Hub : Genes

Lrrfip2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Lrrfip2 0.06 0.04 2.0e-04 0.07 0.06 0.04 0.06 1.2e-04 6.0e-04 2.7e-03 4.4e-04
2 Brain intron excision ratio chr8_111091763_111110799 0.21 0.11 0.0e+00 0.18 0.2 0.2 0.2 8.0e-17 2.4e-18 5.3e-18 2.2e-18
3 NAcc intron excision ratio chr8_111091763_111110799 0.02 0.02 9.1e-04 0.02 0.02 0.02 0.02 8.9e-04 1.5e-03 5.4e-03 1.6e-03
4 RMTg alternative TSS XM_008766618.3 0.2 0.18 5.1e-03 0.02 0.02 0 0 8.9e-02 1.1e-01 3.2e-01 2.3e-01
5 NAcc gene expression Lrrfip2 0.1 0.06 7.3e-13 0.12 0.12 0.11 0.12 1.9e-13 3.4e-13 3.6e-13 1.9e-13
6 Brain alternative polyA NM_001395739.1 0.06 0.08 7.2e-04 0.05 0.03 0.03 0.04 3.5e-05 1.3e-03 1.7e-03 8.8e-05
7 Brain alternative polyA XM_008766616.3 0.05 0.07 7.0e-04 0.05 0.03 0.03 0.04 2.7e-05 8.9e-04 1.2e-03 6.2e-05
8 Brain alternative polyA NM_001395739.1 0.04 0.04 1.9e-03 0.04 0.02 0.02 0.03 1.4e-04 4.0e-03 6.8e-03 3.9e-04
9 Brain alternative polyA XM_008766616.3 0.04 0.05 1.3e-03 0.04 0.02 0.02 0.04 8.0e-05 2.4e-03 2.9e-03 1.9e-04
10 Liver gene expression Lrrfip2 0.07 0.04 4.3e-09 0.07 0.07 0.07 0.07 5.7e-08 1.1e-08 3.0e-08 2.6e-08
11 PL gene expression Lrrfip2 0.07 0.04 1.6e-11 0.1 0.1 0.1 0.1 6.6e-11 3.4e-11 1.1e-10 5.3e-11
12 RMTg alternative TSS XM_008766618.3 0.23 0.2 2.7e-03 0.03 0.03 0.01 0.02 7.2e-02 4.2e-02 2.0e-01 1.1e-01
13 Liver intron excision ratio chr8_111091763_111110799 0.24 0.1 1.1e-16 0.13 0.14 0.14 0.15 1.1e-14 2.5e-15 2.1e-15 4.6e-16
14 Brain gene expression Lrrfip2 0.11 0.07 4.6e-11 0.1 0.13 0.1 0.11 6.8e-10 1.0e-11 1.6e-09 1.2e-10
15 pVTA intron excision ratio chr8_111091763_111110799 0.17 0.1 1.0e-07 0.12 0.16 0.13 0.13 8.4e-06 1.7e-07 2.4e-06 2.2e-06
16 Brain intron excision ratio chr8_111091763_111093020 0.32 0.16 4.5e-06 0.05 0.06 0.05 0.06 1.2e-05 1.7e-06 1.5e-05 2.6e-06
17 Adipose intron excision ratio chr8_111091763_111110799 0.12 0.08 1.5e-04 0.02 0.02 0.02 0.02 2.5e-03 4.5e-03 3.3e-03 6.1e-03
18 Liver intron excision ratio chr8_111093091_111110799 0.07 0.05 2.4e-06 0.05 0.04 0.03 0.04 1.3e-06 4.9e-05 1.7e-04 1.6e-05
19 PL intron excision ratio chr8_111091763_111110799 0.09 0.07 7.3e-06 0.04 0.03 0.04 0.04 2.0e-05 3.6e-04 1.7e-05 9.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.00.10.70.20.2-0.2-0.2-0.30.2-0.20.2-0.2-0.3-0.10.20.3-0.20.30.1-0.10.1-0.8
Area under the delay curve2.02.12.7-1.5-1.51.51.51.3-1.51.5-1.51.51.41.6-1.5-1.41.5-1.41.51.4-1.40.8
BMI with tail0.92.89.61.41.6-1.8-1.8-1.80.8-0.80.8-0.8-1.5-1.51.52.2-1.01.4-3.1-2.42.4-1.4
BMI without tail2.24.57.92.02.2-2.2-2.1-2.01.9-1.91.9-1.9-2.1-2.12.02.4-1.82.0-2.8-2.52.5-1.7
Body weight7.330.537.95.65.7-5.8-5.7-5.85.2-5.25.2-5.2-5.5-5.65.55.9-5.15.4-6.2-5.75.7-4.5
Weight adjusted by age0.30.40.70.40.5-0.5-0.7-0.70.5-0.50.5-0.5-0.5-0.60.60.8-0.50.5-0.8-0.80.8-0.2
Bone surface0.00.10.2-0.2-0.10.20.20.1-0.30.3-0.30.30.20.3-0.3-0.00.3-0.3-0.10.3-0.3-0.5
Bone volume0.00.00.6-0.00.10.00.0-0.1-0.20.2-0.20.20.00.2-0.10.20.1-0.1-0.20.1-0.1-0.8
Breakpoint value in progressive ratio session0.00.00.20.30.2-0.3-0.20.20.2-0.20.2-0.2-0.2-0.10.10.3-0.20.2-0.1-0.00.0-0.4
Number of licking bursts0.20.21.0-0.4-0.40.40.40.5-0.40.4-0.40.40.50.3-0.4-0.30.4-0.50.1-0.00.01.0
Context. condit. distance diff. score0.00.00.20.00.0-0.0-0.0-0.00.0-0.00.0-0.00.10.0-0.0-0.10.1-0.1-0.10.5-0.5-0.3
Locomotion velocity, session 10.10.10.2-0.1-0.20.20.20.4-0.30.3-0.30.30.20.2-0.2-0.20.2-0.20.10.4-0.4-0.1
Locomotion distance, session 11.01.33.91.31.3-1.3-1.3-1.10.8-0.80.8-0.8-1.3-1.01.11.2-1.01.1-1.4-0.60.6-2.0
Locomotion velocity, session 20.20.20.4-0.4-0.30.40.40.5-0.70.7-0.70.70.50.6-0.6-0.20.6-0.6-0.10.5-0.5-0.3
Locomotion distance, session 20.10.11.30.20.3-0.2-0.2-0.2-0.30.3-0.30.3-0.30.10.10.4-0.00.2-0.5-0.10.1-1.1
Locomotion velocity, session 30.20.31.90.40.4-0.5-0.5-0.40.2-0.20.2-0.2-0.5-0.20.30.8-0.20.4-0.9-0.30.3-1.4
Locomotion distance, session 30.70.81.4-0.8-0.80.70.70.7-1.21.2-1.21.20.81.1-0.9-0.41.1-0.80.20.9-0.9-0.8
Stereotopy head waving bouts, day 30.10.11.00.20.1-0.2-0.2-0.10.2-0.20.2-0.2-0.1-0.40.20.0-0.10.1-0.5-0.50.51.0
