Asb8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Asb8 0.06 0.05 4.8e-10 0.06 0.06 0.06 0.06 2.4e-09 6.8e-09 1.1e-09 3.5e-10
2 Liver isoform ratio XM_006242328.4 0.03 0.02 2.6e-03 0.01 0.01 0.01 0.01 1.2e-02 9.9e-03 1.4e-02 3.9e-02
3 PL intron excision ratio chr7_131148014_131150607 0.03 0.02 2.7e-03 0.02 0.02 0.01 0.02 2.0e-03 1.5e-03 9.7e-03 4.5e-03
4 Liver alternative TSS NM_001108109.2 0.02 0.02 7.7e-03 0.01 0 0 0 1.7e-02 8.1e-02 1.0e-01 1.3e-01
5 PL mRNA stability Asb8 0.03 0.02 2.7e-05 0.04 0.04 0.03 0.04 7.4e-05 2.6e-05 1.9e-04 6.3e-05
6 Brain alternative TSS XM_063263669.1 0.06 0.04 4.6e-06 0.05 0.05 0.04 0.05 2.6e-05 2.0e-05 2.1e-04 2.6e-05
7 Adipose mRNA stability Asb8 0.13 0.07 0.0e+00 0.17 0.16 0.15 0.17 1.7e-18 3.2e-17 9.0e-17 3.4e-18
8 Brain gene expression Asb8 0.04 0.03 2.1e-04 0.05 0.04 0.04 0.04 4.2e-05 1.7e-04 1.7e-04 1.7e-04
9 Liver gene expression Asb8 0.07 0.05 5.6e-08 0.06 0.06 0.04 0.06 1.5e-07 2.9e-07 1.0e-05 3.6e-07
10 Brain isoform ratio XM_063263669.1 0.05 0.03 1.8e-05 0.04 0.04 0.03 0.04 6.5e-05 1.1e-04 5.3e-04 1.4e-04
11 Adipose alternative TSS XM_063263669.1 0.04 0.03 2.2e-05 0.04 0.03 0.02 0.03 6.5e-05 1.7e-04 2.9e-03 9.2e-05
12 Adipose isoform ratio XM_063263669.1 0.04 0.03 6.1e-05 0.03 0.02 0.02 0.03 2.7e-04 9.7e-04 1.1e-03 4.7e-04
13 Brain mRNA stability Asb8 0.07 0.04 1.1e-08 0.09 0.09 0.09 0.09 1.7e-08 1.2e-08 2.1e-08 1.9e-08
14 Liver isoform ratio XM_017594890.3 0.02 0.02 5.8e-03 0.03 0.01 0.01 0.02 7.9e-04 2.0e-02 7.7e-03 4.8e-03
15 pVTA mRNA stability Asb8 0.11 0.07 1.8e-09 0.11 0.1 0.1 0.11 4.1e-09 3.7e-08 1.3e-08 3.5e-09
16 IC mRNA stability Asb8 0.12 0.09 2.9e-04 0.08 0.06 0.03 0.07 3.8e-04 1.4e-03 2.1e-02 7.5e-04
17 PL gene expression Asb8 0.02 0.02 9.2e-03 0.01 0.01 0 0.01 1.2e-02 1.2e-02 1.1e-01 1.7e-02
18 PL intron excision ratio chr7_131146345_131147851 0.06 0.05 6.1e-03 0 0.01 0.02 0.02 7.6e-02 2.1e-02 2.8e-03 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density8.714.917.8-4.24.14.1-4.0-3.83.7-3.94.0-4.04.03.93.9-3.7-3.9-3.9-3.1-3.1-3.9
Area under the delay curve1.11.32.0-1.41.21.2-1.3-1.11.2-1.11.1-1.11.11.31.3-1.1-0.8-1.0-0.6-0.7-1.4
BMI with tail7.024.126.9-4.75.25.2-5.1-5.05.0-5.15.1-5.14.95.15.1-4.9-4.9-4.9-4.2-4.0-4.6
BMI without tail2.26.88.5-2.92.62.6-2.6-2.62.7-2.72.8-2.82.52.72.7-2.6-2.8-2.7-2.5-2.2-1.9
Body weight7.532.735.6-5.76.06.0-5.9-5.85.9-5.95.8-5.85.85.95.9-5.7-5.7-5.8-5.1-4.9-5.1
Weight adjusted by age2.94.36.4-1.71.91.9-2.0-2.22.1-2.12.2-2.22.12.22.2-2.2-2.1-2.2-2.5-2.5-0.5
Bone surface10.418.921.6-4.64.64.6-4.5-4.44.3-4.54.4-4.44.54.54.5-4.3-4.4-4.4-3.6-3.7-4.0
Bone volume7.814.016.1-4.04.03.9-3.9-3.83.7-3.83.7-3.74.03.83.8-3.7-3.7-3.8-3.1-3.2-3.5
Breakpoint value in progressive ratio session1.11.32.6-1.61.11.1-1.0-1.11.1-1.01.2-1.21.30.80.8-1.1-1.3-0.9-1.2-1.1-1.1
Number of licking bursts0.10.22.30.2-0.5-0.50.20.3-0.40.10.0-0.0-0.3-0.1-0.10.20.00.1-0.3-0.41.5
Context. condit. distance diff. score0.50.51.0-0.70.70.7-0.6-0.70.7-0.60.9-0.90.60.60.6-0.8-1.0-0.8-0.8-0.8-0.5
Locomotion velocity, session 11.11.11.81.2-1.1-1.01.00.9-0.81.2-1.21.2-1.0-1.2-1.20.81.31.40.60.61.2
Locomotion distance, session 13.34.15.62.2-1.8-1.82.02.0-1.92.1-2.32.3-1.9-2.1-2.12.02.32.42.12.20.2
Locomotion velocity, session 20.50.61.50.8-0.5-0.50.70.6-0.60.9-0.90.9-0.6-0.9-0.90.61.01.20.70.7-0.2
Locomotion distance, session 22.94.05.72.0-1.7-1.71.91.9-1.92.1-2.32.3-2.0-2.1-2.12.02.32.42.12.20.4
Locomotion velocity, session 33.94.56.02.2-2.0-2.02.12.1-2.02.2-2.42.4-2.1-2.2-2.22.12.52.12.22.21.0
Locomotion distance, session 35.05.46.62.4-2.3-2.32.32.4-2.42.3-2.52.5-2.3-2.3-2.32.42.62.32.32.31.3
Stereotopy head waving bouts, day 30.91.02.0-1.01.01.0-1.1-1.11.0-1.00.9-0.91.11.01.0-1.2-0.7-0.8-1.4-1.3-0.2
Stereotopy head waving duration, day 30.30.30.8-0.50.60.6-0.7-0.70.6-0.40.4-0.40.70.40.4-0.7-0.3-0.2-0.9-0.8-0.1
Locomotion velocity, session 70.00.00.10.1-0.2-0.20.10.2-0.1-0.0-0.10.1-0.10.00.00.10.00.00.2-0.00.2
