LOC120101719

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr3_130525654_130567132 0.13 0.06 0.0e+00 0.19 0.2 0.2 0.16 5.0e-17 2.7e-18 2.1e-18 5.9e-15
2 NAcc alternative polyA XR_005502514.1 0.11 0.06 1.9e-15 0.15 0.14 0.13 0.14 1.4e-16 1.4e-15 1.8e-14 3.7e-16
3 NAcc isoform ratio XR_005502514.1 0.12 0.07 1.3e-12 0.13 0.12 0.11 0.13 3.4e-15 3.5e-13 1.2e-12 1.5e-14
4 PL intron excision ratio chr3_130525654_130567132 0.26 0.09 0.0e+00 0.4 0.4 0.39 0.4 3.9e-47 1.5e-46 6.1e-46 4.1e-47
5 IL intron excision ratio chr3_130525654_130567132 0.32 0.16 1.6e-04 0.13 0.09 0.09 0.01 5.8e-04 3.9e-03 3.9e-03 1.9e-01
6 OFC isoform ratio XR_005502514.1 0.38 0.15 9.0e-08 0.26 0.25 0.24 0.24 5.6e-07 1.0e-06 1.8e-06 2.2e-06
7 PL alternative polyA XR_005502514.1 0.3 0.12 0.0e+00 0.35 0.34 0.34 0.34 2.0e-39 3.3e-38 7.2e-39 6.2e-39
8 PL alternative polyA XR_005502515.1 0.34 0.12 0.0e+00 0.36 0.36 0.36 0.36 4.9e-42 2.1e-41 1.2e-41 9.5e-42
9 PL intron excision ratio chr3_130529471_130567132 0.13 0.07 0.0e+00 0.22 0.19 0.19 0.2 1.2e-23 1.9e-20 9.4e-21 3.5e-22
10 IL gene expression LOC120101719 0.19 0.11 5.4e-04 0.08 0.05 0.03 0.01 5.1e-03 2.7e-02 7.9e-02 1.5e-01
11 OFC gene expression LOC120101719 0.18 0.1 9.4e-05 0.22 0.17 0.17 0.17 7.2e-06 7.7e-05 8.0e-05 8.1e-05
12 PL isoform ratio XR_005502514.1 0.43 0.13 0.0e+00 0.41 0.39 0.41 0.4 1.1e-47 5.2e-46 5.9e-48 1.4e-46
13 OFC alternative polyA XR_005502515.1 0.35 0.14 7.9e-08 0.26 0.26 0.29 0.28 9.2e-07 6.4e-07 1.6e-07 2.3e-07
14 IL alternative polyA XR_005502514.1 0.24 0.11 7.4e-07 0.25 0.24 0.27 0.26 8.5e-07 1.8e-06 4.2e-07 6.8e-07
15 OFC alternative polyA XR_005502514.1 0.35 0.14 6.0e-08 0.26 0.26 0.3 0.28 6.5e-07 5.5e-07 7.6e-08 2.0e-07
16 IL isoform ratio XR_005502515.1 0.26 0.12 3.5e-07 0.34 0.25 0.28 0.33 5.4e-09 1.2e-06 2.5e-07 1.2e-08
17 IL alternative polyA XR_005502515.1 0.24 0.11 5.8e-07 0.29 0.25 0.27 0.26 1.1e-07 1.1e-06 2.8e-07 4.5e-07
18 IL isoform ratio XR_005502514.1 0.26 0.12 4.0e-07 0.34 0.24 0.28 0.32 5.5e-09 1.4e-06 2.3e-07 1.4e-08
19 OFC intron excision ratio chr3_130525654_130567132 0.13 0.09 3.1e-03 0.14 0.12 0.14 0.12 3.6e-04 9.8e-04 2.9e-04 8.6e-04
20 OFC intron excision ratio chr3_130529471_130567132 0.14 0.09 2.3e-03 0.15 0.12 0.15 0.13 2.5e-04 7.1e-04 2.4e-04 6.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.20.30.7-0.5-0.5-0.5-0.5-0.8-0.5-0.50.50.50.70.5-0.20.2-0.8-0.20.70.7-0.7-0.30.3
Area under the delay curve0.20.31.8-0.3-0.0-0.0-0.3-0.10.00.1-0.1-0.1-0.5-0.10.0-0.60.40.7-0.2-0.20.21.4-1.4
BMI with tail13.142.445.66.66.76.76.76.76.66.7-6.6-6.6-6.4-6.46.4-6.76.36.6-6.5-6.56.55.9-5.9
BMI without tail10.321.325.95.04.94.94.84.84.54.6-4.8-4.8-5.0-5.14.3-4.34.84.3-4.6-4.64.63.7-3.6
Body weight14.962.369.58.38.38.38.38.38.18.1-8.2-8.2-7.9-8.18.0-7.97.57.8-7.6-7.67.66.8-6.7
Weight adjusted by age0.80.91.71.01.11.10.81.00.90.9-0.9-0.9-0.9-0.90.8-1.01.01.0-1.3-1.31.30.3-0.3
Bone surface0.00.00.20.40.20.20.1-0.10.10.1-0.1-0.1-0.0-0.20.1-0.30.20.2-0.3-0.30.3-0.10.1
Bone volume0.00.10.20.1-0.2-0.2-0.2-0.5-0.2-0.20.20.20.20.1-0.10.2-0.3-0.20.20.2-0.2-0.40.4
Breakpoint value in progressive ratio session0.30.40.80.70.50.50.60.80.70.8-0.6-0.6-0.5-0.90.4-0.60.60.6-0.5-0.50.50.3-0.3
Number of licking bursts0.00.00.3-0.3-0.1-0.1-0.1-0.0-0.1-0.10.10.10.5-0.00.0-0.0-0.50.00.20.2-0.20.2-0.3
Context. condit. distance diff. score0.20.30.6-0.3-0.5-0.5-0.5-0.5-0.5-0.50.50.50.50.8-0.40.4-0.4-0.40.60.6-0.6-0.40.4
Locomotion velocity, session 12.62.84.8-1.3-1.6-1.6-1.6-1.5-1.8-1.81.81.81.71.1-2.22.1-1.2-2.11.31.3-1.3-1.81.8
Locomotion distance, session 16.07.78.9-2.9-2.9-2.9-3.0-2.7-3.0-3.03.03.03.02.8-3.02.6-2.5-2.62.52.5-2.5-2.72.7
Locomotion velocity, session 22.93.44.4-1.9-2.0-2.0-1.9-1.9-2.0-2.02.12.12.01.7-2.11.5-1.6-1.51.71.7-1.7-1.71.7
Locomotion distance, session 27.510.513.4-3.1-3.4-3.4-3.4-3.2-3.4-3.43.43.42.92.9-3.73.2-2.9-3.13.03.0-3.0-3.43.4
Locomotion velocity, session 34.45.16.6-2.4-2.3-2.3-2.3-2.2-2.3-2.32.32.32.62.4-2.31.9-2.2-1.92.32.3-2.3-2.22.1
Locomotion distance, session 31.41.52.0-1.4-1.3-1.3-1.4-1.2-1.3-1.31.31.31.31.4-1.20.9-1.2-0.91.31.3-1.3-1.01.0
Stereotopy head waving bouts, day 30.00.00.10.20.20.20.20.30.20.2-0.3-0.3-0.1-0.30.40.1-0.3-0.10.10.1-0.1-0.20.2