Stereotopy head waving duration, day 30.30.30.60.50.5-0.5-0.5-0.40.6-0.60.6-0.6-0.4-0.70.60.2-0.60.5-0.3-0.60.60.8
Locomotion velocity, session 70.30.41.30.50.6-0.6-0.6-0.60.6-0.60.6-0.6-0.7-0.40.60.5-0.70.7-0.0-0.30.3-1.1
Locomotion distance, session 70.50.71.3-0.8-0.70.70.70.6-0.90.9-0.90.90.70.9-0.8-0.90.7-0.71.01.2-1.2-0.1
Stereotopy head waving bouts, day 70.10.10.4-0.3-0.40.40.40.4-0.20.2-0.20.20.30.5-0.4-0.20.3-0.30.60.1-0.1-0.0
Stereotopy head waving duration, day 70.20.30.50.50.4-0.4-0.4-0.40.5-0.50.5-0.5-0.5-0.30.40.7-0.50.5-0.3-0.60.6-0.7
Locomotion velocity, session 80.50.64.10.70.7-0.8-0.8-0.70.3-0.30.3-0.3-0.7-0.40.51.0-0.40.5-1.3-0.20.2-2.0
Locomotion distance, session 80.40.74.40.80.9-0.9-0.9-0.80.3-0.30.3-0.3-0.8-0.50.60.9-0.50.7-1.1-0.20.2-2.1
Degree of sensitization distance1.01.01.61.01.1-0.9-0.9-0.91.2-1.21.2-1.2-1.0-1.21.10.4-1.31.1-0.2-0.80.80.1
Degree of sensitization stereotypy0.10.10.4-0.1-0.10.20.20.20.2-0.20.2-0.2-0.00.3-0.10.1-0.0-0.00.60.0-0.0-0.6
Conditioned locomotion2.93.44.1-2.0-2.02.01.91.9-1.81.8-1.81.81.92.0-1.9-1.71.8-1.82.01.6-1.61.5
Cocaine response after cond. corrected0.20.20.50.40.4-0.4-0.4-0.50.5-0.50.5-0.5-0.4-0.70.50.0-0.50.4-0.6-0.40.40.6
Cocaine response after cond. not corrected1.71.92.71.31.4-1.3-1.3-1.41.4-1.41.4-1.4-1.4-1.61.51.2-1.41.4-1.6-1.51.5-0.2
Cocaine response before conditioning1.41.73.11.31.3-1.3-1.3-1.21.1-1.11.1-1.1-1.3-1.21.21.8-1.11.2-1.6-1.61.6-1.6
Saline control response1.21.62.41.21.3-1.3-1.4-1.41.4-1.41.4-1.4-1.4-1.31.40.8-1.51.5-0.2-0.80.8-1.1
Bone: connectivity density0.30.41.4-0.7-0.70.70.70.6-0.50.5-0.50.50.50.7-0.6-0.80.4-0.51.20.8-0.80.2
Bone: cortical apparent density0.40.61.4-0.7-0.70.80.80.7-0.40.4-0.40.40.70.8-0.8-0.70.7-0.81.11.2-1.2-0.2
Bone: cortical area0.10.20.3-0.4-0.30.40.40.3-0.40.4-0.40.40.50.3-0.50.10.6-0.6-0.1-0.10.10.4
Bone: cortical porosity0.10.11.5-0.3-0.30.40.40.4-0.10.1-0.10.10.10.3-0.1-0.3-0.10.01.20.1-0.10.3
Bone: cortical porosity0.20.31.9-0.5-0.50.50.50.5-0.30.3-0.30.30.30.5-0.3-0.50.1-0.11.40.1-0.10.7
Bone: cortical thickness0.10.20.70.40.4-0.4-0.4-0.50.4-0.40.4-0.4-0.2-0.40.20.7-0.10.1-0.8-0.50.5-0.5
Bone: cortical thickness0.00.00.10.10.1-0.1-0.1-0.10.1-0.10.1-0.1-0.1-0.10.10.2-0.10.10.0-0.20.2-0.2
Bone: cortical tissue density0.40.61.4-0.7-0.70.80.80.8-0.50.5-0.50.50.70.9-0.8-0.70.7-0.81.11.2-1.2-0.2
Condit. Reinf. active minus inactive responses0.10.10.20.20.2-0.1-0.1-0.10.4-0.40.4-0.4-0.2-0.30.3-0.1-0.40.20.3-0.10.10.2
Condit. Reinf. active-inactive response ratio0.10.20.40.40.4-0.3-0.3-0.30.6-0.60.6-0.6-0.3-0.50.40.0-0.50.40.1-0.20.20.3
Condit. Reinf. active responses0.10.10.2-0.4-0.30.30.30.3-0.00.0-0.00.00.30.2-0.2-0.30.2-0.20.50.0-0.00.5
Condit. Reinf. inactive responses0.50.61.0-1.0-1.00.90.90.9-0.80.8-0.80.80.80.9-0.9-0.51.0-0.90.50.3-0.30.5
Incentive salience index mean0.10.10.1-0.3-0.20.30.30.3-0.30.3-0.30.30.30.2-0.2-0.30.2-0.20.30.2-0.20.3
Condit. Reinf. lever presses1.21.62.4-1.3-1.31.31.31.3-1.61.6-1.61.61.31.4-1.3-1.11.3-1.20.90.9-0.90.8
Condit. Reinf. active minus inactive responses2.02.53.71.81.8-1.7-1.7-1.81.5-1.51.5-1.5-1.6-1.61.61.4-1.51.5-1.8-0.70.7-1.9
Condit. Reinf. active-inactive response ratio1.71.83.11.51.5-1.4-1.4-1.41.2-1.21.2-1.2-1.3-1.51.41.3-1.21.3-1.8-1.21.2-0.8
Condit. Reinf. active responses1.42.02.81.71.7-1.6-1.6-1.61.5-1.51.5-1.5-1.5-1.51.51.0-1.41.4-1.4-0.30.3-1.6
Condit. Reinf. inactive responses0.20.21.4-0.1-0.20.20.20.3-0.10.1-0.10.10.30.2-0.2-0.70.2-0.30.61.2-1.2-0.3
Condit. Reinf. lever presses2.33.24.52.12.1-2.0-2.0-2.01.7-1.71.7-1.7-1.8-1.81.81.5-1.71.7-2.0-0.80.8-2.1
Condit. Reinf. lever reinforcers received1.72.43.31.81.8-1.8-1.8-1.71.6-1.61.6-1.6-1.6-1.71.61.1-1.61.5-1.5-0.50.5-1.7
Conditioned reinforcement - actives0.30.30.7-0.7-0.60.10.10.7-0.70.7-0.70.70.30.3-0.2-0.80.3-0.20.40.7-0.70.7
Conditioned reinforcement - inactives0.80.92.9-1.0-1.00.60.71.1-1.01.0-1.01.01.00.7-0.9-0.91.0-1.00.30.6-0.61.7
Conditioned locomotion0.40.51.4-0.8-0.70.40.20.7-0.80.8-0.80.80.40.6-0.4-1.20.4-0.30.80.8-0.80.8
Patch foraging indifference point 0 sec1.11.82.41.41.3-1.5-1.6-1.31.3-1.31.3-1.3-1.4-1.31.41.4-1.51.5-0.7-1.41.4-1.3
