Hub : Genes

Scg3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Scg3 0.16 0.08 1.1e-07 0.03 0.08 0.08 0.08 6.8e-04 4.0e-08 1.1e-07 8.7e-08
2 IL gene expression Scg3 0.22 0.11 3.8e-04 0.09 0.1 0.07 0.09 3.9e-03 2.7e-03 9.5e-03 4.3e-03
3 Adipose mRNA stability Scg3 0.05 0.04 9.2e-03 0 0 -0 0 3.5e-01 3.6e-01 7.8e-01 2.7e-01
4 OFC gene expression Scg3 0.35 0.13 1.0e-07 0.28 0.32 0.3 0.32 1.9e-07 2.2e-08 7.4e-08 2.3e-08
5 PL gene expression Scg3 0.13 0.06 2.8e-10 0.08 0.08 0.07 0.07 6.3e-09 1.8e-09 1.9e-08 1.7e-08
6 BLA mRNA stability Scg3 0.08 0.05 9.9e-04 0.03 0.05 0.01 0.03 9.0e-03 1.0e-03 6.0e-02 8.4e-03
7 PL mRNA stability Scg3 0.09 0.05 4.1e-07 0.04 0.05 0.04 0.06 5.4e-05 2.6e-06 7.4e-05 1.1e-06
8 NAcc mRNA stability Scg3 0.02 0.02 1.4e-03 0.02 0.02 0.02 0.02 9.2e-04 8.8e-04 1.1e-03 1.5e-03
9 NAcc gene expression Scg3 0.11 0.05 3.3e-08 0.04 0.07 0.06 0.06 3.3e-05 6.9e-09 4.7e-08 5.7e-08
10 Brain mRNA stability Scg3 0.2 0.08 0.0e+00 0.17 0.24 0.23 0.22 1.6e-15 1.0e-21 9.2e-21 2.2e-20
11 BLA gene expression Scg3 0.11 0.06 4.1e-03 0.04 0.04 0.03 0.03 2.0e-03 3.0e-03 8.6e-03 6.0e-03
12 Eye gene expression Scg3 0.55 0.16 4.1e-05 0.11 0.16 0.08 0.11 9.6e-03 2.3e-03 2.6e-02 9.1e-03
13 Adipose gene expression Scg3 0.04 0.03 3.3e-03 0.02 0.01 0.01 0.01 1.7e-03 4.0e-02 4.4e-02 1.3e-02
14 Liver gene expression Scg3 0.02 0.01 4.8e-03 -0 0 -0 -0 5.0e-01 1.9e-01 8.2e-01 1.0e+00
15 pVTA gene expression Scg3 0.1 0.06 2.9e-04 0.12 0.05 0.14 0.09 6.1e-06 4.7e-03 1.1e-06 8.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.10.21.1-0.00.10.2-0.1-0.1-0.2-0.4-0.3-0.4-0.40.50.3-0.60.5-1.0
Area under the delay curve1.51.63.21.41.5-1.51.41.6-0.9-1.2-1.31.8-1.0-1.11.01.20.7-1.1
BMI with tail2.06.419.62.12.8-2.53.22.7-1.6-2.0-1.83.8-1.4-4.40.83.40.51.2
BMI without tail1.42.88.32.71.2-2.90.82.50.0-0.6-0.82.8-0.4-2.61.20.80.10.9
Body weight1.98.128.12.92.7-3.73.13.2-1.0-1.6-1.64.5-1.0-5.30.63.8-0.01.6
Weight adjusted by age2.02.23.31.61.8-1.61.71.7-1.3-1.6-1.81.4-1.6-0.91.31.31.3-1.3
Bone surface1.42.44.71.01.9-0.51.41.4-1.9-2.1-2.10.8-2.2-0.02.0-0.42.2-1.0
Bone volume0.61.12.00.71.3-0.41.11.0-1.3-1.4-1.40.7-1.4-0.31.2-0.11.3-0.8
Breakpoint value in progressive ratio session1.01.12.41.01.3-0.61.11.1-1.1-1.5-1.40.8-1.3-0.71.10.21.20.4
Number of licking bursts1.82.24.21.01.9-0.51.71.3-1.8-2.0-2.00.9-2.0-0.51.50.31.90.0
Context. condit. distance diff. score0.40.51.5-0.40.90.51.00.2-1.2-0.9-0.90.1-1.00.10.60.31.0-0.6
Locomotion velocity, session 10.60.61.71.10.7-1.30.51.2-0.2-0.2-0.51.3-0.3-1.00.60.50.10.4
Locomotion distance, session 10.50.73.11.3-0.6-1.0-1.10.40.9-0.20.1-0.20.10.50.5-1.70.0-0.9
Locomotion velocity, session 20.80.92.21.40.9-1.40.51.5-0.5-0.7-1.01.2-0.9-0.61.20.00.80.0
Locomotion distance, session 20.91.36.12.5-0.2-2.4-0.81.51.1-0.2-0.11.10.1-0.70.8-1.1-0.20.1
Locomotion velocity, session 31.51.77.40.70.20.0-0.80.5-0.5-0.7-1.0-0.8-1.32.01.9-2.71.7-1.4
Locomotion distance, session 31.51.78.60.2-1.30.4-2.1-0.51.00.60.5-1.50.32.20.7-2.90.2-0.8
Stereotopy head waving bouts, day 31.11.34.7-2.00.02.20.3-1.5-1.0-0.4-0.2-1.7-0.51.6-0.4-0.20.7-0.9
Stereotopy head waving duration, day 30.91.14.5-2.10.42.10.8-1.2-1.3-0.1-0.2-1.0-0.50.8-0.40.60.6-0.6
Locomotion velocity, session 70.20.21.0-0.0-0.20.1-0.4-0.10.0-0.1-0.1-0.6-0.21.00.3-0.80.4-0.8
Locomotion distance, session 70.20.30.80.70.3-0.4-0.10.6-0.3-0.6-0.60.1-0.60.40.9-0.70.7-0.2
Stereotopy head waving bouts, day 71.11.23.4-0.30.40.9-0.30.1-1.0-0.4-0.9-0.8-1.21.81.6-1.81.6-1.1
