Hub : Genes

Scg3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Scg3 0.34 0.13 4.3e-07 0.3 0.3 0.32 0.3 8.2e-08 7.8e-08 2.9e-08 6.0e-08
2 IL gene expression Scg3 0.23 0.11 1.5e-04 0.1 0.12 0.1 0.08 2.1e-03 1.1e-03 2.8e-03 4.9e-03
3 Brain gene expression Scg3 0.16 0.08 2.1e-07 0.04 0.07 0.07 0.05 1.1e-04 2.9e-07 6.9e-07 1.2e-05
4 BLA mRNA stability Scg3 0.07 0.05 9.5e-04 0.06 0.06 0.05 0.04 3.0e-04 6.1e-04 1.3e-03 3.5e-03
5 NAcc mRNA stability Scg3 0.03 0.02 1.1e-05 0.03 0.03 0.03 0.03 7.0e-06 2.1e-05 1.8e-05 4.0e-05
6 NAcc gene expression Scg3 0.08 0.04 2.5e-09 0.05 0.06 0.05 0.06 2.2e-08 3.6e-09 1.2e-08 3.6e-09
7 IC gene expression Scg3 0.35 0.13 2.9e-08 0.07 0.21 0.17 0.16 4.7e-04 4.3e-09 1.8e-07 4.4e-07
8 Brain mRNA stability Scg3 0.21 0.08 0.0e+00 0.17 0.24 0.24 0.23 4.0e-16 3.9e-22 4.5e-22 1.2e-21
9 PL mRNA stability Scg3 0.07 0.04 1.0e-06 0.02 0.05 0.05 0.04 9.8e-04 4.0e-06 8.5e-06 4.4e-05
10 PL gene expression Scg3 0.12 0.06 4.9e-10 0.07 0.08 0.08 0.07 9.0e-08 3.4e-09 1.2e-08 1.4e-08
11 BLA gene expression Scg3 0.1 0.06 8.4e-03 0 0.01 0.01 0.01 1.9e-01 4.9e-02 1.5e-01 7.0e-02
12 Adipose gene expression Scg3 0.04 0.03 2.0e-03 0.02 0.01 0.01 0.01 1.1e-03 2.6e-02 2.9e-02 9.1e-03
13 Eye gene expression Scg3 0.5 0.17 1.7e-04 0.06 0.12 0.06 0.08 4.1e-02 7.5e-03 5.0e-02 2.2e-02
14 Liver gene expression Scg3 0.02 0.01 5.8e-03 -0 0 -0 -0 5.3e-01 2.2e-01 7.6e-01 9.8e-01
15 IC mRNA stability Scg3 0.09 0.06 2.4e-03 0.04 0.06 0.04 0.02 1.3e-02 1.7e-03 1.4e-02 4.7e-02
16 pVTA gene expression Scg3 0.21 0.1 1.6e-11 0.17 0.12 0.15 0.14 1.9e-13 1.1e-09 3.2e-12 2.4e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.10.20.90.5-0.00.4-0.10.1-0.3-0.1-0.3-0.30.2-0.1-0.90.40.4-0.5-0.9
Area under the delay curve0.81.32.2-1.21.31.21.21.31.31.5-1.0-0.91.51.41.01.00.7-0.0-0.6
BMI with tail2.06.917.2-3.72.81.92.32.74.13.7-1.8-1.62.83.53.41.30.70.80.9
BMI without tail0.63.59.2-1.81.52.51.02.03.02.9-1.0-1.02.43.01.61.10.30.90.4
Body weight1.98.324.7-3.92.42.61.92.45.04.5-1.2-1.22.94.33.90.7-0.21.91.6
Weight adjusted by age0.61.83.2-1.61.61.11.71.31.01.4-1.5-1.81.31.01.11.21.3-1.0-0.9
Bone surface1.52.94.9-1.11.91.31.72.10.71.0-2.2-2.11.70.7-0.72.22.2-1.8-2.1
Bone volume0.71.32.1-0.81.21.11.11.30.70.9-1.4-1.41.30.8-0.41.41.3-1.0-1.5
Breakpoint value in progressive ratio session0.71.42.6-1.21.40.71.31.60.80.8-1.5-1.61.00.5-0.01.31.4-1.3-1.0
Number of licking bursts0.72.34.3-1.41.91.11.91.81.11.4-2.0-2.11.40.90.41.61.8-1.4-1.0
Context. condit. distance diff. score0.40.41.1-0.70.9-0.51.10.60.0-0.1-0.8-0.80.3-0.20.50.60.9-0.9-0.3
Locomotion velocity, session 10.50.61.6-0.40.61.10.40.71.11.1-0.4-0.21.11.30.70.60.10.50.1
Locomotion distance, session 10.40.63.21.2-0.61.5-0.90.3-0.20.20.0-0.20.30.3-1.80.30.1-0.2-0.8
Locomotion velocity, session 20.81.02.1-0.41.01.40.61.31.01.0-0.9-0.91.51.2-0.11.20.8-0.3-1.1
Locomotion distance, session 20.81.16.40.6-0.22.5-0.81.01.11.3-0.1-0.21.41.6-1.30.7-0.20.6-0.4
Locomotion velocity, session 31.92.27.91.20.40.70.11.0-1.1-0.9-1.2-1.10.6-0.8-2.71.81.8-2.0-2.8
Locomotion distance, session 31.61.88.72.3-1.10.2-1.5-0.4-1.8-1.60.40.4-0.5-1.2-2.90.40.3-0.8-1.6
Stereotopy head waving bouts, day 31.01.14.0-0.10.1-2.00.6-0.7-1.6-1.4-0.3-0.5-1.4-1.9-0.2-0.20.7-1.4-0.5
Stereotopy head waving duration, day 30.70.94.8-0.70.5-2.21.0-0.7-1.0-1.0-0.4-0.3-1.1-1.50.7-0.20.6-1.00.1
Locomotion velocity, session 70.10.10.50.4-0.20.0-0.2-0.2-0.7-0.6-0.0-0.1-0.1-0.5-0.60.20.3-0.5-0.3
Locomotion distance, session 70.20.30.8-0.00.30.80.10.70.10.1-0.6-0.60.60.2-0.60.80.7-0.6-0.9
Stereotopy head waving bouts, day 71.11.33.50.60.7-0.40.60.5-1.2-1.1-1.1-0.90.3-1.1-1.71.51.7-1.9-1.3