Patch foraging indifference point AUC0.10.21.50.20.3-0.3-0.3-0.40.3-0.30.3-0.3-0.30.00.20.1-0.20.30.10.5-0.5-1.2
Delay disc. indifference point, 0s delay0.00.10.3-0.1-0.1-0.4-0.5-0.2-0.20.2-0.20.20.00.10.00.10.10.10.0-0.30.30.2
Delay disc. indifference point, 16s delay1.11.12.0-1.0-1.01.31.41.0-1.01.0-1.01.01.01.1-1.0-1.01.0-1.01.11.0-1.00.4
Delay disc. indifference point, 2s delay0.20.30.4-0.6-0.60.20.30.5-0.50.5-0.50.50.50.6-0.5-0.60.6-0.50.50.6-0.60.4
Delay disc. indifference point, 24s delay1.01.01.4-0.9-1.01.11.21.1-0.90.9-0.90.90.91.0-1.0-1.10.9-0.91.01.1-1.10.6
Delay disc. indifference point, 4s delay2.12.22.7-1.6-1.61.41.31.4-1.41.4-1.41.41.51.6-1.6-1.51.6-1.51.41.6-1.60.9
Delay disc. indifference point, 8s delay1.91.92.5-1.5-1.51.61.61.2-1.51.5-1.51.51.41.6-1.4-1.31.4-1.31.51.3-1.30.8
Indifference point function ln k0.20.20.8-0.1-0.20.20.10.3-0.70.7-0.70.70.20.1-0.30.30.4-0.3-0.9-0.60.60.3
Indifference point function log k0.20.20.8-0.1-0.20.20.10.3-0.70.7-0.70.70.20.1-0.30.30.4-0.3-0.9-0.60.60.3
Patch foraging total patch changes 0 sec1.32.22.81.51.5-1.6-1.7-1.51.4-1.41.4-1.4-1.5-1.41.61.5-1.61.6-0.9-1.51.5-1.2
Patch foraging total patch changes 12 sec0.60.81.41.10.9-1.0-0.9-0.71.2-1.21.2-1.2-1.0-0.90.90.6-1.00.9-0.3-0.00.0-0.8
Patch foraging total patch changes 18 sec2.33.04.31.61.7-1.8-1.7-1.71.8-1.81.8-1.8-1.9-1.72.01.7-2.02.1-0.7-1.31.3-1.8
Patch foraging total patch changes 24 sec2.83.44.42.12.0-1.8-1.8-1.81.9-1.91.9-1.9-1.9-1.91.91.8-1.91.9-1.6-1.51.5-1.5
Patch foraging total patch changes 6 sec0.10.20.30.50.4-0.4-0.5-0.30.5-0.50.5-0.5-0.5-0.20.40.2-0.50.50.4-0.10.1-0.5
Patch foraging time to switch 0 sec0.30.41.7-0.5-0.70.90.91.0-0.40.4-0.40.40.60.4-0.6-0.70.5-0.70.50.4-0.41.3
Patch foraging water rate 0 sec0.20.30.70.50.6-0.8-0.8-0.70.4-0.40.4-0.4-0.6-0.60.60.6-0.50.6-0.6-0.30.3-0.7
Patch foraging water rate 12 sec0.40.61.00.91.0-0.8-0.8-0.80.7-0.70.7-0.7-0.7-0.80.70.7-0.70.6-1.0-0.70.7-0.5
Patch foraging water rate 18 sec0.50.73.20.40.6-0.6-0.7-0.90.1-0.10.1-0.1-0.3-0.50.41.2-0.10.3-1.5-1.81.80.0
Patch foraging water rate 24 sec0.91.22.00.91.0-1.2-1.2-1.21.1-1.11.1-1.1-0.9-1.00.91.2-0.90.9-1.0-1.41.4-0.8
Patch foraging water rate 6 sec0.40.61.81.00.9-0.6-0.6-0.70.6-0.60.6-0.6-0.7-0.60.60.9-0.60.7-0.9-0.50.5-1.3
Seeking ratio, delayed vs. immediate footshock1.72.03.1-1.4-1.41.21.20.9-1.81.8-1.81.81.51.6-1.4-1.51.5-1.31.51.0-1.00.9
Distance traveled before self-admin0.10.20.60.10.30.1-0.4-0.70.1-0.10.1-0.1-0.1-0.30.30.4-0.10.2-0.6-0.80.80.2
Distance traveled after self-admin0.40.51.3-0.4-0.51.10.91.0-0.40.4-0.40.40.60.5-0.6-0.70.5-0.70.31.0-1.00.5
Extensor digitorum longus weight0.20.60.9-0.8-0.70.70.70.7-0.90.9-0.90.90.80.6-0.7-0.80.8-0.80.40.5-0.51.0
Bone: elastic displacement0.10.10.20.30.2-0.2-0.2-0.20.2-0.20.2-0.2-0.1-0.30.20.5-0.10.1-0.5-0.40.40.0
Bone: elastic work0.81.02.81.01.0-1.0-1.0-1.00.7-0.70.7-0.7-0.8-0.90.81.5-0.60.7-1.7-1.21.2-1.1
Bone: endosteal estimation0.10.30.80.50.5-0.4-0.4-0.50.4-0.40.4-0.4-0.5-0.50.50.6-0.60.6-0.2-0.90.9-0.2
Bone: endosteal perimeter0.91.92.6-1.5-1.51.51.51.5-1.61.6-1.61.61.41.4-1.4-1.01.5-1.41.00.6-0.61.5
Epididymis fat weight0.51.12.90.60.8-1.1-1.1-1.30.8-0.80.8-0.8-0.9-0.80.91.4-0.81.0-1.0-1.71.7-0.9
Delta time in closed arm before/after self-admin0.10.10.2-0.3-0.30.40.1-0.1-0.40.4-0.40.40.20.3-0.3-0.20.3-0.20.3-0.00.00.0
Delta time in open arm before/after self-admin0.20.20.40.50.4-0.4-0.00.30.6-0.60.6-0.6-0.4-0.30.30.3-0.50.3-0.10.3-0.3-0.6
Diff in mean of infusions in LGA sessions0.10.10.3-0.2-0.20.10.20.3-0.10.1-0.10.10.30.0-0.2-0.30.3-0.4-0.30.3-0.30.6
Delay discount exponential model param2.42.53.11.71.7-1.6-1.6-1.51.6-1.61.6-1.6-1.6-1.81.61.6-1.61.5-1.6-1.61.6-0.9
Extinction: sum of active levers before priming0.20.20.70.10.3-0.8-0.6-0.70.1-0.10.1-0.1-0.4-0.20.40.5-0.30.5-0.0-0.80.8-0.4
Active lever presses in extinction session 60.60.61.30.50.7-0.9-0.9-1.10.6-0.60.6-0.6-0.7-0.60.80.7-0.70.9-0.3-1.01.0-0.8
Bone: final force0.91.52.91.21.3-1.1-1.1-1.21.1-1.11.1-1.1-1.1-1.21.11.6-1.01.0-1.5-1.71.7-0.9
