Hub : Genes

Pdcd4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Pdcd4 0.29 0.12 0.0e+00 0.22 0.22 0.24 0.24 4.0e-25 1.6e-25 5.9e-28 1.3e-27
2 OFC isoform ratio XR_351142.4 0.22 0.14 3.0e-03 0.09 0.08 0.11 0.1 4.2e-03 5.2e-03 1.6e-03 2.2e-03
3 Adipose gene expression Pdcd4 0.18 0.08 4.9e-14 0.07 0.09 0.09 0.08 1.5e-08 1.0e-09 8.2e-10 1.2e-09
4 BLA gene expression Pdcd4 0.33 0.11 6.1e-16 0.28 0.3 0.31 0.3 2.3e-15 1.4e-16 7.6e-17 3.0e-16
5 pVTA gene expression Pdcd4 0.4 0.12 2.8e-16 0.26 0.37 0.35 0.36 1.7e-11 6.8e-17 4.6e-16 1.6e-16
6 RMTg alternative TSS NM_022265.3 0.9 0.05 5.2e-03 0.02 -0.01 0.04 -0 8.8e-02 6.8e-01 2.8e-02 4.3e-01
7 LHb gene expression Pdcd4 0.46 0.13 6.3e-10 0.34 0.36 0.32 0.36 5.0e-09 2.1e-09 2.9e-08 2.6e-09
8 Brain gene expression Pdcd4 0.49 0.12 0.0e+00 0.47 0.54 0.54 0.53 2.2e-48 7.0e-60 7.4e-59 3.4e-58
9 LHb isoform ratio XR_351142.4 0.25 0.13 6.8e-04 0.06 0.1 0.05 0.09 1.7e-02 1.9e-03 3.1e-02 3.2e-03
10 PL gene expression Pdcd4 0.35 0.09 0.0e+00 0.41 0.45 0.45 0.45 3.7e-48 9.6e-55 3.2e-55 5.9e-55
11 Adipose alternative TSS XM_006231615.4 0.22 0.09 8.1e-08 0.08 0.05 0.05 0.07 5.3e-09 1.9e-06 2.5e-06 3.3e-08
12 Adipose alternative TSS XM_006231616.4 0.22 0.09 8.5e-08 0.08 0.05 0.05 0.07 6.1e-09 2.1e-06 2.0e-06 3.9e-08
13 OFC gene expression Pdcd4 0.69 0.11 2.2e-16 0.46 0.51 0.44 0.5 3.0e-12 4.8e-14 7.2e-12 8.4e-14
14 Eye gene expression Pdcd4 0.58 0.17 9.0e-05 0.2 0.16 0.15 0.19 4.5e-04 1.8e-03 2.6e-03 8.3e-04
15 Liver gene expression Pdcd4 0.36 0.11 0.0e+00 0.33 0.32 0.32 0.32 1.3e-37 1.4e-35 9.0e-37 1.0e-36
16 Adipose mRNA stability Pdcd4 0.17 0.08 1.0e-05 0.04 0.03 0.04 0.04 2.6e-05 6.2e-04 1.9e-05 1.4e-05
17 IL gene expression Pdcd4 0.47 0.13 5.7e-11 0.42 0.42 0.41 0.43 2.1e-11 3.3e-11 8.1e-11 1.8e-11
18 Brain mRNA stability Pdcd4 0.12 0.06 2.4e-10 0.1 0.13 0.14 0.13 1.4e-09 5.3e-12 3.2e-13 1.9e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.81.42.81.7-1.7-1.21.5-1.6-1.4-1.5-1.41.41.20.3-0.3-0.90.80.9-0.1-0.70.2
Area under the delay curve0.91.02.21.5-1.2-1.21.4-1.3-0.8-1.1-1.21.20.90.7-0.7-0.70.50.50.4-0.60.5
BMI with tail2.06.311.83.0-3.4-2.43.1-2.9-3.2-3.2-2.72.82.60.5-0.5-2.32.52.40.3-2.7-1.3
BMI without tail2.24.57.52.7-2.5-2.62.6-2.7-1.8-2.4-2.52.52.41.3-1.3-2.11.91.80.9-1.8-0.4
Body weight2.711.428.64.2-5.3-2.83.9-4.2-4.4-4.5-3.53.73.5-0.80.8-3.03.13.0-1.1-3.2-0.8
Weight adjusted by age0.50.51.50.9-1.2-0.70.1-1.1-1.2-1.0-0.60.70.6-0.30.3-0.80.60.7-0.4-0.6-0.1
Bone surface0.20.41.00.8-0.8-0.40.8-0.6-1.0-0.8-0.80.70.7-0.20.2-0.50.70.7-0.2-0.4-0.4
Bone volume0.91.54.11.6-2.0-0.91.5-1.5-1.7-1.6-1.31.31.2-0.50.5-0.90.91.0-0.8-0.80.1
Breakpoint value in progressive ratio session0.20.21.00.5-0.4-0.61.0-0.6-0.1-0.5-0.60.60.40.6-0.6-0.20.00.00.30.00.4
Number of licking bursts0.50.62.3-0.0-0.90.60.2-0.1-0.1-0.20.2-0.2-0.3-1.21.20.6-0.7-0.6-1.50.41.4
Context. condit. distance diff. score0.91.11.9-1.41.21.2-1.21.31.21.31.2-1.2-1.1-0.50.50.9-0.9-0.9-0.40.70.8
Locomotion velocity, session 11.92.13.3-1.31.41.1-1.71.31.81.61.6-1.5-1.6-0.30.31.7-1.6-1.8-0.51.71.7
Locomotion distance, session 10.50.61.6-0.80.31.1-0.70.80.50.60.8-0.8-0.7-1.31.30.6-0.5-0.5-1.10.50.3
Locomotion velocity, session 20.20.31.0-0.50.10.7-0.50.5-0.00.20.3-0.4-0.2-1.01.0-0.10.40.4-0.7-0.1-0.7
Locomotion distance, session 20.91.25.4-0.6-0.61.4-0.40.6-0.10.10.7-0.7-0.7-2.32.30.8-0.5-0.7-2.30.70.4
Locomotion velocity, session 31.72.02.8-1.61.01.7-1.41.41.31.31.6-1.5-1.5-1.51.51.4-1.3-1.5-1.41.11.3
Locomotion distance, session 33.74.16.7-2.00.92.3-2.11.71.71.82.1-2.1-1.9-2.62.61.8-1.8-1.8-2.61.72.2
Stereotopy head waving bouts, day 30.30.41.70.00.6-0.30.20.0-0.4-0.1-0.20.30.21.1-1.1-0.10.30.21.2-0.2-1.3
Stereotopy head waving duration, day 30.50.62.6-0.21.1-0.3-0.10.30.30.40.00.0-0.11.6-1.60.2-0.2-0.21.60.1-0.9
Locomotion velocity, session 71.11.21.7-1.10.81.1-1.21.00.91.11.3-1.2-1.3-0.80.81.3-1.2-1.3-1.01.31.0
