Hub : Genes

LOC102551125

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC isoform ratio XR_010063314.1 0.12 0.07 8.2e-04 0.06 0.07 0.07 0.06 1.4e-03 5.1e-04 9.8e-04 1.6e-03
2 Brain isoform ratio XR_010063314.1 0.08 0.05 8.0e-07 0.06 0.07 0.07 0.07 1.0e-06 2.1e-07 2.7e-07 2.1e-07
3 IC gene expression LOC102551125 0.18 0.1 1.3e-07 0.18 0.17 0.16 0.15 6.9e-08 1.8e-07 3.5e-07 6.3e-07
4 BLA isoform ratio XR_010063314.1 0.17 0.09 2.6e-05 0.01 0.07 0.06 0.05 1.2e-01 1.5e-04 4.1e-04 1.6e-03
5 PL isoform ratio XR_010063314.1 0.27 0.17 1.1e-11 0.09 0.11 0.1 0.1 5.2e-10 6.4e-12 9.5e-11 1.8e-11
6 NAcc isoform ratio XR_010063314.1 0.07 0.04 5.0e-07 0.05 0.05 0.04 0.04 1.1e-07 7.8e-08 3.0e-07 2.2e-07
7 PL isoform ratio XR_010063317.1 0.11 0.06 8.3e-08 0.07 0.06 0.05 0.06 4.0e-08 2.6e-07 1.6e-06 7.5e-07
8 OFC intron excision ratio chr1_266581021_266581116 0.31 0.17 7.8e-04 0.08 0.12 0.14 0.1 7.4e-03 7.0e-04 2.9e-04 1.8e-03
9 LHb gene expression LOC102551125 0.53 0.21 6.7e-05 0.08 0.18 0.17 0.1 5.7e-03 4.1e-05 6.7e-05 2.6e-03
10 OFC isoform ratio XR_010063314.1 0.3 0.14 7.4e-05 0.26 0.23 0.21 0.24 6.7e-07 3.5e-06 8.1e-06 1.6e-06
11 IL gene expression LOC102551125 0.6 0.14 7.8e-10 0.31 0.29 0.28 0.28 3.3e-08 1.0e-07 2.5e-07 2.3e-07
12 IL isoform ratio XR_010063314.1 0.21 0.12 1.5e-03 0.16 0.15 0.11 0.14 1.0e-04 2.2e-04 1.6e-03 3.5e-04
13 OFC gene expression LOC102551125 0.37 0.18 3.2e-04 0.16 0.16 0.16 0.08 1.3e-04 1.5e-04 1.3e-04 5.3e-03
14 Adipose isoform ratio XR_010063317.1 0.02 0.02 8.3e-03 0.01 0 0 0 6.4e-02 1.4e-01 1.3e-01 1.5e-01
15 pVTA gene expression LOC102551125 0.05 0.04 2.0e-04 0.04 0.03 0.03 0.04 4.0e-04 8.4e-04 9.8e-04 4.6e-04
16 Adipose gene expression LOC102551125 0.03 0.03 1.4e-03 0.03 0.02 0.03 0.02 5.1e-04 4.5e-03 2.8e-04 3.2e-03
17 Brain gene expression LOC102551125 0.18 0.08 6.1e-15 0.16 0.17 0.16 0.17 8.7e-15 1.1e-15 1.4e-14 2.4e-15
18 Brain isoform ratio XR_010063317.1 0.05 0.03 1.0e-03 0.02 0.03 0.03 0.02 7.1e-03 1.0e-03 1.3e-03 3.4e-03
19 PL gene expression LOC102551125 0.4 0.16 3.2e-14 0.09 0.12 0.12 0.13 1.0e-09 4.1e-13 6.4e-13 7.4e-14
20 IC isoform ratio XR_010063317.1 0.15 0.09 9.7e-05 0.07 0.1 0.14 0.07 5.9e-04 6.1e-05 1.4e-06 7.5e-04
21 NAcc gene expression LOC102551125 0.05 0.03 9.6e-06 0.04 0.03 0.03 0.03 8.8e-07 1.6e-05 1.0e-04 3.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.93.36.51.91.80.81.92.02.02.2-2.0-2.52.2-2.22.2-1.40.7-0.7-0.9-2.01.9-1.92.2-1.5
Area under the delay curve1.01.12.61.51.61.61.40.71.20.6-1.1-1.11.1-1.11.1-1.5-1.01.00.6-0.40.20.01.40.4
BMI with tail3.712.833.35.75.45.85.04.34.02.9-3.8-3.62.8-2.82.8-4.2-3.93.13.0-1.50.9-0.7-0.00.9
