Best TWAS P = 2.95e-09 · Best GWAS P= 1.14e-07 conditioned to 7.80e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Tars3 | gene expression | Tars3 | 0.38 | 30 | 0.32 | 1.8e-36 | -5.21 | 1.91e-07 | 0.82 | FALSE |
| Adipose | Tars3 | mRNA stability | Tars3 | 0.59 | 1 | 0.5 | 4.6e-63 | -5.23 | 1.72e-07 | 0.86 | FALSE |
| BLA | Tars3 | gene expression | Tars3 | 0.61 | 42 | 0.5 | 1.0e-29 | -5.49 | 4.12e-08 | 0.81 | FALSE |
| Brain | Tars3 | gene expression | Tars3 | 0.65 | 90 | 0.61 | 4.5e-72 | -5.47 | 4.45e-08 | 0.8 | FALSE |
| Brain | Tars3 | mRNA stability | Tars3 | 0.51 | 221 | 0.52 | 5.3e-56 | -5.41 | 6.20e-08 | 0.82 | FALSE |
| IL | Tars3 | gene expression | Tars3 | 0.7 | 1978 | 0.53 | 7.7e-15 | -5.93 | 2.95e-09 | 0.78 | TRUE |
| NAcc | Tars3 | gene expression | Tars3 | 0.57 | 48 | 0.53 | 3.9e-96 | -5.57 | 2.52e-08 | 0.81 | FALSE |
| PL | Tars3 | gene expression | Tars3 | 0.65 | 47 | 0.7 | 2.1e-107 | -5.52 | 3.35e-08 | 0.83 | FALSE |
| PL | Tars3 | mRNA stability | Tars3 | 0.19 | 51 | 0.22 | 6.9e-24 | -5.4 | 6.85e-08 | 0.83 | FALSE |