Stereotopy head waving duration, day 71.01.23.10.10.60.5-0.10.5-1.1-0.6-1.1-0.4-1.41.41.8-1.71.7-1.0
Locomotion velocity, session 81.01.23.91.40.7-1.1-0.11.4-0.6-0.6-1.10.6-1.20.42.0-1.51.4-0.7
Locomotion distance, session 80.91.43.01.70.7-1.30.11.3-0.4-1.3-1.20.5-1.20.41.6-1.31.3-1.5
Degree of sensitization distance1.21.24.10.21.3-0.51.80.7-1.0-0.9-0.81.2-0.6-1.6-0.12.00.20.8
Degree of sensitization stereotypy0.90.92.90.20.50.3-0.30.5-0.8-0.5-0.9-0.3-1.21.31.7-1.71.5-0.8
Conditioned locomotion0.60.82.10.3-0.8-0.7-0.4-0.31.30.71.00.21.2-0.8-1.30.8-1.40.0
Cocaine response after cond. corrected1.11.33.1-0.21.60.11.80.8-1.7-1.0-1.21.1-1.2-1.00.71.41.00.1
Cocaine response after cond. not corrected1.71.95.7-0.51.90.22.40.7-1.9-1.1-1.31.3-1.2-1.60.32.20.80.9
Cocaine response before conditioning1.01.23.00.61.2-0.81.60.8-0.8-0.9-0.81.3-0.6-1.7-0.01.70.21.3
Saline control response1.01.35.6-2.1-0.12.40.1-1.4-1.0-0.1-0.1-1.6-0.41.5-0.2-0.50.7-1.0
Bone: connectivity density0.71.04.60.1-1.00.4-1.4-0.70.70.10.3-1.40.11.70.2-2.10.2-1.4
Bone: cortical apparent density2.22.97.1-1.4-2.10.8-1.8-1.52.02.72.4-1.02.30.4-1.9-0.1-2.10.8
Bone: cortical area0.50.72.5-1.60.51.61.0-0.9-1.1-0.4-0.3-0.6-0.50.2-0.40.80.4-0.4
Bone: cortical porosity0.40.41.2-0.8-0.50.8-0.1-1.10.2-0.10.4-1.00.40.4-1.00.1-0.4-1.0
Bone: cortical porosity0.60.72.0-0.8-0.71.0-0.4-1.30.3-0.10.4-1.40.31.0-0.8-0.5-0.2-1.4
Bone: cortical thickness1.82.96.9-2.6-1.62.3-1.0-2.40.91.71.9-1.81.71.0-2.10.2-1.5-0.8
Bone: cortical thickness1.21.34.3-2.1-0.71.70.0-1.60.21.01.2-0.91.00.0-1.71.2-1.10.2
Bone: cortical tissue density2.02.76.6-1.3-2.00.7-1.7-1.41.92.62.3-0.92.20.3-1.8-0.0-2.10.8
Condit. Reinf. active minus inactive responses1.41.67.02.40.3-2.6-0.22.00.7-0.0-0.31.80.0-1.31.0-0.1-0.20.7
Condit. Reinf. active-inactive response ratio0.40.42.1-0.20.5-0.10.60.4-0.40.3-0.00.70.0-0.8-0.01.2-0.11.5
Condit. Reinf. active responses2.22.710.83.30.7-3.2-0.22.60.5-0.7-0.92.0-0.6-1.01.8-0.90.5-0.1
Condit. Reinf. inactive responses1.72.07.92.80.4-2.5-0.51.90.4-1.0-1.01.1-0.8-0.11.7-1.60.8-1.4
Incentive salience index mean1.61.96.22.51.1-2.30.81.9-0.3-1.5-1.31.6-1.0-1.21.3-0.10.8-0.2
Condit. Reinf. lever presses1.62.28.21.71.5-1.11.51.0-1.2-2.9-2.00.6-1.8-0.61.0-0.21.5-1.5
Condit. Reinf. active minus inactive responses0.70.82.1-0.21.30.20.90.9-1.4-0.3-1.00.8-1.2-0.11.40.21.20.3
Condit. Reinf. active-inactive response ratio0.50.61.9-1.30.51.40.3-0.2-1.10.1-0.4-0.4-0.70.80.7-0.20.9-0.4
Condit. Reinf. active responses1.21.73.71.01.7-1.11.41.7-1.2-0.7-1.21.9-1.1-1.51.31.10.91.2
Condit. Reinf. inactive responses1.51.94.62.01.1-2.11.21.7-0.2-0.9-0.82.0-0.5-2.10.41.30.01.4
Condit. Reinf. lever presses1.31.75.0-0.81.81.21.90.3-2.2-1.3-1.50.4-1.7-0.30.91.01.6-0.6
Condit. Reinf. lever reinforcers received1.01.43.30.71.5-1.01.41.5-1.1-0.6-1.01.8-0.9-1.41.01.20.71.0
Conditioned reinforcement - actives0.10.10.4-0.1-0.10.30.1-0.5-0.1-0.5-0.1-0.5-0.2-0.1-0.2-0.60.2-0.6
Conditioned reinforcement - inactives0.20.31.00.4-0.3-0.6-0.30.10.60.50.40.40.5-0.7-0.2-0.2-0.61.0
Conditioned locomotion0.81.03.0-1.0-0.70.5-0.0-1.10.71.01.0-0.51.1-0.3-1.71.4-1.31.3
Patch foraging indifference point 0 sec0.10.20.5-0.30.50.30.30.2-0.7-0.3-0.40.1-0.50.20.6-0.10.6-0.2
Patch foraging indifference point AUC0.70.82.31.2-0.9-1.4-0.80.21.50.30.80.31.0-0.8-0.8-0.2-1.20.6
Delay disc. indifference point, 0s delay1.11.24.72.10.1-2.2-0.51.60.60.3-0.31.2-0.1-0.51.1-0.90.11.5
Delay disc. indifference point, 16s delay0.10.10.8-0.40.20.30.4-0.1-0.30.1-0.00.20.00.1-0.20.9-0.10.3
