Hub : Genes

Amz2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Amz2 0.07 0.05 4.0e-04 0.01 0.01 0.01 0 3.2e-02 3.5e-02 3.0e-02 1.4e-01
2 PL gene expression Amz2 0.31 0.15 0.0e+00 0.22 0.19 0.2 0.2 1.3e-23 1.1e-20 4.2e-21 2.6e-21
3 LHb gene expression Amz2 0.17 0.09 1.7e-03 0.13 0.09 0.09 0.11 6.0e-04 4.5e-03 3.3e-03 1.4e-03
4 OFC gene expression Amz2 0.16 0.09 2.7e-03 0.12 0.15 0.12 0.16 1.1e-03 2.2e-04 8.1e-04 1.4e-04
5 NAcc gene expression Amz2 0.14 0.06 5.6e-17 0.16 0.16 0.16 0.16 9.0e-18 3.9e-18 1.8e-18 2.4e-18
6 IL gene expression Amz2 0.23 0.11 2.8e-04 0.09 0.11 0.03 0.08 4.7e-03 1.7e-03 6.3e-02 7.2e-03
7 BLA gene expression Amz2 0.26 0.09 5.6e-17 0.29 0.28 0.28 0.29 5.7e-16 3.1e-15 2.2e-15 6.5e-16
8 pVTA gene expression Amz2 0.12 0.08 2.9e-03 0.07 0.04 0.01 0.03 5.5e-04 1.0e-02 1.4e-01 1.4e-02
9 Brain gene expression Amz2 0.18 0.07 0.0e+00 0.16 0.19 0.18 0.15 4.6e-15 8.7e-18 6.0e-17 3.2e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density4.06.78.6-0.82.82.9-2.92.8-2.82.72.5-2.5
Area under the delay curve0.20.21.11.0-0.3-0.10.1-0.30.2-0.5-0.10.7
BMI with tail6.621.427.01.1-4.9-4.95.0-4.94.9-4.9-5.24.4
BMI without tail5.411.115.91.0-3.5-3.73.8-3.62.9-3.5-4.02.9
Body weight7.431.237.52.7-5.8-5.85.8-5.85.7-5.9-6.15.8
Weight adjusted by age5.25.88.50.9-2.5-2.62.6-2.52.9-2.3-2.42.5
Bone surface3.35.98.50.42.72.8-2.82.7-2.92.52.1-1.7
Bone volume2.34.06.50.62.22.3-2.32.2-2.62.01.6-1.2
Breakpoint value in progressive ratio session0.60.71.2-0.9-0.8-0.70.8-0.81.1-1.1-0.60.5
Number of licking bursts0.20.20.60.7-0.5-0.10.2-0.30.6-0.5-0.40.8
Context. condit. distance diff. score0.10.10.30.2-0.3-0.20.2-0.30.4-0.3-0.30.6
Locomotion velocity, session 10.00.00.1-0.3-0.3-0.00.0-0.1-0.0-0.3-0.00.0
Locomotion distance, session 10.10.10.7-0.8-0.4-0.10.1-0.2-0.1-0.2-0.00.0
Locomotion velocity, session 20.50.61.4-1.20.40.5-0.60.5-1.00.40.7-1.0
Locomotion distance, session 20.50.74.3-2.10.10.3-0.30.3-0.80.20.6-0.9
Locomotion velocity, session 31.21.46.2-2.5-1.0-0.90.9-1.00.8-1.1-0.60.2
Locomotion distance, session 30.20.21.1-1.10.20.5-0.50.3-0.20.20.4-0.0
Stereotopy head waving bouts, day 31.51.87.0-2.60.80.7-0.70.8-0.90.81.5-1.8
Stereotopy head waving duration, day 31.01.24.9-2.20.70.6-0.60.7-0.80.61.1-1.3
Locomotion velocity, session 70.30.30.5-0.70.50.7-0.60.5-0.50.50.4-0.5
Locomotion distance, session 70.20.30.40.40.60.6-0.60.5-0.60.60.1-0.0
Stereotopy head waving bouts, day 71.21.46.6-2.60.70.7-0.70.8-0.50.61.1-1.5
Stereotopy head waving duration, day 72.32.89.2-3.01.21.3-1.31.3-0.91.21.7-2.1
Locomotion velocity, session 80.00.00.20.4-0.2-0.20.1-0.2-0.0-0.1-0.10.3
Locomotion distance, session 80.10.10.8-0.9-0.3-0.10.0-0.2-0.4-0.1-0.0-0.1
