Hub : Genes

Mrpl42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr7_32019143_32023936 0.07 0.04 2.9e-03 0.03 0.03 0.02 0.03 2.8e-03 1.2e-03 1.3e-02 1.3e-03
2 PL mRNA stability Mrpl42 0.1 0.05 1.8e-06 0.08 0.04 0.07 0.01 3.0e-09 1.8e-05 9.5e-08 1.0e-02
3 Brain gene expression Mrpl42 0.26 0.08 0.0e+00 0.23 0.21 0.23 0.23 1.4e-21 2.3e-19 4.9e-21 3.8e-21
4 NAcc gene expression Mrpl42 0.1 0.04 3.9e-13 0.1 0.09 0.1 0.1 3.8e-15 2.0e-13 2.2e-15 2.2e-15
5 Adipose gene expression Mrpl42 0.08 0.03 4.1e-08 0.05 0.05 0.04 0.06 3.0e-06 1.1e-06 5.2e-05 8.2e-07
6 BLA gene expression Mrpl42 0.27 0.09 1.6e-07 0.16 0.11 0.1 0.15 1.3e-08 1.7e-06 3.6e-06 2.0e-08
7 OFC gene expression Mrpl42 0.26 0.11 6.3e-04 0.15 0.1 0.09 0.11 2.5e-04 2.1e-03 3.2e-03 1.5e-03
8 PL gene expression Mrpl42 0.12 0.04 5.4e-13 0.15 0.12 0.14 0.14 5.3e-16 1.2e-12 9.1e-15 2.1e-15
9 pVTA gene expression Mrpl42 0.14 0.05 1.0e-11 0.14 0.14 0.12 0.14 2.3e-11 9.8e-12 4.1e-10 1.0e-11
10 Liver gene expression Mrpl42 0.19 0.08 2.2e-07 0.04 0.06 0.07 0.07 2.4e-05 1.0e-07 3.0e-08 3.3e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.91.52.71.00.6-0.6-1.3-1.2-1.7-1.5-1.5-0.3-1.5
Area under the delay curve1.11.32.80.60.4-0.8-1.0-1.1-1.2-1.3-1.3-1.3-1.7
BMI with tail0.41.34.2-0.11.4-1.2-1.1-1.0-0.7-0.7-0.7-1.5-2.0
BMI without tail0.41.15.32.3-2.0-0.4-0.6-0.4-0.2-0.2-0.2-0.6-0.6
Body weight1.14.930.05.5-3.4-0.7-1.0-0.9-0.6-0.6-0.6-1.8-0.7
Weight adjusted by age1.21.92.71.3-0.81.41.61.51.41.51.51.60.6
Bone surface0.10.10.80.90.20.10.10.0-0.1-0.0-0.0-0.0-0.4
Bone volume0.20.40.91.00.3-0.3-0.6-0.6-0.8-0.7-0.7-0.2-0.8
Breakpoint value in progressive ratio session0.91.13.6-0.20.71.01.11.01.01.01.01.01.9
Number of licking bursts0.20.42.8-0.51.70.00.1-0.0-0.0-0.0-0.0-0.2-0.9
Context. condit. distance diff. score0.91.13.60.5-1.0-1.2-1.0-1.0-0.8-0.8-0.8-0.7-1.9
Locomotion velocity, session 10.80.91.6-0.40.81.31.11.10.90.90.91.00.9
Locomotion distance, session 10.81.01.7-0.20.41.11.31.21.21.21.20.21.1
Locomotion velocity, session 20.50.62.60.8-1.60.2-0.0-0.0-0.1-0.1-0.10.01.6
Locomotion distance, session 21.01.42.81.00.11.51.41.31.21.21.20.31.7
Locomotion velocity, session 30.60.72.41.6-1.5-0.1-0.3-0.4-0.5-0.5-0.50.40.9
Locomotion distance, session 30.20.20.50.40.2-0.7-0.4-0.5-0.4-0.4-0.4-0.6-0.7
Stereotopy head waving bouts, day 32.12.54.01.8-1.81.91.51.51.21.21.22.01.4
Stereotopy head waving duration, day 31.21.43.61.4-1.91.20.80.90.70.70.71.61.2
Locomotion velocity, session 70.40.41.61.3-0.30.70.60.40.30.30.30.50.8
Locomotion distance, session 70.20.20.80.00.7-0.3-0.1-0.3-0.4-0.4-0.4-0.90.4
Stereotopy head waving bouts, day 70.40.50.90.9-0.9-0.5-0.6-0.6-0.7-0.7-0.70.2-0.9
Stereotopy head waving duration, day 70.20.20.50.3-0.6-0.5-0.4-0.4-0.4-0.4-0.40.2-0.7
Locomotion velocity, session 80.50.64.70.6-2.20.20.10.30.40.40.40.40.3