Delay disc. indifference point, 2s delay0.60.72.31.10.7-1.40.61.3-0.2-0.1-0.41.5-0.2-1.10.50.90.0-0.4
Delay disc. indifference point, 24s delay0.10.11.30.30.1-0.40.10.30.0-0.1-0.10.40.00.10.10.4-0.1-1.1
Delay disc. indifference point, 4s delay1.21.32.51.31.2-1.20.81.6-0.9-1.0-1.21.4-1.1-0.51.40.21.0-1.1
Delay disc. indifference point, 8s delay3.23.35.72.02.2-2.02.02.3-1.4-1.9-1.92.4-1.6-1.81.51.51.2-1.2
Indifference point function ln k0.71.02.9-1.01.11.20.90.2-1.7-0.6-1.0-0.1-1.30.71.2-0.01.5-0.1
Indifference point function log k0.71.02.9-1.01.11.20.90.2-1.7-0.6-1.0-0.1-1.30.71.2-0.01.5-0.1
Patch foraging total patch changes 0 sec0.00.10.3-0.40.40.20.30.1-0.5-0.1-0.20.2-0.3-0.10.30.30.3-0.1
Patch foraging total patch changes 12 sec0.40.61.60.3-1.0-0.4-0.8-0.51.30.50.9-0.31.0-0.1-0.9-0.3-1.10.5
Patch foraging total patch changes 18 sec0.20.30.8-0.8-0.40.7-0.0-0.80.20.10.5-0.40.5-0.1-0.90.3-0.6-0.4
Patch foraging total patch changes 24 sec0.70.82.61.4-0.5-1.6-1.11.01.21.00.60.90.7-0.40.5-0.8-0.60.7
Patch foraging total patch changes 6 sec0.40.51.71.0-0.6-1.1-1.20.50.90.60.40.10.40.30.5-1.3-0.20.1
Patch foraging time to switch 0 sec0.50.82.1-0.8-0.91.3-0.8-1.10.40.20.4-1.40.31.3-0.4-1.1-0.1-0.7
Patch foraging water rate 0 sec0.91.43.40.41.5-1.01.41.5-1.1-0.1-0.81.8-0.7-1.50.81.80.51.3
Patch foraging water rate 12 sec1.01.63.60.81.6-0.91.11.8-1.4-0.3-1.31.6-1.4-0.71.90.51.30.9
Patch foraging water rate 18 sec0.71.04.50.2-0.4-1.1-0.60.60.81.80.91.01.0-0.6-0.00.7-1.02.1
Patch foraging water rate 24 sec0.20.32.0-0.0-0.2-0.4-0.50.40.21.00.30.20.20.40.5-0.4-0.01.4
Patch foraging water rate 6 sec1.21.73.41.01.7-1.01.11.8-1.4-0.7-1.51.5-1.4-0.71.80.31.41.1
Seeking ratio, delayed vs. immediate footshock4.04.68.32.12.6-1.42.02.4-2.3-2.6-2.91.7-2.8-0.92.70.12.6-0.6
Distance traveled before self-admin1.41.53.30.31.40.21.10.7-1.7-1.7-1.60.2-1.70.41.5-0.31.8-1.3
Distance traveled after self-admin2.62.95.10.82.2-0.42.21.4-2.1-2.3-2.01.5-2.0-1.51.41.11.7-1.7
Extensor digitorum longus weight1.14.39.73.12.1-3.01.43.1-0.9-1.4-1.92.9-1.6-2.12.20.51.31.3
Bone: elastic displacement0.40.51.20.1-0.7-0.6-0.6-0.11.00.90.90.31.0-0.5-0.70.4-1.10.3
Bone: elastic work0.20.20.5-0.5-0.50.2-0.3-0.40.50.60.7-0.10.7-0.1-0.60.3-0.7-0.6
Bone: endosteal estimation3.16.812.51.63.5-1.03.22.4-3.3-3.5-3.51.9-3.4-1.22.70.93.1-0.2
Bone: endosteal perimeter1.83.87.41.32.6-0.92.51.8-2.4-2.7-2.61.6-2.5-1.11.80.92.20.1
Epididymis fat weight2.55.915.10.3-3.2-1.2-2.9-1.23.93.13.2-0.73.4-0.1-2.6-0.7-3.50.9
Delta time in closed arm before/after self-admin1.01.02.4-1.0-0.90.4-0.3-1.00.91.11.3-0.41.3-0.2-1.61.3-1.4-0.0
Delta time in open arm before/after self-admin2.72.69.6-1.5-1.22.2-1.7-1.50.10.70.5-2.30.02.90.3-3.10.61.0
Diff in mean of infusions in LGA sessions2.42.66.70.32.10.32.40.7-2.3-2.6-2.10.7-2.1-1.01.01.11.8-0.3
Delay discount exponential model param1.81.93.7-1.5-1.61.6-1.5-1.81.01.31.4-1.91.11.3-1.1-1.3-0.81.4
Extinction: sum of active levers before priming0.60.61.8-0.90.11.30.2-0.7-0.7-0.5-0.4-1.1-0.61.20.1-0.50.80.6
Active lever presses in extinction session 60.60.61.30.40.9-0.10.60.6-1.0-1.0-1.00.3-1.1-0.11.1-0.51.10.3
Bone: final force0.20.30.70.00.7-0.10.80.3-0.7-0.6-0.50.5-0.5-0.50.20.70.3-0.4
Bone: final moment0.10.20.8-0.40.40.20.7-0.1-0.4-0.3-0.10.3-0.1-0.5-0.30.9-0.1-0.5
Food consumed during 24 hour testing period3.54.211.6-0.22.90.33.41.2-2.9-2.3-2.21.8-2.2-1.80.92.81.7-0.0
Glucose0.30.40.8-0.8-0.60.9-0.7-0.70.30.80.5-0.80.40.9-0.3-0.5-0.2-0.1
