Hub : Genes

Msl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Msl1 0.13 0.08 2.0e-05 0.07 0.07 0.06 0.08 2.1e-04 1.4e-04 3.6e-04 4.2e-05
2 NAcc isoform ratio NM_001107048.1 0.03 0.02 4.7e-06 0.03 0.04 0.03 0.03 1.6e-05 1.8e-06 5.7e-05 9.3e-06
3 IC alternative polyA XM_006247304.5 0.07 0.05 1.6e-03 0.04 0.06 0.04 0.04 5.6e-03 1.7e-03 1.3e-02 1.3e-02
4 IC alternative polyA NM_001107048.1 0.07 0.05 1.2e-03 0.05 0.06 0.04 0.04 4.3e-03 1.2e-03 9.9e-03 1.2e-02
5 Brain alternative polyA XM_006247304.5 0.12 0.09 1.1e-06 0.07 0.07 0.06 0.07 7.4e-07 5.1e-07 4.8e-06 8.2e-07
6 Adipose alternative polyA NM_001107048.1 0.02 0.02 3.1e-03 0.01 0 0 0 2.7e-02 2.0e-01 1.6e-01 2.9e-01
7 Adipose alternative polyA XM_006247304.5 0.02 0.02 2.2e-03 0.01 0 0 0 1.1e-02 1.2e-01 7.8e-02 7.9e-02
8 Adipose isoform ratio NM_001107048.1 0.03 0.02 1.1e-03 0.02 0.02 0.01 0.02 1.2e-03 5.3e-03 1.2e-02 2.4e-03
9 Adipose isoform ratio XM_006247304.5 0.03 0.02 1.1e-03 0.02 0.02 0.01 0.02 1.2e-03 5.9e-03 1.2e-02 3.2e-03
10 Brain alternative polyA NM_001107048.1 0.11 0.08 2.5e-06 0.06 0.06 0.06 0.06 1.4e-06 1.1e-06 4.2e-06 1.4e-06
11 NAcc isoform ratio XM_006247304.5 0.03 0.02 2.2e-06 0.04 0.04 0.03 0.04 3.1e-06 1.0e-06 7.8e-05 3.6e-06
12 PL alternative polyA XM_006247304.5 0.08 0.05 2.0e-09 0.07 0.08 0.08 0.08 1.6e-08 7.7e-09 2.5e-09 5.2e-09
13 PL alternative polyA NM_001107048.1 0.12 0.08 4.3e-10 0.07 0.09 0.1 0.1 2.3e-08 4.6e-10 1.4e-10 8.9e-11
14 BLA alternative polyA NM_001107048.1 0.07 0.05 1.1e-03 0.03 0.03 0.02 0.02 9.4e-03 1.5e-02 2.3e-02 2.9e-02
15 BLA alternative polyA XM_006247304.5 0.07 0.05 2.9e-03 0.03 0.03 0.02 0.03 7.7e-03 1.1e-02 2.4e-02 8.5e-03
16 Brain mRNA stability Msl1 0.04 0.03 2.9e-03 0.03 0.02 0.02 0.02 6.1e-04 3.9e-03 2.4e-03 3.0e-03
17 NAcc alternative polyA NM_001107048.1 0.07 0.04 1.2e-15 0.12 0.11 0.11 0.11 5.8e-17 4.0e-16 9.6e-16 9.2e-17
18 NAcc alternative polyA XM_006247304.5 0.09 0.05 2.6e-15 0.11 0.11 0.11 0.11 1.2e-16 6.2e-16 1.8e-16 1.4e-16
19 BLA gene expression Msl1 0.06 0.04 5.5e-03 0.04 0.02 0.02 0.03 3.1e-03 3.1e-02 2.9e-02 7.6e-03
20 IC mRNA stability Msl1 0.07 0.05 5.4e-03 0.05 0.01 0.01 0.03 3.5e-03 9.2e-02 1.0e-01 2.3e-02
21 Liver gene expression Msl1 0.3 0.12 0.0e+00 0.21 0.21 0.22 0.22 4.1e-23 2.5e-23 2.2e-24 1.6e-24
22 pVTA mRNA stability Msl1 0.06 0.05 1.1e-03 0.04 0.02 0.02 0.03 6.6e-04 4.8e-03 8.8e-03 1.2e-03
23 Adipose gene expression Msl1 0.08 0.04 3.9e-10 0.1 0.08 0.09 0.1 3.3e-11 2.8e-09 2.8e-10 1.0e-10
24 pVTA alternative polyA NM_001107048.1 0.07 0.05 5.4e-06 0.05 0.06 0.07 0.06 4.7e-05 1.1e-05 4.3e-06 7.2e-06
25 pVTA alternative polyA XM_006247304.5 0.07 0.05 7.2e-06 0.05 0.06 0.07 0.07 4.0e-05 9.5e-06 4.4e-06 4.1e-06
26 Brain gene expression Msl1 0.05 0.03 1.9e-05 0.04 0.05 0.04 0.04 7.2e-05 3.9e-05 8.5e-05 7.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density2.24.05.51.9-1.71.9-1.91.82.1-2.12.1-2.1-1.91.5-2.2-2.32.1-2.1-2.12.2-2.2-2.1-2.1-2.3-1.62.01.41.62.2
Area under the delay curve0.30.50.70.7-0.70.7-0.70.50.6-0.60.6-0.6-0.50.7-0.7-0.80.9-0.9-0.90.6-0.6-0.8-0.8-0.7-0.50.60.70.70.5
BMI with tail2.69.012.8-3.33.5-3.33.3-3.2-3.13.1-3.13.13.1-3.62.72.7-2.82.82.8-2.92.92.52.52.53.5-2.7-3.5-3.2-2.1
BMI without tail0.73.87.5-2.12.5-2.22.2-2.1-2.12.1-2.12.12.0-2.51.61.5-1.61.61.6-1.81.91.01.01.32.2-1.9-2.7-2.4-1.3
Body weight6.729.538.0-5.96.1-5.85.8-6.0-5.65.6-5.65.65.8-6.25.15.0-5.35.35.3-5.35.34.74.74.75.9-5.0-5.6-5.4-4.2
Weight adjusted by age0.10.41.3-0.70.7-0.50.4-0.9-0.60.6-0.60.60.7-0.80.60.6-0.70.70.7-0.50.50.80.80.21.1-0.00.20.10.2
Bone surface0.10.20.50.10.4-0.10.10.10.2-0.20.2-0.2-0.2-0.5-0.5-0.50.5-0.5-0.50.3-0.3-0.6-0.6-0.70.40.2-0.3-0.30.7
Bone volume0.20.31.30.20.20.1-0.10.40.6-0.60.6-0.6-0.5-0.4-0.7-0.60.7-0.7-0.70.7-0.7-0.7-0.7-0.90.40.5-0.3-0.31.1
Breakpoint value in progressive ratio session0.10.20.3-0.30.2-0.10.1-0.5-0.50.5-0.50.50.5-0.10.40.3-0.50.50.50.0-0.00.50.50.20.50.10.40.4-0.1
Number of licking bursts0.00.10.80.10.10.1-0.10.40.1-0.10.1-0.1-0.5-0.2-0.20.00.4-0.4-0.40.4-0.4-0.1-0.1-0.20.50.6-0.3-0.40.9
Context. condit. distance diff. score1.21.43.7-1.00.7-0.90.9-1.3-1.41.4-1.41.41.4-0.51.11.0-1.31.31.3-1.41.31.41.41.40.5-1.60.1-0.0-1.9
Locomotion velocity, session 10.50.51.2-0.71.1-0.90.9-0.8-0.50.5-0.50.50.8-1.10.70.6-0.40.40.4-0.70.70.80.80.60.9-0.8-0.7-1.0-0.4
Locomotion distance, session 12.12.75.0-1.82.2-2.02.0-1.7-1.41.4-1.41.41.6-2.21.71.6-1.31.31.3-1.51.41.01.01.22.0-1.6-2.2-2.1-1.0
Locomotion velocity, session 20.10.10.3-0.20.4-0.30.3-0.6-0.30.3-0.30.30.5-0.40.20.1-0.30.30.3-0.50.40.20.20.2-0.0-0.4-0.2-0.2-0.4
Locomotion distance, session 20.20.31.6-0.50.8-0.60.6-0.4-0.20.2-0.20.20.3-0.90.30.3-0.00.00.0-0.10.0-0.3-0.3-0.20.9-0.1-1.3-1.00.3
Locomotion velocity, session 30.10.10.40.2-0.30.3-0.3-0.10.1-0.10.1-0.10.10.4-0.3-0.5-0.10.10.1-0.1-0.1-0.5-0.5-0.4-0.40.10.40.6-0.0
Locomotion distance, session 30.20.30.5-0.60.5-0.50.5-0.6-0.50.5-0.50.50.6-0.50.60.5-0.50.50.5-0.50.40.40.40.40.7-0.4-0.6-0.4-0.3
