Hub : Genes

Mapkbp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Mapkbp1 0.21 0.11 2.5e-03 0.09 0.08 0.05 0.06 3.2e-03 6.9e-03 2.1e-02 1.4e-02
2 pVTA isoform ratio XM_006234781.5 0.03 0.02 8.8e-03 0.02 0.02 0.02 0.02 4.4e-03 7.3e-03 1.1e-02 1.1e-02
3 Brain mRNA stability Mapkbp1 0.09 0.05 1.5e-08 0.09 0.08 0.08 0.08 1.8e-08 1.3e-07 1.2e-07 6.9e-08
4 PL gene expression Mapkbp1 0.09 0.04 1.1e-12 0.09 0.11 0.11 0.11 2.2e-10 3.8e-12 2.4e-12 3.8e-12
5 NAcc isoform ratio XM_006234781.5 0.05 0.03 3.4e-09 0.05 0.05 0.05 0.05 1.6e-07 1.8e-08 2.5e-08 2.4e-08
6 NAcc isoform ratio NM_001108589.1 0.05 0.03 9.1e-10 0.05 0.06 0.05 0.05 1.6e-08 3.8e-09 1.9e-08 1.6e-08
7 BLA gene expression Mapkbp1 0.19 0.09 4.1e-10 0.08 0.12 0.09 0.13 7.7e-05 3.7e-07 1.8e-05 2.9e-07
8 NAcc gene expression Mapkbp1 0.16 0.07 1.2e-07 0.02 0.04 0.04 0.03 1.3e-03 6.3e-07 5.8e-07 1.3e-05
9 Liver gene expression Mapkbp1 0.04 0.03 3.5e-03 0 0.01 0 0 8.1e-02 3.8e-02 8.4e-02 1.4e-01
10 BLA mRNA stability Mapkbp1 0.06 0.04 8.0e-03 0.03 0.03 0.01 0.02 1.1e-02 1.2e-02 7.4e-02 2.9e-02
11 PL intron excision ratio chr3_127437355_127437545 0.04 0.02 5.9e-05 0.03 0.02 0.01 0.02 4.3e-04 9.5e-04 1.4e-02 1.8e-03
12 PL intron excision ratio chr3_127437355_127437672 0.04 0.02 6.0e-05 0.03 0.03 0.01 0.03 3.1e-04 8.6e-04 8.4e-03 7.9e-04
13 PL isoform ratio NM_001108589.1 0.02 0.02 3.6e-03 0.01 0.01 0.01 0.01 2.9e-02 4.2e-02 6.3e-02 5.1e-02
14 BLA isoform ratio XM_006234781.5 0.08 0.04 3.2e-04 0.03 0.04 0.02 0.04 1.6e-02 2.3e-03 2.4e-02 5.9e-03
15 BLA isoform ratio NM_001108589.1 0.08 0.05 1.1e-04 0.04 0.06 0.04 0.05 6.0e-03 5.5e-04 4.7e-03 1.6e-03
16 Brain isoform ratio NM_001108589.1 0.09 0.05 1.4e-10 0.11 0.11 0.1 0.1 1.0e-10 2.6e-10 2.2e-09 9.3e-10
17 Brain isoform ratio XM_006234781.5 0.1 0.05 2.1e-11 0.12 0.12 0.11 0.11 1.6e-11 4.0e-11 4.4e-10 1.8e-10
18 IC gene expression Mapkbp1 0.13 0.07 4.1e-04 0.07 0.1 0.06 0.07 7.2e-04 5.8e-05 1.3e-03 6.6e-04
19 Brain gene expression Mapkbp1 0.39 0.15 0.0e+00 0.18 0.26 0.28 0.27 3.2e-16 3.4e-24 2.6e-26 5.3e-25
20 PL isoform ratio XM_006234781.5 0.02 0.01 6.6e-03 0.01 0 0 0 4.0e-02 7.6e-02 1.3e-01 8.6e-02
21 NAcc mRNA stability Mapkbp1 0.02 0.01 8.1e-04 0.01 0.02 0.02 0.01 3.4e-03 6.1e-04 4.3e-04 4.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.01.72.61.2-1.31.21.5-1.41.41.60.2-1.41.21.2-1.21.2-1.41.41.2-1.21.11.3-1.51.6
Area under the delay curve1.92.26.50.6-0.40.61.2-0.80.71.0-2.6-0.30.62.0-2.02.0-2.42.41.9-1.9-0.40.2-1.81.3
BMI with tail4.615.920.54.3-4.24.14.5-4.44.44.41.2-4.14.14.3-4.34.3-3.93.94.2-4.23.53.6-4.11.9
BMI without tail6.720.428.54.9-4.94.75.2-4.95.05.33.1-4.84.24.5-4.54.5-4.34.34.6-4.64.14.5-4.52.5
Body weight5.825.432.75.5-5.65.35.7-5.65.65.62.6-5.35.25.2-5.25.2-4.64.55.1-5.14.64.7-5.13.4
Weight adjusted by age0.91.42.51.2-1.11.51.2-1.31.21.00.7-1.01.31.6-1.61.5-0.90.91.5-1.50.80.7-1.00.4
Bone surface1.12.03.51.5-1.91.41.5-1.51.61.61.4-1.81.80.9-0.90.9-0.80.80.9-0.91.81.7-1.11.8
Bone volume1.12.03.31.6-1.61.51.5-1.61.61.60.6-1.81.71.1-1.11.1-1.01.01.0-1.01.71.7-1.11.7
Breakpoint value in progressive ratio session0.20.20.6-0.60.8-0.5-0.60.4-0.3-0.2-0.6-0.0-0.3-0.70.7-0.70.4-0.4-0.60.60.1-0.00.40.6
Number of licking bursts0.10.20.6-0.70.8-0.7-0.50.5-0.4-0.1-0.50.0-0.1-0.60.6-0.60.1-0.1-0.60.60.00.10.50.4
Context. condit. distance diff. score2.22.76.12.0-1.91.91.8-1.71.82.02.5-2.01.11.3-1.31.3-1.01.01.2-1.22.02.2-0.71.1
Locomotion velocity, session 13.63.97.3-2.32.2-2.4-2.02.3-2.4-2.3-1.52.6-2.4-1.41.4-1.40.9-0.9-1.51.5-2.7-2.71.3-1.3
Locomotion distance, session 11.41.84.1-1.61.5-1.6-1.41.6-1.7-1.5-0.71.9-2.0-0.90.9-0.90.5-0.5-0.90.9-2.0-1.71.0-0.3
Locomotion velocity, session 21.01.14.00.1-0.20.10.8-0.30.30.6-0.90.1-0.41.4-1.41.4-2.02.01.4-1.4-0.7-0.4-1.11.0
Locomotion distance, session 20.40.51.9-0.90.7-1.0-0.70.9-0.9-0.60.21.0-1.4-0.50.5-0.50.0-0.0-0.50.5-1.1-0.60.70.6
Locomotion velocity, session 30.50.54.1-0.50.5-0.6-0.10.4-0.4-0.4-2.00.5-0.50.5-0.50.5-0.90.90.4-0.4-0.8-0.90.00.7
Locomotion distance, session 30.20.21.5-0.20.4-0.2-0.30.5-0.3-0.1-0.10.0-0.8-0.10.1-0.1-0.20.2-0.10.1-0.1-0.11.21.1
Stereotopy head waving bouts, day 32.93.46.21.9-1.92.02.1-1.91.71.6-0.2-1.31.52.3-2.32.3-1.91.92.5-2.50.90.7-2.01.0
Stereotopy head waving duration, day 33.44.17.51.6-1.61.62.2-1.91.71.7-1.2-1.11.62.7-2.72.7-2.62.62.7-2.70.50.4-2.70.7
