Hub : Traits

Bone: cortical area

Tags: Physiology · Bone

Project: r01_doug_adams

5 loci · 5 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	269012498	270410413	1	1	1.93e-07	2.91e-07	1.00e+00	Cacul1
2	chr8	117463629	118343328	1	1	7.67e-32	3.97e-02	1.00e+00	Mst1
3	chr9	83390749	84777604	1	1	0.00e+00	5.58e-01	1.00e+00	Retreg2
4	chr10	106916192	107706829	1	1	3.96e-09	1.23e-09	2.09e-02	Zfp950l6
5	chr16	18261710	19650658	1	1	1.55e-07	2.31e-05	5.22e-01	Uba52

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	229.69	4	2	40	-0.95	5.00e-02	Cacul1 Retreg2 Uba52 Zfp950l6
BMI without tail	14320.37	4	2	40	0.99	5.35e-03	Cacul1 Retreg2 Uba52 Zfp950l6
Body weight	13.51	5	4	80	0.3	6.25e-01	Cacul1 Mst1 Retreg2 Uba52 Zfp950l6
Epididymis fat weight	9087.87	4	3	60	0.99	1.11e-02	Cacul1 Mst1 Retreg2 Uba52
Glucose	226.15	3	2	40	0	1.00e+00	Cacul1 Mst1 Retreg2
Heart weight	1542.91	2	2	40	0	1.00e+00	Cacul1 Retreg2
Left kidney weight	13766.06	4	2	40	-0.99	9.66e-03	Cacul1 Retreg2 Uba52 Zfp950l6
Right kidney weight	8088.1	5	3	60	-0.97	4.77e-03	Cacul1 Mst1 Retreg2 Uba52 Zfp950l6
Tail length	9641.4	3	1	20	0	1.00e+00	Mst1 Retreg2 Uba52
Length with tail	376.04	4	2	40	1	1.46e-03	Cacul1 Mst1 Retreg2 Uba52
Length without tail	11814.43	4	2	40	-0.98	1.66e-02	Cacul1 Mst1 Retreg2 Uba52
Liver weight, left	1176.77	3	3	60	0	1.00e+00	Cacul1 Mst1 Retreg2
Liver weight, right	33.38	3	2	40	0	1.00e+00	Cacul1 Mst1 Retreg2
Parametrial fat weight	116.25	2	2	40	0	1.00e+00	Cacul1 Retreg2
Retroperitoneal fat weight	806.94	5	3	60	0.97	4.81e-03	Cacul1 Mst1 Retreg2 Uba52 Zfp950l6
Intraocular pressure	10386.52	1	1	20	0	1.00e+00	Retreg2
Extensor digitorum longus weight	271.73	4	1	20	1	4.75e-03	Cacul1 LOC100360095 Mst1 Retreg2
Soleus weight	7.6	4	1	20	0.83	1.70e-01	Cacul1 LOC100360095 Mst1 Retreg2
Tibialis anterior weight	580.28	2	1	20	0	1.00e+00	Mst1 Retreg2
Tibia length	270.96	3	3	60	0	1.00e+00	Mst1 Retreg2 Zfp950l6
Number of licking bursts	67424.86	1	1	20	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	17761.06	2	1	20	0	1.00e+00	Mst1 Retreg2
Times rat made contact with spout	71.66	1	1	20	0	1.00e+00	Retreg2
Mean time between licks in bursts	111630.35	1	1	20	0	1.00e+00	Retreg2
Mean num. licks in bursts	56750.08	1	1	20	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	14881.26	2	1	20	0	1.00e+00	Mst1 Retreg2
Water consumed over 24 hours	17087.8	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging indifference point 0 sec	13062.91	3	1	20	0	1.00e+00	Cacul1 Mst1 Retreg2
Patch foraging indifference point AUC	25114.54	2	2	40	0	1.00e+00	Mst1 Retreg2
Indifference point function ln k	27906.36	2	2	40	0	1.00e+00	Mst1 Retreg2
Indifference point function log k	27906.36	2	2	40	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 0 sec	13987.53	3	1	20	0	1.00e+00	Cacul1 Mst1 Retreg2
Patch foraging total patch changes 12 sec	790.43	3	2	40	0	1.00e+00	Cacul1 Mst1 Retreg2
Patch foraging total patch changes 18 sec	20236.6	2	2	40	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 24 sec	37424.62	2	2	40	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 6 sec	3896.37	2	1	20	0	1.00e+00	Cacul1 Retreg2
Patch foraging time to switch 0 sec	33247.44	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 0 sec	60426.37	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	35322.91	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 18 sec	16867.27	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 24 sec	523.92	2	1	20	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 6 sec	837.86	1	1	20	0	1.00e+00	Retreg2
Locomotor activity	26.79	1	1	20	0	1.00e+00	Mst1
Locomotor testing distance	13845.45	2	2	40	0	1.00e+00	Mst1 Retreg2
