Hub : Genes

Rgs9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA NM_019224.2 0.06 0.04 2.0e-05 0.03 0.04 0.04 0.04 3.9e-04 2.7e-05 6.2e-05 2.2e-05
2 Liver alternative polyA XM_039085765.1 0.06 0.03 3.3e-05 0.02 0.04 0.03 0.04 1.5e-03 5.1e-05 2.9e-04 7.9e-05
3 NAcc mRNA stability Rgs9 0.03 0.02 3.5e-03 0.02 0.02 0.01 0.01 5.6e-03 1.3e-03 1.1e-02 6.3e-03
4 Liver gene expression Rgs9 0.15 0.06 1.1e-16 0.12 0.12 0.12 0.12 2.2e-13 3.0e-13 1.1e-12 5.6e-13
5 PL gene expression Rgs9 0.06 0.05 2.9e-04 0.04 0.04 0.01 0.04 3.5e-05 5.7e-05 1.9e-02 9.3e-05
6 Brain gene expression Rgs9 0.05 0.03 7.0e-05 0.02 0.05 0.03 0.03 1.1e-02 3.8e-05 1.1e-03 9.0e-04
7 Liver alternative TSS XM_039085765.1 0.04 0.03 1.1e-03 0.01 0.01 0.01 0.01 4.8e-02 8.0e-03 1.9e-02 1.9e-02
8 Liver alternative TSS NM_019224.2 0.05 0.04 5.0e-04 0.03 0.02 0.01 0.02 3.5e-04 3.0e-03 1.2e-02 2.2e-03
9 Brain mRNA stability Rgs9 0.08 0.05 1.1e-05 0.06 0.05 0.05 0.05 4.1e-06 2.2e-05 3.8e-05 1.4e-05
10 NAcc gene expression Rgs9 0.05 0.03 4.5e-06 0.03 0.05 0.04 0.04 8.7e-05 2.7e-06 1.7e-05 1.1e-05
11 IL gene expression Rgs9 0.2 0.12 7.6e-03 0.03 0.02 0.02 0.01 6.7e-02 9.8e-02 1.1e-01 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.72.88.3-1.01.22.7-0.2-0.31.1-1.2-0.5-2.92.4-2.0
Area under the delay curve0.30.30.7-0.60.60.40.70.8-0.40.70.10.4-0.20.1
BMI with tail3.511.424.90.5-0.3-3.92.22.0-4.22.90.94.9-5.05.0
BMI without tail3.36.714.4-0.81.1-2.22.12.0-3.72.50.23.5-3.53.8
Body weight4.719.838.2-0.81.2-3.44.34.1-5.84.92.15.8-6.26.0
Weight adjusted by age2.02.35.81.1-0.8-1.91.21.1-1.41.40.42.2-2.41.5
Bone surface2.74.714.7-2.72.93.81.41.30.20.10.6-2.82.2-2.1
Bone volume2.64.413.1-2.93.13.61.71.6-0.20.50.8-2.31.7-1.8
Breakpoint value in progressive ratio session0.70.82.50.9-1.0-1.6-0.4-0.5-0.4-0.2-1.11.0-1.01.0
Number of licking bursts0.50.51.1-0.50.50.10.91.0-0.80.91.10.5-0.60.6
Context. condit. distance diff. score0.10.10.3-0.50.2-0.00.50.4-0.30.60.20.3-0.50.3
Locomotion velocity, session 10.00.00.2-0.10.1-0.2-0.10.0-0.2-0.1-0.40.40.00.1
Locomotion distance, session 10.10.10.7-0.20.3-0.3-0.4-0.1-0.3-0.2-0.80.4-0.00.1
Locomotion velocity, session 20.50.62.5-0.10.0-0.0-1.0-0.90.5-1.1-1.6-0.40.9-0.6
Locomotion distance, session 20.60.83.70.3-0.2-0.4-1.2-1.10.3-1.3-1.9-0.10.7-0.3
Locomotion velocity, session 31.51.75.21.4-1.1-1.9-1.2-1.3-0.2-0.9-2.31.1-0.61.0
Locomotion distance, session 30.10.10.6-0.40.40.40.10.0-0.0-0.1-0.7-0.20.2-0.2
Stereotopy head waving bouts, day 34.85.710.32.3-2.8-1.2-3.2-3.22.7-2.7-2.6-0.81.6-1.6
Stereotopy head waving duration, day 32.42.85.21.4-1.7-0.7-2.3-2.31.9-2.0-1.9-0.71.3-1.3
Locomotion velocity, session 70.10.10.30.1-0.10.2-0.4-0.60.4-0.5-0.2-0.40.4-0.4
Locomotion distance, session 70.71.02.8-1.71.51.20.90.9-0.60.61.1-0.60.2-0.2
Stereotopy head waving bouts, day 72.12.45.81.9-1.7-0.8-1.7-1.91.3-1.9-2.4-0.70.9-0.3
Stereotopy head waving duration, day 73.84.67.92.6-2.5-0.8-2.5-2.72.2-2.7-2.8-1.21.5-0.9
