Hub : Genes

Tasp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_039105024.1 0.03 0.02 1.1e-03 0.02 0.02 0.02 0.01 3.5e-03 2.0e-03 1.6e-03 1.8e-02
2 Adipose alternative TSS XM_039105024.1 0.03 0.02 4.6e-03 0.01 0.01 0.01 0.01 4.3e-02 1.2e-02 7.6e-03 4.7e-02
3 Adipose alternative TSS XM_039105025.1 0.06 0.04 6.0e-06 0.03 0.05 0.04 0.05 3.6e-04 1.8e-06 1.5e-05 3.5e-06
4 Adipose alternative TSS XM_039105025.1 0.07 0.04 1.3e-06 0.03 0.06 0.06 0.05 2.4e-04 5.2e-07 9.7e-07 1.3e-06
5 Adipose alternative TSS XM_039105026.1 0.03 0.02 5.2e-03 0.01 0.01 0 0 3.6e-02 1.6e-02 1.6e-01 7.9e-02
6 Adipose alternative TSS XM_039105026.1 0.04 0.03 7.3e-04 0.01 0.02 0.02 0.01 9.4e-03 1.3e-03 4.8e-03 7.5e-03
7 NAcc intron excision ratio chr3_127385117_127399392 0.04 0.03 1.4e-05 0.03 0.04 0.03 0.04 9.7e-05 1.2e-05 3.8e-04 4.9e-05
8 PL gene expression Tasp1 0.03 0.02 2.7e-03 0.01 0.01 0.01 0.01 2.8e-02 1.0e-02 5.7e-02 3.4e-02
9 PL isoform ratio XM_039105026.1 0.04 0.03 4.1e-05 0.05 0.04 0.03 0.04 8.5e-06 9.3e-06 2.3e-04 1.7e-05
10 NAcc isoform ratio XM_039105026.1 0.03 0.02 5.7e-04 0.03 0.02 0.03 0.03 1.2e-04 7.1e-04 8.0e-05 2.5e-04
11 PL isoform ratio XM_039105027.1 0.05 0.03 6.7e-05 0.05 0.04 0.04 0.04 8.5e-06 3.1e-05 4.8e-05 4.1e-05
12 BLA mRNA stability Tasp1 0.08 0.05 4.0e-04 0.07 0.06 0.03 0.06 1.5e-04 4.0e-04 8.1e-03 2.9e-04
13 IL mRNA stability Tasp1 0.11 0.07 7.4e-03 0.04 0.05 -0 0.03 3.4e-02 2.8e-02 4.0e-01 7.8e-02
14 LHb mRNA stability Tasp1 0.18 0.1 5.7e-04 0.12 0.09 0.08 0.1 1.0e-03 4.0e-03 7.2e-03 2.5e-03
15 NAcc isoform ratio XM_039105027.1 0.04 0.03 3.7e-06 0.05 0.05 0.04 0.04 1.6e-06 3.7e-06 5.9e-05 1.8e-05
16 OFC mRNA stability Tasp1 0.21 0.11 5.2e-04 0.06 0.07 0.1 0.08 1.7e-02 7.8e-03 2.5e-03 5.6e-03
17 PL intron excision ratio chr3_127385117_127399392 0.02 0.01 4.8e-03 0.03 0.02 0.02 0.02 9.1e-04 1.5e-03 2.9e-03 1.8e-03
18 Brain isoform ratio XM_039105026.1 0.04 0.03 3.7e-03 0.03 0.02 0.01 0.02 1.1e-03 5.2e-03 1.6e-02 5.8e-03
19 PL mRNA stability Tasp1 0.05 0.03 3.9e-06 0.04 0.03 0.04 0.04 3.6e-05 6.7e-04 8.4e-05 4.4e-05
20 Brain mRNA stability Tasp1 0.17 0.12 4.2e-11 0.13 0.12 0.11 0.13 2.1e-12 2.1e-11 1.1e-10 1.9e-12
21 Adipose isoform ratio XM_017591759.2 0.03 0.02 1.0e-03 0.01 0.01 0 0.01 6.7e-03 1.8e-02 9.3e-02 3.5e-02
22 NAcc intron excision ratio chr3_127385117_127390780 0.04 0.03 5.8e-03 -0 0 0 -0 4.3e-01 9.9e-02 1.2e-01 4.3e-01
23 Brain isoform ratio XM_039105027.1 0.06 0.04 1.9e-06 0.07 0.06 0.07 0.07 6.2e-07 1.2e-06 5.7e-07 9.3e-07
24 Brain intron excision ratio chr3_127385117_127399392 0.05 0.03 1.0e-03 0.02 0.03 0.03 0.03 3.0e-03 1.1e-03 9.0e-04 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.81.42.90.40.40.80.8-0.9-0.8-0.8-0.91.61.30.11.6-1.41.5-1.51.61.6-0.11.6-1.7-1.7-0.5-1.21.1
Area under the delay curve0.50.51.1-0.9-1.0-1.0-1.00.80.80.71.0-0.4-0.61.1-0.50.4-0.60.5-0.4-0.6-1.0-0.60.50.5-0.80.7-0.6
BMI with tail5.016.221.94.64.54.54.5-4.7-4.7-4.7-3.84.24.3-3.04.2-4.44.2-4.24.24.02.83.8-3.9-3.83.8-2.42.1
BMI without tail4.49.014.83.53.33.53.5-3.6-3.7-3.8-2.52.93.1-2.12.9-3.33.2-3.23.03.22.02.6-2.6-2.63.8-0.90.7
Body weight7.732.444.86.76.66.66.6-6.6-6.6-6.4-5.85.75.9-5.05.8-5.85.6-5.75.65.54.55.2-5.1-5.15.3-3.93.5
Weight adjusted by age0.50.61.10.80.80.80.8-0.8-0.7-0.6-1.00.70.8-1.00.8-0.70.9-0.80.70.80.70.8-0.7-0.60.1-0.80.9
Bone surface0.40.72.3-0.5-0.6-0.1-0.1-0.2-0.3-0.40.40.90.61.50.9-1.20.9-0.91.01.1-1.51.0-1.0-1.0-0.40.4-0.6
Bone volume0.50.82.00.20.10.50.5-0.7-0.7-0.8-0.31.10.90.61.2-1.41.2-1.21.21.4-0.61.3-1.4-1.4-0.1-0.40.2
Breakpoint value in progressive ratio session1.21.32.21.31.21.21.2-1.1-1.1-1.0-1.31.11.2-1.51.1-0.91.0-1.01.11.21.31.1-1.0-1.00.6-1.11.2
Number of licking bursts0.40.41.50.91.00.70.7-0.6-0.5-0.4-0.90.10.3-1.00.3-0.20.2-0.20.20.11.20.3-0.1-0.10.3-1.11.1
Context. condit. distance diff. score0.10.10.30.00.10.20.2-0.1-0.1-0.1-0.40.20.5-0.40.1-0.10.5-0.50.40.50.40.5-0.5-0.5-0.2-0.40.5
Locomotion velocity, session 10.70.71.5-1.0-1.0-0.9-0.90.90.80.80.9-1.2-0.90.8-1.10.7-0.80.8-0.9-0.7-1.0-0.40.50.5-0.60.8-0.9
Locomotion distance, session 13.24.28.3-2.7-2.8-2.4-2.42.12.01.72.7-1.8-1.72.9-1.71.2-1.41.4-1.3-1.3-2.9-1.21.31.3-1.32.6-2.6
Locomotion velocity, session 22.22.64.5-2.1-2.0-1.9-1.91.92.02.01.5-1.7-1.61.5-1.61.6-1.31.3-1.4-1.3-1.6-1.11.21.2-2.10.8-0.7
Locomotion distance, session 23.95.59.1-3.0-3.0-2.8-2.82.72.62.42.7-2.2-2.12.8-1.91.9-1.91.9-1.8-1.9-2.6-1.92.02.0-2.32.0-1.9
Locomotion velocity, session 30.40.51.4-0.7-0.8-0.8-0.80.70.60.50.9-0.6-0.71.0-0.30.4-0.50.5-0.4-0.6-1.2-0.50.50.5-0.31.0-1.0
Locomotion distance, session 30.00.00.10.10.10.00.0-0.1-0.0-0.1-0.00.20.2-0.00.3-0.10.1-0.10.20.1-0.2-0.00.00.1-0.1-0.10.0
Stereotopy head waving bouts, day 30.50.61.10.40.40.60.6-0.8-0.8-0.9-0.30.90.80.30.9-1.11.0-1.01.01.0-0.01.0-1.0-1.00.60.1-0.1