Locomotion distance, session 80.71.05.22.3-1.40.60.70.60.60.60.60.10.0
Degree of sensitization distance0.30.31.2-0.40.20.60.60.50.40.40.4-0.11.1
Degree of sensitization stereotypy0.90.91.9-0.2-0.3-1.4-1.1-1.1-1.0-1.0-1.0-0.6-1.3
Conditioned locomotion0.70.82.00.4-0.1-0.3-0.9-1.0-1.1-1.4-1.4-1.0-0.1
Cocaine response after cond. corrected0.40.41.9-0.30.3-0.4-0.6-0.6-0.4-0.6-0.6-0.6-1.4
Cocaine response after cond. not corrected0.20.20.9-0.20.6-0.3-0.4-0.4-0.4-0.4-0.4-0.5-1.0
Cocaine response before conditioning0.50.61.0-0.20.60.70.70.90.71.01.00.51.0
Saline control response0.10.21.01.0-0.8-0.20.2-0.10.20.00.00.2-0.4
Bone: connectivity density0.30.41.10.9-0.41.00.50.60.20.30.30.9-0.4
Bone: cortical apparent density0.10.10.40.4-0.3-0.0-0.3-0.3-0.4-0.4-0.4-0.7-0.2
Bone: cortical area1.11.62.30.51.3-1.1-1.4-1.3-1.5-1.4-1.4-1.3-1.4
Bone: cortical porosity0.60.63.51.3-1.9-0.1-0.2-0.2-0.2-0.2-0.20.10.7
Bone: cortical porosity0.40.52.21.2-1.50.1-0.1-0.0-0.1-0.1-0.10.20.9
Bone: cortical thickness1.01.62.70.60.8-1.0-1.5-1.3-1.6-1.5-1.5-1.3-1.0
Bone: cortical thickness0.60.81.2-0.80.9-0.8-1.1-0.9-1.1-1.0-1.0-0.70.0
Bone: cortical tissue density0.10.20.40.6-0.4-0.0-0.3-0.3-0.4-0.4-0.4-0.6-0.2
Condit. Reinf. active minus inactive responses0.80.93.2-0.71.80.90.90.80.60.60.61.10.7
Condit. Reinf. active-inactive response ratio0.60.64.5-0.82.10.30.20.20.00.00.00.7-0.1
Condit. Reinf. active responses0.91.14.3-1.12.10.90.90.80.60.60.61.30.8
Condit. Reinf. inactive responses0.40.41.5-1.20.60.20.50.50.50.50.50.50.9
Incentive salience index mean1.41.73.80.21.91.61.51.41.11.11.11.70.8
Condit. Reinf. lever presses1.11.62.51.11.21.61.51.41.11.11.11.50.8
Condit. Reinf. active minus inactive responses0.60.82.6-0.2-0.70.60.90.90.90.90.90.71.6
Condit. Reinf. active-inactive response ratio0.20.21.4-0.1-1.2-0.6-0.2-0.2-0.00.00.00.10.3
Condit. Reinf. active responses0.81.02.6-0.8-0.20.61.21.01.21.21.20.41.6
Condit. Reinf. inactive responses0.91.22.3-1.51.00.71.11.01.01.21.2-0.01.4
Condit. Reinf. lever presses2.23.04.90.1-1.71.41.81.82.02.02.01.52.2
Condit. Reinf. lever reinforcers received0.50.82.6-1.0-0.00.30.90.80.90.90.90.01.6
Conditioned reinforcement - actives1.42.45.72.4-2.01.51.41.41.31.31.31.40.9
Conditioned reinforcement - inactives1.31.96.52.6-1.31.61.11.00.80.70.71.31.5
Conditioned locomotion0.20.31.51.2-0.90.20.10.00.0-0.0-0.0-0.10.5
Patch foraging indifference point 0 sec0.91.62.60.9-0.5-1.2-1.4-1.4-1.6-1.5-1.5-1.0-1.2
Patch foraging indifference point AUC0.20.31.41.2-0.80.40.20.20.10.10.10.30.4
Delay disc. indifference point, 0s delay0.50.62.41.6-0.70.80.70.60.50.40.40.60.7
Delay disc. indifference point, 16s delay2.52.74.00.21.1-1.4-1.6-1.7-1.9-1.9-1.9-2.0-1.8
Delay disc. indifference point, 2s delay0.50.51.51.2-0.80.60.60.60.60.60.60.3-0.9