Locomotion distance, session 70.70.91.50.9-1.2-1.21.11.1-1.10.9-0.80.8-1.1-0.9-0.91.10.70.70.90.81.0
Stereotopy head waving bouts, day 71.41.53.4-0.91.11.1-1.1-1.31.3-1.11.3-1.31.31.11.1-1.4-1.3-1.1-1.8-1.70.2
Stereotopy head waving duration, day 71.01.32.4-0.71.01.1-1.1-1.31.2-1.01.1-1.11.11.01.0-1.3-1.1-1.0-1.5-1.40.2
Locomotion velocity, session 80.00.00.2-0.10.20.2-0.1-0.20.30.20.1-0.10.2-0.2-0.2-0.20.10.2-0.3-0.2-0.5
Locomotion distance, session 81.21.82.51.5-1.2-1.21.41.3-1.31.5-1.21.2-1.4-1.5-1.51.41.31.51.51.6-0.1
Degree of sensitization distance0.91.01.8-1.10.80.8-0.9-0.90.9-1.01.2-1.20.91.01.0-1.0-1.3-1.1-1.0-1.0-0.3
Degree of sensitization stereotypy0.30.41.1-0.10.40.4-0.4-0.60.6-0.40.6-0.60.50.40.4-0.7-0.7-0.4-1.0-0.90.8
Conditioned locomotion0.20.22.2-0.5-0.2-0.2-0.1-0.10.0-0.2-0.00.00.10.10.1-0.30.2-0.0-0.9-0.91.5
Cocaine response after cond. corrected0.20.33.10.20.30.3-0.00.00.10.3-0.20.20.0-0.2-0.20.20.30.20.90.9-1.8
Cocaine response after cond. not corrected1.01.12.51.2-0.7-0.71.01.0-1.01.2-0.90.9-0.9-1.1-1.11.11.01.11.61.5-0.8
Cocaine response before conditioning4.85.78.12.6-2.7-2.82.62.6-2.82.3-2.02.0-2.5-2.3-2.32.51.92.31.81.82.6
Saline control response0.00.00.1-0.2-0.1-0.20.10.2-0.30.10.2-0.2-0.1-0.1-0.10.3-0.10.00.20.2-0.2
Bone: connectivity density5.78.911.3-3.43.23.2-3.1-3.02.9-3.03.1-3.13.13.03.0-2.9-3.0-3.0-2.2-2.3-3.2
Bone: cortical apparent density0.30.41.30.4-0.8-0.80.60.7-0.70.7-0.50.5-0.7-0.7-0.70.60.40.50.30.21.2
Bone: cortical area11.417.520.2-4.54.34.3-4.3-4.34.3-4.24.2-4.24.44.24.2-4.3-4.2-4.2-4.0-4.0-3.1
Bone: cortical porosity1.61.72.11.4-1.4-1.41.31.4-1.51.3-1.41.4-1.3-1.2-1.21.31.31.31.01.01.2
Bone: cortical porosity1.81.92.41.5-1.5-1.51.51.5-1.51.4-1.51.5-1.4-1.3-1.31.41.31.31.01.01.4
Bone: cortical thickness5.08.210.2-3.23.13.0-3.1-3.02.9-2.82.7-2.73.12.82.8-3.0-2.7-2.8-2.8-2.7-2.3
Bone: cortical thickness0.40.50.7-0.80.80.8-0.7-0.70.7-0.70.7-0.70.80.60.6-0.7-0.8-0.7-0.6-0.5-0.8
Bone: cortical tissue density0.40.51.50.5-0.9-0.90.70.8-0.80.8-0.60.6-0.8-0.8-0.80.70.50.60.40.31.2
Condit. Reinf. active minus inactive responses0.20.30.60.4-0.2-0.20.30.4-0.30.4-0.80.8-0.3-0.4-0.40.40.60.60.70.7-0.5
Condit. Reinf. active-inactive response ratio0.10.11.3-0.30.50.5-0.3-0.30.3-0.1-0.10.10.30.10.1-0.2-0.1-0.10.10.2-1.1
Condit. Reinf. active responses0.70.91.71.0-0.7-0.70.80.9-0.90.8-1.31.3-0.9-0.8-0.80.91.21.31.11.10.1
Condit. Reinf. inactive responses2.53.03.82.0-1.8-1.81.81.8-1.91.5-1.71.7-1.8-1.5-1.51.81.81.91.51.61.6
Incentive salience index mean0.00.10.4-0.20.30.3-0.3-0.20.2-0.2-0.20.20.20.20.2-0.10.10.00.00.1-0.6
Condit. Reinf. lever presses0.30.40.7-0.60.70.7-0.8-0.60.6-0.90.2-0.20.70.90.8-0.6-0.2-0.4-0.5-0.5-0.6
Condit. Reinf. active minus inactive responses0.00.00.20.3-0.3-0.20.20.2-0.10.0-0.00.0-0.2-0.1-0.10.1-0.00.00.10.10.4
Condit. Reinf. active-inactive response ratio0.30.30.60.8-0.5-0.50.60.5-0.50.5-0.60.6-0.6-0.5-0.50.50.60.70.70.60.2
Condit. Reinf. active responses0.20.30.60.6-0.7-0.70.60.6-0.60.4-0.30.3-0.6-0.5-0.50.60.20.30.50.40.8
Condit. Reinf. inactive responses0.60.82.50.8-1.1-1.11.01.0-1.10.9-0.60.6-1.0-0.9-0.90.90.40.60.50.51.6
Condit. Reinf. lever presses0.00.00.2-0.20.10.1-0.0-0.0-0.0-0.10.4-0.40.10.10.10.0-0.5-0.30.10.1-0.4
Condit. Reinf. lever reinforcers received0.40.60.90.9-0.9-0.90.90.9-0.90.7-0.60.6-0.9-0.8-0.80.90.40.50.70.70.9
Conditioned reinforcement - actives0.50.91.21.0-1.0-1.00.91.0-0.90.9-1.11.1-0.8-0.9-0.90.91.10.70.80.71.0
Conditioned reinforcement - inactives2.74.05.21.9-2.0-2.02.02.0-1.92.0-2.32.3-2.0-2.0-2.02.02.21.92.01.91.4
Conditioned locomotion0.20.21.70.3-0.6-0.60.40.4-0.40.4-0.30.3-0.4-0.4-0.40.30.20.10.0-0.01.3
Patch foraging indifference point 0 sec1.52.73.61.6-1.7-1.71.91.7-1.71.4-1.81.8-1.8-1.4-1.41.71.61.41.91.91.1
Patch foraging indifference point AUC0.81.11.61.2-1.2-1.21.11.1-1.11.1-0.70.7-1.2-1.1-1.11.00.90.91.10.91.3