Stereotopy head waving duration, day 30.00.00.10.30.20.20.20.20.20.2-0.3-0.3-0.2-0.40.20.1-0.0-0.1-0.1-0.10.1-0.10.1
Locomotion velocity, session 72.62.93.7-1.3-1.7-1.7-1.6-1.8-1.8-1.81.71.71.31.4-1.71.8-1.7-1.81.91.9-1.9-1.71.7
Locomotion distance, session 71.62.02.8-0.9-1.4-1.4-1.4-1.5-1.4-1.41.41.40.81.1-1.61.7-1.3-1.71.61.6-1.6-1.41.5
Stereotopy head waving bouts, day 70.40.50.70.80.70.70.70.60.80.8-0.8-0.8-0.8-0.50.7-0.60.80.6-0.6-0.60.60.6-0.6
Stereotopy head waving duration, day 70.00.00.10.00.10.10.1-0.10.20.2-0.1-0.10.0-0.00.3-0.2-0.10.20.30.3-0.30.2-0.2
Locomotion velocity, session 82.02.43.5-1.3-1.5-1.5-1.5-1.6-1.6-1.61.61.61.71.6-1.71.4-1.3-1.41.41.4-1.4-1.91.8
Locomotion distance, session 85.98.610.1-2.7-3.0-3.0-3.1-2.9-3.1-3.13.13.12.83.2-3.22.6-2.6-2.62.82.8-2.8-3.03.1
Degree of sensitization distance0.10.10.60.80.20.20.20.10.10.1-0.1-0.1-0.6-0.7-0.20.50.1-0.50.10.1-0.1-0.20.2
Degree of sensitization stereotypy0.60.71.00.90.80.80.80.70.90.9-0.8-0.8-0.8-0.60.8-1.01.00.9-0.7-0.70.70.9-0.9
Conditioned locomotion0.50.63.5-0.2-0.5-0.5-0.4-0.7-0.5-0.50.40.4-0.2-0.2-0.51.9-0.8-1.90.80.8-0.8-0.60.6
Cocaine response after cond. corrected2.73.15.8-1.6-1.8-1.8-1.7-1.7-1.7-1.71.71.71.21.7-1.62.4-1.7-2.41.61.6-1.6-1.81.8
Cocaine response after cond. not corrected3.84.27.1-1.9-2.0-2.0-2.0-2.0-2.0-2.12.02.01.52.0-1.72.6-2.3-2.72.02.0-2.0-2.02.0
Cocaine response before conditioning0.10.10.4-0.3-0.1-0.1-0.2-0.2-0.3-0.20.20.20.30.40.10.0-0.7-0.00.50.5-0.5-0.0-0.0
Saline control response0.10.10.80.90.20.20.30.10.20.3-0.3-0.3-0.9-0.20.20.10.2-0.1-0.3-0.30.3-0.30.4
Bone: connectivity density0.61.01.6-1.1-1.0-1.0-1.0-1.3-0.9-0.91.01.01.31.0-0.70.5-1.2-0.61.11.1-1.1-0.70.7
Bone: cortical apparent density0.10.10.4-0.4-0.0-0.0-0.00.1-0.0-0.00.00.00.10.30.3-0.3-0.20.2-0.0-0.00.00.6-0.6
Bone: cortical area0.71.02.20.91.01.01.11.01.11.1-1.1-1.1-0.8-0.71.5-1.40.51.3-0.8-0.80.81.1-1.1
Bone: cortical porosity1.01.11.70.71.01.01.01.21.01.0-1.0-1.0-0.7-0.91.1-1.20.91.1-1.3-1.31.30.9-0.9
Bone: cortical porosity1.31.52.10.91.21.21.21.51.21.2-1.2-1.2-1.1-1.21.2-1.21.11.1-1.4-1.41.41.1-1.1
Bone: cortical thickness0.71.23.70.41.01.01.01.01.11.1-1.0-1.0-0.7-0.41.9-1.60.21.5-0.7-0.70.71.6-1.6
Bone: cortical thickness0.20.21.3-0.7-0.3-0.3-0.2-0.4-0.2-0.20.20.21.10.2-0.1-0.3-0.60.30.50.5-0.5-0.20.1
Bone: cortical tissue density0.00.00.3-0.4-0.1-0.1-0.10.1-0.1-0.10.10.10.10.30.2-0.2-0.20.2-0.0-0.00.00.5-0.5
Condit. Reinf. active minus inactive responses0.10.10.40.10.30.30.30.40.40.4-0.4-0.4-0.6-0.30.6-0.1-0.00.1-0.3-0.30.30.6-0.5
Condit. Reinf. active-inactive response ratio0.10.10.40.10.30.30.30.30.30.3-0.3-0.3-0.6-0.30.60.1-0.0-0.1-0.2-0.20.20.5-0.4
Condit. Reinf. active responses0.00.00.1-0.10.00.00.00.20.00.0-0.0-0.0-0.3-0.10.20.3-0.1-0.3-0.3-0.30.30.4-0.3
Condit. Reinf. inactive responses0.10.10.30.1-0.2-0.2-0.10.1-0.4-0.40.30.30.1-0.0-0.50.30.2-0.3-0.3-0.30.3-0.30.3
Incentive salience index mean0.10.10.2-0.5-0.1-0.1-0.2-0.1-0.2-0.20.20.20.10.20.10.5-0.4-0.50.00.0-0.00.4-0.4
Condit. Reinf. lever presses0.10.10.7-0.30.10.10.10.2-0.0-0.0-0.1-0.10.10.20.2-0.00.20.0-0.3-0.30.30.8-0.8
Condit. Reinf. active minus inactive responses0.10.21.10.80.20.20.30.30.30.3-0.3-0.3-1.0-0.6-0.00.60.1-0.60.20.2-0.20.1-0.0
Condit. Reinf. active-inactive response ratio0.20.20.70.80.40.40.40.50.40.4-0.4-0.4-0.9-0.70.10.30.4-0.3-0.2-0.20.20.3-0.3
Condit. Reinf. active responses0.20.31.20.90.50.50.50.50.50.5-0.5-0.5-1.1-0.70.3-0.10.40.1-0.0-0.00.00.7-0.6
Condit. Reinf. inactive responses0.30.41.20.50.60.60.60.60.60.6-0.6-0.6-0.5-0.40.8-1.10.41.1-0.4-0.40.40.9-0.9
Condit. Reinf. lever presses1.21.63.41.91.41.41.41.51.41.4-1.4-1.4-1.4-1.50.9-1.11.41.1-0.8-0.80.81.0-1.0
Condit. Reinf. lever reinforcers received0.30.41.61.00.50.50.60.60.50.5-0.6-0.6-1.2-0.80.4-0.20.40.2-0.2-0.20.20.7-0.7
Conditioned reinforcement - actives2.42.45.0-1.4-1.4-1.4-1.5-1.3-1.4-1.41.41.42.21.5-1.81.3-1.6-1.41.11.1-1.1-2.22.1
Conditioned reinforcement - inactives1.92.15.2-1.5-1.3-1.3-1.4-1.3-1.2-1.21.11.12.31.4-1.51.4-1.6-1.51.01.0-1.0-2.12.1
Conditioned locomotion3.13.74.7-2.0-2.0-2.0-2.1-2.0-2.2-2.22.12.12.12.0-2.01.7-2.0-1.71.71.7-1.7-1.61.6