Stereotopy head waving duration, day 71.01.23.00.60.8-0.10.60.6-0.9-0.8-1.2-0.80.5-0.8-1.71.61.6-1.7-1.5
Locomotion velocity, session 81.01.23.30.50.91.30.41.30.20.3-1.2-0.91.50.6-1.41.81.3-1.0-1.6
Locomotion distance, session 80.91.33.10.10.81.80.41.50.50.7-1.2-1.21.40.8-1.31.51.2-0.9-1.3
Degree of sensitization distance1.21.24.6-2.01.10.31.30.71.51.4-0.6-0.70.71.12.10.00.10.30.8
Degree of sensitization stereotypy1.01.12.90.60.70.10.50.6-0.8-0.7-1.1-0.80.6-0.6-1.71.51.5-1.6-1.5
Conditioned locomotion0.81.02.90.1-1.00.2-0.8-0.90.30.51.20.8-0.60.41.0-1.5-1.51.41.7
Cocaine response after cond. corrected0.81.12.8-1.61.6-0.21.71.01.00.8-1.2-1.01.00.61.31.01.0-0.50.0
Cocaine response after cond. not corrected1.21.74.9-2.21.8-0.32.10.91.51.3-1.2-1.00.90.92.20.60.8-0.20.8
Cocaine response before conditioning1.11.33.3-1.81.10.71.20.81.71.8-0.6-0.80.81.41.80.10.10.51.1
Saline control response0.91.34.10.4-0.1-2.00.1-0.6-1.7-1.9-0.2-0.0-1.2-2.0-1.00.00.7-1.4-0.9
Bone: connectivity density0.71.15.91.8-0.90.5-1.0-0.3-1.3-0.90.2-0.0-0.4-0.8-2.40.20.2-0.7-1.5
Bone: cortical apparent density2.03.25.71.8-2.0-1.7-1.9-2.4-1.5-1.72.22.4-1.9-1.3-0.3-1.9-1.91.41.0
Bone: cortical area0.40.73.6-0.90.3-1.90.8-0.5-0.9-0.9-0.2-0.3-1.1-1.40.6-0.40.4-0.9-0.2
Bone: cortical porosity0.40.41.40.2-0.7-0.7-0.3-0.7-0.8-0.50.40.0-1.2-0.90.1-1.0-0.4-0.20.6
Bone: cortical porosity0.40.41.40.3-0.7-0.7-0.3-0.6-1.0-0.70.3-0.1-1.2-1.1-0.2-0.8-0.2-0.50.2
Bone: cortical thickness2.44.18.61.1-2.0-2.9-1.4-2.7-2.1-2.32.12.1-2.8-2.30.2-2.3-1.70.81.2
Bone: cortical thickness1.11.33.6-0.2-0.7-1.9-0.2-1.5-0.6-0.81.11.1-1.5-0.91.5-1.6-1.10.81.2
Bone: cortical tissue density1.82.95.31.8-2.0-1.5-1.9-2.3-1.4-1.62.12.3-1.7-1.2-0.4-1.8-1.91.40.9
Condit. Reinf. active minus inactive responses1.21.45.90.40.32.4-0.41.11.61.6-0.10.01.82.1-0.00.8-0.21.00.6
Condit. Reinf. active-inactive response ratio0.30.31.7-0.50.4-0.40.40.10.60.20.10.30.30.41.30.0-0.20.51.0
Condit. Reinf. active responses1.92.410.80.50.73.3-0.11.81.71.9-0.8-0.72.52.4-0.91.70.50.4-0.3
Condit. Reinf. inactive responses1.41.98.30.60.52.9-0.11.50.91.4-0.9-1.01.91.6-1.71.60.8-0.3-1.3
Incentive salience index mean1.52.06.6-0.41.02.60.71.81.82.0-1.1-1.31.92.00.01.20.7-0.1-0.1
Condit. Reinf. lever presses1.62.36.8-1.01.41.91.52.01.21.9-1.9-2.61.21.1-0.21.11.5-1.4-1.0
Condit. Reinf. active minus inactive responses0.60.92.6-0.71.4-0.11.20.90.30.0-1.1-0.51.20.3-0.01.61.3-0.7-1.4
Condit. Reinf. active-inactive response ratio0.40.61.6-0.10.7-1.30.8-0.1-0.8-1.1-0.6-0.1-0.1-1.0-0.50.91.0-1.0-1.2
Condit. Reinf. active responses1.21.73.6-1.51.61.11.21.51.81.5-1.1-0.71.91.71.01.40.80.1-0.4
Condit. Reinf. inactive responses1.52.26.2-1.40.92.20.71.42.42.5-0.6-0.71.72.41.40.5-0.11.01.1
Condit. Reinf. lever presses1.01.53.8-1.81.8-0.91.91.00.50.2-1.5-1.30.6-0.11.01.11.5-1.3-0.7
Condit. Reinf. lever reinforcers received1.01.32.8-1.41.40.91.11.21.61.4-0.9-0.51.71.61.11.20.60.3-0.2
Conditioned reinforcement - actives0.10.51.7-1.30.8-0.30.90.50.70.7-0.8-1.0-0.10.00.30.00.5-0.6-0.7
Conditioned reinforcement - inactives0.00.10.3-0.50.20.3-0.00.30.60.5-0.1-0.10.20.40.10.0-0.00.20.0
Conditioned locomotion0.40.61.5-0.2-0.7-0.5-0.5-0.90.20.01.00.8-0.70.00.9-1.2-1.11.01.2
Patch foraging indifference point 0 sec0.10.30.8-0.20.8-0.30.70.40.0-0.2-0.7-0.40.4-0.2-0.30.90.9-0.7-0.8
Patch foraging indifference point AUC0.51.13.10.8-1.01.8-1.3-0.10.91.20.90.50.31.3-0.1-0.8-1.31.51.2
Delay disc. indifference point, 0s delay0.70.84.20.8-0.02.1-0.60.70.80.9-0.10.11.41.4-1.10.8-0.00.6-0.3
Delay disc. indifference point, 16s delay0.10.21.1-0.4-0.0-0.30.2-0.20.00.10.30.4-0.10.11.0-0.4-0.40.50.4