Locomotor testing rearing	31715.18	2	2	40	0	1.00e+00	Mst1 Retreg2
Light reinforcement 1	33157.44	2	1	20	0	1.00e+00	Mst1 Retreg2
Light reinforcement 2	18398.05	2	2	40	0	1.00e+00	Mst1 Retreg2
Reaction time number correct	63471.78	1	1	20	0	1.00e+00	Retreg2
Reaction time mean minus median	59976.97	2	1	20	0	1.00e+00	Mst1 Retreg2
Reaction time mean minus median AUC	41337.12	3	2	40	0	1.00e+00	LOC100360095 Mst1 Retreg2
Reaction time num false alarms	7685.9	2	1	20	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms AUC	11677.98	3	1	20	0	1.00e+00	LOC100360095 Mst1 Retreg2
Reaction time trials correct on left	63471.78	1	1	20	0	1.00e+00	Retreg2
Reaction time trials on left	60883.54	1	1	20	0	1.00e+00	Retreg2
Reaction time mean	29724.21	1	1	20	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	20	0	1.00e+00	Retreg2
Median of all reaction times	3949.38	2	1	20	0	1.00e+00	Cacul1 Retreg2
Reaction time omissions	4184.97	2	1	20	0	1.00e+00	Mst1 Retreg2
Reaction time false alarm rate	76.2	3	1	20	0	1.00e+00	LOC100360095 Mst1 Retreg2
Reaction time premature initiation rate	9733.76	1	1	20	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	20	0	1.00e+00	Retreg2
Std. dev. reaction times	30437.76	2	1	20	0	1.00e+00	Mst1 Retreg2
Reaction time trials completed	60883.54	1	1	20	0	1.00e+00	Retreg2
Reaction time trials AUC	62130.65	1	1	20	0	1.00e+00	Retreg2
Social response proportion	4397.95	2	1	20	0	1.00e+00	Mst1 Retreg2
Social responses	640.25	2	1	20	0	1.00e+00	Mst1 Retreg2
Social time	5828.31	2	1	20	0	1.00e+00	Mst1 Retreg2
Conditioned locomotion	1400.08	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	20	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	20	0	1.00e+00	Retreg2
Saline control response	1639.18	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	7271.32	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	28713.86	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	1165.18	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	5466.41	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	1963.38	2	2	40	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever reinforcers received	243.91	2	1	20	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	1278.33	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry latency	6738.25	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	39811.91	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. index score	6407.33	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	8109.24	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	2689.72	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	2097.69	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	17558.57	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	5938.34	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	641.31	2	2	40	0	1.00e+00	Mst1 Retreg2
Conditioned reinforcement - actives	100795.1	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - inactives	32505.31	2	2	40	0	1.00e+00	Mst1 Retreg2
Conditioned locomotion	5172.85	2	1	20	0	1.00e+00	Mst1 Retreg2
Intermittent access intake day 1-15 change	63945.95	2	2	40	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation	63041.23	2	2	40	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	18091.79	2	1	20	0	1.00e+00	Mst1 Retreg2
Intermitt. access day 1 inactive lever presses	90342.67	2	2	40	0	1.00e+00	Mst1 Retreg2
Intermitt. access day 15 inactive lever presses	123608.2	1	1	20	0	1.00e+00	Retreg2
Intermitt. access escalation Index	46701.01	2	2	40	0	1.00e+00	Mst1 Retreg2
Intermittent access day 1 total infusions	33063.01	2	1	20	0	1.00e+00	Mst1 Retreg2