Degree of sensitization distance0.30.32.01.40.2-0.0-0.00.1-0.50.2-0.3-0.0
Degree of sensitization stereotypy0.60.74.6-2.10.20.3-0.30.3-0.10.10.5-0.9
Conditioned locomotion0.30.40.80.30.50.7-0.70.6-0.90.40.5-0.7
Cocaine response after cond. corrected0.30.32.41.50.30.4-0.40.4-0.30.3-0.00.2
Cocaine response after cond. not corrected0.40.42.51.60.40.5-0.50.4-0.30.40.00.2
Cocaine response before conditioning0.10.10.5-0.70.10.1-0.20.1-0.20.20.3-0.2
Saline control response4.15.47.3-0.6-2.5-2.52.5-2.62.4-2.7-2.22.0
Bone: connectivity density7.111.112.7-2.03.53.6-3.53.5-3.53.43.3-3.5
Bone: cortical apparent density0.50.61.4-1.2-0.9-0.90.8-0.80.7-0.8-0.2-0.2
Bone: cortical area0.61.01.7-0.4-1.2-0.90.9-1.10.2-1.3-1.21.0
Bone: cortical porosity0.10.10.50.70.20.1-0.10.1-0.6-0.0-0.30.2
Bone: cortical porosity0.40.40.90.8-0.4-0.50.5-0.50.1-0.6-1.00.9
Bone: cortical thickness3.66.08.4-2.9-2.9-2.52.5-2.72.2-2.8-1.81.1
Bone: cortical thickness0.80.96.6-2.6-0.5-0.20.2-0.30.0-0.40.2-0.8
Bone: cortical tissue density0.40.61.3-1.2-0.9-0.80.8-0.80.7-0.8-0.1-0.2
Condit. Reinf. active minus inactive responses1.21.33.01.7-1.1-1.01.0-1.10.4-1.1-1.21.4
Condit. Reinf. active-inactive response ratio0.20.21.61.30.00.0-0.0-0.0-0.0-0.1-0.10.4
Condit. Reinf. active responses0.60.71.31.1-0.8-0.80.8-0.8-0.0-0.7-1.01.0
Condit. Reinf. inactive responses0.10.10.3-0.5-0.1-0.10.1-0.1-0.50.0-0.3-0.0
Incentive salience index mean0.40.50.60.6-0.7-0.80.7-0.80.3-0.6-0.70.7
Condit. Reinf. lever presses0.40.50.8-0.9-0.7-0.80.8-0.80.7-0.5-0.50.4
Condit. Reinf. active minus inactive responses0.40.62.00.80.60.8-0.80.7-1.40.60.2-0.1
Condit. Reinf. active-inactive response ratio0.80.91.91.40.91.0-1.00.9-1.20.80.4-0.1
Condit. Reinf. active responses0.30.52.20.80.50.6-0.60.5-1.50.5-0.10.1
Condit. Reinf. inactive responses0.10.20.9-1.0-0.2-0.20.2-0.2-0.7-0.2-0.3-0.0
Condit. Reinf. lever presses0.20.30.80.1-0.6-0.60.6-0.6-0.1-0.6-0.90.6
Condit. Reinf. lever reinforcers received0.30.41.61.10.30.5-0.50.4-1.30.3-0.20.2
Conditioned reinforcement - actives3.63.64.9-1.31.91.8-1.81.9-2.02.12.1-2.2
Conditioned reinforcement - inactives0.00.00.0-0.1-0.1-0.10.1-0.0-0.10.1-0.10.1
Conditioned locomotion0.20.31.51.20.30.2-0.20.2-0.60.3-0.00.3
Patch foraging indifference point 0 sec3.04.87.00.9-2.5-2.42.4-2.41.2-2.3-2.62.2
Patch foraging indifference point AUC0.81.02.21.5-0.9-0.70.7-0.90.6-1.3-0.61.2
Delay disc. indifference point, 0s delay0.10.10.70.80.30.3-0.30.30.10.30.30.1
Delay disc. indifference point, 16s delay1.21.22.21.5-1.0-1.01.0-1.01.0-1.1-1.01.3
Delay disc. indifference point, 2s delay0.10.10.91.00.10.3-0.30.1-0.2-0.10.20.3
Delay disc. indifference point, 24s delay0.10.10.40.6-0.2-0.10.1-0.2-0.1-0.4-0.30.5
