Hub : Genes

Msl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Msl1 0.15 0.1 1.5e-05 0.08 0.08 0.08 0.08 6.1e-05 3.1e-05 3.5e-05 6.0e-05
2 NAcc alternative polyA NM_001107048.1 0.06 0.03 6.1e-09 0.06 0.07 0.06 0.06 4.9e-08 4.0e-08 5.7e-07 1.2e-07
3 Adipose alternative polyA XM_006247304.4 0.02 0.02 4.2e-03 -0 0 0 0 5.6e-01 1.7e-01 3.0e-01 3.5e-01
4 BLA alternative polyA XM_006247304.4 0.06 0.04 4.1e-03 0.01 0.02 -0 0.01 6.7e-02 4.4e-02 3.6e-01 1.5e-01
5 BLA alternative polyA NM_001107048.1 0.06 0.04 1.9e-03 0 0.02 -0 0 2.1e-01 2.3e-02 4.2e-01 2.5e-01
6 NAcc alternative polyA XM_006247304.4 0.08 0.05 3.7e-10 0.09 0.07 0.09 0.09 5.1e-11 8.6e-09 4.5e-10 2.8e-10
7 Brain alternative polyA NM_001107048.1 0.11 0.09 1.8e-06 0.05 0.05 0.06 0.05 4.1e-05 3.2e-05 2.3e-06 2.3e-05
8 Brain alternative polyA XM_006247304.4 0.12 0.09 1.2e-06 0.05 0.05 0.06 0.05 1.3e-05 2.3e-05 1.5e-06 1.4e-05
9 Adipose isoform ratio XM_006247304.4 0.03 0.02 1.2e-03 0.01 0.01 0.01 0.01 7.4e-03 1.1e-02 4.1e-02 1.2e-02
10 PL gene expression Msl1 0.02 0.02 3.9e-03 0.02 0.01 0.01 0.01 6.6e-03 7.8e-03 4.0e-02 1.8e-02
11 Adipose isoform ratio NM_001107048.1 0.03 0.02 1.7e-03 0.01 0.01 0.01 0.01 1.1e-02 1.7e-02 4.0e-02 1.2e-02
12 Liver gene expression Msl1 0.28 0.13 0.0e+00 0.19 0.2 0.21 0.21 2.7e-20 2.9e-22 7.4e-23 6.7e-23
13 PL alternative polyA NM_001107048.1 0.12 0.09 6.0e-10 0.09 0.09 0.09 0.1 4.0e-10 7.9e-10 9.7e-10 5.5e-11
14 Brain gene expression Msl1 0.05 0.03 1.0e-05 0.05 0.04 0.04 0.04 1.1e-05 1.6e-04 9.5e-05 5.6e-05
15 PL alternative polyA XM_006247304.4 0.08 0.05 1.0e-09 0.09 0.09 0.07 0.09 3.1e-10 7.0e-10 5.2e-08 6.3e-10
16 BLA gene expression Msl1 0.08 0.06 1.6e-03 0.04 0.03 0.03 0.03 1.9e-03 9.2e-03 1.2e-02 7.7e-03
17 Adipose gene expression Msl1 0.06 0.04 1.0e-08 0.07 0.06 0.08 0.08 1.3e-08 9.5e-08 4.3e-09 3.7e-09
18 Adipose alternative polyA NM_001107048.1 0.02 0.02 1.9e-03 0 0 0 0 7.6e-02 9.1e-02 1.1e-01 2.8e-01
19 NAcc isoform ratio NM_001107048.1 0.02 0.02 5.1e-03 0.01 0 0 0 5.6e-02 1.3e-01 2.4e-01 1.6e-01
20 NAcc isoform ratio XM_006247304.4 0.02 0.02 2.7e-03 0.01 0.01 0 0 5.3e-02 6.2e-02 2.0e-01 1.4e-01
21 Brain mRNA stability Msl1 0.04 0.03 4.3e-03 0.01 0.01 -0 0.01 2.0e-02 2.0e-02 3.7e-01 6.2e-02
22 pVTA alternative polyA NM_001107048.1 0.06 0.05 9.0e-03 0.02 0 -0.01 -0 6.3e-02 3.1e-01 8.3e-01 4.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density2.54.25.41.9-2.02.02.1-2.1-2.12.0-2.0-2.0-2.02.1-2.2-2.1-2.3-2.1-2.3-2.02.12.1-1.52.11.8
Area under the delay curve0.30.31.00.5-0.50.50.5-0.6-0.40.4-0.4-0.4-0.41.0-0.6-0.8-0.8-0.8-0.7-0.40.40.4-0.30.20.6
BMI with tail2.16.99.6-3.13.0-3.0-2.92.92.6-2.62.62.52.5-2.32.32.71.92.12.22.9-2.8-2.83.0-1.5-2.6
BMI without tail0.10.31.4-0.40.5-0.5-0.50.50.5-0.40.40.50.5-0.30.10.1-0.5-0.1-0.20.4-0.7-0.71.2-0.3-0.6
Body weight4.920.728.0-5.35.0-5.1-4.94.94.6-4.74.74.64.6-5.24.44.73.94.24.14.7-4.5-4.54.5-2.7-3.8
Weight adjusted by age0.40.41.4-0.80.5-0.4-0.40.30.6-0.60.60.70.7-0.40.50.91.11.20.80.3-0.6-0.60.20.50.5
Bone surface0.10.10.9-0.20.00.00.1-0.1-0.10.2-0.2-0.2-0.20.0-0.5-0.2-0.5-0.4-0.6-0.10.20.20.40.90.2
Bone volume0.20.42.00.1-0.30.30.4-0.4-0.60.6-0.6-0.7-0.70.5-0.8-0.3-0.8-0.7-0.9-0.40.70.70.31.40.1
Breakpoint value in progressive ratio session0.20.21.7-0.0-0.30.20.2-0.3-0.40.3-0.30.20.2-1.30.10.50.70.70.5-0.4-0.2-0.2-0.60.41.0
Number of licking bursts0.20.21.00.1-0.30.30.4-0.4-0.40.3-0.3-0.3-0.30.9-0.40.0-0.5-0.2-0.1-0.50.50.50.11.0-0.2
Context. condit. distance diff. score1.31.54.9-1.01.1-1.2-1.21.21.4-1.31.31.31.3-0.71.40.91.51.31.41.6-1.0-1.00.4-2.20.0
Locomotion velocity, session 10.40.40.9-0.80.8-0.8-0.70.70.7-0.60.60.60.6-0.90.40.60.10.80.60.6-0.6-0.61.0-0.0-0.6
Locomotion distance, session 12.32.95.5-2.01.9-1.9-1.81.81.6-1.61.61.71.7-2.41.42.10.91.81.41.7-1.4-1.42.2-0.5-1.9
Locomotion velocity, session 20.10.20.8-0.40.3-0.3-0.30.30.4-0.30.30.50.5-0.90.20.1-0.00.50.30.2-0.6-0.6-0.0-0.20.3
Locomotion distance, session 20.20.31.5-0.70.5-0.5-0.40.40.2-0.20.20.40.4-1.20.00.8-0.30.50.10.2-0.1-0.10.70.8-0.8
Locomotion velocity, session 30.10.10.80.3-0.30.30.3-0.3-0.30.2-0.2-0.2-0.2-0.5-0.3-0.6-0.5-0.1-0.6-0.40.10.1-0.9-0.10.7
Locomotion distance, session 30.20.20.6-0.50.5-0.4-0.50.50.5-0.40.50.40.4-0.80.20.40.10.60.10.3-0.4-0.40.2-0.3-0.4
Stereotopy head waving bouts, day 32.73.24.81.9-1.91.91.9-1.9-1.71.8-1.8-1.8-1.82.1-1.8-2.1-1.7-1.9-2.0-1.61.51.5-1.61.02.2
Stereotopy head waving duration, day 30.20.21.30.4-0.40.30.4-0.4-0.30.4-0.4-0.4-0.40.7-0.5-0.7-0.4-0.6-0.6-0.20.10.1-0.20.11.1