Delay disc. indifference point, 0s delay1.21.32.0-1.41.21.2-1.4-1.31.3-1.01.0-1.01.01.11.1-1.3-0.8-1.2-1.1-1.2-0.4
Delay disc. indifference point, 16s delay1.31.42.2-1.51.21.2-1.3-1.21.3-1.31.1-1.11.11.51.5-1.2-1.0-1.1-1.0-1.1-0.9
Delay disc. indifference point, 2s delay0.91.01.3-1.01.01.0-1.0-1.01.0-0.91.1-1.11.10.90.9-1.0-0.9-0.8-1.0-1.0-0.7
Delay disc. indifference point, 24s delay1.31.41.9-1.31.11.1-1.2-1.21.2-1.31.2-1.21.21.41.4-1.2-1.1-1.2-1.0-1.0-0.7
Delay disc. indifference point, 4s delay0.50.62.6-0.90.90.9-0.8-0.60.7-0.70.6-0.60.60.80.8-0.5-0.5-0.6-0.0-0.2-1.6
Delay disc. indifference point, 8s delay2.63.04.6-2.01.91.9-1.9-1.81.8-1.61.7-1.71.71.91.9-1.7-1.4-1.6-1.2-1.2-2.1
Indifference point function ln k2.84.96.3-2.42.22.2-2.2-2.32.3-2.52.1-2.12.12.42.4-2.3-2.2-2.1-2.2-2.2-1.2
Indifference point function log k2.84.96.3-2.42.22.2-2.2-2.32.3-2.52.1-2.12.12.42.4-2.3-2.2-2.1-2.2-2.2-1.2
Patch foraging total patch changes 0 sec1.42.73.41.5-1.7-1.71.81.7-1.71.4-1.81.8-1.8-1.4-1.41.71.51.41.81.81.3
Patch foraging total patch changes 12 sec1.82.32.81.5-1.7-1.61.71.6-1.51.6-1.51.5-1.6-1.6-1.61.51.51.41.41.31.5
Patch foraging total patch changes 18 sec3.24.96.42.1-2.5-2.52.32.3-2.22.1-2.02.0-2.5-2.0-2.02.22.11.82.31.92.5
Patch foraging total patch changes 24 sec1.11.93.91.4-1.6-1.61.51.4-1.31.2-1.41.4-1.6-1.1-1.11.31.41.01.11.12.0
Patch foraging total patch changes 6 sec2.33.54.51.9-2.0-2.02.12.0-2.01.9-1.81.8-1.9-1.8-1.82.01.71.71.91.81.2
Patch foraging time to switch 0 sec2.04.05.12.2-2.1-2.12.12.1-2.22.2-1.81.8-1.8-2.3-2.32.11.92.11.51.51.5
Patch foraging water rate 0 sec2.96.28.2-2.92.62.6-2.7-2.62.8-2.72.2-2.22.42.72.7-2.7-2.2-2.5-2.2-2.2-1.5
Patch foraging water rate 12 sec2.45.05.9-2.42.32.3-2.3-2.32.4-2.22.2-2.22.22.42.4-2.4-2.4-2.3-2.3-2.2-1.2
Patch foraging water rate 18 sec0.50.81.1-0.80.90.9-0.9-1.01.0-1.10.7-0.70.91.01.0-0.9-1.0-1.0-0.9-0.7-0.5
Patch foraging water rate 24 sec2.94.15.6-2.11.91.9-2.1-2.12.1-2.12.0-2.02.02.12.1-2.2-2.0-2.0-2.4-2.3-0.6
Patch foraging water rate 6 sec4.46.47.7-2.62.62.6-2.6-2.72.7-2.82.2-2.22.52.72.7-2.7-2.4-2.5-2.6-2.5-1.5
Seeking ratio, delayed vs. immediate footshock0.20.32.9-0.10.60.6-0.4-0.30.4-0.10.3-0.30.50.10.1-0.2-0.0-0.00.40.3-1.7
Distance traveled before self-admin0.60.82.00.8-1.0-1.00.90.8-0.80.8-1.01.0-0.9-0.8-0.80.70.80.80.40.51.4
Distance traveled after self-admin0.30.30.80.3-0.4-0.40.40.5-0.50.5-0.80.8-0.7-0.4-0.40.60.70.70.80.9-0.3
Extensor digitorum longus weight5.120.223.8-4.64.64.6-4.6-4.84.9-4.64.4-4.44.54.64.6-4.8-4.6-4.6-4.3-4.3-2.7
Bone: elastic displacement5.05.86.72.3-2.5-2.52.32.4-2.42.5-2.62.6-2.4-2.5-2.52.42.52.52.22.11.8
Bone: elastic work0.10.10.20.1-0.3-0.30.10.3-0.30.3-0.50.5-0.2-0.3-0.30.20.40.10.20.10.2
Bone: endosteal estimation7.215.817.5-4.14.04.0-3.9-4.14.1-4.14.2-4.24.04.14.1-4.1-4.2-4.0-3.8-3.8-2.5
Bone: endosteal perimeter7.215.318.4-4.04.04.0-3.9-4.04.0-3.94.1-4.14.04.04.0-4.0-4.3-4.0-3.7-3.6-2.9
Epididymis fat weight0.93.04.3-1.71.81.8-1.9-1.82.0-2.11.5-1.51.72.02.0-1.8-1.3-1.5-1.2-1.4-1.4
Delta time in closed arm before/after self-admin0.10.10.60.4-0.1-0.10.30.3-0.30.2-0.10.1-0.2-0.2-0.20.40.20.40.50.6-0.8
Delta time in open arm before/after self-admin0.80.81.30.6-1.0-1.00.80.9-0.90.9-1.01.0-0.9-0.9-0.90.80.90.90.60.51.1
Diff in mean of infusions in LGA sessions0.70.91.6-0.91.01.0-0.9-0.90.9-0.90.9-0.91.30.80.8-0.9-0.8-0.6-1.1-1.0-1.3
Delay discount exponential model param1.01.11.91.4-1.1-1.21.21.0-1.11.0-1.01.0-1.0-1.2-1.21.00.80.90.60.71.4
Extinction: sum of active levers before priming1.21.32.5-1.41.11.1-1.2-1.31.2-1.01.0-1.01.11.01.0-1.3-1.0-1.2-1.6-1.3-0.4
Active lever presses in extinction session 61.11.12.0-1.41.21.2-1.1-1.11.1-1.00.8-0.81.11.01.0-1.0-1.1-1.0-0.8-0.8-1.3
Bone: final force10.015.918.3-4.24.34.3-4.2-4.24.2-4.13.8-3.84.24.14.1-4.1-3.7-3.9-3.5-3.5-3.5
Bone: final moment10.316.619.1-4.34.44.4-4.3-4.24.3-4.23.9-3.94.34.14.1-4.2-3.8-3.9-3.5-3.5-3.7