Delay disc. indifference point, 4s delay0.10.11.11.0-0.10.1-0.1-0.00.0-0.30.10.3
Delay disc. indifference point, 8s delay0.20.20.70.0-0.5-0.20.2-0.50.7-0.80.00.5
Indifference point function ln k1.82.58.0-2.81.31.2-1.21.3-1.61.41.2-1.7
Indifference point function log k1.82.58.0-2.81.31.2-1.21.3-1.61.41.2-1.7
Patch foraging total patch changes 0 sec3.04.86.90.9-2.5-2.52.5-2.41.2-2.3-2.62.1
Patch foraging total patch changes 12 sec1.82.45.12.3-1.6-1.31.2-1.50.6-1.7-1.51.7
Patch foraging total patch changes 18 sec4.15.27.50.9-2.6-2.42.4-2.61.8-2.7-2.32.3
Patch foraging total patch changes 24 sec1.51.92.71.1-1.4-1.41.3-1.50.4-1.6-1.51.5
Patch foraging total patch changes 6 sec5.37.910.52.9-2.9-2.62.6-2.81.9-3.1-3.03.2
Patch foraging time to switch 0 sec0.10.21.31.1-0.1-0.10.1-0.10.60.0-0.30.4
Patch foraging water rate 0 sec0.71.11.80.5-1.2-1.21.1-1.20.3-1.3-1.00.9
Patch foraging water rate 12 sec1.01.52.2-0.5-1.5-1.21.2-1.41.2-1.5-1.31.0
Patch foraging water rate 18 sec0.50.73.3-1.80.40.5-0.50.5-0.80.50.4-1.1
Patch foraging water rate 24 sec0.70.92.2-1.50.70.9-0.90.8-1.00.70.7-1.2
Patch foraging water rate 6 sec0.10.11.0-1.0-0.2-0.00.0-0.1-0.1-0.40.1-0.4
Seeking ratio, delayed vs. immediate footshock2.83.24.50.7-1.7-1.91.9-1.91.9-1.8-1.92.1
Distance traveled before self-admin0.30.40.90.9-0.5-0.40.4-0.50.6-0.5-0.50.7
Distance traveled after self-admin0.40.50.90.9-0.7-0.50.5-0.60.6-0.6-0.70.8
Extensor digitorum longus weight1.55.713.50.6-2.4-2.12.1-2.33.7-2.5-2.02.7
Bone: elastic displacement0.60.64.7-2.2-0.00.2-0.20.1-0.2-0.00.4-0.8
Bone: elastic work0.20.31.7-1.3-0.5-0.20.3-0.40.4-0.6-0.3-0.1
Bone: endosteal estimation1.83.823.34.81.11.3-1.21.2-1.71.0-0.21.2
Bone: endosteal perimeter1.73.518.44.31.31.4-1.31.3-2.01.1-0.11.1
Epididymis fat weight8.720.228.23.4-4.4-4.34.4-4.55.3-4.7-4.64.6
Delta time in closed arm before/after self-admin2.92.83.9-0.01.91.7-1.71.8-1.82.01.7-1.5
Delta time in open arm before/after self-admin1.31.35.1-2.30.80.8-0.80.9-0.80.81.0-1.2
Diff in mean of infusions in LGA sessions1.31.42.30.4-1.2-1.21.2-1.31.5-1.4-1.01.1
Delay discount exponential model param0.30.31.9-1.40.20.1-0.10.2-0.10.50.2-0.7
Extinction: sum of active levers before priming0.20.20.50.7-0.3-0.30.3-0.40.4-0.5-0.40.5
Active lever presses in extinction session 60.10.10.20.2-0.4-0.50.5-0.40.3-0.4-0.30.2
Bone: final force0.10.10.30.10.10.4-0.40.2-0.5-0.00.10.2
Bone: final moment0.10.10.5-0.00.20.5-0.50.3-0.70.00.20.0
Food consumed during 24 hour testing period3.64.46.1-0.5-2.5-2.32.3-2.42.2-2.3-2.11.5
Glucose0.10.10.4-0.0-0.1-0.00.1-0.10.5-0.1-0.30.7
Heart weight1.21.73.31.0-1.2-1.21.2-1.20.9-1.2-1.71.8
Delay discount hyperbolic model param0.30.31.7-1.30.30.1-0.10.3-0.20.60.2-0.7
