LOC102556485

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression LOC102556485 0.05 0.04 6.3e-05 0.03 0.04 0.03 0.03 3.5e-04 1.5e-04 1.9e-03 9.7e-04
2 pVTA gene expression LOC102556485 0.09 0.06 3.9e-04 0.07 0.07 0.04 0.06 5.1e-04 7.6e-04 8.2e-03 1.7e-03
3 Liver gene expression LOC102556485 0.04 0.03 1.5e-06 0.04 0.04 0.03 0.03 2.6e-05 3.7e-05 6.1e-04 1.2e-04
4 NAcc mRNA stability LOC102556485 0.04 0.04 3.9e-03 0 0.01 0.01 0.01 3.4e-01 6.5e-03 2.4e-02 2.9e-02
5 Adipose gene expression LOC102556485 0.02 0.02 1.7e-03 0.01 0.01 0.01 0.01 9.2e-03 7.4e-03 3.1e-02 1.6e-02
6 PL mRNA stability LOC102556485 0.02 0.02 1.2e-03 0.03 0.02 0.01 0.02 6.4e-04 2.0e-03 9.6e-03 1.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density0.00.10.10.20.2-0.2-0.40.1-0.1
Area under the delay curve2.12.32.7-1.6-1.61.51.3-1.6-1.4
BMI with tail0.72.35.21.21.7-1.1-1.11.32.3
BMI without tail2.04.25.71.92.3-1.8-2.01.92.4
Body weight7.230.232.95.65.7-5.3-5.15.55.7
Weight adjusted by age0.30.40.70.60.7-0.5-0.30.70.9
Bone surface0.00.10.2-0.2-0.10.30.2-0.3-0.4
Bone volume0.00.00.00.00.00.10.0-0.2-0.2
Breakpoint value in progressive ratio session0.00.00.10.30.2-0.0-0.30.1-0.4
Number of licking bursts0.10.20.3-0.4-0.40.40.6-0.3-0.1
Context. condit. distance diff. score0.00.00.20.20.1-0.10.10.0-0.5
Locomotion velocity, session 10.00.00.1-0.2-0.10.30.1-0.3-0.0
Locomotion distance, session 10.91.21.81.11.3-1.0-1.30.90.8
Locomotion velocity, session 20.20.30.5-0.4-0.40.70.5-0.6-0.5
Locomotion distance, session 20.00.00.10.00.20.0-0.3-0.20.2
Locomotion velocity, session 30.10.10.30.30.5-0.2-0.50.10.4
Locomotion distance, session 30.70.81.4-0.8-0.81.00.8-1.2-0.8
Stereotopy head waving bouts, day 30.10.10.20.20.2-0.30.10.50.5
Stereotopy head waving duration, day 30.30.40.70.50.5-0.7-0.40.80.8
Locomotion velocity, session 70.40.40.70.60.6-0.6-0.90.40.6
Locomotion distance, session 70.40.50.8-0.8-0.70.70.5-0.9-0.5
Stereotopy head waving bouts, day 70.20.20.3-0.4-0.40.40.2-0.5-0.5
Stereotopy head waving duration, day 70.10.10.30.40.4-0.4-0.60.30.2
Locomotion velocity, session 80.30.30.70.80.8-0.4-0.60.30.3
Locomotion distance, session 80.30.40.80.70.9-0.5-0.90.40.4
Degree of sensitization distance1.21.21.51.01.0-1.1-1.11.21.0
Degree of sensitization stereotypy0.10.10.2-0.2-0.20.2-0.2-0.3-0.5
Conditioned locomotion3.23.74.1-2.0-2.01.81.8-2.0-2.0
Cocaine response after cond. corrected0.40.51.60.40.4-0.6-0.30.71.3
Cocaine response after cond. not corrected2.12.33.91.41.4-1.5-1.21.62.0
Cocaine response before conditioning1.11.31.91.31.4-1.1-1.21.10.7
Saline control response1.51.92.61.31.3-1.6-1.61.31.2