Delay disc. indifference point, 24s delay1.51.72.70.30.3-1.2-1.5-1.5-1.6-1.6-1.6-1.5-0.9
Delay disc. indifference point, 4s delay0.40.40.8-0.4-0.0-0.7-0.6-0.6-0.5-0.6-0.6-0.8-0.9
Delay disc. indifference point, 8s delay2.12.55.5-0.10.6-1.6-1.6-1.6-1.6-1.7-1.7-1.7-2.4
Indifference point function ln k0.61.01.9-1.41.2-1.1-0.8-1.0-0.8-0.9-0.9-1.0-0.4
Indifference point function log k0.61.01.9-1.41.2-1.1-0.8-1.0-0.8-0.9-0.9-1.0-0.4
Patch foraging total patch changes 0 sec0.71.42.21.0-0.6-1.0-1.3-1.3-1.5-1.4-1.4-1.0-0.9
Patch foraging total patch changes 12 sec0.50.63.01.7-0.90.50.30.30.10.10.10.5-1.3
Patch foraging total patch changes 18 sec0.71.12.41.5-0.8-0.6-1.1-0.9-1.1-1.0-1.0-0.4-1.6
Patch foraging total patch changes 24 sec0.61.12.11.4-1.5-1.0-1.1-0.9-1.1-0.9-0.9-0.5-0.9
Patch foraging total patch changes 6 sec0.50.81.6-0.40.1-1.1-1.0-1.0-1.0-0.9-0.9-0.8-1.3
Patch foraging time to switch 0 sec0.20.50.90.2-0.41.00.70.80.70.80.80.4-0.9
Patch foraging water rate 0 sec0.10.32.01.40.3-0.2-0.1-0.2-0.2-0.2-0.20.0-0.3
Patch foraging water rate 12 sec0.20.41.21.1-0.2-0.4-0.3-0.5-0.4-0.5-0.5-0.0-1.1
Patch foraging water rate 18 sec0.20.30.90.20.30.50.60.50.50.40.41.00.9
Patch foraging water rate 24 sec0.30.43.21.8-0.2-0.4-0.0-0.3-0.1-0.1-0.10.2-0.1
Patch foraging water rate 6 sec1.42.06.32.5-1.01.21.41.21.41.41.41.4-0.3
Seeking ratio, delayed vs. immediate footshock0.20.30.70.80.80.60.20.1-0.2-0.2-0.20.60.7
Distance traveled before self-admin1.31.72.31.0-0.81.51.51.51.51.51.51.30.8
Distance traveled after self-admin0.30.41.91.4-0.5-0.1-0.2-0.3-0.4-0.4-0.4-0.40.9
Extensor digitorum longus weight0.00.10.10.3-0.40.20.20.30.40.30.3-0.10.3
Bone: elastic displacement0.60.75.0-2.20.4-0.10.20.40.50.70.70.60.4
Bone: elastic work1.31.72.9-1.70.6-1.7-1.5-1.4-1.4-1.3-1.3-1.0-0.6
Bone: endosteal estimation0.20.51.0-0.31.0-1.0-0.6-0.8-0.5-0.5-0.5-0.7-0.8
Bone: endosteal perimeter0.40.82.00.11.4-1.0-0.6-0.8-0.5-0.5-0.5-0.8-1.4
Epididymis fat weight0.72.34.01.4-0.71.51.61.72.01.91.91.2-0.4
Delta time in closed arm before/after self-admin0.30.31.1-1.00.10.20.40.40.60.50.50.10.5
Delta time in open arm before/after self-admin0.40.40.8-0.40.5-0.7-0.7-0.7-0.9-0.8-0.8-0.20.0
Diff in mean of infusions in LGA sessions0.40.41.6-1.10.90.20.40.40.40.30.30.41.2
Delay discount exponential model param1.21.32.8-0.5-0.30.91.11.21.21.31.31.31.7
Extinction: sum of active levers before priming0.40.50.8-0.40.4-0.8-0.9-0.8-0.9-0.8-0.8-0.70.1
Active lever presses in extinction session 61.31.31.90.70.31.31.41.31.31.31.31.01.1
Bone: final force4.67.310.5-0.12.3-2.7-3.0-3.0-3.2-3.2-3.2-2.7-2.2
Bone: final moment4.16.59.5-0.02.3-2.5-2.8-2.8-3.1-3.0-3.0-2.5-2.1
Food consumed during 24 hour testing period0.81.01.9-0.80.1-1.4-1.3-1.3-1.0-1.1-1.1-0.9-0.3
Glucose0.10.20.6-0.80.7-0.3-0.4-0.3-0.2-0.3-0.3-0.20.3
Heart weight0.81.33.92.00.31.61.31.11.00.90.90.60.7
