Hub : Genes

Tcf19

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Tcf19 0.21 0.08 0.0e+00 0.12 0.19 0.18 0.17 3.7e-11 1.4e-17 2.2e-16 2.0e-15
2 IL gene expression Tcf19 0.33 0.12 2.8e-06 0.18 0.23 0.21 0.22 3.5e-05 3.9e-06 9.7e-06 5.4e-06
3 PL gene expression Tcf19 0.31 0.09 0.0e+00 0.16 0.32 0.32 0.32 7.6e-17 2.1e-35 1.2e-35 7.4e-36
4 Eye mRNA stability Tcf19 0.39 0.18 5.0e-03 0.03 0.06 0.05 0.05 1.1e-01 4.4e-02 5.6e-02 6.8e-02
5 OFC gene expression Tcf19 0.29 0.13 1.1e-04 0.15 0.13 0.09 0.14 1.7e-04 4.7e-04 4.7e-03 3.8e-04
6 BLA gene expression Tcf19 0.25 0.09 1.8e-12 0.2 0.21 0.2 0.21 3.3e-11 3.0e-11 6.9e-11 2.4e-11
7 NAcc gene expression Tcf19 0.07 0.04 6.4e-06 0.04 0.04 0.03 0.03 4.1e-05 1.2e-05 1.9e-04 1.8e-04
8 Adipose gene expression Tcf19 0.09 0.05 3.0e-13 0.11 0.11 0.1 0.11 1.5e-12 1.7e-12 1.7e-11 4.2e-12
9 Liver gene expression Tcf19 0.1 0.05 9.0e-08 0.05 0.04 0.05 0.05 2.9e-06 1.5e-05 3.1e-06 1.5e-06
10 pVTA gene expression Tcf19 0.06 0.04 7.2e-03 0.03 0.01 0.03 0.02 2.0e-02 1.1e-01 1.8e-02 5.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.93.35.0-2.1-2.2-2.2-0.01.7-1.9-2.2-1.0-1.42.0
Area under the delay curve1.21.23.00.40.90.61.0-1.60.91.21.41.7-0.8
BMI with tail1.23.87.51.01.80.52.4-2.72.12.02.21.4-2.4
BMI without tail2.55.39.01.82.61.41.8-3.02.52.62.11.7-2.8
Body weight5.121.333.84.05.13.43.1-5.85.55.14.13.8-5.2
Weight adjusted by age4.24.77.72.32.62.10.8-1.92.32.61.32.2-2.8
Bone surface0.20.31.00.60.60.5-0.2-0.50.60.50.01.00.3
Bone volume0.10.10.3-0.3-0.1-0.40.5-0.30.2-0.10.30.60.5
Breakpoint value in progressive ratio session0.70.81.7-0.4-0.8-0.4-1.01.2-1.3-0.7-1.1-0.40.9
Number of licking bursts0.50.62.10.80.31.0-1.50.4-0.20.3-1.1-0.00.6
Context. condit. distance diff. score3.94.712.00.3-0.90.4-3.52.6-2.0-1.3-3.4-2.32.2
Locomotion velocity, session 10.10.10.70.2-0.00.3-0.80.4-0.2-0.1-0.6-0.2-0.0
Locomotion distance, session 10.91.12.2-1.5-1.4-1.40.30.8-1.0-1.2-0.1-1.30.6
Locomotion velocity, session 20.10.10.30.20.10.5-0.60.00.20.1-0.2-0.10.3
Locomotion distance, session 20.50.71.4-0.8-0.9-0.7-0.40.8-0.8-0.8-0.6-1.20.9
Locomotion velocity, session 30.30.41.4-0.7-0.4-0.70.9-0.1-0.1-0.30.6-1.2-0.5
Locomotion distance, session 31.92.14.4-1.3-1.5-1.2-0.61.4-1.4-1.6-1.4-2.11.5
Stereotopy head waving bouts, day 32.12.43.81.91.91.9-0.1-1.51.71.90.81.5-1.1
Stereotopy head waving duration, day 31.61.92.91.61.71.60.1-1.31.41.70.91.4-1.5
Locomotion velocity, session 74.34.78.0-1.5-2.1-1.4-1.52.4-2.2-2.3-2.2-2.82.6
Locomotion distance, session 74.75.99.3-2.2-2.6-1.9-1.32.5-2.6-2.6-2.0-3.13.0
Stereotopy head waving bouts, day 71.51.73.30.61.10.70.9-1.71.61.21.81.6-1.0
Stereotopy head waving duration, day 72.12.64.41.11.51.11.0-2.02.11.61.91.9-1.5
Locomotion velocity, session 81.92.25.82.21.52.3-2.4-0.00.81.2-1.30.60.2