Locomotion velocity, session 80.00.00.2-0.30.20.10.10.10.10.2-0.10.30.0-0.4
Locomotion distance, session 80.10.20.8-0.60.5-0.1-0.3-0.2-0.3-0.2-0.90.30.1-0.1
Degree of sensitization distance0.50.51.9-1.10.90.60.40.5-0.20.41.4-0.20.1-0.3
Degree of sensitization stereotypy1.11.24.31.6-1.2-0.8-1.0-1.20.4-1.3-2.1-0.20.20.4
Conditioned locomotion0.20.20.4-0.40.50.6-0.1-0.20.2-0.20.0-0.40.6-0.7
Cocaine response after cond. corrected0.60.72.1-0.91.01.11.00.9-0.20.81.5-0.30.1-0.3
Cocaine response after cond. not corrected0.80.92.1-1.11.21.31.11.1-0.40.91.5-0.40.1-0.2
Cocaine response before conditioning0.10.10.5-0.20.10.0-0.2-0.20.0-0.3-0.7-0.10.2-0.1
Saline control response2.22.96.70.7-0.3-2.30.50.5-2.11.1-0.82.5-2.42.6
Bone: connectivity density3.25.012.8-0.20.42.4-1.5-1.62.2-2.4-1.7-3.63.2-2.7
Bone: cortical apparent density2.12.85.72.2-2.4-2.2-2.0-2.01.1-1.3-2.10.8-0.2-0.0
Bone: cortical area1.11.64.3-2.11.80.11.21.2-1.71.2-0.71.3-0.80.7
Bone: cortical porosity1.71.95.0-2.02.21.41.71.7-1.31.20.7-0.1-0.10.2
Bone: cortical porosity2.42.65.7-2.12.41.12.22.1-1.91.70.80.5-0.70.7
Bone: cortical thickness3.55.715.82.3-2.4-4.0-1.8-1.9-0.6-0.8-3.52.9-1.82.0
Bone: cortical thickness2.42.88.61.6-1.8-1.8-2.2-2.10.8-1.7-2.90.50.20.1
Bone: cortical tissue density2.12.75.72.2-2.4-2.1-2.0-2.01.1-1.3-2.00.8-0.2-0.0
Condit. Reinf. active minus inactive responses2.73.06.3-2.52.30.82.12.1-1.92.11.41.1-1.00.7
Condit. Reinf. active-inactive response ratio0.70.81.4-1.21.00.81.11.2-0.51.11.2-0.0-0.2-0.0
Condit. Reinf. active responses2.22.66.9-2.62.51.01.81.9-1.81.70.90.8-0.70.5
Condit. Reinf. inactive responses0.30.41.6-1.21.30.50.40.4-0.70.1-0.50.10.10.0
Incentive salience index mean1.11.32.9-1.71.50.41.31.4-1.41.20.50.7-0.80.8
Condit. Reinf. lever presses0.30.41.40.1-0.1-0.80.10.1-0.80.1-0.60.7-0.81.2
Condit. Reinf. active minus inactive responses3.03.711.0-3.33.32.42.02.0-1.31.30.6-0.60.5-0.5
Condit. Reinf. active-inactive response ratio3.03.17.5-2.72.72.41.91.9-1.01.21.5-0.90.5-0.6
Condit. Reinf. active responses3.44.714.9-3.93.82.62.22.2-1.71.50.8-0.50.4-0.4
Condit. Reinf. inactive responses0.50.62.6-1.61.40.40.20.2-0.70.2-1.10.30.1-0.1
Condit. Reinf. lever presses1.62.25.3-2.32.30.81.71.7-1.91.40.00.6-0.70.9
Condit. Reinf. lever reinforcers received3.24.514.2-3.83.62.42.22.2-1.71.61.0-0.30.2-0.3
Conditioned reinforcement - actives2.62.64.80.8-0.70.8-1.7-1.61.9-2.0-1.2-2.02.2-1.9
Conditioned reinforcement - inactives0.00.10.2-0.20.40.20.30.2-0.30.20.3-0.00.10.0
Conditioned locomotion1.31.64.0-1.92.01.71.41.5-0.81.00.7-0.40.3-0.2
Patch foraging indifference point 0 sec2.94.69.6-2.42.6-0.42.12.1-3.12.40.62.5-2.12.0
Patch foraging indifference point AUC0.70.81.7-1.30.80.01.01.0-0.71.20.81.1-0.7-0.1
Delay disc. indifference point, 0s delay0.10.10.30.10.10.50.50.50.10.30.3-0.30.10.0
Delay disc. indifference point, 16s delay0.70.71.4-0.30.4-0.31.01.1-0.91.20.41.2-1.00.8
Delay disc. indifference point, 2s delay0.30.30.6-0.70.70.80.60.7-0.00.5-0.20.00.2-0.6