Intermittent access day 15 total infusions	48731.91	1	1	20	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	20	0	1.00e+00	Retreg2
Intermittent access total infusions	181.04	1	1	20	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	34964.22	1	1	20	0	1.00e+00	Retreg2
Intermittent access day 15 total locomotion	85548.8	1	1	20	0	1.00e+00	Retreg2
Intermittent access total locomotion	62.99	2	1	20	0	1.00e+00	Mst1 Retreg2
Intermittent access standard deviation	56995.61	2	2	40	0	1.00e+00	Mst1 Retreg2
Cocaine induced anxiety	69097.7	1	1	20	0	1.00e+00	Retreg2
Post-drug Anxiety	2380.44	2	1	20	0	1.00e+00	Mst1 Retreg2
Baseline Anxiety	33506.24	1	1	20	0	1.00e+00	Retreg2
Lifetime Intake	1655.49	1	1	20	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	71347.91	1	1	20	0	1.00e+00	Retreg2
Incentive Sensitization - Breakpoint	55273.76	1	1	20	0	1.00e+00	Retreg2
Progressive ratio test 1 active lever presses	31979.35	1	1	20	0	1.00e+00	Retreg2
Progressive ratio test 1 breakpoint	30292.17	1	1	20	0	1.00e+00	Retreg2
Progressive ratio test 1 inactive lever presses	31120.43	2	2	40	0	1.00e+00	Mst1 Retreg2
Progressive ratio test 2 active lever presses	15263.76	1	1	20	0	1.00e+00	Retreg2
Progressive ratio test 2 breakpoint	8542.35	1	1	20	0	1.00e+00	Retreg2
Progressive ratio test 2 inactive lever presses	36254.92	2	1	20	0	1.00e+00	Mst1 Retreg2
Total sessions with >9 infusions	1005.82	2	2	40	0	1.00e+00	Mst1 Retreg2
Short access day 1 total inactive lever presses	19749.92	2	2	40	0	1.00e+00	Mst1 Retreg2
Short access day 10 total inactive lever presses	69453.48	2	2	40	0	1.00e+00	Mst1 Retreg2
Short access day 1 total infusions	19198	2	1	20	0	1.00e+00	Mst1 Retreg2
Short access day 10 total infusions	11366.61	2	2	40	0	1.00e+00	Mst1 Retreg2
Short access total infusions	8778.92	1	1	20	0	1.00e+00	Retreg2
Short access day 1 locomotion	12404.88	2	1	20	0	1.00e+00	Mst1 Retreg2
Short access day 10 total locomotion	44094.34	2	1	20	0	1.00e+00	Mst1 Retreg2
Short access total locomotion	9355.68	2	2	40	0	1.00e+00	Mst1 Retreg2
Compulsive drug intake	9345.9	2	1	20	0	1.00e+00	Mst1 Retreg2
One hour access (0.3 mA shock)	2329.1	1	1	20	0	1.00e+00	Retreg2
One hour access (shock baseline)	54988.81	1	1	20	0	1.00e+00	Retreg2
Number of responses in last shaping day	6812.98	2	1	20	0	1.00e+00	Mst1 Retreg2
Context. condit. distance diff. score	212.47	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 1	3523.61	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 1	1024.77	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 2	1110.36	2	2	40	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	258.11	2	1	20	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 3	507.49	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	691.91	2	1	20	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving duration, day 3	1446.08	2	1	20	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	210.64	2	2	40	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	507.07	2	2	40	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving bouts, day 7	2509.72	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	2115.93	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 8	409.23	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization distance	1889.61	2	2	40	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	1027.5	2	1	20	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	957.65	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	1567.62	3	1	20	0	1.00e+00	Cacul1 Mst1 Retreg2