Locomotion velocity, session 70.30.31.10.6-0.60.50.5-0.20.20.41.0-0.2-0.70.6-0.60.6-0.60.60.5-0.50.10.30.61.0
Locomotion distance, session 70.30.43.80.3-0.30.30.10.00.00.22.0-0.2-0.6-0.30.3-0.30.4-0.4-0.40.40.40.80.90.9
Stereotopy head waving bouts, day 70.10.11.2-0.30.2-0.2-0.30.2-0.3-0.5-1.10.30.0-0.20.2-0.20.3-0.3-0.10.1-0.3-0.60.10.1
Stereotopy head waving duration, day 70.10.11.30.0-0.0-0.0-0.1-0.0-0.0-0.4-1.10.00.4-0.00.0-0.00.3-0.3-0.10.10.0-0.4-0.1-0.0
Locomotion velocity, session 82.12.65.61.5-1.11.31.7-1.41.31.5-0.1-0.90.42.3-2.32.3-2.42.42.1-2.10.40.7-1.50.7
Locomotion distance, session 80.81.14.81.2-1.31.01.2-0.90.91.32.2-0.9-0.10.8-0.80.8-0.90.90.7-0.70.91.5-0.21.5
Degree of sensitization distance0.40.51.70.2-0.20.2-0.2-0.10.1-0.21.3-0.10.4-0.80.8-0.81.3-1.3-0.80.80.50.50.1-0.8
Degree of sensitization stereotypy0.40.41.4-0.30.2-0.3-0.70.4-0.4-0.7-0.10.2-0.1-0.80.8-0.81.2-1.2-0.90.90.1-0.30.9-0.2
Conditioned locomotion1.82.13.41.5-1.51.51.7-1.61.61.81.0-1.51.31.4-1.41.4-1.41.41.4-1.41.31.5-1.50.2
Cocaine response after cond. corrected1.21.43.5-1.81.8-1.8-1.31.5-1.3-1.0-1.91.0-1.0-1.01.0-1.00.1-0.0-1.01.0-1.2-1.10.9-0.1
Cocaine response after cond. not corrected1.72.05.2-2.12.1-2.1-1.41.8-1.6-1.2-2.31.4-1.4-1.11.1-1.1-0.00.0-1.11.1-1.7-1.40.90.0
Cocaine response before conditioning0.20.21.0-0.20.1-0.4-0.20.4-0.6-0.5-0.30.9-0.90.1-0.10.1-0.00.00.1-0.1-1.0-0.70.00.2
Saline control response2.12.75.32.3-2.12.31.8-2.01.91.51.1-1.61.91.7-1.71.7-0.80.71.7-1.71.61.2-1.6-0.0
Bone: connectivity density0.50.92.20.9-1.40.91.1-1.01.00.90.6-0.91.20.7-0.70.7-0.50.50.6-0.60.80.8-1.21.5
Bone: cortical apparent density1.21.74.3-0.80.9-0.7-1.40.9-0.8-1.00.00.2-0.1-1.91.9-1.92.1-2.1-1.81.80.30.01.6-0.5
Bone: cortical area1.82.83.81.9-1.71.81.8-1.91.91.80.4-1.81.91.8-1.81.8-1.61.61.8-1.81.51.5-1.70.9
Bone: cortical porosity1.01.13.2-1.41.5-1.3-0.51.0-1.1-0.5-1.71.3-1.70.2-0.20.2-1.11.10.2-0.2-1.8-1.3-0.10.2
Bone: cortical porosity0.60.72.0-0.50.6-0.50.20.3-0.30.0-1.20.7-1.00.8-0.80.8-1.41.40.8-0.8-1.1-0.8-0.50.2
Bone: cortical thickness1.32.23.21.5-1.31.41.6-1.51.51.5-0.1-1.21.31.8-1.81.8-1.81.71.8-1.80.90.9-1.61.0
Bone: cortical thickness0.20.21.7-0.40.6-0.3-0.1-0.00.20.3-1.3-0.50.7-0.20.2-0.2-0.40.4-0.20.20.40.2-0.30.9
Bone: cortical tissue density1.21.74.0-0.90.9-0.8-1.40.9-0.8-1.0-0.20.3-0.1-1.91.9-1.92.0-2.0-1.81.80.2-0.11.6-0.5
Condit. Reinf. active minus inactive responses0.91.14.50.1-0.20.2-0.80.3-0.4-0.91.40.2-0.0-1.21.2-1.22.1-2.1-1.21.20.40.01.3-0.4
Condit. Reinf. active-inactive response ratio0.30.41.01.0-0.81.00.4-0.70.60.30.7-0.70.80.2-0.20.20.5-0.50.3-0.30.90.70.10.1
Condit. Reinf. active responses2.32.810.0-0.30.0-0.3-1.50.9-0.9-1.62.10.7-0.5-2.12.1-2.13.2-3.2-2.12.10.1-0.32.1-0.6
Condit. Reinf. inactive responses2.32.87.3-0.90.5-0.9-1.61.3-1.3-1.61.81.0-1.1-2.22.2-2.22.7-2.7-2.22.2-0.3-0.62.1-0.5
Incentive salience index mean1.82.27.4-0.60.3-0.5-1.51.0-1.1-1.61.21.0-0.7-1.91.9-1.92.7-2.7-1.81.8-0.3-0.61.7-0.5
Condit. Reinf. lever presses1.21.75.4-0.70.2-0.6-1.41.0-1.1-1.51.01.1-0.8-1.61.6-1.62.3-2.3-1.51.5-0.6-0.71.30.0
Condit. Reinf. active minus inactive responses1.11.54.81.4-1.71.61.0-1.41.41.12.2-1.51.80.1-0.10.10.6-0.60.1-0.11.91.6-0.60.1
Condit. Reinf. active-inactive response ratio0.91.03.21.1-1.11.30.7-1.11.11.01.8-1.41.50.0-0.00.00.5-0.50.1-0.11.71.5-0.4-0.3
Condit. Reinf. active responses1.52.15.01.8-2.12.01.2-1.71.71.32.1-1.92.10.4-0.40.40.6-0.60.4-0.42.21.9-0.80.5
Condit. Reinf. inactive responses0.70.92.31.3-1.51.30.9-1.21.10.60.3-1.11.50.5-0.50.50.4-0.40.5-0.51.31.0-0.70.6
Condit. Reinf. lever presses0.91.35.01.4-1.71.61.0-1.41.30.80.5-1.32.20.7-0.70.70.3-0.30.7-0.71.40.7-1.1-0.2
Condit. Reinf. lever reinforcers received1.21.74.11.6-2.01.81.0-1.51.51.12.0-1.62.00.2-0.20.20.8-0.80.2-0.22.01.6-0.70.4
Conditioned reinforcement - actives0.20.41.1-1.00.8-0.6-0.60.7-0.7-0.6-0.60.8-0.3-0.50.5-0.50.2-0.2-0.30.3-0.8-0.80.2-1.0
Conditioned reinforcement - inactives0.10.11.1-0.0-0.10.10.1-0.00.10.31.1-0.20.10.0-0.00.0-0.20.20.0-0.00.20.10.2-0.8
Conditioned locomotion0.40.63.1-0.60.4-0.4-0.30.5-0.6-0.7-0.81.1-0.60.3-0.30.3-0.20.20.3-0.3-1.3-1.6-0.2-1.8
Patch foraging indifference point 0 sec1.52.75.11.9-1.71.81.7-1.81.50.9-1.4-1.02.02.2-2.22.3-1.31.32.2-2.20.70.0-1.9-0.1