Delay disc. indifference point, 24s delay0.80.81.8-1.31.30.61.01.0-1.00.90.30.3-0.30.7
Delay disc. indifference point, 4s delay0.10.10.1-0.20.10.30.30.40.20.3-0.40.20.1-0.3
Delay disc. indifference point, 8s delay0.30.30.80.8-0.9-0.9-0.5-0.40.3-0.1-0.40.7-0.30.3
Indifference point function ln k1.21.74.90.1-0.10.3-1.5-1.60.9-1.7-2.2-1.31.5-1.0
Indifference point function log k1.21.74.90.1-0.10.3-1.5-1.60.9-1.7-2.2-1.31.5-1.0
Patch foraging total patch changes 0 sec2.64.18.8-2.22.3-0.61.91.9-3.02.20.52.5-2.11.9
Patch foraging total patch changes 12 sec2.73.45.7-2.42.40.52.12.1-2.22.31.51.7-1.30.7
Patch foraging total patch changes 18 sec2.22.87.3-1.21.0-1.21.41.3-2.21.90.72.7-2.21.6
Patch foraging total patch changes 24 sec2.53.07.4-2.72.40.21.91.7-2.21.90.61.6-1.20.9
Patch foraging total patch changes 6 sec5.78.413.3-3.33.1-0.13.33.2-3.63.61.93.1-2.82.0
Patch foraging time to switch 0 sec0.10.20.60.4-0.40.00.60.5-0.00.50.80.1-0.40.5
Patch foraging water rate 0 sec0.71.12.2-1.31.4-0.20.91.0-1.51.00.11.3-0.80.6
Patch foraging water rate 12 sec0.50.72.10.3-0.3-1.50.0-0.0-0.90.4-0.61.3-1.31.1
Patch foraging water rate 18 sec0.50.72.30.4-0.5-0.3-1.1-1.10.4-1.2-1.5-0.60.6-0.3
Patch foraging water rate 24 sec0.60.81.70.4-0.30.1-1.2-1.20.8-1.3-1.3-0.81.0-0.8
Patch foraging water rate 6 sec0.40.62.40.5-0.7-0.8-0.9-0.90.4-0.7-1.50.30.1-0.2
Seeking ratio, delayed vs. immediate footshock1.61.93.1-0.10.5-0.81.51.5-1.61.80.81.7-1.81.6
Distance traveled before self-admin0.20.20.60.1-0.1-0.10.80.7-0.00.5-0.40.5-0.30.0
Distance traveled after self-admin0.20.20.7-0.20.1-0.10.70.9-0.30.70.30.7-0.5-0.1
Extensor digitorum longus weight1.24.69.32.8-2.1-2.90.50.4-1.31.21.92.5-2.93.0
Bone: elastic displacement1.21.43.21.6-1.0-1.1-1.5-1.50.4-1.4-1.8-0.00.40.1
Bone: elastic work0.40.61.41.1-0.3-1.0-0.4-0.4-0.7-0.5-1.10.5-0.51.2
Bone: endosteal estimation9.921.647.3-6.96.65.65.75.6-2.74.34.8-1.10.2-1.0
Bone: endosteal perimeter10.622.052.2-7.26.95.75.65.6-2.84.14.4-1.20.4-1.1
Epididymis fat weight5.212.226.41.4-0.9-3.62.62.5-3.63.53.04.5-5.15.0
Delta time in closed arm before/after self-admin1.41.43.7-0.50.41.8-0.3-0.41.3-0.80.3-1.91.7-1.5
Delta time in open arm before/after self-admin1.81.73.61.0-1.2-0.5-1.9-1.91.4-1.7-1.4-1.01.0-0.8
Diff in mean of infusions in LGA sessions0.80.92.00.9-0.6-1.30.60.4-0.90.50.01.4-1.31.4
Delay discount exponential model param0.50.61.21.0-1.0-0.7-1.0-1.10.5-1.0-0.5-0.40.2-0.0
Extinction: sum of active levers before priming0.30.30.7-0.50.4-0.00.90.6-0.70.70.40.4-0.60.8
Active lever presses in extinction session 60.10.10.3-0.00.1-0.20.50.4-0.50.2-0.30.4-0.40.2
Bone: final force0.60.93.0-1.71.51.11.21.1-0.70.8-0.2-0.00.1-0.3
Bone: final moment0.50.93.0-1.71.51.11.01.0-0.50.7-0.3-0.10.2-0.5
Food consumed during 24 hour testing period2.02.47.11.4-1.3-2.7-0.3-0.3-1.00.5-1.02.4-2.01.9
Glucose0.00.00.10.0-0.1-0.10.20.1-0.00.30.20.0-0.20.1
Heart weight2.83.97.3-2.22.50.72.72.4-2.62.11.31.2-1.51.5