Locomotion distance, session 71.82.23.8-1.70.72.0-1.51.61.11.31.6-1.6-1.5-1.91.91.4-1.2-1.2-1.81.20.8
Stereotopy head waving bouts, day 70.50.61.0-0.70.90.7-0.80.80.60.80.8-0.8-0.8-0.20.21.0-0.8-1.0-0.21.00.6
Stereotopy head waving duration, day 70.30.40.9-0.40.80.4-0.60.50.40.60.6-0.6-0.70.1-0.10.9-0.8-0.90.00.90.6
Locomotion velocity, session 80.20.20.3-0.60.50.5-0.50.50.50.50.5-0.5-0.4-0.40.40.3-0.2-0.3-0.30.2-0.2
Locomotion distance, session 81.01.53.3-1.40.51.7-1.11.31.01.01.2-1.3-1.1-1.81.81.0-0.8-1.0-1.70.71.0
Degree of sensitization distance0.60.62.30.40.2-0.80.6-0.2-0.2-0.3-0.60.60.51.5-1.5-0.40.40.51.5-0.3-1.0
Degree of sensitization stereotypy1.51.72.4-1.21.11.4-1.31.31.01.21.4-1.4-1.4-1.01.01.5-1.4-1.5-1.11.51.2
Conditioned locomotion1.61.84.5-1.20.31.7-1.31.20.60.91.3-1.4-1.2-2.12.11.2-0.9-1.0-2.11.11.0
Cocaine response after cond. corrected0.70.83.3-1.11.80.5-0.61.11.01.10.6-0.6-0.61.0-1.00.4-0.4-0.31.30.2-0.8
Cocaine response after cond. not corrected1.31.44.9-1.82.21.1-1.11.71.31.51.1-1.1-1.10.6-0.60.8-0.8-0.61.00.5-0.8
Cocaine response before conditioning0.30.40.7-0.80.60.8-0.70.80.30.60.7-0.7-0.8-0.40.40.7-0.6-0.4-0.30.4-0.0
Saline control response0.40.51.5-1.01.20.9-1.01.10.40.80.8-0.8-0.8-0.20.20.6-0.4-0.40.10.7-0.5
Bone: connectivity density0.40.60.91.0-0.8-0.90.8-0.9-0.7-0.7-1.00.90.90.5-0.5-0.90.90.90.5-0.7-0.2
Bone: cortical apparent density0.81.02.1-1.30.81.2-1.51.10.71.01.3-1.2-1.0-1.31.30.5-0.5-0.4-0.90.4-0.3
Bone: cortical area1.11.76.0-0.8-0.21.9-0.31.0-0.60.10.8-0.8-1.0-2.32.31.4-1.0-0.9-2.51.10.5
Bone: cortical porosity0.30.31.70.40.4-0.50.5-0.2-0.4-0.3-0.50.50.21.3-1.30.1-0.00.01.10.3-0.0
Bone: cortical porosity0.10.20.60.30.1-0.30.5-0.2-0.3-0.3-0.40.30.10.7-0.70.2-0.2-0.20.50.40.3
Bone: cortical thickness2.13.410.3-1.70.42.8-1.11.8-0.20.71.5-1.6-1.7-3.23.21.9-1.3-1.1-3.01.40.4
Bone: cortical thickness1.82.17.5-1.30.02.2-0.81.3-0.20.51.1-1.2-1.2-2.72.71.2-0.8-0.7-2.50.8-0.0
Bone: cortical tissue density0.70.92.0-1.20.81.1-1.41.00.81.01.3-1.2-0.9-1.21.20.4-0.4-0.4-0.80.3-0.3
Condit. Reinf. active minus inactive responses1.61.83.2-1.31.50.9-1.41.31.81.61.4-1.3-1.50.4-0.41.6-1.7-1.70.11.51.1
Condit. Reinf. active-inactive response ratio0.91.02.1-0.81.40.2-0.70.91.41.10.7-0.7-0.81.2-1.20.9-1.1-1.11.10.80.4
Condit. Reinf. active responses2.02.54.5-1.41.51.3-1.61.61.71.61.7-1.6-1.8-0.20.22.1-2.0-2.1-0.52.01.7
Condit. Reinf. inactive responses0.60.71.8-0.60.50.9-0.60.70.40.50.7-0.7-0.9-0.60.61.2-1.0-1.1-0.91.21.3
Incentive salience index mean2.02.45.0-1.41.71.0-1.61.52.21.81.6-1.6-1.70.3-0.31.7-1.9-2.00.01.81.5
Condit. Reinf. lever presses0.70.92.7-0.60.60.4-0.90.51.61.00.9-0.9-0.9-0.00.00.9-1.3-1.4-0.41.11.5
Condit. Reinf. active minus inactive responses4.25.19.9-1.92.61.1-2.31.92.72.52.2-2.1-2.51.2-1.22.8-3.1-3.10.53.01.8
Condit. Reinf. active-inactive response ratio4.34.57.6-2.12.71.3-2.12.12.72.52.2-2.1-2.41.0-1.02.6-2.7-2.80.62.41.3
Condit. Reinf. active responses2.73.77.8-1.61.90.9-1.91.62.22.01.9-1.8-2.20.8-0.82.5-2.7-2.80.12.71.8
Condit. Reinf. inactive responses0.20.31.2-0.10.1-0.0-0.60.10.40.30.4-0.3-0.50.1-0.10.6-0.7-0.9-0.31.01.1
Condit. Reinf. lever presses3.75.08.2-2.22.02.0-2.32.22.42.32.4-2.3-2.6-0.80.82.8-2.8-2.9-1.22.71.9
Condit. Reinf. lever reinforcers received2.94.17.9-1.82.21.1-2.11.82.32.22.0-1.9-2.30.9-0.92.6-2.7-2.80.22.71.8
Conditioned reinforcement - actives1.51.53.01.2-0.5-1.61.1-1.1-0.8-1.0-1.31.31.21.7-1.7-1.11.21.11.6-0.7-0.9
Conditioned reinforcement - inactives0.20.20.70.6-0.5-0.20.1-0.6-0.5-0.5-0.30.30.3-0.50.50.0-0.0-0.1-0.80.70.8
Conditioned locomotion3.84.55.72.4-2.0-2.42.3-2.3-2.2-2.3-2.32.32.31.2-1.2-2.32.22.31.3-2.3-2.0
Patch foraging indifference point 0 sec0.40.63.8-0.70.61.20.51.0-1.4-0.3-0.1-0.1-0.2-0.80.80.60.20.3-0.40.0-2.0
Patch foraging indifference point AUC1.21.43.9-0.8-0.01.5-0.60.80.30.50.9-0.9-1.1-1.61.61.5-1.3-1.3-2.01.41.4
Delay disc. indifference point, 0s delay0.60.61.51.1-1.0-0.91.1-1.2-1.0-1.0-0.90.90.80.2-0.2-0.70.50.5-0.1-0.3-0.1
