Best TWAS P=6.266195e-09 · Best GWAS P=3.8035e-09 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NAcc | Pacrgl | mRNA stability | ENSRNOG00000004140 | 0.2 | 0 | enet | 67 | 0.02 | 0.13 | 3.1 | 5.8 | 6.3e-09 | 0.96 | 0.34 | 0.12 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.