Incentive salience index mean	1780.77	2	1	20	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	2666.81	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in familiar zone, hab. session 1	5593.23	2	1	20	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 1	4629.95	2	2	40	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	429.72	1	1	20	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	20	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	2966.16	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	3208.33	2	2	40	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	38.53	2	1	20	0	1.00e+00	Mst1 Retreg2
Total locomotion distance, hab. session 2	14.23	2	1	20	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	20	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	7678.6	2	1	20	0	1.00e+00	Mst1 Retreg2
Novelty place preference	7474.7	2	1	20	0	1.00e+00	Mst1 Retreg2
Time in novel zone, NPP test	5350.34	2	1	20	0	1.00e+00	Mst1 Retreg2
Total zone transitions, NPP test	1935.62	1	1	20	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	1687.31	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	276.98	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	522.83	2	1	20	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. index score	214.07	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	224.45	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	372.95	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	250.94	2	1	20	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	82.71	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	223.77	2	2	40	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	303.26	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: apparent density	2733.98	2	1	20	0	1.00e+00	Cacul1 Retreg2
Bone surface	2074.41	3	2	40	0	1.00e+00	Cacul1 Mst1 Retreg2
Bone volume	2161.87	4	1	20	0.99	5.36e-03	Cacul1 Mst1 Retreg2 Uba52
Bone: connectivity density	838.02	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: cortical apparent density	4011.83	3	1	20	0	1.00e+00	Cacul1 Retreg2 Zfp950l6
Bone: cortical porosity	220.21	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: cortical porosity	1113.18	1	1	20	0	1.00e+00	Retreg2
Bone: cortical thickness	86.07	6	2	40	-0.7	1.24e-01	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: cortical thickness	749.09	4	2	40	-0.95	5.14e-02	Cacul1 LOC100360095 Mst1 Retreg2
Bone: cortical tissue density	4340.02	3	1	20	0	1.00e+00	Cacul1 Retreg2 Zfp950l6
Bone: elastic displacement	7604.03	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	83.02	5	2	40	-0.86	6.30e-02	LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: endosteal estimation	4459.49	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: endosteal perimeter	5936.33	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: final force	288.77	6	3	60	1	2.96e-05	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: final moment	57.65	6	3	60	0.9	1.41e-02	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: marrow area	4718.94	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: maximum diameter	1231.25	5	2	40	1	1.40e-04	Cacul1 Mst1 Retreg2 Uba52 Zfp950l6
Bone: maximum force	1473.16	6	3	60	1	5.81e-06	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: maximum moment	1021.01	6	3	60	1	9.41e-07	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: minimum diameter	692.27	6	2	40	1	1.35e-05	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: periosteal estimation	1645.58	6	2	40	1	3.13e-05	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: periosteal perimeter	1913.53	6	2	40	0.99	4.07e-05	Cacul1 LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: post-yield work	6843.13	2	1	20	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	1826.64	5	2	40	1	1.40e-04	LOC100360095 Mst1 Retreg2 Uba52 Zfp950l6