Intermittent access intake day 1-15 change0.60.63.81.9-0.3-0.40.4-0.40.3-0.3-0.40.7
Intermittent access intake escalation0.50.53.61.9-0.1-0.20.2-0.20.2-0.2-0.30.6
Intermittent access intake escalation 20.60.64.72.20.30.3-0.30.2-0.30.10.00.3
Intermitt. access day 1 inactive lever presses0.20.20.5-0.0-0.4-0.40.4-0.40.1-0.4-0.70.4
Intermitt. access day 15 inactive lever presses0.80.81.10.8-1.0-1.01.0-0.91.1-0.8-0.90.8
Intermitt. access escalation Index0.50.40.50.60.60.7-0.70.6-0.70.50.6-0.7
Intermittent access day 1 total infusions0.20.21.7-1.3-0.1-0.20.2-0.1-0.30.10.0-0.4
Intermittent access day 15 total infusions0.20.21.11.1-0.3-0.40.4-0.3-0.0-0.1-0.30.3
Intermittent access terminal intake (last 3 days)0.20.21.21.10.10.0-0.00.1-0.40.20.10.0
Intermittent access total infusions0.00.00.1-0.3-0.1-0.10.1-0.1-0.30.1-0.0-0.2
Intermittent access day 1 locomotion0.50.50.80.3-0.8-0.90.9-0.80.4-0.5-0.90.7
Intermittent access day 15 total locomotion0.10.10.90.90.0-0.00.00.1-0.50.2-0.10.2
Intermittent access total locomotion1.01.21.70.8-1.2-1.21.2-1.10.5-0.9-1.31.1
Intermittent access standard deviation0.30.31.31.2-0.3-0.40.4-0.40.2-0.5-0.40.8
Left kidney weight0.71.92.6-1.1-1.5-1.51.6-1.51.2-1.3-1.61.1
Right kidney weight0.51.32.80.1-1.1-1.21.2-1.21.1-1.0-1.71.1
Cocaine induced anxiety1.11.31.7-0.61.11.2-1.21.2-1.11.31.3-1.0
Post-drug Anxiety0.50.51.00.40.60.9-0.90.8-0.50.81.0-0.4
Baseline Anxiety0.40.50.90.1-0.8-0.70.7-0.70.9-0.8-0.60.5
Tail length0.61.73.31.8-1.1-1.21.2-1.20.9-1.2-1.41.4
Length with tail1.24.56.82.2-2.0-1.91.9-2.12.1-2.2-2.02.6
Length without tail0.30.72.10.6-0.7-0.50.5-0.61.4-0.8-0.41.1
Times rat made contact with spout0.60.71.10.7-1.0-0.80.8-0.90.8-0.9-1.10.7
Lifetime Intake0.10.10.9-0.9-0.1-0.10.1-0.1-0.40.1-0.0-0.3
Liver weight, left0.50.81.1-0.60.81.0-1.00.8-1.00.61.0-1.0
Liver weight, right0.10.20.8-0.9-0.3-0.10.1-0.20.3-0.40.1-0.5
Locomotor activity0.71.11.8-0.6-1.3-1.21.2-1.20.6-1.3-1.10.8
Locomotor testing distance0.81.32.3-0.7-1.5-1.21.2-1.30.6-1.4-1.00.9
Locomotor testing rearing2.23.55.70.3-2.3-1.91.9-2.11.6-2.4-1.71.7
Locomotion in novel chamber0.50.61.10.9-0.7-0.80.8-0.71.0-0.6-0.70.9
Locomotion in novel chamber post-restriction0.00.00.10.0-0.00.0-0.0-0.0-0.10.1-0.0-0.3
Fecal boli incidents, locomotor time 10.50.51.61.30.70.7-0.70.7-0.70.80.4-0.1
Change in fecal boli incidents, locomotor task0.40.41.21.1-0.6-0.30.3-0.60.4-1.0-0.00.5
Time >=10cm from walls, locomotor time 10.50.52.3-1.50.50.3-0.30.4-0.50.60.7-0.8
Bouts of movement, locomotor time 11.11.11.60.4-1.2-1.21.3-1.21.1-1.1-1.00.9
Total resting periods, locomotor time 10.40.40.60.6-0.6-0.70.7-0.70.7-0.6-0.60.6