Delay disc. indifference point, 16s delay0.40.41.10.8-0.3-0.90.5-0.6-0.3-0.4-0.60.60.41.1-1.1-0.30.10.10.9-0.30.2
Delay disc. indifference point, 2s delay0.30.31.00.9-1.0-0.60.6-0.9-0.3-0.6-0.50.50.5-0.30.3-0.40.10.1-0.5-0.10.5
Delay disc. indifference point, 24s delay1.00.92.11.5-1.3-1.11.2-1.2-0.9-1.1-1.21.10.90.7-0.7-0.60.50.50.2-0.21.1
Delay disc. indifference point, 4s delay0.20.21.20.7-0.6-0.50.3-0.60.3-0.2-0.30.20.20.1-0.10.0-0.2-0.3-0.20.21.1
Delay disc. indifference point, 8s delay1.41.43.41.6-1.4-1.21.9-1.5-1.3-1.5-1.51.51.10.9-0.9-0.80.80.70.6-1.00.2
Indifference point function ln k0.40.51.60.30.2-0.70.3-0.4-0.4-0.2-0.40.50.51.1-1.1-0.70.60.81.3-0.8-1.2
Indifference point function log k0.40.51.60.30.2-0.70.3-0.4-0.4-0.2-0.40.50.51.1-1.1-0.70.60.81.3-0.8-1.2
Patch foraging total patch changes 0 sec0.40.62.2-0.70.51.30.31.0-1.3-0.20.1-0.2-0.4-1.01.00.8-0.0-0.0-0.80.4-1.5
Patch foraging total patch changes 12 sec0.81.03.0-0.80.21.5-0.10.8-0.10.20.6-0.7-0.8-1.51.51.3-0.9-1.0-1.71.20.6
Patch foraging total patch changes 18 sec1.01.33.1-1.00.71.7-0.31.2-0.30.40.9-0.9-1.2-1.31.31.8-1.4-1.3-1.51.60.3
Patch foraging total patch changes 24 sec0.50.72.0-0.3-0.11.10.30.5-0.3-0.10.3-0.3-0.6-1.11.11.2-1.0-1.0-1.41.01.0
Patch foraging total patch changes 6 sec0.60.83.2-0.5-0.11.60.50.8-1.1-0.4-0.0-0.2-0.3-1.81.80.8-0.0-0.2-1.60.4-0.4
Patch foraging time to switch 0 sec0.81.33.01.0-0.2-1.50.9-1.00.0-0.5-1.11.01.21.6-1.6-1.31.11.11.7-1.0-0.2
Patch foraging water rate 0 sec0.40.61.9-0.5-0.21.0-0.50.5-0.60.00.6-0.5-0.7-1.31.30.8-0.5-0.5-1.40.5-0.2
Patch foraging water rate 12 sec0.40.61.51.0-0.8-0.81.0-0.7-1.2-0.9-0.90.90.70.6-0.6-0.50.60.80.5-0.7-0.9
Patch foraging water rate 18 sec0.30.30.70.5-0.6-0.40.6-0.5-0.8-0.6-0.60.60.60.0-0.0-0.60.70.80.2-0.8-0.6
Patch foraging water rate 24 sec0.40.51.30.7-1.0-0.41.0-0.8-1.1-1.0-0.80.80.6-0.10.1-0.60.60.6-0.0-1.0-0.8
Patch foraging water rate 6 sec0.40.62.90.6-0.6-0.40.5-0.5-1.4-0.8-0.60.60.60.1-0.1-0.60.80.80.2-0.6-1.7
Seeking ratio, delayed vs. immediate footshock0.60.71.30.6-0.9-0.21.0-0.6-1.1-1.0-0.80.70.8-0.60.6-0.80.91.0-0.3-1.1-0.8
Distance traveled before self-admin0.70.82.1-0.90.41.0-1.20.70.80.81.0-1.0-0.6-1.51.50.2-0.2-0.4-1.20.60.1
Distance traveled after self-admin1.01.22.40.8-1.2-0.60.9-0.9-1.2-1.1-0.90.91.3-0.70.7-1.51.51.4-0.2-1.5-1.2
Extensor digitorum longus weight0.41.66.60.1-1.10.7-0.4-0.30.30.00.7-0.6-0.6-2.02.00.9-1.2-1.2-2.61.12.4
Bone: elastic displacement0.10.10.60.30.2-0.50.2-0.30.0-0.1-0.20.30.20.8-0.8-0.2-0.00.00.7-0.00.1
Bone: elastic work0.30.40.80.7-0.8-0.50.7-0.9-0.9-0.9-0.60.70.7-0.30.3-0.70.50.6-0.2-0.7-0.5
Bone: endosteal estimation1.22.64.81.9-1.7-1.82.2-1.9-1.8-1.9-2.02.01.81.2-1.2-1.41.31.31.0-1.4-0.9
Bone: endosteal perimeter0.51.03.21.1-1.8-0.41.1-1.1-1.3-1.3-0.90.90.8-0.90.9-0.50.60.5-1.2-0.50.0
Epididymis fat weight1.53.413.62.6-3.7-1.72.0-2.6-2.3-2.6-1.71.91.6-0.50.5-1.11.10.8-1.2-1.20.7
Delta time in closed arm before/after self-admin0.30.31.2-0.81.10.7-0.40.70.30.50.2-0.3-0.3-0.10.10.00.20.20.20.4-0.9
Delta time in open arm before/after self-admin0.50.51.11.0-0.6-1.10.7-0.9-0.7-0.7-0.70.80.61.0-1.0-0.30.20.10.7-0.30.1
Diff in mean of infusions in LGA sessions2.22.45.6-2.02.30.9-1.01.72.42.01.5-1.4-1.51.3-1.31.4-1.7-1.81.30.8-0.2
Delay discount exponential model param0.91.02.3-1.51.41.2-1.41.40.81.21.2-1.2-0.9-0.60.60.6-0.5-0.4-0.30.5-0.6
Extinction: sum of active levers before priming0.20.20.8-0.20.7-0.10.30.1-0.2-0.0-0.20.2-0.00.9-0.90.1-0.2-0.00.80.2-0.5
Active lever presses in extinction session 61.41.44.0-0.70.11.3-0.90.70.40.61.0-1.0-1.0-1.91.91.0-0.9-0.9-2.01.21.6
Bone: final force0.40.62.30.5-0.90.01.2-0.5-1.5-1.1-0.90.80.7-0.50.5-0.40.60.8-0.4-0.9-0.8
Bone: final moment0.60.93.00.8-1.1-0.21.4-0.7-1.7-1.4-1.11.00.9-0.30.3-0.60.80.9-0.2-1.0-0.8
Food consumed during 24 hour testing period0.40.50.90.8-0.6-0.70.9-0.8-0.8-0.7-0.90.80.80.5-0.5-0.80.61.00.4-0.5-0.3