Stereotopy head waving duration, day 30.20.20.50.30.20.40.4-0.5-0.5-0.6-0.10.40.50.10.5-0.60.6-0.60.60.60.10.7-0.7-0.70.60.2-0.2
Locomotion velocity, session 70.60.61.5-0.8-0.6-0.8-0.80.91.11.10.2-1.1-0.60.0-0.81.2-0.70.7-0.8-0.80.1-0.80.90.9-1.2-0.40.4
Locomotion distance, session 70.10.20.40.40.40.40.4-0.4-0.4-0.3-0.50.40.5-0.30.5-0.30.4-0.40.40.40.50.3-0.3-0.30.0-0.60.7
Stereotopy head waving bouts, day 70.10.10.50.30.20.20.2-0.3-0.3-0.40.10.10.1-0.20.4-0.30.2-0.20.20.2-0.10.4-0.4-0.40.70.4-0.5
Stereotopy head waving duration, day 70.20.21.2-0.0-0.2-0.1-0.1-0.1-0.2-0.40.50.1-0.00.60.4-0.50.3-0.30.30.3-0.80.4-0.4-0.40.61.0-1.1
Locomotion velocity, session 81.11.42.4-1.6-1.5-1.4-1.41.41.51.41.0-1.5-1.00.8-1.11.3-1.01.0-1.0-1.0-1.0-0.80.80.8-1.40.6-0.6
Locomotion distance, session 81.11.73.5-1.9-1.8-1.6-1.61.61.61.51.4-1.3-1.01.4-1.21.2-0.80.8-0.9-0.9-1.4-0.80.80.8-1.61.0-0.9
Degree of sensitization distance0.00.00.3-0.3-0.3-0.1-0.1-0.0-0.0-0.00.10.10.20.50.1-0.20.3-0.30.30.3-0.10.3-0.3-0.3-0.10.1-0.0
Degree of sensitization stereotypy0.10.10.20.30.20.20.2-0.2-0.2-0.2-0.20.20.2-0.40.4-0.10.3-0.30.20.30.10.4-0.4-0.50.30.0-0.1
Conditioned locomotion2.02.43.31.71.71.81.8-1.8-1.8-1.8-1.61.51.6-1.31.6-1.61.6-1.61.61.51.31.4-1.3-1.21.5-1.01.0
Cocaine response after cond. corrected0.40.42.1-0.4-0.3-0.5-0.50.70.91.0-0.2-0.5-0.4-0.1-0.60.9-0.50.5-0.6-0.40.6-0.20.40.4-1.4-1.01.1
Cocaine response after cond. not corrected0.40.52.1-0.7-0.6-0.7-0.70.81.01.10.1-0.7-0.50.3-0.70.9-0.60.6-0.6-0.40.2-0.30.50.5-1.4-0.60.8
Cocaine response before conditioning0.20.31.4-0.7-0.8-0.6-0.60.40.30.30.8-0.3-0.31.2-0.2-0.1-0.20.2-0.1-0.0-1.1-0.20.10.1-0.30.7-0.8
Saline control response0.00.10.10.20.20.30.3-0.3-0.3-0.3-0.10.30.2-0.20.3-0.40.2-0.20.20.2-0.1-0.1-0.0-0.00.3-0.1-0.0
Bone: connectivity density0.91.53.2-0.6-0.6-0.0-0.0-0.3-0.2-0.3-0.21.61.21.21.6-1.31.6-1.61.71.8-1.11.6-1.7-1.7-1.5-0.80.7
Bone: cortical apparent density1.21.64.72.02.01.71.7-1.5-1.5-1.3-1.50.30.8-2.20.4-0.60.4-0.40.30.32.00.4-0.3-0.32.0-0.90.9
Bone: cortical area5.68.414.93.73.83.53.5-3.2-3.1-2.9-3.62.22.8-3.92.3-2.12.3-2.32.12.23.72.1-2.1-2.12.6-2.92.8
Bone: cortical porosity1.81.94.10.81.00.90.9-1.0-0.8-0.6-1.32.01.5-0.21.9-1.21.6-1.61.71.70.31.8-1.8-1.8-0.8-1.91.7
Bone: cortical porosity2.62.96.31.31.51.41.4-1.3-1.1-0.8-2.02.21.8-1.02.1-1.31.8-1.81.91.91.11.9-1.9-1.9-0.7-2.52.3
Bone: cortical thickness11.318.632.65.45.55.25.2-4.7-4.5-4.1-5.43.54.2-5.73.4-3.13.5-3.53.23.35.43.3-3.4-3.43.5-4.54.4
Bone: cortical thickness4.45.19.42.52.72.62.6-2.2-2.0-1.8-3.01.82.3-2.91.9-1.41.9-1.91.81.93.11.9-1.9-1.91.1-2.82.9
Bone: cortical tissue density0.91.24.01.81.81.51.5-1.3-1.3-1.2-1.30.20.6-2.00.2-0.40.3-0.30.10.21.80.2-0.2-0.21.9-0.70.6
Condit. Reinf. active minus inactive responses1.01.22.40.90.81.01.0-1.1-1.1-1.2-0.81.51.20.11.5-1.41.4-1.41.41.30.31.1-1.1-1.10.5-0.60.5
Condit. Reinf. active-inactive response ratio0.80.81.80.60.70.70.7-0.7-0.6-0.5-1.01.11.1-0.31.2-0.81.1-1.11.11.00.80.9-0.9-0.9-0.4-1.31.3
Condit. Reinf. active responses0.10.10.20.20.20.20.2-0.3-0.3-0.40.10.3-0.00.30.4-0.40.1-0.10.10.0-0.3-0.00.10.10.50.3-0.4
Condit. Reinf. inactive responses1.01.23.5-0.7-0.9-0.8-0.80.70.60.51.3-1.0-1.40.6-1.00.7-1.31.3-1.2-1.3-1.3-1.11.11.10.61.7-1.9
Incentive salience index mean0.20.31.6-0.5-0.6-0.5-0.50.30.20.10.80.0-0.31.20.1-0.2-0.00.00.0-0.1-1.1-0.30.30.3-0.10.8-0.9
Condit. Reinf. lever presses2.02.64.5-1.6-1.7-1.7-1.71.51.41.22.0-1.5-1.61.7-1.41.1-1.51.5-1.5-1.6-2.0-1.71.71.8-0.52.1-2.1
Condit. Reinf. active minus inactive responses0.30.30.6-0.6-0.7-0.6-0.60.60.50.40.7-0.6-0.60.3-0.70.5-0.60.6-0.6-0.6-0.2-0.60.50.5-0.00.8-0.7
Condit. Reinf. active-inactive response ratio0.30.30.5-0.7-0.7-0.7-0.70.70.70.60.6-0.7-0.60.3-0.50.6-0.60.6-0.5-0.6-0.3-0.60.50.5-0.40.5-0.4
Condit. Reinf. active responses0.20.31.5-0.5-0.6-0.4-0.40.40.20.10.8-0.6-0.40.2-0.70.3-0.40.4-0.6-0.5-0.2-0.60.40.40.61.2-1.1
Condit. Reinf. inactive responses0.20.31.90.1-0.00.10.1-0.1-0.3-0.50.5-0.2-0.20.1-0.4-0.1-0.30.3-0.4-0.2-0.2-0.50.30.31.41.3-1.2
Condit. Reinf. lever presses1.21.75.7-1.3-1.5-1.4-1.41.00.70.52.1-0.9-1.12.2-1.00.2-0.90.8-0.8-0.9-1.6-0.90.90.90.22.4-2.2
Condit. Reinf. lever reinforcers received0.50.72.4-0.8-0.9-0.8-0.80.70.50.31.1-0.9-0.80.6-1.00.5-0.80.8-0.9-0.8-0.5-0.90.70.70.41.5-1.4
Conditioned reinforcement - actives1.81.86.7-1.7-1.6-1.6-1.61.61.81.91.0-0.9-1.11.5-0.91.3-0.90.9-0.9-1.1-1.0-1.01.21.2-2.6-0.30.4
Conditioned reinforcement - inactives0.80.91.8-1.0-1.0-1.0-1.00.90.90.81.1-0.8-0.81.2-0.70.8-0.80.9-0.7-0.9-0.7-1.31.31.4-0.50.9-0.8
Conditioned locomotion2.22.76.5-2.1-1.9-1.9-1.92.02.12.21.3-1.4-1.51.6-1.41.8-1.51.5-1.4-1.4-0.9-1.51.51.5-2.50.10.1