Locomotion velocity, session 71.21.32.4-1.31.2-1.2-1.11.21.2-1.11.11.11.1-1.01.01.51.01.41.11.0-1.0-1.01.2-0.3-1.3
Locomotion distance, session 70.60.72.0-0.70.8-0.8-0.80.90.9-0.70.70.80.8-0.50.81.20.81.11.00.8-0.7-0.70.8-0.5-1.4
Stereotopy head waving bouts, day 70.60.71.60.6-0.80.70.8-0.8-0.70.7-0.6-0.7-0.71.2-0.9-0.8-0.9-0.8-1.3-0.70.80.8-0.50.81.1
Stereotopy head waving duration, day 70.40.51.60.4-0.60.60.6-0.7-0.50.5-0.5-0.6-0.60.7-0.8-0.8-0.8-0.6-1.1-0.70.60.6-0.40.61.3
Locomotion velocity, session 87.69.010.1-3.13.2-3.2-3.23.13.1-3.13.13.13.1-3.03.13.02.93.13.13.2-2.9-2.92.6-2.8-1.9
Locomotion distance, session 81.21.82.5-1.51.5-1.4-1.41.41.4-1.41.41.41.4-1.61.31.51.21.51.41.5-1.1-1.11.1-1.0-1.0
Degree of sensitization distance1.51.52.5-1.01.2-1.2-1.21.21.2-1.11.11.11.1-0.61.41.31.41.21.61.3-1.2-1.21.2-1.1-1.3
Degree of sensitization stereotypy0.91.02.20.8-0.90.91.0-1.0-0.90.9-0.8-0.9-0.91.5-1.0-0.8-1.0-0.9-1.2-0.91.11.1-0.71.01.0
Conditioned locomotion0.20.20.80.5-0.50.50.5-0.5-0.50.3-0.3-0.2-0.20.4-0.4-0.7-0.3-0.2-0.2-0.50.50.5-0.50.10.9
Cocaine response after cond. corrected0.70.83.20.6-0.70.80.8-0.8-0.90.8-0.8-0.9-0.91.8-1.0-0.4-0.8-0.7-0.6-0.80.90.9-0.11.50.4
Cocaine response after cond. not corrected0.91.04.70.7-0.90.91.0-1.0-1.10.9-0.9-1.0-1.02.2-1.1-0.4-0.8-0.7-0.5-0.91.01.0-0.21.60.6
Cocaine response before conditioning0.10.10.70.4-0.40.40.4-0.4-0.40.3-0.3-0.3-0.30.9-0.3-0.30.0-0.1-0.1-0.20.20.2-0.40.00.6
Saline control response0.20.30.8-0.60.5-0.5-0.40.40.5-0.50.50.50.50.60.50.90.60.70.80.6-0.5-0.50.90.1-0.3
Bone: connectivity density3.65.66.92.2-2.42.42.5-2.5-2.42.3-2.3-2.3-2.32.2-2.5-2.5-2.6-2.3-2.6-2.42.42.4-2.02.22.3
Bone: cortical apparent density6.28.211.33.4-3.13.13.0-2.9-2.93.1-3.1-3.1-3.12.8-2.8-2.9-2.8-2.6-2.8-2.72.82.8-3.11.42.1
Bone: cortical area0.10.10.40.2-0.30.30.3-0.3-0.20.2-0.2-0.3-0.30.7-0.3-0.2-0.2-0.2-0.1-0.20.30.3-0.50.20.3
Bone: cortical porosity0.10.10.80.1-0.20.30.3-0.3-0.30.3-0.3-0.1-0.10.9-0.4-0.3-0.2-0.40.0-0.30.40.40.10.90.3
Bone: cortical porosity0.10.11.0-0.1-0.10.10.2-0.2-0.20.2-0.2-0.0-0.01.0-0.30.1-0.0-0.20.2-0.10.30.30.40.90.2
Bone: cortical thickness1.11.73.61.4-1.41.41.4-1.4-1.21.2-1.2-1.2-1.21.9-1.3-1.2-1.2-0.8-1.0-1.21.31.3-1.70.51.9
Bone: cortical thickness5.76.711.42.6-2.72.72.8-2.8-2.62.5-2.5-2.6-2.62.4-2.5-2.8-2.3-2.2-2.3-2.52.62.6-2.71.73.4
Bone: cortical tissue density6.28.211.33.4-3.13.03.0-2.9-2.93.1-3.1-3.1-3.12.8-2.9-2.9-2.8-2.7-2.8-2.72.82.8-3.11.42.1
Condit. Reinf. active minus inactive responses1.11.22.71.3-1.21.21.2-1.2-1.11.1-1.0-0.9-0.90.7-1.1-1.2-1.3-0.7-1.0-1.20.90.9-1.60.41.4
Condit. Reinf. active-inactive response ratio1.21.33.41.4-1.31.31.3-1.3-1.01.1-1.0-0.9-0.90.8-1.0-1.4-1.0-0.8-1.0-1.20.90.9-1.80.11.7
Condit. Reinf. active responses1.01.33.21.2-1.21.21.2-1.2-1.11.1-1.1-0.9-0.91.0-1.1-1.1-1.2-0.7-0.9-1.21.01.0-1.80.51.4
Condit. Reinf. inactive responses0.10.20.80.2-0.30.30.3-0.3-0.40.3-0.3-0.3-0.30.9-0.4-0.1-0.3-0.1-0.1-0.40.50.5-0.50.60.3
Incentive salience index mean2.12.53.91.7-1.71.71.7-1.7-1.61.7-1.7-1.5-1.51.3-1.7-1.6-1.9-1.4-1.5-1.71.41.4-2.01.11.3
Condit. Reinf. lever presses1.01.32.41.2-1.11.21.2-1.1-1.11.3-1.3-1.1-1.11.2-1.4-0.9-1.6-1.0-1.0-1.11.01.0-1.21.10.5
Condit. Reinf. active minus inactive responses1.11.31.91.1-1.21.21.2-1.2-1.31.2-1.2-1.3-1.30.8-1.1-0.9-1.0-1.1-1.3-1.41.31.3-0.81.30.4
Condit. Reinf. active-inactive response ratio1.01.01.80.9-0.90.91.0-0.9-1.21.1-1.1-1.1-1.10.5-1.0-0.8-1.1-1.1-1.3-1.21.21.2-0.31.30.1
Condit. Reinf. active responses1.82.53.81.5-1.61.61.6-1.6-1.71.7-1.7-1.8-1.81.0-1.5-1.2-1.4-1.6-1.8-1.81.71.7-1.21.90.6
Condit. Reinf. inactive responses1.92.43.21.4-1.61.61.6-1.6-1.51.6-1.6-1.7-1.71.4-1.6-1.3-1.3-1.6-1.6-1.71.61.6-1.41.80.8
Condit. Reinf. lever presses0.10.20.50.4-0.50.50.5-0.5-0.40.3-0.3-0.4-0.40.1-0.3-0.5-0.1-0.4-0.5-0.50.40.4-0.70.20.6
Condit. Reinf. lever reinforcers received1.92.63.41.6-1.71.71.7-1.7-1.71.7-1.7-1.9-1.91.0-1.6-1.3-1.5-1.6-1.8-1.81.71.7-1.41.80.8
Conditioned reinforcement - actives0.50.51.10.9-0.90.90.9-0.8-0.80.7-0.8-0.7-0.71.0-0.2-0.2-0.0-0.20.2-1.00.90.9-0.70.5-0.2
Conditioned reinforcement - inactives1.92.23.51.9-1.61.51.5-1.4-1.91.7-1.7-1.7-1.71.0-1.2-1.5-1.1-1.7-1.3-1.51.81.8-1.20.80.1
Conditioned locomotion0.40.41.60.8-0.80.80.7-0.7-0.70.7-0.8-0.4-0.41.2-0.40.2-0.50.2-0.2-0.80.70.7-0.20.8-0.5
Patch foraging indifference point 0 sec1.83.04.62.1-1.91.91.8-1.8-1.71.7-1.7-1.8-1.81.4-1.6-1.9-1.5-1.9-1.9-1.71.61.6-2.10.80.9