Food consumed during 24 hour testing period1.21.74.3-1.21.51.5-1.3-1.21.2-1.11.4-1.41.31.11.1-1.1-1.4-1.2-0.7-0.7-2.1
Glucose0.40.61.0-0.90.60.6-0.7-0.70.7-0.70.9-0.90.70.80.8-0.7-1.0-1.0-0.8-0.8-0.1
Heart weight0.10.10.5-0.40.40.4-0.3-0.40.4-0.20.7-0.70.30.20.2-0.4-0.4-0.2-0.2-0.1-0.5
Delay discount hyperbolic model param0.91.02.01.3-1.1-1.11.11.0-1.00.9-1.01.0-1.0-1.1-1.10.90.70.80.50.61.4
Intermittent access intake day 1-15 change0.00.00.4-0.00.00.00.00.1-0.10.20.2-0.20.0-0.2-0.20.20.00.00.40.2-0.6
Intermittent access intake escalation0.00.10.6-0.20.30.3-0.3-0.10.2-0.20.3-0.30.20.10.1-0.1-0.2-0.30.20.1-0.8
Intermittent access intake escalation 20.10.10.40.3-0.0-0.00.10.2-0.10.2-0.10.1-0.0-0.2-0.20.30.10.10.40.3-0.6
Intermitt. access day 1 inactive lever presses0.51.98.41.2-1.7-1.71.41.3-1.41.2-1.21.2-1.5-1.2-1.21.10.91.00.50.62.9
Intermitt. access day 15 inactive lever presses0.61.31.91.1-1.2-1.21.21.2-1.21.0-0.90.9-1.4-1.1-1.11.11.11.11.01.21.2
Intermitt. access escalation Index0.60.81.2-0.70.80.8-0.8-0.90.8-1.01.1-1.10.81.01.0-0.9-1.1-1.0-0.9-0.8-0.5
Intermittent access day 1 total infusions0.71.11.71.3-1.0-1.01.11.1-1.10.9-1.21.2-1.0-0.9-0.91.11.10.91.01.10.4
Intermittent access day 15 total infusions0.30.40.80.9-0.7-0.70.70.7-0.70.5-0.70.7-0.7-0.5-0.50.70.70.40.60.70.4
Intermittent access terminal intake (last 3 days)0.71.01.41.2-1.0-1.01.01.1-1.00.9-1.11.1-0.9-0.9-0.91.11.00.71.00.90.5
Intermittent access total infusions1.01.11.61.2-1.1-1.11.11.1-1.11.0-1.31.3-1.1-1.0-1.01.11.10.91.00.90.8
Intermittent access day 1 locomotion0.10.11.30.4-0.4-0.40.20.2-0.10.1-0.30.3-0.3-0.0-0.00.10.1-0.3-0.0-0.21.1
Intermittent access day 15 total locomotion0.10.11.80.3-0.4-0.40.00.2-0.10.0-0.10.1-0.1-0.0-0.00.1-0.1-0.4-0.2-0.41.3
Intermittent access total locomotion0.70.84.00.9-1.1-1.10.80.8-0.70.6-1.01.0-1.0-0.6-0.60.70.70.20.40.32.0
Intermittent access standard deviation0.10.20.40.5-0.4-0.40.60.5-0.50.6-0.40.4-0.3-0.6-0.60.60.40.60.50.5-0.2
Left kidney weight1.04.814.8-2.22.62.6-2.3-2.22.4-2.21.6-1.62.32.22.2-2.0-1.7-1.8-1.2-1.1-3.8
Right kidney weight4.520.623.9-4.64.84.8-4.7-4.74.9-4.84.2-4.24.74.84.8-4.6-4.2-4.5-4.0-4.0-4.1
Cocaine induced anxiety3.04.25.4-1.82.02.0-2.0-2.12.0-2.12.3-2.32.22.12.1-2.1-2.3-2.1-2.2-2.1-1.1
Post-drug Anxiety3.43.64.6-2.11.91.9-1.9-1.91.9-1.92.2-2.21.91.91.9-1.9-1.9-1.9-1.7-1.6-1.5
Baseline Anxiety0.10.11.0-1.00.30.3-0.4-0.30.4-0.3-0.10.10.00.30.3-0.20.2-0.00.10.2-0.6
Tail length0.00.20.6-0.80.30.3-0.2-0.30.4-0.50.5-0.50.20.50.5-0.3-0.6-0.5-0.5-0.3-0.2
Length with tail1.98.29.1-3.03.03.0-2.9-2.93.0-3.02.7-2.72.93.03.0-2.9-2.8-2.9-2.7-2.6-2.4
Length without tail6.019.223.5-4.24.84.8-4.7-4.64.7-4.64.0-4.04.54.64.6-4.4-4.0-4.3-3.4-3.6-4.7
Times rat made contact with spout0.10.10.60.10.20.2-0.1-0.10.20.1-0.30.3-0.0-0.0-0.0-0.00.30.20.40.4-0.8
Lifetime Intake1.11.42.01.3-1.2-1.21.21.2-1.21.1-1.41.4-1.2-1.1-1.11.21.31.01.11.10.8
Liver weight, left9.816.218.9-4.34.14.1-4.1-4.03.9-4.04.2-4.24.24.04.0-4.0-4.2-4.0-3.9-3.9-3.2
Liver weight, right2.64.55.8-2.22.12.1-2.2-2.22.2-2.42.0-2.02.02.32.3-2.2-2.1-2.4-1.8-1.8-1.5
Locomotor activity0.81.32.11.4-1.3-1.31.21.2-1.21.0-1.31.3-1.1-1.0-1.01.11.21.10.70.91.1
Locomotor testing distance2.03.64.62.0-2.1-2.12.02.0-2.01.7-2.12.1-1.9-1.7-1.71.91.91.81.41.52.0
Locomotor testing rearing1.53.05.31.7-2.1-2.11.91.9-2.01.4-1.61.6-1.9-1.5-1.51.81.41.41.21.22.3
Locomotion in novel chamber1.41.82.4-1.11.41.4-1.4-1.41.5-1.51.2-1.21.21.41.4-1.5-1.3-1.1-1.5-1.6-0.8
Locomotion in novel chamber post-restriction0.00.00.20.00.20.2-0.3-0.20.4-0.1-0.30.30.10.10.1-0.20.3-0.10.3-0.1-0.2
Fecal boli incidents, locomotor time 11.21.73.60.7-0.7-0.71.01.1-0.91.2-1.91.9-1.0-1.1-1.11.31.61.21.71.8-1.2
Change in fecal boli incidents, locomotor task0.50.51.0-0.80.60.6-0.7-0.70.7-0.80.8-0.80.80.80.8-0.8-0.5-0.6-0.9-1.0-0.0
Time >=10cm from walls, locomotor time 10.30.31.1-1.00.60.6-0.7-0.50.6-0.50.3-0.30.40.50.5-0.4-0.2-0.60.10.0-1.1