Locomotion distance, session 82.53.78.2-0.1-1.10.1-2.82.1-1.7-1.2-2.9-2.32.3
Degree of sensitization distance0.30.31.40.60.20.6-1.20.6-0.40.2-0.70.10.5
Degree of sensitization stereotypy0.90.92.30.20.60.30.8-1.41.30.71.51.4-0.4
Conditioned locomotion0.70.91.51.21.21.20.0-1.01.01.2-0.20.4-0.7
Cocaine response after cond. corrected0.40.40.8-0.5-0.7-0.4-0.50.8-0.9-0.5-0.6-0.50.7
Cocaine response after cond. not corrected0.50.61.21.10.91.1-0.6-0.40.60.9-0.11.0-0.3
Cocaine response before conditioning5.46.59.52.73.02.60.5-2.73.02.91.53.1-2.3
Saline control response0.91.25.0-0.40.3-0.72.2-1.10.80.21.70.1-1.2
Bone: connectivity density2.23.55.1-1.5-2.0-1.8-1.12.3-2.2-2.2-1.9-1.62.0
Bone: cortical apparent density0.60.83.8-1.0-0.5-1.01.9-0.50.0-0.31.3-0.2-0.6
Bone: cortical area1.32.04.10.91.40.91.2-2.01.81.61.41.6-0.7
Bone: cortical porosity0.30.41.0-0.20.2-0.10.9-0.70.50.31.00.8-0.5
Bone: cortical porosity0.60.71.50.70.90.80.2-0.90.90.90.51.2-0.6
Bone: cortical thickness1.82.910.4-1.00.2-1.03.2-2.11.40.72.81.1-0.8
Bone: cortical thickness1.11.24.5-1.3-0.6-1.52.1-0.6-0.0-0.41.5-0.5-0.7
Bone: cortical tissue density0.50.73.1-0.9-0.4-0.81.8-0.50.0-0.21.1-0.2-0.7
Condit. Reinf. active minus inactive responses0.70.81.4-0.6-0.8-0.7-0.71.2-1.1-1.0-1.1-0.80.8
Condit. Reinf. active-inactive response ratio0.10.10.3-0.5-0.3-0.60.50.2-0.3-0.30.20.2-0.3
Condit. Reinf. active responses1.31.62.7-1.0-1.3-1.1-0.61.4-1.4-1.4-1.5-1.61.1
Condit. Reinf. inactive responses2.83.47.1-1.9-2.0-1.8-0.31.6-1.8-2.1-1.3-2.71.8
Incentive salience index mean1.21.54.50.0-0.60.0-1.81.4-1.1-0.8-2.1-0.81.6
Condit. Reinf. lever presses2.12.88.50.3-0.60.4-2.71.7-1.3-0.8-2.9-1.02.3
Condit. Reinf. active minus inactive responses1.21.52.11.21.41.10.6-1.51.41.40.81.2-1.4
Condit. Reinf. active-inactive response ratio3.03.14.41.82.01.80.4-2.02.02.11.02.0-1.7
Condit. Reinf. active responses0.00.00.20.20.20.1-0.0-0.0-0.00.1-0.2-0.2-0.5
Condit. Reinf. inactive responses1.31.63.0-1.0-1.2-1.2-0.41.6-1.6-1.5-1.2-1.70.6
Condit. Reinf. lever presses0.30.40.7-0.5-0.6-0.6-0.30.8-0.8-0.7-0.7-0.80.2
Condit. Reinf. lever reinforcers received0.00.10.30.20.10.1-0.20.1-0.20.0-0.5-0.1-0.4
Conditioned reinforcement - actives0.30.30.90.40.50.40.4-0.30.60.70.30.9-0.6
Conditioned reinforcement - inactives0.50.61.7-0.10.4-0.21.3-1.00.80.50.80.9-0.6
Conditioned locomotion0.10.10.20.50.40.3-0.20.20.10.4-0.30.4-0.1
Patch foraging indifference point 0 sec0.50.93.6-0.7-0.2-1.01.9-0.40.3-0.11.2-0.3-1.3
Patch foraging indifference point AUC1.41.63.80.91.31.00.8-1.91.91.50.91.0-0.7
Delay disc. indifference point, 0s delay0.70.72.80.90.81.1-0.3-0.60.61.0-0.01.7-0.1
Delay disc. indifference point, 16s delay0.90.93.2-0.9-0.2-0.71.8-1.3-0.10.31.60.7-0.4
Delay disc. indifference point, 2s delay2.32.65.81.51.71.60.3-1.51.72.01.02.4-1.5