Delay discount hyperbolic model param0.80.92.4-0.6-0.20.70.80.91.01.01.01.11.5
Intermittent access intake day 1-15 change1.02.13.90.3-0.01.51.81.82.01.91.91.10.4
Intermittent access intake escalation1.02.13.90.3-0.11.51.81.82.01.91.91.10.4
Intermittent access intake escalation 21.41.63.00.5-0.31.31.51.51.71.61.60.90.2
Intermitt. access day 1 inactive lever presses0.41.52.8-0.40.2-1.1-1.3-1.3-1.5-1.6-1.6-0.71.7
Intermitt. access day 15 inactive lever presses0.20.41.70.2-0.4-0.4-0.6-0.5-0.6-0.6-0.6-0.31.3
Intermitt. access escalation Index0.70.91.4-1.20.20.71.01.01.11.21.21.20.2
Intermittent access day 1 total infusions0.81.32.2-0.0-1.2-1.5-1.3-1.2-0.9-0.9-0.9-1.5-1.2
Intermittent access day 15 total infusions0.30.52.70.7-1.7-0.00.30.40.80.70.7-0.2-0.2
Intermittent access terminal intake (last 3 days)0.30.52.50.7-1.6-0.10.20.30.70.60.6-0.4-0.1
Intermittent access total infusions0.70.82.00.5-1.4-1.2-0.9-0.8-0.5-0.5-0.5-1.3-0.5
Intermittent access day 1 locomotion2.73.45.2-0.2-0.8-2.3-2.3-2.2-2.0-2.0-2.0-2.3-0.8
Intermittent access day 15 total locomotion1.42.63.80.6-0.9-1.8-2.0-1.9-1.8-1.9-1.9-1.7-0.5
Intermittent access total locomotion2.02.43.40.7-1.7-1.8-1.8-1.8-1.6-1.6-1.6-1.7-0.4
Intermittent access standard deviation0.20.51.30.6-0.20.60.70.70.80.80.8-0.0-1.1
Left kidney weight0.31.47.12.7-2.6-0.3-0.1-0.10.30.30.3-0.5-0.0
Right kidney weight0.21.16.12.5-1.60.20.40.30.70.60.6-0.1-0.7
Cocaine induced anxiety0.20.31.5-0.81.2-0.3-0.2-0.2-0.3-0.2-0.2-0.30.5
Post-drug Anxiety0.30.30.5-0.70.40.30.40.60.60.70.70.6-0.2
Baseline Anxiety0.40.52.60.7-1.60.30.30.40.50.40.40.6-0.5
Tail length1.97.535.66.0-5.9-0.4-0.9-0.7-0.5-0.6-0.6-0.71.2
Length with tail2.310.055.37.4-6.50.1-0.4-0.4-0.1-0.2-0.2-0.91.1
Length without tail0.93.017.84.2-2.9-0.3-0.6-0.7-0.6-0.6-0.6-1.40.5
Times rat made contact with spout1.01.13.8-0.01.9-0.5-0.8-0.8-1.0-1.1-1.1-0.8-1.4
Lifetime Intake0.70.81.90.5-1.1-1.1-0.9-0.8-0.5-0.5-0.5-1.3-1.4
Liver weight, left1.22.010.03.2-1.71.30.60.70.70.50.51.4-1.3
Liver weight, right1.22.17.42.7-2.71.10.70.90.70.80.81.01.1
Locomotor activity0.81.25.62.4-0.01.31.20.81.00.70.70.31.1
Locomotor testing distance0.40.71.61.30.91.01.10.80.90.70.70.3-0.0
Locomotor testing rearing0.51.01.71.30.41.21.21.11.01.01.00.9-0.2
Locomotion in novel chamber0.20.21.00.61.00.60.20.2-0.1-0.1-0.10.40.6
Locomotion in novel chamber post-restriction0.30.41.00.1-0.90.40.60.50.80.70.70.4-1.0
Fecal boli incidents, locomotor time 10.00.10.20.5-0.40.00.0-0.1-0.0-0.1-0.1-0.0-0.5
Change in fecal boli incidents, locomotor task2.12.13.7-1.41.9-1.4-1.4-1.4-1.6-1.5-1.5-1.5-1.0
Time >=10cm from walls, locomotor time 10.10.11.1-1.0-0.0-0.4-0.1-0.00.10.10.1-0.10.3
Bouts of movement, locomotor time 10.30.31.00.4-0.00.70.70.50.50.40.40.31.0
Total resting periods, locomotor time 10.30.42.00.2-0.10.70.60.50.40.30.30.21.4