Patch foraging indifference point 0 sec1.32.24.9-1.3-1.5-1.5-1.51.31.10.91.9-1.2-1.41.7-1.30.9-1.31.3-1.2-1.3-1.8-1.81.51.6-0.12.2-2.2
Patch foraging indifference point AUC6.67.613.0-2.1-2.1-2.5-2.52.72.62.62.3-3.6-3.20.8-3.43.2-3.43.4-3.4-3.3-0.9-3.43.43.4-1.01.9-1.7
Delay disc. indifference point, 0s delay0.00.10.3-0.3-0.3-0.3-0.30.20.30.30.1-0.0-0.2-0.1-0.20.1-0.10.1-0.10.0-0.10.2-0.2-0.3-0.5-0.10.2
Delay disc. indifference point, 16s delay1.81.82.8-1.6-1.7-1.6-1.61.51.51.51.5-1.0-1.31.5-1.11.1-1.21.1-1.1-1.3-1.6-1.31.21.3-1.41.0-0.9
Delay disc. indifference point, 2s delay1.41.64.7-1.6-1.7-1.6-1.61.31.31.11.7-0.8-1.01.9-0.70.6-0.80.9-0.6-0.8-2.2-0.80.80.8-1.21.4-1.5
Delay disc. indifference point, 24s delay0.20.20.8-0.4-0.5-0.4-0.40.20.10.00.7-0.3-0.30.7-0.2-0.0-0.30.2-0.2-0.4-0.4-0.40.30.30.30.9-0.8
Delay disc. indifference point, 4s delay0.10.10.7-0.6-0.7-0.5-0.50.50.50.50.40.0-0.10.40.00.2-0.10.10.00.0-0.5-0.10.10.1-0.90.00.0
Delay disc. indifference point, 8s delay0.00.00.2-0.1-0.2-0.2-0.20.10.10.10.30.0-0.00.40.1-0.1-0.00.00.10.1-0.10.2-0.3-0.4-0.10.3-0.1
Indifference point function ln k4.66.411.41.91.92.32.3-2.5-2.5-2.6-2.03.43.0-0.73.1-3.03.3-3.33.23.10.92.8-2.9-2.91.1-1.51.4
Indifference point function log k4.66.411.41.91.92.32.3-2.5-2.5-2.6-2.03.43.0-0.73.1-3.03.3-3.33.23.10.92.8-2.9-2.91.1-1.51.4
Patch foraging total patch changes 0 sec1.83.06.2-1.5-1.6-1.7-1.71.51.31.12.2-1.6-1.71.7-1.71.2-1.61.7-1.5-1.6-1.8-2.11.91.9-0.02.5-2.5
Patch foraging total patch changes 12 sec2.43.15.6-1.1-1.3-1.5-1.51.41.21.12.0-2.2-2.01.3-2.01.4-2.02.0-1.9-2.1-1.3-2.22.12.10.42.4-2.3
Patch foraging total patch changes 18 sec9.211.816.3-2.8-3.0-3.3-3.33.43.23.03.5-3.9-3.92.2-4.03.5-4.04.0-3.9-3.9-2.3-4.04.04.0-1.03.3-3.2
Patch foraging total patch changes 24 sec7.49.112.9-2.8-2.9-3.0-3.03.02.82.73.1-3.6-3.51.8-3.52.9-3.43.4-3.4-3.3-2.5-3.43.23.2-1.12.9-2.9
Patch foraging total patch changes 6 sec3.65.49.4-1.4-1.5-1.8-1.81.91.61.62.3-2.8-2.80.8-2.82.1-3.03.0-2.9-2.9-1.4-3.12.92.90.42.6-2.6
Patch foraging time to switch 0 sec2.74.17.31.81.82.12.1-2.2-2.2-2.3-1.72.32.1-1.12.2-2.42.3-2.32.22.20.62.7-2.6-2.61.6-0.90.6
Patch foraging water rate 0 sec3.45.49.3-2.0-1.9-2.3-2.32.42.42.32.1-2.7-2.51.4-2.72.7-2.62.6-2.7-2.6-0.6-3.03.03.0-1.31.5-1.2
Patch foraging water rate 12 sec0.91.43.7-1.1-1.0-1.2-1.21.31.31.30.8-1.1-1.00.8-1.11.3-1.01.0-1.1-1.1-0.3-1.91.81.9-1.20.3-0.2
Patch foraging water rate 18 sec0.30.41.2-0.2-0.2-0.2-0.20.50.50.6-0.1-0.8-0.6-0.6-0.80.9-0.80.7-0.8-0.70.5-1.11.01.0-0.3-0.30.4
Patch foraging water rate 24 sec1.42.04.9-0.6-0.4-0.8-0.81.21.31.40.2-1.7-1.3-0.6-1.72.0-1.71.7-1.7-2.01.0-2.12.22.2-0.8-0.40.6
Patch foraging water rate 6 sec0.50.74.00.80.90.60.6-0.3-0.10.2-1.3-0.10.3-1.5-0.10.5-0.10.0-0.2-0.12.0-0.10.10.1-0.3-1.71.9
Seeking ratio, delayed vs. immediate footshock1.41.63.81.01.10.90.9-1.0-0.8-0.7-1.21.61.4-0.21.6-1.21.5-1.61.51.51.11.3-1.4-1.3-0.6-1.81.9
Distance traveled before self-admin0.80.81.8-1.4-1.3-1.0-1.11.11.11.00.8-1.1-0.9-0.0-1.01.0-0.80.8-0.9-0.5-0.9-0.60.60.6-1.00.5-0.6
Distance traveled after self-admin0.60.74.01.01.10.80.8-0.5-0.4-0.2-1.1-0.40.1-2.0-0.20.4-0.20.2-0.4-0.01.6-0.70.70.80.6-1.21.1
Extensor digitorum longus weight0.10.41.60.90.70.70.7-0.8-1.0-1.1-0.10.50.40.30.6-1.00.6-0.70.50.5-0.10.1-0.1-0.01.30.4-0.6
Bone: elastic displacement0.70.82.51.21.31.11.1-0.9-0.8-0.6-1.30.60.5-1.60.5-0.30.4-0.30.30.41.50.2-0.2-0.20.5-1.31.4
Bone: elastic work4.45.68.52.92.92.92.9-2.8-2.8-2.7-2.62.12.3-2.72.2-2.22.0-2.02.02.12.52.0-1.9-1.92.6-1.71.6
Bone: endosteal estimation0.71.57.8-1.6-1.8-1.4-1.40.90.70.41.9-0.1-0.42.8-0.0-0.40.0-0.10.20.0-2.5-0.20.10.2-0.71.9-1.9
Bone: endosteal perimeter0.61.35.4-1.6-1.7-1.4-1.41.00.90.71.7-0.4-0.62.3-0.30.1-0.30.3-0.1-0.4-2.0-0.60.60.6-1.01.4-1.4
Epididymis fat weight6.916.020.43.93.94.34.3-4.4-4.3-4.2-4.04.14.4-3.24.3-4.24.5-4.54.34.32.74.4-4.3-4.32.8-2.92.6
Delta time in closed arm before/after self-admin0.00.00.1-0.0-0.0-0.1-0.10.20.10.10.1-0.3-0.2-0.0-0.30.3-0.20.2-0.3-0.10.1-0.10.10.10.20.3-0.3
Delta time in open arm before/after self-admin1.71.63.41.51.41.61.6-1.6-1.6-1.6-1.21.11.2-1.81.1-1.31.1-1.11.11.21.01.1-0.9-0.91.7-0.60.4
Diff in mean of infusions in LGA sessions0.00.00.1-0.1-0.1-0.1-0.10.10.0-0.00.20.0-0.10.2-0.1-0.0-0.10.1-0.1-0.10.0-0.10.00.00.10.3-0.1
Delay discount exponential model param0.40.41.00.80.90.90.9-0.7-0.7-0.6-0.90.40.6-1.00.4-0.40.5-0.50.40.60.90.6-0.5-0.50.6-0.70.6
Extinction: sum of active levers before priming0.10.10.90.20.20.20.2-0.1-0.00.1-0.3-0.4-0.2-0.9-0.40.3-0.40.4-0.40.10.50.00.10.00.2-0.30.3
Active lever presses in extinction session 62.32.23.41.51.51.61.6-1.7-1.7-1.7-1.41.61.6-1.41.6-1.61.7-1.71.61.80.91.4-1.4-1.41.3-0.80.6