Bouts of movement, locomotor time 10.10.10.7-0.30.40.4-0.5-0.30.4-0.4-0.40.40.40.30.3-0.20.30.0-0.1-0.1-0.8
Total resting periods, locomotor time 10.20.21.00.1-0.2-0.10.10.3-0.20.2-1.01.0-0.1-0.3-0.30.40.80.60.40.4-0.5
Rest time, locomotor task time 10.20.31.0-0.0-0.1-0.10.10.3-0.20.5-1.01.0-0.1-0.5-0.50.40.80.60.80.5-0.7
Distance moved, locomotor task time 10.10.20.50.7-0.3-0.30.40.2-0.40.20.7-0.7-0.2-0.4-0.40.2-0.4-0.0-0.3-0.10.6
Vertical activity count, locomotor time 10.71.63.0-1.11.31.3-1.1-1.21.1-1.21.7-1.71.31.21.2-1.1-1.4-1.1-0.9-0.9-1.6
Time >=10cm from walls, locomotor time 20.30.51.20.3-0.6-0.60.60.6-0.60.7-1.11.1-0.5-0.7-0.70.61.10.70.70.60.3
Bouts of movement, locomotor time 22.33.75.6-2.01.81.8-1.9-2.02.0-2.11.8-1.82.12.12.1-2.0-1.6-1.8-2.2-2.4-0.4
Total resting periods, locomotor time 22.34.05.9-2.11.81.8-2.0-2.02.1-2.22.0-2.02.12.22.2-2.1-1.7-2.0-2.3-2.4-0.4
Rest time, locomotor task time 20.10.20.4-0.70.40.4-0.4-0.30.4-0.40.0-0.00.50.50.5-0.3-0.2-0.4-0.1-0.4-0.6
Distance moved, locomotor task time 20.30.40.80.9-0.6-0.60.60.6-0.60.6-0.20.2-0.6-0.8-0.80.60.40.70.20.60.5
Vertical activity count, locomotor time 20.10.20.4-0.60.40.4-0.4-0.40.5-0.50.6-0.60.20.40.4-0.5-0.5-0.6-0.4-0.3-0.1
Light reinforcement 11.84.58.81.9-2.6-2.62.42.3-2.42.1-1.91.9-2.2-2.0-2.02.21.71.61.41.33.0
Light reinforcement 20.50.81.10.7-1.0-1.01.01.0-1.01.1-0.90.9-0.8-1.0-1.01.00.90.90.60.70.6
Bone: marrow area7.115.517.3-4.14.04.0-3.9-4.14.1-4.04.1-4.13.94.14.1-4.1-4.2-4.0-3.8-3.7-2.5
Bone: maximum diameter4.89.010.1-3.13.13.1-3.0-3.23.2-3.03.1-3.13.13.03.0-3.1-3.1-3.0-2.9-2.9-2.0
Bone: maximum force13.724.427.1-5.25.15.1-5.1-5.15.0-5.15.0-5.05.15.15.1-5.0-4.9-5.0-4.6-4.5-3.7
Bone: maximum moment14.024.627.5-5.25.15.1-5.1-5.15.0-5.15.0-5.05.15.15.1-5.0-4.9-5.1-4.5-4.5-3.9
Mean time between licks in bursts0.20.50.80.8-0.8-0.80.70.8-0.80.7-0.60.6-0.6-0.8-0.80.80.90.90.60.50.6
Mean num. licks in bursts0.30.43.30.20.20.20.10.10.00.4-0.70.7-0.1-0.3-0.30.30.60.51.01.0-1.8
Cd content in liver0.60.71.40.7-0.7-0.70.80.9-0.80.7-0.90.9-0.9-0.6-0.60.90.80.81.21.2-0.3
Co content in liver0.00.00.1-0.20.00.0-0.20.0-0.1-0.30.1-0.10.20.20.20.0-0.1-0.2-0.1-0.2-0.2
Cu content in liver1.72.03.1-1.41.71.7-1.5-1.61.6-1.50.9-0.91.61.61.6-1.5-0.9-1.0-1.2-1.2-1.8
Fe content in liver1.51.82.61.5-1.3-1.31.41.3-1.41.4-1.31.3-1.3-1.3-1.31.31.61.51.21.20.9
K content in liver0.40.30.7-0.60.70.7-0.6-0.70.8-0.60.2-0.20.50.70.7-0.7-0.3-0.5-0.4-0.5-0.7
Mg content in liver0.10.10.20.1-0.0-0.00.00.1-0.00.2-0.50.5-0.1-0.1-0.10.10.40.40.30.3-0.3
Mn content in liver0.10.11.10.1-0.3-0.30.20.00.1-0.0-0.40.4-0.20.10.1-0.10.40.1-0.1-0.21.0
Na content in liver0.10.10.5-0.10.00.1-0.0-0.20.2-0.00.1-0.10.1-0.0-0.0-0.3-0.2-0.1-0.3-0.40.7
Rb content in liver0.10.10.2-0.20.40.4-0.4-0.40.4-0.30.3-0.30.40.40.4-0.40.1-0.2-0.4-0.4-0.3
Se content in liver0.91.11.71.1-1.1-1.01.11.1-1.00.9-1.21.2-1.1-0.8-0.81.11.31.11.21.10.6
Sr content in liver2.21.93.0-1.71.31.3-1.5-1.41.4-1.51.1-1.11.31.41.4-1.4-1.6-1.7-1.3-1.4-0.6
Zn content in liver0.50.51.00.7-0.7-0.70.60.6-0.50.6-1.01.0-0.8-0.7-0.70.60.70.80.60.70.7
Bone: minimum diameter9.316.918.8-4.34.14.1-4.2-4.24.1-4.24.2-4.24.24.24.2-4.2-4.3-4.2-4.0-4.0-2.6
Time in familiar zone, hab. session 10.50.51.00.6-0.4-0.40.60.5-0.50.8-0.70.7-0.6-0.8-0.80.60.91.00.80.8-0.4
Time in novel zone, hab. session 10.50.51.1-0.50.30.3-0.6-0.50.4-0.70.7-0.70.50.70.7-0.6-0.8-0.8-1.0-1.00.8
Total zone transitions, hab. session 10.30.40.50.7-0.7-0.70.60.6-0.60.6-0.60.6-0.7-0.6-0.60.60.70.70.40.40.6
Total locomotion distance, hab. session 10.00.00.10.3-0.1-0.10.10.2-0.20.0-0.20.2-0.1-0.0-0.00.20.20.20.10.2-0.3
Locomotion velocity, hab. session 10.00.00.00.10.00.0-0.00.0-0.1-0.1-0.10.1-0.00.10.10.10.00.00.00.1-0.2
Time in familiar zone, hab. session 20.10.11.1-0.60.50.4-0.4-0.30.2-0.10.3-0.30.40.10.1-0.2-0.1-0.20.0-0.0-1.0
Time in novel zone, hab. session 20.20.22.70.5-0.6-0.60.50.2-0.20.1-0.20.2-0.4-0.1-0.10.1-0.10.1-0.3-0.31.6