Glucose1.62.37.91.4-2.8-0.41.3-1.6-1.9-1.8-1.01.11.2-2.02.0-1.11.11.0-2.1-1.20.2
Heart weight4.05.69.7-3.02.82.9-2.63.11.62.52.8-2.7-2.8-1.31.32.8-2.2-2.2-1.12.20.3
Delay discount hyperbolic model param0.80.92.2-1.51.31.2-1.31.40.71.11.1-1.1-0.9-0.60.60.7-0.4-0.4-0.30.5-0.6
Intermittent access intake day 1-15 change2.22.23.92.0-1.3-2.01.7-1.8-1.4-1.6-1.71.71.61.6-1.6-1.21.11.11.2-0.5-0.2
Intermittent access intake escalation2.22.24.22.1-1.5-1.81.7-1.8-1.6-1.7-1.81.71.71.1-1.1-1.41.41.40.8-0.6-0.4
Intermittent access intake escalation 23.63.66.12.5-2.0-2.42.2-2.3-1.9-2.1-2.12.22.21.4-1.4-1.91.71.71.1-1.4-0.5
Intermitt. access day 1 inactive lever presses0.90.93.70.0-1.00.6-0.1-0.3-0.1-0.30.3-0.2-0.4-1.51.50.7-1.0-0.9-1.90.51.9
Intermitt. access day 15 inactive lever presses0.20.21.4-0.20.10.1-0.4-0.00.90.40.3-0.3-0.3-0.10.10.3-0.7-0.7-0.20.31.2
Intermitt. access escalation Index0.60.51.10.8-1.0-0.40.8-0.9-0.8-0.9-0.70.80.8-0.50.5-0.80.80.6-0.4-0.6-0.4
Intermittent access day 1 total infusions0.20.20.80.20.2-0.40.2-0.20.20.1-0.10.1-0.20.9-0.90.4-0.6-0.50.50.50.6
Intermittent access day 15 total infusions1.21.32.81.7-1.0-1.71.4-1.5-0.8-1.1-1.31.31.01.5-1.5-0.60.40.41.0-0.10.5
Intermittent access terminal intake (last 3 days)2.02.14.72.0-1.4-2.21.8-1.9-0.8-1.4-1.61.61.41.9-1.9-1.00.60.61.4-0.80.4
Intermittent access total infusions1.11.22.71.5-1.0-1.61.3-1.4-0.7-1.1-1.21.20.91.5-1.5-0.60.40.31.0-0.30.3
Intermittent access day 1 locomotion0.10.10.30.2-0.1-0.40.2-0.4-0.0-0.2-0.20.20.20.4-0.4-0.30.10.20.5-0.6-0.4
Intermittent access day 15 total locomotion0.50.61.51.2-1.0-1.00.6-1.0-1.1-0.9-0.80.80.80.4-0.4-0.60.60.70.1-0.1-0.1
Intermittent access total locomotion1.11.31.81.3-1.0-1.41.2-1.3-1.1-1.2-1.21.21.20.8-0.8-1.21.01.10.9-1.2-1.2
Intermittent access standard deviation3.53.78.52.9-2.1-2.52.3-2.3-2.0-2.2-2.42.32.11.5-1.5-1.61.61.40.9-0.70.1
Left kidney weight2.67.212.32.5-3.3-1.52.7-2.6-3.5-3.2-2.62.62.8-1.11.1-3.03.33.3-0.5-3.3-2.9
Right kidney weight1.74.88.42.1-2.9-1.32.4-2.2-2.9-2.7-2.12.22.3-0.80.8-2.32.42.4-0.5-2.7-2.3
Cocaine induced anxiety1.01.14.9-1.10.11.5-0.90.90.30.50.8-0.9-0.5-2.22.2-0.00.30.3-1.5-0.5-0.6
Post-drug Anxiety0.40.52.2-0.8-0.01.1-0.10.70.20.20.5-0.5-0.3-1.51.50.2-0.0-0.0-1.0-0.6-0.3
Baseline Anxiety0.40.41.60.2-0.2-0.20.3-0.2-0.1-0.10.1-0.0-0.40.5-0.51.0-1.2-1.2-0.20.71.3
Tail length0.20.51.80.9-1.3-0.50.4-1.0-0.2-0.6-0.50.50.5-0.60.6-0.3-0.10.0-1.10.41.4
Length with tail0.93.210.32.1-3.2-1.01.7-2.2-2.3-2.3-1.61.71.6-1.51.5-1.41.21.3-1.8-1.20.4
Length without tail0.81.85.70.9-2.10.21.1-0.9-2.4-1.7-0.70.80.7-2.02.0-0.60.90.9-1.9-1.1-0.5
Times rat made contact with spout0.50.62.70.1-1.00.70.1-0.0-1.0-0.50.2-0.1-0.2-1.61.60.3-0.1-0.0-1.60.20.2
Lifetime Intake1.11.22.81.6-0.9-1.71.2-1.3-0.9-1.1-1.31.31.01.6-1.6-0.60.60.51.0-0.10.1
Liver weight, left0.50.83.4-0.1-0.60.9-0.20.3-0.4-0.10.4-0.4-0.5-1.51.50.9-0.5-0.8-1.81.01.2
Liver weight, right3.55.813.63.1-3.7-2.22.8-3.0-3.2-3.2-2.62.72.7-0.20.2-2.22.22.1-0.6-1.9-0.6
Locomotor activity0.30.52.2-0.70.11.2-0.60.8-0.40.20.6-0.6-0.5-1.51.50.40.00.1-1.10.0-0.2
Locomotor testing distance0.30.41.5-0.60.31.0-0.30.7-0.70.00.3-0.4-0.2-1.21.2-0.00.50.5-0.6-0.5-1.0
Locomotor testing rearing0.30.51.60.4-0.1-0.10.6-0.1-1.0-0.6-0.60.50.70.0-0.0-0.81.21.20.5-0.9-1.3
Locomotion in novel chamber0.60.72.1-1.21.51.0-1.21.30.31.00.9-1.0-0.9-0.20.20.6-0.3-0.30.00.5-0.8
Locomotion in novel chamber post-restriction0.20.20.9-0.20.4-0.40.1-0.10.50.30.1-0.0-0.00.8-0.8-0.2-0.2-0.20.9-0.5-0.4
Fecal boli incidents, locomotor time 10.40.51.00.8-0.9-1.00.6-0.9-0.5-0.7-0.70.80.80.6-0.6-0.70.50.40.4-0.4-0.1
Change in fecal boli incidents, locomotor task0.70.61.8-0.60.80.3-0.90.51.31.00.8-0.8-0.80.2-0.20.7-1.0-0.9-0.00.91.0
Time >=10cm from walls, locomotor time 10.30.31.00.6-0.0-0.50.2-0.2-0.4-0.3-0.60.50.60.5-0.5-0.71.00.80.6-0.4-0.5