Delay disc. indifference point, 24s delay0.40.41.0-0.00.30.00.8-0.80.20.51.00.7-1.0
Delay disc. indifference point, 4s delay2.32.43.81.51.81.50.5-1.81.51.91.12.0-1.4
Delay disc. indifference point, 8s delay0.10.10.4-0.00.20.10.4-0.60.10.40.50.5-0.1
Indifference point function ln k0.30.41.50.3-0.00.6-1.20.8-0.4-0.1-0.90.40.5
Indifference point function log k0.30.41.50.3-0.00.6-1.20.8-0.4-0.1-0.90.40.5
Patch foraging total patch changes 0 sec0.71.14.8-0.9-0.2-1.12.2-0.60.3-0.11.3-0.3-1.3
Patch foraging total patch changes 12 sec0.70.93.7-0.8-0.1-0.81.9-0.90.60.11.20.3-1.0
Patch foraging total patch changes 18 sec1.72.25.3-2.0-1.4-2.22.3-0.1-0.3-1.21.1-1.7-0.1
Patch foraging total patch changes 24 sec2.32.86.5-2.5-2.1-2.61.61.0-1.2-1.80.6-1.20.8
Patch foraging total patch changes 6 sec0.81.25.1-1.2-0.5-1.32.3-0.50.3-0.21.2-0.5-1.0
Patch foraging time to switch 0 sec0.60.92.0-1.2-1.1-1.40.80.9-0.9-1.00.5-0.8-0.2
Patch foraging water rate 0 sec0.30.50.90.40.70.60.6-0.90.80.90.50.6-0.6
Patch foraging water rate 12 sec0.40.61.3-1.1-0.9-0.90.60.4-0.6-0.80.3-0.70.6
Patch foraging water rate 18 sec0.10.10.30.40.50.40.4-0.50.20.4-0.2-0.1-0.1
Patch foraging water rate 24 sec0.71.02.60.30.90.31.2-1.61.11.01.40.8-0.6
Patch foraging water rate 6 sec0.10.20.4-0.6-0.4-0.50.60.0-0.3-0.30.3-0.40.1
Seeking ratio, delayed vs. immediate footshock0.40.40.80.50.70.30.5-0.70.80.60.50.8-0.9
Distance traveled before self-admin0.30.30.60.80.50.8-0.7-0.00.60.3-0.8-0.00.2
Distance traveled after self-admin0.70.81.51.21.11.0-0.2-0.80.60.90.40.8-1.2
Extensor digitorum longus weight0.20.92.01.41.11.4-0.9-0.30.71.0-0.70.6-0.3
Bone: elastic displacement0.30.41.0-0.9-0.5-0.81.0-0.20.1-0.40.80.1-0.4
Bone: elastic work1.11.52.90.30.80.21.4-1.61.41.01.71.7-0.8
Bone: endosteal estimation4.810.420.14.54.14.3-1.4-2.43.23.70.13.1-2.6
Bone: endosteal perimeter2.14.510.63.32.53.2-2.6-0.51.32.0-1.51.5-0.7
Epididymis fat weight3.27.426.9-3.0-1.4-3.15.2-1.6-0.2-0.64.4-0.6-2.0
Delta time in closed arm before/after self-admin0.50.51.00.80.70.80.1-0.50.30.90.11.0-1.0
Delta time in open arm before/after self-admin0.20.20.5-0.4-0.3-0.60.5-0.1-0.3-0.50.2-0.70.2
Diff in mean of infusions in LGA sessions3.43.86.4-1.8-2.2-1.5-1.12.2-2.0-2.0-1.9-1.72.5
Delay discount exponential model param1.21.22.9-0.4-0.9-0.5-1.01.5-0.8-1.2-1.4-1.70.9
Extinction: sum of active levers before priming0.40.41.4-0.4-0.6-0.2-0.50.9-1.2-0.4-0.7-0.00.5
Active lever presses in extinction session 60.20.20.4-0.6-0.5-0.60.50.1-0.5-0.40.7-0.2-0.3
Bone: final force3.65.912.10.91.90.82.9-3.32.82.33.52.3-1.8
Bone: final moment3.35.310.30.91.90.82.8-3.22.72.23.22.1-1.7
Food consumed during 24 hour testing period1.01.22.31.51.41.5-0.3-1.11.31.30.20.4-0.8
Glucose2.53.712.52.71.52.7-3.50.50.21.2-2.31.00.6
Heart weight0.50.72.10.80.80.6-0.1-0.40.50.90.41.5-1.2