Bone: connectivity density0.30.40.9-0.7-0.60.50.4-0.7-1.0
Bone: cortical apparent density0.60.82.4-0.5-0.70.70.6-0.8-1.5
Bone: cortical area0.10.20.5-0.2-0.40.40.7-0.3-0.7
Bone: cortical porosity0.10.10.2-0.4-0.40.0-0.2-0.3-0.4
Bone: cortical porosity0.20.20.4-0.7-0.60.20.0-0.4-0.5
Bone: cortical thickness0.10.20.50.70.4-0.30.00.4-0.2
Bone: cortical thickness0.00.00.00.10.1-0.1-0.10.1-0.1
Bone: cortical tissue density0.60.82.5-0.5-0.70.70.6-0.8-1.6
Condit. Reinf. active minus inactive responses0.10.10.10.30.2-0.3-0.20.40.2
Condit. Reinf. active-inactive response ratio0.20.20.40.50.4-0.5-0.30.60.5
Condit. Reinf. active responses0.00.00.1-0.3-0.20.20.2-0.2-0.1
Condit. Reinf. inactive responses0.70.91.1-1.0-0.91.00.9-1.0-0.7
Incentive salience index mean0.00.10.1-0.3-0.20.30.2-0.2-0.1
Condit. Reinf. lever presses1.31.72.1-1.4-1.21.41.2-1.4-1.1
Condit. Reinf. active minus inactive responses2.32.93.81.91.8-1.8-1.51.71.5
Condit. Reinf. active-inactive response ratio2.02.13.11.41.4-1.4-1.21.41.8
Condit. Reinf. active responses1.82.63.41.91.6-1.7-1.41.61.4
Condit. Reinf. inactive responses0.10.10.30.1-0.10.10.2-0.1-0.6
Condit. Reinf. lever presses2.63.54.52.12.0-2.0-1.71.81.5
Condit. Reinf. lever reinforcers received2.23.03.92.01.8-1.9-1.51.81.4
Conditioned reinforcement - actives0.20.20.9-0.40.00.00.3-0.3-1.0
Conditioned reinforcement - inactives0.70.81.5-0.9-0.80.71.2-0.7-1.1
Conditioned locomotion0.30.30.6-0.8-0.30.40.3-0.6-0.8
Patch foraging indifference point 0 sec1.11.82.61.31.1-1.6-1.61.31.0
Patch foraging indifference point AUC0.10.10.20.30.2-0.4-0.5-0.0-0.4
Delay disc. indifference point, 0s delay0.00.00.1-0.2-0.10.10.0-0.10.2
Delay disc. indifference point, 16s delay1.01.01.3-1.1-1.11.00.9-1.1-0.9
Delay disc. indifference point, 2s delay0.30.30.4-0.6-0.60.50.5-0.6-0.6
Delay disc. indifference point, 24s delay0.90.91.0-1.0-0.90.80.9-1.0-1.0
Delay disc. indifference point, 4s delay2.32.52.6-1.6-1.61.51.5-1.6-1.6
Delay disc. indifference point, 8s delay2.02.02.5-1.6-1.51.41.3-1.6-1.2
Indifference point function ln k0.10.10.4-0.4-0.20.70.4-0.30.2
Indifference point function log k0.10.10.4-0.4-0.20.70.4-0.30.2
Patch foraging total patch changes 0 sec1.32.23.01.51.2-1.7-1.61.51.2
Patch foraging total patch changes 12 sec0.70.91.81.10.7-1.3-1.10.9-0.2
Patch foraging total patch changes 18 sec2.83.65.52.01.9-2.4-2.11.80.9
Patch foraging total patch changes 24 sec2.83.44.42.01.8-2.1-1.91.91.3
Patch foraging total patch changes 6 sec0.10.10.40.30.1-0.5-0.60.2-0.1
Patch foraging time to switch 0 sec0.20.30.4-0.6-0.60.50.7-0.4-0.3
Patch foraging water rate 0 sec0.20.30.50.70.7-0.6-0.50.6-0.0