Patch foraging indifference point 0 sec0.50.73.3-0.4-1.0-1.0-0.6-0.5-0.8-0.90.70.70.71.1-0.90.5-0.5-0.5-0.0-0.00.0-1.81.8
Patch foraging indifference point AUC1.51.82.4-1.5-1.4-1.4-1.4-1.3-1.3-1.31.41.41.21.0-1.41.1-1.3-1.11.51.5-1.5-0.90.9
Delay disc. indifference point, 0s delay1.01.13.40.70.80.80.60.60.80.8-0.9-0.9-1.3-1.10.7-1.21.21.2-0.9-0.90.91.8-1.8
Delay disc. indifference point, 16s delay0.70.71.5-1.2-1.0-1.0-1.1-1.0-1.0-1.01.01.00.60.9-0.80.4-0.8-0.40.80.8-0.80.1-0.1
Delay disc. indifference point, 2s delay1.31.53.41.01.01.00.71.01.01.0-1.0-1.0-1.4-1.20.8-1.21.51.2-1.3-1.31.31.9-1.9
Delay disc. indifference point, 24s delay1.21.12.3-1.5-1.4-1.4-1.3-1.3-1.2-1.11.21.20.81.1-1.01.0-1.0-0.90.90.9-0.9-0.10.1
Delay disc. indifference point, 4s delay1.51.63.01.01.01.00.90.91.11.0-1.2-1.2-1.2-1.10.9-1.61.41.7-1.2-1.21.21.7-1.7
Delay disc. indifference point, 8s delay0.30.30.7-0.8-0.6-0.6-0.8-0.6-0.6-0.50.50.50.10.6-0.60.3-0.3-0.20.60.6-0.60.5-0.5
Indifference point function ln k0.30.51.10.80.50.50.70.60.70.7-0.8-0.80.0-0.50.4-0.80.60.8-1.0-1.01.0-0.10.1
Indifference point function log k0.30.51.10.80.50.50.70.60.70.7-0.8-0.80.0-0.50.4-0.80.60.8-1.0-1.01.0-0.10.1
Patch foraging total patch changes 0 sec0.81.24.0-0.7-1.3-1.3-0.9-0.8-1.1-1.21.01.01.01.3-1.30.8-0.8-0.80.30.3-0.3-2.02.0
Patch foraging total patch changes 12 sec0.10.10.20.3-0.1-0.10.10.30.20.1-0.1-0.1-0.4-0.20.1-0.40.30.5-0.3-0.30.3-0.20.3
Patch foraging total patch changes 18 sec2.43.14.0-1.6-2.0-2.0-1.7-2.0-1.7-1.71.71.71.21.8-1.71.9-1.7-1.91.81.8-1.8-1.71.8
Patch foraging total patch changes 24 sec0.91.11.8-0.9-1.2-1.2-0.9-1.2-1.1-1.11.01.00.40.9-1.21.3-0.9-1.31.11.1-1.1-1.01.1
Patch foraging total patch changes 6 sec0.30.40.9-0.6-0.9-0.9-0.6-0.5-0.6-0.70.60.60.40.9-0.60.2-0.7-0.20.60.6-0.6-0.90.9
Patch foraging time to switch 0 sec2.23.55.41.81.91.91.91.82.02.0-1.9-1.9-2.3-1.52.3-1.61.71.6-1.7-1.71.71.9-1.8
Patch foraging water rate 0 sec2.33.75.7-2.1-2.1-2.1-2.0-2.0-2.1-2.12.02.02.21.7-2.41.4-1.7-1.41.81.8-1.8-1.81.7
Patch foraging water rate 12 sec2.84.37.4-2.4-2.1-2.1-2.1-2.1-2.2-2.22.12.12.22.7-2.01.7-2.2-1.62.22.2-2.2-1.51.4
Patch foraging water rate 18 sec5.87.89.5-3.0-2.8-2.8-2.7-2.9-2.8-2.72.82.83.12.9-2.82.5-2.9-2.52.62.6-2.6-3.03.0
Patch foraging water rate 24 sec3.85.36.6-2.3-2.2-2.2-2.3-2.4-2.4-2.32.32.32.52.0-2.62.2-2.2-2.22.32.3-2.3-2.32.2
Patch foraging water rate 6 sec2.63.86.0-2.1-1.6-1.6-1.7-2.0-1.9-1.91.81.81.71.7-1.72.1-2.3-2.12.52.5-2.5-1.51.5
Seeking ratio, delayed vs. immediate footshock0.40.40.90.90.80.80.70.70.60.6-0.7-0.7-0.5-0.90.3-0.70.60.6-0.6-0.60.60.3-0.3
Distance traveled before self-admin0.50.51.10.50.70.70.80.40.60.7-0.7-0.7-0.9-1.00.5-0.41.10.4-0.7-0.70.70.6-0.6
Distance traveled after self-admin0.40.40.9-0.8-0.6-0.6-0.6-1.0-0.7-0.50.70.7-0.10.6-0.20.8-0.5-0.80.90.9-0.90.4-0.4
Extensor digitorum longus weight0.51.94.11.51.51.51.41.61.41.4-1.4-1.4-1.1-1.70.9-2.01.52.0-0.9-0.90.90.8-0.8
Bone: elastic displacement0.20.30.70.40.50.50.50.60.50.5-0.5-0.5-0.3-0.60.4-0.80.30.8-0.1-0.10.10.6-0.6
Bone: elastic work3.74.87.82.02.22.22.22.22.22.2-2.2-2.2-2.0-1.92.2-2.82.02.8-1.9-1.91.92.3-2.3
Bone: endosteal estimation1.63.46.72.61.81.81.81.81.81.8-1.8-1.8-1.9-2.21.1-1.72.21.7-2.1-2.12.10.8-0.7
Bone: endosteal perimeter0.10.21.01.00.40.40.40.40.40.4-0.4-0.4-0.8-0.60.1-0.10.60.1-0.4-0.40.4-0.30.3
Epididymis fat weight12.228.432.35.45.75.75.55.55.25.3-5.4-5.4-5.1-5.35.3-5.55.25.4-5.4-5.45.44.6-4.6
Delta time in closed arm before/after self-admin0.70.61.2-0.4-0.7-0.7-0.6-0.8-0.7-0.70.70.71.11.1-0.70.5-1.0-0.61.11.1-1.1-0.70.6
Delta time in open arm before/after self-admin1.51.52.11.11.31.31.31.21.41.2-1.3-1.3-1.3-1.41.3-1.01.11.0-1.1-1.11.11.1-1.1
Diff in mean of infusions in LGA sessions0.00.00.1-0.1-0.1-0.1-0.10.30.00.20.10.10.00.2-0.1-0.20.20.2-0.1-0.10.10.1-0.1
Delay discount exponential model param0.20.21.40.40.20.20.40.20.10.1-0.1-0.10.3-0.10.10.4-0.2-0.50.10.1-0.1-1.21.2
Extinction: sum of active levers before priming0.10.10.20.30.20.20.30.30.20.3-0.2-0.2-0.1-0.00.0-0.50.30.4-0.3-0.30.3-0.50.5
Active lever presses in extinction session 60.50.51.00.90.90.90.80.80.91.0-0.8-0.8-0.3-0.70.6-0.60.60.6-0.7-0.70.7-0.20.2
Bone: final force1.01.72.11.41.31.31.31.21.31.3-1.3-1.3-1.3-1.41.4-1.21.11.1-1.2-1.21.21.3-1.3