Patch foraging indifference point AUC0.10.10.3-0.30.2-0.1-0.10.10.2-0.30.30.30.3-0.20.10.20.10.60.20.1-0.2-0.20.10.10.2
Delay disc. indifference point, 0s delay1.11.22.21.1-1.11.21.2-1.2-1.11.0-1.1-1.0-1.01.1-1.0-1.1-1.0-1.0-1.4-1.10.70.7-1.50.91.2
Delay disc. indifference point, 16s delay0.60.64.00.7-0.60.60.6-0.7-0.20.5-0.5-0.5-0.50.9-0.7-1.4-0.5-0.9-0.3-0.30.30.3-0.7-0.42.0
Delay disc. indifference point, 2s delay0.91.02.80.9-1.01.01.1-1.0-1.01.1-1.1-1.0-1.01.7-1.1-0.5-1.3-0.8-1.1-1.01.01.0-0.51.20.1
Delay disc. indifference point, 24s delay0.10.10.4-0.00.2-0.2-0.20.20.4-0.20.30.40.40.40.2-0.30.1-0.30.10.2-0.4-0.40.5-0.6-0.1
Delay disc. indifference point, 4s delay0.80.92.70.8-1.01.01.0-1.1-1.00.8-0.8-0.8-0.81.0-0.9-0.9-0.7-0.8-0.6-1.01.01.0-0.80.81.6
Delay disc. indifference point, 8s delay0.20.20.60.3-0.30.30.3-0.3-0.20.2-0.2-0.1-0.10.8-0.3-0.8-0.7-0.8-0.6-0.30.40.4-0.30.1-0.1
Indifference point function ln k0.00.10.50.2-0.10.10.0-0.00.2-0.00.0-0.0-0.00.20.1-0.4-0.0-0.2-0.10.1-0.3-0.3-0.2-0.70.4
Indifference point function log k0.00.10.50.2-0.10.10.0-0.00.2-0.00.0-0.0-0.00.20.1-0.4-0.0-0.2-0.10.1-0.3-0.3-0.2-0.70.4
Patch foraging total patch changes 0 sec1.32.13.51.7-1.61.61.5-1.5-1.41.4-1.4-1.5-1.51.2-1.4-1.7-1.3-1.6-1.7-1.51.41.4-1.90.60.6
Patch foraging total patch changes 12 sec5.47.08.62.7-2.72.82.8-2.8-2.92.7-2.7-2.5-2.52.4-2.8-2.5-2.7-2.6-2.8-2.82.82.8-2.22.71.6
Patch foraging total patch changes 18 sec0.50.71.10.8-0.90.90.9-0.9-0.80.7-0.7-0.9-0.90.7-0.8-0.8-0.7-0.6-1.1-0.90.80.8-0.90.70.5
Patch foraging total patch changes 24 sec1.61.93.21.3-1.41.51.5-1.5-1.51.2-1.2-1.3-1.31.8-1.4-1.3-1.3-0.8-1.3-1.41.51.5-1.51.21.5
Patch foraging total patch changes 6 sec2.43.55.02.0-1.91.91.9-1.9-1.91.9-1.8-2.0-2.01.4-2.0-2.0-2.1-2.0-2.2-1.81.81.8-1.91.41.2
Patch foraging time to switch 0 sec0.10.10.30.3-0.30.30.4-0.3-0.40.4-0.4-0.4-0.40.2-0.4-0.2-0.3-0.4-0.5-0.40.30.3-0.10.6-0.0
Patch foraging water rate 0 sec0.10.10.50.3-0.30.30.2-0.3-0.40.3-0.3-0.5-0.5-0.1-0.4-0.5-0.4-0.4-0.4-0.30.40.4-0.70.00.3
Patch foraging water rate 12 sec0.10.21.3-0.20.1-0.1-0.10.10.2-0.30.30.50.5-0.50.70.31.00.71.10.0-0.1-0.1-0.4-0.30.3
Patch foraging water rate 18 sec0.50.71.30.6-0.80.80.9-0.9-1.00.8-0.8-0.5-0.50.9-0.9-0.7-0.9-0.7-0.5-0.81.01.0-0.51.21.1
Patch foraging water rate 24 sec0.81.11.81.0-1.00.90.9-0.9-1.21.1-1.1-1.3-1.30.6-1.1-1.1-1.2-1.4-1.0-0.81.11.1-0.60.80.6
Patch foraging water rate 6 sec1.82.63.31.6-1.71.71.7-1.7-1.61.6-1.6-1.7-1.71.0-1.6-1.7-1.7-1.6-1.2-1.71.81.8-1.31.41.6
Seeking ratio, delayed vs. immediate footshock0.40.41.60.9-0.70.70.6-0.6-0.60.7-0.7-0.6-0.6-0.1-0.1-0.30.30.40.9-0.40.60.6-1.3-0.71.1
Distance traveled before self-admin0.10.11.3-0.20.1-0.1-0.10.1-0.0-0.10.0-0.2-0.2-0.60.30.11.1-0.10.9-0.0-0.3-0.3-0.00.40.3
Distance traveled after self-admin1.31.53.7-1.31.2-1.3-1.21.21.1-1.31.30.90.9-1.71.20.81.00.60.91.1-1.9-1.91.1-0.7-0.6
Extensor digitorum longus weight9.537.541.1-6.26.4-6.3-6.46.46.3-6.36.36.26.2-5.76.46.06.16.36.26.2-6.4-6.45.6-5.4-4.7
Bone: elastic displacement0.00.00.50.10.0-0.0-0.10.1-0.10.0-0.00.00.00.10.10.2-0.00.1-0.10.1-0.0-0.0-0.2-0.2-0.7
Bone: elastic work0.10.10.30.1-0.30.30.3-0.3-0.50.3-0.3-0.3-0.30.0-0.4-0.0-0.3-0.2-0.3-0.20.50.5-0.30.60.5
Bone: endosteal estimation2.14.77.5-2.52.4-2.4-2.32.32.2-2.22.11.91.9-2.42.12.22.21.51.92.1-2.0-2.02.7-0.6-2.5
Bone: endosteal perimeter1.32.74.8-1.81.8-1.8-1.81.81.7-1.61.61.51.5-2.11.71.51.71.11.61.6-1.6-1.61.8-0.8-2.2
Epididymis fat weight0.10.21.3-0.50.3-0.3-0.30.30.2-0.30.20.30.3-1.10.40.80.40.70.70.0-0.2-0.20.20.3-0.6
Delta time in closed arm before/after self-admin3.43.34.5-2.12.1-2.1-2.12.01.9-1.91.92.02.0-1.91.52.11.02.10.92.0-1.7-1.71.7-1.5-0.8
Delta time in open arm before/after self-admin0.10.10.60.1-0.0-0.0-0.0-0.0-0.10.1-0.1-0.0-0.00.50.1-0.20.4-0.10.80.2-0.1-0.10.0-0.20.4
Diff in mean of infusions in LGA sessions0.20.20.9-0.2-0.10.10.1-0.1-0.2-0.10.10.50.5-0.90.40.70.70.80.6-0.2-0.7-0.7-0.60.20.2
Delay discount exponential model param0.20.20.5-0.30.3-0.3-0.40.40.2-0.30.30.20.2-0.70.50.60.70.60.50.3-0.3-0.30.10.0-0.5
Extinction: sum of active levers before priming1.71.72.6-1.61.5-1.4-1.41.41.4-1.41.41.61.6-0.91.21.21.01.01.21.4-1.3-1.31.3-0.7-0.6
Active lever presses in extinction session 61.61.56.50.6-1.11.11.3-1.3-1.11.2-1.2-1.1-1.10.5-1.4-0.9-0.8-1.2-1.0-1.31.41.4-1.12.61.3
Bone: final force0.50.82.80.5-0.70.80.9-0.9-0.90.8-0.8-0.9-0.91.4-1.0-0.5-0.7-0.9-0.8-0.81.11.1-0.21.70.6