Patch foraging water rate 12 sec0.30.50.80.70.8-0.4-0.70.80.9
Patch foraging water rate 18 sec0.20.31.50.10.2-0.1-0.00.41.2
Patch foraging water rate 24 sec0.70.91.30.91.0-0.9-0.91.01.2
Patch foraging water rate 6 sec0.30.40.70.80.9-0.4-0.70.60.3
Seeking ratio, delayed vs. immediate footshock1.82.13.4-1.8-1.41.51.4-1.6-0.7
Distance traveled before self-admin0.10.10.30.20.4-0.20.10.40.5
Distance traveled after self-admin0.30.30.8-0.4-0.50.50.6-0.4-0.9
Extensor digitorum longus weight0.10.50.9-0.7-0.70.60.9-0.6-0.2
Bone: elastic displacement0.10.10.30.40.2-0.50.00.3-0.3
Bone: elastic work0.60.71.41.21.0-1.0-0.60.90.2
Bone: endosteal estimation0.20.40.90.40.4-0.6-0.60.51.0
Bone: endosteal perimeter1.02.02.6-1.6-1.51.51.4-1.5-0.9
Epididymis fat weight0.40.81.80.70.8-0.9-0.80.81.3
Delta time in closed arm before/after self-admin0.10.10.2-0.5-0.30.30.2-0.30.5
Delta time in open arm before/after self-admin0.30.30.40.70.6-0.5-0.50.3-0.7
Diff in mean of infusions in LGA sessions0.00.00.2-0.0-0.20.20.4-0.0-0.1
Delay discount exponential model param2.52.73.11.71.7-1.6-1.51.81.5
Extinction: sum of active levers before priming0.10.10.40.10.3-0.2-0.40.20.6
Active lever presses in extinction session 60.50.51.20.50.7-0.5-0.80.61.1
Bone: final force0.81.21.71.31.2-1.1-0.91.21.0
Bone: final moment1.01.72.21.51.4-1.2-1.11.41.2
Food consumed during 24 hour testing period1.62.02.51.31.4-1.4-1.31.51.6
Glucose0.30.40.70.50.6-0.6-0.80.50.7
Heart weight2.02.93.81.91.7-1.6-1.52.01.4
Delay discount hyperbolic model param2.52.73.11.71.7-1.6-1.51.81.6
Intermittent access intake day 1-15 change0.40.40.9-0.5-0.50.41.0-0.4-0.8
Intermittent access intake escalation0.30.30.6-0.4-0.40.30.8-0.3-0.7
Intermittent access intake escalation 20.10.10.20.40.4-0.40.20.4-0.3
Intermitt. access day 1 inactive lever presses0.00.00.0-0.1-0.00.00.0-0.00.0
Intermitt. access day 15 inactive lever presses0.80.91.4-0.9-0.91.11.2-0.8-0.8
Intermitt. access escalation Index0.10.10.4-0.00.00.1-0.3-0.00.6
Intermittent access day 1 total infusions0.00.00.0-0.10.00.0-0.0-0.00.0
Intermittent access day 15 total infusions0.10.10.2-0.4-0.20.20.5-0.3-0.4
Intermittent access terminal intake (last 3 days)0.00.00.0-0.20.0-0.00.2-0.1-0.2
Intermittent access total infusions0.20.20.3-0.5-0.30.30.5-0.4-0.3
Intermittent access day 1 locomotion0.10.10.3-0.4-0.30.40.2-0.3-0.5
Intermittent access day 15 total locomotion0.40.40.7-0.9-0.60.60.5-0.7-0.7
Intermittent access total locomotion0.91.01.5-1.2-0.90.90.8-1.1-0.9
Intermittent access standard deviation0.40.40.60.80.6-0.7-0.10.7-0.5
Left kidney weight0.61.83.01.11.4-0.9-1.61.11.7