Bone: final force4.06.510.63.33.33.13.1-2.9-2.9-2.8-2.91.92.6-3.12.0-2.22.1-2.21.92.22.92.0-2.0-2.02.6-2.11.9
Bone: final moment3.86.29.83.13.13.03.0-2.9-2.9-2.7-2.82.02.5-2.82.1-2.32.2-2.22.02.22.62.1-2.1-2.02.5-2.01.8
Food consumed during 24 hour testing period2.53.07.70.70.40.91.0-1.6-1.8-2.10.22.41.61.82.2-2.82.1-2.12.32.0-1.61.9-1.8-1.71.51.0-1.3
Glucose1.01.52.81.11.11.21.2-1.2-1.2-1.1-1.21.41.3-0.61.3-1.31.3-1.31.31.60.71.7-1.5-1.50.4-1.11.0
Heart weight2.33.34.52.02.02.12.1-2.1-2.0-2.0-2.01.91.9-1.91.9-1.81.8-1.81.81.71.71.6-1.5-1.41.5-1.61.5
Delay discount hyperbolic model param0.50.51.11.01.01.01.0-0.8-0.8-0.7-1.00.40.6-1.10.4-0.40.6-0.50.30.51.00.5-0.5-0.50.9-0.70.6
Intermittent access intake day 1-15 change0.70.72.5-0.2-0.20.00.0-0.3-0.3-0.3-0.01.60.81.41.4-1.21.1-1.11.40.8-0.90.7-0.7-0.6-0.9-0.60.4
Intermittent access intake escalation0.70.73.2-0.4-0.4-0.2-0.2-0.1-0.1-0.10.31.40.71.81.2-1.10.9-0.91.30.7-1.20.7-0.6-0.6-1.1-0.30.2
Intermittent access intake escalation 20.80.82.7-0.3-0.4-0.1-0.1-0.3-0.4-0.50.41.40.71.61.2-1.31.1-1.11.31.0-1.40.9-0.8-0.8-0.40.3-0.5
Intermitt. access day 1 inactive lever presses0.30.30.8-0.4-0.4-0.5-0.50.50.50.40.5-0.5-0.30.7-0.40.4-0.20.3-0.3-0.7-0.5-0.90.80.8-0.30.4-0.5
Intermitt. access day 15 inactive lever presses1.21.32.51.01.01.11.1-1.3-1.3-1.4-0.71.51.30.21.5-1.61.2-1.21.51.40.21.1-1.1-1.10.9-0.50.3
Intermitt. access escalation Index1.51.31.91.31.21.21.2-1.3-1.3-1.4-1.01.31.2-0.71.3-1.31.3-1.31.21.30.81.0-1.0-1.01.2-0.50.4
Intermittent access day 1 total infusions1.61.83.01.61.71.51.5-1.4-1.3-1.2-1.61.31.5-0.81.3-1.21.5-1.51.41.31.60.9-0.9-0.90.5-1.71.7
Intermittent access day 15 total infusions1.71.94.61.11.11.11.1-1.3-1.2-1.1-1.12.21.60.61.9-1.81.9-1.92.01.50.31.1-1.1-1.0-0.2-1.51.4
Intermittent access terminal intake (last 3 days)1.61.83.91.21.21.21.2-1.3-1.3-1.2-1.12.01.60.31.8-1.71.8-1.71.91.40.51.0-1.0-0.90.1-1.41.2
Intermittent access total infusions1.71.93.21.51.51.41.4-1.5-1.5-1.5-1.21.71.60.01.7-1.71.8-1.81.71.40.71.0-1.0-0.90.8-1.00.8
Intermittent access day 1 locomotion0.20.20.50.40.40.40.4-0.5-0.5-0.5-0.30.40.5-0.10.5-0.60.5-0.50.50.70.20.6-0.7-0.70.4-0.20.1
Intermittent access day 15 total locomotion0.20.21.2-0.5-0.4-0.4-0.40.20.30.30.10.50.20.90.5-0.20.3-0.30.60.2-0.4-0.0-0.00.0-1.1-0.40.5
Intermittent access total locomotion0.00.00.3-0.2-0.2-0.1-0.10.00.0-0.00.10.20.20.50.3-0.20.2-0.10.40.1-0.20.0-0.1-0.1-0.20.1-0.1
Intermittent access standard deviation0.80.86.9-0.9-0.8-0.9-0.80.50.60.60.70.80.12.60.7-0.50.6-0.50.70.1-1.6-0.10.10.2-1.9-0.30.1
Left kidney weight0.92.44.01.71.81.81.8-1.7-1.5-1.4-2.01.61.6-1.51.6-1.31.6-1.51.51.21.91.2-1.1-1.10.7-2.02.0
Right kidney weight0.92.64.21.92.02.01.9-1.8-1.7-1.6-2.11.61.6-1.81.6-1.41.5-1.41.41.11.81.0-0.9-0.91.1-1.91.8
Cocaine induced anxiety1.31.54.6-1.3-1.4-1.3-1.31.00.90.71.7-1.0-1.21.8-1.00.5-0.90.9-0.9-0.8-1.9-0.80.80.7-0.12.1-2.1
Post-drug Anxiety0.40.42.8-0.1-0.2-0.2-0.20.1-0.1-0.30.8-0.4-0.50.7-0.5-0.1-0.40.4-0.4-0.4-1.0-0.30.20.21.01.6-1.7
Baseline Anxiety2.72.84.82.22.12.12.1-2.0-2.0-1.9-1.81.61.7-1.91.5-1.51.4-1.31.51.21.81.3-1.3-1.31.9-1.21.2
Tail length1.34.07.22.52.42.52.5-2.4-2.5-2.5-1.91.71.9-2.11.7-2.01.9-1.91.72.01.81.6-1.6-1.52.7-0.80.7
Length with tail2.710.114.43.83.83.73.7-3.6-3.6-3.4-3.43.13.1-3.43.1-3.02.9-2.92.93.02.92.9-2.8-2.72.8-2.52.3
Length without tail1.43.14.31.91.91.91.9-1.9-1.8-1.7-1.92.11.8-1.72.1-1.81.7-1.71.81.51.21.8-1.8-1.80.9-1.81.6
Times rat made contact with spout0.20.21.1-0.6-0.6-0.6-0.60.50.60.50.40.00.01.0-0.00.20.1-0.10.20.1-0.30.10.00.1-1.0-0.00.1
Lifetime Intake1.11.32.31.31.31.11.1-1.2-1.2-1.2-0.91.41.30.21.3-1.41.5-1.51.41.10.80.7-0.7-0.60.6-0.90.9
Liver weight, left1.01.62.31.51.51.41.4-1.4-1.4-1.3-1.41.31.4-0.81.4-1.31.2-1.21.41.11.21.2-1.1-1.10.9-1.31.2
Liver weight, right1.82.96.62.22.32.12.0-1.7-1.6-1.3-2.41.21.7-2.61.4-0.91.1-1.21.30.92.50.6-0.7-0.60.9-2.42.4
Locomotor activity0.50.84.1-0.9-1.0-0.7-0.70.40.20.01.4-0.3-0.61.4-0.3-0.2-0.50.5-0.2-0.5-1.9-0.40.50.50.51.9-2.0
Locomotor testing distance1.22.05.9-1.7-1.8-1.5-1.51.21.00.92.0-0.9-1.42.0-1.00.5-1.11.2-0.9-1.1-2.4-1.01.00.9-0.42.1-2.2
Locomotor testing rearing2.74.27.3-2.7-2.7-2.4-2.42.32.22.12.3-1.7-2.02.2-1.71.6-1.91.9-1.5-1.9-2.5-1.91.81.8-1.91.6-1.6
Locomotion in novel chamber1.41.74.92.02.01.61.6-1.3-1.1-0.9-1.90.70.9-2.10.6-0.40.7-0.70.50.72.20.6-0.6-0.61.0-1.81.7
Locomotion in novel chamber post-restriction0.10.10.4-0.4-0.4-0.3-0.30.30.30.30.2-0.6-0.4-0.2-0.50.4-0.30.3-0.5-0.0-0.4-0.00.10.1-0.10.3-0.4
Fecal boli incidents, locomotor time 10.10.10.2-0.1-0.2-0.3-0.20.30.30.20.3-0.4-0.1-0.1-0.30.4-0.20.2-0.2-0.20.1-0.10.30.30.00.4-0.3
Change in fecal boli incidents, locomotor task0.80.71.20.80.80.90.9-0.9-0.9-0.8-0.90.81.0-0.60.9-0.80.7-0.70.91.01.10.7-0.9-0.90.5-0.91.0