Delay disc. indifference point, 2s delay0.60.71.7-0.70.71.00.50.81.21.1-0.4-0.21.21.30.80.70.10.50.0
Delay disc. indifference point, 24s delay0.10.10.3-0.20.20.40.30.20.20.4-0.1-0.10.40.40.40.20.00.2-0.5
Delay disc. indifference point, 4s delay1.01.02.2-0.61.11.31.01.30.91.1-1.0-0.91.51.20.11.30.8-0.3-1.2
Delay disc. indifference point, 8s delay2.03.46.0-2.02.12.01.82.22.42.4-1.7-1.62.32.31.51.61.1-0.1-0.7
Indifference point function ln k0.41.22.6-0.81.3-1.41.50.4-0.6-0.9-1.2-0.80.1-1.0-0.11.21.5-1.5-1.6
Indifference point function log k0.41.22.6-0.81.3-1.41.50.4-0.6-0.9-1.2-0.80.1-1.0-0.11.21.5-1.5-1.6
Patch foraging total patch changes 0 sec0.00.10.3-0.20.5-0.40.50.20.0-0.2-0.4-0.10.2-0.10.00.50.5-0.4-0.5
Patch foraging total patch changes 12 sec0.40.51.30.9-1.10.5-1.1-0.7-0.10.10.90.6-0.40.2-0.4-0.9-1.00.80.8
Patch foraging total patch changes 18 sec0.10.30.70.2-0.5-0.7-0.5-0.7-0.2-0.40.60.5-0.8-0.40.3-0.8-0.60.30.8
Patch foraging total patch changes 24 sec0.20.61.51.1-0.51.2-1.1-0.00.50.30.50.90.90.9-0.80.4-0.51.00.5
Patch foraging total patch changes 6 sec0.30.52.41.4-0.61.2-1.0-0.1-0.1-0.10.30.50.60.5-1.50.5-0.20.3-0.4
Patch foraging time to switch 0 sec0.20.61.70.6-0.7-0.8-0.4-0.6-1.3-1.10.20.0-1.1-1.3-0.9-0.50.0-0.7-0.3
Patch foraging water rate 0 sec0.31.02.3-1.21.30.31.10.81.41.0-0.7-0.21.41.21.51.00.40.40.2
Patch foraging water rate 12 sec0.31.33.6-0.91.70.51.31.11.10.7-1.4-0.71.81.00.51.91.3-0.5-0.7
Patch foraging water rate 18 sec0.30.62.40.5-0.4-0.2-0.6-0.90.1-0.21.01.60.30.40.5-0.2-0.91.41.1
Patch foraging water rate 24 sec0.10.20.60.8-0.1-0.1-0.2-0.5-0.4-0.40.20.70.3-0.0-0.40.4-0.00.30.0
Patch foraging water rate 6 sec1.01.53.3-1.01.70.71.31.51.10.8-1.4-0.91.71.00.31.81.4-0.6-0.9
Seeking ratio, delayed vs. immediate footshock3.55.08.2-2.32.71.92.32.92.01.9-2.7-2.72.51.70.52.62.4-1.7-2.1
Distance traveled before self-admin0.92.03.8-0.81.70.81.51.60.60.7-1.9-1.71.40.5-0.61.91.9-1.6-1.8
Distance traveled after self-admin1.52.74.9-2.12.20.32.11.91.31.2-2.2-2.21.20.60.81.61.9-1.6-1.6
Extensor digitorum longus weight1.14.59.4-1.82.03.11.42.82.72.7-1.9-1.73.12.90.22.31.3-0.1-0.7
Bone: elastic displacement0.70.92.70.6-1.00.3-1.2-0.90.30.21.31.3-0.20.50.2-1.0-1.51.61.1
Bone: elastic work0.30.41.00.5-0.7-0.4-0.7-0.9-0.2-0.30.91.0-0.5-0.10.3-0.8-0.90.90.7
Bone: endosteal estimation3.07.413.2-3.03.51.43.53.31.82.0-3.6-3.62.41.30.63.03.3-2.7-2.2
Bone: endosteal perimeter1.74.37.6-2.42.51.32.62.51.51.8-2.6-2.81.91.20.52.12.3-1.8-1.8
Epididymis fat weight1.05.010.83.0-3.10.9-3.3-2.4-0.9-0.52.92.7-1.10.1-1.6-2.1-2.92.61.7
Delta time in closed arm before/after self-admin1.41.32.20.5-1.2-0.9-1.0-1.4-0.5-0.61.51.5-1.1-0.50.9-1.5-1.51.31.2
Delta time in open arm before/after self-admin1.92.27.21.5-0.4-1.4-0.4-0.4-2.2-2.2-0.2-0.0-1.0-2.2-2.70.51.0-1.7-1.8
Diff in mean of infusions in LGA sessions1.32.45.6-2.42.00.52.11.81.81.6-1.8-2.01.01.01.51.01.3-1.0-0.4
Delay discount exponential model param1.11.52.61.3-1.4-1.2-1.3-1.4-1.4-1.51.11.0-1.6-1.5-1.0-1.2-0.80.20.9
Extinction: sum of active levers before priming0.20.41.0-0.70.7-0.30.80.6-0.00.0-0.8-0.90.1-0.30.10.50.9-1.0-0.5
Active lever presses in extinction session 61.61.62.8-0.81.50.71.41.60.80.7-1.7-1.51.30.5-0.41.71.6-1.3-1.4
Bone: final force0.10.20.7-0.80.6-0.30.90.30.30.3-0.5-0.50.10.10.70.20.4-0.3-0.2
Bone: final moment0.10.20.7-0.50.2-0.80.6-0.20.0-0.1-0.0-0.0-0.4-0.30.8-0.3-0.0-0.10.2
Food consumed during 24 hour testing period2.03.911.3-3.42.8-0.33.11.91.91.7-2.1-2.01.31.12.81.21.6-1.0-0.3
Glucose0.00.10.40.6-0.1-0.2-0.3-0.2-0.3-0.40.10.2-0.1-0.2-0.40.10.0-0.0-0.2