Patch foraging indifference point AUC2.13.04.1-1.72.0-1.5-2.01.9-1.9-1.9-1.01.8-1.8-2.02.0-1.91.8-1.8-1.61.6-1.4-1.61.9-0.7
Delay disc. indifference point, 0s delay0.30.43.3-0.10.2-0.1-0.10.1-0.3-0.5-1.80.6-0.10.5-0.50.6-0.40.40.6-0.6-0.8-0.9-0.5-0.3
Delay disc. indifference point, 16s delay0.91.08.8-0.40.6-0.40.10.3-0.4-0.1-3.00.6-0.20.9-0.90.8-1.41.40.8-0.8-1.1-0.8-0.50.8
Delay disc. indifference point, 2s delay0.70.81.51.1-0.81.10.8-1.01.01.00.5-1.00.60.8-0.80.9-0.50.50.8-0.81.01.2-0.41.2
Delay disc. indifference point, 24s delay1.11.22.9-1.31.2-1.3-1.21.3-1.4-1.3-1.61.6-1.1-0.70.7-0.80.4-0.3-0.60.6-1.7-1.40.6-0.1
Delay disc. indifference point, 4s delay1.01.03.00.3-0.20.40.8-0.50.40.8-1.4-0.10.11.4-1.41.4-1.71.71.4-1.4-0.40.2-1.20.8
Delay disc. indifference point, 8s delay3.74.39.21.2-1.01.21.9-1.51.41.7-2.8-0.91.52.7-2.72.7-3.03.02.7-2.70.10.6-2.51.7
Indifference point function ln k2.95.17.22.2-2.32.22.7-2.32.42.71.4-2.32.12.4-2.42.4-2.62.62.4-2.41.92.0-2.20.9
Indifference point function log k2.95.17.22.2-2.32.22.7-2.32.42.71.4-2.32.12.4-2.42.4-2.62.62.4-2.41.92.0-2.20.9
Patch foraging total patch changes 0 sec1.32.44.21.7-1.61.71.5-1.71.50.8-1.4-1.01.92.0-2.02.1-1.11.12.0-2.00.80.0-1.70.2
Patch foraging total patch changes 12 sec0.10.20.90.30.10.6-0.3-0.0-0.1-0.4-0.70.2-0.0-0.20.2-0.20.9-0.90.2-0.20.0-0.40.4-0.3
Patch foraging total patch changes 18 sec0.40.61.5-0.40.7-0.3-1.00.7-0.8-1.0-0.40.8-0.5-0.90.9-0.91.2-1.2-0.70.7-0.5-0.81.0-0.3
Patch foraging total patch changes 24 sec0.81.43.51.0-1.21.21.3-1.31.11.1-0.5-0.81.61.2-1.21.2-1.11.11.5-1.50.60.3-1.9-0.1
Patch foraging total patch changes 6 sec0.10.20.6-0.00.40.1-0.50.2-0.3-0.7-0.60.4-0.2-0.20.2-0.20.8-0.8-0.10.1-0.3-0.80.7-0.4
Patch foraging time to switch 0 sec0.30.62.2-0.50.2-0.3-0.80.4-0.5-0.90.10.6-0.2-0.90.9-0.91.5-1.5-0.90.9-0.2-0.50.6-0.4
Patch foraging water rate 0 sec0.61.22.61.4-1.31.31.2-1.21.31.30.7-1.61.30.8-0.80.8-0.70.70.8-0.81.61.4-0.50.9
Patch foraging water rate 12 sec0.10.31.40.2-0.10.00.3-0.20.50.81.0-1.00.4-0.10.1-0.1-0.40.4-0.20.21.01.20.20.4
Patch foraging water rate 18 sec0.50.72.40.4-0.20.20.8-0.60.71.1-0.3-0.90.51.0-1.01.0-1.51.50.7-0.70.60.8-0.70.8
Patch foraging water rate 24 sec0.50.83.11.0-0.80.80.6-0.81.00.91.3-1.61.30.1-0.10.10.0-0.00.0-0.01.81.50.40.1
Patch foraging water rate 6 sec0.60.82.1-0.70.7-0.8-0.80.7-0.5-0.40.7-0.2-0.2-1.31.3-1.31.0-1.0-1.41.40.50.41.3-0.7
Seeking ratio, delayed vs. immediate footshock0.70.84.40.8-0.61.10.6-0.91.01.12.1-1.30.50.1-0.1-0.00.3-0.30.2-0.21.51.50.1-0.3
Distance traveled before self-admin0.60.81.40.7-1.00.91.1-0.91.01.20.4-0.90.70.9-0.90.7-1.01.00.9-0.90.70.8-1.20.2
Distance traveled after self-admin0.20.32.70.2-0.40.30.2-0.40.50.40.4-0.70.3-0.20.2-0.10.2-0.2-0.30.30.90.8-0.31.6
Extensor digitorum longus weight0.31.43.81.0-1.11.01.2-1.01.01.1-0.2-0.90.61.4-1.41.4-1.51.51.4-1.40.60.5-0.92.0
Bone: elastic displacement0.20.22.3-0.30.5-0.2-0.30.2-0.3-0.5-1.50.4-0.40.2-0.20.2-0.10.10.1-0.1-0.5-0.70.1-0.3
Bone: elastic work0.50.61.11.0-0.61.00.7-0.90.80.5-0.9-0.81.00.9-0.90.9-0.40.40.9-0.90.70.3-0.6-0.1
Bone: endosteal estimation0.10.31.40.5-0.50.30.4-0.40.50.71.2-0.80.3-0.10.1-0.1-0.20.2-0.10.10.80.9-0.10.7
Bone: endosteal perimeter0.10.10.80.4-0.20.20.2-0.20.30.30.9-0.40.3-0.10.1-0.10.1-0.1-0.10.10.50.5-0.0-0.4
Epididymis fat weight0.41.53.60.9-0.70.81.3-0.90.91.1-0.6-0.60.21.6-1.61.6-1.91.91.6-1.60.10.4-1.31.6
Delta time in closed arm before/after self-admin0.30.33.60.3-0.10.30.0-0.00.10.21.9-0.2-0.1-0.10.1-0.30.3-0.3-0.20.20.40.60.7-0.2
Delta time in open arm before/after self-admin1.41.44.21.2-1.11.31.1-1.21.41.71.4-1.71.20.5-0.50.6-0.60.60.6-0.61.82.0-0.50.6
Diff in mean of infusions in LGA sessions0.20.21.1-0.0-0.20.2-0.40.2-0.2-0.30.90.2-0.1-0.60.6-0.51.1-1.1-0.40.40.1-0.20.6-0.2
Delay discount exponential model param1.61.85.1-0.40.2-0.5-1.00.6-0.5-1.02.30.2-0.4-1.81.8-1.72.2-2.2-1.71.70.5-0.21.6-1.3
Extinction: sum of active levers before priming1.01.12.1-1.41.4-1.3-1.21.2-1.2-1.2-1.41.3-1.3-0.70.7-0.70.4-0.4-0.70.7-1.3-1.30.8-0.2
Active lever presses in extinction session 60.50.51.8-0.81.2-0.7-0.60.8-0.8-0.6-1.11.0-1.3-0.10.1-0.1-0.20.2-0.00.0-1.1-0.90.20.6
Bone: final force1.01.53.51.8-1.51.61.2-1.31.41.21.9-1.51.20.8-0.80.8-0.30.30.8-0.81.71.5-0.21.2
Bone: final moment0.81.22.81.7-1.31.51.0-1.21.31.11.6-1.41.00.8-0.80.8-0.20.20.7-0.71.61.3-0.21.0