Heart weight0.50.72.00.70.0-1.2-0.00.80.50.80.41.30.6-1.4-0.10.8-0.81.0
Delay discount hyperbolic model param1.61.63.2-1.3-1.51.4-1.4-1.71.01.21.3-1.81.01.2-1.1-1.2-0.81.1
Intermittent access intake day 1-15 change0.60.64.61.00.3-0.90.50.50.1-0.4-0.11.1-0.0-2.2-0.1-0.1-0.30.7
Intermittent access intake escalation1.11.15.71.21.0-1.01.20.9-0.6-1.2-0.81.4-0.7-2.40.40.30.30.1
Intermittent access intake escalation 21.71.74.31.51.4-1.11.41.3-1.0-1.7-1.41.5-1.3-2.11.00.11.0-0.9
Intermitt. access day 1 inactive lever presses0.30.33.1-0.1-0.3-0.0-0.3-0.10.30.30.3-0.20.30.6-0.20.3-0.21.8
Intermitt. access day 15 inactive lever presses2.12.318.80.5-1.1-1.0-0.8-0.11.61.01.20.31.5-0.6-1.30.8-1.74.3
Intermitt. access escalation Index2.92.58.4-0.21.7-0.12.40.6-1.5-0.9-0.91.8-0.8-2.8-0.32.90.1-2.3
Intermittent access day 1 total infusions1.92.24.7-1.9-1.61.8-1.0-2.21.01.01.5-2.01.31.7-1.90.2-1.20.6
Intermittent access day 15 total infusions0.30.31.4-0.5-0.40.70.2-1.00.2-0.30.4-0.50.4-0.5-1.20.4-0.60.6
Intermittent access terminal intake (last 3 days)0.30.31.0-0.30.20.40.8-0.5-0.2-0.6-0.1-0.00.0-1.0-0.90.9-0.30.9
Intermittent access total infusions0.91.03.4-1.7-0.61.80.0-1.8-0.0-0.20.5-1.50.40.9-1.40.4-0.40.5
Intermittent access day 1 locomotion2.32.44.7-1.5-1.81.1-1.2-1.91.51.51.8-1.71.81.4-2.20.6-1.70.8
Intermittent access day 15 total locomotion0.90.93.3-0.9-0.90.7-0.5-1.10.70.80.9-1.00.90.9-1.20.5-0.81.8
Intermittent access total locomotion0.40.51.3-1.0-0.30.9-0.1-0.9-0.00.30.3-1.00.31.1-0.70.6-0.11.1
Intermittent access standard deviation0.40.53.00.80.3-0.70.60.2-0.0-1.0-0.40.2-0.2-1.0-0.30.30.01.7
Left kidney weight0.41.04.40.90.8-1.31.01.0-0.2-0.4-0.31.6-0.1-2.1-0.11.5-0.3-0.4
Right kidney weight0.30.92.51.40.8-1.50.91.2-0.2-0.8-0.71.4-0.4-1.60.40.90.10.4
Cocaine induced anxiety0.20.31.20.4-0.2-0.1-0.4-0.10.1-0.4-0.3-0.6-0.31.00.3-1.10.5-0.8
Post-drug Anxiety1.11.25.20.4-1.3-0.1-1.7-0.51.20.60.6-1.20.51.80.1-2.3-0.20.7
Baseline Anxiety1.51.63.8-0.3-1.5-0.1-1.6-0.51.71.81.6-0.41.60.5-0.8-0.7-1.42.0
Tail length0.51.67.12.50.2-2.7-0.41.90.8-0.0-0.31.60.0-1.11.0-0.4-0.11.0
Length with tail0.51.96.32.11.0-2.50.91.90.0-0.4-0.72.2-0.3-2.20.61.1-0.11.0
Length without tail0.92.08.2-0.31.8-0.12.60.4-1.6-1.3-1.11.2-0.9-2.1-0.42.90.40.2
Times rat made contact with spout1.21.43.9-0.21.70.22.00.7-1.7-1.3-1.31.0-1.2-1.00.51.81.00.3
Lifetime Intake1.31.54.2-1.7-1.21.8-0.5-2.00.60.31.0-1.80.91.1-1.70.1-0.80.7
Liver weight, left0.20.31.2-0.10.6-0.20.90.3-0.5-0.4-0.30.7-0.2-0.9-0.01.10.0-0.9
Liver weight, right0.61.03.21.30.3-1.80.31.20.50.20.11.60.4-1.80.01.0-0.70.8
Locomotor activity0.10.20.6-0.00.4-0.00.70.1-0.3-0.1-0.20.5-0.2-0.8-0.20.8-0.0-0.5
Locomotor testing distance0.10.10.3-0.50.30.40.4-0.0-0.30.3-0.00.2-0.1-0.3-0.00.60.00.2
Locomotor testing rearing0.10.10.6-0.30.00.1-0.00.1-0.00.70.20.20.1-0.10.10.2-0.10.7
Locomotion in novel chamber0.30.40.8-0.9-0.50.7-0.3-0.80.30.50.5-0.70.50.8-0.70.4-0.4-0.9
Locomotion in novel chamber post-restriction0.20.30.6-0.1-0.5-0.1-0.4-0.20.60.50.70.10.7-0.6-0.5-0.2-0.70.8
Fecal boli incidents, locomotor time 11.61.83.61.71.3-1.91.51.4-0.5-1.5-1.11.6-0.8-1.90.31.40.3-1.3
Change in fecal boli incidents, locomotor task1.71.66.4-1.90.32.50.1-1.0-1.5-0.3-0.6-1.4-1.01.80.7-1.11.4-0.8
Time >=10cm from walls, locomotor time 10.60.61.80.50.9-0.20.90.4-0.9-1.4-1.10.2-1.1-0.20.60.11.00.5
Bouts of movement, locomotor time 10.30.31.11.00.3-1.10.30.80.1-0.4-0.30.9-0.1-0.80.20.6-0.10.1