Total zone transitions, hab. session 20.20.30.70.4-0.3-0.30.40.4-0.30.5-0.80.8-0.5-0.5-0.50.50.90.80.70.7-0.3
Total locomotion distance, hab. session 20.20.30.50.3-0.3-0.30.40.4-0.40.5-0.70.7-0.4-0.5-0.50.50.70.70.60.7-0.5
Locomotion velocity, hab. session 20.10.10.50.1-0.1-0.10.20.2-0.20.2-0.50.5-0.2-0.2-0.20.30.60.50.50.6-0.7
Novel to familiar place preference ratio2.12.33.8-1.31.21.1-1.3-1.31.2-1.61.9-1.91.41.61.6-1.4-2.0-1.7-1.8-1.8-0.2
Novelty place preference1.61.73.1-1.00.90.9-1.1-1.11.0-1.41.7-1.71.21.41.4-1.2-1.8-1.5-1.6-1.60.1
Time in novel zone, NPP test1.41.52.9-0.90.70.7-1.0-0.90.8-1.31.6-1.61.11.31.3-1.1-1.7-1.5-1.6-1.60.4
Total zone transitions, NPP test1.21.72.91.0-1.0-1.01.11.2-1.21.3-1.61.6-1.2-1.3-1.31.31.71.61.41.5-0.0
Total locomotion distance, NPP test1.92.63.51.4-1.5-1.61.51.7-1.71.6-1.91.9-1.6-1.6-1.61.71.81.81.71.80.5
Locomotion velocity, NPP test1.01.52.21.0-1.0-1.01.11.2-1.21.1-1.51.5-1.1-1.1-1.11.31.41.41.31.4-0.1
Intraocular pressure7.611.013.93.5-3.6-3.63.43.6-3.73.2-3.33.3-3.3-3.2-3.23.53.23.42.82.82.9
Delta distance traveled before/after self-admin0.10.11.6-0.30.20.2-0.10.00.00.1-0.00.0-0.0-0.0-0.00.10.20.10.60.6-1.3
Delta ambulatory time before/after self-admin0.00.00.4-0.20.00.0-0.00.1-0.10.1-0.00.0-0.1-0.1-0.10.20.20.10.40.4-0.6
Parametrial fat weight0.51.21.90.9-1.1-1.01.11.0-0.91.1-1.21.2-1.1-1.1-1.11.11.40.91.21.20.6
Pavlov. Cond. lever latency0.00.00.30.3-0.2-0.10.20.00.00.30.0-0.0-0.2-0.3-0.3-0.00.10.1-0.1-0.10.6
Pavlov. Cond. magazine entry latency0.10.10.6-0.3-0.0-0.10.10.2-0.2-0.1-0.20.2-0.20.10.10.30.10.00.50.6-0.8
Pavlov. Cond. change in total contacts0.10.10.3-0.50.30.3-0.3-0.30.2-0.50.4-0.40.30.50.5-0.2-0.5-0.2-0.4-0.2-0.5
Pavlov. Cond. index score0.30.40.8-0.90.60.5-0.6-0.50.4-0.80.4-0.40.60.80.8-0.4-0.6-0.7-0.4-0.3-0.7
Pavlov. Cond. latency score0.20.30.7-0.80.50.5-0.6-0.40.4-0.80.4-0.40.50.80.8-0.4-0.5-0.6-0.3-0.2-0.8
Pavlov. Cond. lever contacts0.10.10.20.1-0.3-0.30.30.4-0.50.2-0.30.3-0.3-0.2-0.20.40.10.30.40.40.0
Pavlov. Cond. magazine entry number0.10.10.50.5-0.2-0.20.20.1-0.10.4-0.00.0-0.1-0.4-0.40.00.20.3-0.1-0.20.7
Pavlov. Cond. intertrial magazine entries0.70.81.91.0-0.7-0.70.80.8-0.80.9-1.11.1-0.7-0.9-0.90.81.31.40.80.8-0.2
Pavlov. Cond. lever-magazine prob. diff.0.50.71.2-1.10.80.8-0.8-0.70.7-1.00.6-0.60.81.01.0-0.7-0.8-0.9-0.6-0.5-0.9
Pavlov. Cond. response bias0.10.10.3-0.1-0.1-0.10.20.3-0.30.0-0.30.3-0.2-0.0-0.00.30.10.20.40.5-0.5
Pavlov. Cond. lever latency0.10.10.2-0.00.20.3-0.2-0.40.4-0.30.1-0.10.20.30.3-0.4-0.1-0.2-0.4-0.30.2
Pavlov. Cond. magazine entry latency0.70.91.4-1.10.90.9-0.9-0.80.7-0.81.2-1.21.00.80.8-0.8-1.2-0.9-0.9-0.9-0.8
Pavlov. Cond. change in total contacts1.72.83.8-1.91.71.7-1.7-1.51.3-1.61.9-1.91.81.61.6-1.5-2.0-1.7-1.4-1.4-1.9
Pavlov. Cond. index score0.60.81.3-1.10.90.9-0.9-0.80.7-0.81.1-1.11.00.80.8-0.8-1.2-1.0-0.8-0.8-0.9
Pavlov. Cond. latency score0.60.71.1-1.10.80.8-0.9-0.70.6-0.81.0-1.00.90.80.8-0.7-1.0-0.9-0.7-0.7-0.9
Pavlov. Cond. lever contacts0.00.00.1-0.2-0.0-0.1-0.00.2-0.20.10.0-0.00.1-0.1-0.10.2-0.1-0.00.20.1-0.4
Pavlov. Cond. magazine entry number2.32.93.71.8-1.6-1.61.71.6-1.51.7-1.91.9-1.8-1.7-1.71.61.91.81.71.71.2
Pavlov. Cond. intertrial magazine entries5.27.810.23.0-2.6-2.62.82.7-2.42.8-3.23.2-2.9-2.7-2.72.73.12.93.02.91.5
Pavlov. Cond. lever-magazine prob. diff.0.81.11.8-1.21.01.0-1.1-0.90.8-0.91.3-1.31.10.90.9-0.9-1.3-1.1-1.0-1.0-1.0
Pavlov. Cond. response bias0.10.10.3-0.40.30.2-0.3-0.10.0-0.10.4-0.40.40.20.2-0.1-0.5-0.3-0.2-0.2-0.5
Time in closed arm before self-admin2.32.94.1-1.81.51.5-1.6-1.71.5-1.72.0-2.01.71.71.7-1.7-2.0-1.7-1.8-1.8-0.5
Time in closed arm after self-admin0.10.10.3-0.50.20.2-0.2-0.20.2-0.30.6-0.60.20.20.2-0.2-0.4-0.2-0.2-0.3-0.1
Time in open arm before self-admin0.00.00.20.3-0.2-0.20.00.10.0-0.1-0.30.3-0.10.10.10.00.0-0.3-0.2-0.10.5
Time in open arm after self-admin0.10.10.20.4-0.2-0.20.10.1-0.10.2-0.40.4-0.2-0.2-0.20.10.10.2-0.1-0.10.5