Bone: final moment0.91.51.81.31.31.31.31.21.21.2-1.3-1.3-1.2-1.21.3-1.21.01.2-1.1-1.11.11.1-1.1
Food consumed during 24 hour testing period0.20.20.70.60.50.50.50.60.50.5-0.5-0.5-0.4-0.30.6-0.80.10.8-0.3-0.30.30.3-0.3
Glucose1.82.74.32.11.81.81.81.81.71.7-1.8-1.8-2.0-1.91.5-1.51.61.5-1.2-1.21.21.3-1.2
Heart weight1.82.55.51.81.51.51.71.71.51.5-1.6-1.6-2.4-1.31.9-1.41.71.4-1.6-1.61.61.0-0.9
Delay discount hyperbolic model param0.30.31.90.1-0.1-0.10.1-0.0-0.1-0.20.20.20.50.2-0.10.7-0.5-0.70.30.3-0.3-1.41.4
Intermittent access intake day 1-15 change0.10.10.40.40.30.30.20.30.30.3-0.2-0.20.10.0-0.1-0.60.40.6-0.5-0.50.5-0.50.5
Intermittent access intake escalation0.10.10.30.30.20.20.20.20.20.2-0.1-0.10.00.0-0.2-0.60.30.6-0.4-0.40.4-0.50.5
Intermittent access intake escalation 21.51.52.81.11.31.31.21.31.21.2-1.2-1.2-0.9-0.90.9-1.71.41.7-1.5-1.51.50.2-0.2
Intermitt. access day 1 inactive lever presses0.50.50.80.60.90.90.70.70.90.9-0.9-0.9-0.3-0.40.9-0.90.40.8-0.7-0.70.70.4-0.4
Intermitt. access day 15 inactive lever presses1.21.32.11.21.41.41.31.41.41.4-1.4-1.4-0.1-0.41.1-1.30.61.2-1.2-1.21.2-0.10.1
Intermitt. access escalation Index0.90.81.51.20.80.81.01.01.11.1-1.0-1.0-0.6-0.71.1-1.00.50.9-0.8-0.80.80.6-0.5
Intermittent access day 1 total infusions0.10.10.30.40.20.20.20.40.30.3-0.3-0.30.1-0.30.2-0.1-0.00.1-0.5-0.50.5-0.20.2
Intermittent access day 15 total infusions0.10.10.50.50.20.20.20.30.20.2-0.2-0.20.4-0.1-0.0-0.4-0.00.4-0.5-0.50.5-0.70.7
Intermittent access terminal intake (last 3 days)0.30.30.60.70.50.50.50.60.60.6-0.6-0.6-0.0-0.50.4-0.60.30.6-0.8-0.80.8-0.40.4
Intermittent access total infusions0.10.20.30.50.30.30.30.50.40.4-0.4-0.40.2-0.40.2-0.40.00.4-0.6-0.60.6-0.40.4
Intermittent access day 1 locomotion0.10.10.2-0.1-0.2-0.2-0.4-0.2-0.4-0.40.30.30.5-0.0-0.30.1-0.3-0.1-0.1-0.10.1-0.20.1
Intermittent access day 15 total locomotion0.20.21.0-0.4-0.3-0.3-0.4-0.3-0.4-0.40.40.41.00.5-0.20.2-0.8-0.20.00.0-0.0-0.80.7
Intermittent access total locomotion0.70.81.6-0.9-0.9-0.9-1.0-0.8-1.0-1.01.01.01.30.8-0.90.6-1.1-0.60.60.6-0.6-0.90.8
Intermittent access standard deviation0.20.20.9-0.3-0.4-0.4-0.3-0.3-0.3-0.30.40.40.30.1-0.8-0.00.10.1-0.0-0.00.0-0.91.0
Left kidney weight1.85.28.22.52.42.42.42.42.32.3-2.3-2.3-2.9-2.82.3-1.72.31.7-2.0-2.02.02.0-2.0
Right kidney weight1.33.77.42.22.02.01.92.21.81.8-1.9-1.9-2.7-2.42.0-1.51.91.5-1.8-1.81.81.7-1.6
Cocaine induced anxiety0.30.30.9-0.5-0.6-0.6-0.5-0.7-0.5-0.50.50.50.40.5-0.90.2-0.1-0.20.60.6-0.6-0.40.5
Post-drug Anxiety1.61.82.81.71.21.21.31.21.31.3-1.3-1.3-0.9-1.20.7-1.61.61.6-1.5-1.51.51.0-1.0
Baseline Anxiety5.76.17.82.62.52.52.72.62.72.7-2.7-2.7-2.0-2.52.4-2.12.22.1-2.8-2.82.81.8-1.8
Tail length0.41.43.41.51.51.51.31.31.21.2-1.3-1.3-1.4-1.81.2-0.61.10.6-0.9-0.90.90.2-0.2
Length with tail2.28.210.93.23.23.23.23.13.23.2-3.2-3.2-3.0-3.23.3-2.42.52.4-2.4-2.42.42.0-1.9
Length without tail2.35.17.72.12.22.22.42.42.62.6-2.5-2.5-1.8-1.92.8-2.41.72.3-2.1-2.12.12.0-2.0
Times rat made contact with spout0.80.91.91.41.01.01.01.01.01.0-1.0-1.0-1.0-1.40.4-1.01.21.0-0.7-0.70.70.5-0.5
Lifetime Intake0.10.10.6-0.1-0.3-0.3-0.3-0.2-0.2-0.20.20.20.70.2-0.30.2-0.5-0.2-0.0-0.00.0-0.80.7
Liver weight, left0.20.40.80.70.70.70.70.50.70.8-0.7-0.7-0.6-0.90.8-0.10.20.10.10.1-0.10.7-0.7
Liver weight, right0.40.61.90.81.01.00.80.90.90.8-0.8-0.8-0.8-1.41.0-0.10.40.1-0.4-0.40.40.6-0.6
Locomotor activity0.30.51.00.90.90.90.70.80.60.7-0.7-0.7-0.7-0.90.4-0.51.00.5-0.6-0.60.60.4-0.4
Locomotor testing distance0.20.30.6-0.5-0.2-0.2-0.7-0.6-0.7-0.60.60.60.40.3-0.80.8-0.1-0.70.50.5-0.5-0.40.4
Locomotor testing rearing0.20.30.9-0.5-0.3-0.3-0.4-0.5-0.5-0.40.40.40.40.2-0.30.6-0.3-0.60.90.9-0.9-0.30.3
Locomotion in novel chamber0.40.51.3-0.6-0.7-0.7-0.5-0.3-0.5-0.60.50.51.20.6-0.40.6-0.9-0.70.30.3-0.3-1.11.1
Locomotion in novel chamber post-restriction2.32.84.6-1.7-1.6-1.6-1.6-1.8-1.6-1.61.61.61.91.6-1.11.6-2.2-1.61.91.9-1.9-1.21.2
Fecal boli incidents, locomotor time 10.70.82.2-0.5-0.7-0.7-0.9-0.9-1.1-1.11.11.10.70.4-1.50.8-0.4-0.80.80.8-0.8-1.11.1
Change in fecal boli incidents, locomotor task0.10.10.6-0.2-0.1-0.10.2-0.00.20.2-0.2-0.20.40.30.7-0.1-0.60.00.10.1-0.10.0-0.0