Bone: final moment1.32.03.81.41.5-1.3-1.3-1.41.3-1.31.3-1.3-1.3-1.41.31.8-1.11.2-1.7-2.02.0-1.0
Food consumed during 24 hour testing period1.72.03.91.41.4-1.4-1.4-1.41.2-1.21.2-1.2-1.4-1.51.41.6-1.31.4-1.6-2.02.0-0.4
Glucose0.20.30.70.60.6-0.5-0.5-0.60.6-0.60.6-0.6-0.7-0.50.60.4-0.70.7-0.3-0.30.3-0.8
Heart weight2.12.94.32.11.9-1.7-1.6-1.81.9-1.91.9-1.9-1.7-1.91.71.4-1.71.5-1.8-1.41.4-0.9
Delay discount hyperbolic model param2.42.53.11.71.7-1.6-1.6-1.51.6-1.61.6-1.6-1.6-1.81.61.6-1.61.5-1.6-1.61.6-0.9
Intermittent access intake day 1-15 change0.60.61.4-0.8-0.80.50.80.8-0.80.8-0.80.80.80.5-0.6-0.80.8-0.70.20.8-0.81.2
Intermittent access intake escalation0.40.41.0-0.7-0.70.50.60.7-0.70.7-0.70.70.70.4-0.5-0.70.6-0.60.10.7-0.71.0
Intermittent access intake escalation 20.10.10.50.10.1-0.00.20.20.1-0.10.1-0.1-0.0-0.40.2-0.2-0.1-0.0-0.50.2-0.20.7
Intermitt. access day 1 inactive lever presses0.00.00.2-0.00.0-0.1-0.1-0.0-0.00.0-0.00.00.0-0.0-0.0-0.00.0-0.0-0.1-0.30.30.5
Intermitt. access day 15 inactive lever presses0.60.61.2-0.8-0.80.70.90.8-0.80.8-0.80.81.00.8-1.0-0.41.1-1.10.20.2-0.21.1
Intermitt. access escalation Index0.10.10.30.00.20.20.2-0.60.0-0.00.0-0.0-0.20.00.10.3-0.20.30.2-0.40.4-0.6
Intermittent access day 1 total infusions0.00.00.0-0.2-0.00.0-0.1-0.2-0.20.2-0.20.2-0.00.00.00.0-0.00.10.0-0.20.2-0.1
Intermittent access day 15 total infusions0.20.20.4-0.7-0.50.40.30.3-0.70.7-0.70.70.40.3-0.3-0.60.4-0.30.20.4-0.40.6
Intermittent access terminal intake (last 3 days)0.10.10.2-0.5-0.30.20.20.1-0.50.5-0.50.50.20.1-0.0-0.30.1-0.00.1-0.00.00.4
Intermittent access total infusions0.20.30.6-0.8-0.60.30.20.2-0.80.8-0.80.80.50.4-0.3-0.50.5-0.30.30.2-0.20.4
Intermittent access day 1 locomotion0.20.20.5-0.3-0.30.30.30.6-0.30.3-0.30.30.30.3-0.3-0.70.2-0.30.50.5-0.50.5
Intermittent access day 15 total locomotion0.50.50.8-0.8-0.70.70.70.7-0.80.8-0.80.80.60.6-0.6-0.90.5-0.50.80.5-0.50.8
Intermittent access total locomotion0.91.11.5-1.2-1.10.90.70.9-1.21.2-1.21.20.91.1-0.9-1.20.9-0.81.10.8-0.80.9
Intermittent access standard deviation0.20.20.70.40.3-0.3-0.30.20.4-0.40.4-0.4-0.3-0.60.40.1-0.30.2-0.80.1-0.10.6
Left kidney weight0.72.14.21.61.6-1.5-1.4-1.51.3-1.31.3-1.3-1.6-1.21.31.4-1.31.4-1.7-1.21.2-2.0
Right kidney weight0.20.61.90.80.7-1.0-0.8-1.00.6-0.60.6-0.6-0.9-0.60.70.6-0.60.8-0.9-0.50.5-1.4
Cocaine induced anxiety0.60.61.2-0.8-0.80.80.80.9-0.80.8-0.80.80.90.7-0.8-0.80.8-0.90.50.5-0.51.1
Post-drug Anxiety0.30.41.0-0.4-0.50.70.70.6-0.40.4-0.40.40.60.5-0.6-0.80.6-0.70.60.5-0.51.0
Baseline Anxiety0.10.10.2-0.3-0.30.50.40.2-0.30.3-0.30.30.40.4-0.4-0.30.4-0.40.40.3-0.30.2
Tail length6.218.623.44.54.6-4.5-4.5-4.34.8-4.84.8-4.8-4.5-4.44.43.9-4.54.4-3.4-3.43.4-3.6
Length with tail8.932.537.06.16.1-5.9-5.8-5.96.1-6.16.1-6.1-5.9-5.95.85.4-5.85.7-4.9-4.84.8-4.9
Length without tail6.414.117.23.93.9-4.0-3.9-4.23.6-3.63.6-3.6-3.8-3.83.83.9-3.73.8-3.5-3.63.6-3.3
Times rat made contact with spout0.30.40.50.60.6-0.6-0.6-0.60.7-0.70.7-0.7-0.6-0.70.60.4-0.70.6-0.4-0.70.70.1
Lifetime Intake0.20.20.5-0.7-0.50.30.10.2-0.70.7-0.70.70.40.4-0.3-0.50.4-0.30.30.1-0.10.5
Liver weight, left0.10.10.70.10.1-0.0-0.0-0.20.5-0.50.5-0.5-0.2-0.00.20.0-0.40.30.9-0.30.3-0.2
Liver weight, right1.32.22.81.31.5-1.5-1.6-1.71.5-1.51.5-1.5-1.5-1.31.41.5-1.41.5-1.2-1.51.5-1.5
Locomotor activity5.79.010.53.13.1-3.1-3.2-2.93.1-3.13.1-3.1-3.1-3.23.12.9-3.13.1-2.9-2.72.7-2.3
Locomotor testing distance5.59.110.93.13.1-3.2-3.1-2.83.0-3.03.0-3.0-3.2-3.33.22.9-3.23.1-3.1-2.82.8-2.1
Locomotor testing rearing0.30.40.70.60.7-0.8-0.7-0.60.6-0.60.6-0.6-0.7-0.80.80.4-0.80.8-0.3-0.60.6-0.1
Locomotion in novel chamber0.10.20.3-0.5-0.5-0.1-0.00.3-0.50.5-0.50.50.40.3-0.3-0.30.4-0.30.20.4-0.40.4
Locomotion in novel chamber post-restriction0.70.91.31.00.9-1.2-0.7-0.81.0-1.01.0-1.0-1.0-0.91.01.0-1.11.1-0.6-0.90.9-0.8
Fecal boli incidents, locomotor time 10.40.50.80.70.8-0.9-0.8-0.90.6-0.60.6-0.6-0.7-0.70.70.7-0.60.7-0.7-0.40.4-0.7
Change in fecal boli incidents, locomotor task0.10.10.50.20.1-0.5-0.7-0.30.2-0.20.2-0.2-0.2-0.10.20.4-0.20.3-0.1-0.50.5-0.2