Bone: tissue strength	1502.26	2	1	20	0	1.00e+00	Retreg2 Zfp950l6
Bone: trabecular number	5372.17	2	1	20	0	1.00e+00	Retreg2 Uba52
Bone: trabecular spacing	3991.76	2	2	40	0	1.00e+00	Mst1 Retreg2
Bone: trabecular thickness	1708.92	5	2	40	1	1.19e-04	Cacul1 LOC100360095 Mst1 Retreg2 Uba52
Bone: trabecular tissue density	7288.79	2	2	40	0	1.00e+00	Mst1 Retreg2
Breakpoint value in progressive ratio session	18809.48	2	1	20	0	1.00e+00	Mst1 Retreg2
Distance traveled before self-admin	50534.09	1	1	20	0	1.00e+00	Retreg2
Distance traveled after self-admin	32464.08	1	1	20	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	126.71	2	1	20	0	1.00e+00	Mst1 Retreg2
Delta time in open arm before/after self-admin	7570.03	2	1	20	0	1.00e+00	Mst1 Retreg2
Diff in mean of infusions in LGA sessions	18336.8	2	2	40	0	1.00e+00	Mst1 Retreg2
Extinction: sum of active levers before priming	14221.72	2	2	40	0	1.00e+00	Mst1 Retreg2
Active lever presses in extinction session 6	384.74	2	2	40	0	1.00e+00	Mst1 Retreg2
Delta distance traveled before/after self-admin	2940.47	1	1	20	0	1.00e+00	Retreg2
Delta ambulatory time before/after self-admin	30849.75	1	1	20	0	1.00e+00	Retreg2
Time in closed arm before self-admin	13457.43	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in closed arm after self-admin	2326.29	2	2	40	0	1.00e+00	Mst1 Retreg2
Time in open arm before self-admin	4379.48	2	1	20	0	1.00e+00	Mst1 Retreg2
Time in open arm after self-admin	277.78	2	2	40	0	1.00e+00	Mst1 Retreg2
Sum of active levers in priming session hrs 5-6	978.69	1	1	20	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	6696.83	2	2	40	0	1.00e+00	Mst1 Retreg2
Time to tail flick, vehicle, after self-admin	42142.71	1	1	20	0	1.00e+00	Retreg2
Time to tail flick, test, before self-admin	4073.42	2	1	20	0	1.00e+00	Mst1 Retreg2
Time to tail flick, test, after self-admin	1399.18	1	1	20	0	1.00e+00	Retreg2
Delta time to tail flick, vehicle, before/after SA	4924	2	2	40	0	1.00e+00	Mst1 Retreg2
Delta time to tail flick, test, before/after SA	7847.8	2	1	20	0	1.00e+00	Mst1 Retreg2
Ambulatory time before self-admin	39439.86	2	1	20	0	1.00e+00	Retreg2 Uba52
Ambulatory time after self-admin	8877.15	3	1	20	0	1.00e+00	Mst1 Retreg2 Uba52
Total heroin consumption	240.55	1	1	20	0	1.00e+00	Retreg2
Area under the delay curve	24791.27	1	1	20	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	20	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	21959.9	1	1	20	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	20	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	20	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	311.73	2	1	20	0	1.00e+00	Mst1 Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	16922.54	1	1	20	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	20	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	20	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	5669.94	1	1	20	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 1	13009.3	1	1	20	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	20	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	20	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	22349.64	1	1	20	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	68821.85	1	1	20	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	20	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	20	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	82029.05	1	1	20	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	99042.67	1	1	20	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	25503.09	1	1	20	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	8477.87	1	1	20	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	20	0	1.00e+00	Retreg2