Food consumed during 24 hour testing period0.10.10.2-0.40.3-0.4-0.10.2-0.10.10.1-0.0-0.2-0.30.3-0.3-0.20.2-0.40.4-0.00.20.10.4
Glucose1.32.05.31.6-1.31.51.4-1.31.41.60.9-1.60.41.4-1.41.4-1.31.31.3-1.31.51.9-0.22.3
Heart weight4.87.411.23.0-3.33.03.2-2.92.93.22.6-2.72.72.7-2.72.7-2.52.52.7-2.72.42.6-2.60.8
Delay discount hyperbolic model param1.51.74.3-0.60.4-0.7-1.10.8-0.7-1.01.90.4-0.5-1.81.8-1.72.1-2.1-1.71.70.2-0.41.5-1.2
Intermittent access intake day 1-15 change0.40.73.60.4-0.70.30.8-0.50.71.01.5-1.11.50.2-0.20.2-0.80.80.1-0.11.00.7-0.3-1.9
Intermittent access intake escalation0.40.82.80.6-0.70.50.9-0.81.01.21.0-1.41.70.4-0.40.4-0.90.90.3-0.31.30.9-0.6-1.2
Intermittent access intake escalation 20.30.32.1-0.60.4-0.70.10.4-0.10.50.4-0.30.5-0.30.3-0.3-0.90.9-0.30.30.10.40.1-1.5
Intermitt. access day 1 inactive lever presses0.62.13.61.8-1.91.51.7-1.71.61.31.7-1.21.11.6-1.61.6-1.11.11.3-1.31.01.3-1.91.0
Intermitt. access day 15 inactive lever presses0.51.04.21.2-1.11.31.0-1.01.11.12.0-1.10.90.8-0.80.8-0.50.50.8-0.81.11.2-0.5-0.5
Intermitt. access escalation Index0.50.72.21.1-1.11.00.5-0.91.00.51.4-1.11.20.1-0.10.10.7-0.7-0.00.01.50.9-0.00.5
Intermittent access day 1 total infusions0.30.42.4-0.60.7-0.3-0.60.6-0.7-0.7-0.60.9-0.5-0.10.1-0.10.3-0.30.1-0.1-0.9-1.10.4-1.5
Intermittent access day 15 total infusions0.40.53.60.5-0.50.60.6-0.50.60.71.0-0.81.20.4-0.40.4-0.40.40.5-0.50.70.3-0.2-1.9
Intermittent access terminal intake (last 3 days)0.30.43.30.0-0.30.30.5-0.30.40.70.9-0.71.00.3-0.30.3-0.60.60.3-0.30.60.5-0.0-1.8
Intermittent access total infusions0.20.23.10.0-0.10.30.2-0.20.20.30.3-0.20.60.3-0.30.3-0.30.30.4-0.40.10.0-0.1-1.7
Intermittent access day 1 locomotion0.60.81.90.4-0.50.60.7-0.50.30.3-0.80.20.21.3-1.31.3-1.11.11.4-1.4-0.5-0.6-0.9-1.1
Intermittent access day 15 total locomotion0.40.71.50.6-0.70.81.0-0.80.91.21.2-0.90.60.7-0.70.7-1.01.00.8-0.80.80.9-0.7-0.5
Intermittent access total locomotion0.20.32.1-0.1-0.10.20.4-0.20.10.4-0.00.00.20.6-0.60.6-0.80.80.7-0.7-0.3-0.2-0.6-1.5
Intermittent access standard deviation0.20.31.90.2-0.40.20.5-0.30.40.61.4-0.60.90.3-0.30.3-0.60.60.1-0.10.60.40.1-1.1
Left kidney weight3.114.520.44.0-3.53.94.3-3.83.84.22.2-3.12.04.5-4.54.5-4.34.34.4-4.42.43.2-3.63.4
Right kidney weight4.520.328.34.7-4.34.55.2-4.64.54.92.1-3.62.95.3-5.35.3-5.15.15.3-5.32.63.5-4.83.5
Cocaine induced anxiety0.91.32.41.2-1.41.21.3-1.00.80.91.5-0.20.21.5-1.51.5-1.21.21.6-1.6-0.10.6-1.1-0.3
Post-drug Anxiety1.92.07.21.7-1.91.71.6-1.41.31.42.7-0.80.21.5-1.51.5-1.11.11.5-1.50.71.4-1.10.5
Baseline Anxiety0.20.21.20.4-0.40.30.1-0.30.40.30.6-0.60.1-0.20.2-0.20.3-0.3-0.30.30.80.80.31.1
Tail length2.59.814.93.4-3.63.43.6-3.43.53.93.6-3.42.82.6-2.62.6-2.62.62.8-2.83.13.5-2.92.6
Length with tail1.77.610.73.1-3.33.13.1-3.13.13.02.5-2.92.62.5-2.52.5-2.12.12.6-2.62.72.7-2.53.0
Length without tail0.72.47.01.5-1.61.51.7-1.61.61.50.3-1.61.41.6-1.61.6-1.41.41.5-1.51.31.1-1.42.6
Times rat made contact with spout0.30.40.80.6-0.40.60.6-0.60.50.4-0.3-0.30.40.9-0.90.9-0.70.70.8-0.80.2-0.1-0.60.3
Lifetime Intake0.20.23.1-0.40.3-0.1-0.10.1-0.1-0.0-0.60.10.40.2-0.20.2-0.30.30.3-0.3-0.3-0.5-0.1-1.8
Liver weight, left4.57.513.93.0-3.32.83.1-3.23.33.11.6-3.23.72.4-2.42.4-1.91.92.2-2.23.03.0-3.20.9
Liver weight, right2.54.35.82.1-2.22.12.3-2.32.22.0-0.1-2.02.42.4-2.42.4-2.12.02.4-2.41.61.4-2.30.7
Locomotor activity0.20.30.8-0.80.7-0.6-0.50.6-0.7-0.6-0.80.8-0.7-0.20.2-0.20.2-0.2-0.10.1-0.9-0.9-0.0-0.9
Locomotor testing distance0.50.82.0-1.11.0-0.8-0.91.0-1.1-1.0-0.91.2-1.2-0.50.5-0.50.5-0.5-0.40.4-1.2-1.40.7-1.2
Locomotor testing rearing0.91.83.1-1.51.2-1.1-1.51.5-1.5-1.40.31.4-1.8-1.41.4-1.41.6-1.6-1.41.4-1.1-1.31.70.1
Locomotion in novel chamber0.30.30.90.5-0.20.70.5-0.60.50.3-0.0-0.40.60.9-0.90.9-0.40.40.8-0.80.40.0-0.3-0.9
Locomotion in novel chamber post-restriction1.52.45.21.4-1.51.31.7-1.81.92.00.8-2.12.01.0-1.01.0-1.11.11.0-1.02.02.3-1.81.6
Fecal boli incidents, locomotor time 10.91.33.1-1.41.3-1.3-1.11.3-1.3-1.1-1.81.3-0.7-0.80.8-0.80.2-0.2-0.70.7-1.5-1.50.6-1.5
Change in fecal boli incidents, locomotor task2.82.83.91.9-1.81.91.8-1.81.82.01.5-1.81.31.5-1.51.5-1.31.31.6-1.61.72.0-1.31.8
Time >=10cm from walls, locomotor time 10.10.10.3-0.10.2-0.3-0.30.1-0.0-0.10.1-0.20.1-0.40.4-0.40.4-0.4-0.60.60.40.40.40.1