Stereotopy head waving bouts, day 32.83.34.52.0-2.01.9-1.91.71.7-1.71.7-1.7-1.71.9-2.0-2.11.8-1.8-1.81.5-1.4-2.1-2.1-2.0-1.91.51.92.11.3
Stereotopy head waving duration, day 30.30.30.90.6-0.50.5-0.50.40.4-0.40.4-0.4-0.40.5-0.8-0.80.7-0.7-0.70.4-0.2-0.9-0.9-0.8-0.60.20.60.70.3
Locomotion velocity, session 71.21.32.1-1.21.4-1.31.3-1.1-1.01.0-1.01.01.1-1.41.21.3-0.90.90.9-1.21.31.01.00.91.5-0.9-1.2-1.3-0.5
Locomotion distance, session 70.50.61.6-0.60.8-0.90.9-0.4-0.60.6-0.60.60.4-0.81.11.3-0.40.40.4-0.70.71.01.01.10.8-0.6-1.0-1.2-0.5
Stereotopy head waving bouts, day 70.60.71.40.9-0.70.9-0.90.60.7-0.70.7-0.7-0.70.7-1.1-1.11.0-1.0-1.00.6-0.7-1.1-1.1-1.2-0.60.80.81.01.0
Stereotopy head waving duration, day 70.30.40.90.5-0.50.6-0.60.10.4-0.40.4-0.4-0.20.4-0.9-1.00.5-0.5-0.50.3-0.4-0.8-0.8-0.9-0.40.50.71.00.6
Locomotion velocity, session 87.28.710.4-3.02.9-3.13.1-3.1-3.03.0-3.03.03.2-2.83.02.9-3.03.03.0-3.02.93.13.13.12.5-3.2-2.2-2.4-3.2
Locomotion distance, session 81.31.82.4-1.41.5-1.51.5-1.5-1.41.4-1.41.41.5-1.51.31.3-1.31.31.3-1.31.21.21.21.21.4-1.5-1.2-1.2-1.3
Degree of sensitization distance0.91.01.8-0.81.0-1.11.1-0.6-0.90.9-0.90.90.7-0.91.21.3-0.70.70.7-1.01.11.31.31.40.6-1.1-1.0-1.2-1.0
Degree of sensitization stereotypy0.60.71.20.8-0.70.8-0.80.60.7-0.70.7-0.7-0.70.6-1.0-1.01.0-1.0-1.00.6-0.8-0.9-0.9-1.1-0.40.80.80.91.0
Conditioned locomotion0.30.30.80.6-0.70.6-0.60.30.5-0.50.5-0.5-0.30.7-0.6-0.70.5-0.5-0.50.4-0.4-0.4-0.4-0.5-0.90.40.80.80.3
Cocaine response after cond. corrected0.40.61.90.9-0.20.5-0.50.70.6-0.60.6-0.6-0.80.0-0.9-0.81.4-1.4-1.40.9-0.9-0.8-0.8-1.00.20.80.10.11.2
Cocaine response after cond. not corrected0.50.72.10.9-0.20.5-0.50.80.6-0.60.6-0.6-0.90.0-0.9-0.71.5-1.5-1.51.0-1.0-0.6-0.6-1.00.40.90.40.21.3
Cocaine response before conditioning0.00.10.40.2-0.20.2-0.20.20.1-0.10.1-0.1-0.20.2-0.1-0.00.3-0.3-0.30.3-0.30.10.1-0.00.00.00.70.50.0
Saline control response0.60.81.8-0.71.2-1.01.0-0.9-0.90.9-0.90.90.9-1.20.70.9-0.30.30.3-0.90.91.01.00.71.3-0.9-0.6-0.8-0.6
Bone: connectivity density3.55.67.52.3-2.12.3-2.32.22.3-2.32.3-2.3-2.22.0-2.6-2.72.5-2.5-2.52.4-2.5-2.7-2.7-2.7-2.12.31.82.02.4
Bone: cortical apparent density5.07.911.63.1-3.33.1-3.13.12.7-2.72.7-2.7-2.93.4-2.5-2.62.7-2.7-2.72.8-2.8-2.3-2.3-2.2-3.22.43.23.01.9
Bone: cortical area0.10.10.40.3-0.30.3-0.30.30.3-0.30.3-0.3-0.30.2-0.4-0.20.3-0.3-0.30.2-0.3-0.2-0.2-0.40.00.20.60.40.4
Bone: cortical porosity0.30.30.80.4-0.10.4-0.40.40.4-0.40.4-0.4-0.50.0-0.7-0.50.7-0.7-0.70.6-0.6-0.4-0.4-0.70.10.60.40.20.9
Bone: cortical porosity0.10.10.40.10.3-0.00.00.10.3-0.30.3-0.3-0.1-0.4-0.4-0.20.5-0.5-0.50.2-0.2-0.1-0.1-0.50.40.20.1-0.20.6
Bone: cortical thickness1.01.74.11.3-1.51.5-1.51.11.1-1.11.1-1.1-1.11.5-1.3-1.31.2-1.2-1.21.2-1.3-0.9-0.9-1.2-1.11.12.01.90.9
Bone: cortical thickness5.16.29.82.4-2.62.7-2.72.12.5-2.52.5-2.5-2.12.6-2.7-2.82.2-2.2-2.22.4-2.3-2.3-2.3-2.7-2.42.33.13.12.0
Bone: cortical tissue density5.07.911.53.1-3.33.1-3.13.12.7-2.72.7-2.7-3.03.4-2.5-2.72.7-2.7-2.72.8-2.8-2.3-2.3-2.2-3.22.53.13.01.9
Condit. Reinf. active minus inactive responses1.21.42.21.3-1.41.4-1.41.21.0-1.01.0-1.0-1.11.5-1.1-1.31.1-1.1-1.11.1-1.0-1.2-1.2-1.1-1.31.21.31.30.8
Condit. Reinf. active-inactive response ratio1.51.63.21.5-1.71.5-1.51.31.0-1.01.0-1.0-1.21.8-1.1-1.31.1-1.1-1.11.1-1.0-1.1-1.1-1.0-1.61.21.61.70.7
Condit. Reinf. active responses1.11.42.01.3-1.41.3-1.31.21.2-1.21.2-1.2-1.11.4-1.1-1.21.0-1.0-1.01.1-1.0-1.1-1.1-1.1-1.21.21.41.30.8
Condit. Reinf. inactive responses0.10.10.30.1-0.10.2-0.20.30.6-0.60.6-0.6-0.30.0-0.2-0.20.2-0.2-0.20.3-0.4-0.3-0.3-0.40.10.40.20.00.4
Incentive salience index mean2.12.73.31.8-1.81.8-1.81.81.6-1.61.6-1.6-1.81.8-1.6-1.61.7-1.7-1.71.6-1.5-1.6-1.6-1.5-1.71.71.61.41.4
Condit. Reinf. lever presses1.31.92.71.5-1.21.3-1.31.61.5-1.51.5-1.5-1.61.2-1.3-1.21.5-1.5-1.51.3-1.3-1.3-1.3-1.3-1.11.41.20.91.5
Condit. Reinf. active minus inactive responses0.71.12.10.8-1.01.1-1.11.11.3-1.31.3-1.3-1.21.0-0.9-0.80.8-0.8-0.81.2-1.3-0.9-0.9-1.0-0.61.40.90.81.4
Condit. Reinf. active-inactive response ratio0.60.91.80.7-0.80.9-0.91.11.2-1.21.2-1.2-1.10.7-0.9-0.70.8-0.8-0.81.0-1.2-1.0-1.0-1.0-0.41.30.40.51.3
Condit. Reinf. active responses1.31.93.31.1-1.21.3-1.31.41.6-1.61.6-1.6-1.51.1-1.2-1.11.2-1.2-1.21.5-1.6-1.4-1.4-1.4-0.71.81.00.91.8
Condit. Reinf. inactive responses1.21.82.51.3-1.11.3-1.31.41.5-1.51.5-1.5-1.41.0-1.3-1.21.5-1.5-1.51.4-1.4-1.4-1.4-1.5-0.81.51.00.81.6
Condit. Reinf. lever presses0.10.10.30.2-0.40.4-0.40.20.2-0.20.2-0.2-0.20.5-0.3-0.20.3-0.3-0.30.3-0.4-0.5-0.5-0.4-0.10.40.50.50.3
Condit. Reinf. lever reinforcers received1.52.23.51.3-1.41.5-1.51.51.7-1.71.7-1.7-1.51.3-1.3-1.21.3-1.3-1.31.6-1.6-1.5-1.5-1.5-0.91.91.21.11.8
Conditioned reinforcement - actives0.00.10.40.1-0.30.2-0.20.40.0-0.00.0-0.0-0.40.40.30.4-0.10.10.10.1-0.10.70.70.6-0.00.30.2-0.10.2
Conditioned reinforcement - inactives0.10.30.60.7-0.70.5-0.50.80.5-0.50.5-0.5-0.70.7-0.4-0.40.4-0.4-0.40.8-0.8-0.5-0.5-0.2-0.70.30.10.10.1
Conditioned locomotion0.30.51.40.8-0.80.7-0.71.20.7-0.70.7-0.7-1.20.7-0.2-0.10.7-0.7-0.70.7-0.7-0.3-0.3-0.2-0.70.90.20.01.1