Time >=10cm from walls, locomotor time 10.40.42.70.40.50.30.3-0.2-0.10.1-0.70.70.40.00.4-0.10.2-0.20.30.31.00.1-0.1-0.1-0.8-1.41.6
Bouts of movement, locomotor time 11.41.55.8-1.2-1.0-1.1-1.11.41.61.80.1-0.8-0.9-0.1-1.01.6-1.01.0-1.0-1.10.4-1.31.11.1-2.4-1.31.4
Total resting periods, locomotor time 11.31.45.3-1.1-0.9-1.1-1.11.41.61.80.2-0.8-1.0-0.0-1.01.6-1.01.0-1.1-1.10.2-1.21.11.1-2.3-1.11.2
Rest time, locomotor task time 10.20.20.8-0.3-0.4-0.2-0.2-0.0-0.1-0.20.50.50.30.90.5-0.60.3-0.30.60.5-0.50.5-0.4-0.4-0.10.5-0.5
Distance moved, locomotor task time 10.50.51.50.10.1-0.2-0.20.50.50.7-0.2-0.9-0.8-0.7-0.81.1-0.90.9-1.1-1.10.3-1.20.90.9-0.3-0.40.3
Vertical activity count, locomotor time 10.10.10.20.30.30.20.2-0.2-0.2-0.2-0.20.20.30.20.3-0.20.4-0.40.20.1-0.40.1-0.3-0.30.1-0.1-0.0
Time >=10cm from walls, locomotor time 22.12.23.41.51.41.41.4-1.6-1.5-1.5-1.31.81.6-0.21.7-1.81.6-1.61.81.70.71.6-1.7-1.70.6-1.31.2
Bouts of movement, locomotor time 20.20.31.4-0.00.1-0.1-0.10.40.50.7-0.5-0.2-0.0-0.4-0.10.7-0.10.1-0.2-0.10.9-0.10.10.1-1.0-1.11.2
Total resting periods, locomotor time 20.20.21.10.10.2-0.1-0.10.30.40.5-0.5-0.10.0-0.5-0.10.6-0.20.1-0.1-0.00.9-0.10.20.1-0.8-1.01.1
Rest time, locomotor task time 20.20.22.10.20.30.10.10.00.00.1-0.1-0.4-0.3-0.6-0.40.4-0.70.6-0.5-0.21.5-0.20.30.30.4-0.10.5
Distance moved, locomotor task time 20.80.94.1-1.2-1.2-1.2-1.21.01.11.01.0-0.5-0.81.6-0.50.6-0.30.4-0.5-0.7-2.0-0.90.50.5-1.30.6-0.9
Vertical activity count, locomotor time 20.70.75.0-0.6-0.8-0.7-0.70.40.30.11.2-0.0-0.41.8-0.1-0.2-0.00.0-0.0-0.3-2.2-0.20.20.2-0.01.5-1.8
Light reinforcement 11.01.74.2-2.0-2.0-1.7-1.71.61.61.51.5-0.7-1.22.0-0.80.8-0.70.7-0.8-0.5-1.9-0.40.40.3-2.10.7-0.7
Light reinforcement 20.20.31.9-0.6-0.5-0.5-0.50.40.50.60.10.30.00.70.30.10.2-0.20.20.4-0.60.4-0.6-0.6-1.4-0.50.5
Bone: marrow area0.81.67.8-1.8-1.9-1.5-1.41.00.80.52.0-0.2-0.52.8-0.1-0.3-0.10.00.1-0.1-2.5-0.30.20.3-0.81.9-1.9
Bone: maximum diameter0.40.71.80.80.90.80.8-0.7-0.6-0.5-1.10.70.9-0.90.7-0.50.7-0.80.80.61.20.4-0.5-0.50.0-1.31.3
Bone: maximum force3.66.210.13.23.13.03.0-3.0-3.0-2.9-2.61.92.5-2.72.1-2.42.1-2.12.02.22.32.2-2.2-2.22.9-1.51.3
Bone: maximum moment3.45.99.13.02.92.92.9-2.9-3.0-2.9-2.42.12.5-2.32.2-2.52.2-2.22.12.21.92.3-2.3-2.32.8-1.41.1
Mean time between licks in bursts1.11.56.31.41.51.51.5-1.1-0.9-0.7-2.00.61.1-2.50.5-0.20.6-0.60.60.52.00.6-0.6-0.60.5-1.91.9
Mean num. licks in bursts0.30.41.7-0.8-0.8-0.6-0.60.40.40.20.80.30.01.30.0-0.10.2-0.20.20.3-1.20.2-0.3-0.3-0.40.9-1.0
Cd content in liver3.23.66.21.21.31.71.7-1.8-1.6-1.6-1.92.52.2-0.82.4-2.02.5-2.52.42.40.82.1-2.0-2.00.0-2.01.8
Co content in liver0.50.62.2-0.9-0.7-0.8-0.80.91.01.10.3-0.5-0.60.3-0.50.9-0.70.6-0.5-0.7-0.2-0.91.01.0-1.5-0.40.5
Cu content in liver0.20.31.2-0.4-0.5-0.4-0.40.30.20.10.7-0.3-0.50.5-0.30.1-0.40.4-0.3-0.4-0.9-0.60.60.60.41.1-1.1
Fe content in liver0.10.21.1-0.6-0.6-0.5-0.50.30.30.20.7-0.2-0.21.10.0-0.1-0.10.10.00.0-0.7-0.10.20.2-0.30.6-0.5
K content in liver3.53.54.5-1.9-1.9-2.0-2.02.02.01.91.9-2.1-2.11.2-2.12.0-2.12.1-2.0-1.9-1.4-1.91.81.7-1.11.7-1.6
Mg content in liver0.30.30.6-0.6-0.5-0.6-0.60.60.60.70.5-0.7-0.60.2-0.70.7-0.70.7-0.7-0.6-0.3-0.70.50.5-0.40.4-0.3
Mn content in liver3.64.17.7-1.3-1.3-1.7-1.72.01.91.91.6-2.8-2.40.2-2.72.6-2.62.6-2.7-2.5-0.3-2.52.32.3-0.41.5-1.3
Na content in liver2.62.74.7-2.1-2.1-2.0-2.01.91.91.81.9-1.4-1.51.9-1.21.4-1.41.4-1.2-1.2-2.2-1.11.11.0-1.91.3-1.3
Rb content in liver2.22.84.92.22.22.02.0-1.9-2.0-2.0-1.71.01.6-1.91.3-1.41.3-1.31.31.52.01.4-1.4-1.42.2-0.80.9
Se content in liver1.41.73.01.71.71.61.6-1.6-1.6-1.6-1.31.41.3-1.31.2-1.31.1-1.11.10.91.20.9-0.9-0.91.7-0.60.6
Sr content in liver1.71.54.0-1.5-1.6-1.4-1.41.21.10.91.7-0.6-1.02.0-0.70.5-0.80.8-0.6-1.0-1.9-1.01.01.0-0.61.7-1.7
Zn content in liver1.51.74.10.30.50.80.8-0.8-0.6-0.4-1.41.71.5-0.61.6-1.01.6-1.61.71.40.31.4-1.5-1.5-1.2-2.01.9
Bone: minimum diameter0.91.72.51.41.31.41.4-1.5-1.6-1.6-1.01.21.4-0.91.2-1.51.3-1.31.31.30.91.3-1.4-1.41.5-0.50.4
Time in familiar zone, hab. session 10.50.42.0-0.8-0.9-0.6-0.60.40.30.11.0-0.3-0.21.4-0.2-0.20.1-0.1-0.0-0.0-1.40.1-0.1-0.1-0.11.2-1.3
Time in novel zone, hab. session 10.30.30.6-0.1-0.1-0.3-0.30.40.50.6-0.0-0.4-0.5-0.4-0.40.8-0.80.8-0.6-0.60.6-0.60.70.6-0.4-0.40.5
Total zone transitions, hab. session 10.20.30.8-0.6-0.6-0.7-0.70.70.80.70.4-0.9-0.40.5-0.60.7-0.40.4-0.5-0.5-0.1-0.40.40.4-0.80.1-0.0
Total locomotion distance, hab. session 11.52.14.3-1.7-1.5-1.7-1.71.81.92.01.1-1.9-1.40.9-1.51.8-1.31.3-1.4-1.3-0.5-1.11.21.2-2.10.20.0
Locomotion velocity, hab. session 10.91.22.8-1.1-1.0-1.2-1.21.31.51.50.5-1.5-1.00.3-1.21.5-1.01.0-1.2-1.1-0.1-1.01.11.1-1.7-0.20.4
Time in familiar zone, hab. session 20.50.52.5-0.5-0.6-0.5-0.50.20.0-0.21.0-0.2-0.21.5-0.2-0.40.1-0.1-0.00.1-1.50.1-0.1-0.10.41.4-1.6