Delay discount hyperbolic model param0.40.41.00.9-0.8-0.5-0.9-1.00.4-0.9-0.2-0.40.20.1
Intermittent access intake day 1-15 change1.51.58.4-0.20.90.71.41.5-0.71.32.90.3-0.40.3
Intermittent access intake escalation1.51.59.3-0.10.80.81.31.4-0.61.23.10.2-0.30.2
Intermittent access intake escalation 22.02.010.8-0.81.31.41.41.5-0.51.43.3-0.1-0.00.0
Intermitt. access day 1 inactive lever presses0.50.51.5-1.20.9-0.00.30.4-1.00.6-0.20.2-0.61.0
Intermitt. access day 15 inactive lever presses0.50.61.10.7-0.3-0.70.70.6-0.70.71.10.8-0.91.0
Intermitt. access escalation Index0.20.20.4-0.1-0.00.6-0.2-0.20.6-0.3-0.4-0.60.6-0.6
Intermittent access day 1 total infusions0.40.42.80.3-0.1-0.4-0.5-0.7-0.0-0.8-1.7-0.00.30.1
Intermittent access day 15 total infusions0.60.72.4-0.21.00.61.21.1-0.80.81.60.2-0.10.4
Intermittent access terminal intake (last 3 days)0.70.82.1-0.51.21.01.21.1-0.60.81.5-0.10.20.0
Intermittent access total infusions0.10.10.20.00.50.10.20.1-0.4-0.0-0.10.00.20.3
Intermittent access day 1 locomotion0.70.71.7-0.61.00.11.11.0-1.30.80.30.6-0.61.1
Intermittent access day 15 total locomotion1.11.22.8-1.41.71.31.41.2-0.90.91.2-0.30.10.2
Intermittent access total locomotion1.71.94.1-1.21.70.21.71.7-2.01.51.01.0-1.01.4
Intermittent access standard deviation1.11.25.1-0.61.20.71.31.4-0.91.12.30.5-0.30.2
Left kidney weight0.51.33.5-0.30.5-1.10.90.6-1.90.7-0.41.3-1.51.9
Right kidney weight0.82.25.1-1.01.2-0.11.81.8-2.21.40.51.0-1.62.2
Cocaine induced anxiety0.60.71.70.2-0.20.9-0.6-0.41.1-0.8-0.4-1.31.2-1.3
Post-drug Anxiety0.40.41.40.4-0.20.9-0.0-0.01.0-0.2-0.1-0.80.8-1.2
Baseline Anxiety0.50.51.11.0-0.9-1.0-0.3-0.30.0-0.0-1.00.8-0.70.5
Tail length0.92.84.8-1.51.70.32.22.0-2.02.11.31.0-1.61.7
Length with tail1.55.49.0-1.41.6-0.33.02.9-2.83.02.02.0-2.62.5
Length without tail0.30.71.30.7-0.6-0.70.80.8-0.60.81.10.8-1.20.9
Times rat made contact with spout0.50.61.5-0.10.2-0.60.60.7-1.00.60.40.9-0.91.2
Lifetime Intake0.10.10.5-0.10.4-0.1-0.1-0.2-0.4-0.3-0.70.10.20.3
Liver weight, left0.30.61.10.3-0.30.4-0.7-0.71.1-0.8-0.6-0.81.0-1.0
Liver weight, right0.61.02.71.2-1.6-1.2-1.2-1.31.0-0.9-0.90.30.0-0.1
Locomotor activity0.81.33.6-1.11.1-0.60.90.9-1.90.7-1.11.3-1.11.4
Locomotor testing distance1.01.64.0-1.31.4-0.51.01.0-2.00.8-1.41.4-1.11.4
Locomotor testing rearing1.52.35.5-0.60.7-1.51.11.0-2.21.2-0.52.3-1.92.1
Locomotion in novel chamber0.20.20.50.5-0.5-0.50.50.4-0.20.5-0.20.7-0.70.3
Locomotion in novel chamber post-restriction0.00.00.10.2-0.1-0.1-0.2-0.3-0.0-0.20.2-0.00.10.3
Fecal boli incidents, locomotor time 11.11.23.6-1.11.31.61.01.0-0.10.61.9-0.70.6-0.6
Change in fecal boli incidents, locomotor task0.10.10.80.1-0.2-0.30.20.20.10.3-0.10.9-0.2-0.5
Time >=10cm from walls, locomotor time 10.90.92.00.9-1.0-0.5-1.3-1.41.0-1.3-0.5-0.60.7-0.9
Bouts of movement, locomotor time 10.60.61.50.5-0.2-0.90.50.5-0.90.70.60.9-1.11.2
Total resting periods, locomotor time 10.30.41.10.5-0.1-0.40.50.4-0.60.60.90.5-0.71.0