Bone: final moment0.30.62.30.3-0.50.60.7-0.7-0.70.6-0.6-0.7-0.71.3-0.8-0.3-0.6-0.8-0.7-0.60.90.9-0.01.50.4
Food consumed during 24 hour testing period0.80.91.4-1.01.0-1.0-1.01.10.7-1.01.01.01.0-1.01.11.01.10.70.81.0-0.8-0.81.1-0.7-1.2
Glucose0.10.11.10.2-0.20.20.3-0.3-0.30.3-0.3-0.2-0.21.1-0.40.1-0.1-0.00.20.00.10.10.30.40.3
Heart weight3.44.86.6-2.22.4-2.4-2.42.42.2-2.01.92.02.0-2.31.92.61.62.21.82.6-2.2-2.22.3-2.0-2.1
Delay discount hyperbolic model param0.30.30.8-0.50.5-0.5-0.50.50.3-0.40.40.30.3-0.90.60.70.80.70.60.4-0.4-0.40.3-0.1-0.6
Intermittent access intake day 1-15 change0.70.71.40.7-0.90.80.8-0.9-1.00.8-0.8-0.6-0.60.2-0.8-0.9-0.9-0.8-1.0-0.91.01.0-0.80.51.2
Intermittent access intake escalation0.70.71.80.7-0.90.80.9-0.9-1.00.8-0.8-0.5-0.50.1-0.8-0.9-1.0-0.8-0.9-0.91.01.0-0.90.61.3
Intermittent access intake escalation 20.10.10.20.0-0.10.10.1-0.2-0.40.1-0.10.20.2-0.3-0.2-0.3-0.5-0.3-0.2-0.20.40.4-0.10.20.3
Intermitt. access day 1 inactive lever presses3.23.46.51.5-1.61.61.7-1.7-1.71.8-1.8-1.6-1.60.6-2.2-2.4-2.5-2.2-2.3-1.61.81.8-1.61.52.3
Intermitt. access day 15 inactive lever presses5.15.58.82.4-2.42.42.4-2.4-2.42.4-2.4-2.1-2.12.0-2.6-2.5-3.0-2.4-2.7-2.42.32.3-2.31.61.8
Intermitt. access escalation Index2.01.82.7-1.71.4-1.4-1.41.31.5-1.61.61.41.4-0.71.50.81.41.01.31.6-1.5-1.51.1-0.90.0
Intermittent access day 1 total infusions0.20.20.50.5-0.50.50.5-0.4-0.70.4-0.4-0.7-0.70.3-0.1-0.10.3-0.2-0.0-0.40.50.5-0.20.5-0.0
Intermittent access day 15 total infusions0.80.92.00.9-1.01.01.0-1.0-1.20.9-0.9-0.9-0.90.4-0.8-0.9-0.6-0.8-0.8-0.91.11.1-0.90.51.4
Intermittent access terminal intake (last 3 days)0.90.91.61.0-1.01.01.0-1.0-1.21.0-1.0-1.0-1.00.4-0.8-1.1-0.7-1.0-0.8-0.91.21.2-0.80.71.0
Intermittent access total infusions0.30.30.70.5-0.60.50.6-0.6-0.80.5-0.5-0.7-0.7-0.0-0.2-0.40.1-0.4-0.2-0.50.80.8-0.40.40.7
Intermittent access day 1 locomotion0.20.20.60.6-0.50.50.4-0.4-0.50.5-0.5-0.8-0.80.6-0.20.1-0.10.0-0.3-0.40.40.4-0.30.2-0.6
Intermittent access day 15 total locomotion0.40.41.40.8-0.60.60.5-0.4-0.70.6-0.6-0.7-0.70.8-0.30.3-0.5-0.1-0.8-0.60.80.80.00.4-1.2
Intermittent access total locomotion0.70.81.31.2-1.01.00.9-0.9-1.00.9-0.9-1.1-1.10.9-0.6-0.4-0.6-0.5-0.9-1.11.01.0-0.70.5-0.2
Intermittent access standard deviation2.52.74.31.7-1.71.71.7-1.7-2.01.6-1.6-1.5-1.50.3-1.4-1.8-1.5-1.6-1.6-1.82.12.1-1.90.91.6
Left kidney weight0.92.56.4-1.81.6-1.7-1.61.51.9-1.71.71.61.6-2.51.30.91.31.31.01.7-2.0-2.00.6-1.60.4
Right kidney weight0.10.31.3-0.90.6-0.6-0.50.40.6-0.60.60.50.5-1.10.30.40.40.50.30.5-0.6-0.60.50.20.5
Cocaine induced anxiety1.72.03.7-1.91.6-1.7-1.51.51.5-1.61.61.51.5-1.61.21.01.01.00.91.5-1.5-1.51.7-0.3-0.6
Post-drug Anxiety0.20.20.4-0.60.5-0.5-0.40.40.5-0.50.50.40.4-0.20.30.40.50.30.40.5-0.5-0.50.5-0.00.2
Baseline Anxiety1.21.33.61.6-1.41.41.2-1.2-1.11.2-1.2-1.2-1.21.9-0.9-0.7-0.8-0.7-0.6-1.21.11.1-1.40.10.5
Tail length0.20.62.9-0.70.6-0.6-0.60.60.7-0.80.81.01.0-1.70.80.50.60.90.70.4-0.7-0.70.7-0.8-0.2
Length with tail2.59.118.3-3.33.1-3.1-3.13.03.1-3.13.13.23.2-4.33.12.93.13.33.02.8-2.8-2.82.1-2.3-1.5
Length without tail3.47.512.0-3.32.9-2.9-2.82.72.8-2.82.82.72.7-3.52.83.03.22.93.02.7-2.4-2.41.9-1.4-1.5
Times rat made contact with spout1.01.12.21.0-0.90.90.9-0.9-1.21.1-1.1-1.1-1.11.3-1.1-0.8-1.5-1.4-1.3-0.91.21.2-0.41.0-0.2
Lifetime Intake0.40.41.10.6-0.70.60.7-0.7-0.90.6-0.6-0.8-0.8-0.1-0.4-0.6-0.1-0.4-0.3-0.60.80.8-0.60.41.1
Liver weight, left0.00.00.20.1-0.20.20.2-0.2-0.30.1-0.1-0.0-0.0-0.4-0.10.00.10.10.0-0.30.30.3-0.10.30.4
Liver weight, right0.61.14.50.7-1.01.01.1-1.2-1.00.9-1.0-0.9-0.90.1-1.1-1.3-0.7-0.9-0.9-1.00.90.9-0.61.12.1
Locomotor activity0.50.82.40.6-0.90.90.9-0.9-1.20.8-0.8-0.9-0.91.1-0.8-0.5-0.9-0.8-0.5-1.01.11.1-0.51.60.4
Locomotor testing distance2.13.64.81.8-2.02.02.0-2.0-2.11.7-1.7-2.0-2.02.2-1.8-1.7-1.7-2.0-1.7-2.12.02.0-1.91.81.1
Locomotor testing rearing6.610.212.73.4-3.43.43.4-3.4-3.13.1-3.1-3.4-3.42.8-3.2-3.6-3.1-3.5-3.3-3.33.13.1-3.02.12.7
Locomotion in novel chamber5.16.28.42.7-2.82.82.8-2.8-2.62.6-2.7-2.9-2.92.9-2.5-1.9-1.9-1.8-1.7-2.52.32.3-2.22.32.4
Locomotion in novel chamber post-restriction0.91.12.80.9-1.11.01.0-1.0-1.21.2-1.2-1.0-1.01.0-1.1-0.6-0.8-1.1-1.1-1.21.11.1-0.51.7-0.0
Fecal boli incidents, locomotor time 10.40.52.0-0.50.7-0.7-0.70.80.7-0.50.40.10.1-0.10.71.10.30.80.70.6-0.7-0.71.1-0.4-1.4
Change in fecal boli incidents, locomotor task0.10.10.3-0.20.1-0.1-0.00.00.0-0.20.30.50.50.20.20.40.50.40.30.3-0.2-0.20.0-0.1-0.1