Rest time, locomotor task time 10.10.10.20.30.40.3-0.30.20.20.00.20.1
Distance moved, locomotor task time 11.01.11.9-0.7-1.4-1.11.1-1.11.2-1.2-0.80.7
Vertical activity count, locomotor time 10.80.81.5-0.1-1.2-1.11.0-1.00.9-1.0-0.70.6
Time >=10cm from walls, locomotor time 22.22.43.7-0.3-1.7-1.81.8-1.71.9-1.7-1.21.0
Bouts of movement, locomotor time 23.84.15.30.0-2.1-2.22.2-2.22.3-2.3-2.01.8
Total resting periods, locomotor time 22.83.04.1-0.1-1.8-1.81.8-1.92.0-2.0-1.71.7
Rest time, locomotor task time 22.42.84.1-0.51.91.9-1.91.8-1.21.82.0-1.4
Distance moved, locomotor task time 22.73.24.4-0.7-2.1-2.02.0-2.02.1-1.9-1.51.0
Vertical activity count, locomotor time 22.62.84.00.2-2.0-2.02.0-1.91.5-1.8-1.71.0
Light reinforcement 10.71.22.8-1.7-1.3-1.11.1-1.20.8-1.3-0.80.3
Light reinforcement 20.10.10.8-0.9-0.1-0.20.2-0.20.4-0.1-0.10.2
Bone: marrow area1.83.823.04.81.11.3-1.31.2-1.71.0-0.11.2
Bone: maximum diameter0.61.12.51.31.01.1-1.11.0-1.60.80.40.2
Bone: maximum force0.10.10.30.5-0.00.2-0.20.1-0.5-0.1-0.30.5
Bone: maximum moment0.10.10.40.40.00.3-0.30.2-0.6-0.1-0.20.4
Mean time between licks in bursts0.81.12.40.9-0.8-0.80.8-0.91.5-0.9-1.21.6
Mean num. licks in bursts0.00.00.1-0.2-0.1-0.30.3-0.2-0.1-0.0-0.2-0.3
Cd content in liver2.42.74.4-0.21.81.8-1.81.8-1.11.72.1-1.6
Co content in liver0.10.10.4-0.10.40.2-0.20.40.20.60.4-0.0
Cu content in liver0.40.40.70.00.70.7-0.70.7-0.80.80.6-0.6
Fe content in liver0.50.50.8-0.90.60.8-0.80.7-0.80.60.8-0.6
K content in liver2.42.43.3-0.51.51.5-1.51.6-1.81.61.5-1.8
Mg content in liver5.25.47.9-0.72.32.3-2.32.4-2.62.42.4-2.8
Mn content in liver5.56.38.1-2.02.52.6-2.52.5-2.72.42.5-2.8
Na content in liver1.21.33.0-1.71.01.1-1.11.1-1.01.01.1-1.0
Rb content in liver0.91.11.8-1.11.01.1-1.11.1-0.71.01.3-1.0
Se content in liver0.40.51.7-1.30.50.5-0.50.5-0.30.60.6-0.8
Sr content in liver1.11.01.50.4-1.0-1.21.2-1.10.8-0.9-1.11.1
Zn content in liver2.32.63.5-1.41.41.4-1.41.5-1.81.91.6-1.8
Bone: minimum diameter1.01.912.33.5-0.20.0-0.0-0.1-0.8-0.2-1.11.6
Time in familiar zone, hab. session 10.60.54.02.00.0-0.10.1-0.0-0.00.1-0.40.8
Time in novel zone, hab. session 10.30.32.4-1.50.00.00.00.0-0.2-0.10.2-0.8
Total zone transitions, hab. session 10.91.31.8-1.0-1.2-1.31.3-1.21.1-1.1-1.20.7
Total locomotion distance, hab. session 11.11.52.2-1.3-1.5-1.41.4-1.30.9-1.3-1.10.6
Locomotion velocity, hab. session 11.01.42.0-1.1-1.4-1.41.4-1.31.0-1.2-1.00.6
Time in familiar zone, hab. session 20.50.52.51.6-0.4-0.20.2-0.40.1-0.4-0.50.9
Time in novel zone, hab. session 21.71.73.3-1.71.21.0-1.01.1-1.01.21.2-1.8
Total zone transitions, hab. session 21.21.62.2-1.3-1.3-1.51.5-1.41.2-1.1-1.20.6
Total locomotion distance, hab. session 21.92.53.6-1.1-1.9-1.81.8-1.81.5-1.7-1.40.8