Patch foraging indifference point 0 sec1.23.34.81.9-2.01.9-1.92.01.7-1.71.7-1.7-2.02.1-1.6-1.61.9-1.9-1.91.9-1.9-2.0-2.0-1.6-2.21.61.41.61.4
Patch foraging indifference point AUC0.00.00.10.00.3-0.10.1-0.30.0-0.00.0-0.00.3-0.3-0.2-0.20.1-0.1-0.1-0.10.2-0.2-0.2-0.30.2-0.10.30.3-0.0
Delay disc. indifference point, 0s delay1.92.23.11.7-1.41.4-1.41.51.4-1.41.4-1.4-1.51.4-1.4-1.31.8-1.8-1.81.5-1.5-1.6-1.6-1.5-1.01.51.21.31.4
Delay disc. indifference point, 16s delay0.40.62.40.8-0.90.8-0.80.30.5-0.50.5-0.5-0.20.9-1.0-1.10.6-0.6-0.60.3-0.3-0.2-0.2-0.5-1.20.31.51.5-0.2
Delay disc. indifference point, 2s delay1.01.12.11.1-0.80.9-0.91.21.1-1.11.1-1.1-1.20.7-0.7-0.71.4-1.4-1.41.0-1.1-1.1-1.1-1.00.01.20.40.31.4
Delay disc. indifference point, 24s delay0.10.10.3-0.20.1-0.20.2-0.3-0.60.6-0.60.60.3-0.10.20.1-0.30.30.3-0.40.50.40.40.6-0.5-0.3-0.0-0.0-0.5
Delay disc. indifference point, 4s delay1.01.11.70.9-1.01.1-1.10.81.1-1.11.1-1.1-0.80.9-1.1-1.11.1-1.1-1.11.1-1.1-0.7-0.7-1.0-0.51.21.31.21.1
Delay disc. indifference point, 8s delay0.10.10.30.3-0.30.3-0.30.30.2-0.20.2-0.2-0.30.3-0.4-0.50.4-0.4-0.40.2-0.2-0.5-0.5-0.3-0.40.40.10.20.4
Indifference point function ln k0.00.10.50.0-0.40.2-0.2-0.0-0.30.3-0.30.30.10.4-0.0-0.2-0.00.00.0-0.30.3-0.0-0.00.2-0.7-0.20.20.3-0.4
Indifference point function log k0.00.10.50.0-0.40.2-0.2-0.0-0.30.3-0.30.30.10.4-0.0-0.2-0.00.00.0-0.30.3-0.0-0.00.2-0.7-0.20.20.3-0.4
Patch foraging total patch changes 0 sec0.82.23.41.6-1.61.5-1.51.71.4-1.41.4-1.4-1.61.7-1.2-1.31.7-1.7-1.71.5-1.5-1.7-1.7-1.3-1.91.21.11.21.1
Patch foraging total patch changes 12 sec4.66.27.82.4-2.32.4-2.42.52.6-2.62.6-2.6-2.62.1-2.4-2.42.4-2.4-2.42.7-2.7-2.7-2.7-2.7-2.02.62.02.12.8
Patch foraging total patch changes 18 sec0.20.50.90.6-0.60.6-0.60.60.8-0.80.8-0.8-0.60.6-0.6-0.60.6-0.6-0.60.7-0.7-0.9-0.9-0.8-0.50.70.70.70.7
Patch foraging total patch changes 24 sec0.41.21.91.1-1.11.2-1.20.91.1-1.11.1-1.1-1.01.0-1.0-1.21.2-1.2-1.21.4-1.4-0.8-0.8-1.1-0.81.21.31.31.2
Patch foraging total patch changes 6 sec1.83.14.71.7-1.61.6-1.61.71.9-1.91.9-1.9-1.71.6-1.7-1.71.8-1.8-1.81.7-1.7-2.2-2.2-1.9-1.71.41.41.41.4
Patch foraging time to switch 0 sec0.00.10.20.4-0.20.3-0.30.30.4-0.40.4-0.4-0.30.2-0.2-0.20.3-0.3-0.30.4-0.4-0.5-0.5-0.4-0.00.3-0.10.00.5
Patch foraging water rate 0 sec0.00.20.50.2-0.50.4-0.40.40.3-0.30.3-0.3-0.40.5-0.4-0.40.4-0.4-0.40.4-0.5-0.4-0.4-0.3-0.70.50.40.40.2
Patch foraging water rate 12 sec0.10.31.1-0.50.0-0.10.1-0.5-0.60.6-0.60.60.50.00.40.4-0.70.70.7-0.30.21.01.00.70.1-0.00.30.2-0.3
Patch foraging water rate 18 sec0.30.61.40.6-0.60.8-0.80.60.5-0.50.5-0.5-0.70.5-1.0-1.10.7-0.7-0.70.9-0.9-0.6-0.6-0.9-0.60.90.80.91.2
Patch foraging water rate 24 sec0.60.81.20.7-0.90.9-0.91.01.1-1.11.1-1.1-1.00.9-1.0-1.00.7-0.7-0.70.8-0.8-1.0-1.0-0.9-1.10.80.70.70.8
Patch foraging water rate 6 sec1.62.33.41.4-1.61.7-1.71.41.4-1.41.4-1.4-1.41.6-1.7-1.71.6-1.6-1.61.4-1.5-1.1-1.1-1.4-1.41.81.71.71.6
Seeking ratio, delayed vs. immediate footshock0.20.31.60.3-0.60.4-0.40.10.2-0.20.2-0.20.00.70.30.40.4-0.4-0.40.1-0.11.31.30.7-0.1-0.11.20.9-0.8
Distance traveled before self-admin0.00.10.50.00.00.2-0.2-0.10.4-0.40.4-0.40.0-0.1-0.4-0.10.1-0.1-0.10.3-0.30.30.3-0.30.10.40.70.40.4
Distance traveled after self-admin0.20.40.7-0.80.8-0.70.7-0.9-0.50.5-0.50.50.9-0.80.30.3-0.70.70.7-0.60.60.30.30.40.5-0.7-0.5-0.5-0.7
Extensor digitorum longus weight9.538.143.8-6.26.0-6.36.3-6.1-6.36.3-6.36.36.2-5.76.56.4-6.26.26.2-6.46.46.56.56.65.5-6.1-5.0-5.5-6.1
Bone: elastic displacement0.00.10.30.1-0.0-0.10.10.4-0.10.1-0.10.1-0.30.00.40.40.2-0.2-0.2-0.0-0.1-0.1-0.10.20.0-0.2-0.6-0.4-0.1
Bone: elastic work0.10.10.30.3-0.10.2-0.20.30.2-0.20.2-0.2-0.30.0-0.3-0.30.5-0.5-0.50.3-0.4-0.4-0.4-0.50.20.20.10.20.5
Bone: endosteal estimation2.04.98.3-2.32.8-2.62.6-2.1-2.12.1-2.12.12.0-2.92.02.1-1.91.91.9-2.12.21.81.81.82.3-2.0-2.9-2.9-1.3
Bone: endosteal perimeter1.22.94.7-1.92.0-1.91.9-1.5-1.61.6-1.61.61.5-2.01.71.9-1.71.71.7-1.71.71.41.41.61.8-1.6-2.1-2.2-1.2
Epididymis fat weight0.10.61.4-1.01.0-0.80.8-0.9-0.80.8-0.80.80.8-1.10.70.9-0.60.60.6-0.70.60.90.90.61.2-0.5-0.6-0.8-0.2
Delta time in closed arm before/after self-admin3.93.75.3-2.22.2-2.22.2-2.3-1.91.9-1.91.92.3-2.21.81.5-1.91.91.9-2.02.01.01.01.22.3-2.2-1.6-1.4-2.0
Delta time in open arm before/after self-admin0.10.10.7-0.0-0.00.0-0.0-0.1-0.30.3-0.30.30.10.1-0.1-0.1-0.10.10.10.0-0.00.80.80.5-0.0-0.20.30.1-0.4
Diff in mean of infusions in LGA sessions0.00.10.2-0.3-0.00.1-0.1-0.2-0.20.2-0.20.20.10.00.1-0.0-0.40.40.40.2-0.2-0.1-0.1-0.20.30.30.10.20.3
Delay discount exponential model param0.20.30.5-0.50.5-0.50.5-0.3-0.40.4-0.40.40.3-0.50.60.7-0.60.60.6-0.40.40.60.60.50.4-0.5-0.6-0.6-0.3
Extinction: sum of active levers before priming1.21.82.9-1.31.5-1.51.5-1.5-1.71.7-1.71.71.4-1.61.00.8-1.31.31.3-1.41.41.01.01.01.5-1.4-1.1-1.1-1.1
Active lever presses in extinction session 60.50.51.90.50.30.3-0.3-0.00.3-0.30.3-0.3-0.2-0.5-1.0-0.91.0-1.0-1.00.5-0.5-0.9-0.9-1.40.30.70.10.21.4