Total resting periods, locomotor time 10.20.20.50.60.4-0.60.40.5-0.1-0.4-0.30.7-0.1-0.70.10.7-0.0-0.0
Rest time, locomotor task time 10.70.74.0-0.70.80.41.20.2-0.80.4-0.20.8-0.2-1.0-0.22.0-0.01.2
Distance moved, locomotor task time 10.60.61.90.7-0.9-0.8-1.30.11.20.60.7-0.20.70.40.1-1.4-0.50.6
Vertical activity count, locomotor time 10.20.20.90.5-0.6-0.5-0.80.00.70.10.3-0.30.30.50.1-1.0-0.2-0.1
Time >=10cm from walls, locomotor time 20.40.41.7-0.7-0.10.50.5-0.60.00.40.4-0.10.4-0.7-1.01.1-0.61.3
Bouts of movement, locomotor time 21.01.12.61.2-0.9-1.6-0.90.41.60.90.90.61.2-0.8-0.60.1-1.31.4
Total resting periods, locomotor time 20.80.82.21.0-0.7-1.4-0.70.41.30.70.70.61.0-0.7-0.50.1-1.11.5
Rest time, locomotor task time 21.31.53.5-1.6-1.01.3-0.6-1.50.71.51.3-1.01.20.5-1.50.4-1.11.9
Distance moved, locomotor task time 20.60.72.41.60.1-1.5-0.61.20.40.2-0.30.8-0.2-0.11.1-1.00.30.6
Vertical activity count, locomotor time 20.20.20.50.70.3-0.70.20.6-0.1-0.3-0.30.6-0.3-0.60.30.10.2-0.2
Light reinforcement 11.83.39.42.31.6-2.81.72.3-0.5-1.3-1.12.9-0.7-3.10.71.80.1-0.8
Light reinforcement 21.21.69.0-1.70.01.90.8-1.6-0.7-0.9-0.0-1.3-0.20.5-1.20.60.1-3.0
Bone: marrow area3.16.612.51.43.5-0.83.22.3-3.4-3.5-3.51.9-3.4-1.22.61.03.1-0.2
Bone: maximum diameter3.76.814.00.83.7-0.33.72.0-3.7-3.3-3.42.0-3.3-1.62.21.82.90.5
Bone: maximum force0.50.81.80.31.2-0.31.30.7-1.1-1.2-1.00.8-1.0-0.80.50.90.8-0.6
Bone: maximum moment0.30.51.4-0.20.90.11.20.2-0.9-0.9-0.70.5-0.6-0.70.01.00.4-0.7
Mean time between licks in bursts0.20.30.9-0.5-0.50.6-0.1-0.90.4-0.10.4-0.70.4-0.0-1.0-0.0-0.5-0.3
Mean num. licks in bursts0.70.91.7-1.1-0.70.5-0.3-0.80.71.31.2-0.11.2-0.4-1.31.1-1.30.2
Cd content in liver0.90.93.61.80.2-1.9-0.21.40.50.1-0.31.3-0.1-0.90.8-0.2-0.01.3
Co content in liver1.21.43.21.0-0.5-1.7-0.20.51.40.91.01.21.3-1.8-1.01.1-1.61.1
Cu content in liver0.60.71.9-0.1-0.7-0.4-0.4-0.31.01.01.10.31.2-0.8-1.10.8-1.40.6
Fe content in liver1.72.06.20.10.50.6-0.40.2-1.1-1.0-1.3-1.0-1.62.21.9-2.52.0-2.0
K content in liver0.10.10.30.20.2-0.3-0.10.4-0.1-0.0-0.20.2-0.20.20.5-0.30.30.4
Mg content in liver0.70.71.70.91.0-1.00.81.2-0.6-0.4-0.71.3-0.6-0.90.90.60.51.0
Mn content in liver0.80.93.3-1.8-0.11.80.7-1.6-0.6-0.30.2-1.20.10.4-1.30.8-0.10.1
Na content in liver0.80.91.90.10.50.40.2-0.0-0.9-1.3-1.0-0.8-1.21.31.0-1.21.4-1.1
Rb content in liver1.01.23.51.41.1-1.30.31.8-0.7-0.5-1.11.3-1.0-0.41.9-0.51.10.6
Se content in liver0.81.02.6-1.2-1.11.3-0.9-1.50.60.50.8-1.60.71.4-0.9-0.8-0.4-0.5
Sr content in liver0.40.31.31.00.5-0.70.50.5-0.3-1.1-0.70.3-0.6-0.40.4-0.10.5-0.2
Zn content in liver0.50.51.3-0.3-0.4-0.10.0-0.40.70.70.80.20.9-0.8-1.21.1-1.10.9
Bone: minimum diameter0.20.41.9-0.70.60.51.1-0.3-0.7-0.5-0.20.2-0.2-0.8-0.61.4-0.1-0.0
Time in familiar zone, hab. session 11.41.33.30.81.4-0.31.40.9-1.4-1.8-1.60.6-1.5-0.51.00.41.4-0.0
Time in novel zone, hab. session 11.31.34.7-1.0-1.10.4-0.9-0.61.12.21.60.01.6-0.3-1.20.6-1.60.7
Total zone transitions, hab. session 11.11.54.61.5-1.5-1.4-2.00.22.00.81.0-0.31.10.5-0.0-2.1-0.9-0.3
Total locomotion distance, hab. session 11.72.46.81.5-2.0-1.5-2.60.12.51.51.5-0.31.60.6-0.2-2.3-1.3-0.2
Locomotion velocity, hab. session 11.11.54.71.3-1.6-1.2-2.10.12.00.81.0-0.41.10.70.0-2.2-0.8-0.5
Time in familiar zone, hab. session 20.20.20.4-0.20.50.30.40.3-0.70.0-0.40.3-0.50.00.60.20.50.5
Time in novel zone, hab. session 20.10.10.4-0.7-0.10.60.1-0.6-0.10.00.2-0.40.20.2-0.50.3-0.2-0.4
Total zone transitions, hab. session 21.51.97.22.7-0.8-2.7-1.51.31.8-0.10.30.70.6-0.20.6-1.8-0.5-1.4