Time >=10cm from walls, locomotor time 10.20.21.20.6-0.50.50.5-0.4-0.20.3-0.4-0.2-0.20.9-0.3-0.2-0.20.1-0.3-0.30.10.1-1.1-0.30.3
Bouts of movement, locomotor time 10.40.41.1-1.00.7-0.7-0.70.60.6-1.01.00.70.7-1.00.60.10.30.5-0.00.4-0.4-0.40.4-0.20.1
Total resting periods, locomotor time 10.91.02.1-1.41.1-1.2-1.11.11.0-1.41.51.11.1-1.21.00.80.61.00.40.8-0.7-0.71.1-0.4-0.6
Rest time, locomotor task time 10.10.20.8-0.10.0-0.0-0.00.0-0.10.00.0-0.2-0.2-0.1-0.2-0.4-0.9-0.6-0.8-0.20.20.20.80.5-0.5
Distance moved, locomotor task time 10.10.10.40.3-0.30.30.3-0.3-0.20.4-0.5-0.5-0.50.5-0.4-0.00.40.00.2-0.10.10.1-0.6-0.00.7
Vertical activity count, locomotor time 10.40.41.7-0.30.3-0.3-0.30.30.1-0.30.20.50.5-0.10.51.21.01.31.30.5-0.4-0.40.3-0.4-0.3
Time >=10cm from walls, locomotor time 20.90.92.61.0-1.11.21.2-1.2-0.90.9-0.9-0.8-0.81.6-0.5-0.10.50.20.2-1.11.21.2-1.41.10.4
Bouts of movement, locomotor time 20.40.41.70.4-0.60.60.6-0.7-0.20.3-0.3-0.3-0.3-0.0-0.6-1.2-0.5-0.4-0.7-0.70.40.4-1.30.21.3
Total resting periods, locomotor time 20.30.31.70.3-0.40.40.5-0.5-0.00.1-0.1-0.1-0.1-0.2-0.4-1.0-0.5-0.2-0.5-0.60.30.3-1.30.01.3
Rest time, locomotor task time 20.80.91.3-1.11.0-1.0-1.01.01.0-1.11.11.01.0-1.21.01.00.61.00.70.8-0.8-0.81.2-0.6-0.6
Distance moved, locomotor task time 20.10.10.3-0.30.3-0.3-0.20.20.40.1-0.1-0.0-0.00.1-0.20.40.10.30.10.5-0.4-0.40.30.0-0.1
Vertical activity count, locomotor time 20.40.41.2-0.50.5-0.5-0.50.50.5-0.40.40.60.6-0.20.41.00.51.00.80.8-0.8-0.81.1-0.6-0.6
Light reinforcement 13.36.08.72.4-2.52.52.5-2.5-2.62.4-2.4-2.5-2.51.7-2.7-2.6-2.9-2.7-3.0-2.52.52.5-1.92.11.9
Light reinforcement 20.70.93.20.7-0.70.70.8-0.8-1.01.0-1.0-0.9-0.90.9-1.4-0.6-1.8-1.0-1.4-0.60.90.9-0.11.40.2
Bone: marrow area2.04.37.1-2.52.4-2.3-2.22.22.1-2.12.11.91.9-2.32.02.12.11.51.82.1-2.0-2.02.7-0.6-2.4
Bone: maximum diameter0.00.10.30.1-0.20.20.2-0.2-0.10.2-0.2-0.2-0.20.1-0.2-0.3-0.1-0.4-0.1-0.30.20.2-0.20.60.0
Bone: maximum force0.00.10.4-0.50.3-0.3-0.20.20.2-0.20.20.10.10.3-0.00.30.10.00.10.2-0.1-0.10.60.6-0.1
Bone: maximum moment0.10.10.5-0.60.5-0.5-0.40.40.4-0.40.40.30.30.20.20.50.20.10.20.5-0.3-0.30.70.4-0.3
Mean time between licks in bursts1.31.84.4-1.41.4-1.4-1.41.51.4-1.31.31.21.2-1.31.41.21.40.90.91.3-1.4-1.41.4-0.8-2.1
Mean num. licks in bursts0.20.20.70.6-0.40.30.3-0.3-0.50.5-0.5-0.5-0.50.0-0.5-0.5-0.6-0.7-0.8-0.20.40.4-0.3-0.20.1
Cd content in liver0.20.20.50.4-0.40.30.4-0.4-0.30.4-0.3-0.4-0.40.2-0.6-0.5-0.6-0.6-0.7-0.30.60.6-0.30.20.6
Co content in liver0.50.61.7-0.60.8-0.8-0.90.90.8-0.60.60.70.7-1.30.70.70.50.80.60.9-0.7-0.70.6-1.1-0.6
Cu content in liver0.10.11.10.2-0.10.10.1-0.1-0.10.1-0.1-0.1-0.1-1.0-0.1-0.3-0.20.0-0.2-0.10.30.3-0.6-0.50.4
Fe content in liver0.91.11.7-1.31.2-1.1-1.11.01.0-1.11.11.11.1-1.30.91.11.01.10.91.0-1.1-1.11.2-0.4-0.4
K content in liver1.61.63.21.1-1.41.41.4-1.5-1.41.1-1.1-1.1-1.10.7-1.2-1.5-1.0-1.1-1.0-1.41.21.2-1.21.21.8
Mg content in liver1.51.55.01.3-1.41.41.4-1.4-1.20.9-0.9-0.8-0.80.8-1.0-1.8-0.7-1.0-0.7-1.31.11.1-1.90.22.2
Mn content in liver2.73.14.71.9-1.91.91.9-2.0-1.81.6-1.6-1.5-1.50.8-1.7-2.1-1.7-1.7-1.6-1.91.81.8-2.21.12.0
Na content in liver0.30.32.00.1-0.50.50.6-0.6-0.70.4-0.4-0.4-0.40.5-0.6-0.4-0.3-0.5-0.4-0.70.60.60.11.40.8
Rb content in liver1.51.92.41.5-1.51.41.4-1.4-1.41.4-1.4-1.5-1.51.2-1.4-1.5-1.4-1.5-1.5-1.31.31.3-1.40.81.1
Se content in liver6.07.410.42.8-2.92.92.9-2.9-2.82.7-2.7-2.7-2.71.8-2.7-3.2-2.5-2.8-2.5-2.92.72.7-2.72.12.9
Sr content in liver0.10.10.70.5-0.40.40.3-0.3-0.30.3-0.3-0.3-0.3-0.4-0.0-0.3-0.1-0.20.0-0.40.30.3-0.8-0.20.3
Zn content in liver3.53.94.92.1-2.02.02.0-2.0-2.12.2-2.2-2.1-2.11.3-2.0-2.1-2.0-2.2-2.1-1.92.12.1-1.61.61.1
Bone: minimum diameter0.50.91.3-1.11.0-1.0-1.01.01.1-0.90.90.90.9-1.00.81.00.90.71.11.0-1.1-1.10.8-0.3-0.8
Time in familiar zone, hab. session 10.40.42.00.1-0.20.20.4-0.4-0.50.6-0.7-0.7-0.70.6-0.8-0.2-0.7-0.8-0.6-0.30.50.50.71.40.1
Time in novel zone, hab. session 10.70.72.71.2-0.90.90.7-0.7-0.60.7-0.7-0.6-0.60.9-0.7-0.9-1.0-0.5-1.1-0.70.60.6-1.7-0.60.5
Total zone transitions, hab. session 11.62.23.2-1.51.6-1.6-1.61.61.6-1.41.41.51.5-1.81.51.51.11.51.41.7-1.3-1.31.3-1.5-1.1
Total locomotion distance, hab. session 10.00.00.20.1-0.0-0.0-0.00.0-0.20.1-0.1-0.1-0.1-0.2-0.10.1-0.20.1-0.20.20.30.3-0.3-0.40.4
Locomotion velocity, hab. session 10.20.30.9-0.60.5-0.6-0.50.50.4-0.50.50.50.5-1.00.60.50.70.60.50.6-0.4-0.40.2-0.70.2
Time in familiar zone, hab. session 20.60.61.10.6-0.70.70.8-0.8-0.80.9-0.9-0.8-0.80.6-1.0-0.8-0.9-0.9-0.8-0.60.90.9-0.11.01.0