Bone: final force0.40.71.90.8-0.20.6-0.60.70.8-0.80.8-0.8-0.80.1-1.1-0.91.2-1.2-1.20.6-0.7-0.8-0.8-1.1-0.10.80.40.31.4
Bone: final moment0.30.41.40.6-0.10.4-0.40.50.6-0.60.6-0.6-0.6-0.1-0.9-0.71.0-1.0-1.00.5-0.5-0.7-0.7-1.00.10.60.30.11.2
Food consumed during 24 hour testing period0.51.01.4-1.11.0-1.11.1-0.9-0.90.9-0.90.90.9-1.01.01.2-1.11.11.1-0.90.91.01.01.01.0-1.1-1.0-1.0-0.8
Glucose0.10.21.10.10.5-0.30.3-0.00.1-0.10.1-0.1-0.0-0.6-0.10.30.9-0.9-0.9-0.10.10.10.1-0.21.0-0.20.1-0.30.3
Heart weight3.15.06.4-2.12.4-2.42.4-2.1-2.22.2-2.22.22.1-2.32.42.4-2.02.02.0-2.12.22.42.42.32.4-2.5-2.1-2.2-2.2
Delay discount hyperbolic model param0.20.20.4-0.50.5-0.50.5-0.3-0.40.4-0.40.40.3-0.50.50.6-0.60.60.6-0.40.40.60.60.50.2-0.5-0.5-0.5-0.3
Intermittent access intake day 1-15 change0.00.20.6-0.0-0.40.4-0.4-0.10.1-0.10.1-0.10.10.4-0.5-0.60.1-0.1-0.10.5-0.5-0.5-0.5-0.60.10.50.60.80.2
Intermittent access intake escalation0.00.10.5-0.1-0.30.3-0.4-0.10.0-0.00.0-0.00.10.4-0.5-0.6-0.00.00.00.5-0.5-0.5-0.5-0.60.10.40.60.70.1
Intermittent access intake escalation 20.10.20.5-0.70.4-0.40.4-0.5-0.60.6-0.60.60.5-0.40.20.1-0.60.60.6-0.10.10.10.10.20.6-0.3-0.5-0.3-0.3
Intermitt. access day 1 inactive lever presses0.23.05.31.5-1.61.7-1.71.11.7-1.71.7-1.7-1.11.6-2.1-2.31.6-1.6-1.61.8-1.8-2.0-2.0-2.1-1.21.51.92.21.2
Intermitt. access day 15 inactive lever presses0.52.64.11.6-1.91.7-1.71.61.5-1.51.5-1.5-1.52.0-1.7-1.81.4-1.4-1.41.7-1.7-2.0-2.0-1.5-1.71.61.21.41.0
Intermitt. access escalation Index0.82.54.2-2.01.6-1.51.5-2.1-1.61.6-1.61.62.0-1.61.10.9-2.12.12.1-1.61.61.41.41.01.6-1.5-0.8-0.6-1.2
Intermittent access day 1 total infusions0.00.00.10.1-0.10.1-0.10.20.4-0.40.4-0.4-0.10.20.10.1-0.20.20.20.3-0.30.30.30.2-0.3-0.10.20.0-0.1
Intermittent access day 15 total infusions0.00.10.6-0.1-0.30.2-0.2-0.20.1-0.10.1-0.10.20.3-0.3-0.3-0.20.20.20.3-0.3-0.1-0.1-0.2-0.0-0.00.80.7-0.3
Intermittent access terminal intake (last 3 days)0.10.20.50.3-0.60.5-0.50.20.4-0.40.4-0.4-0.20.6-0.6-0.70.0-0.0-0.00.7-0.7-0.4-0.4-0.4-0.50.30.70.70.0
Intermittent access total infusions0.10.10.40.0-0.30.2-0.2-0.10.2-0.20.2-0.20.10.3-0.2-0.2-0.30.30.30.4-0.40.20.20.0-0.2-0.10.60.5-0.3
Intermittent access day 1 locomotion0.00.10.20.4-0.20.1-0.10.50.4-0.40.4-0.4-0.40.20.20.20.2-0.2-0.20.1-0.10.10.10.2-0.4-0.00.0-0.20.0
Intermittent access day 15 total locomotion0.10.30.80.7-0.40.4-0.40.90.6-0.60.6-0.6-0.90.4-0.00.10.8-0.8-0.80.6-0.6-0.5-0.5-0.3-0.30.4-0.1-0.30.7
Intermittent access total locomotion0.70.91.41.1-1.00.9-0.91.21.0-1.01.0-1.0-1.11.0-0.7-0.61.0-1.0-1.01.0-1.0-0.8-0.8-0.7-0.90.90.70.60.8
Intermittent access standard deviation0.42.33.31.3-1.71.6-1.61.31.5-1.51.5-1.5-1.31.7-1.7-1.71.1-1.1-1.11.8-1.8-1.6-1.6-1.5-1.41.61.51.71.0
Left kidney weight0.21.74.0-1.51.3-1.21.2-2.0-1.31.3-1.31.31.9-1.30.70.6-1.81.81.8-1.51.50.60.60.60.9-1.3-0.6-0.5-1.3
Right kidney weight0.00.10.4-0.30.5-0.20.2-0.6-0.00.0-0.00.00.5-0.6-0.5-0.5-0.30.30.3-0.10.0-0.5-0.5-0.60.40.1-0.3-0.10.4
Cocaine induced anxiety1.43.85.6-2.22.1-1.91.9-2.4-2.12.1-2.12.12.3-2.11.51.4-2.32.32.3-1.91.91.21.21.42.0-1.7-1.9-1.6-1.6
Post-drug Anxiety0.80.91.6-1.10.8-0.80.8-1.3-1.11.1-1.11.11.2-0.80.70.6-1.31.31.3-0.90.90.50.50.60.9-0.7-0.8-0.5-1.0
Baseline Anxiety1.01.72.81.4-1.51.4-1.41.71.4-1.41.4-1.4-1.61.5-0.8-0.61.6-1.6-1.61.3-1.3-0.7-0.7-0.8-1.11.41.41.11.1
Tail length0.31.62.6-1.21.2-1.21.2-1.5-1.61.6-1.61.61.5-1.11.31.2-1.21.21.2-1.31.31.21.21.30.9-1.2-0.8-0.8-1.3
Length with tail2.310.214.1-3.53.4-3.23.2-3.8-3.43.4-3.43.43.7-3.33.13.0-3.43.43.4-3.13.02.92.92.83.2-2.8-2.6-2.6-2.7
Length without tail1.99.811.5-3.43.4-3.33.3-3.3-3.13.1-3.13.13.3-3.43.23.3-3.03.03.0-3.13.03.23.23.03.4-2.8-2.8-2.9-2.4
Times rat made contact with spout0.70.91.60.9-0.70.7-0.71.31.2-1.21.2-1.2-1.30.7-0.8-0.71.1-1.1-1.11.0-1.0-0.9-0.9-0.8-0.60.80.00.11.0
Lifetime Intake0.10.20.80.3-0.50.5-0.50.10.4-0.40.4-0.4-0.10.6-0.4-0.5-0.00.00.00.6-0.6-0.0-0.0-0.2-0.40.20.90.8-0.1
Liver weight, left0.30.51.1-0.61.0-0.80.8-0.7-0.80.8-0.80.80.6-1.00.70.7-0.40.40.4-0.70.60.60.60.61.1-0.6-0.9-1.0-0.2
Liver weight, right0.61.02.61.2-0.60.8-0.80.40.9-0.90.9-0.9-0.40.6-1.4-1.61.1-1.1-1.10.6-0.6-1.4-1.4-1.4-1.20.51.01.10.5
Locomotor activity0.30.52.00.5-0.40.6-0.60.70.5-0.50.5-0.5-0.80.2-0.8-0.60.8-0.8-0.81.0-1.0-0.3-0.3-0.6-0.11.10.30.21.4
Locomotor testing distance1.22.94.21.5-1.71.8-1.81.71.6-1.61.6-1.6-1.81.6-1.9-1.71.7-1.7-1.71.9-1.9-1.6-1.6-1.7-1.52.01.51.52.0
Locomotor testing rearing2.810.112.93.3-3.43.3-3.33.03.2-3.23.2-3.2-3.03.3-3.4-3.43.2-3.2-3.22.9-2.9-3.2-3.2-3.2-3.63.13.03.22.7
Locomotion in novel chamber4.46.09.12.9-2.32.5-2.52.62.7-2.72.7-2.7-2.52.2-2.2-2.03.0-3.0-3.02.4-2.4-1.5-1.5-2.2-1.82.42.52.22.3
Locomotion in novel chamber post-restriction0.20.51.20.4-0.30.5-0.50.80.8-0.80.8-0.8-0.90.2-0.6-0.40.7-0.7-0.70.8-0.8-0.8-0.8-0.90.00.9-0.3-0.11.1
Fecal boli incidents, locomotor time 10.10.31.1-0.30.6-0.70.7-0.1-0.10.1-0.10.10.2-0.60.91.0-0.10.10.1-0.60.60.50.50.60.3-0.6-1.0-1.1-0.5
Change in fecal boli incidents, locomotor task0.10.10.30.3-0.20.2-0.20.1-0.20.2-0.20.2-0.20.1-0.1-0.10.5-0.5-0.50.3-0.30.10.10.10.30.20.10.10.3