Right kidney weight0.20.72.00.40.7-0.5-0.90.51.4
Cocaine induced anxiety0.50.60.9-0.8-0.70.70.9-0.7-0.8
Post-drug Anxiety0.40.40.5-0.7-0.70.70.7-0.5-0.6
Baseline Anxiety0.20.20.3-0.4-0.50.50.3-0.4-0.3
Tail length6.419.521.84.74.5-4.6-4.54.53.7
Length with tail9.233.637.26.15.9-5.9-5.85.95.2
Length without tail6.714.715.94.03.9-3.8-3.73.93.7
Times rat made contact with spout0.40.40.80.50.6-0.6-0.60.70.9
Lifetime Intake0.10.20.3-0.5-0.30.30.4-0.4-0.4
Liver weight, left0.00.10.2-0.00.1-0.2-0.50.10.2
Liver weight, right1.22.02.41.21.5-1.3-1.51.31.5
Locomotor activity5.99.310.63.33.2-3.1-3.13.22.4
Locomotor testing distance5.79.511.13.23.3-3.0-3.13.22.5
Locomotor testing rearing0.40.50.70.70.8-0.7-0.70.90.5
Locomotion in novel chamber0.10.10.3-0.3-0.30.20.5-0.3-0.5
Locomotion in novel chamber post-restriction0.80.91.31.01.2-1.0-1.10.90.4
Fecal boli incidents, locomotor time 10.50.50.70.80.7-0.7-0.60.70.7
Change in fecal boli incidents, locomotor task0.00.00.10.10.2-0.2-0.30.10.2
Time >=10cm from walls, locomotor time 10.20.20.3-0.5-0.50.60.2-0.5-0.2
Bouts of movement, locomotor time 10.00.00.10.20.1-0.0-0.00.1-0.3
Total resting periods, locomotor time 10.00.00.00.20.1-0.1-0.10.1-0.2
Rest time, locomotor task time 10.40.40.7-0.9-0.60.70.6-0.7-0.5
Distance moved, locomotor task time 11.51.62.11.51.2-1.3-1.11.31.1
Vertical activity count, locomotor time 10.60.60.80.90.8-0.8-0.80.80.6
Time >=10cm from walls, locomotor time 21.41.51.81.31.1-1.1-1.31.21.3
Bouts of movement, locomotor time 20.00.00.10.30.1-0.1-0.00.20.3
Total resting periods, locomotor time 20.00.00.00.0-0.10.10.2-0.00.0
Rest time, locomotor task time 20.00.00.2-0.10.20.00.0-0.2-0.4
Distance moved, locomotor task time 20.70.81.10.90.6-0.9-0.81.01.1
Vertical activity count, locomotor time 20.00.00.10.1-0.1-0.1-0.20.20.3
Light reinforcement 10.51.01.20.90.9-0.9-1.11.01.0
Light reinforcement 20.20.30.6-0.7-0.40.80.1-0.50.3
Bone: marrow area0.20.41.00.40.5-0.6-0.60.51.0
Bone: maximum diameter0.40.71.1-0.7-0.80.91.0-0.8-0.8
Bone: maximum force0.71.21.51.21.1-1.1-1.01.11.1
Bone: maximum moment0.81.41.71.31.2-1.2-1.01.21.2
Mean time between licks in bursts0.91.21.6-1.1-1.11.01.3-1.1-1.0
Mean num. licks in bursts0.50.61.00.70.8-0.9-1.00.70.7
Cd content in liver2.42.63.31.71.5-1.8-1.51.81.4
Co content in liver0.10.10.10.30.2-0.20.00.20.4
Cu content in liver4.25.15.62.22.2-2.4-2.32.32.1
Fe content in liver1.51.82.61.61.2-1.5-1.21.51.0
K content in liver0.70.61.21.11.0-0.7-0.80.60.3
Mg content in liver0.10.10.10.40.30.1-0.0-0.2-0.3
Mn content in liver0.70.81.31.11.1-0.8-1.00.70.4