Heart weight0.81.33.9-0.60.72.00.11.21.81.7-0.5-0.31.72.00.00.90.10.7-0.3
Delay discount hyperbolic model param1.21.52.71.3-1.4-1.3-1.3-1.4-1.5-1.61.11.0-1.6-1.6-1.1-1.1-0.70.00.7
Intermittent access intake day 1-15 change0.42.16.7-1.61.41.70.91.72.62.3-1.2-1.21.52.00.70.80.50.3-0.1
Intermittent access intake escalation0.42.06.2-1.41.31.80.81.62.52.3-1.1-1.11.62.00.50.80.40.3-0.1
Intermittent access intake escalation 22.13.57.5-1.92.12.01.52.32.72.5-1.9-1.92.22.20.51.61.3-0.4-0.7
Intermitt. access day 1 inactive lever presses0.10.91.70.4-0.9-1.1-0.5-1.1-1.0-1.01.00.9-1.1-0.90.8-1.1-0.80.41.3
Intermitt. access day 15 inactive lever presses0.10.72.20.8-1.00.9-0.8-0.20.30.31.10.90.10.70.2-0.7-1.21.31.5
Intermitt. access escalation Index0.30.84.3-1.30.9-0.50.9-0.21.31.3-0.3-0.10.20.82.1-0.3-0.20.70.9
Intermittent access day 1 total infusions0.20.51.70.0-0.7-1.0-0.2-1.0-0.8-0.50.60.2-1.3-0.90.4-1.2-0.60.00.2
Intermittent access day 15 total infusions0.10.20.8-0.70.20.20.30.10.70.9-0.2-0.5-0.20.40.6-0.5-0.20.10.2
Intermittent access terminal intake (last 3 days)0.40.62.2-1.50.70.30.80.61.21.2-0.6-0.90.20.71.2-0.20.2-0.10.4
Intermittent access total infusions0.20.30.7-0.80.2-0.70.6-0.2-0.10.2-0.3-0.7-0.8-0.50.7-0.60.1-0.50.1
Intermittent access day 1 locomotion0.61.12.90.3-1.2-0.7-0.8-1.4-0.4-0.21.31.0-1.2-0.40.9-1.7-1.41.10.9
Intermittent access day 15 total locomotion0.10.51.1-0.2-0.6-0.7-0.5-0.8-0.4-0.40.70.4-0.9-0.50.9-1.0-0.70.41.0
Intermittent access total locomotion0.20.31.5-1.10.4-0.50.60.10.20.2-0.3-0.4-0.2-0.11.2-0.20.2-0.30.3
Intermittent access standard deviation0.10.31.0-0.70.20.80.10.61.01.0-0.2-0.60.20.80.6-0.3-0.10.20.6
Left kidney weight0.32.17.6-2.31.20.41.10.82.41.9-0.4-0.30.91.82.8-0.1-0.41.11.5
Right kidney weight0.21.44.3-1.50.91.00.50.92.11.7-0.3-0.21.21.81.70.3-0.21.01.0
Cocaine induced anxiety0.00.10.4-0.00.0-0.20.10.1-0.3-0.1-0.3-0.5-0.4-0.4-0.5-0.10.3-0.6-0.6
Post-drug Anxiety0.20.21.50.7-0.40.1-0.4-0.1-0.7-0.50.0-0.0-0.2-0.5-1.20.10.1-0.4-0.4
Baseline Anxiety0.61.03.11.8-1.10.2-1.4-0.8-0.8-0.91.11.4-0.0-0.2-1.5-0.0-0.70.80.3
Tail length0.10.82.90.3-0.41.7-0.60.11.21.20.50.40.81.50.0-0.1-0.81.30.0
Length with tail0.41.75.4-0.80.31.9-0.10.62.32.10.10.21.42.30.90.1-0.81.70.6
Length without tail0.94.512.9-2.92.11.51.91.83.63.1-1.2-1.02.22.92.90.90.21.11.0
Times rat made contact with spout1.11.33.5-1.91.6-0.31.91.01.00.9-1.2-1.10.70.51.90.71.0-0.60.1
Lifetime Intake0.20.20.8-0.5-0.0-0.60.4-0.3-0.30.0-0.1-0.6-0.9-0.60.4-0.70.0-0.5-0.0
Liver weight, left0.30.51.7-1.00.50.50.30.41.31.2-0.10.00.61.11.0-0.1-0.40.80.1
Liver weight, right0.71.33.8-1.30.71.10.60.92.01.8-0.2-0.11.21.81.60.1-0.41.10.7
Locomotor activity0.10.20.7-0.50.40.00.7-0.10.50.8-0.2-0.30.10.40.8-0.1-0.00.30.5
Locomotor testing distance0.00.10.4-0.20.3-0.50.6-0.30.10.1-0.10.10.0-0.00.60.10.10.10.6
Locomotor testing rearing0.00.10.30.30.1-0.30.3-0.4-0.00.00.10.40.20.10.30.2-0.10.30.5
Locomotion in novel chamber0.10.10.3-0.10.1-0.50.2-0.1-0.5-0.5-0.2-0.2-0.3-0.60.40.00.3-0.5-0.5
Locomotion in novel chamber post-restriction0.10.30.80.4-0.70.2-0.9-0.20.3-0.00.70.8-0.20.2-0.3-0.6-0.90.90.6
Fecal boli incidents, locomotor time 10.71.85.1-1.61.11.81.21.32.02.3-0.9-1.31.41.91.40.40.30.30.3
Change in fecal boli incidents, locomotor task1.92.04.70.10.7-2.10.7-0.0-1.7-2.0-0.9-0.6-0.8-2.2-1.20.91.6-2.2-1.7
Time >=10cm from walls, locomotor time 10.50.71.8-0.80.90.60.90.90.40.7-1.1-1.30.50.3-0.00.71.0-0.9-0.9
Bouts of movement, locomotor time 10.40.51.6-0.60.31.10.50.71.11.3-0.1-0.20.81.20.80.1-0.20.60.2