Time >=10cm from walls, locomotor time 10.20.20.70.7-0.70.5-0.50.50.2-0.20.2-0.2-0.40.7-0.0-0.10.6-0.6-0.60.2-0.2-0.3-0.3-0.2-0.30.30.80.70.0
Bouts of movement, locomotor time 10.40.51.2-1.00.8-0.70.7-1.1-0.80.8-0.80.81.0-0.80.30.1-1.01.01.0-0.70.6-0.1-0.10.10.5-0.4-0.6-0.4-0.4
Total resting periods, locomotor time 10.91.11.9-1.41.2-1.11.1-1.3-1.11.1-1.11.11.3-1.30.80.7-1.31.31.3-1.10.90.30.30.50.9-0.7-1.1-1.0-0.6
Rest time, locomotor task time 10.10.10.8-0.10.2-0.10.10.20.2-0.20.2-0.2-0.2-0.2-0.2-0.3-0.10.10.10.0-0.1-0.9-0.9-0.5-0.30.1-0.7-0.50.4
Distance moved, locomotor task time 10.00.10.60.2-0.00.1-0.1-0.10.3-0.30.3-0.30.10.10.10.10.3-0.3-0.30.0-0.00.50.50.00.6-0.10.80.5-0.3
Vertical activity count, locomotor time 10.10.62.6-0.50.6-0.60.6-0.5-0.60.6-0.60.60.5-0.61.11.2-0.20.20.2-0.30.31.61.61.11.5-0.5-0.0-0.4-0.6
Time >=10cm from walls, locomotor time 20.30.71.51.2-0.90.9-0.91.00.8-0.80.8-0.8-1.00.8-0.40.01.1-1.1-1.10.8-0.80.30.3-0.3-0.21.11.20.81.2
Bouts of movement, locomotor time 20.20.52.00.6-0.80.9-0.90.20.5-0.50.5-0.5-0.30.9-1.0-1.10.4-0.4-0.40.3-0.3-0.7-0.7-0.8-1.40.71.11.10.6
Total resting periods, locomotor time 20.10.31.50.4-0.70.7-0.70.00.3-0.30.3-0.3-0.00.7-0.8-1.00.1-0.1-0.10.1-0.1-0.5-0.5-0.6-1.20.51.01.00.3
Rest time, locomotor task time 20.50.81.0-0.91.0-0.90.9-1.0-1.01.0-1.01.00.9-1.00.90.8-0.80.80.8-1.01.00.60.60.70.7-0.8-1.0-0.9-0.7
Distance moved, locomotor task time 20.10.21.1-0.20.6-0.50.5-0.4-0.10.1-0.10.10.4-0.70.40.30.1-0.1-0.1-0.40.50.30.30.11.1-0.6-0.1-0.3-0.4
Vertical activity count, locomotor time 20.30.62.3-0.60.7-0.70.7-0.6-0.70.7-0.70.70.6-0.71.10.9-0.40.40.4-0.60.61.11.10.91.5-0.8-0.5-0.7-0.8
Light reinforcement 11.14.96.72.0-2.22.3-2.32.02.1-2.12.1-2.1-2.12.1-2.4-2.42.1-2.1-2.12.5-2.5-2.6-2.6-2.5-2.02.31.92.12.2
Light reinforcement 20.30.81.70.8-0.30.6-0.60.80.7-0.70.7-0.7-0.80.2-1.0-1.01.3-1.3-1.31.0-1.0-1.3-1.3-1.2-0.30.60.20.31.1
Bone: marrow area1.94.67.8-2.22.7-2.52.5-2.1-2.12.1-2.12.12.0-2.81.92.1-1.81.81.8-2.12.11.71.71.82.2-2.0-2.8-2.8-1.3
Bone: maximum diameter0.00.00.2-0.00.10.1-0.10.00.2-0.20.2-0.2-0.1-0.1-0.2-0.1-0.10.10.10.2-0.1-0.2-0.2-0.30.10.30.1-0.00.5
Bone: maximum force0.10.10.6-0.30.7-0.40.4-0.4-0.30.3-0.30.30.4-0.8-0.00.10.0-0.0-0.0-0.40.30.20.2-0.10.7-0.3-0.3-0.40.2
Bone: maximum moment0.10.20.8-0.40.8-0.60.6-0.6-0.50.5-0.50.50.5-0.90.10.2-0.10.10.1-0.60.50.40.40.10.8-0.5-0.5-0.50.0
Mean time between licks in bursts0.42.33.8-1.51.6-1.71.7-1.2-1.41.4-1.41.41.2-1.61.61.7-1.61.61.6-1.41.41.41.41.61.4-1.5-1.9-2.0-1.2
Mean num. licks in bursts0.10.30.70.5-0.60.5-0.50.50.7-0.70.7-0.7-0.40.7-0.4-0.50.5-0.5-0.50.4-0.3-0.6-0.6-0.4-0.80.10.30.5-0.2
Cd content in liver1.61.72.7-1.21.2-1.31.3-1.0-1.31.3-1.31.31.0-1.21.41.4-1.41.41.4-1.21.31.31.31.51.1-1.3-1.6-1.5-1.3
Co content in liver1.72.03.4-1.31.0-1.31.3-1.2-1.41.4-1.41.41.3-0.91.61.5-1.61.61.6-1.41.41.51.51.70.7-1.6-1.2-1.1-1.8
Cu content in liver0.10.20.60.3-0.50.5-0.50.00.3-0.30.3-0.30.10.6-0.2-0.40.2-0.2-0.20.1-0.2-0.4-0.4-0.3-0.50.20.80.8-0.3
Fe content in liver1.62.03.4-1.51.8-1.71.7-1.5-1.11.1-1.11.11.5-1.81.31.5-1.31.31.3-1.31.41.11.11.01.8-1.5-1.5-1.6-1.1
K content in liver1.41.33.80.9-1.21.3-1.30.41.0-1.01.0-1.0-0.41.2-1.5-1.60.8-0.8-0.81.1-1.1-0.8-0.8-1.3-1.41.12.01.90.8
Mg content in liver1.21.34.91.1-1.51.4-1.40.40.8-0.80.8-0.8-0.41.6-1.3-1.60.8-0.8-0.80.8-0.8-0.7-0.7-1.0-1.80.82.12.20.2
Mn content in liver1.61.83.81.5-1.71.6-1.61.01.1-1.11.1-1.1-1.01.7-1.3-1.51.1-1.1-1.11.0-1.2-1.0-1.0-1.1-1.91.21.91.90.8
Na content in liver0.30.31.00.10.10.3-0.3-0.10.6-0.60.6-0.6-0.1-0.3-0.8-0.70.5-0.5-0.50.7-0.7-0.5-0.5-1.00.40.70.40.41.0
Rb content in liver1.92.23.41.8-1.51.4-1.41.61.5-1.51.5-1.5-1.51.5-1.4-1.41.8-1.8-1.81.2-1.3-1.6-1.6-1.4-1.51.11.21.31.0
Se content in liver8.09.412.83.2-3.33.4-3.42.72.9-2.92.9-2.9-2.73.3-3.4-3.52.8-2.8-2.82.9-3.0-2.8-2.8-3.1-3.33.13.63.62.6
Sr content in liver0.20.20.5-0.2-0.40.1-0.1-0.3-0.50.5-0.50.50.30.50.40.2-0.60.60.6-0.20.20.70.70.7-0.5-0.20.60.6-0.6
Zn content in liver3.94.55.72.1-2.22.3-2.31.82.1-2.12.1-2.1-1.82.2-2.3-2.41.9-1.9-1.92.0-1.9-2.4-2.4-2.3-2.32.02.22.31.6
Bone: minimum diameter0.51.01.8-0.91.3-1.11.1-1.1-1.01.0-1.01.01.0-1.30.81.0-0.70.70.7-1.11.10.90.90.81.3-1.0-0.9-1.0-0.6
Time in familiar zone, hab. session 10.20.20.70.20.4-0.10.10.30.4-0.40.4-0.4-0.4-0.6-0.4-0.20.6-0.6-0.60.1-0.1-0.2-0.2-0.50.60.3-0.1-0.40.9
Time in novel zone, hab. session 10.60.72.31.0-1.41.0-1.00.90.5-0.50.5-0.5-0.81.5-0.5-0.70.8-0.8-0.80.6-0.6-0.7-0.7-0.4-1.30.60.91.2-0.0
Total zone transitions, hab. session 11.72.43.1-1.61.5-1.61.6-1.5-1.51.5-1.51.51.5-1.41.81.6-1.61.61.6-1.61.51.71.71.71.5-1.6-1.2-1.4-1.7
Total locomotion distance, hab. session 10.00.00.1-0.1-0.20.0-0.00.0-0.10.1-0.10.10.00.20.20.2-0.20.20.20.0-0.00.10.10.20.1-0.20.10.2-0.3
Locomotion velocity, hab. session 10.30.41.1-0.80.4-0.50.5-0.6-0.70.7-0.70.70.6-0.30.70.6-1.01.01.0-0.20.20.80.80.70.6-0.6-0.2-0.2-0.7
Time in familiar zone, hab. session 20.40.50.90.6-0.40.6-0.60.50.5-0.50.5-0.5-0.50.3-0.9-0.90.8-0.8-0.81.0-0.9-0.6-0.6-0.9-0.20.70.70.70.8