Bone: periosteal estimation12.726.929.7-5.55.35.3-5.3-5.45.3-5.25.3-5.35.35.35.3-5.3-5.3-5.2-4.9-4.9-3.6
Bone: periosteal perimeter10.918.821.6-4.64.64.6-4.4-4.54.6-4.34.3-4.34.54.34.3-4.4-4.4-4.3-3.8-3.8-3.8
Bone: post-yield work7.911.614.1-3.63.33.3-3.3-3.53.5-3.53.7-3.73.33.43.4-3.6-3.6-3.5-3.5-3.4-1.4
Progressive ratio test 1 active lever presses3.44.26.32.0-2.3-2.32.02.1-2.11.9-2.32.3-2.2-1.9-1.92.02.01.51.61.62.5
Progressive ratio test 1 breakpoint3.03.75.91.9-2.2-2.21.92.0-1.91.8-2.22.2-2.0-1.7-1.71.91.81.41.51.52.4
Progressive ratio test 1 inactive lever presses1.21.73.11.4-1.5-1.51.21.3-1.21.1-1.51.5-1.5-1.0-1.01.21.30.91.01.11.8
Progressive ratio test 2 active lever presses1.01.13.51.2-1.3-1.31.01.0-1.00.9-1.21.2-1.0-0.9-0.91.01.00.60.50.61.9
Progressive ratio test 2 breakpoint0.91.03.51.2-1.2-1.20.91.0-1.00.9-1.11.1-1.0-0.9-0.90.90.90.50.40.51.9
Progressive ratio test 2 inactive lever presses0.81.22.61.4-1.3-1.31.21.1-1.11.1-1.21.2-1.1-1.0-1.01.01.00.70.60.71.6
Incentive Sensitization - Responses0.30.51.0-0.50.60.6-0.7-0.70.7-0.60.6-0.60.80.60.6-0.7-0.5-0.9-1.0-0.7-0.1
Incentive Sensitization - Breakpoint0.30.30.8-0.40.50.5-0.6-0.60.6-0.50.5-0.50.70.50.5-0.6-0.4-0.7-0.9-0.7-0.0
Sum of active levers in priming session hrs 5-60.00.00.10.1-0.1-0.20.10.2-0.20.3-0.00.0-0.2-0.3-0.30.1-0.10.10.10.10.1
Progressive ratio0.10.20.80.3-0.4-0.40.40.5-0.40.3-0.40.4-0.7-0.3-0.30.50.40.30.80.9-0.2
Food seeking constrained by brief footshock0.30.30.70.3-0.5-0.50.50.5-0.40.2-0.70.7-0.8-0.3-0.30.50.80.40.70.90.4
Seeking ratio, punishment vs. effort0.00.00.2-0.0-0.0-0.00.0-0.00.0-0.0-0.10.10.1-0.1-0.1-0.10.20.2-0.2-0.20.4
Retroperitoneal fat weight0.21.02.70.9-0.7-0.70.80.8-0.50.7-1.51.5-0.9-0.9-0.90.81.61.21.11.00.3
Reaction time number correct0.40.81.3-1.00.90.9-0.9-0.90.8-0.90.7-0.71.00.90.9-0.9-0.9-0.6-1.1-1.0-0.6
Reaction time mean minus median4.511.114.13.8-3.2-3.23.53.5-3.53.5-3.23.2-3.3-3.5-3.53.63.23.23.53.71.1
Reaction time mean minus median AUC3.17.810.93.3-2.7-2.72.93.0-3.02.9-2.62.6-2.8-2.9-2.93.02.72.52.93.21.0
Reaction time num false alarms1.92.73.81.9-1.5-1.51.71.6-1.61.8-1.51.5-1.7-1.7-1.71.71.51.81.81.70.7
Reaction time num false alarms AUC2.64.05.92.4-1.9-1.92.12.0-2.02.2-1.81.8-2.0-2.0-2.02.11.82.12.32.30.5
Reaction time trials correct on left0.40.81.3-1.00.90.9-0.9-0.90.8-0.90.7-0.71.00.90.9-0.9-0.9-0.6-1.1-1.0-0.6
Reaction time trials on left0.30.50.9-0.80.80.8-0.7-0.70.6-0.70.5-0.50.80.70.7-0.7-0.7-0.5-1.0-0.8-0.6
Reaction time mean0.50.71.21.1-0.8-0.80.70.9-1.01.0-0.70.7-0.6-1.0-1.01.00.80.90.90.9-0.0
Reaction time mean AUC0.30.40.80.9-0.5-0.50.50.7-0.70.8-0.50.5-0.3-0.8-0.80.70.60.70.70.7-0.4
Median of all reaction times0.10.10.3-0.10.30.3-0.4-0.20.2-0.10.4-0.40.50.10.1-0.2-0.3-0.1-0.2-0.3-0.5
Reaction time omissions9.614.015.53.9-3.7-3.73.93.9-3.93.9-3.93.9-3.6-3.8-3.83.93.93.93.83.71.9
Reaction time false alarm rate2.43.35.02.2-1.7-1.71.91.9-1.81.9-1.61.6-1.9-1.8-1.81.91.71.82.22.10.6
Reaction time premature initiation rate3.95.56.62.3-2.5-2.52.52.4-2.32.6-2.22.2-2.5-2.4-2.42.32.22.32.02.12.2
Reaction time premature initiations1.83.24.11.7-1.9-1.91.91.8-1.92.0-1.71.7-1.9-1.9-1.91.81.71.91.41.51.7
Std. dev. reaction times4.68.511.23.4-2.8-2.83.03.1-3.13.0-2.82.8-2.8-3.0-3.03.12.92.83.13.11.1
Reaction time trials completed0.30.50.9-0.80.80.8-0.7-0.70.6-0.70.5-0.50.80.70.7-0.7-0.7-0.5-1.0-0.8-0.6
Reaction time trials AUC0.61.11.6-1.21.11.1-1.0-1.11.0-1.10.8-0.81.11.11.1-1.1-1.0-0.8-1.3-1.2-0.8
Run reversals in cocaine runway, females0.10.10.20.4-0.3-0.30.30.3-0.40.40.3-0.3-0.2-0.4-0.40.2-0.20.2-0.20.10.4
Run reversals in cocaine runway, males1.11.11.30.9-1.1-1.11.11.0-1.01.0-1.21.2-1.0-1.0-1.01.01.11.01.00.81.1
Latency to leave start box in cocaine runway0.10.10.20.4-0.2-0.20.20.2-0.20.40.1-0.1-0.1-0.4-0.40.10.10.30.2-0.00.4
Latency to leave start box in cocaine runway, F1.11.32.91.4-1.3-1.31.11.1-1.21.2-0.90.9-1.1-1.2-1.21.00.90.90.80.61.7