Delay discount hyperbolic model param1.41.43.5-0.6-1.0-0.7-0.91.6-1.0-1.3-1.3-1.91.0
Intermittent access intake day 1-15 change0.30.31.0-0.30.1-0.40.9-1.00.7-0.00.4-0.60.1
Intermittent access intake escalation0.20.10.50.20.30.10.2-0.70.60.0-0.0-0.60.3
Intermittent access intake escalation 20.70.71.71.00.71.1-1.3-0.40.60.3-1.0-0.40.9
Intermitt. access day 1 inactive lever presses1.01.12.41.41.21.4-0.7-0.50.71.30.11.5-0.8
Intermitt. access day 15 inactive lever presses1.82.03.40.91.40.91.2-1.91.81.51.31.4-1.6
Intermitt. access escalation Index1.91.73.6-0.8-1.3-0.8-1.41.9-1.7-1.4-1.1-0.61.3
Intermittent access day 1 total infusions0.60.71.2-0.9-1.0-0.8-0.31.1-0.9-0.9-0.6-0.51.0
Intermittent access day 15 total infusions0.40.40.8-0.7-0.6-0.70.20.5-0.4-0.7-0.5-0.90.8
Intermittent access terminal intake (last 3 days)0.00.00.1-0.2-0.0-0.20.3-0.00.10.0-0.00.00.0
Intermittent access total infusions0.10.10.3-0.5-0.4-0.50.30.4-0.2-0.4-0.3-0.40.3
Intermittent access day 1 locomotion0.20.20.60.2-0.10.0-0.60.8-0.4-0.3-0.8-0.40.3
Intermittent access day 15 total locomotion0.50.51.21.01.10.70.2-0.81.00.8-0.10.3-0.2
Intermittent access total locomotion0.20.30.60.70.80.40.2-0.70.80.4-0.2-0.30.1
Intermittent access standard deviation1.61.73.30.41.00.21.8-1.81.31.11.70.7-1.7
Left kidney weight3.18.613.42.13.01.92.3-3.63.73.03.02.8-3.3
Right kidney weight2.77.611.72.73.22.31.5-3.43.33.12.22.3-2.9
Cocaine induced anxiety1.72.05.20.0-0.7-0.1-2.01.7-1.1-1.1-2.3-1.51.7
Post-drug Anxiety0.40.51.80.5-0.00.4-1.30.9-0.5-0.2-1.2-0.40.3
Baseline Anxiety0.30.41.5-0.00.10.10.5-0.3-0.10.50.81.0-1.2
Tail length5.015.224.74.75.04.5-0.0-4.24.54.71.53.5-3.4
Length with tail4.315.623.34.24.84.10.9-4.54.84.52.53.8-3.7
Length without tail3.06.510.22.42.82.41.0-3.03.22.82.02.8-2.3
Times rat made contact with spout2.63.05.4-2.3-2.1-2.30.71.4-1.7-2.1-0.2-1.91.2
Lifetime Intake0.00.00.1-0.2-0.2-0.20.10.4-0.2-0.1-0.30.10.2
Liver weight, left0.81.33.01.71.61.5-0.4-0.91.31.2-0.20.5-1.0
Liver weight, right4.26.910.43.23.23.2-0.7-2.63.13.00.82.9-1.8
Locomotor activity1.92.95.82.42.32.3-0.7-1.32.21.7-0.21.2-1.3
Locomotor testing distance0.40.71.51.21.11.1-0.4-0.41.10.9-0.10.4-0.9
Locomotor testing rearing0.81.32.51.61.51.3-0.3-0.91.41.20.11.0-1.2
Locomotion in novel chamber0.40.40.90.40.70.40.5-1.00.90.70.70.7-0.5
Locomotion in novel chamber post-restriction0.50.71.50.30.60.11.0-1.00.60.71.10.7-1.2
Fecal boli incidents, locomotor time 10.40.41.0-0.4-0.6-0.6-0.41.0-0.8-0.8-0.6-0.80.2
Change in fecal boli incidents, locomotor task1.41.33.31.11.11.4-0.3-0.91.21.50.51.8-0.9
Time >=10cm from walls, locomotor time 11.71.73.61.91.71.7-0.6-0.91.21.50.21.1-1.3
Bouts of movement, locomotor time 11.11.22.5-0.2-0.6-0.1-1.31.0-1.1-1.0-1.6-1.31.5
Total resting periods, locomotor time 10.60.71.80.1-0.30.2-1.20.6-0.8-0.5-1.3-1.01.2