Time in novel zone, hab. session 20.20.20.50.4-0.70.5-0.50.50.4-0.40.4-0.4-0.50.7-0.1-0.30.3-0.3-0.30.2-0.2-0.4-0.4-0.2-0.70.40.20.30.2
Total zone transitions, hab. session 21.11.42.4-1.01.3-1.41.4-0.9-1.21.2-1.21.20.9-1.31.41.4-0.60.60.6-1.11.01.01.01.21.4-1.3-1.4-1.6-1.0
Total locomotion distance, hab. session 20.40.51.6-0.70.8-0.80.8-0.3-0.60.6-0.60.60.3-0.80.91.0-0.40.40.4-0.30.20.20.20.51.2-0.6-1.3-1.2-0.3
Locomotion velocity, hab. session 20.60.82.0-1.01.0-1.01.0-0.6-0.90.9-0.90.90.6-1.01.21.2-0.70.70.7-0.50.40.60.60.81.4-0.8-1.3-1.3-0.6
Novel to familiar place preference ratio0.91.22.5-1.20.7-0.80.7-1.5-1.11.1-1.11.11.5-0.60.80.6-1.61.61.6-1.31.31.31.31.10.3-0.9-0.1-0.0-1.2
Novelty place preference0.81.12.3-1.00.5-0.60.6-1.3-1.01.0-1.01.01.3-0.40.80.6-1.51.51.5-1.31.21.41.41.10.1-0.80.10.1-1.2
Time in novel zone, NPP test0.50.61.3-0.70.2-0.30.3-1.0-0.80.8-0.80.81.0-0.10.40.3-1.11.11.1-0.90.81.11.10.8-0.1-0.40.40.4-0.8
Total zone transitions, NPP test0.71.03.6-0.91.4-1.31.3-0.4-0.60.6-0.60.60.4-1.51.21.3-0.40.40.4-0.60.50.80.80.91.6-0.9-1.7-1.9-0.3
Total locomotion distance, NPP test0.20.21.5-0.20.5-0.50.50.30.0-0.00.0-0.0-0.3-0.60.50.50.1-0.1-0.10.2-0.2-0.2-0.20.10.9-0.4-1.2-1.20.2
Locomotion velocity, NPP test0.40.62.5-0.71.0-1.01.0-0.2-0.20.2-0.20.20.2-1.00.91.0-0.50.50.5-0.40.30.10.10.51.1-0.9-1.6-1.6-0.4
Intraocular pressure2.54.16.7-2.12.1-2.32.3-1.7-1.51.5-1.51.51.8-2.02.42.5-2.12.12.1-2.22.31.51.52.11.6-2.1-2.6-2.6-2.2
Delta distance traveled before/after self-admin1.21.31.9-1.01.0-1.11.1-1.2-1.41.4-1.41.41.2-0.91.10.9-1.11.11.1-1.21.20.80.81.10.9-1.3-1.2-1.0-1.4
Delta ambulatory time before/after self-admin0.91.63.0-1.21.4-1.41.4-1.4-1.51.5-1.51.51.3-1.41.00.8-1.21.21.2-1.41.40.40.40.91.1-1.4-1.7-1.3-1.2
Parametrial fat weight0.40.82.30.7-0.60.8-0.80.90.9-0.90.9-0.9-1.00.4-1.0-0.90.9-0.9-0.91.2-1.1-1.1-1.1-1.1-0.51.30.10.21.5
Pavlov. Cond. lever latency2.22.74.5-1.61.1-1.31.3-1.8-1.91.9-1.91.91.9-0.91.71.5-1.81.81.8-1.61.62.02.02.00.8-1.7-0.5-0.5-2.1
Pavlov. Cond. magazine entry latency9.512.214.93.5-3.23.4-3.43.63.9-3.93.9-3.9-3.73.0-3.7-3.63.3-3.3-3.33.6-3.6-3.6-3.6-3.9-2.83.62.82.73.7
Pavlov. Cond. change in total contacts9.810.611.93.4-3.43.4-3.43.33.4-3.43.4-3.4-3.33.4-3.4-3.43.1-3.1-3.13.0-3.0-3.3-3.3-3.3-3.33.03.23.12.7
Pavlov. Cond. index score8.110.212.73.3-2.73.0-3.03.43.6-3.63.6-3.6-3.52.5-3.3-3.13.3-3.3-3.33.3-3.3-3.4-3.4-3.5-2.33.32.22.13.5
Pavlov. Cond. latency score6.07.710.12.8-2.32.6-2.63.03.1-3.13.1-3.1-3.02.1-2.9-2.72.9-2.9-2.92.8-2.8-3.1-3.1-3.1-1.92.91.71.73.2
Pavlov. Cond. lever contacts2.83.45.51.8-1.31.6-1.62.02.1-2.12.1-2.1-2.11.1-1.9-1.72.0-2.0-2.01.8-1.9-2.2-2.2-2.2-1.12.00.80.72.3
Pavlov. Cond. magazine entry number12.515.918.4-4.23.8-4.04.0-4.2-4.34.3-4.34.34.2-3.64.24.0-4.04.04.0-3.93.94.14.14.23.5-3.9-3.3-3.3-3.9
Pavlov. Cond. intertrial magazine entries1.21.52.3-1.01.0-1.11.1-1.2-1.51.5-1.51.51.3-0.91.41.2-0.90.90.9-1.31.51.31.31.40.7-1.2-0.9-0.9-1.5
Pavlov. Cond. lever-magazine prob. diff.9.712.115.03.6-3.13.3-3.33.73.9-3.93.9-3.9-3.82.9-3.6-3.43.6-3.6-3.63.6-3.5-3.7-3.7-3.8-2.63.52.42.43.7
Pavlov. Cond. response bias10.112.614.83.7-3.33.5-3.53.73.9-3.93.9-3.9-3.73.2-3.7-3.63.5-3.5-3.53.6-3.6-3.7-3.7-3.8-3.03.52.92.93.6
Pavlov. Cond. lever latency0.40.61.2-0.40.6-0.70.7-0.8-1.01.0-1.01.00.8-0.60.70.5-0.40.40.4-0.91.01.11.11.00.3-0.9-0.5-0.5-1.0
Pavlov. Cond. magazine entry latency0.10.10.7-0.50.4-0.30.3-0.2-0.20.2-0.20.20.2-0.40.50.6-0.50.50.50.2-0.10.20.20.20.8-0.1-0.1-0.3-0.1
Pavlov. Cond. change in total contacts0.41.01.41.0-1.11.0-1.01.21.2-1.21.2-1.2-1.11.1-0.7-0.60.8-0.8-0.80.9-0.9-1.1-1.1-0.9-0.81.01.00.80.8
Pavlov. Cond. index score0.10.20.60.1-0.20.2-0.20.50.6-0.60.6-0.6-0.50.2-0.1-0.00.2-0.2-0.20.6-0.6-0.8-0.8-0.50.20.50.0-0.10.6
Pavlov. Cond. latency score0.10.10.30.0-0.10.1-0.10.40.4-0.40.4-0.4-0.40.1-0.00.10.1-0.1-0.10.5-0.5-0.6-0.6-0.30.30.4-0.0-0.20.5
Pavlov. Cond. lever contacts0.40.61.30.5-0.60.6-0.60.81.0-1.01.0-1.0-0.90.5-0.7-0.50.6-0.6-0.61.0-1.0-1.2-1.2-1.0-0.10.90.30.31.0
Pavlov. Cond. magazine entry number0.10.10.5-0.10.1-0.20.2-0.3-0.40.4-0.40.40.3-0.10.10.1-0.10.10.1-0.50.50.70.70.5-0.3-0.3-0.4-0.2-0.3
Pavlov. Cond. intertrial magazine entries0.91.93.1-1.30.7-1.01.0-1.4-1.61.6-1.61.61.5-0.61.41.2-1.71.71.7-1.51.51.71.71.80.4-1.4-0.5-0.4-1.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.0-0.10.1-0.10.40.5-0.50.5-0.5-0.40.1-0.00.10.1-0.1-0.10.5-0.5-0.7-0.7-0.40.30.3-0.0-0.10.4
Pavlov. Cond. response bias0.91.32.10.8-0.91.0-1.01.11.4-1.41.4-1.4-1.10.8-1.0-0.80.9-0.9-0.91.4-1.4-1.4-1.4-1.3-0.31.30.80.71.3
Time in closed arm before self-admin1.72.97.31.8-1.91.7-1.71.71.7-1.71.7-1.7-1.71.9-2.0-2.01.5-1.5-1.51.4-1.4-1.9-1.9-1.5-2.71.31.31.41.1
Time in closed arm after self-admin0.10.20.6-0.2-0.20.0-0.0-0.40.1-0.10.1-0.10.50.3-0.2-0.5-0.50.50.5-0.40.4-0.3-0.3-0.1-0.7-0.40.70.8-0.8
Time in open arm before self-admin1.62.04.0-1.41.4-1.31.3-1.5-1.61.6-1.61.61.5-1.41.71.8-1.21.21.2-1.11.11.61.61.32.0-1.0-0.7-0.9-0.9