Time >=10cm from walls, locomotor time 10.20.20.6-0.4-0.30.70.80.3-0.30.3-0.30.30.40.5-0.4-0.30.3-0.40.60.2-0.2-0.0
Bouts of movement, locomotor time 10.00.10.30.00.10.40.40.20.1-0.10.1-0.1-0.0-0.0-0.0-0.2-0.1-0.00.10.5-0.5-0.1
Total resting periods, locomotor time 10.00.00.20.00.10.30.40.10.1-0.10.1-0.1-0.0-0.10.1-0.0-0.10.00.00.3-0.3-0.1
Rest time, locomotor task time 10.40.40.9-1.0-0.70.40.50.4-0.90.9-0.90.90.60.7-0.5-0.70.6-0.50.70.3-0.30.7
Distance moved, locomotor task time 11.61.72.41.41.4-1.2-1.4-1.01.4-1.41.4-1.4-1.2-1.31.21.5-1.21.1-1.5-1.41.4-0.9
Vertical activity count, locomotor time 10.60.71.01.00.9-0.6-0.8-0.51.0-1.01.0-1.0-0.8-0.80.70.9-0.80.6-0.8-0.70.7-0.7
Time >=10cm from walls, locomotor time 21.61.72.61.31.4-1.6-1.5-1.51.3-1.31.3-1.3-1.3-1.21.21.4-1.21.2-1.1-1.31.3-1.3
Bouts of movement, locomotor time 20.10.10.50.20.1-0.4-0.4-0.40.0-0.00.0-0.0-0.2-0.30.30.6-0.10.2-0.7-0.60.6-0.2
Total resting periods, locomotor time 20.10.10.2-0.1-0.1-0.1-0.1-0.1-0.20.2-0.20.20.10.00.00.40.20.0-0.5-0.40.40.0
Rest time, locomotor task time 20.00.00.1-0.3-0.20.20.30.3-0.20.2-0.20.20.10.2-0.00.10.10.00.10.1-0.10.0
Distance moved, locomotor task time 20.80.91.31.01.1-1.0-1.0-1.01.1-1.11.1-1.1-0.9-1.00.80.9-0.90.7-1.0-1.01.0-0.4
Vertical activity count, locomotor time 20.00.00.10.30.4-0.0-0.0-0.20.3-0.30.3-0.3-0.2-0.20.10.0-0.20.0-0.2-0.20.20.0
Light reinforcement 10.71.32.01.11.1-1.1-1.2-1.11.2-1.21.2-1.2-1.1-1.11.01.3-1.01.0-1.2-1.41.4-0.7
Light reinforcement 20.10.10.2-0.1-0.20.2-0.0-0.1-0.30.3-0.30.30.10.4-0.40.10.4-0.2-0.2-0.40.4-0.3
Bone: marrow area0.10.30.80.50.5-0.5-0.5-0.50.5-0.50.5-0.5-0.6-0.50.60.7-0.60.6-0.2-0.90.9-0.2
Bone: maximum diameter0.40.70.9-0.8-0.80.80.80.8-0.90.9-0.90.90.90.8-0.9-0.61.0-0.90.40.5-0.50.8
Bone: maximum force0.81.53.21.11.2-1.1-1.1-1.21.1-1.11.1-1.1-1.1-1.11.11.6-1.01.0-1.2-1.81.8-0.9
Bone: maximum moment1.01.73.71.21.3-1.2-1.2-1.31.2-1.21.2-1.2-1.1-1.21.21.7-1.11.1-1.3-1.91.9-0.8
Mean time between licks in bursts1.11.52.0-1.1-1.21.11.11.2-1.41.4-1.41.41.21.1-1.1-1.41.2-1.20.71.4-1.41.2
Mean num. licks in bursts0.50.60.80.80.8-0.8-0.8-0.90.8-0.80.8-0.8-0.9-0.70.80.6-0.90.9-0.4-0.50.5-0.9
Cd content in liver1.82.03.01.51.4-1.5-1.5-1.41.7-1.71.7-1.7-1.4-1.71.61.0-1.71.6-0.6-1.01.0-0.4
Co content in liver0.00.10.20.20.2-0.1-0.1-0.20.1-0.10.1-0.1-0.1-0.20.10.4-0.10.1-0.3-0.50.5-0.2
Cu content in liver4.15.06.32.22.2-2.2-2.2-2.22.2-2.22.2-2.2-2.3-2.32.42.4-2.32.4-1.8-2.52.5-1.4
Fe content in liver1.21.42.41.21.1-1.1-1.1-1.11.5-1.51.5-1.5-1.1-1.31.30.9-1.41.2-0.0-0.70.7-0.8
K content in liver0.80.83.91.00.9-0.9-0.9-0.80.8-0.80.8-0.8-0.8-0.60.71.0-0.60.7-1.1-0.30.3-2.0
Mg content in liver0.20.22.30.30.2-0.2-0.2-0.1-0.10.1-0.10.1-0.10.1-0.10.20.2-0.1-0.70.7-0.7-1.5
Mn content in liver0.91.04.41.11.1-1.0-1.0-1.00.7-0.70.7-0.7-1.0-0.70.81.1-0.80.9-1.1-0.40.4-2.1
Na content in liver0.20.30.60.40.4-0.4-0.4-0.30.7-0.70.7-0.7-0.4-0.40.40.3-0.60.40.40.0-0.0-0.7
Rb content in liver0.80.91.90.90.8-0.8-0.8-0.71.4-1.41.4-1.4-0.8-1.21.10.5-1.31.00.4-0.60.60.4
Se content in liver0.10.10.90.00.1-0.2-0.2-0.10.2-0.20.2-0.2-0.00.1-0.10.10.1-0.1-0.30.5-0.5-0.9
Sr content in liver0.20.21.50.30.3-0.3-0.3-0.3-0.10.1-0.10.1-0.3-0.10.20.60.00.2-1.2-0.60.6-0.5
Zn content in liver5.15.78.22.42.4-2.4-2.4-2.42.1-2.12.1-2.1-2.4-2.32.42.9-2.32.4-2.3-2.92.9-2.1
Bone: minimum diameter0.20.40.7-0.7-0.60.70.70.6-0.80.8-0.80.80.70.6-0.7-0.20.8-0.70.1-0.20.20.8
Time in familiar zone, hab. session 11.41.42.4-1.2-1.21.11.11.1-1.01.0-1.01.01.21.0-1.0-1.41.0-1.11.41.2-1.21.5
Time in novel zone, hab. session 10.50.50.70.70.7-0.6-0.6-0.50.8-0.80.8-0.8-0.7-0.70.60.6-0.60.6-0.8-0.80.8-0.3
Total zone transitions, hab. session 10.81.12.01.11.2-1.1-1.1-1.10.7-0.70.7-0.7-1.2-0.91.01.2-0.91.1-1.4-1.11.1-1.4
Total locomotion distance, hab. session 10.30.40.80.60.7-0.7-0.7-0.70.5-0.50.5-0.5-0.7-0.50.60.6-0.50.6-0.8-0.50.5-0.9
Locomotion velocity, hab. session 10.30.51.70.70.7-0.7-0.7-0.70.5-0.50.5-0.5-0.7-0.50.60.8-0.60.7-0.7-0.50.5-1.3
Time in familiar zone, hab. session 20.50.51.1-0.6-0.60.60.60.7-0.80.8-0.80.80.80.6-0.7-0.70.7-0.80.51.0-1.00.3