Rest time, locomotor task time 10.40.41.11.00.80.8-0.8-0.30.50.4-0.6-0.1-0.2
Distance moved, locomotor task time 10.40.41.2-0.10.2-0.11.0-0.70.50.41.10.7-0.6
Vertical activity count, locomotor time 10.30.31.0-0.30.0-0.41.0-0.40.30.11.00.4-0.5
Time >=10cm from walls, locomotor time 21.01.02.11.41.11.1-0.7-0.10.71.1-0.11.2-1.4
Bouts of movement, locomotor time 20.70.81.51.21.21.0-0.4-0.81.20.70.00.9-0.5
Total resting periods, locomotor time 20.90.92.01.41.21.3-0.9-0.61.10.7-0.41.0-0.3
Rest time, locomotor task time 21.21.44.21.71.11.7-2.0-0.00.50.6-1.5-0.10.5
Distance moved, locomotor task time 20.60.72.7-0.7-0.2-0.71.6-0.50.20.11.40.4-0.7
Vertical activity count, locomotor time 20.20.20.8-0.5-0.3-0.60.9-0.0-0.3-0.00.80.0-0.6
Light reinforcement 10.20.41.5-0.5-0.3-0.71.0-0.20.0-0.01.20.4-0.5
Light reinforcement 20.50.71.20.91.00.80.3-1.10.90.90.80.7-0.6
Bone: marrow area4.810.320.04.54.14.3-1.3-2.43.13.70.13.1-2.7
Bone: maximum diameter1.42.65.62.31.92.4-1.3-1.11.51.8-0.51.6-0.1
Bone: maximum force3.05.210.01.12.00.92.5-3.22.72.33.02.1-1.7
Bone: maximum moment2.74.79.41.22.01.02.3-3.12.72.22.71.9-1.7
Mean time between licks in bursts1.31.84.91.91.21.9-2.20.00.50.9-1.50.90.4
Mean num. licks in bursts1.41.74.3-1.8-1.3-2.11.70.3-0.7-1.31.0-1.0-0.0
Cd content in liver0.40.51.9-0.6-0.2-0.81.4-0.80.2-0.10.9-0.4-0.2
Co content in liver1.21.43.6-0.10.4-0.21.9-1.20.70.71.80.8-1.9
Cu content in liver4.04.98.4-2.8-2.9-2.90.22.3-2.4-2.8-0.5-1.61.5
Fe content in liver0.60.72.3-0.5-0.1-0.71.4-0.60.5-0.01.50.2-1.0
K content in liver0.20.20.5-0.2-0.40.1-0.60.3-0.6-0.2-0.60.10.7
Mg content in liver1.92.06.70.5-0.30.9-2.61.4-1.3-0.3-2.4-0.11.5
Mn content in liver2.62.99.62.11.12.3-3.10.9-0.10.9-2.50.80.3
Na content in liver0.20.21.1-0.5-0.3-0.10.2-0.10.1-0.00.4-0.31.1
Rb content in liver0.60.71.5-0.4-0.8-0.3-0.81.0-1.2-0.7-1.0-0.71.0
Se content in liver1.61.97.31.40.61.7-2.70.7-0.10.4-2.00.81.2
Sr content in liver1.11.01.91.31.21.2-0.2-0.71.01.20.41.4-0.6
Zn content in liver0.30.31.90.50.30.6-0.50.30.10.5-0.11.4-0.4
Bone: minimum diameter2.03.78.02.82.42.8-1.4-1.21.72.2-0.62.0-0.7
Time in familiar zone, hab. session 15.24.87.7-2.7-2.6-2.80.52.0-2.3-2.7-0.5-2.61.6
Time in novel zone, hab. session 13.43.35.62.42.22.3-0.5-1.41.72.10.12.1-1.7
Total zone transitions, hab. session 10.50.81.5-0.7-0.9-0.6-0.61.0-1.1-0.8-0.9-1.20.5
Total locomotion distance, hab. session 10.50.81.2-0.8-1.0-0.7-0.41.0-1.1-0.8-0.9-0.91.0
Locomotion velocity, hab. session 10.30.40.7-0.7-0.8-0.7-0.10.7-0.8-0.6-0.5-0.70.7
Time in familiar zone, hab. session 20.60.61.1-1.0-0.9-1.00.40.7-0.8-0.90.5-0.90.4
Time in novel zone, hab. session 20.40.41.00.60.70.50.2-0.70.70.6-0.10.5-1.0
Total zone transitions, hab. session 20.10.20.6-0.5-0.4-0.40.30.1-0.3-0.20.5-0.80.0
Total locomotion distance, hab. session 21.21.52.7-1.2-1.4-1.1-0.51.3-1.5-1.3-0.8-1.71.2