Bouts of movement, locomotor time 13.94.46.7-2.52.5-2.6-2.32.4-2.4-2.3-1.72.3-1.8-1.91.9-1.91.4-1.4-2.12.1-2.2-2.31.6-1.9
Total resting periods, locomotor time 13.94.45.8-2.32.3-2.4-2.42.3-2.4-2.3-1.32.2-1.8-2.12.1-2.01.7-1.7-2.22.2-2.0-2.11.8-1.7
Rest time, locomotor task time 10.10.10.30.1-0.10.0-0.20.1-0.1-0.20.1-0.0-0.1-0.40.4-0.40.6-0.6-0.30.30.10.20.30.2
Distance moved, locomotor task time 10.10.20.5-0.40.4-0.3-0.50.3-0.4-0.6-0.60.4-0.0-0.30.3-0.40.6-0.6-0.30.3-0.2-0.70.4-0.5
Vertical activity count, locomotor time 10.10.20.90.2-0.10.30.3-0.60.60.30.5-0.81.00.1-0.10.00.1-0.1-0.10.10.90.4-0.4-0.6
Time >=10cm from walls, locomotor time 27.310.715.43.7-3.53.63.7-3.93.83.52.2-3.53.63.2-3.23.2-2.42.43.2-3.23.33.2-3.52.2
Bouts of movement, locomotor time 20.20.32.10.5-0.70.20.4-0.70.70.30.1-1.01.4-0.10.1-0.00.2-0.2-0.10.11.10.4-0.80.1
Total resting periods, locomotor time 20.20.31.90.4-0.50.10.2-0.60.60.20.1-0.91.4-0.20.2-0.20.4-0.4-0.30.31.00.4-0.7-0.2
Rest time, locomotor task time 24.15.27.7-2.42.5-2.3-2.72.7-2.7-2.4-1.02.5-2.8-2.32.3-2.42.0-2.0-2.32.3-2.2-1.72.6-1.0
Distance moved, locomotor task time 21.61.92.81.7-1.51.61.6-1.71.61.30.3-1.31.41.5-1.51.4-1.01.01.5-1.51.21.1-1.41.2
Vertical activity count, locomotor time 23.24.47.92.5-2.32.22.3-2.72.72.11.4-2.72.81.7-1.71.7-1.11.11.6-1.62.72.3-1.91.2
Light reinforcement 10.61.54.52.0-1.52.10.9-1.61.40.50.6-1.01.61.1-1.11.10.7-0.71.1-1.11.30.6-0.8-0.9
Light reinforcement 20.71.12.7-0.71.0-0.5-1.20.9-0.9-1.1-0.20.9-0.8-1.11.1-1.11.6-1.6-1.01.0-0.5-0.71.1-1.6
Bone: marrow area0.10.31.50.6-0.60.40.5-0.50.60.71.2-0.80.40.1-0.10.1-0.30.30.1-0.10.90.9-0.20.7
Bone: maximum diameter1.01.83.31.7-1.61.61.5-1.61.61.51.2-1.71.81.1-1.11.1-0.80.81.1-1.11.71.5-1.20.3
Bone: maximum force1.83.35.72.4-2.22.22.0-2.12.01.81.7-1.91.61.7-1.71.7-1.21.21.7-1.71.81.7-1.41.7
Bone: maximum moment1.52.64.72.2-1.92.01.8-1.81.81.61.4-1.71.41.6-1.61.6-1.11.11.5-1.51.61.5-1.21.4
Mean time between licks in bursts0.51.12.5-1.41.3-1.5-1.01.3-1.3-1.0-0.81.4-1.4-0.70.7-0.7-0.00.0-0.70.7-1.6-1.50.6-0.6
Mean num. licks in bursts0.40.61.31.1-1.11.10.9-0.90.80.50.6-0.40.51.0-1.01.0-0.40.41.0-1.00.40.1-0.8-0.1
Cd content in liver0.40.41.20.7-0.90.50.7-0.70.70.50.3-0.80.90.5-0.50.5-0.40.40.4-0.40.70.6-0.51.1
Co content in liver0.40.52.6-0.40.4-0.50.20.1-0.10.1-1.60.2-0.20.6-0.60.6-1.21.20.6-0.6-0.6-0.7-0.50.7
Cu content in liver0.40.51.1-0.60.7-0.7-0.70.7-0.6-0.40.70.3-0.7-0.90.9-0.90.5-0.5-0.90.9-0.2-0.11.10.1
Fe content in liver2.42.98.3-0.70.3-0.9-1.61.1-1.1-1.61.30.6-0.3-2.42.4-2.42.9-2.9-2.52.50.1-0.12.1-0.1
K content in liver0.40.40.90.2-0.40.20.6-0.50.61.00.4-0.70.80.3-0.30.3-0.90.90.3-0.30.50.6-0.80.8
Mg content in liver0.80.82.10.6-0.70.61.0-0.91.01.40.5-1.41.30.6-0.60.6-1.21.20.6-0.61.21.0-0.70.7
Mn content in liver1.71.92.81.4-1.41.61.6-1.51.41.40.7-1.21.21.6-1.61.6-1.31.31.7-1.71.00.9-1.4-0.8
Na content in liver0.50.51.1-0.80.4-0.9-0.70.7-0.6-0.50.70.5-0.4-1.01.0-1.00.7-0.7-1.11.1-0.4-0.30.3-0.1
Rb content in liver3.84.46.71.9-2.01.92.4-2.02.02.31.0-1.91.32.4-2.42.4-2.62.62.4-2.41.41.3-1.82.3
Se content in liver0.10.10.60.20.10.20.1-0.10.20.10.2-0.3-0.20.1-0.10.1-0.00.00.1-0.10.30.30.40.8
Sr content in liver0.20.20.6-0.50.5-0.6-0.30.3-0.4-0.4-0.60.6-0.20.1-0.10.1-0.20.2-0.10.1-0.7-0.6-0.2-0.8
Zn content in liver0.91.02.6-0.70.5-0.7-0.80.6-0.4-0.21.2-0.10.0-1.61.6-1.61.1-1.1-1.61.60.40.50.9-0.2
Bone: minimum diameter1.52.75.01.4-1.21.21.7-1.51.41.5-0.7-1.01.12.1-2.12.1-2.22.22.1-2.10.50.6-2.11.5
Time in familiar zone, hab. session 11.31.32.3-1.41.3-1.5-1.21.2-1.2-1.0-1.00.9-0.6-1.41.4-1.40.7-0.7-1.31.3-0.9-0.80.6-1.0
Time in novel zone, hab. session 11.81.83.61.8-1.51.91.5-1.61.51.21.2-1.31.01.6-1.61.6-0.70.71.5-1.51.31.0-0.60.5
Total zone transitions, hab. session 10.30.51.5-1.20.6-1.0-0.60.8-0.8-0.5-0.70.9-0.6-0.60.6-0.60.1-0.1-0.50.5-1.0-0.7-0.20.3
Total locomotion distance, hab. session 10.30.41.3-1.10.7-0.9-0.50.7-0.8-0.5-0.81.0-0.8-0.30.3-0.3-0.00.0-0.30.3-1.1-0.8-0.20.1
Locomotion velocity, hab. session 10.50.72.0-1.40.8-1.1-0.80.9-1.0-0.9-1.01.3-1.0-0.50.5-0.50.2-0.2-0.50.5-1.4-1.0-0.10.2
Time in familiar zone, hab. session 20.10.10.80.0-0.2-0.00.1-0.20.20.0-0.3-0.40.9-0.20.2-0.20.2-0.2-0.20.20.50.1-0.3-0.5
Time in novel zone, hab. session 20.40.41.00.7-0.30.70.6-0.50.40.50.3-0.2-0.41.0-1.01.0-0.70.70.9-0.90.10.3-0.20.6
