Hub : Traits : Body weight : ← : →

chr8:94,532,832-97,936,197

Trait: Body weight

Best TWAS P=1.98e-10 · Best GWAS P=1.70e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	LOC102551788	gene expression	LOC102551788	0.17	8	0.08	2.5e-09	-5.28	1.27e-07	0.03	TRUE
Adipose	Trpc1	gene expression	Trpc1	0.08	2010	0.05	3.2e-06	5.4	6.85e-08	0.78	FALSE
Adipose	Trpc1	intron excision ratio	chr8_96280099_96282351	0.04	2010	0.03	1.5e-04	5.39	7.16e-08	0.76	FALSE
BLA	Rasa2	alternative polyA	NM_001105724.1	0.07	1879	0.03	9.7e-03	6.03	1.67e-09	0.65	FALSE
BLA	Rasa2	alternative polyA	XM_039080892.1	0.08	1879	0.05	1.4e-03	-5.98	2.17e-09	0.7	FALSE
BLA	Rasa2	alternative polyA	NM_001105724.1	0.07	1879	0.02	1.8e-02	5.58	2.40e-08	0.56	FALSE
BLA	Rasa2	alternative polyA	XM_039080892.1	0.08	1879	0.05	1.5e-03	-5.42	5.92e-08	0.51	TRUE
BLA	Rasa2	gene expression	Rasa2	0.11	1879	0.08	5.5e-05	5.89	3.89e-09	0.28	FALSE
BLA	Trpc1	intron excision ratio	chr8_96280099_96282351	0.07	1	0.06	6.9e-04	-5.25	1.52e-07	0.08	FALSE
BLA	Atp1b3	mRNA stability	Atp1b3	0.07	1	0.08	7.3e-05	-5.47	4.43e-08	0.17	FALSE
Brain	Tfdp2	alternative TSS	XM_039081179.1	0.03	1808	0.01	1.4e-02	5.38	7.63e-08	0.54	FALSE
Brain	Atp1b3	gene expression	Atp1b3	0.09	4	0.04	1.7e-04	6.13	8.98e-10	0.58	TRUE
Brain	Chst2	gene expression	Chst2	0.29	2201	0.17	1.3e-15	5.39	6.98e-08	0.07	FALSE
Brain	Tfdp2	intron excision ratio	chr8_96795874_96804811	0.06	1808	0.04	2.4e-04	-6.28	3.30e-10	0.25	FALSE
Brain	Trpc1	intron excision ratio	chr8_96280099_96280911	0.13	2015	0.1	2.1e-09	-5.81	6.40e-09	0.81	FALSE
Brain	Trpc1	intron excision ratio	chr8_96280099_96282351	0.18	261	0.17	2.6e-15	-5.81	6.42e-09	0.76	FALSE
Brain	Atp1b3	mRNA stability	Atp1b3	0.46	22	0.43	4.6e-43	5.48	4.23e-08	0.61	FALSE
Brain	Gk5	mRNA stability	Gk5	0.06	6	0.03	6.8e-04	5.2	1.98e-07	0.65	FALSE
Brain	Pls1	mRNA stability	Pls1	0.18	1938	0.14	5.0e-13	-6.36	1.98e-10	0.77	TRUE
Brain	Trpc1	mRNA stability	Trpc1	0.14	2015	0.12	7.9e-11	5.31	1.11e-07	0.72	FALSE
LHb	PCOLCE2	gene expression	PCOLCE2	0.35	15	0.18	5.4e-05	5.2	2.00e-07	0.72	FALSE
Liver	PCOLCE2	gene expression	PCOLCE2	0.09	1	0.08	2.4e-09	-5.41	6.47e-08	0.9	FALSE
Liver	Atp1b3	mRNA stability	Atp1b3	0.06	2	0.04	5.0e-05	5.34	9.50e-08	0.74	TRUE
NAcc	LOC102552777	alternative polyA	XR_005488673.1	0.05	72	0.03	3.4e-04	-5.87	4.41e-09	0.68	TRUE
NAcc	Trpc1	intron excision ratio	chr8_96280099_96282351	0.12	2015	0.11	2.0e-12	5.87	4.45e-09	0.79	FALSE
NAcc	Trpc1	intron excision ratio	chr8_96280967_96282351	0.12	6	0.15	1.6e-16	-5.5	3.77e-08	0.8	FALSE
NAcc	Atp1b3	mRNA stability	Atp1b3	0.11	32	0.14	2.0e-15	5.39	6.95e-08	0.78	FALSE
OFC	U2surp	alternative polyA	XM_039082560.1	0.27	1	0.03	5.9e-02	-5.19	2.06e-07	0.06	TRUE
OFC	Rnf7	gene expression	Rnf7	0.46	22	0.11	1.2e-03	5.25	1.52e-07	0.49	FALSE
PL	Tfdp2	alternative polyA	NM_001106847.2	0.16	39	0.19	8.8e-21	5.49	3.94e-08	0.63	FALSE
PL	Tfdp2	alternative polyA	XM_017595585.2	0.16	28	0.18	1.2e-19	-5.35	9.04e-08	0.65	FALSE
PL	Trpc1	intron excision ratio	chr8_96280099_96282351	0.04	1	0.04	2.0e-05	-5.18	2.16e-07	0.3	FALSE
PL	Atp1b3	mRNA stability	Atp1b3	0.13	1	0.18	1.3e-19	-5.47	4.43e-08	0.77	FALSE
pVTA	Tfdp2	isoform ratio	NM_001106847.2	0.07	1	0.05	2.7e-03	5.45	5.16e-08	0.05	FALSE
pVTA	Trpc1	intron excision ratio	chr8_96280099_96282351	0.14	1	0.1	3.0e-05	-5.25	1.52e-07	0.17	FALSE
pVTA	Trpc1	intron excision ratio	chr8_96280967_96282351	0.12	1	0.11	1.9e-05	5.21	1.91e-07	0.1	FALSE