Time in novel zone, hab. session 20.20.21.00.6-0.50.50.4-0.4-0.30.4-0.4-0.4-0.40.3-0.3-0.5-0.4-0.3-0.5-0.60.20.2-1.0-0.0-0.0
Total zone transitions, hab. session 21.11.42.6-1.11.3-1.2-1.31.31.1-1.11.11.21.2-0.91.11.50.71.31.21.3-0.9-0.91.3-0.9-1.6
Total locomotion distance, hab. session 20.30.41.5-0.60.7-0.7-0.70.70.3-0.40.40.40.4-0.40.41.10.10.60.30.7-0.3-0.30.9-0.2-1.2
Locomotion velocity, hab. session 20.50.71.7-0.90.9-0.9-0.90.90.5-0.60.60.70.7-0.70.71.30.50.90.60.9-0.5-0.51.1-0.4-1.3
Novel to familiar place preference ratio1.01.11.8-1.00.9-0.9-0.90.81.2-1.21.21.21.2-1.11.10.51.31.11.20.8-1.2-1.20.3-1.20.3
Novelty place preference0.90.91.7-0.80.8-0.7-0.80.71.2-1.11.11.11.1-0.91.10.31.31.01.20.7-1.2-1.20.1-1.30.4
Time in novel zone, NPP test0.40.40.9-0.40.4-0.3-0.40.30.8-0.70.70.70.7-0.40.7-0.00.90.60.70.3-0.8-0.8-0.2-0.90.7
Total zone transitions, NPP test0.71.03.5-1.01.1-1.1-1.01.10.8-0.70.70.80.8-0.70.81.40.50.81.01.0-0.4-0.41.7-0.0-1.9
Total locomotion distance, NPP test0.10.21.5-0.20.3-0.3-0.30.3-0.10.1-0.1-0.1-0.10.0-0.10.6-0.30.0-0.20.40.30.30.80.4-1.2
Locomotion velocity, NPP test0.40.62.6-0.80.9-0.9-0.90.90.5-0.50.50.50.5-0.60.61.20.30.60.40.9-0.3-0.31.2-0.2-1.6
Intraocular pressure3.14.36.6-1.82.1-2.1-2.22.32.3-2.02.01.71.7-1.52.22.32.01.81.92.0-2.2-2.22.5-1.9-2.6
Delta distance traveled before/after self-admin1.41.52.1-1.21.3-1.3-1.31.31.3-1.41.51.41.4-1.31.21.10.41.20.71.2-1.4-1.41.3-1.3-0.8
Delta ambulatory time before/after self-admin1.11.22.4-1.21.2-1.2-1.21.11.3-1.31.31.31.3-0.70.80.7-0.20.70.11.1-1.4-1.41.6-0.8-0.9
Parametrial fat weight1.93.75.51.6-1.91.81.9-1.9-2.11.9-2.0-1.9-1.90.7-2.0-1.9-1.7-2.2-2.1-2.22.32.3-1.42.31.4
Pavlov. Cond. lever latency2.73.46.0-1.61.7-1.8-1.81.81.9-2.12.11.91.9-2.02.11.42.22.01.91.9-1.7-1.71.2-2.4-0.7
Pavlov. Cond. magazine entry latency10.012.814.73.5-3.73.63.7-3.7-3.73.8-3.8-3.7-3.73.7-3.8-3.4-3.7-3.7-3.5-3.63.63.6-3.03.52.5
Pavlov. Cond. change in total contacts9.510.211.83.4-3.33.33.3-3.3-3.13.4-3.3-3.2-3.23.1-3.4-3.4-3.4-3.4-3.2-3.12.92.9-3.32.22.8
Pavlov. Cond. index score7.910.011.93.1-3.23.23.2-3.2-3.33.4-3.4-3.3-3.33.4-3.5-2.7-3.4-3.3-3.2-3.23.23.2-2.43.41.7
Pavlov. Cond. latency score5.97.49.72.6-2.72.72.7-2.7-2.83.0-3.0-2.9-2.93.1-3.0-2.3-3.0-2.9-2.7-2.72.72.7-1.93.11.4
Pavlov. Cond. lever contacts2.22.64.91.4-1.51.51.5-1.5-1.71.8-1.8-1.7-1.71.8-1.8-1.1-1.9-1.8-1.6-1.61.51.5-0.92.20.3
Pavlov. Cond. magazine entry number12.415.517.5-4.04.0-4.0-4.04.04.0-4.24.24.14.1-4.24.23.74.14.24.03.8-4.0-4.03.3-3.5-2.6
Pavlov. Cond. intertrial magazine entries1.41.72.6-1.21.3-1.3-1.31.31.4-1.41.51.51.5-1.31.41.01.41.61.41.2-1.4-1.40.8-1.5-0.6
Pavlov. Cond. lever-magazine prob. diff.8.911.013.03.3-3.33.33.4-3.3-3.43.6-3.6-3.5-3.53.6-3.6-2.9-3.5-3.5-3.3-3.33.33.3-2.63.41.8
Pavlov. Cond. response bias9.411.413.13.4-3.43.43.4-3.4-3.53.6-3.6-3.5-3.53.5-3.6-3.2-3.6-3.5-3.4-3.33.33.3-3.03.12.4
Pavlov. Cond. lever latency0.40.50.7-0.60.7-0.7-0.70.70.8-0.80.80.80.8-0.60.70.50.60.80.80.7-0.8-0.80.7-0.7-0.3
Pavlov. Cond. magazine entry latency0.10.10.6-0.30.2-0.3-0.30.3-0.1-0.30.30.30.3-0.00.30.80.50.50.40.20.00.00.4-0.1-0.4
Pavlov. Cond. change in total contacts0.70.91.41.2-1.11.11.0-1.0-1.01.1-1.1-1.1-1.10.8-0.9-0.8-0.8-1.0-1.0-1.00.80.8-1.00.50.4
Pavlov. Cond. index score0.20.20.40.4-0.40.40.4-0.4-0.60.5-0.5-0.6-0.60.6-0.5-0.0-0.4-0.5-0.6-0.40.50.5-0.10.6-0.2
Pavlov. Cond. latency score0.10.10.20.2-0.30.30.2-0.2-0.50.3-0.4-0.4-0.40.5-0.30.1-0.2-0.3-0.4-0.30.40.40.00.4-0.4
Pavlov. Cond. lever contacts0.81.01.50.9-1.01.01.0-1.0-1.21.1-1.1-1.1-1.11.1-1.1-0.6-0.9-1.2-1.2-1.11.11.1-0.81.20.4
Pavlov. Cond. magazine entry number0.00.00.2-0.00.1-0.1-0.10.10.3-0.20.20.20.2-0.50.3-0.30.2-0.00.30.1-0.3-0.3-0.0-0.20.0
Pavlov. Cond. intertrial magazine entries1.52.03.5-1.11.2-1.2-1.31.31.6-1.51.51.51.5-1.61.80.91.71.51.61.2-1.6-1.60.3-1.9-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.2-0.30.30.3-0.2-0.50.4-0.4-0.4-0.40.4-0.40.1-0.2-0.3-0.5-0.30.40.4-0.00.4-0.2
Pavlov. Cond. response bias1.11.52.11.1-1.21.21.2-1.2-1.41.3-1.3-1.3-1.31.2-1.3-0.8-1.1-1.3-1.3-1.31.41.4-1.01.40.6
Time in closed arm before self-admin1.31.54.21.4-1.11.11.1-1.1-0.91.2-1.1-1.5-1.50.9-1.2-2.0-1.5-2.1-1.6-0.90.20.2-0.50.20.9
Time in closed arm after self-admin0.50.52.0-0.50.6-0.6-0.60.60.8-0.70.70.30.3-1.00.4-0.20.30.1-0.10.7-1.0-1.00.4-1.40.8
Time in open arm before self-admin2.22.36.2-1.61.4-1.3-1.31.31.2-1.51.51.81.8-2.01.82.22.02.51.81.2-0.9-0.90.7-0.7-0.9