Total resting periods, locomotor time 10.30.41.0-0.60.30.70.60.50.91.0-0.1-0.20.60.90.90.0-0.10.40.2
Rest time, locomotor task time 10.81.27.5-1.60.7-0.50.90.11.41.00.10.30.40.92.7-0.4-0.51.11.6
Distance moved, locomotor task time 10.20.62.51.6-1.00.7-1.4-0.5-0.4-0.30.60.6-0.00.0-1.6-0.1-0.50.4-0.3
Vertical activity count, locomotor time 10.00.31.31.1-0.70.5-0.9-0.3-0.5-0.20.40.3-0.1-0.1-1.1-0.2-0.30.2-0.2
Time >=10cm from walls, locomotor time 20.10.31.4-0.6-0.1-0.6-0.1-0.30.40.20.40.2-0.6-0.01.2-0.9-0.60.50.9
Bouts of movement, locomotor time 20.31.02.60.8-1.11.3-1.3-0.40.60.61.21.00.21.00.0-0.8-1.41.61.2
Total resting periods, locomotor time 20.20.71.80.7-0.91.1-1.0-0.20.50.60.90.80.20.90.1-0.6-1.21.31.0
Rest time, locomotor task time 20.81.42.50.5-1.2-1.6-0.8-1.4-0.9-1.11.31.3-1.5-1.10.4-1.5-1.20.71.3
Distance moved, locomotor task time 20.50.72.60.60.31.6-0.30.80.60.7-0.4-0.21.31.0-1.01.10.40.1-0.9
Vertical activity count, locomotor time 20.10.30.6-0.30.40.80.20.60.70.8-0.5-0.50.70.70.10.40.30.0-0.3
Light reinforcement 10.83.810.5-1.91.62.51.31.73.23.2-1.0-1.12.33.11.90.90.11.10.6
Light reinforcement 20.30.62.5-0.60.1-1.60.7-0.5-0.8-0.6-0.2-0.6-1.4-1.30.6-0.90.2-0.90.2
Bone: marrow area3.07.313.1-3.13.51.23.53.21.82.0-3.6-3.62.31.30.72.93.3-2.6-2.1
Bone: maximum diameter3.67.314.9-3.83.60.63.93.02.02.1-3.4-3.42.21.31.72.53.0-2.3-1.7
Bone: maximum force0.20.51.3-1.00.9-0.21.10.70.40.4-0.9-0.90.30.10.60.50.8-0.7-0.3
Bone: maximum moment0.10.20.8-0.80.6-0.60.90.20.10.1-0.5-0.6-0.2-0.30.70.10.5-0.50.1
Mean time between licks in bursts0.00.20.9-0.1-0.5-0.5-0.2-0.5-0.2-0.00.40.1-0.8-0.40.3-0.9-0.50.20.9
Mean num. licks in bursts0.41.02.20.2-0.8-1.2-0.7-1.2-0.3-0.71.31.5-0.9-0.41.1-1.2-1.31.21.2
Cd content in liver1.71.95.41.4-1.41.7-2.0-0.50.80.61.61.90.71.4-0.6-0.5-1.82.30.8
Co content in liver1.61.96.4-0.1-1.00.7-1.0-0.81.31.11.51.50.01.41.4-1.4-2.12.51.6
Cu content in liver0.10.10.2-0.40.10.00.10.10.40.30.1-0.0-0.00.20.5-0.3-0.20.30.4
Fe content in liver3.84.711.4-0.72.00.41.81.9-0.8-0.5-2.7-2.51.2-0.8-2.42.93.2-3.3-3.4
K content in liver0.00.00.10.00.00.1-0.10.40.1-0.2-0.00.10.20.0-0.30.30.1-0.1-0.1
Mg content in liver0.30.40.8-0.50.80.30.70.90.50.3-0.7-0.50.80.40.20.90.7-0.4-0.5
Mn content in liver0.91.04.0-0.4-0.1-2.00.6-0.6-1.2-1.1-0.1-0.5-1.7-1.70.5-0.90.2-1.1-0.0
Na content in liver1.82.14.3-0.31.21.11.11.7-0.00.2-1.8-2.01.10.0-1.51.82.0-2.1-1.9
Rb content in liver0.91.02.9-0.31.00.70.51.20.1-0.1-1.1-0.81.20.2-1.11.71.4-1.1-1.5
Se content in liver0.81.02.90.6-0.4-1.2-0.2-0.5-1.7-1.7-0.0-0.0-1.0-1.7-1.30.00.5-1.2-0.9
Sr content in liver0.10.10.50.2-0.10.7-0.10.30.10.4-0.2-0.50.10.2-0.40.00.1-0.2-0.2
Zn content in liver0.91.12.20.7-1.3-0.4-1.3-1.2-0.3-0.51.51.4-0.9-0.30.2-1.4-1.51.30.5
Bone: minimum diameter0.20.31.5-1.20.4-0.80.8-0.10.20.2-0.2-0.3-0.5-0.21.1-0.50.0-0.10.3
Time in familiar zone, hab. session 11.31.43.3-1.31.40.81.51.40.81.1-1.6-1.81.00.70.31.11.4-1.2-0.7
Time in novel zone, hab. session 11.41.64.20.8-1.1-1.1-1.1-1.4-0.3-0.81.62.0-0.8-0.30.7-1.2-1.61.71.6
Total zone transitions, hab. session 10.91.34.62.1-1.51.6-1.9-0.3-0.3-0.11.00.80.10.4-2.1-0.3-0.90.8-0.4
Total locomotion distance, hab. session 11.52.17.72.8-1.91.6-2.4-0.9-0.5-0.31.51.4-0.00.3-2.2-0.5-1.31.2-0.3
Locomotion velocity, hab. session 10.91.35.22.3-1.51.4-1.9-0.6-0.5-0.21.00.8-0.00.2-2.1-0.3-0.80.7-0.6
Time in familiar zone, hab. session 20.10.10.3-0.20.5-0.30.60.30.0-0.2-0.4-0.20.3-0.10.30.50.5-0.3-0.0
Time in novel zone, hab. session 20.10.10.4-0.1-0.1-0.60.1-0.3-0.3-0.30.10.1-0.5-0.40.3-0.4-0.1-0.00.0
Total zone transitions, hab. session 21.21.58.21.5-0.82.9-1.40.70.81.10.30.21.21.6-1.80.4-0.50.9-0.1