Rest time, locomotor task time 10.10.10.80.6-0.50.0-0.1-0.20.4-0.00.9-0.20.10.1
Distance moved, locomotor task time 10.91.03.31.3-1.2-1.8-0.5-0.5-0.2-0.1-0.91.3-1.00.7
Vertical activity count, locomotor time 10.50.51.90.8-0.8-1.4-0.4-0.4-0.10.1-0.41.1-0.80.3
Time >=10cm from walls, locomotor time 21.92.05.82.3-1.9-2.4-0.4-0.6-0.4-0.1-0.51.7-1.41.4
Bouts of movement, locomotor time 21.92.05.00.9-0.8-2.20.20.3-1.40.90.12.2-2.21.9
Total resting periods, locomotor time 21.41.53.90.7-0.6-1.90.10.3-1.20.80.12.0-1.91.6
Rest time, locomotor task time 21.71.94.30.9-1.01.0-1.4-1.32.1-1.40.1-1.81.7-1.5
Distance moved, locomotor task time 22.52.99.22.3-2.1-3.0-0.7-0.7-0.6-0.1-1.01.9-1.91.8
Vertical activity count, locomotor time 21.31.53.80.8-0.6-2.00.30.2-1.30.7-0.21.8-1.81.6
Light reinforcement 10.71.33.90.6-0.7-1.8-0.8-0.9-0.6-0.5-2.01.3-0.81.2
Light reinforcement 20.10.21.30.3-0.2-0.5-0.3-0.2-0.3-0.1-0.30.2-0.31.1
Bone: marrow area9.620.845.4-6.76.55.55.65.5-2.64.24.8-1.10.3-1.0
Bone: maximum diameter3.25.816.7-4.13.83.32.62.6-1.11.81.3-0.90.7-1.2
Bone: maximum force1.32.36.1-2.52.41.61.91.8-1.31.40.30.1-0.1-0.1
Bone: maximum moment1.32.26.1-2.52.41.61.81.7-1.21.30.20.1-0.0-0.3
Mean time between licks in bursts1.11.63.2-0.40.5-0.21.51.4-1.51.51.80.8-1.51.5
Mean num. licks in bursts0.10.20.50.4-0.3-0.5-0.6-0.50.2-0.5-0.70.10.10.0
Cd content in liver1.41.62.61.4-1.10.6-1.2-1.31.6-1.50.7-1.61.4-1.0
Co content in liver0.20.20.60.7-0.20.40.40.4-0.00.20.8-0.5-0.10.4
Cu content in liver0.30.31.0-0.60.51.00.00.10.4-0.20.4-0.80.7-0.8
Fe content in liver0.20.30.5-0.40.10.3-0.5-0.50.5-0.5-0.7-0.70.7-0.7
K content in liver1.21.22.8-0.40.21.3-0.7-0.71.2-1.1-1.0-1.61.7-1.4
Mg content in liver3.33.46.70.3-0.61.3-1.8-1.72.3-2.2-1.3-2.32.6-2.2
Mn content in liver3.23.67.0-0.2-0.21.5-1.6-1.52.0-2.3-2.4-2.42.6-2.1
Na content in liver1.01.13.50.2-0.40.5-0.9-0.71.2-1.0-1.9-1.01.2-1.3
Rb content in liver1.21.53.00.6-1.10.0-1.4-1.51.7-1.3-1.0-1.11.2-1.3
Se content in liver0.70.91.90.7-1.1-0.4-1.2-1.00.9-1.2-1.4-0.50.7-0.4
Sr content in liver1.21.12.0-0.71.0-0.01.31.2-1.41.10.61.1-1.01.0
Zn content in liver1.11.22.8-0.30.21.1-1.0-0.91.0-1.4-0.9-1.51.7-1.1
Bone: minimum diameter8.115.135.3-5.95.73.84.94.8-3.23.83.40.2-0.60.2
Time in familiar zone, hab. session 11.71.64.1-1.71.51.21.41.5-0.71.42.00.0-0.2-0.2
Time in novel zone, hab. session 10.90.92.31.1-1.0-0.9-1.1-1.20.4-1.1-1.5-0.00.20.3
Total zone transitions, hab. session 10.70.92.90.5-0.2-1.30.10.3-1.30.2-0.81.2-1.21.7
Total locomotion distance, hab. session 10.71.02.80.4-0.5-1.6-0.4-0.3-0.8-0.0-1.71.5-1.01.2
Locomotion velocity, hab. session 10.71.02.40.6-0.6-1.6-0.3-0.3-0.8-0.0-1.51.4-1.01.3
Time in familiar zone, hab. session 21.41.53.3-1.81.60.91.51.5-1.01.41.20.5-0.50.0
Time in novel zone, hab. session 22.62.64.51.7-1.7-0.4-2.1-2.01.7-2.1-1.5-1.21.3-0.8
Total zone transitions, hab. session 21.01.33.91.0-0.6-1.8-0.4-0.2-1.2-0.2-0.91.3-1.22.0