Locomotion velocity, hab. session 21.21.62.3-1.2-1.4-1.0-0.71.4-1.5-1.2-0.9-1.51.4
Novel to familiar place preference ratio0.10.10.2-0.5-0.3-0.30.30.0-0.2-0.20.1-0.10.2
Novelty place preference0.00.00.1-0.2-0.1-0.00.3-0.20.10.10.20.2-0.0
Time in novel zone, NPP test0.10.10.2-0.00.10.10.3-0.40.30.30.30.3-0.2
Total zone transitions, NPP test1.11.63.9-1.0-1.3-0.9-0.81.4-1.4-1.3-1.1-2.01.0
Total locomotion distance, NPP test1.41.93.4-1.3-1.6-1.3-0.41.4-1.6-1.4-1.0-1.81.3
Locomotion velocity, NPP test2.13.04.5-1.7-2.0-1.5-0.61.9-2.1-1.8-1.3-2.11.7
Intraocular pressure1.21.73.9-1.1-1.3-1.6-0.21.1-1.4-1.6-0.7-2.01.1
Delta distance traveled before/after self-admin1.01.12.20.60.90.40.9-1.40.60.91.51.0-1.5
Delta ambulatory time before/after self-admin0.60.71.40.80.90.60.2-0.90.60.81.01.0-1.2
Parametrial fat weight1.12.25.40.41.10.12.1-2.11.81.12.30.7-1.3
Pavlov. Cond. lever latency1.62.06.7-1.0-0.3-1.22.6-0.70.2-0.12.4-0.2-2.0
Pavlov. Cond. magazine entry latency1.11.55.50.90.21.0-2.40.9-0.4-0.2-2.0-0.51.4
Pavlov. Cond. change in total contacts1.01.02.61.31.21.6-1.0-0.81.11.0-0.40.80.4
Pavlov. Cond. index score1.82.28.01.10.31.4-2.80.8-0.30.0-2.6-0.12.0
Pavlov. Cond. latency score1.62.17.11.20.51.5-2.70.50.00.3-2.30.21.9
Pavlov. Cond. lever contacts1.51.75.21.30.71.6-2.30.10.30.6-1.90.51.7
Pavlov. Cond. magazine entry number1.21.55.1-0.50.2-0.62.2-1.30.90.62.30.9-1.1
Pavlov. Cond. intertrial magazine entries1.31.63.4-1.7-1.5-1.81.20.8-1.3-1.40.0-1.5-0.0
Pavlov. Cond. lever-magazine prob. diff.1.82.27.81.00.21.3-2.80.9-0.4-0.1-2.6-0.22.0
Pavlov. Cond. response bias1.72.06.80.90.11.1-2.61.0-0.6-0.2-2.6-0.71.6
Pavlov. Cond. lever latency0.30.40.80.70.70.9-0.0-0.60.70.80.40.7-0.4
Pavlov. Cond. magazine entry latency0.50.61.80.60.80.50.1-0.91.10.80.61.40.0
Pavlov. Cond. change in total contacts0.10.20.7-0.4-0.1-0.50.8-0.50.3-0.00.70.2-0.0
Pavlov. Cond. index score0.00.00.1-0.2-0.1-0.30.2-0.10.1-0.10.10.20.2
Pavlov. Cond. latency score0.00.10.2-0.10.1-0.30.3-0.30.30.00.30.4-0.0
Pavlov. Cond. lever contacts0.50.71.9-1.1-0.9-1.40.80.4-0.6-1.00.2-0.80.4
Pavlov. Cond. magazine entry number0.20.20.6-0.1-0.30.1-0.40.7-0.7-0.3-0.8-0.5-0.3
Pavlov. Cond. intertrial magazine entries0.91.24.20.6-0.10.6-2.01.2-0.8-0.4-1.9-0.80.5
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.1-0.1-0.30.2-0.10.1-0.10.10.20.2
Pavlov. Cond. response bias0.30.40.9-0.8-0.7-1.00.30.3-0.3-0.80.0-0.60.8
Time in closed arm before self-admin0.00.00.10.0-0.00.0-0.00.1-0.10.00.10.2-0.2
Time in closed arm after self-admin0.40.41.0-0.00.30.11.0-0.90.60.60.80.7-0.7
Time in open arm before self-admin0.30.30.80.2-0.00.1-0.90.6-0.2-0.3-0.9-0.50.7
Time in open arm after self-admin0.50.50.9-0.1-0.4-0.3-0.90.9-0.9-0.8-1.0-0.80.5
Bone: periosteal estimation3.67.411.63.33.43.2-0.0-2.73.03.21.02.9-2.2