Rest time, locomotor task time 10.20.20.7-0.3-0.50.40.40.40.20.30.30.60.9
Distance moved, locomotor task time 10.50.72.61.6-0.10.90.80.80.70.70.70.9-0.5
Vertical activity count, locomotor time 10.20.50.80.80.40.80.90.80.80.80.80.30.3
Time >=10cm from walls, locomotor time 20.40.61.4-1.21.0-0.7-0.6-0.6-0.7-0.6-0.6-0.1-0.9
Bouts of movement, locomotor time 20.40.60.90.5-1.00.80.80.80.80.80.80.40.7
Total resting periods, locomotor time 20.20.30.40.2-0.60.60.60.60.60.60.60.30.3
Rest time, locomotor task time 20.40.52.0-1.40.60.30.50.50.60.60.60.11.1
Distance moved, locomotor task time 21.01.22.21.5-1.10.91.01.11.11.11.11.30.2
Vertical activity count, locomotor time 20.91.34.22.0-1.11.01.11.01.01.01.01.00.3
Light reinforcement 10.30.71.4-0.00.10.51.00.91.01.21.20.60.7
Light reinforcement 20.20.41.1-0.6-0.0-1.0-0.5-0.6-0.4-0.2-0.2-0.5-1.0
Bone: marrow area0.20.51.1-0.41.0-1.0-0.6-0.8-0.5-0.6-0.6-0.7-0.8
Bone: maximum diameter0.61.02.40.21.5-1.0-0.9-1.0-1.0-0.9-0.9-1.1-1.1
Bone: maximum force1.83.24.4-0.51.4-2.1-2.0-2.0-2.1-2.0-2.0-2.1-0.8
Bone: maximum moment1.72.94.0-0.41.6-1.9-1.9-1.9-2.0-1.9-1.9-2.0-0.8
Mean time between licks in bursts0.30.71.8-0.60.40.61.20.91.41.01.00.5-0.1
Mean num. licks in bursts0.10.20.30.10.1-0.3-0.5-0.4-0.5-0.6-0.6-0.30.2
Cd content in liver0.30.30.8-0.40.7-0.7-0.2-0.4-0.3-0.3-0.3-0.90.8
Co content in liver0.30.31.30.9-0.50.10.50.30.40.40.41.10.1
Cu content in liver0.80.94.81.3-2.20.20.30.30.40.40.40.71.2
Fe content in liver1.31.52.30.8-0.3-1.2-1.3-1.5-1.5-1.5-1.5-1.5-0.5
K content in liver3.23.013.32.7-3.71.31.01.00.90.90.91.60.9
Mg content in liver2.32.44.71.9-2.21.61.41.41.31.21.21.71.2
Mn content in liver0.70.81.30.6-1.01.10.91.00.90.90.90.51.0
Na content in liver0.50.60.9-0.2-1.0-0.9-0.8-0.8-0.8-0.8-0.8-0.9-0.4
Rb content in liver0.60.62.80.7-1.7-0.7-0.7-0.8-0.7-0.7-0.7-0.2-0.2
Se content in liver0.20.21.40.3-0.8-0.1-0.0-0.00.00.00.0-0.31.2
Sr content in liver0.50.41.61.30.80.4-0.2-0.1-0.6-0.6-0.60.8-0.4
Zn content in liver1.41.57.11.7-2.70.10.70.50.80.80.80.41.6
Bone: minimum diameter1.42.64.10.61.7-1.5-1.5-1.6-1.6-1.5-1.5-2.0-1.9
Time in familiar zone, hab. session 10.10.10.4-0.60.1-0.2-0.0-0.00.00.00.0-0.10.3
Time in novel zone, hab. session 12.42.44.4-1.61.6-1.7-1.5-1.6-1.5-1.5-1.5-2.1-1.1
Total zone transitions, hab. session 13.95.410.72.5-0.13.32.82.72.32.32.31.91.5
Total locomotion distance, hab. session 17.510.617.52.7-0.84.24.03.83.53.53.52.92.3
Locomotion velocity, hab. session 111.516.327.23.6-1.25.24.84.74.24.24.24.02.6
Time in familiar zone, hab. session 20.40.41.1-0.6-0.10.30.70.60.80.80.80.11.0
Time in novel zone, hab. session 20.40.40.7-0.30.8-0.5-0.8-0.7-0.8-0.8-0.8-0.4-0.2
Total zone transitions, hab. session 20.91.12.10.51.31.31.51.21.01.01.00.21.1
Total locomotion distance, hab. session 25.67.312.01.20.73.43.53.23.03.03.02.41.9