Time in novel zone, hab. session 20.30.31.70.20.40.30.3-0.1-0.00.1-0.80.30.3-0.90.30.20.1-0.10.20.11.20.1-0.1-0.1-0.4-1.11.3
Total zone transitions, hab. session 20.50.61.9-1.2-1.2-0.9-0.90.80.70.51.0-0.6-0.31.2-0.30.2-0.10.1-0.1-0.3-1.4-0.20.30.3-0.71.0-1.0
Total locomotion distance, hab. session 23.54.68.1-2.9-2.8-2.6-2.62.52.52.32.4-2.1-1.92.4-1.81.8-1.61.6-1.6-1.6-2.5-1.61.71.7-2.31.7-1.7
Locomotion velocity, hab. session 23.64.98.0-2.8-2.8-2.7-2.72.62.62.52.3-2.3-2.12.1-2.02.1-1.81.8-1.8-1.9-2.2-1.92.02.0-2.51.4-1.4
Novel to familiar place preference ratio0.30.31.9-0.20.0-0.0-0.00.20.40.6-0.6-0.1-0.0-0.3-0.00.30.1-0.1-0.10.30.50.4-0.3-0.3-1.3-1.41.4
Novelty place preference0.40.42.30.30.50.40.4-0.2-0.00.2-0.90.10.2-0.70.20.00.2-0.2-0.00.40.80.5-0.4-0.4-0.8-1.51.5
Time in novel zone, NPP test0.40.42.40.40.60.50.5-0.4-0.20.0-1.00.20.3-0.70.4-0.10.4-0.40.20.60.90.6-0.6-0.6-0.6-1.51.5
Total zone transitions, NPP test1.21.72.7-1.6-1.7-1.6-1.61.51.51.31.6-1.4-1.11.4-1.21.2-1.11.1-1.0-1.2-1.3-1.11.11.1-1.11.3-1.2
Total locomotion distance, NPP test4.86.510.9-3.3-3.2-3.1-3.23.13.12.92.7-2.5-2.42.6-2.32.4-2.12.1-2.1-2.2-2.4-2.02.12.1-2.91.7-1.5
Locomotion velocity, NPP test5.17.311.3-3.4-3.3-3.3-3.33.23.33.22.7-2.7-2.62.4-2.62.8-2.42.4-2.4-2.4-2.3-2.32.42.3-3.11.5-1.3
Intraocular pressure0.60.81.51.01.10.90.9-0.9-0.8-0.7-1.11.20.9-0.91.0-0.70.9-0.90.90.90.70.7-0.6-0.60.1-1.21.1
Delta distance traveled before/after self-admin0.90.94.11.71.71.21.2-0.9-0.9-0.8-1.10.10.4-1.30.1-0.10.1-0.1-0.0-0.12.0-0.60.60.71.4-0.80.9
Delta ambulatory time before/after self-admin0.91.04.11.71.71.31.3-1.1-1.1-1.1-1.10.30.5-1.10.3-0.30.3-0.30.10.02.0-0.50.50.61.7-0.60.7
Parametrial fat weight3.36.410.03.12.93.03.0-3.1-3.2-3.2-2.32.52.6-2.02.6-2.82.5-2.52.42.41.82.2-2.2-2.23.1-1.00.8
Pavlov. Cond. lever latency1.41.82.91.41.51.51.5-1.5-1.4-1.3-1.51.71.3-1.21.4-1.31.3-1.31.31.31.11.3-1.3-1.30.9-1.31.2
Pavlov. Cond. magazine entry latency0.81.12.81.00.81.01.0-1.2-1.4-1.5-0.40.91.0-0.11.1-1.41.0-1.01.01.10.11.0-1.0-1.01.70.4-0.6
Pavlov. Cond. change in total contacts0.30.30.80.0-0.0-0.1-0.10.20.20.20.2-0.9-0.7-0.4-0.80.6-0.70.7-0.8-0.70.3-0.70.70.70.50.4-0.4
Pavlov. Cond. index score0.10.20.9-0.2-0.3-0.2-0.20.1-0.0-0.10.6-0.4-0.20.6-0.2-0.1-0.20.2-0.2-0.2-0.5-0.30.30.30.50.9-1.0
Pavlov. Cond. latency score0.30.41.1-0.5-0.6-0.6-0.60.50.40.30.9-0.8-0.60.7-0.60.3-0.50.5-0.6-0.6-0.6-0.70.70.70.21.1-1.1
Pavlov. Cond. lever contacts1.51.72.8-1.3-1.4-1.4-1.41.41.31.11.5-1.7-1.31.1-1.31.2-1.21.2-1.2-1.3-1.1-1.41.41.4-0.61.4-1.3
Pavlov. Cond. magazine entry number1.01.33.3-1.3-1.2-1.3-1.31.41.51.60.7-1.0-1.10.7-1.11.4-1.01.0-1.0-1.0-0.6-1.11.11.1-1.8-0.00.2
Pavlov. Cond. intertrial magazine entries0.30.40.9-0.3-0.2-0.5-0.50.60.60.70.3-0.3-0.9-0.0-0.50.8-0.90.9-0.9-0.9-0.2-0.90.90.9-0.40.0-0.0
Pavlov. Cond. lever-magazine prob. diff.0.20.21.2-0.2-0.3-0.2-0.20.1-0.0-0.20.7-0.4-0.20.7-0.1-0.2-0.10.1-0.1-0.2-0.6-0.30.30.30.61.0-1.1
Pavlov. Cond. response bias0.10.20.60.30.20.30.3-0.4-0.5-0.60.10.20.30.20.3-0.60.4-0.40.40.3-0.20.3-0.3-0.30.80.6-0.6
Pavlov. Cond. lever latency0.30.51.1-0.1-0.0-0.2-0.20.50.50.7-0.1-0.9-0.8-0.8-0.81.0-1.01.1-1.0-0.90.1-0.80.90.9-0.2-0.20.1
Pavlov. Cond. magazine entry latency0.40.53.3-0.6-0.7-0.7-0.70.30.20.11.2-0.1-0.41.8-0.1-0.4-0.10.1-0.1-0.1-1.2-0.10.10.1-0.11.1-1.2
Pavlov. Cond. change in total contacts0.00.00.2-0.2-0.2-0.2-0.20.20.20.20.10.10.10.3-0.10.1-0.00.0-0.0-0.00.5-0.20.10.1-0.5-0.20.5
Pavlov. Cond. index score0.10.21.10.0-0.1-0.1-0.1-0.2-0.3-0.40.40.40.31.00.3-0.70.4-0.50.50.4-0.20.3-0.4-0.40.20.5-0.4
Pavlov. Cond. latency score0.10.10.9-0.1-0.1-0.2-0.2-0.1-0.1-0.20.40.30.21.00.2-0.50.3-0.30.30.2-0.20.1-0.3-0.3-0.00.3-0.2
Pavlov. Cond. lever contacts0.20.31.4-0.2-0.3-0.1-0.1-0.2-0.3-0.50.60.50.31.20.4-0.80.5-0.60.60.5-0.40.4-0.4-0.40.40.9-0.7
Pavlov. Cond. magazine entry number0.10.10.5-0.4-0.3-0.1-0.10.30.40.5-0.2-0.3-0.3-0.7-0.30.7-0.40.4-0.4-0.4-0.0-0.30.30.3-0.4-0.30.2
Pavlov. Cond. intertrial magazine entries0.20.31.6-0.2-0.4-0.1-0.1-0.1-0.2-0.40.60.2-0.10.60.1-0.4-0.00.00.1-0.1-1.0-0.10.20.20.81.1-1.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.90.20.10.10.1-0.3-0.4-0.50.30.50.30.90.4-0.80.5-0.50.50.5-0.10.4-0.4-0.40.40.4-0.3
Pavlov. Cond. response bias0.20.21.00.1-0.00.00.0-0.3-0.5-0.60.50.40.31.00.3-0.80.4-0.50.40.4-0.20.3-0.4-0.40.60.8-0.7
Time in closed arm before self-admin0.10.10.40.20.20.30.3-0.4-0.5-0.50.00.20.20.50.3-0.60.2-0.20.30.1-0.10.4-0.4-0.40.70.2-0.3
Time in closed arm after self-admin0.10.10.30.50.50.40.4-0.4-0.4-0.3-0.40.00.10.00.1-0.20.1-0.10.00.10.40.1-0.3-0.30.5-0.20.1
Time in open arm before self-admin1.11.24.9-1.2-1.0-1.2-1.31.41.61.60.5-0.9-0.80.5-0.91.4-0.80.8-0.9-1.0-0.4-1.11.11.2-2.2-0.50.7