Locomotion velocity, hab. session 21.52.02.8-1.4-1.7-1.61.6-1.51.3-1.5-1.10.6
Novel to familiar place preference ratio0.50.52.21.5-0.4-0.40.4-0.40.1-0.5-0.71.0
Novelty place preference0.20.21.01.0-0.2-0.30.3-0.20.0-0.3-0.50.8
Time in novel zone, NPP test0.20.20.80.9-0.2-0.20.2-0.2-0.1-0.2-0.40.6
Total zone transitions, NPP test0.60.93.7-1.9-1.1-0.90.8-0.90.2-0.9-0.3-0.2
Total locomotion distance, NPP test0.60.82.2-1.5-1.1-1.01.0-0.90.2-0.8-0.4-0.4
Locomotion velocity, NPP test1.11.52.6-1.4-1.6-1.51.4-1.40.7-1.3-0.90.2
Intraocular pressure0.71.01.40.5-1.1-1.11.1-1.10.6-1.1-1.21.1
Delta distance traveled before/after self-admin0.20.21.6-1.3-0.3-0.20.2-0.20.1-0.2-0.0-0.5
Delta ambulatory time before/after self-admin0.20.20.4-0.10.30.5-0.50.5-0.60.50.4-0.7
Parametrial fat weight1.12.22.90.71.71.6-1.61.6-1.51.51.7-1.4
Pavlov. Cond. lever latency2.43.14.50.31.82.1-2.11.9-1.81.71.8-1.5
Pavlov. Cond. magazine entry latency0.40.50.70.6-0.5-0.80.8-0.80.5-0.8-0.90.8
Pavlov. Cond. change in total contacts1.31.42.10.1-1.1-1.31.3-1.31.1-1.1-1.41.1
Pavlov. Cond. index score1.11.42.00.2-1.1-1.41.4-1.31.1-1.2-1.41.2
Pavlov. Cond. latency score1.62.02.70.2-1.4-1.61.6-1.51.4-1.4-1.61.4
Pavlov. Cond. lever contacts2.22.63.5-0.2-1.6-1.81.9-1.71.8-1.6-1.71.4
Pavlov. Cond. magazine entry number0.20.20.4-0.30.20.6-0.60.5-0.30.50.6-0.6
Pavlov. Cond. intertrial magazine entries1.11.42.71.2-1.3-1.01.0-1.10.3-1.0-1.51.6
Pavlov. Cond. lever-magazine prob. diff.0.91.11.5-0.1-0.9-1.21.2-1.10.9-1.0-1.21.0
Pavlov. Cond. response bias0.40.50.9-0.3-0.5-0.90.9-0.80.6-0.7-0.80.6
Pavlov. Cond. lever latency0.60.82.30.5-0.7-0.90.9-0.81.5-0.8-0.60.8
Pavlov. Cond. magazine entry latency0.00.00.20.3-0.2-0.10.1-0.10.1-0.20.00.4
Pavlov. Cond. change in total contacts0.20.20.80.20.30.6-0.60.4-0.90.30.2-0.2
Pavlov. Cond. index score0.10.20.60.20.20.4-0.50.3-0.80.30.2-0.0
Pavlov. Cond. latency score0.10.10.60.20.20.4-0.40.3-0.80.20.20.0
Pavlov. Cond. lever contacts0.30.41.3-0.70.40.6-0.60.5-1.10.50.4-0.7
Pavlov. Cond. magazine entry number0.10.20.4-0.00.50.3-0.30.4-0.40.50.2-0.6
Pavlov. Cond. intertrial magazine entries0.30.41.00.50.60.4-0.40.6-1.00.80.4-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.20.70.20.30.5-0.50.4-0.80.30.3-0.0
Pavlov. Cond. response bias0.30.41.1-0.20.50.7-0.70.6-1.00.50.5-0.5
Time in closed arm before self-admin1.71.93.0-0.5-1.7-1.71.7-1.61.1-1.3-1.40.7
Time in closed arm after self-admin0.30.30.50.6-0.5-0.70.7-0.60.4-0.3-0.50.3
Time in open arm before self-admin1.21.32.71.7-0.8-0.90.9-0.91.5-0.9-0.91.5
Time in open arm after self-admin0.20.30.80.2-0.4-0.30.3-0.30.8-0.5-0.50.9
Bone: periosteal estimation0.71.48.93.00.20.5-0.50.3-1.30.1-0.61.2