Bouts of movement, locomotor time 11.51.64.91.4-0.6-1.81.2-1.3-0.9-0.9-1.21.31.02.2-2.2-0.60.30.41.7-0.1-0.7
Total resting periods, locomotor time 11.21.33.41.5-0.9-1.71.1-1.4-0.9-1.0-1.11.21.01.8-1.8-0.60.30.41.3-0.1-0.3
Rest time, locomotor task time 10.30.30.9-0.60.30.7-0.90.70.20.50.7-0.6-0.6-0.40.40.5-0.2-0.3-0.40.60.0
Distance moved, locomotor task time 10.40.51.21.0-1.0-0.70.7-1.1-0.5-0.8-0.70.80.7-0.20.2-0.70.40.4-0.3-0.70.7
Vertical activity count, locomotor time 10.70.71.7-1.10.90.8-1.10.91.31.11.1-1.1-0.9-0.60.60.5-0.7-0.8-0.40.40.2
Time >=10cm from walls, locomotor time 20.70.82.4-0.6-0.01.1-0.70.80.10.40.8-0.8-0.7-1.51.50.8-0.4-0.7-1.50.70.8
Bouts of movement, locomotor time 21.21.36.40.80.2-1.70.1-0.90.5-0.0-0.60.70.62.5-2.5-0.6-0.00.22.1-0.00.3
Total resting periods, locomotor time 21.41.46.40.90.1-1.80.4-1.00.1-0.3-0.91.00.82.5-2.5-0.80.30.42.1-0.2-0.0
Rest time, locomotor task time 21.51.83.91.1-0.9-1.11.2-0.9-1.5-1.3-1.51.41.50.9-0.9-1.52.01.71.1-1.2-1.6
Distance moved, locomotor task time 20.70.81.7-0.90.90.9-0.60.80.90.80.9-0.9-1.1-0.40.41.2-1.3-1.2-0.61.01.0
Vertical activity count, locomotor time 22.32.53.7-1.80.81.9-1.51.71.11.41.8-1.8-1.8-1.81.81.7-1.7-1.5-1.81.40.5
Light reinforcement 10.81.52.6-1.51.41.2-1.21.41.61.51.4-1.4-1.3-0.50.51.3-1.2-1.4-0.41.10.3
Light reinforcement 20.81.12.0-1.31.00.8-1.21.01.41.31.2-1.2-1.1-0.50.51.0-1.2-1.1-0.61.10.5
Bone: marrow area1.22.64.81.9-1.7-1.82.2-1.8-1.8-1.9-2.02.01.81.2-1.2-1.41.31.31.0-1.4-0.9
Bone: maximum diameter0.71.35.4-0.4-0.61.40.00.5-0.8-0.30.5-0.5-0.7-2.12.11.2-0.9-0.9-2.31.00.3
Bone: maximum force0.10.21.20.3-0.50.20.7-0.2-1.1-0.7-0.50.40.3-0.40.4-0.10.20.4-0.3-0.4-0.4
Bone: maximum moment0.20.41.60.6-0.7-0.10.9-0.4-1.3-0.9-0.70.70.5-0.10.1-0.20.40.6-0.2-0.5-0.4
Mean time between licks in bursts1.11.58.10.50.9-1.30.5-0.40.30.1-0.50.50.32.8-2.8-0.1-0.2-0.12.6-0.1-0.1
Mean num. licks in bursts0.40.43.00.30.1-0.40.1-0.1-0.9-0.4-0.30.40.50.4-0.4-0.61.00.90.7-0.5-1.7
Cd content in liver3.23.510.5-2.53.21.8-1.82.72.02.41.7-1.9-1.90.8-0.81.8-1.5-1.51.11.5-0.5
Co content in liver0.20.32.1-0.70.80.6-0.40.7-0.20.30.3-0.3-0.2-0.10.1-0.00.30.20.4-0.3-1.5
Cu content in liver0.70.81.31.1-1.2-1.01.0-1.1-1.0-1.1-0.91.01.10.2-0.2-1.10.90.80.1-0.9-0.6
Fe content in liver0.91.02.4-1.41.11.6-0.81.50.30.91.1-1.1-1.1-0.80.81.2-0.9-0.9-0.60.8-0.7
K content in liver1.11.12.41.5-1.5-1.31.3-1.5-0.9-1.2-1.21.21.20.4-0.4-1.10.80.70.1-0.70.3
Mg content in liver0.60.61.91.2-1.4-1.01.0-1.3-0.4-0.9-0.80.90.80.1-0.1-0.50.10.0-0.3-0.20.9
Mn content in liver1.31.52.2-1.20.81.0-1.51.01.41.31.4-1.4-1.3-0.80.81.2-1.4-1.4-1.01.41.0
Na content in liver0.70.81.9-0.50.70.1-1.00.41.31.00.8-0.8-0.80.4-0.40.9-1.2-1.2-0.01.41.3
Rb content in liver0.50.63.30.20.7-0.70.3-0.10.60.3-0.30.30.11.8-1.80.1-0.3-0.41.60.30.3
Se content in liver0.50.61.70.50.1-0.80.6-0.4-0.3-0.4-0.70.70.61.2-1.2-0.70.60.61.3-0.7-1.1
Sr content in liver2.82.66.41.30.0-2.21.0-1.4-0.3-0.7-1.31.41.52.4-2.4-1.81.31.32.5-1.4-2.0
Zn content in liver0.50.51.6-0.70.60.3-1.20.51.31.01.0-0.9-0.7-0.30.30.3-0.7-0.7-0.30.70.6
Bone: minimum diameter0.10.20.90.3-0.80.20.6-0.4-0.6-0.6-0.20.30.0-0.70.70.3-0.4-0.3-1.00.20.4
Time in familiar zone, hab. session 11.51.43.40.8-0.1-1.30.9-0.8-0.3-0.6-1.01.01.21.3-1.3-1.41.31.11.7-1.4-1.8
Time in novel zone, hab. session 11.21.24.1-0.4-0.41.0-0.60.30.20.30.8-0.7-0.9-1.41.41.2-1.4-1.1-1.91.22.0
Total zone transitions, hab. session 11.31.85.4-1.10.01.8-1.11.20.10.61.3-1.3-1.3-2.32.31.3-0.9-0.9-2.31.10.4
Total locomotion distance, hab. session 10.50.61.2-0.70.21.0-0.60.80.10.50.8-0.8-0.9-0.90.91.1-0.9-0.8-1.11.00.5
Locomotion velocity, hab. session 10.71.01.7-1.00.61.3-0.91.10.40.81.1-1.1-1.1-0.90.91.3-1.1-1.0-1.01.30.6
Time in familiar zone, hab. session 20.40.41.20.9-0.8-0.80.8-0.90.0-0.6-0.60.60.50.6-0.6-0.1-0.2-0.30.10.11.1
Time in novel zone, hab. session 20.20.20.8-0.60.60.6-0.40.6-0.10.40.4-0.4-0.3-0.40.40.00.10.2-0.0-0.2-0.9