Bone: periosteal perimeter1.93.25.72.42.22.4-0.7-1.61.92.10.11.9-0.9
Bone: post-yield work0.70.92.41.61.11.4-1.3-0.10.30.8-1.1-0.3-0.2
Progressive ratio test 1 active lever presses0.10.10.6-0.2-0.3-0.2-0.30.8-0.5-0.2-0.4-0.00.2
Progressive ratio test 1 breakpoint0.10.10.6-0.1-0.3-0.1-0.30.7-0.5-0.1-0.30.10.1
Progressive ratio test 1 inactive lever presses0.20.30.5-0.7-0.6-0.70.60.1-0.5-0.4-0.3-0.40.3
Progressive ratio test 2 active lever presses1.01.11.6-1.0-1.1-1.0-0.11.2-1.0-1.1-0.8-1.21.1
Progressive ratio test 2 breakpoint1.71.93.2-1.4-1.5-1.3-0.21.5-1.4-1.6-1.0-1.81.5
Progressive ratio test 2 inactive lever presses0.10.20.50.40.50.40.2-0.40.70.5-0.10.30.0
Incentive Sensitization - Responses1.21.22.5-1.1-1.2-1.1-0.20.9-0.9-1.3-0.8-1.61.4
Incentive Sensitization - Breakpoint1.41.53.1-1.2-1.3-1.1-0.31.0-1.0-1.4-0.9-1.81.6
Sum of active levers in priming session hrs 5-60.20.20.7-0.2-0.4-0.3-0.50.8-0.5-0.2-0.50.10.1
Progressive ratio3.23.76.30.91.70.62.2-2.42.31.72.51.7-2.3
Food seeking constrained by brief footshock0.00.00.1-0.1-0.1-0.20.10.2-0.1-0.30.1-0.4-0.1
Seeking ratio, punishment vs. effort2.53.15.6-0.8-1.6-0.6-2.12.4-2.2-1.6-2.3-1.41.9
Retroperitoneal fat weight0.31.02.80.50.90.31.1-1.10.90.91.70.5-1.5
Reaction time number correct0.50.72.1-0.8-0.4-1.01.4-0.1-0.2-0.31.1-0.5-1.1
Reaction time mean minus median1.01.34.71.50.91.5-2.20.00.60.2-1.3-0.21.2
Reaction time mean minus median AUC0.70.93.81.10.51.0-1.90.30.1-0.1-1.1-0.51.3
Reaction time num false alarms0.30.50.90.60.70.9-0.0-0.90.70.90.10.8-0.1
Reaction time num false alarms AUC0.60.91.60.81.01.10.0-1.21.01.20.41.3-0.4
Reaction time trials correct on left0.50.72.1-0.8-0.4-1.01.4-0.1-0.2-0.31.1-0.5-1.1
Reaction time trials on left0.40.61.9-0.7-0.3-0.91.4-0.2-0.1-0.21.1-0.5-1.1
Reaction time mean1.21.66.31.60.71.5-2.50.5-0.00.3-1.80.01.2
Reaction time mean AUC1.11.56.01.50.71.5-2.40.5-0.10.2-1.6-0.11.2
Median of all reaction times0.91.24.31.30.61.3-2.10.5-0.20.3-1.60.20.9
Reaction time omissions0.81.13.81.30.61.0-2.00.30.20.2-1.7-0.51.1
Reaction time false alarm rate0.81.22.51.21.11.6-0.9-0.90.91.2-0.41.50.2
Reaction time premature initiation rate1.01.42.20.81.10.91.0-1.31.11.41.51.1-1.3
Reaction time premature initiations1.31.84.20.41.00.41.8-1.41.11.32.00.9-1.9
Std. dev. reaction times1.21.75.61.91.21.8-2.4-0.10.70.7-1.30.40.8
Reaction time trials completed0.40.61.9-0.7-0.3-0.91.4-0.2-0.1-0.21.1-0.5-1.1
Reaction time trials AUC0.40.61.8-0.7-0.4-1.01.4-0.1-0.1-0.21.0-0.6-1.0
Run reversals in cocaine runway, females0.50.51.4-1.0-0.6-1.01.2-0.1-0.3-0.50.6-0.60.1
Run reversals in cocaine runway, males1.21.12.21.51.31.4-0.9-0.61.40.9-0.21.20.0
Latency to leave start box in cocaine runway0.20.20.70.30.20.6-0.3-0.10.50.60.20.9-0.1
Latency to leave start box in cocaine runway, F0.20.20.7-0.0-0.30.2-0.80.6-0.2-0.1-0.6-0.20.6