Time in open arm after self-admin0.40.51.6-0.50.5-0.50.5-0.5-0.90.9-0.90.90.5-0.50.60.8-0.40.40.4-0.30.31.31.31.00.8-0.4-0.3-0.5-0.5
Bone: periosteal estimation0.30.71.7-0.91.2-1.01.0-0.8-0.70.7-0.70.70.7-1.30.60.8-0.60.60.6-0.80.80.60.60.51.2-0.7-1.1-1.2-0.2
Bone: periosteal perimeter0.71.43.1-1.41.6-1.41.4-1.1-0.90.9-0.90.91.0-1.61.11.3-1.11.11.1-1.11.10.80.80.81.8-1.1-1.4-1.6-0.5
Bone: post-yield work1.01.72.4-1.41.4-1.41.4-1.3-1.21.2-1.21.21.3-1.41.21.2-1.51.51.5-1.51.51.11.11.21.1-1.4-1.2-1.3-1.2
Progressive ratio test 1 active lever presses0.00.00.20.2-0.20.2-0.20.00.2-0.20.2-0.2-0.00.2-0.3-0.2-0.00.00.00.1-0.10.00.0-0.1-0.30.10.40.30.1
Progressive ratio test 1 breakpoint0.00.00.10.1-0.10.1-0.1-0.10.1-0.10.1-0.10.10.1-0.2-0.2-0.10.10.10.0-0.00.00.0-0.0-0.2-0.00.30.2-0.0
Progressive ratio test 1 inactive lever presses0.10.40.90.5-0.70.6-0.60.20.5-0.50.5-0.5-0.20.7-0.8-1.00.2-0.2-0.20.6-0.6-0.8-0.8-0.7-0.60.50.90.90.2
Progressive ratio test 2 active lever presses0.60.91.31.0-1.11.0-1.01.11.1-1.11.1-1.1-1.01.1-0.7-0.60.8-0.8-0.81.2-1.2-0.1-0.1-0.4-1.01.11.10.80.9
Progressive ratio test 2 breakpoint0.71.01.41.1-1.11.1-1.11.11.2-1.21.2-1.2-1.11.1-0.8-0.60.9-0.9-0.91.2-1.2-0.2-0.2-0.5-1.01.11.20.80.9
Progressive ratio test 2 inactive lever presses0.10.20.60.5-0.50.4-0.40.50.6-0.60.6-0.6-0.50.5-0.3-0.20.2-0.2-0.20.7-0.7-0.2-0.2-0.1-0.40.40.30.20.2
Incentive Sensitization - Responses0.61.83.21.4-1.31.3-1.31.81.6-1.61.6-1.6-1.81.3-0.8-0.51.4-1.4-1.41.7-1.7-0.5-0.5-0.6-1.41.51.00.51.4
Incentive Sensitization - Breakpoint0.71.62.91.3-1.21.2-1.21.71.5-1.51.5-1.5-1.71.2-0.8-0.51.4-1.4-1.41.6-1.6-0.4-0.4-0.6-1.31.40.90.51.4
Sum of active levers in priming session hrs 5-60.10.10.30.40.10.1-0.1-0.10.1-0.10.1-0.10.1-0.2-0.5-0.60.5-0.5-0.50.1-0.10.10.1-0.4-0.30.10.40.40.3
Progressive ratio0.00.10.40.4-0.00.3-0.3-0.00.2-0.20.2-0.2-0.0-0.0-0.3-0.30.7-0.7-0.70.1-0.10.20.2-0.20.10.50.60.30.5
Food seeking constrained by brief footshock0.50.61.80.6-0.50.6-0.60.50.6-0.60.6-0.6-0.60.4-1.2-1.30.5-0.5-0.50.6-0.6-1.4-1.4-1.0-0.80.70.00.21.0
Seeking ratio, punishment vs. effort0.00.10.4-0.2-0.1-0.10.10.1-0.00.0-0.00.0-0.10.1-0.2-0.3-0.50.50.5-0.00.0-0.6-0.6-0.1-0.4-0.3-0.5-0.2-0.2
Retroperitoneal fat weight0.10.30.60.6-0.30.4-0.40.50.6-0.60.6-0.6-0.50.3-0.5-0.40.8-0.8-0.80.5-0.5-0.5-0.5-0.4-0.70.3-0.10.10.5
Reaction time number correct0.41.32.8-1.41.2-1.21.2-1.0-0.90.9-0.90.91.0-1.21.31.5-1.31.31.3-1.01.01.51.51.11.7-1.0-0.6-1.0-0.8
Reaction time mean minus median0.10.61.1-0.80.5-0.70.7-0.5-0.70.7-0.70.70.5-0.51.01.0-0.90.90.9-0.60.70.40.40.80.7-0.5-1.0-0.9-0.7
Reaction time mean minus median AUC0.00.10.2-0.20.1-0.20.20.0-0.20.2-0.20.2-0.0-0.10.40.4-0.30.30.3-0.10.1-0.1-0.10.20.4-0.1-0.4-0.4-0.2
Reaction time num false alarms0.40.71.50.6-0.30.5-0.50.81.1-1.11.1-1.1-0.90.2-0.7-0.50.9-0.9-0.91.1-1.1-0.7-0.7-0.9-0.20.80.30.11.2
Reaction time num false alarms AUC0.20.51.40.4-0.20.4-0.40.80.9-0.90.9-0.9-0.90.1-0.5-0.30.7-0.7-0.71.1-1.1-0.6-0.6-0.7-0.00.80.1-0.11.2
Reaction time trials correct on left0.41.32.8-1.41.2-1.21.2-1.0-0.90.9-0.90.91.0-1.21.31.5-1.31.31.3-1.01.01.51.51.11.7-1.0-0.6-1.0-0.8
Reaction time trials on left0.41.32.6-1.31.2-1.11.1-1.0-0.90.9-0.90.91.0-1.21.21.4-1.21.21.2-1.00.91.41.41.11.6-1.0-0.6-0.9-0.8
Reaction time mean0.20.41.10.4-1.00.8-0.80.40.4-0.40.4-0.4-0.31.1-0.5-0.7-0.20.20.20.8-0.7-0.6-0.6-0.5-1.00.80.91.00.2
Reaction time mean AUC0.20.41.30.4-1.00.8-0.80.30.4-0.40.4-0.4-0.31.1-0.6-0.8-0.20.20.20.8-0.7-0.6-0.6-0.6-1.00.71.01.10.1
Median of all reaction times1.01.53.11.0-1.61.5-1.50.91.1-1.11.1-1.1-0.91.7-1.2-1.40.3-0.3-0.31.4-1.4-1.1-1.1-1.2-1.61.41.61.80.7
Reaction time omissions0.40.61.10.5-0.90.8-0.80.80.8-0.80.8-0.8-0.80.8-0.7-0.90.4-0.4-0.41.1-1.1-0.9-0.9-0.8-0.80.80.60.80.7
Reaction time false alarm rate0.91.32.11.0-0.80.9-0.91.21.3-1.31.3-1.3-1.20.7-1.1-1.01.2-1.2-1.21.4-1.4-1.3-1.3-1.2-0.91.20.50.51.5
Reaction time premature initiation rate0.30.51.70.4-0.70.8-0.80.10.3-0.30.3-0.3-0.20.6-0.9-0.90.3-0.3-0.30.8-0.8-0.6-0.6-1.0-0.11.01.11.30.7
Reaction time premature initiations0.10.20.9-0.60.2-0.10.1-0.7-0.50.5-0.50.50.6-0.30.10.2-0.70.70.7-0.00.00.50.5-0.01.00.10.40.5-0.0
Std. dev. reaction times0.00.00.2-0.1-0.10.0-0.00.1-0.10.1-0.10.1-0.00.20.30.1-0.40.40.40.1-0.0-0.3-0.30.00.00.1-0.2-0.1-0.1
Reaction time trials completed0.41.32.6-1.31.2-1.11.1-1.0-0.90.9-0.90.91.0-1.21.21.4-1.21.21.2-1.00.91.41.41.11.6-1.0-0.6-0.9-0.8
Reaction time trials AUC0.41.22.6-1.31.1-1.11.1-0.9-0.90.9-0.90.90.9-1.11.31.5-1.21.21.2-0.90.91.51.51.21.6-1.0-0.6-0.9-0.8
Run reversals in cocaine runway, females1.51.73.6-1.30.8-1.01.0-1.6-1.41.4-1.41.41.6-0.71.21.1-1.71.71.7-1.11.11.41.41.31.0-1.6-0.0-0.1-1.9
Run reversals in cocaine runway, males0.20.20.40.5-0.40.4-0.40.50.4-0.40.4-0.4-0.50.4-0.4-0.20.6-0.6-0.60.5-0.50.00.00.0-0.40.30.20.10.2
Latency to leave start box in cocaine runway0.91.22.4-1.01.1-1.21.2-1.0-0.70.7-0.70.71.1-1.01.31.5-0.90.90.9-1.01.01.61.61.31.1-1.4-0.5-0.9-1.4