Time in open arm after self-admin0.30.32.40.40.50.30.3-0.1-0.00.1-0.6-0.20.1-1.5-0.20.4-0.10.1-0.2-0.11.0-0.50.70.8-0.0-0.80.9
Bone: periosteal estimation0.71.42.11.21.11.31.3-1.4-1.4-1.4-0.91.21.4-0.61.3-1.51.3-1.31.41.30.71.1-1.1-1.11.2-0.50.5
Bone: periosteal perimeter0.10.20.80.40.40.40.4-0.4-0.3-0.3-0.60.40.6-0.40.5-0.30.5-0.60.60.40.70.3-0.3-0.3-0.2-0.80.9
Bone: post-yield work0.71.02.20.30.20.50.5-0.8-0.9-1.0-0.01.21.00.81.3-1.51.1-1.11.21.2-1.11.4-1.4-1.40.60.4-0.7
Progressive ratio test 1 active lever presses0.10.10.50.40.40.20.2-0.2-0.1-0.1-0.40.30.2-0.00.2-0.10.5-0.40.20.20.6-0.1-0.1-0.1-0.2-0.60.7
Progressive ratio test 1 breakpoint0.10.10.40.40.40.20.2-0.2-0.1-0.1-0.30.30.20.10.2-0.10.4-0.40.20.00.7-0.20.00.1-0.1-0.50.6
Progressive ratio test 1 inactive lever presses0.20.20.9-0.7-0.7-0.7-0.70.60.60.60.6-0.3-0.20.9-0.10.2-0.10.3-0.0-0.3-0.5-0.30.20.2-1.00.2-0.1
Progressive ratio test 2 active lever presses0.10.10.5-0.1-0.0-0.0-0.0-0.00.00.1-0.20.50.30.60.4-0.20.6-0.50.40.3-0.0-0.20.20.2-0.7-0.60.6
Progressive ratio test 2 breakpoint0.10.20.40.30.40.30.3-0.3-0.3-0.2-0.40.60.40.10.4-0.40.7-0.60.50.40.3-0.00.10.1-0.2-0.60.7
Progressive ratio test 2 inactive lever presses0.50.64.0-0.9-0.8-0.7-0.70.40.50.40.60.50.22.00.5-0.40.6-0.50.60.4-1.30.0-0.00.1-1.5-0.1-0.0
Incentive Sensitization - Responses0.10.10.6-0.2-0.1-0.1-0.10.10.20.2-0.20.30.30.30.40.00.3-0.30.40.20.0-0.40.50.6-0.8-0.60.6
Incentive Sensitization - Breakpoint0.10.10.6-0.3-0.2-0.2-0.20.20.30.3-0.00.20.20.40.20.10.2-0.10.20.1-0.1-0.40.60.7-0.7-0.40.4
Sum of active levers in priming session hrs 5-60.00.00.1-0.1-0.1-0.0-0.00.00.0-0.00.1-0.2-0.2-0.3-0.30.1-0.30.3-0.3-0.00.10.00.10.00.30.3-0.3
Progressive ratio0.10.20.8-0.2-0.1-0.3-0.30.40.50.6-0.2-0.1-0.20.0-0.10.5-0.10.2-0.1-0.30.5-0.50.40.5-0.9-0.70.8
Food seeking constrained by brief footshock2.53.14.7-2.0-1.9-2.0-2.02.12.12.21.6-1.7-1.81.7-1.72.0-1.81.8-1.6-1.8-1.0-1.91.71.7-1.90.8-0.5
Seeking ratio, punishment vs. effort1.31.62.7-1.6-1.6-1.5-1.51.41.31.31.5-1.3-1.21.4-1.31.0-1.21.2-1.2-1.1-1.5-0.90.80.8-0.91.3-1.2
Retroperitoneal fat weight8.126.635.05.95.75.95.9-5.9-5.9-5.8-5.15.35.5-4.25.3-5.35.1-5.15.24.94.24.8-5.0-5.04.9-3.43.1
Reaction time number correct0.30.51.2-0.2-0.2-0.4-0.40.60.60.60.2-1.1-0.7-0.6-1.11.1-0.80.8-1.1-0.90.6-0.80.90.90.00.3-0.1
Reaction time mean minus median0.70.92.00.60.50.80.8-1.0-1.1-1.2-0.31.10.80.21.1-1.31.1-1.01.01.3-0.01.4-1.1-1.11.10.2-0.3
Reaction time mean minus median AUC0.10.10.40.10.10.20.2-0.3-0.3-0.4-0.00.30.30.30.4-0.50.4-0.40.30.60.00.7-0.3-0.30.2-0.00.0
Reaction time num false alarms0.30.42.6-0.3-0.1-0.5-0.50.60.80.9-0.1-0.1-0.20.0-0.10.6-0.30.3-0.2-0.40.4-0.70.50.5-1.6-1.01.2
Reaction time num false alarms AUC0.50.72.4-0.5-0.4-0.8-0.80.91.11.20.3-0.6-0.70.2-0.61.0-0.80.8-0.7-1.00.2-1.21.01.0-1.6-0.60.8
Reaction time trials correct on left0.30.51.2-0.2-0.2-0.4-0.40.60.60.60.2-1.1-0.7-0.6-1.11.1-0.80.8-1.1-0.90.6-0.80.90.90.00.3-0.1
Reaction time trials on left0.40.51.3-0.2-0.2-0.4-0.40.60.60.60.2-1.1-0.8-0.6-1.11.1-0.80.8-1.1-0.90.6-0.80.90.90.00.3-0.1
Reaction time mean0.40.51.20.60.50.70.7-0.8-0.9-1.0-0.20.80.50.30.7-1.10.8-0.70.61.0-0.21.0-0.7-0.70.90.2-0.3
Reaction time mean AUC0.40.61.40.60.50.70.7-0.9-1.0-1.0-0.30.90.60.30.8-1.20.8-0.80.71.1-0.20.9-0.8-0.71.00.2-0.3
Median of all reaction times0.20.20.60.40.30.40.4-0.5-0.6-0.6-0.10.50.30.50.4-0.80.5-0.50.40.7-0.40.6-0.5-0.50.60.2-0.3
Reaction time omissions0.20.20.5-0.3-0.3-0.4-0.40.50.50.50.3-0.6-0.60.3-0.60.5-0.60.6-0.7-0.50.1-0.60.70.7-0.50.00.1
Reaction time false alarm rate0.20.32.2-0.4-0.3-0.6-0.60.60.70.80.1-0.1-0.30.4-0.10.5-0.40.4-0.1-0.5-0.1-0.70.50.5-1.5-0.80.8
Reaction time premature initiation rate0.10.20.8-0.0-0.00.10.1-0.2-0.1-0.1-0.20.30.2-0.20.4-0.30.4-0.40.40.6-0.10.6-0.9-0.9-0.4-0.40.4
Reaction time premature initiations0.10.10.4-0.3-0.2-0.3-0.30.40.40.50.0-0.6-0.4-0.5-0.50.5-0.30.4-0.6-0.30.2-0.2-0.0-0.1-0.4-0.20.3
Std. dev. reaction times0.50.71.50.70.60.80.8-1.0-1.0-1.1-0.41.00.80.11.0-1.21.1-0.90.91.20.11.1-0.9-0.91.00.1-0.1
Reaction time trials completed0.40.51.3-0.2-0.2-0.4-0.40.60.60.60.2-1.1-0.8-0.6-1.11.1-0.80.8-1.1-0.90.6-0.80.90.90.00.3-0.1
Reaction time trials AUC0.30.41.1-0.1-0.1-0.3-0.30.50.50.50.2-1.1-0.7-0.7-1.01.0-0.70.7-1.0-0.80.6-0.80.90.90.20.4-0.2
Run reversals in cocaine runway, females0.40.40.80.80.80.60.6-0.7-0.7-0.6-0.60.90.60.00.9-0.70.5-0.50.80.60.30.7-0.8-0.80.4-0.50.4
Run reversals in cocaine runway, males0.20.21.20.10.10.00.00.0-0.1-0.20.3-0.6-0.2-0.4-0.40.4-0.50.5-0.4-0.50.7-0.30.40.31.10.9-0.6
Latency to leave start box in cocaine runway8.69.311.03.33.33.33.3-3.3-3.2-3.2-3.13.23.3-2.43.1-3.03.1-3.23.13.22.53.3-3.2-3.22.2-2.32.3