Total zone transitions, hab. session 20.20.30.8-0.90.4-0.8-0.20.5-0.5-0.1-0.40.7-0.7-0.20.2-0.2-0.50.5-0.20.2-0.9-0.4-0.30.5
Total locomotion distance, hab. session 20.00.00.1-0.1-0.1-0.00.1-0.0-0.00.20.30.2-0.20.1-0.10.1-0.30.30.0-0.0-0.20.2-0.30.1
Locomotion velocity, hab. session 20.00.00.2-0.30.0-0.2-0.10.1-0.2-0.10.10.3-0.3-0.10.1-0.1-0.10.1-0.10.1-0.4-0.0-0.3-0.0
Novel to familiar place preference ratio1.41.62.81.7-1.51.71.3-1.51.41.21.0-1.21.41.2-1.21.2-0.50.51.3-1.31.21.1-1.2-0.9
Novelty place preference1.31.42.51.6-1.41.61.3-1.41.41.10.9-1.11.31.2-1.21.2-0.60.61.3-1.31.11.0-1.1-0.9
Time in novel zone, NPP test1.31.32.51.6-1.41.61.2-1.41.31.10.9-1.21.21.1-1.11.1-0.50.51.2-1.21.21.1-1.0-0.9
Total zone transitions, NPP test0.81.23.1-1.71.3-1.6-0.91.4-1.3-0.7-0.61.4-1.7-0.70.7-0.7-0.40.4-0.70.7-1.6-1.00.50.9
Total locomotion distance, NPP test0.40.52.2-0.80.7-0.7-0.10.7-0.7-0.1-0.31.0-1.50.2-0.20.2-1.11.10.2-0.2-1.4-0.6-0.10.7
Locomotion velocity, NPP test0.50.72.6-1.00.8-0.9-0.20.8-0.8-0.2-0.51.2-1.60.2-0.20.2-1.11.10.2-0.2-1.6-0.8-0.10.7
Intraocular pressure1.62.35.4-1.51.7-1.6-1.61.5-1.5-2.0-2.01.6-0.9-1.01.0-1.01.1-1.1-1.11.1-1.4-2.11.2-2.3
Delta distance traveled before/after self-admin0.30.30.7-0.30.3-0.6-0.60.3-0.4-0.7-0.40.3-0.1-0.60.6-0.50.8-0.8-0.90.9-0.1-0.10.50.3
Delta ambulatory time before/after self-admin0.50.61.8-0.40.4-0.6-0.90.6-0.6-1.0-0.10.6-0.5-0.90.9-0.81.3-1.3-1.01.0-0.3-0.30.80.1
Parametrial fat weight0.10.21.20.5-0.80.50.4-0.30.20.11.10.20.10.4-0.40.4-0.00.00.5-0.5-0.2-0.1-0.4-0.2
Pavlov. Cond. lever latency0.20.20.80.6-0.40.40.5-0.50.60.50.1-0.90.90.2-0.20.2-0.30.30.2-0.20.90.5-0.0-0.4
Pavlov. Cond. magazine entry latency0.30.41.81.1-1.01.20.3-0.60.50.11.3-0.20.20.2-0.20.20.9-0.90.2-0.20.50.80.0-0.3
Pavlov. Cond. change in total contacts0.30.33.70.5-0.40.50.1-0.20.20.31.9-0.2-0.6-0.20.2-0.20.4-0.4-0.20.20.30.90.40.0
Pavlov. Cond. index score0.20.20.8-0.10.20.0-0.50.3-0.4-0.60.20.6-0.5-0.40.4-0.40.9-0.9-0.30.3-0.5-0.10.3-0.4
Pavlov. Cond. latency score0.10.10.4-0.10.00.1-0.30.1-0.3-0.50.10.6-0.3-0.10.1-0.10.6-0.6-0.10.1-0.5-0.2-0.1-0.3
Pavlov. Cond. lever contacts0.20.30.7-0.50.4-0.3-0.60.5-0.6-0.60.20.9-0.8-0.40.4-0.40.6-0.6-0.30.3-0.8-0.40.20.2
Pavlov. Cond. magazine entry number0.30.41.5-1.10.9-1.2-0.40.7-0.6-0.3-1.00.3-0.2-0.40.4-0.4-0.50.5-0.50.5-0.5-0.80.10.2
Pavlov. Cond. intertrial magazine entries0.40.51.1-0.4-0.0-0.4-0.40.4-0.2-0.20.1-0.40.8-1.11.1-1.10.8-0.8-1.01.00.70.00.80.7
Pavlov. Cond. lever-magazine prob. diff.0.30.30.7-0.30.4-0.2-0.70.5-0.6-0.70.10.8-0.9-0.50.5-0.50.8-0.8-0.40.4-0.7-0.20.5-0.5
Pavlov. Cond. response bias0.30.41.40.10.00.3-0.50.2-0.3-0.41.10.4-0.8-0.60.6-0.61.2-1.2-0.50.5-0.10.30.8-0.2
Pavlov. Cond. lever latency2.53.36.9-2.52.5-2.6-1.92.3-2.2-1.6-1.52.0-2.6-1.51.5-1.50.3-0.3-1.61.6-2.2-1.61.4-0.2
Pavlov. Cond. magazine entry latency1.21.55.01.8-1.81.80.8-1.31.30.62.2-1.31.60.3-0.30.31.0-1.00.3-0.31.81.30.00.3
Pavlov. Cond. change in total contacts1.11.87.61.8-1.91.90.9-1.41.41.02.8-1.51.80.2-0.20.21.0-1.00.2-0.22.01.6-0.2-0.2
Pavlov. Cond. index score2.02.77.02.4-2.42.41.3-1.91.81.22.6-2.02.40.6-0.60.60.8-0.80.6-0.62.41.8-0.4-0.1
Pavlov. Cond. latency score1.72.26.72.2-2.12.21.2-1.71.61.12.6-1.82.00.5-0.50.50.7-0.70.6-0.62.21.7-0.30.0
Pavlov. Cond. lever contacts2.73.79.02.6-2.72.72.0-2.42.31.71.6-2.23.01.5-1.51.5-0.20.21.5-1.52.41.7-1.50.1
Pavlov. Cond. magazine entry number1.51.97.0-2.02.0-1.9-1.01.5-1.4-0.9-2.61.6-1.7-0.30.3-0.3-0.90.9-0.30.3-2.0-1.70.0-0.6
Pavlov. Cond. intertrial magazine entries0.50.83.9-0.40.2-0.30.5-0.00.00.3-2.00.2-0.31.0-1.01.0-1.61.71.0-1.0-0.7-0.5-0.90.2
Pavlov. Cond. lever-magazine prob. diff.1.92.56.72.3-2.32.31.3-1.81.81.12.6-1.92.20.6-0.60.60.8-0.80.6-0.62.31.8-0.40.0
Pavlov. Cond. response bias3.24.310.32.9-2.93.02.0-2.62.51.72.3-2.53.21.3-1.31.30.3-0.31.3-1.32.92.1-1.20.0
Time in closed arm before self-admin2.02.63.7-1.71.5-1.8-1.91.6-1.6-1.9-1.11.5-1.1-1.81.8-1.81.8-1.8-1.81.8-1.2-1.61.4-0.4
Time in closed arm after self-admin1.51.63.7-0.80.7-0.9-1.31.0-1.0-1.31.20.7-0.6-1.51.5-1.61.9-1.9-1.61.6-0.3-0.71.60.1
Time in open arm before self-admin0.50.61.10.7-0.60.60.7-0.70.60.5-0.9-0.40.61.1-1.11.1-0.90.91.1-1.10.20.1-0.80.4