Time in novel zone, hab. session 20.10.10.50.10.1-0.0-0.0-0.10.2-0.20.2-0.2-0.3-0.20.30.0-0.30.30.1-0.70.70.7
Total zone transitions, hab. session 20.20.21.20.60.6-0.5-0.5-0.40.0-0.00.0-0.0-0.5-0.30.40.5-0.30.4-1.1-0.40.4-0.8
Total locomotion distance, hab. session 20.30.41.50.70.7-0.7-0.7-0.70.4-0.40.4-0.4-0.7-0.50.60.8-0.50.6-0.9-0.50.5-1.2
Locomotion velocity, hab. session 20.20.31.80.60.6-0.5-0.5-0.50.3-0.30.3-0.3-0.5-0.30.40.6-0.40.4-0.7-0.20.2-1.3
Novel to familiar place preference ratio1.01.01.61.01.1-1.0-1.0-1.00.9-0.90.9-0.9-1.2-0.91.11.0-1.21.3-0.3-1.11.1-1.2
Novelty place preference1.01.01.51.01.1-0.9-0.9-1.00.9-0.90.9-0.9-1.2-0.81.10.9-1.21.2-0.1-1.01.0-1.1
Time in novel zone, NPP test1.21.21.91.11.2-1.1-1.1-1.11.0-1.01.0-1.0-1.3-1.01.21.0-1.41.4-0.2-1.21.2-1.0
Total zone transitions, NPP test2.84.07.12.22.2-2.2-2.2-2.11.5-1.51.5-1.5-2.2-1.81.92.1-1.82.0-2.7-1.71.7-2.7
Total locomotion distance, NPP test1.11.52.61.31.3-1.3-1.3-1.41.0-1.01.0-1.0-1.3-1.11.21.3-1.11.2-1.6-1.11.1-1.6
Locomotion velocity, NPP test1.21.74.01.41.4-1.4-1.4-1.41.0-1.01.0-1.0-1.4-1.11.21.5-1.11.2-1.6-1.11.1-2.0
Intraocular pressure0.91.22.01.01.0-1.0-1.1-1.11.4-1.41.4-1.4-1.1-1.21.20.7-1.41.20.1-1.01.0-0.2
Delta distance traveled before/after self-admin0.50.51.8-0.3-0.50.60.91.2-0.40.4-0.40.40.50.6-0.7-0.90.5-0.70.71.3-1.30.2
Delta ambulatory time before/after self-admin0.20.20.40.60.4-0.20.30.50.6-0.60.6-0.6-0.4-0.30.2-0.1-0.50.2-0.10.6-0.6-0.5
Parametrial fat weight0.91.72.41.41.3-1.1-1.0-0.81.5-1.51.5-1.5-1.4-1.31.31.3-1.41.3-1.3-1.31.3-0.6
Pavlov. Cond. lever latency4.65.87.72.52.4-2.5-2.5-2.32.8-2.82.8-2.8-2.5-2.62.62.0-2.72.5-1.5-2.22.2-1.0
Pavlov. Cond. magazine entry latency6.28.09.3-2.8-2.92.92.93.0-3.03.0-3.03.02.92.9-2.9-2.63.0-2.92.02.8-2.81.8
Pavlov. Cond. change in total contacts1.61.82.1-1.4-1.41.31.31.2-1.41.4-1.41.41.41.4-1.4-1.11.4-1.31.31.4-1.40.4
Pavlov. Cond. index score6.27.89.3-2.8-2.82.92.92.8-3.03.0-3.03.02.92.9-2.9-2.53.0-2.92.02.8-2.81.5
Pavlov. Cond. latency score5.97.59.1-2.7-2.72.82.82.8-3.03.0-3.03.02.82.9-2.9-2.42.9-2.92.02.8-2.81.3
Pavlov. Cond. lever contacts2.73.14.4-1.8-1.81.81.81.7-2.12.1-2.12.11.81.9-1.9-1.42.0-1.81.01.6-1.60.6
Pavlov. Cond. magazine entry number7.28.910.23.03.0-3.1-3.1-3.13.2-3.23.2-3.2-3.1-3.13.12.8-3.13.1-2.4-2.92.9-2.0
Pavlov. Cond. intertrial magazine entries0.40.50.60.70.6-0.7-0.7-0.60.8-0.80.8-0.8-0.7-0.70.70.6-0.80.7-0.4-0.60.6-0.4
Pavlov. Cond. lever-magazine prob. diff.5.66.98.1-2.6-2.62.72.72.7-2.92.9-2.92.92.72.7-2.8-2.42.8-2.81.82.7-2.71.5
Pavlov. Cond. response bias6.68.19.6-2.9-2.92.92.92.9-3.13.1-3.13.12.92.9-3.0-2.63.0-2.92.02.7-2.71.9
Pavlov. Cond. lever latency0.50.71.4-1.0-1.00.90.91.0-0.60.6-0.60.60.90.8-0.8-0.80.7-0.81.20.4-0.41.1
Pavlov. Cond. magazine entry latency0.10.10.3-0.1-0.10.10.10.1-0.50.5-0.50.50.20.2-0.3-0.10.4-0.3-0.60.5-0.5-0.4
Pavlov. Cond. change in total contacts2.43.34.72.22.1-2.0-2.0-2.11.7-1.71.7-1.7-1.9-1.91.91.6-1.81.8-2.1-1.01.0-2.0
Pavlov. Cond. index score0.20.21.30.60.6-0.5-0.5-0.50.1-0.10.1-0.1-0.4-0.40.40.5-0.20.3-1.1-0.00.0-0.9
Pavlov. Cond. latency score0.20.21.20.50.5-0.5-0.5-0.50.1-0.10.1-0.1-0.3-0.30.30.5-0.10.2-1.10.0-0.0-0.9
Pavlov. Cond. lever contacts1.01.42.11.41.4-1.3-1.3-1.31.0-1.01.0-1.0-1.3-1.21.21.1-1.21.2-1.5-0.60.6-1.4
Pavlov. Cond. magazine entry number0.30.30.70.40.4-0.4-0.4-0.40.8-0.80.8-0.8-0.5-0.50.50.4-0.60.50.2-0.80.80.0
Pavlov. Cond. intertrial magazine entries0.40.61.9-0.8-0.80.80.80.8-0.50.5-0.50.50.80.7-0.7-0.90.5-0.71.40.7-0.70.8
Pavlov. Cond. lever-magazine prob. diff.0.20.21.40.60.6-0.5-0.5-0.50.1-0.10.1-0.1-0.4-0.40.30.5-0.20.3-1.2-0.00.0-0.8
Pavlov. Cond. response bias0.20.21.00.60.6-0.5-0.5-0.50.1-0.10.1-0.1-0.4-0.40.40.3-0.20.3-1.00.2-0.2-0.9
Time in closed arm before self-admin1.61.82.41.31.4-1.4-1.1-1.21.4-1.41.4-1.4-1.4-1.51.51.3-1.51.5-1.2-1.21.2-1.0
Time in closed arm after self-admin0.10.10.20.10.2-0.1-0.2-0.50.1-0.10.1-0.1-0.2-0.30.30.2-0.20.3-0.2-0.40.4-0.1
Time in open arm before self-admin1.11.21.7-1.1-1.01.21.10.7-1.21.2-1.21.21.21.1-1.2-1.31.2-1.20.90.8-0.81.0