Bone: periosteal perimeter0.50.84.72.20.10.3-0.30.2-0.7-0.1-0.51.3
Bone: post-yield work0.30.42.11.50.40.4-0.40.5-0.50.6-0.10.5
Progressive ratio test 1 active lever presses1.41.52.0-1.1-1.3-1.41.4-1.41.0-1.3-1.20.5
Progressive ratio test 1 breakpoint1.81.82.5-0.9-1.5-1.61.6-1.61.1-1.4-1.40.7
Progressive ratio test 1 inactive lever presses1.31.42.3-0.3-1.5-1.51.5-1.40.6-1.3-1.40.6
Progressive ratio test 2 active lever presses0.00.00.1-0.3-0.10.0-0.0-0.1-0.1-0.20.1-0.1
Progressive ratio test 2 breakpoint0.00.00.0-0.20.00.1-0.1-0.0-0.2-0.10.2-0.2
Progressive ratio test 2 inactive lever presses0.20.20.70.20.30.4-0.40.4-0.80.50.4-0.5
Incentive Sensitization - Responses0.40.40.60.40.70.7-0.80.6-0.60.40.8-0.3
Incentive Sensitization - Breakpoint0.40.40.60.50.70.8-0.80.6-0.60.50.8-0.3
Sum of active levers in priming session hrs 5-60.80.71.20.7-0.9-0.70.7-0.80.9-1.1-0.71.0
Progressive ratio0.20.21.11.10.40.5-0.50.5-0.10.40.20.1
Food seeking constrained by brief footshock0.40.41.2-0.01.00.5-0.50.8-0.61.10.3-0.4
Seeking ratio, punishment vs. effort0.20.21.4-1.2-0.0-0.30.3-0.2-0.10.1-0.1-0.3
Retroperitoneal fat weight4.715.318.32.5-4.0-4.04.0-4.04.3-4.0-4.33.8
Reaction time number correct0.91.31.5-1.21.21.1-1.11.2-1.11.11.2-1.2
Reaction time mean minus median0.20.32.11.40.0-0.10.1-0.00.7-0.0-0.10.2
Reaction time mean minus median AUC0.71.01.60.31.31.0-1.01.1-0.81.10.9-1.0
Reaction time num false alarms0.70.91.50.8-0.9-1.01.0-0.90.1-0.9-1.21.2
Reaction time num false alarms AUC0.40.51.01.0-0.6-0.70.7-0.6-0.3-0.6-1.00.9
Reaction time trials correct on left0.91.31.5-1.21.21.1-1.11.2-1.11.11.2-1.2
Reaction time trials on left1.01.41.7-1.11.31.2-1.21.3-1.21.21.2-1.2
Reaction time mean0.60.81.10.61.10.9-0.91.0-0.61.00.9-0.9
Reaction time mean AUC0.40.60.90.40.90.8-0.80.8-0.50.80.8-0.9
Median of all reaction times0.81.21.60.11.31.1-1.11.2-1.01.11.1-1.2
Reaction time omissions0.60.81.30.51.00.8-0.81.0-0.81.10.6-1.1
Reaction time false alarm rate1.01.52.21.4-1.2-1.21.2-1.20.5-1.1-1.51.4
Reaction time premature initiation rate2.12.84.61.8-1.7-1.51.5-1.61.2-1.8-1.62.1
Reaction time premature initiations0.30.41.00.9-0.6-0.40.4-0.60.2-0.7-0.61.0
Std. dev. reaction times0.60.81.41.21.10.8-0.80.9-0.40.90.8-0.9
Reaction time trials completed1.01.41.7-1.11.31.2-1.21.3-1.21.21.2-1.2
Reaction time trials AUC1.01.41.7-1.01.31.2-1.21.2-1.11.21.2-1.2
Run reversals in cocaine runway, females7.97.612.61.9-2.7-2.82.8-2.83.5-2.7-2.42.9
Run reversals in cocaine runway, males0.20.21.31.10.00.2-0.20.2-0.20.20.1-0.0
Latency to leave start box in cocaine runway2.52.73.7-1.2-1.7-1.91.9-1.81.7-1.8-1.40.9
Latency to leave start box in cocaine runway, F4.14.56.1-0.9-2.0-2.52.4-2.32.3-2.2-2.01.9