Time in open arm after self-admin2.12.34.31.4-1.21.61.7-1.51.62.10.6-1.81.31.4-1.41.5-1.71.71.5-1.51.61.9-1.10.6
Bone: periosteal estimation0.71.52.11.5-1.21.31.3-1.41.41.40.7-1.41.21.1-1.11.1-1.11.11.1-1.11.31.3-1.11.0
Bone: periosteal perimeter0.91.52.41.4-1.11.21.4-1.31.31.20.0-1.11.11.5-1.51.5-1.41.41.5-1.50.80.9-1.30.3
Bone: post-yield work0.10.21.4-0.10.0-0.30.10.2-0.20.21.20.3-0.9-0.10.1-0.1-0.40.4-0.10.1-0.40.20.00.8
Progressive ratio test 1 active lever presses0.20.33.6-0.40.2-0.1-0.40.3-0.3-0.40.30.30.2-0.30.3-0.30.5-0.5-0.20.2-0.2-0.50.3-1.9
Progressive ratio test 1 breakpoint0.20.33.5-0.40.2-0.2-0.40.3-0.3-0.40.40.40.1-0.30.3-0.30.4-0.4-0.20.2-0.3-0.50.3-1.9
Progressive ratio test 1 inactive lever presses0.20.33.00.1-0.20.2-0.20.1-0.1-0.21.40.1-0.0-0.20.2-0.20.6-0.6-0.20.20.0-0.40.3-1.7
Progressive ratio test 2 active lever presses0.20.33.3-0.1-0.10.4-0.2-0.00.00.10.6-0.20.5-0.40.4-0.40.6-0.6-0.00.00.40.10.4-1.8
Progressive ratio test 2 breakpoint0.20.32.50.1-0.30.60.0-0.20.20.30.7-0.40.7-0.30.3-0.30.5-0.50.1-0.10.60.30.2-1.6
Progressive ratio test 2 inactive lever presses0.20.32.20.4-0.50.80.3-0.40.40.51.2-0.40.50.2-0.20.2-0.10.10.6-0.60.40.40.1-1.5
Incentive Sensitization - Responses0.10.11.4-0.10.10.3-0.00.0-0.00.2-0.3-0.10.4-0.10.1-0.10.0-0.00.3-0.30.2-0.10.2-1.2
Incentive Sensitization - Breakpoint0.10.11.2-0.0-0.00.4-0.0-0.00.10.2-0.1-0.20.5-0.10.1-0.10.1-0.10.3-0.30.3-0.00.1-1.1
Sum of active levers in priming session hrs 5-60.20.20.6-0.50.6-0.5-0.40.5-0.4-0.10.50.2-0.8-0.60.6-0.50.2-0.2-0.60.6-0.10.20.60.2
Progressive ratio0.10.10.30.1-0.3-0.3-0.0-0.10.1-0.00.3-0.20.4-0.50.5-0.50.4-0.4-0.40.40.40.3-0.4-0.0
Food seeking constrained by brief footshock0.00.00.2-0.20.2-0.2-0.10.1-0.2-0.2-0.30.3-0.3-0.10.10.00.0-0.0-0.10.1-0.3-0.3-0.10.5
Seeking ratio, punishment vs. effort0.10.10.3-0.30.50.0-0.30.3-0.4-0.4-0.60.5-0.60.1-0.10.10.1-0.10.1-0.1-0.5-0.60.50.2
Retroperitoneal fat weight3.012.920.04.5-4.54.54.0-4.24.13.62.6-3.73.93.6-3.63.6-2.22.23.7-3.73.53.2-3.51.7
Reaction time number correct2.24.36.42.4-2.31.92.3-2.22.42.52.1-2.52.11.8-1.81.8-1.91.91.5-1.52.32.4-1.61.6
Reaction time mean minus median0.51.22.00.8-0.91.31.2-1.31.31.2-0.3-1.21.41.1-1.11.1-0.80.81.1-1.11.11.0-1.30.4
Reaction time mean minus median AUC1.43.55.11.8-1.92.32.1-2.12.12.00.4-1.92.02.0-2.02.0-1.51.52.1-2.11.71.6-2.01.2
Reaction time num false alarms0.10.11.10.2-0.20.00.00.1-0.2-0.20.50.3-0.80.1-0.10.10.0-0.00.1-0.1-0.4-0.30.41.1
Reaction time num false alarms AUC0.10.21.00.1-0.1-0.1-0.20.2-0.2-0.30.60.3-0.8-0.30.3-0.30.5-0.5-0.30.3-0.2-0.20.61.0
Reaction time trials correct on left2.24.36.42.4-2.31.92.3-2.22.42.52.1-2.52.11.8-1.81.8-1.91.91.5-1.52.32.4-1.61.6
Reaction time trials on left2.34.36.52.4-2.31.92.3-2.22.42.52.1-2.52.11.8-1.81.8-1.81.81.5-1.52.32.4-1.61.6
Reaction time mean0.50.72.4-0.50.4-0.4-0.90.5-0.4-0.8-0.20.10.1-1.31.3-1.31.5-1.6-1.21.20.30.00.9-0.1
Reaction time mean AUC0.20.31.1-0.30.1-0.1-0.40.1-0.1-0.4-0.2-0.20.3-0.80.8-0.81.1-1.1-0.70.70.50.20.40.1
Median of all reaction times1.72.45.3-1.21.1-1.2-1.71.3-1.2-1.6-0.30.8-0.7-2.12.1-2.12.3-2.3-2.02.0-0.3-0.61.7-0.5
Reaction time omissions0.50.81.51.1-0.91.20.9-1.11.00.70.3-0.80.81.1-1.11.1-0.40.41.0-1.00.70.6-0.90.3
Reaction time false alarm rate0.81.22.3-0.91.0-0.9-1.21.1-1.2-1.3-0.61.4-1.5-1.01.0-1.01.2-1.2-0.80.8-1.2-1.31.10.0
Reaction time premature initiation rate1.01.44.5-0.60.4-0.6-1.20.7-0.8-1.21.00.8-0.5-1.61.6-1.62.1-2.1-1.51.5-0.3-0.70.9-0.7
Reaction time premature initiations0.30.64.00.6-0.70.40.0-0.40.40.12.0-0.60.6-0.60.6-0.61.1-1.1-0.70.71.00.60.10.4
Std. dev. reaction times0.61.02.30.9-0.91.31.0-1.31.30.9-0.5-1.21.50.9-0.90.9-0.40.41.0-1.01.20.9-1.10.6
Reaction time trials completed2.34.36.52.4-2.31.92.3-2.22.42.52.1-2.52.11.8-1.81.8-1.81.81.5-1.52.32.4-1.61.6
Reaction time trials AUC2.14.16.82.4-2.41.92.2-2.22.42.42.4-2.62.21.5-1.51.5-1.51.51.3-1.32.52.6-1.41.5
Run reversals in cocaine runway, females0.20.20.90.2-0.10.10.4-0.20.30.60.9-0.4-0.30.2-0.20.2-0.60.60.1-0.10.30.8-0.20.4
Run reversals in cocaine runway, males1.31.33.1-1.21.0-1.2-1.31.4-1.4-1.2-0.51.3-1.0-1.11.1-1.10.8-0.8-1.11.1-1.2-1.01.3-1.8
Latency to leave start box in cocaine runway0.20.20.70.2-0.3-0.0-0.1-0.10.1-0.20.8-0.20.5-0.60.6-0.60.8-0.8-0.50.50.40.1-0.0-0.6
Latency to leave start box in cocaine runway, F0.30.40.8-0.80.6-0.9-0.60.7-0.7-0.7-0.60.7-0.4-0.60.6-0.60.3-0.3-0.60.6-0.7-0.70.1-0.0