Time >=10cm from walls, locomotor time 10.20.20.7-0.4-0.4-0.4-0.2-0.5-0.3-0.30.30.30.20.1-0.10.8-0.5-0.80.50.5-0.5-0.30.3
Bouts of movement, locomotor time 11.21.32.0-1.2-1.4-1.4-1.1-1.3-1.1-1.01.11.10.90.4-1.41.2-0.9-1.21.21.2-1.2-1.21.2
Total resting periods, locomotor time 11.71.92.7-1.4-1.6-1.6-1.3-1.5-1.3-1.21.31.31.20.8-1.51.4-1.2-1.41.41.4-1.4-1.51.6
Rest time, locomotor task time 11.11.22.6-0.7-1.3-1.3-0.6-1.5-0.8-0.80.80.80.60.1-1.01.0-0.8-1.01.41.4-1.4-1.51.6
Distance moved, locomotor task time 10.20.21.1-0.70.00.0-0.50.1-0.5-0.40.50.50.51.00.10.1-0.4-0.2-0.0-0.00.00.6-0.7
Vertical activity count, locomotor time 10.80.91.80.60.90.90.81.20.80.8-0.8-0.8-0.5-0.01.3-1.10.61.0-0.9-0.90.91.3-1.3
Time >=10cm from walls, locomotor time 21.92.02.81.51.31.31.61.31.51.4-1.5-1.5-1.5-1.51.7-1.31.21.2-1.3-1.31.31.3-1.2
Bouts of movement, locomotor time 20.10.11.40.40.10.10.40.10.10.1-0.1-0.1-0.5-1.2-0.20.20.7-0.2-0.2-0.20.20.3-0.3
Total resting periods, locomotor time 20.20.21.40.50.30.30.60.30.30.2-0.3-0.3-0.6-1.20.0-0.00.90.1-0.4-0.40.40.4-0.4
Rest time, locomotor task time 20.10.10.30.20.00.00.2-0.30.10.2-0.1-0.1-0.1-0.5-0.3-0.10.50.10.00.0-0.0-0.40.5
Distance moved, locomotor task time 20.80.91.5-1.2-0.9-0.9-1.1-0.7-1.0-1.11.01.00.71.0-0.61.1-1.2-1.11.01.0-1.0-0.10.1
Vertical activity count, locomotor time 20.10.20.3-0.4-0.4-0.4-0.5-0.2-0.5-0.50.50.5-0.10.2-0.10.5-0.5-0.50.40.4-0.40.3-0.3
Light reinforcement 10.50.82.0-0.7-0.9-0.9-0.9-0.8-0.8-0.81.01.01.00.8-1.00.8-0.7-0.70.70.7-0.7-1.41.4
Light reinforcement 20.30.51.7-0.5-0.3-0.3-0.7-0.4-0.6-0.50.70.71.30.8-0.9-0.1-0.40.10.30.3-0.3-1.31.2
Bone: marrow area1.53.26.52.61.71.71.81.71.81.8-1.7-1.7-1.9-2.11.0-1.62.11.6-2.0-2.02.00.7-0.7
Bone: maximum diameter0.30.61.31.10.80.80.80.80.80.8-0.8-0.8-0.6-1.00.6-0.90.80.9-0.7-0.70.70.2-0.1
Bone: maximum force0.91.52.31.31.31.31.31.21.31.3-1.3-1.3-1.3-1.11.5-1.21.01.1-1.1-1.11.11.2-1.2
Bone: maximum moment0.91.62.31.31.31.31.31.31.31.3-1.3-1.3-1.2-1.11.5-1.31.01.3-1.1-1.11.11.2-1.2
Mean time between licks in bursts0.30.41.4-0.7-0.5-0.5-0.5-0.6-0.4-0.50.50.50.60.70.20.2-1.2-0.20.90.9-0.9-0.30.3
Mean num. licks in bursts0.30.41.21.10.60.60.60.50.60.6-0.6-0.6-1.0-0.80.2-0.41.00.4-0.6-0.60.6-0.00.1
Cd content in liver0.50.51.00.70.70.70.70.70.70.7-0.7-0.7-0.5-1.01.0-0.80.30.7-0.4-0.40.40.8-0.8
Co content in liver0.80.92.1-1.2-0.9-0.9-0.9-0.8-0.8-0.80.80.81.50.9-0.30.7-1.4-0.81.11.1-1.1-0.60.5
Cu content in liver0.40.51.1-0.6-0.7-0.7-0.5-0.7-0.5-0.50.50.50.60.4-0.60.9-0.8-0.91.01.0-1.0-0.70.7
Fe content in liver0.50.62.20.80.90.90.80.70.80.8-0.8-0.8-1.5-0.71.2-0.20.30.20.10.1-0.10.9-0.9
K content in liver0.40.41.3-1.2-0.6-0.6-0.5-0.5-0.5-0.50.50.51.01.0-0.30.3-0.5-0.30.80.8-0.80.3-0.3
Mg content in liver0.10.10.8-0.30.10.10.20.20.20.2-0.2-0.2-0.00.50.6-0.20.10.20.00.0-0.00.9-0.9
Mn content in liver2.63.04.1-1.5-1.8-1.8-1.7-1.6-1.8-1.81.71.71.51.7-1.82.0-1.8-2.01.61.6-1.6-1.71.7
Na content in liver0.10.10.7-0.40.10.10.00.10.10.1-0.0-0.00.30.30.3-0.0-0.10.00.20.2-0.20.8-0.9
Rb content in liver1.01.32.70.61.01.01.10.91.11.1-1.1-1.1-0.9-0.91.3-1.31.01.2-1.0-1.01.01.6-1.6
Se content in liver0.81.01.90.51.11.11.21.21.21.2-1.2-1.2-0.7-1.11.4-0.90.60.8-0.6-0.60.61.2-1.3
Sr content in liver1.71.52.6-0.9-1.2-1.2-1.3-0.8-1.3-1.31.31.31.20.9-1.31.6-1.2-1.61.31.3-1.3-1.21.2
Zn content in liver0.20.20.7-0.6-0.2-0.2-0.1-0.1-0.1-0.10.20.20.50.30.40.4-0.8-0.50.90.9-0.90.1-0.1
Bone: minimum diameter0.61.21.71.31.11.11.11.21.21.2-1.1-1.1-1.1-0.91.2-1.20.81.2-1.0-1.01.00.9-0.9
Time in familiar zone, hab. session 10.30.20.80.20.40.40.40.20.60.6-0.5-0.50.2-0.20.7-0.90.10.9-0.0-0.00.00.6-0.6
Time in novel zone, hab. session 10.10.10.40.50.30.30.30.50.10.1-0.2-0.2-0.5-0.4-0.10.10.5-0.1-0.6-0.60.60.0-0.0
Total zone transitions, hab. session 11.42.03.0-1.4-1.4-1.4-1.5-1.3-1.5-1.41.51.51.51.1-1.50.6-1.5-0.61.71.7-1.7-1.31.3
Total locomotion distance, hab. session 11.82.53.0-1.6-1.6-1.6-1.6-1.7-1.6-1.61.61.61.51.3-1.71.3-1.7-1.31.71.7-1.7-1.51.5
Locomotion velocity, hab. session 12.63.74.8-2.0-2.0-2.0-2.0-2.0-2.0-2.01.91.91.71.7-1.91.6-2.0-1.52.22.2-2.2-1.71.7
Time in familiar zone, hab. session 20.60.60.8-0.8-0.7-0.7-0.9-0.8-0.8-0.80.80.80.90.6-0.80.9-0.6-0.80.60.6-0.6-0.90.9