Total locomotion distance, hab. session 21.62.17.12.6-1.2-2.7-1.81.02.20.20.70.61.0-0.30.2-1.7-1.0-1.0
Locomotion velocity, hab. session 21.41.95.32.3-1.4-2.3-1.80.62.20.20.80.21.1-0.1-0.2-1.7-1.1-1.3
Novel to familiar place preference ratio0.30.31.00.40.7-0.50.80.5-0.5-0.6-0.50.8-0.4-1.00.20.80.20.3
Novelty place preference0.70.71.70.41.1-0.51.30.7-0.9-0.8-0.81.1-0.7-1.30.31.20.40.5
Time in novel zone, NPP test1.11.12.70.11.5-0.31.60.9-1.3-0.9-1.01.2-0.9-1.40.51.50.70.6
Total zone transitions, NPP test0.71.04.12.0-0.3-1.8-0.91.20.9-0.2-0.10.70.0-0.11.0-1.40.1-0.2
Total locomotion distance, NPP test1.01.46.22.5-0.5-2.3-1.21.31.3-0.1-0.00.70.2-0.20.9-1.6-0.2-0.6
Locomotion velocity, NPP test1.21.76.02.5-1.0-2.1-1.70.91.7-0.00.20.20.40.40.7-2.3-0.3-1.0
Intraocular pressure0.20.30.90.20.1-0.60.00.60.20.80.30.90.4-0.90.10.5-0.40.5
Delta distance traveled before/after self-admin0.80.94.70.30.9-0.61.20.7-0.5-0.3-0.31.5-0.1-2.2-0.21.7-0.3-0.5
Delta ambulatory time before/after self-admin0.70.83.3-0.30.90.11.30.2-0.7-0.3-0.21.0-0.2-1.8-0.41.8-0.2-0.8
Parametrial fat weight0.10.20.50.7-0.4-0.7-0.70.30.70.40.30.20.4-0.20.1-0.7-0.3-0.3
Pavlov. Cond. lever latency1.72.16.8-2.2-1.31.5-1.1-1.40.92.61.9-0.71.70.6-1.30.6-1.50.4
Pavlov. Cond. magazine entry latency0.30.31.51.2-0.1-1.00.20.00.5-1.2-0.3-0.10.0-0.4-0.5-0.1-0.2-0.3
Pavlov. Cond. change in total contacts0.50.52.41.50.2-1.40.30.60.3-1.1-0.50.5-0.2-0.7-0.10.1-0.00.1
Pavlov. Cond. index score0.60.83.51.90.4-1.40.40.70.1-1.8-0.90.3-0.6-0.40.3-0.60.5-0.4
Pavlov. Cond. latency score0.70.83.41.80.5-1.40.50.7-0.0-1.9-1.00.3-0.8-0.40.4-0.60.6-0.5
Pavlov. Cond. lever contacts1.01.23.91.81.0-1.30.91.0-0.6-2.0-1.40.7-1.1-0.70.8-0.20.9-0.2
Pavlov. Cond. magazine entry number0.20.31.3-1.10.30.90.2-0.0-0.70.80.10.2-0.10.00.30.50.20.2
Pavlov. Cond. intertrial magazine entries0.91.14.11.50.4-1.3-0.71.7-0.00.2-0.60.9-0.60.42.0-1.50.9-0.4
Pavlov. Cond. lever-magazine prob. diff.0.70.94.02.00.5-1.50.50.70.0-1.9-1.00.3-0.7-0.40.3-0.50.6-0.4
Pavlov. Cond. response bias0.40.52.61.60.2-1.30.20.60.3-1.3-0.60.4-0.3-0.50.1-0.30.1-0.1
Pavlov. Cond. lever latency1.82.44.5-0.7-2.10.3-1.9-1.52.11.82.0-1.32.00.7-1.7-0.5-1.90.3
Pavlov. Cond. magazine entry latency1.11.34.1-1.3-0.91.7-0.8-1.60.10.00.3-2.00.11.9-0.4-1.40.3-1.0
Pavlov. Cond. change in total contacts0.30.40.80.30.9-0.20.80.7-0.9-0.6-0.80.7-0.8-0.40.80.30.80.3
Pavlov. Cond. index score0.70.92.20.11.10.40.90.4-1.4-1.4-1.3-0.0-1.40.41.1-0.41.5-0.6
Pavlov. Cond. latency score1.01.32.9-0.21.30.71.10.3-1.7-1.5-1.5-0.1-1.70.51.2-0.31.7-0.8
Pavlov. Cond. lever contacts1.82.54.80.62.2-0.22.01.3-2.2-2.0-2.11.2-2.1-0.81.60.61.9-0.4
Pavlov. Cond. magazine entry number0.50.62.10.60.0-1.00.20.60.50.50.41.20.7-1.5-0.51.2-0.90.6
Pavlov. Cond. intertrial magazine entries0.20.30.80.80.4-0.80.50.60.1-0.4-0.20.8-0.0-0.9-0.10.9-0.20.0
Pavlov. Cond. lever-magazine prob. diff.0.60.71.80.00.90.40.80.2-1.2-1.3-1.2-0.1-1.30.40.9-0.31.3-0.5
Pavlov. Cond. response bias0.60.81.70.51.0-0.20.80.7-1.1-1.2-1.20.3-1.30.11.1-0.31.3-0.4
Time in closed arm before self-admin0.60.61.30.61.0-0.31.00.6-0.9-1.1-1.10.5-1.0-0.50.70.10.9-0.8
Time in closed arm after self-admin0.30.30.9-0.2-0.5-0.1-0.1-0.40.60.50.6-0.10.7-0.3-0.90.8-0.8-0.5
Time in open arm before self-admin1.01.13.50.11.3-0.21.60.7-1.2-1.2-1.00.9-0.9-1.00.31.90.7-1.0
Time in open arm after self-admin1.21.33.2-1.00.41.80.1-0.5-1.3-0.8-0.9-1.2-1.21.71.0-1.41.6-0.9