Total locomotion distance, hab. session 21.41.85.51.3-1.2-2.3-0.8-0.7-0.8-0.2-1.41.8-1.31.6
Locomotion velocity, hab. session 21.41.95.51.6-1.5-2.3-1.1-1.0-0.4-0.5-1.51.6-1.11.4
Novel to familiar place preference ratio2.42.55.1-1.82.31.32.22.1-1.61.81.40.4-0.60.4
Novelty place preference1.61.63.4-1.51.81.11.81.7-1.31.31.10.2-0.40.4
Time in novel zone, NPP test1.41.43.2-1.51.81.11.71.6-1.11.20.80.2-0.30.2
Total zone transitions, NPP test0.81.14.40.7-0.6-1.5-1.2-0.9-0.3-0.9-2.11.0-0.30.6
Total locomotion distance, NPP test1.01.44.10.9-1.0-1.7-1.5-1.40.0-1.1-2.01.1-0.20.5
Locomotion velocity, NPP test1.11.54.21.0-1.0-2.1-1.2-1.1-0.4-0.7-1.81.5-0.70.9
Intraocular pressure0.81.12.7-0.91.3-0.11.11.1-1.70.90.11.2-0.90.9
Delta distance traveled before/after self-admin0.50.61.20.9-0.9-1.0-1.1-0.90.3-0.8-0.80.3-0.0-0.1
Delta ambulatory time before/after self-admin0.10.10.5-0.30.20.4-0.3-0.00.2-0.3-0.1-0.40.4-0.7
Parametrial fat weight0.71.54.80.1-0.31.3-0.5-0.61.8-0.80.2-1.51.6-2.2
Pavlov. Cond. lever latency1.72.26.00.3-0.41.2-1.1-1.22.1-1.20.4-1.82.0-2.5
Pavlov. Cond. magazine entry latency0.81.12.1-1.41.10.21.31.2-1.31.20.20.6-0.90.9
Pavlov. Cond. change in total contacts1.61.73.9-0.91.0-0.41.41.4-2.01.4-0.11.1-1.51.9
Pavlov. Cond. index score1.21.63.1-1.21.0-0.31.41.4-1.81.4-0.11.1-1.41.6
Pavlov. Cond. latency score1.52.04.1-1.00.9-0.61.51.5-2.01.5-0.01.4-1.72.0
Pavlov. Cond. lever contacts1.82.16.20.00.3-1.21.11.2-2.11.2-0.11.6-2.02.5
Pavlov. Cond. magazine entry number0.50.71.41.2-0.9-0.4-1.1-1.10.9-1.0-0.0-0.30.6-0.5
Pavlov. Cond. intertrial magazine entries3.13.78.4-2.62.91.02.32.3-2.32.11.21.2-1.00.8
Pavlov. Cond. lever-magazine prob. diff.1.11.32.8-1.21.0-0.21.31.3-1.71.2-0.21.0-1.31.5
Pavlov. Cond. response bias0.60.71.6-0.80.7-0.10.91.0-1.30.8-0.40.6-0.91.2
Pavlov. Cond. lever latency0.81.13.41.8-1.8-1.5-0.5-0.50.3-0.00.50.7-0.90.9
Pavlov. Cond. magazine entry latency0.00.10.3-0.30.00.0-0.1-0.10.30.10.10.20.1-0.6
Pavlov. Cond. change in total contacts0.50.72.5-1.51.61.20.70.7-0.40.40.0-0.30.5-0.7
Pavlov. Cond. index score0.70.92.8-1.71.61.20.80.9-0.50.50.0-0.20.4-0.6
Pavlov. Cond. latency score0.60.82.7-1.61.61.10.70.8-0.40.50.0-0.10.4-0.7
Pavlov. Cond. lever contacts0.40.51.7-1.21.30.90.30.3-0.4-0.1-0.8-0.40.6-0.5
Pavlov. Cond. magazine entry number0.00.00.20.1-0.00.2-0.0-0.00.0-0.20.0-0.50.20.2
Pavlov. Cond. intertrial magazine entries0.30.41.2-1.11.01.10.50.6-0.10.10.3-0.60.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.70.82.8-1.71.61.20.80.8-0.40.50.0-0.20.5-0.7
Pavlov. Cond. response bias0.40.51.7-1.31.21.00.30.4-0.20.0-0.4-0.50.6-0.7
Time in closed arm before self-admin0.91.02.20.5-0.2-1.5-0.10.2-1.10.2-1.11.5-1.11.4
Time in closed arm after self-admin0.10.10.30.20.1-0.20.40.5-0.50.30.00.4-0.40.5
Time in open arm before self-admin1.01.13.60.3-0.2-0.51.11.0-0.71.31.90.9-1.30.9
Time in open arm after self-admin0.20.21.00.0-0.1-0.20.40.3-0.30.61.00.4-0.60.3
Bone: periosteal estimation6.513.535.2-5.95.64.04.54.4-2.73.52.7-0.1-0.1-0.5