Latency to leave start box in cocaine runway, F1.92.35.7-1.61.5-1.51.5-1.6-1.21.2-1.21.21.6-1.41.61.8-1.41.41.4-1.31.32.42.41.81.7-1.6-0.5-0.9-1.6
Latency to leave start box in cocaine runway, M0.40.40.90.8-0.60.5-0.40.60.8-0.80.8-0.8-0.60.6-0.2-0.40.7-0.7-0.70.4-0.4-0.9-0.9-0.5-0.90.20.30.30.1
Std. dev. time between licks in bursts0.10.10.5-0.50.4-0.40.4-0.2-0.20.2-0.20.20.2-0.50.20.2-0.70.70.7-0.20.2-0.2-0.20.00.3-0.1-0.7-0.60.1
Total sessions with >9 infusions0.20.31.30.4-0.70.6-0.60.20.3-0.30.3-0.3-0.20.8-0.6-0.70.3-0.3-0.30.5-0.5-0.3-0.3-0.3-0.70.31.11.0-0.3
Short access day 1 total inactive lever presses1.32.63.51.7-1.61.6-1.61.71.8-1.81.8-1.8-1.61.6-1.5-1.71.7-1.7-1.71.9-1.9-1.6-1.6-1.5-1.51.21.31.31.0
Short access day 10 total inactive lever presses0.00.00.2-0.1-0.20.1-0.10.1-0.20.2-0.20.2-0.10.30.0-0.1-0.10.10.10.5-0.5-0.2-0.20.00.30.2-0.20.1-0.1
Short access day 1 total infusions0.40.72.50.9-0.90.8-0.90.30.8-0.80.8-0.8-0.20.9-1.1-1.20.8-0.8-0.80.7-0.7-0.4-0.4-0.7-1.00.31.61.5-0.1
Short access day 10 total infusions0.30.50.80.6-0.70.7-0.70.60.9-0.90.9-0.9-0.60.7-0.8-0.80.3-0.3-0.30.8-0.8-0.6-0.6-0.7-0.90.50.90.80.4
Short access total infusions0.30.51.80.6-0.80.7-0.80.30.7-0.70.7-0.7-0.30.8-0.9-0.90.4-0.4-0.40.8-0.8-0.2-0.2-0.6-0.70.41.31.20.1
Short access day 1 locomotion1.01.62.91.4-1.31.2-1.31.11.3-1.31.3-1.3-1.01.3-1.5-1.71.3-1.3-1.31.2-1.2-1.4-1.4-1.3-1.20.81.41.40.7
Short access day 10 total locomotion0.52.23.71.6-1.41.3-1.31.91.8-1.81.8-1.8-1.91.3-1.1-1.01.7-1.7-1.71.4-1.4-1.6-1.6-1.2-1.21.30.50.51.6
Short access total locomotion0.30.50.80.8-0.60.5-0.50.80.8-0.80.8-0.8-0.80.6-0.5-0.50.9-0.9-0.90.7-0.7-0.7-0.7-0.4-0.70.30.40.30.4
One hour access (0.3 mA shock)0.40.51.3-0.70.4-0.50.5-0.6-0.60.6-0.60.60.6-0.30.80.8-0.80.80.8-0.50.51.11.11.00.6-0.4-0.1-0.3-0.7
Compulsive drug intake0.20.21.5-0.4-0.2-0.10.1-0.4-0.50.5-0.50.50.50.40.30.3-0.50.50.5-0.60.60.40.40.6-0.1-0.40.20.3-1.2
One hour access (shock baseline)0.00.00.1-0.10.10.0-0.0-0.3-0.00.0-0.00.00.2-0.1-0.1-0.1-0.20.20.20.2-0.20.30.30.00.20.00.30.20.1
Social response proportion0.20.30.7-0.30.7-0.60.6-0.6-0.60.6-0.60.60.6-0.70.50.4-0.10.10.1-0.70.70.30.30.40.4-0.8-0.5-0.5-0.6
Social responses0.10.20.70.30.3-0.10.10.20.2-0.20.2-0.2-0.2-0.4-0.3-0.30.8-0.8-0.8-0.10.1-0.7-0.7-0.50.10.1-0.5-0.40.5
Social time0.20.31.7-0.50.8-0.60.6-0.1-0.30.3-0.30.30.0-0.90.40.6-0.20.20.2-0.20.2-0.0-0.00.11.00.0-1.3-1.30.4
Soleus weight0.10.41.6-0.31.0-0.70.7-0.1-0.50.5-0.50.50.0-1.20.20.20.4-0.4-0.4-0.20.20.30.30.11.0-0.1-1.2-1.30.6
Bone: stiffness0.00.10.2-0.20.4-0.20.1-0.5-0.00.0-0.00.00.4-0.4-0.3-0.2-0.10.10.1-0.20.10.30.3-0.20.4-0.10.40.20.2
Tibialis anterior weight1.65.67.3-2.52.7-2.52.5-2.6-2.32.3-2.32.32.5-2.72.22.1-2.42.42.4-2.52.42.22.22.02.4-2.3-2.1-2.2-2.0
Time to tail flick, vehicle, before self-admin0.20.21.50.00.0-0.10.10.70.1-0.10.1-0.1-0.7-0.10.10.20.1-0.1-0.10.3-0.3-0.8-0.8-0.10.00.0-1.2-1.10.4
Time to tail flick, vehicle, after self-admin0.00.10.4-0.10.10.0-0.00.10.0-0.00.0-0.0-0.1-0.20.20.2-0.00.00.0-0.00.00.20.20.10.10.5-0.5-0.50.6
Time to tail flick, test, before self-admin1.21.42.4-1.31.1-1.11.1-1.2-1.61.6-1.61.61.2-1.11.11.1-1.31.31.3-1.11.10.80.81.01.2-0.8-1.3-1.0-0.8
Time to tail flick, test, after self-admin0.30.30.80.40.1-0.10.10.70.6-0.60.6-0.6-0.7-0.2-0.20.00.7-0.7-0.70.4-0.4-0.9-0.9-0.5-0.00.2-0.9-0.70.6
Delta time to tail flick, vehicle, before/after SA0.20.21.30.3-0.10.4-0.40.30.5-0.50.5-0.5-0.4-0.1-0.4-0.20.6-0.6-0.60.4-0.40.10.1-0.50.10.90.20.21.2
Delta time to tail flick, test, before/after SA2.42.94.52.0-1.41.4-1.42.12.1-2.12.1-2.1-2.11.4-1.4-1.22.1-2.1-2.11.7-1.7-1.5-1.5-1.4-1.51.31.00.81.5
Tibia length1.74.88.4-2.32.8-2.62.6-2.3-2.02.0-2.02.02.2-2.91.92.1-1.81.81.8-2.22.11.91.91.72.8-2.3-2.4-2.4-1.6
Ambulatory time before self-admin0.00.00.3-0.1-0.00.1-0.1-0.10.1-0.10.1-0.10.10.1-0.2-0.1-0.10.10.10.2-0.20.30.30.0-0.00.20.50.30.1
Ambulatory time after self-admin1.01.62.4-1.51.5-1.41.4-1.5-1.31.3-1.31.31.5-1.60.70.6-1.41.41.4-1.21.20.50.50.81.2-1.3-1.5-1.3-1.1
Bone: tissue strength1.61.62.3-1.31.1-1.31.3-1.1-1.41.4-1.41.41.1-1.11.41.4-1.21.21.2-1.41.31.41.41.51.1-1.3-1.2-1.1-1.1
Total heroin consumption2.12.45.61.6-1.21.5-1.51.71.7-1.71.7-1.7-1.81.0-1.3-1.11.5-1.5-1.52.0-2.0-1.4-1.4-1.7-1.11.81.00.92.4
Bone: trabecular number4.68.711.32.9-2.52.8-2.82.93.0-3.03.0-3.0-2.92.3-3.2-3.23.3-3.3-3.33.1-3.1-3.1-3.1-3.4-2.33.02.12.23.3
Bone: trabecular spacing2.13.14.7-1.92.0-2.02.0-1.5-1.51.5-1.51.51.5-2.11.82.0-1.71.71.7-1.61.61.71.71.62.2-1.5-2.0-2.1-1.2
Bone: trabecular thickness0.10.10.20.3-0.20.3-0.30.40.4-0.40.4-0.4-0.40.2-0.3-0.40.3-0.3-0.30.3-0.4-0.5-0.5-0.4-0.10.30.00.10.4
Bone: trabecular tissue density0.10.30.70.3-0.60.3-0.3-0.1-0.60.6-0.60.60.20.70.3-0.0-0.30.30.3-0.40.40.50.50.6-0.8-0.30.70.8-0.8
Water consumed over 24 hours0.20.30.9-0.50.5-0.60.6-0.1-0.30.3-0.30.30.1-0.50.60.8-0.30.30.3-0.20.20.80.80.70.8-0.5-1.0-0.9-0.1
Number of responses in last shaping day0.30.41.00.6-0.90.7-0.70.60.4-0.40.4-0.4-0.51.0-0.8-0.90.5-0.5-0.50.6-0.6-1.0-1.0-0.6-0.90.40.50.7-0.2