Latency to leave start box in cocaine runway, M1.61.57.21.6-1.61.40.7-1.21.20.82.7-1.41.5-0.10.1-0.11.0-1.0-0.10.11.91.5-0.2-0.9
Std. dev. time between licks in bursts1.31.73.20.9-1.01.01.4-1.21.11.2-1.1-0.81.11.7-1.71.7-1.81.81.7-1.70.40.3-1.60.4
Total sessions with >9 infusions0.80.95.7-1.11.1-0.9-0.70.7-0.9-1.0-2.41.1-0.4-0.00.0-0.0-0.00.0-0.10.1-1.3-1.6-0.2-1.6
Short access day 1 total inactive lever presses0.91.23.70.6-0.70.41.2-0.70.70.9-0.4-0.30.41.5-1.51.5-1.91.91.3-1.3-0.2-0.1-1.50.2
Short access day 10 total inactive lever presses1.12.611.71.9-1.71.81.6-1.61.61.83.4-1.50.31.1-1.11.1-0.90.91.1-1.11.52.1-0.72.2
Short access day 1 total infusions0.81.05.5-1.31.3-1.2-0.81.0-1.1-0.9-2.31.2-1.1-0.20.2-0.2-0.30.3-0.20.2-1.5-1.40.1-0.6
Short access day 10 total infusions0.30.31.9-0.70.5-0.5-0.50.4-0.4-0.6-0.90.5-0.1-0.30.3-0.30.4-0.4-0.30.3-0.5-0.9-0.1-1.4
Short access total infusions0.40.55.0-1.00.9-0.7-0.60.6-0.6-0.6-2.20.6-0.1-0.10.1-0.1-0.10.1-0.10.1-0.8-1.0-0.2-0.8
Short access day 1 locomotion1.11.34.1-1.31.3-1.2-1.21.2-1.3-1.5-2.01.4-1.4-0.60.6-0.60.7-0.7-0.70.7-1.4-1.60.8-0.4
Short access day 10 total locomotion0.81.45.2-0.20.10.10.8-0.10.10.7-1.80.3-0.41.5-1.51.5-2.32.31.7-1.7-1.0-0.6-1.2-0.1
Short access total locomotion0.70.83.6-0.20.2-0.00.3-0.1-0.1-0.2-1.90.6-0.21.1-1.11.1-1.11.11.0-1.0-1.0-1.1-1.0-1.0
One hour access (0.3 mA shock)0.50.64.10.1-0.30.30.1-0.10.30.72.0-0.90.8-0.50.5-0.50.2-0.2-0.40.41.11.00.8-1.6
Compulsive drug intake0.50.62.90.5-0.60.30.5-0.60.80.70.7-1.20.80.0-0.00.0-0.10.1-0.20.21.31.4-0.11.7
One hour access (shock baseline)0.40.68.9-0.1-0.00.2-0.30.2-0.2-0.21.20.20.4-0.30.3-0.30.6-0.6-0.10.1-0.0-0.40.6-3.0
Social response proportion1.51.79.81.2-0.91.3-0.0-0.80.80.43.1-1.20.6-0.70.7-0.72.0-2.0-0.80.81.91.71.0-0.2
Social responses1.62.19.10.10.30.3-1.30.4-0.4-1.01.5-0.0-0.1-1.81.8-1.83.0-3.0-1.61.60.90.32.0-0.6
Social time0.30.51.40.5-0.60.60.1-0.40.50.31.0-0.81.1-0.50.5-0.51.0-1.0-0.30.31.20.60.1-0.8
Soleus weight0.10.41.70.3-0.60.3-0.1-0.10.2-0.00.7-0.50.8-0.70.7-0.71.0-1.0-0.70.70.80.50.51.3
Bone: stiffness1.32.24.91.9-2.01.71.6-1.61.61.52.2-1.51.31.2-1.21.2-0.80.81.1-1.11.51.5-1.11.7
Tibialis anterior weight0.31.13.31.1-1.41.10.5-0.91.00.71.7-1.41.5-0.30.3-0.30.9-0.9-0.30.31.81.40.31.5
Time to tail flick, vehicle, before self-admin0.40.43.1-0.10.2-0.10.3-0.20.10.1-1.80.20.00.6-0.60.6-0.80.80.7-0.7-0.5-0.3-1.01.1
Time to tail flick, vehicle, after self-admin0.20.31.80.0-0.10.10.4-0.30.30.5-1.4-0.51.00.4-0.40.3-0.70.70.4-0.40.30.1-0.6-0.8
Time to tail flick, test, before self-admin0.10.10.70.00.0-0.0-0.0-0.10.0-0.2-0.20.10.2-0.10.1-0.00.2-0.2-0.00.0-0.1-0.3-0.30.8
Time to tail flick, test, after self-admin0.60.61.80.8-1.00.80.9-0.90.90.8-0.1-0.81.30.7-0.70.6-0.60.60.8-0.80.70.6-1.0-0.4
Delta time to tail flick, vehicle, before/after SA1.41.42.81.3-1.31.31.2-1.21.41.51.3-1.61.50.8-0.80.6-0.70.70.7-0.71.71.6-0.5-0.1
Delta time to tail flick, test, before/after SA0.20.21.30.2-0.40.30.3-0.20.30.4-0.5-0.30.60.3-0.30.3-0.20.20.3-0.30.20.2-0.3-1.1
Tibia length0.61.83.81.5-1.21.31.3-1.31.00.90.3-0.40.41.9-1.91.9-1.41.41.9-1.90.00.1-1.60.8
Ambulatory time before self-admin0.50.71.30.6-0.80.81.0-0.80.81.0-0.0-0.70.70.9-0.90.8-1.11.11.1-1.10.50.4-1.10.3
Ambulatory time after self-admin0.20.30.9-0.20.1-0.1-0.40.2-0.2-0.30.6-0.0-0.3-0.60.6-0.60.8-0.8-0.60.60.30.20.60.9
Bone: tissue strength0.40.40.80.5-0.60.40.7-0.30.30.50.7-0.0-0.40.8-0.80.8-0.90.90.8-0.8-0.20.1-0.40.5
Total heroin consumption0.60.71.8-1.21.3-1.0-0.61.0-1.0-0.5-1.31.1-1.3-0.20.2-0.3-0.50.5-0.10.1-1.3-0.90.2-0.1
Bone: trabecular number1.83.05.01.8-1.91.82.0-1.82.02.21.7-2.11.61.4-1.41.4-1.51.51.3-1.31.92.2-1.41.7
Bone: trabecular spacing1.11.43.3-0.91.3-0.9-1.41.1-1.2-1.7-1.81.4-0.6-0.80.8-0.81.2-1.2-0.70.7-1.3-1.70.8-1.4
Bone: trabecular thickness0.20.30.8-0.30.4-0.3-0.40.2-0.00.10.1-0.40.3-0.90.9-0.90.6-0.6-0.90.90.60.50.4-0.3
Bone: trabecular tissue density2.02.95.1-2.12.3-2.1-1.82.0-1.8-1.10.41.4-2.2-2.12.1-2.10.9-0.9-2.12.1-1.3-0.61.9-0.1
Water consumed over 24 hours0.20.31.0-0.20.2-0.2-0.60.3-0.3-0.60.20.00.0-0.70.7-0.71.0-1.0-0.80.80.2-0.10.8-0.4
Number of responses in last shaping day0.60.62.1-0.80.8-0.7-0.80.8-0.9-1.1-1.01.0-1.0-0.30.3-0.30.6-0.6-0.40.4-1.0-1.50.60.8