Locomotion velocity, hab. session 26.18.213.31.50.53.63.63.43.23.23.22.72.0
Novel to familiar place preference ratio0.30.31.6-0.2-1.3-0.10.00.10.20.20.20.11.0
Novelty place preference0.20.21.1-0.4-1.0-0.2-0.10.00.10.10.10.21.0
Time in novel zone, NPP test0.20.20.7-0.7-0.7-0.5-0.4-0.3-0.2-0.2-0.2-0.30.8
Total zone transitions, NPP test1.11.53.21.70.31.61.41.21.01.01.00.41.8
Total locomotion distance, NPP test7.910.716.52.5-1.04.14.03.83.63.63.62.82.7
Locomotion velocity, NPP test7.810.916.72.7-1.24.14.03.83.53.53.53.02.8
Intraocular pressure0.30.43.0-0.60.6-0.10.10.10.30.20.20.7-1.7
Delta distance traveled before/after self-admin0.40.52.01.4-0.8-0.3-0.2-0.4-0.5-0.5-0.5-0.30.9
Delta ambulatory time before/after self-admin1.11.42.20.5-0.1-1.3-1.2-1.4-1.5-1.5-1.5-1.20.3
Parametrial fat weight0.10.31.8-0.91.3-0.0-0.1-0.1-0.2-0.2-0.2-0.70.5
Pavlov. Cond. lever latency0.20.31.1-0.7-0.6-0.6-0.5-0.4-0.2-0.2-0.2-1.10.0
Pavlov. Cond. magazine entry latency0.50.74.0-1.52.0-0.30.1-0.0-0.0-0.0-0.0-0.6-0.1
Pavlov. Cond. change in total contacts0.60.63.1-1.11.8-0.10.10.00.10.10.1-0.2-1.3
Pavlov. Cond. index score0.40.52.8-0.51.70.60.70.60.50.50.50.50.0
Pavlov. Cond. latency score0.40.51.8-0.21.30.70.70.70.50.50.50.7-0.0
Pavlov. Cond. lever contacts0.30.41.00.50.70.80.80.70.50.50.51.0-0.0
Pavlov. Cond. magazine entry number0.50.64.31.2-2.10.1-0.00.00.10.10.10.60.4
Pavlov. Cond. intertrial magazine entries2.12.53.3-0.91.7-1.6-1.7-1.7-1.7-1.7-1.7-1.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.40.52.6-0.51.60.60.70.60.40.40.40.30.1
Pavlov. Cond. response bias0.40.54.3-0.92.10.20.30.20.00.00.0-0.0-0.2
Pavlov. Cond. lever latency0.10.20.80.9-0.30.1-0.2-0.2-0.4-0.4-0.40.3-0.1
Pavlov. Cond. magazine entry latency0.10.20.9-0.90.6-0.4-0.1-0.00.20.10.1-0.2-0.5
Pavlov. Cond. change in total contacts0.10.10.30.5-0.4-0.2-0.00.00.20.10.1-0.5-0.4
Pavlov. Cond. index score0.10.10.3-0.60.2-0.3-0.00.00.30.20.2-0.5-0.4
Pavlov. Cond. latency score0.10.10.2-0.4-0.0-0.10.20.20.40.40.4-0.1-0.2
Pavlov. Cond. lever contacts0.20.21.0-1.00.6-0.20.20.20.40.40.4-0.5-0.2
Pavlov. Cond. magazine entry number0.20.20.80.7-0.9-0.1-0.2-0.4-0.5-0.5-0.50.10.4
Pavlov. Cond. intertrial magazine entries0.71.14.30.1-1.00.70.80.90.71.01.00.62.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.40.1-0.2-0.00.00.20.20.2-0.4-0.5
Pavlov. Cond. response bias0.20.31.1-1.00.8-0.30.10.10.40.30.3-0.6-0.5
Time in closed arm before self-admin0.00.00.10.20.3-0.1-0.1-0.1-0.2-0.1-0.1-0.20.3
Time in closed arm after self-admin0.50.52.0-1.41.00.20.40.40.50.50.50.0-1.0
Time in open arm before self-admin0.40.51.3-0.00.10.80.70.70.70.70.70.71.2
Time in open arm after self-admin0.40.41.7-0.00.2-0.4-0.5-0.6-0.7-0.7-0.7-0.01.3
Bone: periosteal estimation0.71.51.90.11.3-1.4-1.2-1.3-1.3-1.2-1.2-1.4-1.1