Bone: periosteal estimation1.93.97.90.52.8-0.22.81.5-2.8-2.6-2.61.4-2.6-1.11.71.22.3-0.1
Bone: periosteal perimeter1.01.73.90.11.70.31.60.8-2.0-1.7-1.80.6-1.8-0.11.40.21.8-0.2
Bone: post-yield work2.53.46.01.42.4-0.92.02.0-2.2-2.2-2.41.6-2.4-0.82.20.32.2-0.2
Progressive ratio test 1 active lever presses0.40.41.7-0.9-0.10.70.5-0.8-0.1-0.10.3-0.50.30.2-1.11.3-0.40.5
Progressive ratio test 1 breakpoint0.40.41.9-1.0-0.00.80.6-0.9-0.2-0.20.2-0.60.20.2-1.11.4-0.30.6
Progressive ratio test 1 inactive lever presses0.40.51.3-0.8-0.60.7-0.2-1.00.40.20.6-0.80.60.6-1.00.3-0.61.1
Progressive ratio test 2 active lever presses0.20.31.2-0.4-0.30.30.1-0.70.3-0.20.3-0.40.4-0.1-0.90.5-0.51.1
Progressive ratio test 2 breakpoint0.20.21.5-0.3-0.20.30.1-0.60.1-0.30.2-0.40.2-0.1-0.70.3-0.31.2
Progressive ratio test 2 inactive lever presses1.61.85.0-1.5-1.31.5-0.7-1.90.80.41.1-1.81.01.4-1.60.0-0.92.2
Incentive Sensitization - Responses0.20.21.00.0-0.4-0.2-0.2-0.40.5-0.10.4-0.30.4-0.2-0.70.0-0.51.0
Incentive Sensitization - Breakpoint0.30.31.20.2-0.7-0.4-0.4-0.40.80.10.6-0.20.7-0.3-0.8-0.1-0.81.1
Sum of active levers in priming session hrs 5-60.30.31.0-0.50.60.60.60.1-0.9-0.2-0.50.1-0.6-0.10.50.20.71.0
Progressive ratio1.21.44.01.41.0-1.71.31.2-0.3-1.0-0.61.6-0.3-2.00.01.7-0.11.1
Food seeking constrained by brief footshock3.34.07.11.42.7-1.42.22.5-2.2-1.6-2.22.5-2.2-1.82.31.21.9-1.1
Seeking ratio, punishment vs. effort0.60.72.20.00.70.20.10.7-0.9-0.1-0.80.2-1.00.61.5-0.91.2-1.4
Retroperitoneal fat weight1.03.38.21.4-1.7-2.3-1.60.32.92.02.00.92.4-1.4-1.60.3-2.71.4
Reaction time number correct0.40.61.80.70.4-0.1-0.10.6-0.5-0.6-0.80.0-0.90.51.3-1.31.1-1.1
Reaction time mean minus median1.11.42.6-1.2-1.41.0-1.0-1.51.21.51.6-0.91.50.0-1.6-0.2-1.50.4
Reaction time mean minus median AUC0.81.12.0-1.3-1.21.4-0.8-1.40.81.21.2-1.11.10.2-1.3-0.5-1.00.3
Reaction time num false alarms0.70.92.0-0.6-1.30.5-1.4-0.91.01.21.0-1.10.91.2-0.5-1.1-0.60.4
Reaction time num false alarms AUC0.81.12.5-0.6-1.40.6-1.6-0.91.01.41.0-1.30.91.5-0.4-1.4-0.50.4
Reaction time trials correct on left0.40.61.80.70.4-0.1-0.10.6-0.5-0.6-0.80.0-0.90.51.3-1.31.1-1.1
Reaction time trials on left0.40.62.20.60.30.0-0.30.5-0.5-0.5-0.7-0.1-0.90.61.3-1.51.1-1.1
Reaction time mean1.01.43.2-1.6-1.21.7-0.7-1.80.71.11.3-1.31.10.4-1.6-0.1-1.10.1
Reaction time mean AUC0.70.92.2-1.3-1.01.5-0.6-1.50.50.81.0-1.10.90.3-1.3-0.2-0.80.0
Median of all reaction times0.91.33.0-1.6-1.21.7-0.6-1.70.71.01.1-1.31.00.6-1.5-0.2-1.00.1
Reaction time omissions1.31.74.3-0.3-1.80.5-2.1-1.01.61.51.3-1.41.21.6-0.5-1.9-0.80.1
Reaction time false alarm rate1.01.42.9-0.9-1.50.5-1.4-1.11.31.71.5-1.11.41.0-1.1-0.4-1.20.8
Reaction time premature initiation rate0.30.41.40.60.2-0.80.20.70.30.50.21.10.3-1.20.00.6-0.50.4
Reaction time premature initiations0.20.31.10.90.4-0.80.11.00.00.3-0.21.0-0.2-0.90.7-0.10.1-0.0
Std. dev. reaction times1.41.93.1-1.5-1.71.4-1.3-1.81.31.71.7-1.31.50.5-1.6-0.7-1.40.4
Reaction time trials completed0.40.62.20.60.30.0-0.30.5-0.5-0.5-0.7-0.1-0.90.61.3-1.51.1-1.1
Reaction time trials AUC0.50.72.10.60.40.0-0.10.6-0.6-0.6-0.9-0.0-1.00.61.4-1.41.2-1.2
Run reversals in cocaine runway, females1.11.12.0-1.4-1.01.0-0.6-1.20.71.21.2-0.81.20.5-1.30.6-1.11.3
Run reversals in cocaine runway, males1.21.22.91.71.0-1.50.41.7-0.5-0.8-1.21.2-1.1-0.41.6-0.61.10.1
Latency to leave start box in cocaine runway0.40.51.40.00.30.40.2-0.1-0.6-1.0-0.7-0.5-0.80.80.6-0.80.9-1.2
Latency to leave start box in cocaine runway, F0.20.20.70.60.4-0.60.30.5-0.3-0.7-0.60.3-0.5-0.10.5-0.10.5-0.8