Time in open arm after self-admin0.70.72.6-0.70.7-0.7-0.70.70.4-0.60.61.01.0-0.61.01.21.31.21.60.7-0.4-0.40.5-0.5-0.8
Bone: periosteal estimation0.30.51.0-1.00.9-0.8-0.80.80.8-0.70.70.50.5-0.70.60.80.80.30.60.7-0.6-0.61.00.2-0.9
Bone: periosteal perimeter0.71.12.2-1.31.2-1.2-1.21.21.1-1.01.00.90.9-1.11.01.11.10.61.01.1-0.9-0.91.3-0.2-1.5
Bone: post-yield work1.52.02.5-1.61.6-1.5-1.51.51.6-1.51.51.61.6-1.21.41.41.21.21.21.5-1.4-1.41.4-1.1-1.0
Progressive ratio test 1 active lever presses0.60.61.30.9-0.80.80.8-0.8-0.70.7-0.7-1.1-1.11.1-0.7-0.9-0.5-0.8-0.7-0.70.70.7-0.60.40.7
Progressive ratio test 1 breakpoint0.50.51.10.7-0.70.70.7-0.7-0.60.6-0.6-1.0-1.01.0-0.6-0.8-0.5-0.7-0.7-0.60.60.6-0.50.40.8
Progressive ratio test 1 inactive lever presses2.12.33.91.5-1.51.51.5-1.5-1.51.4-1.4-1.5-1.50.9-1.5-2.0-1.7-1.8-1.9-1.41.41.4-1.60.91.7
Progressive ratio test 2 active lever presses1.21.32.11.4-1.41.31.3-1.3-1.41.2-1.2-1.3-1.31.1-0.7-0.9-0.5-1.1-0.6-1.31.31.3-1.00.70.4
Progressive ratio test 2 breakpoint0.81.01.51.2-1.21.11.1-1.1-1.21.0-1.0-1.1-1.11.1-0.6-0.8-0.3-0.9-0.4-1.11.11.1-0.90.60.4
Progressive ratio test 2 inactive lever presses0.60.71.41.0-0.90.90.8-0.8-1.20.9-1.0-1.0-1.00.3-0.6-0.6-0.5-0.8-0.7-0.91.11.1-0.80.50.1
Incentive Sensitization - Responses1.31.32.21.5-1.31.31.2-1.1-1.51.3-1.3-1.2-1.21.2-0.7-0.6-0.4-1.1-0.6-1.31.41.4-0.80.9-0.8
Incentive Sensitization - Breakpoint1.21.22.11.4-1.21.21.1-1.1-1.41.3-1.3-1.2-1.21.2-0.7-0.6-0.4-1.1-0.6-1.31.41.4-0.70.9-0.7
Sum of active levers in priming session hrs 5-60.50.51.60.4-0.60.60.7-0.7-0.60.8-0.8-0.5-0.50.5-0.9-0.6-0.8-0.4-0.5-0.50.80.8-0.50.91.3
Progressive ratio0.10.10.70.2-0.30.40.4-0.4-0.20.3-0.3-0.5-0.50.0-0.5-0.1-0.20.20.2-0.50.10.10.10.80.1
Food seeking constrained by brief footshock0.30.41.40.4-0.50.50.5-0.6-0.50.3-0.3-0.4-0.40.4-0.5-1.1-0.7-1.2-1.0-0.60.50.50.11.0-0.1
Seeking ratio, punishment vs. effort0.10.10.60.00.1-0.1-0.10.10.0-0.20.20.20.20.50.2-0.40.1-0.8-0.50.20.10.1-0.0-0.4-0.3
Retroperitoneal fat weight0.00.10.5-0.40.4-0.4-0.30.30.2-0.20.2-0.0-0.0-0.7-0.10.1-0.1-0.1-0.00.4-0.2-0.20.60.1-0.0
Reaction time number correct0.81.23.2-1.11.0-1.0-1.01.00.7-1.00.90.90.9-0.91.21.71.81.41.51.2-0.6-0.60.8-0.5-0.8
Reaction time mean minus median0.40.51.6-0.50.6-0.6-0.70.70.8-0.60.60.80.8-0.30.61.10.30.80.20.5-0.9-0.90.8-0.7-1.3
Reaction time mean minus median AUC0.10.10.7-0.00.1-0.1-0.20.20.2-0.10.10.20.20.50.00.6-0.10.2-0.30.2-0.2-0.20.3-0.3-0.8
Reaction time num false alarms0.50.71.80.6-0.60.70.7-0.7-0.90.7-0.7-1.0-1.01.0-0.8-0.4-0.6-0.9-0.8-0.81.11.1-0.01.3-0.1
Reaction time num false alarms AUC0.40.51.60.4-0.50.60.6-0.6-0.80.6-0.6-0.8-0.80.9-0.6-0.2-0.5-0.7-0.7-0.80.90.9-0.01.3-0.4
Reaction time trials correct on left0.81.23.2-1.11.0-1.0-1.01.00.7-1.00.90.90.9-0.91.21.71.81.41.51.2-0.6-0.60.8-0.5-0.8
Reaction time trials on left0.81.13.0-1.11.0-1.0-1.01.00.6-0.90.90.80.8-0.91.11.71.71.41.51.1-0.6-0.60.8-0.5-0.8
Reaction time mean0.20.30.60.7-0.70.60.6-0.6-0.50.5-0.5-0.2-0.20.2-0.4-0.7-0.5-0.5-0.8-0.80.40.4-0.6-0.10.8
Reaction time mean AUC0.20.30.90.7-0.70.60.6-0.6-0.50.5-0.5-0.2-0.20.1-0.5-0.7-0.6-0.4-0.8-0.70.40.4-0.7-0.10.9
Median of all reaction times1.11.52.31.4-1.41.31.3-1.3-1.31.2-1.2-0.9-0.90.8-1.0-1.5-1.0-1.2-1.3-1.51.21.2-1.20.41.5
Reaction time omissions1.11.52.51.3-1.31.31.3-1.3-1.41.3-1.3-1.2-1.21.1-1.3-1.0-1.6-1.3-1.4-1.31.41.4-0.81.20.5
Reaction time false alarm rate0.81.21.90.9-1.01.01.0-1.0-1.01.0-1.0-1.2-1.21.2-1.2-1.1-1.3-1.3-1.3-1.21.11.1-0.51.40.2
Reaction time premature initiation rate0.50.74.80.5-0.90.90.9-1.0-0.90.6-0.6-0.4-0.40.4-0.7-0.7-0.5-0.2-0.5-1.00.90.9-0.70.92.2
Reaction time premature initiations0.10.21.9-0.3-0.10.00.1-0.2-0.3-0.20.10.40.4-0.30.20.50.70.70.5-0.00.30.3-0.00.31.4
Std. dev. reaction times0.00.00.30.00.0-0.0-0.10.10.20.0-0.00.30.30.10.00.4-0.10.2-0.4-0.1-0.3-0.30.1-0.2-0.5
Reaction time trials completed0.81.13.0-1.11.0-1.0-1.01.00.6-0.90.90.80.8-0.91.11.71.71.41.51.1-0.6-0.60.8-0.5-0.8
Reaction time trials AUC0.71.03.0-1.00.9-0.9-1.01.00.6-0.90.90.80.8-0.71.11.61.71.41.51.1-0.6-0.60.7-0.6-0.8
Run reversals in cocaine runway, females2.52.45.0-1.41.4-1.4-1.51.41.3-1.51.51.71.7-1.51.81.42.21.82.01.7-1.3-1.30.5-2.20.5
Run reversals in cocaine runway, males0.50.51.00.8-0.70.70.7-0.7-0.80.8-0.9-0.7-0.71.0-0.6-0.80.0-0.8-0.2-0.50.80.8-0.50.40.2
Latency to leave start box in cocaine runway1.41.62.9-1.31.3-1.3-1.31.31.1-1.11.01.01.0-1.71.21.41.61.51.61.5-1.1-1.10.5-1.2-0.3