Bone: periosteal perimeter0.30.61.50.41.2-0.7-0.7-0.8-0.8-0.7-0.7-0.8-0.6
Bone: post-yield work1.31.93.7-1.31.2-1.5-1.4-1.4-1.3-1.3-1.3-1.9-0.2
Progressive ratio test 1 active lever presses1.01.25.02.2-2.2-0.4-0.4-0.4-0.2-0.2-0.2-0.7-1.0
Progressive ratio test 1 breakpoint0.91.14.92.2-2.2-0.4-0.3-0.3-0.2-0.1-0.1-0.7-1.0
Progressive ratio test 1 inactive lever presses0.30.52.01.4-1.40.30.10.20.20.10.10.30.8
Progressive ratio test 2 active lever presses2.83.26.52.2-2.61.51.71.71.91.81.81.50.4
Progressive ratio test 2 breakpoint2.83.26.22.1-2.51.51.71.81.91.91.91.50.3
Progressive ratio test 2 inactive lever presses0.40.72.61.4-1.60.50.50.50.60.50.50.70.5
Incentive Sensitization - Responses2.83.95.21.7-1.52.22.12.22.32.22.22.10.6
Incentive Sensitization - Breakpoint2.93.85.21.6-1.42.12.12.22.32.22.22.10.7
Sum of active levers in priming session hrs 5-61.00.91.40.80.11.11.21.21.21.21.20.8-0.2
Progressive ratio0.20.20.80.4-0.90.10.40.40.50.50.50.7-0.0
Food seeking constrained by brief footshock0.81.03.61.4-1.9-0.8-0.6-0.6-0.5-0.5-0.5-0.5-1.4
Seeking ratio, punishment vs. effort0.10.20.50.2-0.2-0.4-0.5-0.5-0.5-0.5-0.5-0.7-0.2
Retroperitoneal fat weight0.62.47.72.8-1.01.81.41.51.51.41.41.4-0.0
Reaction time number correct0.30.54.2-0.12.1-0.1-0.2-0.3-0.4-0.4-0.40.0-0.8
Reaction time mean minus median0.30.86.9-0.6-0.7-0.1-0.0-0.2-0.1-0.2-0.2-0.12.6
Reaction time mean minus median AUC0.30.86.2-0.9-0.7-0.00.20.10.10.00.00.02.5
Reaction time num false alarms0.60.81.9-1.10.4-1.0-0.7-0.8-0.9-0.8-0.8-0.71.4
Reaction time num false alarms AUC0.40.73.0-1.20.6-0.6-0.4-0.5-0.6-0.5-0.5-0.31.7
Reaction time trials correct on left0.30.54.2-0.12.1-0.1-0.2-0.3-0.4-0.4-0.40.0-0.8
Reaction time trials on left0.30.64.8-0.32.2-0.2-0.2-0.3-0.4-0.4-0.4-0.0-0.8
Reaction time mean0.10.21.0-0.10.40.10.40.30.40.40.40.21.0
Reaction time mean AUC0.20.21.30.1-0.20.20.40.40.40.50.50.21.2
Median of all reaction times0.10.20.30.20.50.10.50.40.50.60.60.20.1
Reaction time omissions1.82.713.7-3.72.5-1.3-0.8-1.0-0.7-0.9-0.9-1.10.5
Reaction time false alarm rate0.40.53.5-0.9-0.6-0.4-0.2-0.3-0.2-0.2-0.2-0.21.9
Reaction time premature initiation rate1.82.53.90.4-0.11.82.01.91.91.81.81.70.6
Reaction time premature initiations1.12.03.20.50.61.71.81.71.71.61.61.70.3
Std. dev. reaction times0.40.76.3-1.0-0.1-0.10.2-0.00.1-0.0-0.0-0.22.5
Reaction time trials completed0.30.64.8-0.32.2-0.2-0.2-0.3-0.4-0.4-0.4-0.0-0.8
Reaction time trials AUC0.30.54.1-0.02.00.10.0-0.1-0.2-0.2-0.20.2-0.8
Run reversals in cocaine runway, females4.14.15.12.0-1.82.22.22.22.22.22.22.10.6
Run reversals in cocaine runway, males1.71.72.3-1.51.1-1.4-1.3-1.4-1.4-1.4-1.4-1.4-0.9
Latency to leave start box in cocaine runway0.20.21.1-0.81.00.30.30.30.30.30.3-0.00.1
Latency to leave start box in cocaine runway, F0.20.31.3-1.01.2-0.10.10.10.10.20.2-0.30.1