Time in novel zone, hab. session 21.31.31.81.31.11.11.31.21.21.2-1.3-1.3-1.3-1.11.1-0.91.10.9-0.9-0.90.91.1-1.0
Total zone transitions, hab. session 20.30.40.9-0.4-0.7-0.7-0.9-0.5-0.7-0.70.80.80.60.6-0.90.3-0.5-0.30.40.4-0.4-0.91.0
Total locomotion distance, hab. session 21.82.44.0-1.2-1.6-1.6-1.7-1.5-1.6-1.61.61.61.21.2-2.01.7-1.3-1.61.31.3-1.3-1.92.0
Locomotion velocity, hab. session 22.93.95.5-1.7-2.0-2.0-2.1-1.9-2.0-2.02.02.01.71.6-2.42.0-1.8-1.91.71.7-1.7-2.22.2
Novel to familiar place preference ratio0.00.00.20.20.10.10.2-0.00.10.1-0.2-0.2-0.10.00.10.40.0-0.4-0.1-0.10.10.2-0.2
Novelty place preference0.10.10.10.20.20.20.40.10.20.2-0.3-0.3-0.1-0.00.30.30.0-0.3-0.2-0.20.20.3-0.3
Time in novel zone, NPP test0.20.20.50.60.50.50.70.40.60.6-0.6-0.6-0.4-0.40.60.00.4-0.1-0.4-0.40.40.5-0.5
Total zone transitions, NPP test1.31.82.5-1.3-1.5-1.5-1.6-1.4-1.5-1.51.51.51.21.5-1.50.8-1.2-0.81.31.3-1.3-1.21.2
Total locomotion distance, NPP test3.44.66.5-1.9-2.3-2.3-2.3-2.2-2.3-2.32.32.31.82.2-2.62.1-1.9-2.11.81.8-1.8-2.22.2
Locomotion velocity, NPP test4.25.97.5-2.2-2.6-2.6-2.6-2.5-2.6-2.62.62.62.12.5-2.72.4-2.2-2.32.02.0-2.0-2.42.4
Intraocular pressure0.30.40.9-0.2-0.5-0.5-0.7-0.4-0.9-0.90.70.70.50.7-0.80.7-0.7-0.70.20.2-0.2-1.01.0
Delta distance traveled before/after self-admin0.70.81.9-1.1-0.8-0.8-0.9-1.0-0.9-0.80.90.90.31.4-0.30.7-1.1-0.71.11.1-1.10.5-0.5
Delta ambulatory time before/after self-admin0.70.81.8-1.0-0.8-0.8-0.9-1.0-0.8-0.80.90.90.51.4-0.40.7-1.1-0.71.21.2-1.20.1-0.1
Parametrial fat weight18.736.442.46.56.56.56.56.26.36.2-6.4-6.4-5.8-6.15.9-5.76.05.6-5.8-5.85.85.3-5.3
Pavlov. Cond. lever latency0.30.31.21.10.60.60.60.40.60.5-0.4-0.4-1.0-0.60.3-0.50.50.5-0.4-0.40.4-0.40.5
Pavlov. Cond. magazine entry latency1.62.14.00.91.41.41.41.51.31.3-1.4-1.4-1.1-1.31.4-1.41.41.4-1.5-1.51.52.0-2.0
Pavlov. Cond. change in total contacts0.20.21.3-0.70.10.10.10.2-0.0-0.0-0.1-0.10.20.30.4-0.1-0.10.1-0.1-0.10.11.1-1.1
Pavlov. Cond. index score0.40.52.5-0.20.50.50.50.70.40.4-0.6-0.6-0.1-0.20.8-0.60.50.6-0.7-0.70.71.5-1.6
Pavlov. Cond. latency score0.10.21.2-0.7-0.0-0.0-0.10.1-0.1-0.1-0.1-0.10.50.30.3-0.1-0.10.1-0.2-0.20.21.0-1.1
Pavlov. Cond. lever contacts0.10.10.8-0.4-0.0-0.0-0.00.1-0.1-0.1-0.1-0.10.3-0.00.10.20.1-0.2-0.2-0.20.20.8-0.9
Pavlov. Cond. magazine entry number2.43.05.0-1.2-1.7-1.7-1.6-1.9-1.5-1.61.71.71.51.6-1.71.7-1.7-1.71.81.8-1.8-2.22.2
Pavlov. Cond. intertrial magazine entries3.03.66.3-1.2-1.8-1.8-1.7-1.7-1.8-1.81.71.71.01.6-1.92.5-1.8-2.51.91.9-1.9-2.32.4
Pavlov. Cond. lever-magazine prob. diff.0.60.73.0-0.00.70.70.60.80.50.5-0.7-0.7-0.3-0.30.9-0.80.60.7-0.8-0.80.81.7-1.7
Pavlov. Cond. response bias1.41.73.80.71.21.21.21.41.01.0-1.3-1.3-1.0-1.01.4-1.11.21.1-1.4-1.41.41.9-1.9
Pavlov. Cond. lever latency2.93.96.2-2.5-2.0-2.0-2.1-2.2-2.1-2.12.12.12.32.2-1.81.9-1.9-1.91.51.5-1.5-1.81.8
Pavlov. Cond. magazine entry latency0.70.82.31.50.90.90.91.01.00.9-0.9-0.9-1.0-1.30.4-0.81.10.8-0.8-0.80.80.2-0.2
Pavlov. Cond. change in total contacts3.34.56.92.62.12.12.22.22.22.2-2.2-2.2-2.6-2.31.9-1.92.11.9-1.8-1.81.82.0-2.0
Pavlov. Cond. index score3.03.86.32.52.02.02.02.22.12.1-2.0-2.0-2.2-2.21.6-1.92.01.8-1.7-1.71.71.6-1.6
Pavlov. Cond. latency score2.02.54.22.11.61.61.61.81.71.7-1.6-1.6-1.8-1.81.3-1.51.61.5-1.4-1.41.41.3-1.3
Pavlov. Cond. lever contacts2.63.65.42.32.02.02.02.12.02.0-2.0-2.0-2.0-2.01.7-1.81.81.8-1.7-1.71.71.7-1.7
Pavlov. Cond. magazine entry number1.62.04.0-2.0-1.4-1.4-1.4-1.6-1.5-1.51.41.41.61.7-1.01.3-1.5-1.31.31.3-1.3-0.90.9
Pavlov. Cond. intertrial magazine entries0.40.51.1-1.1-0.7-0.7-0.7-0.6-0.8-0.70.70.70.41.0-0.20.7-0.8-0.70.70.7-0.7-0.20.2
Pavlov. Cond. lever-magazine prob. diff.3.74.77.02.62.22.22.22.42.32.3-2.2-2.2-2.3-2.31.9-2.12.12.1-1.9-1.91.91.9-1.9
Pavlov. Cond. response bias2.43.36.02.41.91.91.92.02.01.9-1.9-1.9-2.0-2.11.5-1.71.81.7-1.6-1.61.61.4-1.4
Time in closed arm before self-admin0.10.10.5-0.1-0.4-0.4-0.4-0.1-0.3-0.20.40.40.2-0.3-0.50.2-0.1-0.2-0.2-0.20.2-0.60.7
Time in closed arm after self-admin2.93.04.7-1.2-1.7-1.7-1.7-1.6-1.7-1.61.81.82.21.5-1.81.5-1.9-1.51.51.5-1.5-2.12.1
Time in open arm before self-admin0.20.20.70.00.40.40.50.20.40.3-0.5-0.5-0.6-0.30.7-0.10.20.2-0.2-0.20.20.8-0.8