Na content in liver0.30.30.50.70.4-0.7-0.50.5-0.6
Rb content in liver1.01.31.91.20.9-1.4-0.91.30.9
Se content in liver0.00.00.10.30.00.10.0-0.1-0.1
Sr content in liver0.10.10.20.00.3-0.0-0.20.00.5
Zn content in liver5.25.87.62.32.4-2.3-2.42.22.8
Bone: minimum diameter0.20.50.6-0.8-0.70.80.8-0.7-0.3
Time in familiar zone, hab. session 11.21.21.5-1.0-1.20.91.2-0.9-1.2
Time in novel zone, hab. session 10.50.51.00.50.7-0.6-0.70.61.0
Total zone transitions, hab. session 10.81.12.10.81.1-0.8-1.20.81.5
Total locomotion distance, hab. session 10.30.40.70.50.6-0.5-0.70.50.8
Locomotion velocity, hab. session 10.30.40.60.60.7-0.5-0.80.40.7
Time in familiar zone, hab. session 20.50.51.0-0.3-0.60.50.8-0.6-1.0
Time in novel zone, hab. session 20.10.10.3-0.10.1-0.2-0.30.20.5
Total zone transitions, hab. session 20.10.20.30.20.5-0.1-0.50.20.6
Total locomotion distance, hab. session 20.20.30.50.60.7-0.5-0.70.40.3
Locomotion velocity, hab. session 20.10.20.30.50.5-0.3-0.60.30.1
Novel to familiar place preference ratio1.01.02.10.80.9-1.0-1.40.81.0
Novelty place preference1.01.02.10.70.9-1.0-1.40.81.0
Time in novel zone, NPP test1.31.32.40.91.0-1.1-1.51.01.2
Total zone transitions, NPP test2.73.85.11.72.2-1.6-2.11.72.2
Total locomotion distance, NPP test1.01.31.61.11.3-1.0-1.21.01.2
Locomotion velocity, NPP test1.01.41.81.21.3-1.0-1.31.01.2
Intraocular pressure1.11.61.91.11.2-1.4-1.21.31.4
Delta distance traveled before/after self-admin0.40.51.0-0.5-0.80.70.4-0.6-1.0
Delta ambulatory time before/after self-admin0.10.10.30.50.1-0.3-0.60.3-0.1
Parametrial fat weight0.81.62.11.21.3-1.2-1.51.31.2
Pavlov. Cond. lever latency5.16.57.52.52.4-2.7-2.52.72.5
Pavlov. Cond. magazine entry latency6.78.610.9-2.7-2.72.93.0-2.9-3.3
Pavlov. Cond. change in total contacts1.81.93.2-1.1-1.31.31.3-1.4-1.8
Pavlov. Cond. index score6.68.410.2-2.7-2.72.92.9-2.9-3.2
Pavlov. Cond. latency score6.48.19.4-2.6-2.72.92.8-2.9-3.1
Pavlov. Cond. lever contacts3.03.54.0-1.8-1.72.01.8-2.0-1.8
Pavlov. Cond. magazine entry number7.69.511.82.92.9-3.1-3.13.13.4
Pavlov. Cond. intertrial magazine entries0.40.50.60.70.7-0.7-0.70.70.6
Pavlov. Cond. lever-magazine prob. diff.6.07.49.4-2.5-2.52.82.8-2.7-3.1
Pavlov. Cond. response bias7.28.810.4-2.8-2.83.03.0-2.9-3.2
Pavlov. Cond. lever latency0.60.81.2-1.0-1.01.10.8-0.8-0.6
Pavlov. Cond. magazine entry latency0.10.10.6-0.1-0.10.20.3-0.3-0.8
Pavlov. Cond. change in total contacts2.83.85.02.22.1-2.2-1.82.01.3
Pavlov. Cond. index score0.20.20.40.60.5-0.6-0.30.4-0.1
Pavlov. Cond. latency score0.10.10.30.50.5-0.4-0.20.3-0.2
Pavlov. Cond. lever contacts1.21.62.01.41.3-1.4-1.21.21.0