Time in open arm after self-admin0.40.41.3-0.4-0.60.40.91.1-0.40.4-0.40.40.40.7-0.5-0.70.4-0.50.91.1-1.1-0.1
Bone: periosteal estimation0.00.10.50.20.2-0.2-0.2-0.30.1-0.10.1-0.1-0.2-0.20.20.6-0.10.2-0.4-0.70.7-0.1
Bone: periosteal perimeter1.01.62.1-1.3-1.31.41.41.3-1.41.4-1.41.41.41.3-1.4-0.91.4-1.40.90.6-0.61.1
Bone: post-yield work0.10.20.90.30.3-0.2-0.2-0.30.2-0.20.2-0.2-0.3-0.30.30.6-0.20.3-0.4-1.01.00.0
Progressive ratio test 1 active lever presses0.00.00.1-0.2-0.00.00.0-0.1-0.20.2-0.20.2-0.2-0.00.20.0-0.20.30.1-0.30.30.0
Progressive ratio test 1 breakpoint0.00.00.1-0.2-0.10.10.1-0.1-0.20.2-0.20.2-0.10.10.1-0.0-0.10.20.2-0.40.40.1
Progressive ratio test 1 inactive lever presses0.40.51.4-0.7-0.70.60.71.0-0.70.7-0.70.70.70.5-0.6-0.70.6-0.70.30.5-0.51.2
Progressive ratio test 2 active lever presses0.80.91.2-1.1-1.00.80.80.9-1.11.1-1.11.10.90.9-0.8-1.10.9-0.80.80.9-0.90.8
Progressive ratio test 2 breakpoint0.70.81.1-1.0-0.90.70.80.7-1.01.0-1.01.00.80.8-0.8-1.00.8-0.70.70.8-0.80.7
Progressive ratio test 2 inactive lever presses1.82.13.1-1.6-1.51.11.21.5-1.61.6-1.61.61.51.3-1.3-1.51.5-1.50.81.3-1.31.8
Incentive Sensitization - Responses1.71.82.3-1.4-1.31.21.31.2-1.41.4-1.41.41.41.3-1.4-1.51.4-1.50.91.3-1.31.2
Incentive Sensitization - Breakpoint1.71.72.2-1.4-1.31.21.31.2-1.41.4-1.41.41.41.2-1.4-1.51.4-1.40.91.3-1.31.2
Sum of active levers in priming session hrs 5-60.30.30.70.60.6-0.8-0.8-0.30.7-0.70.7-0.7-0.6-0.50.60.3-0.70.6-0.2-0.20.2-0.4
Progressive ratio3.74.36.92.02.0-2.6-2.3-2.22.0-2.02.0-2.0-2.2-2.12.32.0-2.22.3-1.6-2.02.0-1.5
Food seeking constrained by brief footshock0.60.71.1-1.0-0.80.60.80.3-1.01.0-1.01.00.80.8-0.8-1.00.9-0.80.70.7-0.70.5
Seeking ratio, punishment vs. effort5.26.48.2-2.6-2.52.92.72.3-2.62.6-2.62.62.72.5-2.7-2.52.7-2.71.92.2-2.22.0
Retroperitoneal fat weight0.72.44.01.41.5-1.5-1.5-1.71.5-1.51.5-1.5-1.5-1.31.41.9-1.41.5-1.4-2.02.0-1.5
Reaction time number correct0.30.41.6-0.7-0.60.50.60.9-0.60.6-0.60.60.60.5-0.6-0.60.5-0.60.50.0-0.01.3
Reaction time mean minus median0.00.00.10.20.1-0.00.1-0.10.2-0.20.2-0.2-0.2-0.20.10.0-0.20.1-0.30.0-0.0-0.2
Reaction time mean minus median AUC0.20.20.30.50.4-0.4-0.3-0.60.5-0.50.5-0.5-0.6-0.50.50.3-0.60.5-0.3-0.40.4-0.3
Reaction time num false alarms0.30.41.2-0.7-0.70.50.60.7-0.50.5-0.50.50.60.6-0.6-0.90.5-0.61.10.7-0.70.6
Reaction time num false alarms AUC0.10.10.8-0.4-0.40.20.30.4-0.10.1-0.10.10.30.3-0.3-0.60.1-0.30.90.3-0.30.4
Reaction time trials correct on left0.30.41.6-0.7-0.60.50.60.9-0.60.6-0.60.60.60.5-0.6-0.60.5-0.60.50.0-0.01.3
Reaction time trials on left0.30.51.8-0.7-0.60.60.60.9-0.60.6-0.60.60.70.5-0.6-0.70.6-0.60.60.1-0.11.3
Reaction time mean0.00.00.0-0.1-0.00.10.20.00.0-0.00.0-0.0-0.1-0.10.1-0.1-0.20.10.00.0-0.00.1
Reaction time mean AUC0.00.00.1-0.2-0.10.20.20.0-0.00.0-0.00.0-0.0-0.00.0-0.1-0.10.10.2-0.10.10.2
Median of all reaction times0.00.00.0-0.1-0.00.10.20.10.0-0.00.0-0.0-0.0-0.10.1-0.1-0.10.10.20.0-0.00.2
Reaction time omissions0.60.82.9-1.0-0.91.11.11.1-0.40.4-0.40.40.80.6-0.7-1.20.5-0.71.50.8-0.81.7
Reaction time false alarm rate0.10.10.5-0.2-0.30.20.20.1-0.00.0-0.00.00.20.3-0.2-0.40.1-0.20.70.5-0.5-0.1
Reaction time premature initiation rate1.72.33.41.61.5-1.3-1.4-1.21.8-1.81.8-1.8-1.5-1.51.31.5-1.51.3-1.3-1.41.4-1.0
Reaction time premature initiations0.81.11.71.11.1-0.9-1.0-0.61.3-1.31.3-1.3-1.0-1.10.91.1-1.00.8-1.0-1.21.2-0.3
Std. dev. reaction times0.10.10.20.10.2-0.2-0.0-0.30.3-0.30.3-0.3-0.4-0.30.40.0-0.50.4-0.0-0.10.1-0.2
Reaction time trials completed0.30.51.8-0.7-0.60.60.60.9-0.60.6-0.60.60.70.5-0.6-0.70.6-0.60.60.1-0.11.3
Reaction time trials AUC0.40.62.0-0.8-0.70.60.71.0-0.70.7-0.70.70.70.6-0.7-0.80.6-0.70.70.2-0.21.4
Run reversals in cocaine runway, females1.81.72.3-1.5-1.51.41.31.2-1.41.4-1.41.41.41.4-1.4-1.11.5-1.40.90.8-0.81.2
Run reversals in cocaine runway, males0.30.30.80.90.6-0.40.10.30.8-0.80.8-0.8-0.4-0.50.20.1-0.40.1-0.50.4-0.40.0
Latency to leave start box in cocaine runway0.20.20.50.70.5-0.4-0.5-0.00.5-0.50.5-0.5-0.4-0.50.30.1-0.40.3-0.40.4-0.4-0.3