Time in open arm after self-admin1.92.14.01.01.51.51.51.31.61.4-1.6-1.6-1.9-1.51.7-0.91.30.9-1.0-1.01.02.0-2.0
Bone: periosteal estimation1.42.94.52.11.71.71.71.71.71.7-1.7-1.7-1.7-1.81.4-1.91.71.9-1.8-1.81.81.0-1.0
Bone: periosteal perimeter0.00.10.40.60.20.20.20.20.20.2-0.2-0.2-0.6-0.40.3-0.00.00.00.10.1-0.1-0.10.1
Bone: post-yield work0.30.41.00.70.60.60.60.60.70.7-0.6-0.6-1.0-0.21.0-0.40.40.3-0.8-0.80.80.5-0.4
Progressive ratio test 1 active lever presses0.10.20.5-0.1-0.4-0.4-0.4-0.3-0.4-0.40.40.40.7-0.0-0.50.3-0.4-0.30.10.1-0.1-0.70.7
Progressive ratio test 1 breakpoint0.10.10.20.0-0.2-0.2-0.3-0.2-0.2-0.20.20.20.5-0.2-0.30.1-0.2-0.1-0.1-0.10.1-0.50.4
Progressive ratio test 1 inactive lever presses0.20.20.9-0.1-0.2-0.2-0.4-0.3-0.3-0.30.30.30.90.3-0.7-0.0-0.30.00.20.2-0.2-1.00.9
Progressive ratio test 2 active lever presses0.10.10.4-0.1-0.1-0.1-0.2-0.0-0.2-0.20.20.20.50.2-0.2-0.2-0.20.2-0.2-0.20.2-0.60.6
Progressive ratio test 2 breakpoint0.10.10.20.10.10.10.00.20.00.0-0.1-0.10.3-0.00.0-0.50.10.5-0.4-0.40.4-0.30.3
Progressive ratio test 2 inactive lever presses0.30.40.70.70.70.70.40.70.50.5-0.5-0.50.4-0.20.1-0.80.40.8-0.9-0.90.9-0.80.7
Incentive Sensitization - Responses0.10.10.3-0.2-0.2-0.2-0.20.1-0.2-0.20.20.20.60.5-0.1-0.1-0.40.1-0.0-0.00.0-0.60.5
Incentive Sensitization - Breakpoint0.10.10.4-0.3-0.3-0.3-0.3-0.0-0.3-0.30.20.20.60.6-0.2-0.1-0.40.10.10.1-0.1-0.60.6
Sum of active levers in priming session hrs 5-60.80.81.2-0.9-1.0-1.0-0.9-0.8-0.8-0.70.90.91.11.0-0.90.7-0.9-0.70.90.9-0.9-0.90.9
Progressive ratio2.83.23.9-1.8-2.0-2.0-1.8-1.6-1.8-1.91.81.82.01.7-1.81.8-2.0-1.81.61.6-1.6-1.71.7
Food seeking constrained by brief footshock4.65.77.7-2.8-2.6-2.6-2.5-2.5-2.6-2.72.52.51.82.4-2.32.4-2.1-2.32.52.5-2.5-1.51.5
Seeking ratio, punishment vs. effort0.40.51.30.60.70.70.60.40.60.6-0.6-0.6-1.1-0.60.7-0.61.00.7-0.5-0.50.51.1-1.1
Retroperitoneal fat weight22.674.283.19.18.98.98.98.79.09.1-9.0-9.0-8.7-8.78.5-8.58.58.4-8.2-8.28.27.9-7.8
Reaction time number correct0.20.30.7-0.5-0.2-0.2-0.6-0.5-0.5-0.50.50.50.60.6-0.60.6-0.6-0.60.60.6-0.6-0.80.8
Reaction time mean minus median1.62.13.11.61.61.61.51.51.51.5-1.4-1.4-1.5-1.81.4-1.51.51.4-1.3-1.31.31.1-1.1
Reaction time mean minus median AUC1.21.52.81.51.51.51.31.31.41.3-1.2-1.2-1.0-1.71.1-1.31.21.3-1.0-1.01.00.8-0.8
Reaction time num false alarms2.73.75.2-1.8-2.3-2.3-1.8-1.9-1.8-1.91.71.71.81.8-1.72.1-2.2-2.11.91.9-1.9-1.91.9
Reaction time num false alarms AUC2.33.14.6-1.7-2.1-2.1-1.7-1.7-1.7-1.71.61.61.71.7-1.61.8-2.0-1.91.71.7-1.7-1.61.6
Reaction time trials correct on left0.20.30.7-0.5-0.2-0.2-0.6-0.5-0.5-0.50.50.50.60.6-0.60.6-0.6-0.60.60.6-0.6-0.80.8
Reaction time trials on left0.20.30.6-0.5-0.2-0.2-0.6-0.5-0.5-0.50.50.50.60.6-0.60.6-0.5-0.60.60.6-0.6-0.80.8
Reaction time mean2.83.94.82.22.22.22.02.02.22.1-1.9-1.9-2.0-2.21.6-2.22.12.2-1.6-1.61.61.6-1.6
Reaction time mean AUC2.63.54.52.12.12.11.91.92.02.0-1.8-1.8-1.9-2.11.6-2.12.02.1-1.6-1.61.61.5-1.6
Median of all reaction times2.33.24.12.02.02.01.91.82.01.9-1.8-1.8-1.8-1.91.4-2.02.02.0-1.4-1.41.41.5-1.5
Reaction time omissions0.50.71.61.00.90.90.81.00.90.9-0.7-0.7-0.8-1.30.5-1.10.91.1-0.7-0.70.70.6-0.6
Reaction time false alarm rate1.62.23.9-1.4-2.0-2.0-1.4-1.4-1.4-1.51.41.41.41.3-1.41.5-1.6-1.51.41.4-1.4-1.21.2
Reaction time premature initiation rate0.20.31.5-0.3-0.4-0.4-0.5-0.2-0.6-0.50.50.50.70.3-0.70.4-0.4-0.4-0.0-0.00.0-1.21.2
Reaction time premature initiations0.50.82.7-0.6-0.6-0.6-0.8-0.6-0.9-0.80.80.81.10.7-1.10.7-0.7-0.70.40.4-0.4-1.71.6
Std. dev. reaction times2.23.04.01.91.81.81.81.71.81.8-1.6-1.6-1.9-2.01.5-2.01.92.0-1.5-1.51.51.5-1.5
Reaction time trials completed0.20.30.6-0.5-0.2-0.2-0.6-0.5-0.5-0.50.50.50.60.6-0.60.6-0.5-0.60.60.6-0.6-0.80.8
Reaction time trials AUC0.20.20.6-0.4-0.1-0.1-0.5-0.4-0.4-0.40.40.40.40.5-0.50.5-0.4-0.50.50.5-0.5-0.80.8
Run reversals in cocaine runway, females1.51.42.21.21.01.01.11.31.21.2-1.2-1.2-0.9-1.21.0-1.01.11.0-1.4-1.41.41.5-1.5
Run reversals in cocaine runway, males1.00.92.21.11.01.01.00.80.90.9-1.0-1.0-1.5-1.30.7-0.61.20.6-0.7-0.70.71.2-1.1
Latency to leave start box in cocaine runway0.10.10.20.30.40.40.10.20.20.2-0.2-0.2-0.00.20.4-0.5-0.30.4-0.1-0.10.1-0.30.3