Total locomotion distance, hab. session 21.31.77.91.8-1.22.8-1.80.20.61.10.80.50.91.5-1.8-0.1-1.01.20.2
Locomotion velocity, hab. session 21.21.56.11.9-1.42.5-1.9-0.10.30.90.90.50.41.2-1.8-0.4-1.11.10.3
Novel to familiar place preference ratio0.30.30.8-0.80.60.40.50.60.90.8-0.4-0.40.60.80.60.20.20.10.3
Novelty place preference0.60.71.6-1.31.10.41.00.91.21.1-0.7-0.70.81.01.10.40.40.00.3
Time in novel zone, NPP test0.81.02.4-1.61.40.11.41.01.31.1-1.0-0.80.90.91.40.70.6-0.10.2
Total zone transitions, NPP test0.60.84.20.9-0.22.1-0.70.80.70.7-0.1-0.11.21.1-1.30.80.10.3-0.8
Total locomotion distance, NPP test0.81.16.71.1-0.42.6-1.00.70.71.10.0-0.11.21.4-1.60.6-0.10.5-0.7
Locomotion velocity, NPP test0.91.36.81.7-0.92.6-1.50.40.20.70.2-0.00.91.0-2.30.4-0.30.3-0.9
Intraocular pressure0.20.31.1-0.40.10.0-0.3-0.10.80.30.40.80.50.70.7-0.0-0.61.10.8
Delta distance traveled before/after self-admin0.60.73.9-1.40.4-0.40.40.11.20.80.10.1-0.10.62.0-0.6-0.50.80.7
Delta ambulatory time before/after self-admin0.40.74.6-1.50.4-1.00.5-0.10.90.50.10.1-0.40.22.1-0.7-0.40.50.6
Parametrial fat weight0.92.24.61.4-2.00.3-2.0-1.7-0.20.11.91.6-1.10.1-0.3-1.9-2.11.81.4
Pavlov. Cond. lever latency2.12.75.81.1-1.4-2.4-1.2-2.3-1.5-2.01.82.3-1.7-1.60.4-1.4-1.41.11.0
Pavlov. Cond. magazine entry latency0.30.42.40.1-0.41.5-0.30.40.51.2-0.1-0.80.00.7-0.3-0.5-0.30.1-0.0
Pavlov. Cond. change in total contacts0.60.63.1-0.20.01.8-0.00.81.11.5-0.2-0.80.61.20.2-0.1-0.20.30.5
Pavlov. Cond. index score0.70.94.7-0.20.22.20.11.21.01.6-0.7-1.40.71.2-0.50.20.3-0.3-0.4
Pavlov. Cond. latency score0.81.04.4-0.30.32.10.21.31.01.6-0.8-1.50.81.2-0.50.40.5-0.4-0.4
Pavlov. Cond. lever contacts1.41.64.4-0.91.02.10.91.81.41.9-1.3-1.91.21.4-0.10.80.9-0.7-0.6
Pavlov. Cond. magazine entry number0.30.32.1-0.30.4-1.50.5-0.4-0.5-1.0-0.00.6-0.1-0.70.30.40.3-0.20.2
Pavlov. Cond. intertrial magazine entries0.80.93.40.90.61.3-0.11.00.30.0-0.7-0.11.60.7-1.51.80.9-0.4-0.7
Pavlov. Cond. lever-magazine prob. diff.0.91.15.5-0.20.22.30.21.31.01.7-0.8-1.60.81.3-0.50.30.4-0.4-0.5
Pavlov. Cond. response bias0.60.84.1-0.20.12.00.11.11.01.6-0.6-1.20.71.2-0.20.10.2-0.2-0.4
Pavlov. Cond. lever latency1.82.54.81.9-2.2-0.5-2.1-1.8-1.2-1.22.01.9-1.6-0.9-0.6-1.8-1.91.31.3
Pavlov. Cond. magazine entry latency0.91.23.60.8-0.8-1.4-0.4-1.1-1.8-1.50.30.0-1.6-1.9-1.0-0.70.1-1.0-0.7
Pavlov. Cond. change in total contacts0.10.30.5-0.70.7-0.10.70.40.10.2-0.6-0.50.40.10.10.60.6-0.5-0.7
Pavlov. Cond. index score0.50.82.0-0.71.0-0.31.10.7-0.2-0.1-1.2-1.20.2-0.4-0.30.91.3-1.4-1.2
Pavlov. Cond. latency score0.71.23.0-1.01.2-0.51.40.8-0.3-0.1-1.5-1.50.2-0.6-0.21.11.6-1.7-1.5
Pavlov. Cond. lever contacts1.72.44.8-1.92.20.42.11.71.11.1-2.0-1.91.40.80.71.71.8-1.3-1.2
Pavlov. Cond. magazine entry number0.81.02.5-0.4-0.01.0-0.30.21.51.20.50.60.81.61.1-0.3-0.91.61.5
Pavlov. Cond. intertrial magazine entries0.40.92.7-0.80.41.60.30.91.41.6-0.2-0.41.21.60.70.3-0.20.70.4
Pavlov. Cond. lever-magazine prob. diff.0.40.71.8-0.70.9-0.21.00.6-0.2-0.0-1.1-1.20.2-0.4-0.20.81.2-1.3-1.1
Pavlov. Cond. response bias0.40.61.2-0.50.90.20.90.70.00.2-1.0-1.00.5-0.0-0.41.01.1-1.1-1.1
Time in closed arm before self-admin0.81.43.3-1.11.40.71.41.30.60.9-1.6-1.80.80.4-0.11.21.5-1.4-1.2
Time in closed arm after self-admin0.20.20.40.5-0.70.0-0.6-0.7-0.3-0.10.70.5-0.4-0.00.1-0.7-0.70.60.3
Time in open arm before self-admin0.80.95.1-1.71.0-0.11.10.71.20.9-0.5-0.50.50.72.30.10.20.20.7
Time in open arm after self-admin1.71.95.6-0.71.3-1.21.40.9-0.8-0.9-1.6-1.5-0.1-1.3-0.71.32.0-2.4-2.0
Bone: periosteal estimation1.74.18.8-2.82.70.13.02.21.11.2-2.7-2.71.40.51.01.92.5-2.1-1.6