Latency to leave start box in cocaine runway, M0.90.81.70.10.50.31.0-1.21.10.91.31.2-0.7
Std. dev. time between licks in bursts2.22.65.52.31.72.3-2.1-0.30.91.6-1.51.5-0.2
Total sessions with >9 infusions0.10.10.20.20.20.20.00.20.10.3-0.40.40.1
Short access day 1 total inactive lever presses1.11.22.71.61.21.7-1.3-0.30.71.2-1.10.90.1
Short access day 10 total inactive lever presses0.20.20.40.60.40.6-0.6-0.30.20.4-0.30.20.2
Short access day 1 total infusions0.30.30.80.1-0.20.2-0.70.9-0.5-0.0-0.90.50.2
Short access day 10 total infusions0.10.10.30.20.20.20.10.10.20.4-0.10.6-0.1
Short access total infusions0.10.20.80.30.30.3-0.00.10.20.5-0.20.9-0.2
Short access day 1 locomotion2.22.45.2-0.7-1.3-0.6-1.62.1-1.9-1.3-2.3-1.01.7
Short access day 10 total locomotion1.41.63.51.91.51.9-1.2-0.20.51.5-0.41.3-1.1
Short access total locomotion0.40.50.80.80.50.8-0.90.6-0.20.5-0.90.8-0.3
One hour access (0.3 mA shock)0.81.02.8-0.8-1.0-0.6-0.81.2-0.9-1.0-0.9-0.51.7
Compulsive drug intake1.71.74.4-0.4-1.1-0.2-1.92.1-1.7-1.0-1.5-0.11.3
One hour access (shock baseline)0.20.20.80.30.50.00.6-0.60.90.20.4-0.3-0.0
Social response proportion1.01.13.11.41.11.3-0.7-0.10.21.10.11.7-1.3
Social responses0.70.92.10.90.91.0-0.1-0.60.31.00.71.5-1.4
Social time1.62.14.91.91.42.2-2.0-0.21.11.1-0.81.60.4
Soleus weight2.36.816.53.83.04.1-2.8-0.91.72.9-1.62.3-0.8
Bone: stiffness0.61.02.70.00.6-0.11.6-1.41.00.71.60.5-0.6
Tibialis anterior weight0.20.61.6-1.2-0.8-1.31.20.0-0.5-0.60.2-0.6-0.0
Time to tail flick, vehicle, before self-admin0.30.31.3-0.2-0.3-0.1-0.60.10.3-0.5-0.5-0.81.1
Time to tail flick, vehicle, after self-admin0.60.72.40.60.00.4-1.50.8-0.3-0.2-1.4-0.30.9
Time to tail flick, test, before self-admin0.20.20.5-0.7-0.4-0.50.5-0.30.3-0.40.6-0.50.4
Time to tail flick, test, after self-admin1.51.63.8-0.5-0.8-0.6-1.00.7-1.0-1.4-1.6-1.91.9
Delta time to tail flick, vehicle, before/after SA0.40.41.0-0.3-0.5-0.4-0.61.0-0.9-0.7-0.7-0.50.6
Delta time to tail flick, test, before/after SA1.31.22.5-0.6-0.9-0.8-0.51.1-1.3-1.2-1.4-1.61.2
Tibia length3.49.715.13.93.93.8-0.1-3.03.43.71.23.3-2.5
Ambulatory time before self-admin0.10.10.20.20.1-0.0-0.1-0.20.30.0-0.4-0.20.4
Ambulatory time after self-admin0.40.40.91.00.90.7-0.2-0.70.50.60.30.6-0.9
Bone: tissue strength2.42.34.80.51.20.51.8-2.22.01.42.11.4-1.0
Total heroin consumption0.10.10.3-0.0-0.1-0.2-0.10.1-0.4-0.1-0.5-0.10.2
Bone: trabecular number2.64.16.8-2.4-2.5-2.60.11.7-2.0-2.5-1.0-1.62.3
Bone: trabecular spacing4.45.78.22.42.82.50.6-2.52.72.92.02.4-2.3
Bone: trabecular thickness1.72.03.3-1.7-1.7-1.80.01.3-1.4-1.8-0.9-0.91.5
Bone: trabecular tissue density1.31.93.40.61.20.91.1-1.81.71.41.81.6-1.0
Water consumed over 24 hours0.10.20.40.50.40.6-0.5-0.10.20.4-0.20.5-0.0
Number of responses in last shaping day1.01.02.41.11.01.4-0.5-0.30.71.3-0.41.6-0.8