Total zone transitions, hab. session 20.30.31.2-0.4-0.20.8-0.20.40.00.10.5-0.4-0.5-1.01.00.7-0.6-0.5-1.10.40.1
Total locomotion distance, hab. session 20.40.51.5-0.6-0.11.0-0.30.50.10.30.7-0.6-0.7-1.11.10.9-0.9-0.8-1.20.70.3
Locomotion velocity, hab. session 20.50.71.9-0.7-0.01.1-0.60.60.20.40.8-0.8-0.8-1.21.20.9-0.9-0.8-1.40.90.3
Novel to familiar place preference ratio0.30.30.60.6-0.2-0.60.6-0.5-0.5-0.5-0.60.60.40.8-0.8-0.30.20.40.7-0.30.3
Novelty place preference0.70.71.11.0-0.7-1.01.0-1.0-0.8-0.9-1.01.00.80.9-0.9-0.70.50.60.7-0.60.4
Time in novel zone, NPP test0.80.81.51.2-0.8-1.11.2-1.1-0.9-1.0-1.11.10.91.1-1.1-0.60.40.60.8-0.50.5
Total zone transitions, NPP test1.31.96.6-0.8-0.41.6-0.90.90.30.51.1-1.1-1.1-2.32.31.3-1.0-1.1-2.61.21.4
Total locomotion distance, NPP test0.91.23.5-0.7-0.21.2-0.80.80.20.50.9-0.9-1.0-1.61.61.2-1.1-1.0-1.91.31.3
Locomotion velocity, NPP test0.81.13.3-0.7-0.11.3-0.80.80.20.50.9-0.9-0.9-1.71.71.1-0.8-0.8-1.81.10.9
Intraocular pressure0.10.10.80.3-0.2-0.10.3-0.1-0.3-0.2-0.30.2-0.10.3-0.30.5-0.3-0.3-0.10.50.9
Delta distance traveled before/after self-admin3.53.85.41.9-1.4-2.02.3-1.8-2.1-2.1-2.12.12.11.3-1.3-2.02.12.01.6-2.3-2.0
Delta ambulatory time before/after self-admin2.62.94.41.8-1.3-1.82.1-1.6-1.8-1.9-1.91.91.81.4-1.4-1.61.61.51.4-1.9-1.3
Parametrial fat weight0.81.53.61.7-1.9-1.41.5-1.6-1.8-1.7-1.41.51.20.5-0.5-0.70.70.80.0-0.7-0.2
Pavlov. Cond. lever latency0.00.00.3-0.10.00.40.20.2-0.6-0.2-0.20.1-0.0-0.30.30.20.10.1-0.1-0.1-0.0
Pavlov. Cond. magazine entry latency0.10.10.50.4-0.7-0.30.3-0.5-0.1-0.3-0.20.20.2-0.40.4-0.1-0.1-0.1-0.6-0.00.6
Pavlov. Cond. change in total contacts0.20.20.70.2-0.8-0.10.1-0.50.1-0.20.00.10.1-0.70.7-0.30.10.0-0.8-0.30.5
Pavlov. Cond. index score0.10.10.60.3-0.7-0.20.0-0.50.1-0.20.00.10.1-0.60.6-0.2-0.1-0.2-0.8-0.00.4
Pavlov. Cond. latency score0.10.10.50.4-0.7-0.40.2-0.60.0-0.3-0.10.20.3-0.40.4-0.30.00.0-0.5-0.20.2
Pavlov. Cond. lever contacts0.10.10.40.3-0.1-0.6-0.0-0.50.60.10.00.10.10.5-0.5-0.2-0.2-0.30.3-0.00.3
Pavlov. Cond. magazine entry number0.30.31.1-0.71.10.5-0.60.90.60.80.5-0.6-0.50.3-0.30.4-0.3-0.20.50.4-0.1
Pavlov. Cond. intertrial magazine entries0.60.71.2-0.90.61.1-0.81.00.70.70.9-0.9-0.8-0.90.90.9-0.7-1.0-0.90.80.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.80.2-0.6-0.1-0.1-0.40.2-0.10.2-0.0-0.0-0.60.60.0-0.3-0.3-0.90.20.7
Pavlov. Cond. response bias0.10.20.60.6-0.7-0.60.2-0.7-0.0-0.4-0.20.30.4-0.20.2-0.40.10.0-0.3-0.20.4
Pavlov. Cond. lever latency2.73.76.91.8-1.4-1.81.7-1.8-1.9-1.8-2.01.92.20.8-0.8-2.62.62.61.3-2.3-2.1
Pavlov. Cond. magazine entry latency0.20.20.50.7-0.6-0.30.7-0.6-0.6-0.6-0.50.50.30.1-0.10.1-0.1-0.0-0.20.20.5
Pavlov. Cond. change in total contacts0.91.23.2-0.70.90.6-0.80.81.00.91.0-0.9-1.20.3-0.31.7-1.8-1.7-0.21.71.4
Pavlov. Cond. index score0.60.72.0-0.50.50.7-0.40.60.60.50.7-0.7-0.9-0.10.11.4-1.4-1.3-0.61.41.1
Pavlov. Cond. latency score0.30.41.4-0.20.20.4-0.20.30.30.20.4-0.4-0.6-0.10.11.1-1.1-1.1-0.61.21.2
Pavlov. Cond. lever contacts3.14.26.8-2.01.42.2-1.92.01.71.82.2-2.1-2.3-1.41.42.6-2.6-2.5-1.82.41.9
Pavlov. Cond. magazine entry number0.20.30.6-0.80.80.5-0.80.70.60.70.6-0.6-0.4-0.20.2-0.00.00.00.2-0.1-0.5
Pavlov. Cond. intertrial magazine entries0.70.91.5-1.20.91.1-1.11.21.01.11.0-1.1-1.0-0.70.70.9-0.7-0.9-0.60.80.1
Pavlov. Cond. lever-magazine prob. diff.0.50.61.8-0.40.40.6-0.40.50.50.50.6-0.6-0.9-0.20.21.3-1.3-1.3-0.71.31.1
Pavlov. Cond. response bias2.02.75.3-1.61.21.7-1.41.61.41.41.7-1.7-1.9-0.80.82.3-2.2-2.2-1.22.11.5
Time in closed arm before self-admin0.20.21.00.3-1.0-0.30.1-0.50.1-0.20.00.10.2-0.40.4-0.20.1-0.0-0.5-0.40.9
Time in closed arm after self-admin0.30.31.3-0.50.9-0.1-0.40.21.10.70.3-0.3-0.30.7-0.70.1-0.2-0.20.70.40.3
Time in open arm before self-admin0.70.82.3-0.80.41.1-0.80.60.50.60.7-0.7-0.7-1.51.50.6-0.5-0.4-1.51.00.5
Time in open arm after self-admin0.10.10.30.5-0.4-0.40.2-0.4-0.5-0.4-0.30.30.20.3-0.30.1-0.3-0.20.00.10.1