Latency to leave start box in cocaine runway, M1.61.52.1-1.21.41.4-1.2-1.31.3-1.21.4-1.41.31.21.2-1.3-1.2-0.7-0.9-1.0-1.5
Std. dev. time between licks in bursts0.60.91.60.7-1.1-1.10.91.0-1.10.9-0.70.7-1.0-1.0-1.00.90.90.90.60.61.3
Total sessions with >9 infusions0.70.91.61.1-0.9-0.90.80.9-0.80.9-1.31.3-1.0-0.8-0.81.01.20.61.10.90.4
Short access day 1 total inactive lever presses1.11.52.01.3-1.2-1.21.21.2-1.21.4-1.41.4-1.3-1.3-1.31.21.11.01.11.20.8
Short access day 10 total inactive lever presses0.10.30.90.4-0.6-0.60.60.5-0.60.6-0.50.5-0.5-0.6-0.60.50.40.50.20.21.0
Short access day 1 total infusions0.20.20.80.9-0.3-0.30.30.4-0.30.3-0.80.8-0.5-0.3-0.30.40.60.20.60.6-0.2
Short access day 10 total infusions0.60.71.10.9-0.9-0.91.00.9-0.90.8-1.01.0-0.8-0.8-0.80.90.90.80.90.70.4
Short access total infusions1.11.42.01.4-1.2-1.21.11.2-1.11.1-1.41.4-1.2-1.1-1.11.21.20.91.11.10.9
Short access day 1 locomotion0.10.10.4-0.1-0.0-0.0-0.2-0.10.3-0.3-0.10.1-0.20.30.3-0.2-0.0-0.7-0.1-0.20.5
Short access day 10 total locomotion0.20.44.10.3-0.7-0.70.40.4-0.30.5-0.40.4-0.6-0.5-0.50.20.2-0.00.1-0.32.0
Short access total locomotion0.40.53.00.6-0.9-0.90.50.6-0.50.5-0.60.6-0.8-0.5-0.50.50.50.00.30.11.7
One hour access (0.3 mA shock)0.00.00.10.3-0.0-0.00.10.1-0.1-0.00.0-0.00.10.00.00.1-0.0-0.1-0.00.0-0.3
Compulsive drug intake0.10.10.50.3-0.1-0.10.20.3-0.30.2-0.20.2-0.4-0.2-0.20.30.20.20.40.7-0.5
One hour access (shock baseline)0.10.20.4-0.30.40.4-0.5-0.40.5-0.50.4-0.40.60.50.5-0.4-0.3-0.5-0.4-0.7-0.3
Social response proportion0.20.20.60.8-0.4-0.40.60.5-0.60.6-0.20.2-0.4-0.6-0.60.50.10.50.40.5-0.2
Social responses7.19.212.93.6-3.2-3.23.33.1-3.33.3-2.62.6-3.2-3.2-3.23.12.53.02.62.82.4
Social time0.20.32.40.40.00.00.10.3-0.50.6-0.20.20.1-0.5-0.50.50.00.30.50.6-1.5
Soleus weight0.71.92.7-1.51.41.5-1.4-1.51.6-1.51.3-1.31.31.51.5-1.5-1.4-1.5-1.3-1.3-0.6
Bone: stiffness17.127.830.6-5.45.35.3-5.3-5.45.3-5.55.4-5.45.45.55.5-5.3-5.3-5.5-4.9-4.9-3.7
Tibialis anterior weight2.06.99.1-2.62.42.4-2.5-2.72.8-2.92.7-2.72.42.92.9-2.8-2.8-3.0-2.7-2.6-0.6
Time to tail flick, vehicle, before self-admin2.32.42.81.6-1.6-1.61.71.6-1.71.6-1.51.5-1.6-1.6-1.61.61.51.41.51.50.9
Time to tail flick, vehicle, after self-admin0.10.10.50.30.00.0-0.1-0.20.1-0.30.2-0.20.30.10.1-0.3-0.5-0.4-0.7-0.70.7
Time to tail flick, test, before self-admin0.50.51.30.3-0.6-0.60.70.7-0.70.7-0.90.9-0.5-0.7-0.70.71.10.90.60.70.1
Time to tail flick, test, after self-admin0.40.40.7-0.40.70.7-0.5-0.70.6-0.50.8-0.80.70.50.5-0.6-0.6-0.5-0.5-0.4-0.7
Delta time to tail flick, vehicle, before/after SA0.60.60.8-0.60.80.8-0.9-0.80.8-0.80.8-0.80.90.80.8-0.8-0.9-0.7-0.9-0.8-0.4
Delta time to tail flick, test, before/after SA0.30.30.6-0.00.60.6-0.6-0.60.7-0.60.7-0.70.40.60.6-0.6-0.8-0.8-0.3-0.3-0.3
Tibia length7.420.324.4-4.74.64.5-4.6-4.54.3-4.44.9-4.94.74.44.4-4.5-4.7-4.6-4.4-4.3-3.2
Ambulatory time before self-admin1.52.33.41.4-1.7-1.71.51.5-1.51.5-1.81.8-1.5-1.5-1.51.41.51.41.01.11.8
Ambulatory time after self-admin0.91.11.30.9-1.1-1.11.11.1-1.11.1-1.21.2-1.1-1.0-1.01.01.11.10.80.90.9
Bone: tissue strength0.50.50.7-0.80.60.6-0.8-0.70.6-0.80.8-0.80.70.70.7-0.7-0.7-0.8-0.8-0.8-0.2
Total heroin consumption1.21.43.4-1.40.80.8-1.1-1.11.1-1.21.0-1.01.11.01.0-1.2-1.3-1.3-1.9-1.70.4
Bone: trabecular number5.08.313.4-3.23.23.1-3.0-2.82.7-2.93.0-3.03.02.92.9-2.6-2.7-2.8-1.8-1.9-3.7
Bone: trabecular spacing1.92.56.71.8-1.7-1.71.61.4-1.41.6-1.71.7-1.6-1.5-1.51.31.41.60.70.72.6
Bone: trabecular thickness0.10.10.60.1-0.1-0.10.20.3-0.40.2-0.30.3-0.2-0.3-0.30.40.10.10.50.6-0.8
Bone: trabecular tissue density0.10.21.60.4-0.5-0.50.10.2-0.30.1-0.10.1-0.2-0.2-0.20.10.20.1-0.4-0.41.3
Water consumed over 24 hours0.10.10.4-0.30.40.4-0.3-0.40.5-0.30.1-0.10.20.30.3-0.3-0.2-0.3-0.00.0-0.6
Number of responses in last shaping day0.10.21.30.1-0.1-0.1-0.3-0.20.3-0.30.1-0.1-0.10.30.3-0.3-0.5-0.7-0.4-0.41.2