Weight adjusted by age	23597.68	3	1	20	0	1.00e+00	Cacul1 Retreg2 Zfp950l6
Seeking ratio, delayed vs. immediate footshock	6725.94	2	1	20	0	1.00e+00	Cacul1 Retreg2
Locomotion in novel chamber	3903.37	1	1	20	0	1.00e+00	Retreg2
Locomotion in novel chamber post-restriction	65422.89	1	1	20	0	1.00e+00	Retreg2
Progressive ratio	33946.79	2	1	20	0	1.00e+00	Cacul1 Retreg2
Food seeking constrained by brief footshock	941.37	2	1	20	0	1.00e+00	Cacul1 Retreg2
Seeking ratio, punishment vs. effort	41283.25	1	1	20	0	1.00e+00	Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	20	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	7664.74	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	7166.92	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	1716.51	1	1	20	0	1.00e+00	Retreg2
Co content in liver	571.82	2	1	20	0	1.00e+00	LOC100360095 Retreg2
Cu content in liver	39.92	1	1	20	0	1.00e+00	Retreg2
Fe content in liver	1344.53	1	1	20	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	1009.39	1	1	20	0	1.00e+00	Retreg2
Na content in liver	4018.36	1	1	20	0	1.00e+00	Retreg2
Rb content in liver	87.87	1	1	20	0	1.00e+00	Retreg2
Zn content in liver	3745.55	1	1	20	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.51
Adipose	alternative TSS	0	0	1.58
Adipose	gene expression	0	0	1.51
Adipose	isoform ratio	0	0	1.54
Adipose	intron excision ratio	0	0	1.51
Adipose	mRNA stability	0	0	1.5
BLA	alternative polyA	0	0	1.54
BLA	alternative TSS	0	0	1.44
BLA	gene expression	0	0	1.55
BLA	isoform ratio	0	0	1.58
BLA	intron excision ratio	0	0	1.44
BLA	mRNA stability	0	0	1.48
Brain	alternative polyA	0	0	1.54
Brain	alternative TSS	0	0	1.53
Brain	gene expression	1	0	1.53
Brain	isoform ratio	0	0	1.55
Brain	intron excision ratio	0	0	1.47
Brain	mRNA stability	0	0	1.5
Eye	alternative polyA	0	0	1.88
Eye	alternative TSS	0	0	1.58
Eye	gene expression	0	0	1.53
Eye	isoform ratio	0	0	1.87
Eye	intron excision ratio	0	0	1.28
Eye	mRNA stability	0	0	1.42
IC	alternative polyA	0	0	1.6
IC	alternative TSS	0	0	1.55
IC	gene expression	0	0	1.56
IC	isoform ratio	0	0	1.63
IC	intron excision ratio	0	0	1.52
IC	mRNA stability	0	0	1.43
IL	alternative polyA	0	0	1.54
IL	alternative TSS	0	0	1.52
IL	gene expression	0	0	1.56
IL	isoform ratio	0	0	1.66
IL	intron excision ratio	0	0	1.48
IL	mRNA stability	0	0	1.59
LHb	alternative polyA	0	0	1.47
LHb	alternative TSS	0	0	1.46
LHb	gene expression	0	0	1.56
LHb	isoform ratio	0	0	1.53
LHb	intron excision ratio	0	0	1.29
LHb	mRNA stability	0	0	1.52
Liver	alternative polyA	0	0	1.61
Liver	alternative TSS	0	0	1.52
Liver	gene expression	1	0	1.53
Liver	isoform ratio	2	0.1	1.59
Liver	intron excision ratio	0	0	1.43
Liver	mRNA stability	0	0	1.48
NAcc	alternative polyA	1	0	3.48
NAcc	alternative TSS	0	0	1.54
NAcc	gene expression	0	0	1.54
NAcc	isoform ratio	0	0	1.54
NAcc	intron excision ratio	0	0	1.51
NAcc	mRNA stability	0	0	1.48
OFC	alternative polyA	0	0	1.71
OFC	alternative TSS	0	0	1.58
OFC	gene expression	0	0	1.56
OFC	isoform ratio	0	0	1.56
OFC	intron excision ratio	0	0	1.39
OFC	mRNA stability	0	0	1.54
PL	alternative polyA	0	0	1.52
PL	alternative TSS	0	0	1.58
PL	gene expression	0	0	1.57
PL	isoform ratio	1	0	1.55
PL	intron excision ratio	0	0	1.48
PL	mRNA stability	0	0	1.48
pVTA	alternative polyA	0	0	1.53
pVTA	alternative TSS	0	0	1.62
pVTA	gene expression	0	0	1.56
pVTA	isoform ratio	0	0	1.6
pVTA	intron excision ratio	0	0	1.48
pVTA	mRNA stability	0	0	1.51
RMTg	alternative polyA	0	0	1.3
RMTg	alternative TSS	0	0	1.58
RMTg	gene expression	0	0	1.55
RMTg	isoform ratio	0	0	1.47
RMTg	intron excision ratio	0	0	1.34
RMTg	mRNA stability	0	0	1.43