5.4	6.55e-08	0.05	FALSE
LHb	Ccdc12	gene expression	Ccdc12	0.49	2646	0.16	1.1e-04	-5.7	1.20e-08	0.34	TRUE
Liver	Pth1r	alternative polyA	XM_039082024.2	0.06	31	0.05	2.4e-06	-5.31	1.12e-07	0.37	FALSE
Liver	Pth1r	alternative polyA	XM_006243999.4	0.06	25	0.05	1.7e-06	-5.24	1.57e-07	0.37	FALSE
Liver	Mlh1	gene expression	Mlh1	0.55	930	0.6	2.0e-84	5.34	9.55e-08	0.48	FALSE
Liver	Mst1	isoform ratio	NM_024352.1	0.07	224	0.06	1.2e-07	-6.37	1.92e-10	0	TRUE
Liver	Pth1r	isoform ratio	NM_020073.2	0.07	12	0.07	3.9e-08	5.21	1.88e-07	0.4	FALSE
Liver	Mlh1	mRNA stability	Mlh1	0.02	7	0.02	1.7e-03	5.32	1.01e-07	0.4	FALSE
Liver	Pth1r	mRNA stability	Pth1r	0.05	1	0.03	6.2e-04	5.37	7.88e-08	0.15	FALSE
Liver	Rtp3	mRNA stability	Rtp3	0.03	1	0.02	5.4e-03	-5.48	4.37e-08	0.05	FALSE
NAcc	Lrrfip2	gene expression	Lrrfip2	0.09	92	0.14	7.2e-21	-5.23	1.67e-07	0.52	FALSE
NAcc	Trank1	gene expression	Trank1	0.02	1	0.03	1.1e-05	5.38	7.54e-08	0.42	FALSE
NAcc	Lrrfip2	intron excision ratio	chr8_119970179_119989208	0.04	9	0.05	3.8e-08	5.28	1.31e-07	0.34	FALSE
NAcc	Trank1	intron excision ratio	chr8_120219593_120221549	0.02	1	0.02	2.3e-04	5.29	1.25e-07	0.27	FALSE
OFC	Epm2aip1	gene expression	Epm2aip1	0.24	8	0.14	4.1e-04	-5.36	8.51e-08	0.36	FALSE
PL	Mlh1	isoform ratio	XR_005487930.2	0.04	1	0.05	3.1e-06	5.38	7.54e-08	0.5	FALSE
PL	Map4	intron excision ratio	chr8_118869628_118893840	0.4	148	0.03	2.6e-04	5.42	5.86e-08	0.49	FALSE
pVTA	Map4	alternative TSS	NM_001419954.1	0.48	81	0.12	1.6e-09	5.21	1.86e-07	0.55	FALSE
pVTA	LOC102552504	intron excision ratio	chr8_119957747_119958158	0.03	1	0.03	1.1e-03	5.29	1.25e-07	0.04	FALSE
pVTA	LOC102552504	intron excision ratio	chr8_119957747_119958652	0.03	3	0.02	7.8e-03	-5.27	1.38e-07	0.3	FALSE
RMTg	Mlh1	gene expression	Mlh1	0.33	1	0.29	2.5e-08	5.26	1.48e-07	0.21	FALSE