Latency to leave start box in cocaine runway, F8.79.512.03.33.23.33.3-3.4-3.4-3.3-2.93.33.3-2.03.3-3.33.2-3.33.33.42.03.5-3.4-3.42.3-2.01.9
Latency to leave start box in cocaine runway, M0.80.81.61.11.21.01.0-0.9-0.8-0.7-1.30.70.8-1.20.6-0.40.7-0.70.60.71.30.6-0.6-0.60.4-1.31.2
Std. dev. time between licks in bursts0.20.21.2-0.5-0.3-0.1-0.10.30.40.6-0.4-0.1-0.0-0.5-0.10.4-0.10.1-0.1-0.1-0.0-0.10.10.1-1.1-1.00.9
Total sessions with >9 infusions0.30.41.00.60.50.40.4-0.6-0.7-0.80.00.80.51.00.7-1.00.7-0.70.70.60.2-0.0-0.1-0.10.60.1-0.1
Short access day 1 total inactive lever presses1.11.22.40.80.70.80.8-1.0-1.0-1.1-0.51.51.30.21.4-1.51.6-1.51.51.3-0.11.4-1.3-1.30.4-0.30.2
Short access day 10 total inactive lever presses0.30.42.5-0.3-0.5-0.2-0.2-0.0-0.2-0.40.8-0.10.00.80.0-0.40.4-0.30.20.2-1.2-0.1-0.2-0.10.71.5-1.6
Short access day 1 total infusions0.20.20.60.50.40.30.3-0.5-0.6-0.7-0.00.70.40.60.6-0.70.8-0.70.60.60.10.0-0.1-0.00.50.2-0.1
Short access day 10 total infusions0.20.21.30.60.70.30.3-0.2-0.2-0.1-0.50.30.40.20.3-0.10.4-0.30.30.11.0-0.40.30.4-0.4-1.01.1
Short access total infusions0.70.81.41.21.10.90.9-0.9-0.9-0.9-0.81.00.90.11.0-1.01.2-1.11.00.81.00.2-0.3-0.20.5-0.80.9
Short access day 1 locomotion0.10.10.3-0.0-0.0-0.1-0.10.20.20.30.0-0.3-0.4-0.3-0.40.4-0.40.5-0.4-0.50.5-0.50.50.5-0.1-0.20.3
Short access day 10 total locomotion2.42.63.7-1.9-1.9-1.9-1.91.91.91.81.7-1.5-1.61.7-1.31.6-1.71.7-1.3-1.6-1.5-1.51.51.4-1.61.1-1.1
Short access total locomotion2.02.12.7-1.6-1.6-1.6-1.61.61.51.51.5-1.5-1.51.3-1.31.4-1.61.6-1.4-1.5-0.9-1.61.61.6-1.01.0-0.9
One hour access (0.3 mA shock)0.50.62.5-1.1-1.0-1.0-1.00.91.00.90.8-0.3-0.51.6-0.40.4-0.30.3-0.3-0.4-0.9-0.50.50.5-1.40.1-0.1
Compulsive drug intake0.40.50.8-0.7-0.7-0.7-0.70.80.80.70.6-0.9-0.80.1-0.80.9-0.80.7-0.9-0.5-0.3-0.70.70.7-0.40.5-0.5
One hour access (shock baseline)0.20.21.10.00.00.00.0-0.2-0.2-0.30.10.60.51.00.6-0.70.7-0.50.70.3-0.50.4-0.3-0.3-0.2-0.0-0.0
Social response proportion1.81.96.11.41.21.51.5-1.7-1.9-2.1-0.61.21.3-0.41.3-1.91.5-1.51.41.30.01.1-0.9-0.92.50.6-0.9
Social responses0.10.10.4-0.0-0.1-0.1-0.10.10.0-0.00.3-0.5-0.3-0.0-0.40.1-0.20.2-0.4-0.2-0.3-0.00.40.40.40.5-0.6
Social time0.30.41.10.00.10.20.2-0.3-0.2-0.1-0.40.70.60.70.8-0.61.0-1.00.80.50.10.8-0.4-0.4-0.8-0.90.8
Soleus weight0.20.62.5-0.4-0.3-0.6-0.60.81.01.1-0.0-0.8-0.50.1-0.60.9-0.50.5-0.6-0.70.4-0.80.70.8-1.6-1.01.1
Bone: stiffness2.33.65.82.42.42.32.3-2.2-2.1-2.0-2.11.51.9-2.21.5-1.61.5-1.61.41.52.21.6-1.6-1.62.0-1.41.4
Tibialis anterior weight0.51.73.61.61.41.51.5-1.7-1.8-1.9-0.81.21.2-0.31.3-1.81.4-1.41.31.30.31.1-1.1-1.11.9-0.0-0.2
Time to tail flick, vehicle, before self-admin2.72.76.02.32.32.02.0-1.8-1.7-1.6-2.11.21.5-2.41.1-1.01.3-1.21.11.12.30.9-0.8-0.81.4-1.81.8
Time to tail flick, vehicle, after self-admin0.00.00.3-0.3-0.3-0.0-0.00.0-0.0-0.10.10.10.10.00.0-0.1-0.00.10.10.2-0.50.3-0.1-0.10.00.2-0.4
Time to tail flick, test, before self-admin0.80.81.9-0.0-0.10.20.2-0.5-0.5-0.5-0.11.20.90.91.1-1.11.2-1.21.21.3-0.51.4-1.3-1.3-0.2-0.10.1
Time to tail flick, test, after self-admin1.71.83.90.50.40.70.7-1.0-1.1-1.3-0.31.81.51.01.9-1.91.8-1.82.01.8-0.51.7-1.7-1.70.3-0.0-0.1
Delta time to tail flick, vehicle, before/after SA1.51.53.4-1.9-1.8-1.5-1.51.41.41.21.5-0.8-1.01.6-0.90.9-0.90.9-0.8-0.7-1.8-0.60.60.5-1.21.2-1.3
Delta time to tail flick, test, before/after SA0.20.20.9-0.3-0.4-0.2-0.20.0-0.1-0.30.60.20.10.60.3-0.40.1-0.10.30.1-0.6-0.10.20.20.40.9-0.9
Tibia length6.418.024.14.94.94.94.9-4.9-4.8-4.6-4.54.34.4-3.94.2-4.24.2-4.24.14.13.63.8-3.9-3.83.7-3.23.0
Ambulatory time before self-admin0.50.51.4-1.2-1.1-0.9-0.90.90.90.90.6-0.8-0.7-0.1-0.70.7-0.60.6-0.6-0.2-0.9-0.20.20.2-1.00.3-0.4
Ambulatory time after self-admin0.50.63.80.91.00.80.8-0.5-0.4-0.3-1.0-0.40.0-1.9-0.30.3-0.10.2-0.40.01.6-0.50.40.50.6-0.90.9
Bone: tissue strength0.10.10.30.30.20.20.2-0.3-0.4-0.40.10.3-0.00.20.2-0.4-0.0-0.00.1-0.1-0.30.1-0.1-0.10.50.3-0.4
Total heroin consumption0.10.10.7-0.2-0.1-0.0-0.00.20.30.4-0.4-0.10.0-0.8-0.10.4-0.10.1-0.20.10.60.3-0.2-0.2-0.5-0.60.7
Bone: trabecular number1.11.63.70.10.20.60.6-0.7-0.6-0.5-1.01.51.50.11.6-1.31.7-1.71.71.9-0.01.9-1.9-1.9-1.1-1.51.4
Bone: trabecular spacing0.60.83.21.00.90.60.6-0.4-0.5-0.5-0.2-0.7-0.5-1.3-0.80.4-0.80.8-0.9-1.01.1-1.11.11.21.80.4-0.4
Bone: trabecular thickness1.51.83.50.91.11.11.1-1.1-0.9-0.8-1.51.41.5-1.01.6-1.01.3-1.31.51.41.21.5-1.6-1.7-0.3-1.81.9
Bone: trabecular tissue density0.20.21.40.50.60.20.2-0.00.10.3-0.6-0.1-0.1-0.6-0.00.4-0.30.3-0.2-0.31.0-0.20.10.1-0.5-1.11.2
Water consumed over 24 hours0.40.51.50.1-0.00.10.1-0.4-0.6-0.80.50.60.61.20.6-1.10.8-0.80.80.6-0.90.7-0.3-0.30.60.9-1.0
Number of responses in last shaping day0.20.21.1-0.6-0.6-0.4-0.40.30.40.40.20.3-0.00.80.2-0.10.3-0.40.20.2-0.60.4-0.5-0.5-1.1-0.30.2