Bone: periosteal perimeter5.69.323.9-4.94.53.23.83.8-2.42.92.2-0.1-0.3-0.2
Bone: post-yield work1.82.55.4-2.02.31.92.02.0-1.21.51.6-0.4-0.10.1
Progressive ratio test 1 active lever presses1.21.33.60.9-0.7-1.9-0.4-0.5-0.9-0.2-1.81.4-1.11.3
Progressive ratio test 1 breakpoint1.31.33.30.5-0.4-1.8-0.1-0.2-1.20.1-1.81.5-1.21.5
Progressive ratio test 1 inactive lever presses1.01.12.9-0.40.7-0.90.70.7-1.70.4-1.11.3-0.91.4
Progressive ratio test 2 active lever presses0.10.10.50.4-0.2-0.3-0.2-0.30.0-0.2-0.70.20.10.0
Progressive ratio test 2 breakpoint0.10.10.70.4-0.2-0.2-0.3-0.40.1-0.3-0.80.10.2-0.1
Progressive ratio test 2 inactive lever presses0.20.20.6-0.30.70.70.30.2-0.0-0.20.0-0.40.7-0.3
Incentive Sensitization - Responses0.20.20.8-0.00.20.80.1-0.00.6-0.1-0.0-0.50.7-0.9
Incentive Sensitization - Breakpoint0.30.31.00.00.20.80.0-0.10.7-0.1-0.0-0.50.7-1.0
Sum of active levers in priming session hrs 5-60.50.51.0-0.20.1-0.60.70.6-0.80.80.81.0-0.90.8
Progressive ratio0.10.20.5-0.20.00.70.30.20.50.20.5-0.40.3-0.4
Food seeking constrained by brief footshock0.40.41.3-0.50.71.10.50.6-0.00.21.0-1.00.4-0.3
Seeking ratio, punishment vs. effort0.00.00.20.10.3-0.2-0.00.1-0.5-0.1-0.1-0.1-0.20.3
Retroperitoneal fat weight3.09.920.70.4-0.0-2.82.72.4-3.73.32.83.9-4.64.5
Reaction time number correct0.60.81.40.1-0.20.6-0.9-1.01.0-1.2-0.7-1.21.2-1.0
Reaction time mean minus median0.30.42.21.0-0.8-0.20.30.30.10.41.50.0-0.50.5
Reaction time mean minus median AUC0.30.51.40.5-0.30.6-0.4-0.50.9-0.60.6-1.20.8-0.6
Reaction time num false alarms2.22.98.5-2.92.60.81.92.0-2.01.70.30.9-0.80.7
Reaction time num false alarms AUC2.12.98.7-3.02.71.21.92.0-1.91.60.40.5-0.50.4
Reaction time trials correct on left0.60.81.40.1-0.20.6-0.9-1.01.0-1.2-0.7-1.21.2-1.0
Reaction time trials on left0.60.81.60.0-0.10.6-0.9-1.01.0-1.1-0.6-1.31.2-1.0
Reaction time mean0.40.61.80.6-0.80.5-0.5-0.51.3-0.60.3-1.10.9-1.0
Reaction time mean AUC0.50.61.70.9-1.00.2-0.7-0.71.3-0.60.2-0.90.8-0.8
Median of all reaction times0.60.92.30.3-0.60.7-0.7-0.71.5-0.8-0.1-1.31.2-1.3
Reaction time omissions0.30.41.40.4-0.30.6-0.4-0.30.7-0.51.2-1.20.7-0.3
Reaction time false alarm rate2.12.96.1-2.52.30.62.02.2-2.11.90.81.1-1.10.9
Reaction time premature initiation rate2.33.05.0-1.91.80.02.12.1-2.12.21.01.8-1.61.2
Reaction time premature initiations0.91.23.2-1.81.60.61.31.3-1.11.20.40.7-0.50.3
Std. dev. reaction times0.50.71.91.0-0.90.4-0.4-0.41.1-0.41.4-1.00.7-0.6
Reaction time trials completed0.60.81.60.0-0.10.6-0.9-1.01.0-1.1-0.6-1.31.2-1.0
Reaction time trials AUC0.60.91.60.1-0.30.6-0.9-1.11.1-1.2-0.7-1.31.2-1.1
Run reversals in cocaine runway, females4.34.19.71.6-1.2-2.41.41.4-1.72.01.52.7-3.12.4
Run reversals in cocaine runway, males0.20.20.5-0.30.30.70.50.50.20.20.4-0.20.2-0.7
Latency to leave start box in cocaine runway2.22.47.31.7-1.9-2.7-1.2-1.20.0-0.4-2.01.8-1.30.7
Latency to leave start box in cocaine runway, F1.92.16.70.9-1.3-2.6-0.4-0.4-0.80.4-1.52.2-2.01.3