Latency to leave start box in cocaine runway, M0.30.30.70.20.00.80.60.70.60.60.60.60.4
Std. dev. time between licks in bursts0.40.61.3-1.00.40.21.10.71.20.80.80.10.8
Total sessions with >9 infusions0.60.72.71.3-1.3-0.3-0.2-0.3-0.1-0.2-0.2-0.6-1.7
Short access day 1 total inactive lever presses0.20.30.8-0.60.8-0.6-0.5-0.5-0.4-0.4-0.4-0.90.1
Short access day 10 total inactive lever presses0.41.13.3-1.80.4-0.7-0.8-0.7-0.9-0.9-0.90.11.7
Short access day 1 total infusions0.20.21.30.0-0.6-0.20.10.10.50.40.4-0.2-1.1
Short access day 10 total infusions2.53.14.80.5-1.1-2.1-2.1-2.0-1.9-1.9-1.9-2.2-1.2
Short access total infusions0.81.14.50.4-0.7-1.1-0.9-0.9-0.7-0.7-0.7-1.2-2.1
Short access day 1 locomotion0.91.11.80.2-1.1-1.3-1.2-1.2-1.1-1.1-1.1-1.1-0.6
Short access day 10 total locomotion1.22.23.80.3-0.5-1.3-1.7-1.8-1.9-1.9-1.9-1.40.6
Short access total locomotion2.12.53.61.0-1.1-1.6-1.8-1.8-1.8-1.9-1.9-1.5-1.0
One hour access (0.3 mA shock)1.92.29.23.0-2.01.41.21.11.11.11.10.7-0.4
Compulsive drug intake0.50.61.40.40.1-0.4-0.7-0.9-1.1-1.2-1.2-0.2-0.9
One hour access (shock baseline)1.42.25.12.3-1.61.41.41.41.61.61.60.80.4
Social response proportion0.40.51.71.3-0.11.00.70.60.40.50.50.20.6
Social responses3.34.27.82.0-0.32.82.32.42.02.02.02.11.6
Social time0.40.51.20.80.41.10.80.80.60.60.60.7-0.9
Soleus weight0.30.93.0-1.21.5-0.7-0.5-0.7-0.5-0.6-0.6-1.7-0.7
Bone: stiffness2.03.26.01.21.0-1.4-1.8-1.9-2.2-2.2-2.2-2.5-0.0
Tibialis anterior weight0.62.02.8-1.41.7-1.3-1.5-1.3-1.4-1.3-1.3-1.5-1.2
Time to tail flick, vehicle, before self-admin0.90.95.4-0.52.30.30.20.20.20.20.2-0.5-1.8
Time to tail flick, vehicle, after self-admin0.10.10.4-0.30.60.20.20.1-0.0-0.0-0.00.40.1
Time to tail flick, test, before self-admin0.10.10.60.30.80.0-0.1-0.3-0.4-0.4-0.4-0.4-0.3
Time to tail flick, test, after self-admin0.90.91.80.60.71.41.21.11.00.90.91.0-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.6-0.7-0.50.00.10.10.10.10.10.60.8
Delta time to tail flick, test, before/after SA0.60.61.30.7-0.90.80.70.80.70.70.71.10.0
Tibia length0.71.914.93.9-1.8-0.1-0.4-0.3-0.3-0.3-0.3-0.50.0
Ambulatory time before self-admin1.01.51.81.1-1.41.21.21.31.31.31.31.20.7
Ambulatory time after self-admin0.30.41.41.2-0.5-0.1-0.2-0.2-0.4-0.3-0.3-0.31.1
Bone: tissue strength0.70.71.10.60.8-0.6-0.6-0.8-1.0-1.0-1.0-1.0-0.5
Total heroin consumption0.70.81.7-0.71.30.71.00.90.90.90.90.60.9
Bone: trabecular number0.30.62.80.70.40.1-0.5-0.4-0.8-0.7-0.70.4-1.7
Bone: trabecular spacing0.60.91.5-1.0-0.90.20.80.81.21.11.10.61.1
Bone: trabecular thickness1.01.32.40.30.5-0.9-1.4-1.2-1.5-1.4-1.4-0.8-1.0
Bone: trabecular tissue density0.20.31.21.1-1.0-0.1-0.2-0.3-0.3-0.4-0.4-0.20.3
Water consumed over 24 hours1.41.93.1-0.10.2-1.6-1.8-1.7-1.6-1.6-1.6-1.5-0.3
Number of responses in last shaping day0.20.31.00.7-1.00.30.40.40.40.40.40.4-0.0