Latency to leave start box in cocaine runway, F1.61.74.2-1.41.3-1.3-1.31.31.1-1.21.21.11.1-1.61.41.42.11.62.01.4-1.1-1.10.5-1.00.0
Latency to leave start box in cocaine runway, M0.40.41.20.6-0.40.40.4-0.4-0.40.7-0.7-0.7-0.7-0.3-0.8-0.6-1.1-0.6-1.1-0.20.40.4-1.0-0.20.4
Std. dev. time between licks in bursts0.00.10.2-0.40.3-0.2-0.20.20.2-0.20.20.30.3-0.40.00.10.1-0.0-0.10.1-0.1-0.10.30.3-0.5
Total sessions with >9 infusions0.91.01.91.0-0.90.90.9-1.0-0.91.1-1.1-0.9-0.90.8-1.2-1.4-1.3-1.1-1.2-0.71.01.0-1.00.21.4
Short access day 1 total inactive lever presses2.62.94.31.8-1.71.71.7-1.7-2.11.9-1.9-1.7-1.71.1-1.9-1.5-2.1-1.3-1.9-1.51.91.9-1.41.21.2
Short access day 10 total inactive lever presses0.10.10.8-0.30.2-0.2-0.20.1-0.2-0.10.10.50.5-0.9-0.1-0.2-0.60.1-0.20.20.20.2-0.00.00.6
Short access day 1 total infusions1.21.33.71.0-1.01.01.1-1.1-1.11.1-1.1-1.4-1.40.2-1.1-1.6-1.1-1.1-0.9-0.81.11.1-1.20.51.9
Short access day 10 total infusions0.40.40.80.6-0.70.70.7-0.7-0.90.6-0.7-0.9-0.90.4-0.5-0.5-0.3-0.6-0.4-0.60.70.7-0.30.80.5
Short access total infusions0.60.62.80.7-0.80.70.8-0.8-0.90.7-0.7-0.8-0.8-0.1-0.6-1.0-0.4-0.6-0.4-0.70.80.8-0.90.31.7
Short access day 1 locomotion4.64.97.62.2-2.22.22.2-2.2-2.32.2-2.2-2.3-2.31.6-2.3-2.6-2.7-2.5-2.8-2.02.12.1-2.11.61.7
Short access day 10 total locomotion1.21.32.21.4-1.21.21.2-1.1-1.11.2-1.2-1.5-1.51.5-0.9-0.8-0.8-1.1-1.2-1.21.11.1-0.71.1-0.6
Short access total locomotion0.60.61.01.0-0.80.80.7-0.7-0.90.8-0.8-1.0-1.00.5-0.7-0.7-0.8-0.7-0.9-0.70.80.8-0.80.10.1
One hour access (0.3 mA shock)0.00.00.20.1-0.10.10.1-0.1-0.1-0.0-0.0-0.2-0.2-0.00.20.20.40.30.4-0.20.10.1-0.1-0.20.0
Compulsive drug intake0.40.42.5-0.30.5-0.5-0.60.70.6-0.50.50.60.6-0.40.70.50.70.70.60.6-0.7-0.70.0-1.6-0.7
One hour access (shock baseline)0.40.40.90.5-0.70.70.7-0.7-0.80.6-0.6-0.8-0.80.3-0.5-0.5-0.3-0.5-0.3-0.60.80.8-0.31.00.7
Social response proportion0.30.40.8-0.70.7-0.7-0.70.60.8-0.60.70.60.60.00.40.60.30.60.50.9-0.7-0.70.6-0.6-0.1
Social responses0.10.10.5-0.0-0.00.00.1-0.1-0.00.3-0.2-0.2-0.20.2-0.5-0.1-0.7-0.5-0.3-0.00.00.00.30.7-0.2
Social time0.20.32.5-0.50.4-0.4-0.40.4-0.0-0.20.20.20.2-0.10.20.80.2-0.10.10.20.20.21.00.8-1.6
Soleus weight0.10.32.2-0.60.4-0.3-0.20.20.2-0.30.30.30.31.30.00.6-0.00.10.10.2-0.3-0.31.51.0-0.7
Bone: stiffness0.00.00.3-0.30.1-0.10.0-0.10.1-0.10.1-0.0-0.00.3-0.1-0.00.2-0.10.10.10.10.10.40.50.6
Tibialis anterior weight1.55.27.6-2.62.5-2.5-2.42.42.4-2.32.32.32.3-2.02.22.22.22.22.22.3-2.5-2.52.8-1.3-1.5
Time to tail flick, vehicle, before self-admin0.20.22.40.2-0.0-0.0-0.10.2-0.20.3-0.3-0.1-0.10.5-0.20.3-0.4-0.3-0.60.00.20.20.1-0.1-1.6
Time to tail flick, vehicle, after self-admin0.10.10.80.1-0.10.10.1-0.10.00.2-0.2-0.2-0.20.3-0.10.4-0.30.1-0.2-0.30.20.20.20.5-0.9
Time to tail flick, test, before self-admin1.71.62.8-1.31.2-1.2-1.21.31.2-1.41.41.71.7-1.11.61.51.11.41.11.1-0.8-0.81.4-1.0-1.1
Time to tail flick, test, after self-admin0.20.21.30.3-0.10.10.00.0-0.40.6-0.6-0.6-0.60.3-0.60.4-0.8-0.3-0.70.00.10.10.30.6-1.1
Delta time to tail flick, vehicle, before/after SA0.20.21.70.1-0.40.40.4-0.4-0.30.2-0.2-0.3-0.30.5-0.3-0.2-0.4-0.4-0.3-0.50.50.50.21.30.0
Delta time to tail flick, test, before/after SA2.42.24.01.7-1.41.41.4-1.3-1.61.9-1.9-2.0-2.01.7-1.8-1.0-1.6-1.5-1.4-1.21.01.0-1.11.3-0.0
Tibia length1.74.77.9-2.72.4-2.4-2.32.32.1-2.22.22.22.2-1.41.92.62.12.11.92.4-2.2-2.22.8-0.9-1.7
Ambulatory time before self-admin0.10.11.1-0.20.2-0.2-0.20.20.0-0.20.1-0.1-0.1-0.80.50.01.0-0.20.80.1-0.1-0.1-0.0-0.00.1
Ambulatory time after self-admin2.12.34.8-1.81.7-1.8-1.71.61.5-1.61.71.21.2-2.21.40.80.70.40.71.5-2.2-2.22.0-0.8-1.2
Bone: tissue strength1.11.11.6-1.01.1-1.1-1.11.11.1-1.11.11.11.1-0.51.11.20.91.00.91.1-1.1-1.10.9-1.0-1.2
Total heroin consumption1.92.25.71.3-1.61.51.6-1.6-1.91.7-1.7-1.5-1.50.7-1.3-0.7-1.0-1.1-1.2-1.61.91.9-1.22.40.7
Bone: trabecular number5.48.59.62.7-2.92.93.0-3.0-3.02.9-2.9-3.0-3.03.0-3.1-2.9-3.0-2.9-3.1-2.93.03.0-2.03.12.3
Bone: trabecular spacing1.82.44.4-1.71.7-1.7-1.61.71.3-1.41.41.41.4-1.21.51.91.51.41.61.6-1.3-1.32.0-0.6-2.1
Bone: trabecular thickness0.20.20.50.4-0.30.30.3-0.3-0.30.5-0.5-0.4-0.40.3-0.5-0.4-0.7-0.5-0.7-0.30.40.4-0.20.40.1
Bone: trabecular tissue density0.10.11.30.4-0.10.10.0-0.00.2-0.10.20.20.20.10.3-0.30.30.30.00.1-0.2-0.2-0.9-1.10.4
Water consumed over 24 hours0.10.10.6-0.30.4-0.4-0.40.4-0.2-0.20.20.20.20.10.30.50.20.10.10.50.10.10.5-0.1-0.8
Number of responses in last shaping day0.80.81.80.9-0.80.80.8-0.8-0.81.0-1.0-0.8-0.8-0.0-1.0-1.0-1.0-0.8-1.0-0.80.80.8-1.30.11.1