Latency to leave start box in cocaine runway, F0.60.71.21.01.01.01.00.91.01.0-1.0-1.0-0.5-0.51.0-1.10.21.0-0.6-0.60.60.2-0.2
Latency to leave start box in cocaine runway, M0.90.81.4-1.0-0.8-0.8-1.1-1.0-1.0-1.11.11.10.81.2-0.70.8-0.9-0.80.70.7-0.7-0.90.9
Std. dev. time between licks in bursts0.91.11.9-1.2-1.0-1.0-1.0-1.1-1.0-1.01.01.01.20.9-0.70.8-1.4-0.81.31.3-1.3-0.70.7
Total sessions with >9 infusions0.60.71.4-0.5-0.8-0.8-0.9-0.8-0.8-0.80.80.81.20.6-0.90.8-0.8-0.90.40.4-0.4-1.11.0
Short access day 1 total inactive lever presses0.40.51.5-0.3-0.4-0.4-0.6-0.5-0.5-0.50.60.61.10.8-0.70.7-0.9-0.70.40.4-0.4-1.21.2
Short access day 10 total inactive lever presses2.22.43.61.51.91.91.51.61.61.6-1.6-1.6-1.5-1.51.4-1.61.61.6-1.5-1.51.51.1-1.1
Short access day 1 total infusions2.22.33.5-1.3-1.6-1.6-1.6-1.5-1.5-1.51.51.51.91.5-1.71.4-1.7-1.41.31.3-1.3-1.71.7
Short access day 10 total infusions0.50.51.2-0.3-0.9-0.9-0.7-0.7-0.7-0.70.60.61.10.6-0.90.6-0.7-0.70.50.5-0.5-1.01.0
Short access total infusions0.30.30.9-0.3-0.7-0.7-0.6-0.5-0.5-0.50.50.51.00.7-0.50.4-0.7-0.50.20.2-0.2-0.60.6
Short access day 1 locomotion1.31.42.0-0.9-1.2-1.2-1.4-1.3-1.3-1.31.21.21.41.2-1.40.9-1.2-0.91.11.1-1.1-1.31.3
Short access day 10 total locomotion1.21.42.4-1.1-1.3-1.3-1.4-1.3-1.4-1.41.31.31.51.1-1.60.4-0.9-0.40.90.9-0.9-1.21.2
Short access total locomotion1.41.52.2-1.3-1.3-1.3-1.5-1.4-1.4-1.41.41.41.51.3-1.40.7-1.0-0.71.01.0-1.0-1.01.0
One hour access (0.3 mA shock)1.41.72.2-1.4-1.5-1.5-1.4-1.4-1.3-1.31.31.31.51.2-1.41.2-1.2-1.21.11.1-1.1-1.31.3
Compulsive drug intake1.21.21.8-1.1-1.0-1.0-1.0-1.1-1.0-1.01.01.01.01.0-0.91.2-1.2-1.21.31.3-1.3-0.90.9
One hour access (shock baseline)0.10.10.30.30.10.10.10.20.20.2-0.2-0.2-0.0-0.50.0-0.40.20.4-0.6-0.60.6-0.20.2
Social response proportion6.57.010.83.02.92.92.42.92.42.4-2.5-2.5-3.3-2.72.1-2.13.12.1-2.8-2.82.82.3-2.3
Social responses0.10.20.80.70.40.40.00.6-0.0-0.1-0.0-0.0-0.9-0.5-0.30.10.7-0.0-0.4-0.40.40.3-0.4
Social time0.81.01.81.40.90.91.00.90.70.7-0.9-0.9-1.3-1.20.8-0.91.40.9-0.9-0.90.91.1-1.1
Soleus weight0.20.41.30.90.70.70.80.80.70.7-0.8-0.8-0.5-1.20.4-0.80.40.80.20.2-0.20.4-0.4
Bone: stiffness0.20.30.50.70.50.50.50.60.50.5-0.5-0.5-0.7-0.60.6-0.40.30.4-0.5-0.50.50.3-0.3
Tibialis anterior weight2.27.49.52.62.82.82.83.02.82.8-2.8-2.8-2.8-2.92.6-3.12.63.1-2.4-2.42.42.3-2.3
Time to tail flick, vehicle, before self-admin4.95.08.42.42.42.42.52.92.52.6-2.5-2.5-1.5-2.22.1-2.01.81.9-2.4-2.42.41.2-1.2
Time to tail flick, vehicle, after self-admin0.20.20.50.30.50.50.40.60.30.4-0.5-0.5-0.4-0.50.0-0.70.40.7-0.6-0.60.60.4-0.4
Time to tail flick, test, before self-admin0.00.00.2-0.40.00.0-0.1-0.20.0-0.10.10.10.20.20.00.3-0.2-0.30.20.2-0.2-0.40.4
Time to tail flick, test, after self-admin0.20.31.6-0.2-0.1-0.1-0.1-0.0-0.1-0.20.00.01.30.6-0.3-0.3-0.30.2-0.3-0.30.3-1.11.1
Delta time to tail flick, vehicle, before/after SA1.81.82.8-1.4-1.4-1.4-1.5-1.7-1.5-1.51.51.51.11.4-1.61.1-1.2-1.01.41.4-1.4-0.90.9
Delta time to tail flick, test, before/after SA0.10.10.5-0.1-0.2-0.2-0.2-0.0-0.3-0.20.10.10.70.1-0.5-0.2-0.00.2-0.3-0.30.3-0.60.6
Tibia length3.29.112.53.43.23.23.33.13.43.4-3.3-3.3-3.4-3.53.3-2.32.42.2-2.5-2.52.52.7-2.7
Ambulatory time before self-admin0.40.40.90.50.60.60.70.40.50.6-0.7-0.7-0.8-1.00.5-0.30.90.3-0.7-0.70.70.7-0.7
Ambulatory time after self-admin0.70.71.3-1.0-0.8-0.8-0.8-1.1-0.9-0.70.90.90.31.0-0.50.9-0.8-0.81.11.1-1.10.2-0.2
Bone: tissue strength0.60.61.70.90.70.70.70.70.80.7-0.7-0.7-1.3-0.61.0-0.80.60.8-0.4-0.40.40.9-0.9
Total heroin consumption0.10.21.0-0.3-0.2-0.2-0.10.1-0.10.00.10.10.70.2-0.20.4-0.3-0.50.10.1-0.1-1.01.0
Bone: trabecular number0.50.71.5-0.9-0.8-0.8-0.8-1.1-0.8-0.80.80.81.00.7-0.40.6-1.2-0.61.21.2-1.2-0.50.5
Bone: trabecular spacing1.82.33.01.71.51.51.51.41.61.6-1.5-1.5-1.7-1.31.3-1.31.71.3-1.7-1.71.71.4-1.3
Bone: trabecular thickness0.10.10.6-0.20.20.20.20.30.20.2-0.2-0.20.7-0.20.4-0.8-0.10.7-0.2-0.20.20.1-0.2
Bone: trabecular tissue density0.60.91.70.60.90.90.91.20.80.8-0.9-0.9-1.0-0.51.2-0.80.60.8-1.0-1.01.01.3-1.3
Water consumed over 24 hours0.10.10.50.3-0.1-0.1-0.1-0.0-0.1-0.10.10.1-0.0-0.1-0.50.2-0.1-0.20.10.1-0.1-0.70.7
Number of responses in last shaping day2.22.33.7-1.4-1.4-1.4-1.6-1.5-1.4-1.41.41.41.51.0-1.81.9-1.4-1.91.41.4-1.4-1.91.9