Bone: periosteal estimation0.50.93.41.0-1.4-0.21.4-0.9-1.8-1.5-1.11.00.8-0.60.6-0.30.50.6-0.8-0.5-0.5
Bone: periosteal perimeter0.81.35.00.7-1.80.50.9-0.5-1.8-1.3-0.50.50.3-2.02.00.10.20.3-2.2-0.00.2
Bone: post-yield work0.30.41.0-0.30.7-0.0-0.30.30.80.60.3-0.3-0.60.9-0.90.7-1.0-0.90.50.90.8
Progressive ratio test 1 active lever presses1.11.22.81.3-0.4-1.51.1-1.1-0.7-0.9-1.21.21.01.7-1.7-0.90.70.61.4-0.5-0.3
Progressive ratio test 1 breakpoint0.70.72.70.8-0.1-1.20.9-0.8-0.2-0.5-0.80.80.61.6-1.6-0.50.20.11.3-0.2-0.1
Progressive ratio test 1 inactive lever presses0.30.43.50.4-0.5-0.30.1-0.50.4-0.1-0.10.1-0.1-0.10.10.4-0.7-0.8-0.50.61.9
Progressive ratio test 2 active lever presses3.94.28.32.4-1.2-2.82.2-2.1-1.4-1.8-2.32.32.02.9-2.9-1.71.61.52.5-1.3-0.8
Progressive ratio test 2 breakpoint3.74.19.62.3-1.1-2.82.1-2.0-1.3-1.7-2.22.21.93.1-3.1-1.61.41.32.7-1.1-0.7
Progressive ratio test 2 inactive lever presses1.82.14.61.9-1.5-2.11.6-2.0-0.6-1.4-1.61.61.41.6-1.6-1.10.60.51.1-1.00.9
Incentive Sensitization - Responses2.52.55.02.0-1.1-2.21.7-1.7-1.1-1.4-1.81.81.62.2-2.2-1.31.11.11.7-0.6-0.2
Incentive Sensitization - Breakpoint2.22.24.31.9-1.1-2.11.7-1.7-1.0-1.4-1.71.71.52.0-2.0-1.21.01.01.6-0.6-0.1
Sum of active levers in priming session hrs 5-60.60.61.4-0.50.30.8-0.50.40.60.60.7-0.7-0.7-1.11.10.7-0.6-0.8-1.20.91.1
Progressive ratio0.40.51.5-1.01.21.0-0.51.10.60.70.4-0.6-0.7-0.10.10.7-0.5-0.40.00.6-0.1
Food seeking constrained by brief footshock0.50.61.3-0.81.10.80.00.80.80.70.5-0.6-0.80.0-0.01.1-1.0-1.0-0.11.01.0
Seeking ratio, punishment vs. effort0.10.10.60.5-0.5-0.60.3-0.60.1-0.2-0.10.20.10.3-0.30.0-0.3-0.3-0.00.20.8
Retroperitoneal fat weight4.414.326.04.8-5.1-4.24.6-4.9-4.1-4.7-4.24.44.11.4-1.4-3.63.23.11.0-4.0-1.1
Reaction time number correct2.23.16.12.0-1.9-1.52.5-1.7-2.1-2.1-2.22.11.90.6-0.6-1.71.82.00.7-1.9-1.0
Reaction time mean minus median0.40.61.10.7-0.1-0.90.7-0.5-0.8-0.7-0.80.80.80.8-0.8-0.70.70.60.9-0.6-1.0
Reaction time mean minus median AUC1.31.72.31.5-0.9-1.51.2-1.2-1.4-1.3-1.41.41.51.0-1.0-1.41.51.31.1-1.2-1.5
Reaction time num false alarms1.01.42.3-1.10.51.1-1.40.91.11.11.3-1.2-1.3-0.90.91.3-1.4-1.3-1.21.51.4
Reaction time num false alarms AUC1.62.12.9-1.61.01.6-1.71.41.21.41.7-1.6-1.7-1.11.11.6-1.5-1.5-1.31.71.1
Reaction time trials correct on left2.23.16.12.0-1.9-1.52.5-1.7-2.1-2.1-2.22.11.90.6-0.6-1.71.82.00.7-1.9-1.0
Reaction time trials on left2.23.26.32.0-1.8-1.52.5-1.7-2.1-2.1-2.32.12.00.7-0.7-1.71.82.00.8-1.9-1.0
Reaction time mean0.60.82.40.7-0.3-1.00.6-0.6-0.8-0.7-0.80.80.90.8-0.8-1.11.00.91.0-1.0-1.5
Reaction time mean AUC0.50.71.80.6-0.0-1.00.3-0.5-0.4-0.4-0.60.60.71.1-1.1-0.90.90.71.3-0.8-1.4
Median of all reaction times0.60.92.40.7-0.5-0.90.6-0.7-0.8-0.7-0.80.81.00.6-0.6-1.21.21.10.9-1.2-1.6
Reaction time omissions1.62.25.61.3-0.1-1.91.4-1.2-0.4-0.9-1.61.51.42.4-2.4-1.41.31.12.4-1.1-1.1
Reaction time false alarm rate3.34.77.5-2.31.92.0-2.72.02.32.42.6-2.4-2.5-1.01.02.3-2.4-2.5-1.32.51.8
Reaction time premature initiation rate1.52.09.7-1.0-0.61.9-0.70.8-0.50.10.8-0.9-0.8-3.13.10.5-0.0-0.1-2.80.20.2
Reaction time premature initiations1.31.87.20.1-1.61.00.7-0.1-1.7-1.1-0.40.30.4-2.72.7-0.41.01.1-2.3-0.8-0.5
Std. dev. reaction times0.91.22.21.1-0.4-1.41.0-0.9-1.0-1.0-1.11.21.11.4-1.4-1.01.10.81.4-0.8-1.5
Reaction time trials completed2.23.26.32.0-1.8-1.52.5-1.7-2.1-2.1-2.32.12.00.7-0.7-1.71.82.00.8-1.9-1.0
Reaction time trials AUC2.23.16.32.0-1.9-1.52.5-1.7-2.1-2.1-2.32.12.00.7-0.7-1.61.81.90.7-1.8-1.0
Run reversals in cocaine runway, females2.42.34.91.2-0.9-1.21.8-0.8-1.7-1.5-1.71.61.61.1-1.1-1.51.91.71.5-1.7-2.2
Run reversals in cocaine runway, males0.20.21.0-0.60.40.5-1.00.50.80.60.4-0.5-0.4-0.40.40.2-0.3-0.3-0.30.20.3
Latency to leave start box in cocaine runway0.30.30.8-0.70.80.6-0.90.80.40.70.7-0.7-0.6-0.40.40.5-0.4-0.2-0.20.6-0.0
Latency to leave start box in cocaine runway, F0.80.91.9-1.21.31.2-1.11.40.51.11.0-1.1-0.9-1.01.00.6-0.3-0.1-0.50.5-0.4