Latency to leave start box in cocaine runway, M1.81.84.12.0-1.9-1.7-1.5-1.50.8-1.1-1.40.4-0.10.2
Std. dev. time between licks in bursts0.70.82.31.3-1.5-1.4-0.9-0.80.3-0.5-0.60.5-0.50.7
Total sessions with >9 infusions0.40.42.9-0.10.2-0.6-0.2-0.3-0.7-0.4-1.70.5-0.20.7
Short access day 1 total inactive lever presses0.20.21.30.2-0.2-0.3-0.3-0.4-0.1-0.3-1.2-0.1-0.0-0.2
Short access day 10 total inactive lever presses0.40.41.5-1.10.90.60.50.5-0.50.51.2-0.1-0.00.3
Short access day 1 total infusions1.01.16.70.4-0.4-1.2-0.9-1.0-0.3-0.9-2.60.5-0.10.5
Short access day 10 total infusions0.80.92.6-0.10.5-1.00.60.6-1.60.4-0.41.3-1.01.5
Short access total infusions0.40.42.8-0.30.4-0.5-0.2-0.3-0.7-0.4-1.70.4-0.00.5
Short access day 1 locomotion0.70.72.3-0.10.1-1.10.10.2-1.20.2-1.50.9-0.91.2
Short access day 10 total locomotion2.22.55.1-0.91.5-0.21.91.9-2.31.71.41.4-1.51.7
Short access total locomotion2.22.36.2-0.50.8-1.21.21.2-2.31.2-0.21.9-1.82.5
One hour access (0.3 mA shock)0.60.71.9-1.41.41.40.10.20.0-0.10.3-0.91.0-0.7
Compulsive drug intake1.41.43.3-1.81.71.81.01.1-0.20.91.5-0.60.6-0.6
One hour access (shock baseline)0.10.10.20.4-0.10.0-0.3-0.30.2-0.5-0.3-0.40.40.1
Social response proportion0.80.91.9-1.11.11.31.31.4-0.30.70.9-0.50.2-0.5
Social responses0.81.02.0-1.41.30.21.21.2-1.31.00.31.0-0.70.3
Social time0.81.12.4-0.81.11.61.31.4-0.30.71.5-0.70.3-0.6
Soleus weight0.51.63.2-0.81.20.31.71.7-1.81.40.60.8-1.21.5
Bone: stiffness0.91.54.9-2.21.61.21.61.5-0.81.30.40.2-0.2-0.2
Tibialis anterior weight1.03.59.40.7-0.3-1.71.51.5-2.31.71.32.1-2.73.1
Time to tail flick, vehicle, before self-admin0.40.42.9-0.00.10.80.20.30.50.31.7-0.50.4-0.4
Time to tail flick, vehicle, after self-admin1.31.43.6-1.31.41.91.41.30.11.01.4-0.50.7-0.8
Time to tail flick, test, before self-admin2.92.86.3-1.41.71.72.32.5-0.92.12.50.1-0.6-0.1
Time to tail flick, test, after self-admin1.21.22.7-1.51.61.71.11.2-0.20.71.3-0.50.6-0.7
Delta time to tail flick, vehicle, before/after SA0.90.92.8-1.11.01.70.40.30.6-0.1-0.1-1.11.2-1.4
Delta time to tail flick, test, before/after SA0.90.92.2-1.00.81.3-0.3-0.40.7-0.70.1-1.31.5-0.9
Tibia length1.13.25.9-0.30.5-1.11.91.9-2.22.20.72.3-2.42.3
Ambulatory time before self-admin0.40.41.00.5-0.5-0.70.60.5-0.20.5-0.71.0-0.70.4
Ambulatory time after self-admin0.20.20.5-0.20.0-0.30.50.7-0.30.6-0.30.7-0.6-0.0
Bone: tissue strength1.71.73.61.5-1.2-0.7-1.7-1.61.2-1.6-1.9-0.40.9-0.7
Total heroin consumption0.00.10.2-0.40.30.30.30.2-0.10.2-0.1-0.00.1-0.0
Bone: trabecular number2.53.910.0-0.70.82.6-0.9-1.01.8-1.8-1.2-3.22.9-2.6
Bone: trabecular spacing1.01.34.10.3-1.0-1.90.20.3-0.61.00.52.0-1.71.2
Bone: trabecular thickness1.11.33.7-1.81.91.81.00.9-0.50.40.6-0.90.7-0.6
Bone: trabecular tissue density0.40.52.10.5-0.8-1.20.00.1-0.00.6-0.21.4-0.90.2
Water consumed over 24 hours1.51.85.11.5-1.7-2.2-1.2-1.1-0.1-0.6-1.51.3-0.91.2
Number of responses in last shaping day1.21.33.31.3-0.8-1.80.30.2-1.00.3-0.61.7-1.31.4