Latency to leave start box in cocaine runway, F0.80.91.91.41.2-0.9-1.0-0.51.2-1.21.2-1.2-0.9-1.20.90.6-1.00.7-1.2-0.10.1-0.4
Latency to leave start box in cocaine runway, M0.30.30.6-0.6-0.70.30.30.6-0.60.6-0.60.60.50.8-0.6-0.50.6-0.50.70.6-0.60.0
Std. dev. time between licks in bursts3.13.75.3-1.9-2.01.91.91.9-2.32.3-2.32.32.01.8-1.9-1.62.0-2.01.01.2-1.22.2
Total sessions with >9 infusions0.20.20.8-0.3-0.1-0.1-0.5-0.3-0.30.3-0.30.30.1-0.1-0.0-0.00.1-0.1-0.4-0.80.80.9
Short access day 1 total inactive lever presses2.42.74.1-2.0-1.81.21.21.5-2.02.0-2.02.01.71.6-1.6-1.61.8-1.61.11.1-1.11.6
Short access day 10 total inactive lever presses0.10.10.60.0-0.10.30.30.40.0-0.00.0-0.00.40.1-0.3-0.30.3-0.5-0.20.4-0.40.8
Short access day 1 total infusions0.60.71.0-1.0-0.90.80.40.7-1.01.0-1.01.00.90.8-0.8-0.80.9-0.80.60.3-0.31.0
Short access day 10 total infusions0.10.10.3-0.3-0.0-0.1-0.3-0.5-0.30.3-0.30.3-0.1-0.00.20.1-0.10.3-0.0-0.50.5-0.0
Short access total infusions0.30.30.6-0.8-0.70.50.30.3-0.80.8-0.80.80.50.6-0.5-0.60.5-0.40.50.0-0.00.6
Short access day 1 locomotion0.10.10.7-0.3-0.1-0.4-0.9-0.4-0.30.3-0.30.30.00.00.0-0.20.00.10.1-0.60.60.6
Short access day 10 total locomotion0.10.10.50.10.2-0.5-0.7-0.50.1-0.10.1-0.1-0.4-0.20.40.3-0.40.50.1-0.60.6-0.3
Short access total locomotion0.10.10.4-0.2-0.0-0.3-0.6-0.2-0.20.2-0.20.2-0.2-0.00.1-0.3-0.20.30.3-0.30.30.3
One hour access (0.3 mA shock)0.10.10.2-0.5-0.30.40.20.3-0.50.5-0.50.50.10.2-0.0-0.50.10.00.30.1-0.10.5
Compulsive drug intake0.00.00.20.0-0.00.20.10.00.0-0.00.0-0.0-0.00.2-0.1-0.1-0.00.00.40.0-0.0-0.1
One hour access (shock baseline)0.10.10.2-0.4-0.30.20.20.4-0.40.4-0.40.40.10.00.0-0.40.1-0.00.00.4-0.40.4
Social response proportion0.20.30.70.50.5-0.1-0.1-0.10.8-0.80.8-0.8-0.5-0.50.40.3-0.60.4-0.1-0.40.40.2
Social responses0.40.50.60.60.7-0.5-0.6-0.70.8-0.80.8-0.8-0.7-0.60.60.7-0.70.7-0.5-0.80.8-0.6
Social time0.81.14.0-0.8-0.91.41.51.5-0.60.6-0.60.61.10.7-1.1-0.91.1-1.30.00.5-0.52.0
Soleus weight4.011.613.23.63.6-3.6-3.6-3.63.2-3.23.2-3.2-3.5-3.53.43.4-3.33.4-3.6-3.43.4-2.8
Bone: stiffness0.10.20.40.40.4-0.4-0.4-0.40.5-0.50.5-0.5-0.4-0.40.40.5-0.40.4-0.1-0.60.6-0.4
Tibialis anterior weight0.00.10.40.30.2-0.3-0.3-0.30.0-0.00.0-0.0-0.2-0.30.20.3-0.10.2-0.6-0.40.4-0.1
Time to tail flick, vehicle, before self-admin2.02.12.91.51.4-1.6-1.7-1.71.3-1.31.3-1.3-1.5-1.51.51.4-1.51.6-1.2-1.61.6-0.7
Time to tail flick, vehicle, after self-admin0.30.30.91.00.7-0.0-0.2-0.10.8-0.80.8-0.8-0.5-0.70.50.6-0.50.4-0.7-0.20.2-0.2
Time to tail flick, test, before self-admin0.10.10.30.40.30.10.1-0.20.3-0.30.3-0.3-0.20.0-0.00.0-0.20.00.3-0.50.50.1
Time to tail flick, test, after self-admin0.10.10.2-0.5-0.40.1-0.10.2-0.50.5-0.50.50.40.3-0.3-0.20.4-0.3-0.00.2-0.20.5
Delta time to tail flick, vehicle, before/after SA0.80.81.9-0.6-0.71.41.21.2-0.60.6-0.60.60.90.8-0.9-0.70.9-1.00.41.1-1.10.5
Delta time to tail flick, test, before/after SA0.20.20.6-0.8-0.5-0.1-0.30.1-0.60.6-0.60.60.40.3-0.2-0.00.4-0.1-0.10.3-0.30.1
Tibia length7.521.127.44.74.8-4.8-4.8-4.94.2-4.24.2-4.2-4.6-4.54.55.1-4.24.4-5.2-4.84.8-4.4
Ambulatory time before self-admin0.10.10.3-0.2-0.10.4-0.2-0.5-0.20.2-0.20.20.2-0.00.00.20.2-0.0-0.3-0.50.50.4
Ambulatory time after self-admin0.10.10.5-0.0-0.10.70.60.6-0.00.0-0.00.00.20.2-0.2-0.40.1-0.30.20.6-0.6-0.0
Bone: tissue strength3.13.03.51.81.8-1.9-1.9-1.81.7-1.71.7-1.7-1.6-1.81.71.8-1.61.6-1.8-1.41.4-1.6
Total heroin consumption1.01.21.71.21.2-1.0-1.2-0.71.3-1.31.3-1.3-1.1-1.21.01.0-1.10.9-1.2-0.70.7-0.7
Bone: trabecular number0.50.81.3-0.9-0.90.90.90.8-1.01.0-1.01.00.81.0-0.9-0.90.9-0.80.91.2-1.2-0.1
Bone: trabecular spacing1.31.62.11.31.3-1.3-1.3-1.21.4-1.41.4-1.4-1.2-1.41.21.3-1.21.1-1.3-1.41.4-0.5
Bone: trabecular thickness0.10.11.50.20.2-0.2-0.2-0.30.1-0.10.1-0.1-0.20.00.10.5-0.10.2-0.3-0.10.1-1.2
Bone: trabecular tissue density0.20.30.60.60.6-0.5-0.5-0.40.6-0.60.6-0.6-0.6-0.40.50.2-0.50.5-0.20.0-0.0-0.8
Water consumed over 24 hours0.10.10.40.00.00.00.00.0-0.20.2-0.20.20.1-0.1-0.00.20.2-0.1-0.6-0.50.50.6
Number of responses in last shaping day0.50.50.8-0.9-0.70.40.50.3-0.90.9-0.90.90.80.7-0.7-0.60.8-0.70.40.5-0.50.6