Pavlov. Cond. magazine entry number0.30.31.00.30.4-0.3-0.60.51.0
Pavlov. Cond. intertrial magazine entries0.40.50.7-0.7-0.80.80.6-0.6-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.30.60.5-0.5-0.20.3-0.1
Pavlov. Cond. response bias0.20.20.40.60.5-0.6-0.30.40.1
Time in closed arm before self-admin2.02.33.21.51.8-1.6-1.41.61.1
Time in closed arm after self-admin0.10.10.60.10.3-0.1-0.20.30.8
Time in open arm before self-admin1.41.52.0-1.4-1.41.41.2-1.2-0.5
Time in open arm after self-admin0.50.51.8-0.4-0.50.40.1-0.7-1.3
Bone: periosteal estimation0.00.10.20.30.2-0.2-0.10.20.4
Bone: periosteal perimeter1.01.72.1-1.3-1.41.41.4-1.3-1.1
Bone: post-yield work0.10.10.60.10.2-0.1-0.30.20.8
Progressive ratio test 1 active lever presses0.00.00.1-0.10.3-0.2-0.30.00.0
Progressive ratio test 1 breakpoint0.00.00.0-0.20.2-0.1-0.2-0.10.1
Progressive ratio test 1 inactive lever presses0.40.41.0-0.6-0.30.50.7-0.5-1.0
Progressive ratio test 2 active lever presses0.70.70.9-0.9-0.70.80.9-0.9-0.9
Progressive ratio test 2 breakpoint0.50.60.7-0.9-0.70.70.8-0.8-0.7
Progressive ratio test 2 inactive lever presses1.71.92.7-1.3-1.11.31.6-1.2-1.5
Incentive Sensitization - Responses1.81.82.2-1.3-1.41.41.5-1.3-1.2
Incentive Sensitization - Breakpoint1.71.82.2-1.3-1.31.41.5-1.2-1.2
Sum of active levers in priming session hrs 5-60.30.30.50.60.6-0.6-0.70.50.3
Progressive ratio4.04.65.12.02.2-2.3-2.22.11.9
Food seeking constrained by brief footshock0.50.60.9-0.9-0.90.80.9-0.8-0.2
Seeking ratio, punishment vs. effort5.46.67.6-2.6-2.82.72.8-2.5-1.9
Retroperitoneal fat weight0.61.82.81.31.1-1.3-1.51.31.7
Reaction time number correct0.20.30.6-0.8-0.60.60.6-0.5-0.3
Reaction time mean minus median0.00.00.10.10.2-0.0-0.30.10.1
Reaction time mean minus median AUC0.20.30.40.30.6-0.4-0.60.50.6
Reaction time num false alarms0.20.30.4-0.6-0.60.50.5-0.6-0.5
Reaction time num false alarms AUC0.10.10.2-0.4-0.40.20.1-0.3-0.2
Reaction time trials correct on left0.20.30.6-0.8-0.60.60.6-0.5-0.3
Reaction time trials on left0.30.40.6-0.8-0.60.60.7-0.5-0.3
Reaction time mean0.00.00.00.10.1-0.2-0.10.1-0.2
Reaction time mean AUC0.00.00.0-0.1-0.0-0.1-0.10.0-0.0
Median of all reaction times0.00.00.10.1-0.0-0.2-0.10.1-0.2
Reaction time omissions0.40.50.8-0.8-0.90.50.7-0.6-0.8
Reaction time false alarm rate0.00.00.1-0.2-0.30.10.1-0.2-0.2
Reaction time premature initiation rate1.31.72.31.51.2-1.3-1.51.40.6
Reaction time premature initiations0.50.71.00.90.8-0.8-1.01.00.5
Std. dev. reaction times0.10.10.30.20.4-0.4-0.50.30.3
Reaction time trials completed0.30.40.6-0.8-0.60.60.7-0.5-0.3
Reaction time trials AUC0.30.50.8-0.9-0.70.70.7-0.6-0.4