Bone: periosteal perimeter0.91.93.9-1.61.7-0.42.01.30.20.2-1.8-1.80.6-0.30.21.31.9-1.9-1.6
Bone: post-yield work2.03.56.5-1.52.41.02.32.31.11.3-2.5-2.51.80.90.12.32.4-1.9-1.3
Progressive ratio test 1 active lever presses0.20.42.0-0.90.1-0.90.6-0.40.00.30.0-0.3-0.8-0.31.4-0.9-0.2-0.00.5
Progressive ratio test 1 breakpoint0.30.42.3-1.10.2-0.90.7-0.30.10.3-0.1-0.4-0.8-0.31.5-0.9-0.2-0.10.5
Progressive ratio test 1 inactive lever presses0.10.41.0-0.2-0.4-0.80.1-0.9-0.4-0.20.50.3-0.9-0.50.8-1.0-0.60.31.0
Progressive ratio test 2 active lever presses0.20.31.0-1.00.3-0.20.50.10.60.7-0.3-0.6-0.30.21.0-0.5-0.0-0.10.4
Progressive ratio test 2 breakpoint0.20.20.7-0.80.2-0.20.40.00.50.7-0.2-0.5-0.30.10.8-0.5-0.1-0.00.4
Progressive ratio test 2 inactive lever presses0.10.31.0-0.1-0.5-0.8-0.0-0.7-0.5-0.30.40.1-1.0-0.60.5-0.9-0.40.00.8
Incentive Sensitization - Responses0.10.20.5-0.70.20.10.20.10.60.6-0.1-0.4-0.10.30.7-0.4-0.10.10.7
Incentive Sensitization - Breakpoint0.10.20.7-0.4-0.10.3-0.1-0.10.60.70.1-0.1-0.00.50.6-0.5-0.40.40.9
Sum of active levers in priming session hrs 5-60.80.81.5-0.91.2-0.21.01.10.4-0.0-1.2-0.90.6-0.1-0.11.21.2-1.1-1.2
Progressive ratio0.30.92.4-1.10.71.20.70.91.51.6-0.6-0.80.91.31.20.20.10.31.0
Food seeking constrained by brief footshock3.13.97.6-2.22.81.02.32.42.11.6-2.3-1.82.41.61.12.42.0-1.0-1.1
Seeking ratio, punishment vs. effort0.40.93.4-0.21.0-0.10.70.8-0.1-0.4-1.0-0.50.9-0.2-0.71.51.3-1.1-1.8
Retroperitoneal fat weight1.67.115.82.9-3.40.9-4.0-2.5-0.1-0.23.63.5-1.10.7-0.7-2.8-3.83.82.7
Reaction time number correct0.20.83.80.30.50.50.40.8-0.2-0.1-0.9-0.80.6-0.1-1.41.21.1-1.1-1.9
Reaction time mean minus median0.21.12.00.9-1.4-0.8-1.4-1.2-0.6-0.81.41.3-1.2-0.7-0.3-1.4-1.31.00.6
Reaction time mean minus median AUC0.10.81.50.8-1.1-1.0-1.0-1.0-0.8-0.91.00.9-1.2-0.9-0.6-1.0-0.80.40.1
Reaction time num false alarms0.50.92.41.5-1.2-0.5-1.1-1.0-1.2-1.20.91.0-0.8-0.9-1.1-0.5-0.60.20.4
Reaction time num false alarms AUC0.51.12.91.7-1.2-0.6-1.1-1.1-1.4-1.40.91.0-0.9-1.1-1.4-0.5-0.50.10.1
Reaction time trials correct on left0.20.83.80.30.50.50.40.8-0.2-0.1-0.9-0.80.6-0.1-1.41.21.1-1.1-1.9
Reaction time trials on left0.20.84.00.40.40.50.30.7-0.3-0.2-0.9-0.70.5-0.2-1.51.11.1-1.1-2.0
Reaction time mean0.51.12.70.6-1.2-1.4-0.9-1.3-1.0-1.01.10.9-1.7-1.2-0.2-1.5-1.00.40.4
Reaction time mean AUC0.30.71.80.5-0.9-1.2-0.7-1.0-0.9-0.80.80.6-1.4-1.1-0.3-1.1-0.70.20.0
Median of all reaction times0.71.12.90.5-1.1-1.5-0.7-1.3-1.1-1.01.00.7-1.7-1.3-0.1-1.5-0.90.20.3
Reaction time omissions1.83.07.12.7-2.2-0.8-2.1-2.1-2.1-1.81.71.7-1.6-1.6-2.0-1.2-1.30.6-0.3
Reaction time false alarm rate1.01.42.31.5-1.5-0.8-1.3-1.5-1.2-1.21.41.5-1.1-0.9-0.4-1.1-1.20.81.3
Reaction time premature initiation rate0.20.31.0-0.20.10.6-0.10.00.90.80.20.40.61.00.50.0-0.51.00.4
Reaction time premature initiations0.10.30.7-0.10.30.80.10.40.80.7-0.20.10.80.9-0.20.50.00.4-0.5
Std. dev. reaction times0.51.62.71.2-1.6-1.2-1.4-1.6-1.2-1.21.41.3-1.6-1.2-0.8-1.5-1.30.60.3
Reaction time trials completed0.20.84.00.40.40.50.30.7-0.3-0.2-0.9-0.70.5-0.2-1.51.11.1-1.1-2.0
Reaction time trials AUC0.30.94.30.40.60.50.40.8-0.3-0.1-1.0-0.80.6-0.2-1.51.31.2-1.2-2.1
Run reversals in cocaine runway, females1.11.22.20.9-1.0-1.4-0.8-1.5-1.1-1.11.21.3-1.2-1.00.3-1.1-1.00.71.2
Run reversals in cocaine runway, males1.11.22.9-0.31.01.70.61.31.11.0-1.0-0.91.71.3-0.51.50.9-0.4-1.2
Latency to leave start box in cocaine runway0.30.51.50.00.40.10.40.5-0.5-0.3-0.8-0.90.1-0.5-0.90.71.0-1.2-1.0
Latency to leave start box in cocaine runway, F0.00.10.1-0.00.20.30.20.20.10.2-0.3-0.30.20.2-0.30.30.3-0.2-0.3