Latency to leave start box in cocaine runway, M0.50.51.9-0.3-0.60.6-0.8-0.70.2-0.10.1-1.20.01.40.0-1.30.20.7
Std. dev. time between licks in bursts0.81.02.61.50.8-0.90.50.9-0.6-1.6-1.30.4-1.2-0.21.1-1.01.2-0.4
Total sessions with >9 infusions0.40.51.6-0.90.21.30.6-0.9-0.6-1.0-0.3-0.9-0.40.7-0.50.70.3-0.2
Short access day 1 total inactive lever presses0.30.31.1-0.5-0.20.20.2-0.30.30.30.50.20.6-0.6-0.81.1-0.80.6
Short access day 10 total inactive lever presses0.10.10.60.0-0.20.0-0.30.00.10.20.1-0.10.00.10.2-0.80.00.4
Short access day 1 total infusions0.60.63.2-0.7-0.60.8-0.2-1.20.3-0.20.4-1.10.40.5-1.10.1-0.41.8
Short access day 10 total infusions1.82.06.9-2.2-0.82.6-0.2-2.3-0.2-0.30.4-2.40.22.2-1.2-0.20.1-0.3
Short access total infusions2.52.86.9-2.1-1.82.2-1.1-2.61.10.81.6-2.41.41.5-2.2-0.3-1.30.7
Short access day 1 locomotion0.30.30.60.50.6-0.30.80.4-0.4-0.8-0.60.5-0.5-0.70.10.70.30.8
Short access day 10 total locomotion0.20.20.9-0.10.30.30.3-0.0-0.5-0.4-0.5-0.4-0.50.90.30.40.61.0
Short access total locomotion0.70.71.6-1.1-0.51.10.0-1.30.10.10.4-1.30.41.2-1.10.9-0.31.0
One hour access (0.3 mA shock)0.40.51.3-0.9-0.80.8-0.4-1.20.50.20.7-1.10.60.6-1.0-0.1-0.60.0
Compulsive drug intake1.21.24.9-2.20.12.20.5-1.3-1.0-0.00.1-1.1-0.21.0-0.60.60.3-1.7
One hour access (shock baseline)0.10.10.50.3-0.3-0.0-0.2-0.40.3-0.7-0.0-0.60.00.3-0.4-0.3-0.00.6
Social response proportion1.31.44.2-2.1-0.91.6-0.4-1.70.41.11.2-1.11.00.6-1.60.5-1.0-1.1
Social responses0.10.21.0-0.2-0.1-0.00.2-0.40.1-0.00.2-0.20.2-0.2-0.70.5-0.4-1.0
Social time0.10.10.4-0.7-0.10.5-0.0-0.4-0.20.20.1-0.4-0.10.4-0.1-0.30.1-0.5
Soleus weight6.017.629.64.55.2-3.94.25.4-3.8-4.3-4.94.9-4.5-3.24.71.64.01.4
Bone: stiffness0.10.20.70.50.4-0.40.00.7-0.3-0.1-0.40.5-0.4-0.00.8-0.30.5-0.1
Tibialis anterior weight3.010.317.92.44.2-1.93.53.7-3.7-3.4-4.13.1-3.9-1.73.91.13.70.9
Time to tail flick, vehicle, before self-admin0.60.61.60.60.7-0.20.30.7-0.8-0.7-0.90.3-1.0-0.01.3-1.01.1-0.7
Time to tail flick, vehicle, after self-admin2.32.56.1-0.31.90.91.70.5-2.5-2.1-2.1-0.1-2.30.91.60.52.4-0.9
Time to tail flick, test, before self-admin0.40.31.51.10.2-1.20.10.80.3-0.3-0.10.90.1-0.80.10.5-0.2-0.4
Time to tail flick, test, after self-admin1.11.11.61.11.2-1.11.11.3-0.9-1.2-1.11.3-1.0-1.10.90.80.8-0.6
Delta time to tail flick, vehicle, before/after SA0.50.51.2-0.00.90.20.90.4-1.1-0.9-1.00.0-1.00.50.70.61.0-0.6
Delta time to tail flick, test, before/after SA1.00.92.5-0.61.20.81.30.1-1.6-1.1-1.10.0-1.30.00.70.51.3-0.9
Tibia length0.82.410.9-1.01.70.62.9-0.2-1.8-1.7-1.00.8-0.8-1.8-1.03.30.3-0.0
Ambulatory time before self-admin0.60.61.90.30.60.20.40.2-0.8-1.4-1.0-0.4-1.00.80.8-0.61.2-0.8
Ambulatory time after self-admin1.92.14.20.11.90.32.00.8-2.1-1.9-1.70.9-1.8-1.01.11.11.5-1.6
Bone: tissue strength0.50.51.0-1.0-0.70.8-0.6-0.80.40.90.8-0.70.70.5-0.6-0.1-0.5-0.9
Total heroin consumption1.61.93.21.01.8-0.91.61.6-1.5-1.5-1.61.5-1.6-1.41.50.81.4-0.5
Bone: trabecular number0.40.62.00.5-0.0-0.0-0.3-0.0-0.2-0.9-0.6-0.7-0.71.00.7-1.40.9-1.3
Bone: trabecular spacing1.72.24.8-0.3-1.9-0.2-1.7-0.92.22.02.1-0.42.2-0.1-1.7-0.0-2.20.5
Bone: trabecular thickness0.30.31.3-1.10.30.70.7-0.5-0.50.20.20.00.1-0.5-0.71.1-0.3-0.2
Bone: trabecular tissue density0.70.92.5-1.1-0.30.50.2-0.60.31.21.00.21.0-0.9-1.21.6-1.21.5
Water consumed over 24 hours1.62.04.80.32.0-0.22.21.1-1.9-1.6-1.61.3-1.5-1.20.91.71.20.3
Number of responses in last shaping day2.32.46.7-0.12.00.42.60.3-2.1-2.3-1.80.5-1.7-1.20.22.21.40.2