Run reversals in cocaine runway, females2.12.12.8-1.5-1.51.71.5-1.4-1.0
Run reversals in cocaine runway, males0.20.20.50.70.4-0.3-0.30.5-0.5
Latency to leave start box in cocaine runway0.20.20.40.60.4-0.6-0.40.5-0.2
Latency to leave start box in cocaine runway, F1.01.12.01.41.1-1.2-0.81.20.2
Latency to leave start box in cocaine runway, M0.50.40.7-0.7-0.70.60.4-0.8-0.6
Std. dev. time between licks in bursts3.03.64.7-1.9-1.91.92.2-1.8-1.5
Total sessions with >9 infusions0.00.00.1-0.2-0.20.10.30.10.3
Short access day 1 total inactive lever presses2.42.73.3-1.8-1.51.61.8-1.6-1.5
Short access day 10 total inactive lever presses0.10.10.3-0.0-0.20.20.5-0.1-0.5
Short access day 1 total infusions0.80.81.0-1.0-0.90.90.9-0.8-0.8
Short access day 10 total infusions0.00.00.2-0.10.1-0.1-0.10.00.4
Short access total infusions0.30.30.6-0.8-0.50.50.5-0.6-0.4
Short access day 1 locomotion0.00.00.1-0.3-0.10.10.0-0.00.3
Short access day 10 total locomotion0.10.10.30.00.3-0.3-0.50.20.5
Short access total locomotion0.00.00.1-0.30.1-0.1-0.3-0.00.2
One hour access (0.3 mA shock)0.00.00.1-0.3-0.00.0-0.0-0.2-0.3
Compulsive drug intake0.00.00.1-0.2-0.20.2-0.1-0.20.2
One hour access (shock baseline)0.10.10.40.00.2-0.20.10.0-0.6
Social response proportion0.20.20.30.50.4-0.5-0.50.50.1
Social responses0.30.40.60.50.7-0.6-0.70.50.7
Social time0.81.01.6-1.0-1.01.11.3-0.8-0.9
Soleus weight4.212.415.43.53.6-3.3-3.33.43.9
Bone: stiffness0.10.20.30.50.4-0.3-0.40.40.5
Tibialis anterior weight0.10.21.10.20.2-0.3-0.00.31.1
Time to tail flick, vehicle, before self-admin2.22.22.91.31.5-1.4-1.41.51.7
Time to tail flick, vehicle, after self-admin0.40.40.80.90.6-0.9-0.50.7-0.2
Time to tail flick, test, before self-admin0.10.10.2-0.3-0.30.3-0.3-0.10.4
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.30.20.5-0.3-0.3
Delta time to tail flick, vehicle, before/after SA0.90.82.4-0.5-0.80.60.9-0.8-1.5
Delta time to tail flick, test, before/after SA0.10.10.2-0.1-0.1-0.00.5-0.3-0.4
Tibia length6.919.422.54.64.7-4.1-4.44.34.3
Ambulatory time before self-admin0.00.00.1-0.10.20.00.30.10.3
Ambulatory time after self-admin0.10.10.2-0.1-0.20.30.1-0.2-0.4
Bone: tissue strength3.23.14.32.11.8-1.8-1.51.91.4
Total heroin consumption0.91.01.61.30.9-1.0-1.01.20.6
Bone: trabecular number0.50.91.3-0.9-0.80.90.7-1.0-1.1
Bone: trabecular spacing1.11.51.91.31.2-1.1-1.11.41.2
Bone: trabecular thickness0.00.10.20.20.2-0.1-0.3-0.1-0.4
Bone: trabecular tissue density0.20.30.40.50.5-0.3-0.60.40.6
Water consumed over 24 hours0.00.10.2-0.1-0.00.10.30.10.5
Number of responses in last shaping day0.40.40.9-0.7-0.70.70.9-0.6-0.2