Latency to leave start box in cocaine runway, M0.60.62.00.30.2-0.40.20.4-0.9-0.9-0.6-0.7-0.2-1.0-1.10.61.0-1.4-0.9
Std. dev. time between licks in bursts0.61.22.5-0.40.81.60.71.50.61.1-1.2-1.51.00.7-0.91.01.1-1.0-1.4
Total sessions with >9 infusions0.20.21.1-0.80.4-0.10.70.20.20.5-0.4-0.8-0.20.01.0-0.20.2-0.40.1
Short access day 1 total inactive lever presses0.40.73.3-0.6-0.3-0.70.2-0.80.30.30.70.5-0.70.11.8-1.2-1.00.91.5
Short access day 10 total inactive lever presses0.00.20.70.1-0.30.3-0.3-0.20.40.30.40.40.00.40.2-0.4-0.60.70.8
Short access day 1 total infusions0.00.10.4-0.50.1-0.10.30.20.10.2-0.3-0.6-0.3-0.10.3-0.30.1-0.40.1
Short access day 10 total infusions0.61.03.2-0.2-0.3-1.70.5-0.8-1.5-1.1-0.1-0.6-1.6-1.8-0.0-0.80.3-1.2-0.4
Short access total infusions0.30.51.90.1-0.6-1.0-0.1-0.7-0.9-0.50.3-0.2-1.4-1.1-0.1-1.0-0.2-0.50.1
Short access day 1 locomotion0.50.82.1-1.20.70.90.50.91.41.4-0.4-0.60.81.21.30.20.00.40.1
Short access day 10 total locomotion0.10.41.3-0.90.6-0.50.80.5-0.4-0.4-0.7-0.8-0.0-0.60.60.40.9-1.1-0.6
Short access total locomotion0.20.32.2-1.00.2-0.70.6-0.1-0.2-0.0-0.1-0.5-0.6-0.41.5-0.60.0-0.40.3
One hour access (0.3 mA shock)0.10.10.4-0.4-0.1-0.5-0.0-0.3-0.10.00.1-0.1-0.7-0.30.4-0.6-0.2-0.00.3
Compulsive drug intake0.71.04.9-0.40.4-2.20.7-0.4-1.3-1.4-0.3-0.1-1.0-1.70.30.00.7-1.1-0.5
One hour access (shock baseline)0.00.10.6-0.2-0.10.8-0.10.30.40.6-0.2-0.7-0.10.3-0.2-0.2-0.0-0.2-0.1
Social response proportion1.01.34.00.2-0.8-2.0-0.4-1.9-1.2-1.21.01.0-1.6-1.40.5-1.4-0.90.40.4
Social responses0.10.10.3-0.2-0.1-0.10.1-0.40.10.40.1-0.2-0.4-0.00.5-0.6-0.30.20.1
Social time0.10.10.60.30.0-0.70.2-0.5-0.5-0.4-0.1-0.0-0.5-0.7-0.2-0.10.2-0.3-0.3
Soleus weight5.917.429.1-4.05.04.04.45.44.54.5-4.6-4.35.34.21.64.73.8-1.8-2.2
Bone: stiffness0.10.20.60.10.40.20.20.5-0.1-0.2-0.5-0.30.4-0.1-0.50.80.7-0.6-0.7
Tibialis anterior weight3.010.417.8-3.24.22.33.64.22.82.6-3.9-3.43.92.50.64.13.6-2.2-2.1
Time to tail flick, vehicle, before self-admin0.10.10.60.4-0.2-0.0-0.5-0.1-0.2-0.20.10.2-0.1-0.2-0.80.1-0.10.0-0.3
Time to tail flick, vehicle, after self-admin0.71.33.6-1.11.3-0.41.51.2-0.2-0.2-1.5-1.60.4-0.50.31.11.7-1.9-1.1
Time to tail flick, test, before self-admin0.60.71.70.3-0.61.2-0.70.00.80.80.70.60.41.10.3-0.5-1.01.31.3
Time to tail flick, test, after self-admin1.01.02.7-1.20.91.00.80.91.61.6-0.5-0.51.01.51.50.2-0.00.60.6
Delta time to tail flick, vehicle, before/after SA1.31.42.9-0.91.40.61.41.50.20.3-1.6-1.61.00.1-0.11.51.7-1.6-1.3
Delta time to tail flick, test, before/after SA0.70.82.1-1.41.3-1.11.50.40.20.1-1.1-1.00.0-0.31.20.51.0-1.0-0.6
Tibia length0.92.410.9-3.31.6-0.92.30.61.41.4-1.0-1.4-0.10.53.1-0.50.4-0.21.4
Ambulatory time before self-admin0.41.32.2-0.21.11.01.01.30.20.5-1.4-1.51.00.3-1.01.51.5-1.4-1.5
Ambulatory time after self-admin1.42.34.3-2.12.1-0.12.11.61.00.9-2.0-2.00.90.30.91.31.8-1.6-1.4
Bone: tissue strength0.60.61.30.8-0.7-1.1-0.6-1.1-0.8-1.00.70.9-0.9-0.9-0.1-0.7-0.50.30.5
Total heroin consumption1.21.42.6-1.51.40.91.21.61.61.2-1.2-1.01.31.20.81.10.9-0.3-0.7
Bone: trabecular number0.30.62.60.8-0.11.0-0.20.3-0.50.1-0.5-0.80.2-0.1-1.60.50.6-0.9-1.5
Bone: trabecular spacing1.52.24.21.2-1.8-0.4-1.9-1.6-0.4-0.62.02.1-1.1-0.20.0-1.7-2.01.91.8
Bone: trabecular thickness0.10.20.8-0.40.0-0.90.2-0.5-0.0-0.10.20.3-0.5-0.30.9-0.5-0.30.20.5
Bone: trabecular tissue density0.40.72.0-0.6-0.3-1.3-0.1-0.90.1-0.40.80.9-0.8-0.31.4-1.0-0.90.81.4
Water consumed over 24 hours1.12.04.9-2.22.00.22.21.51.31.3-1.6-1.61.10.91.71.11.3-0.8-0.2
Number of responses in last shaping day2.12.85.5-2.31.91.21.81.82.22.2-1.6-1.91.31.72.20.70.9-0.40.1