Latency to leave start box in cocaine runway, M0.20.20.8-0.9-0.5-0.40.4-0.30.4-0.4-0.1-0.5
Std. dev. time between licks in bursts0.30.31.0-1.0-0.5-0.50.5-0.50.9-0.5-0.20.2
Total sessions with >9 infusions0.40.41.8-1.3-0.6-0.70.7-0.50.2-0.3-0.60.1
Short access day 1 total inactive lever presses0.10.11.0-1.0-0.2-0.20.2-0.10.10.2-0.10.0
Short access day 10 total inactive lever presses0.10.10.30.60.10.2-0.20.2-0.3-0.00.00.1
Short access day 1 total infusions0.70.75.3-2.3-0.5-0.50.5-0.50.1-0.3-0.3-0.2
Short access day 10 total infusions1.31.42.2-0.7-1.3-1.51.5-1.40.8-1.2-1.30.8
Short access total infusions0.40.42.6-1.6-0.4-0.50.5-0.5-0.2-0.2-0.4-0.2
Short access day 1 locomotion0.91.01.4-0.8-1.1-1.21.2-1.10.7-0.8-1.20.6
Short access day 10 total locomotion2.12.43.21.2-1.6-1.71.7-1.61.1-1.3-1.81.6
Short access total locomotion3.23.34.70.2-2.1-2.22.2-2.01.4-1.8-2.21.5
One hour access (0.3 mA shock)0.80.92.2-0.00.91.0-1.00.9-1.51.00.8-0.8
Compulsive drug intake0.70.71.81.40.70.9-0.90.8-1.00.50.5-0.2
One hour access (shock baseline)0.10.20.4-0.60.20.2-0.20.3-0.40.50.3-0.6
Social response proportion0.40.42.61.60.40.4-0.40.4-0.40.40.3-0.1
Social responses0.40.60.80.6-0.9-0.80.8-0.80.2-0.9-0.70.7
Social time0.40.52.71.60.50.5-0.50.5-0.40.60.2-0.0
Soleus weight0.20.61.60.4-0.9-0.50.5-0.61.0-0.6-0.91.3
Bone: stiffness0.10.10.50.7-0.10.0-0.0-0.0-0.2-0.1-0.20.6
Tibialis anterior weight1.13.97.20.9-2.1-1.81.9-2.02.7-2.0-1.92.1
Time to tail flick, vehicle, before self-admin0.40.41.31.20.60.6-0.60.5-0.20.60.60.1
Time to tail flick, vehicle, after self-admin0.91.04.12.00.91.0-1.00.8-0.60.60.70.3
Time to tail flick, test, before self-admin1.61.612.33.5-0.3-0.30.3-0.20.3-0.1-0.61.2
Time to tail flick, test, after self-admin0.50.52.31.50.50.5-0.50.5-1.00.50.2-0.2
Delta time to tail flick, vehicle, before/after SA1.31.32.00.61.31.2-1.21.2-1.41.11.0-0.9
Delta time to tail flick, test, before/after SA1.71.62.8-0.61.31.3-1.31.3-1.71.31.1-1.2
Tibia length1.74.76.41.3-2.3-2.12.1-2.22.4-2.3-2.02.5
Ambulatory time before self-admin0.80.81.30.7-0.8-0.90.9-0.91.1-0.9-0.81.0
Ambulatory time after self-admin0.40.50.70.8-0.8-0.60.6-0.60.7-0.7-0.70.7
Bone: tissue strength0.90.84.5-2.10.40.5-0.50.5-0.50.40.9-0.9
Total heroin consumption0.00.10.10.30.00.3-0.30.2-0.30.10.3-0.1
Bone: trabecular number5.89.010.9-1.43.23.3-3.23.2-3.33.12.9-3.0
Bone: trabecular spacing2.73.54.70.7-2.2-2.02.0-2.02.1-2.0-1.71.8
Bone: trabecular thickness0.60.71.70.80.90.8-0.80.8-1.30.80.4-0.5
Bone: trabecular tissue density1.21.72.30.8-1.4-1.41.4-1.41.3-1.5-1.11.3
Water consumed over 24 hours1.01.21.7-1.3-1.3-1.21.2-1.21.2-1.2-0.90.3
Number of responses in last shaping day2.42.53.50.2-1.9-1.91.9-1.71.7-1.5-1.71.1