Latency to leave start box in cocaine runway, M0.20.20.70.4-0.1-0.60.3-0.2-0.3-0.2-0.40.40.20.9-0.9-0.00.00.00.50.40.1
Std. dev. time between licks in bursts0.40.41.60.10.4-0.5-0.0-0.10.60.40.1-0.0-0.31.3-1.30.5-0.8-0.70.80.70.9
Total sessions with >9 infusions2.32.54.82.1-1.6-1.81.6-1.9-2.2-1.9-1.71.81.60.7-0.7-1.51.71.70.6-1.1-1.0
Short access day 1 total inactive lever presses0.80.92.31.5-1.2-1.11.1-1.4-1.1-1.3-1.11.11.10.0-0.0-0.80.70.7-0.2-0.20.3
Short access day 10 total inactive lever presses0.50.62.30.3-1.20.30.3-0.5-0.3-0.6-0.30.20.2-1.41.40.0-0.2-0.2-1.5-0.11.3
Short access day 1 total infusions2.62.85.32.3-1.8-1.91.8-2.1-1.9-2.0-1.91.91.80.6-0.6-1.71.91.70.4-1.1-0.5
Short access day 10 total infusions0.20.20.90.6-0.4-0.70.3-0.6-0.1-0.3-0.40.40.20.8-0.80.0-0.2-0.20.40.11.0
Short access total infusions1.01.12.41.4-0.7-1.61.1-1.2-0.8-1.0-1.21.21.01.4-1.4-0.70.80.61.1-0.2-0.2
Short access day 1 locomotion3.03.25.32.3-2.0-2.31.8-2.2-2.0-2.1-2.02.11.91.3-1.3-1.81.61.81.0-1.3-0.8
Short access day 10 total locomotion1.72.05.31.5-2.3-1.31.3-1.8-1.4-1.6-1.11.31.4-0.60.6-1.71.21.3-0.4-2.1-0.8
Short access total locomotion1.21.32.31.1-1.1-1.41.1-1.4-1.0-1.2-1.01.21.20.7-0.7-1.30.91.10.8-1.5-1.2
One hour access (0.3 mA shock)4.65.39.43.0-2.1-3.12.7-2.7-2.2-2.5-2.82.72.42.6-2.6-1.81.51.61.9-1.0-0.4
Compulsive drug intake0.20.20.6-0.50.70.8-0.30.70.00.30.2-0.3-0.4-0.30.30.6-0.2-0.3-0.30.7-0.0
One hour access (shock baseline)2.42.85.72.1-1.7-2.41.9-2.1-1.4-1.7-1.81.91.71.8-1.8-1.41.01.31.3-1.0-0.4
Social response proportion9.09.812.93.5-3.3-3.13.4-3.4-3.6-3.6-3.43.43.61.0-1.0-3.53.53.41.3-3.4-2.2
Social responses2.83.66.32.0-1.9-1.72.4-1.7-2.5-2.3-2.22.22.00.9-0.9-1.72.01.81.0-2.2-1.8
Social time4.55.911.12.2-1.7-2.12.9-2.2-2.8-2.6-2.62.62.61.4-1.4-2.52.62.61.8-2.7-3.3
Soleus weight1.85.211.52.6-3.4-1.52.4-2.6-3.2-3.0-2.22.32.3-1.11.1-2.22.32.3-1.0-2.3-1.4
Bone: stiffness0.00.10.2-0.20.10.40.10.3-0.5-0.1-0.0-0.0-0.1-0.20.20.2-0.00.2-0.10.0-0.3
Tibialis anterior weight0.30.94.3-0.40.00.6-0.70.31.10.70.8-0.8-0.9-0.70.71.0-1.2-1.3-1.11.12.1
Time to tail flick, vehicle, before self-admin0.70.72.40.9-1.2-0.51.0-0.9-1.6-1.2-0.80.90.7-0.20.2-0.60.70.7-0.3-0.5-0.7
Time to tail flick, vehicle, after self-admin0.10.10.80.2-0.4-0.00.20.0-0.7-0.3-0.20.10.3-0.20.2-0.30.60.4-0.1-0.2-0.9
Time to tail flick, test, before self-admin0.10.10.40.1-0.40.10.0-0.1-0.6-0.20.00.10.1-0.40.4-0.30.40.5-0.3-0.6-0.6
Time to tail flick, test, after self-admin0.00.00.10.3-0.3-0.0-0.1-0.1-0.4-0.2-0.10.10.1-0.20.20.10.1-0.0-0.30.30.2
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.30.60.0-0.30.50.40.40.1-0.2-0.10.6-0.60.10.1-0.00.70.1-0.5
Delta time to tail flick, test, before/after SA0.10.10.20.4-0.3-0.10.1-0.1-0.3-0.3-0.30.20.2-0.10.10.10.2-0.1-0.20.40.2
Tibia length0.72.17.30.0-1.51.20.90.1-1.9-1.2-0.50.40.5-2.72.7-0.61.31.4-2.0-1.5-1.5
Ambulatory time before self-admin0.60.62.9-0.60.01.0-0.90.50.40.50.7-0.7-0.3-1.71.70.00.0-0.1-1.40.40.2
Ambulatory time after self-admin2.93.25.51.6-2.4-1.01.6-1.7-2.1-2.0-1.61.62.0-1.41.4-2.22.32.1-0.9-2.0-1.3
Bone: tissue strength0.60.62.90.20.6-0.90.1-0.30.60.2-0.30.30.21.7-1.7-0.2-0.1-0.21.50.00.1
Total heroin consumption0.30.31.3-0.30.2-0.00.2-0.00.80.30.2-0.1-0.30.6-0.60.6-1.1-1.10.20.51.0
Bone: trabecular number1.21.83.31.8-1.3-1.81.6-1.8-1.0-1.4-1.61.61.51.3-1.3-1.21.01.00.9-0.90.0
Bone: trabecular spacing1.52.02.7-1.61.01.5-1.61.41.51.41.6-1.6-1.6-1.11.11.5-1.6-1.6-1.11.31.1
Bone: trabecular thickness2.32.88.72.1-2.9-1.21.9-2.2-2.1-2.2-1.61.71.6-1.01.0-1.21.01.1-1.5-0.90.7
Bone: trabecular tissue density0.30.41.6-0.4-0.10.5-0.70.20.30.30.7-0.6-0.4-1.21.20.2-0.4-0.3-1.20.30.1
Water consumed over 24 hours1.41.63.11.5-1.7-0.91.2-1.4-1.8-1.6-1.31.31.4-0.50.5-1.41.51.6-0.4-1.1-0.8
Number of responses in last shaping day0.30.31.10.4-0.2-0.40.5-0.2-0.8-0.5-0.50.50.50.5-0.5-0.50.70.80.6-0.5-1.1