BMI without tail2.36.920.94.13.94.63.53.02.61.7-2.8-2.11.7-1.71.7-2.8-3.33.02.9-0.60.10.2-0.81.4
Body weight3.716.039.76.35.95.65.75.24.83.9-3.5-4.73.9-3.93.9-4.0-3.02.52.6-2.62.0-1.60.50.2
Weight adjusted by age2.33.510.72.82.73.32.42.11.60.7-1.8-0.80.3-0.30.3-2.0-2.82.62.50.1-0.50.8-0.71.8
Bone surface0.71.22.71.41.30.61.31.31.31.3-1.0-1.61.3-1.31.3-1.20.3-0.3-0.2-1.11.1-0.91.1-0.5
Bone volume1.42.55.42.32.21.52.22.12.01.9-1.4-2.11.9-1.91.9-1.3-0.20.30.4-1.41.2-1.00.9-0.2
Breakpoint value in progressive ratio session0.60.81.81.31.30.91.31.21.31.1-0.2-1.10.9-0.90.9-0.5-0.10.20.2-0.90.7-0.30.60.6
Number of licking bursts0.71.12.10.70.7-0.00.90.91.11.30.1-1.41.4-1.41.4-0.71.0-0.9-0.8-1.41.4-1.31.2-1.0
Context. condit. distance diff. score0.80.93.2-1.4-1.3-1.5-1.2-1.4-1.0-0.81.80.6-0.70.7-0.71.01.1-0.8-0.50.4-0.30.30.2-0.0
Locomotion velocity, session 10.40.41.2-0.7-0.8-0.5-0.8-0.8-0.8-0.71.10.4-0.60.6-0.60.70.0-0.20.30.5-0.40.5-1.00.2
Locomotion distance, session 10.91.12.4-0.8-1.00.0-1.1-1.3-1.4-1.40.40.8-1.31.3-1.30.5-0.90.40.71.3-1.31.2-1.60.8
Locomotion velocity, session 22.22.54.2-1.6-1.7-0.6-1.9-1.8-2.0-2.00.71.8-1.91.9-1.91.7-0.60.50.91.8-1.61.5-2.10.9
Locomotion distance, session 20.71.02.9-0.2-0.50.5-0.7-1.0-1.1-1.20.00.3-1.11.1-1.1-0.3-1.70.81.41.3-1.31.2-1.21.0
Locomotion velocity, session 31.01.12.0-1.1-1.2-0.9-1.3-1.4-1.4-1.30.91.0-1.31.3-1.30.9-0.00.20.41.2-1.01.0-0.50.6
Locomotion distance, session 31.61.83.4-1.4-1.5-1.0-1.6-1.8-1.7-1.61.41.1-1.71.7-1.71.1-0.20.20.81.5-1.41.3-0.60.8
Stereotopy head waving bouts, day 30.20.33.2-0.0-0.00.00.10.50.10.3-1.80.10.3-0.30.3-0.10.4-0.2-0.6-0.30.5-0.4-0.2-0.6
Stereotopy head waving duration, day 30.50.63.00.30.30.10.50.90.70.7-1.7-0.10.8-0.80.8-0.30.8-0.4-1.0-0.80.9-0.80.4-0.8
Locomotion velocity, session 70.40.52.30.80.91.10.70.40.50.1-0.5-0.10.2-0.20.2-1.5-1.00.90.70.1-0.30.4-0.40.8
Locomotion distance, session 70.20.21.0-0.1-0.00.2-0.1-0.4-0.2-0.40.20.3-0.40.4-0.4-1.0-0.70.60.70.5-0.60.6-0.20.7
Stereotopy head waving bouts, day 70.10.10.40.10.10.40.0-0.0-0.1-0.20.10.2-0.20.2-0.20.2-0.40.50.50.3-0.30.4-0.60.5
Stereotopy head waving duration, day 70.50.61.91.21.21.41.00.90.80.5-0.8-0.50.5-0.50.5-0.5-0.80.80.5-0.20.1-0.0-0.50.3
Locomotion velocity, session 81.31.64.7-1.9-1.9-2.2-1.8-1.7-1.4-0.81.60.3-0.80.8-0.81.11.4-1.7-1.20.20.0-0.20.5-0.9
Locomotion distance, session 81.72.56.0-2.3-2.4-1.9-2.4-2.4-2.2-1.71.71.0-1.61.6-1.61.40.7-1.0-0.41.2-0.90.8-0.1-0.0
Degree of sensitization distance1.01.02.40.91.10.71.21.31.41.2-1.1-0.61.3-1.31.3-1.50.1-0.1-0.7-1.11.0-0.90.5-0.4
Degree of sensitization stereotypy0.10.10.40.40.40.60.40.20.20.0-0.1-0.00.1-0.10.1-0.3-0.50.50.30.1-0.20.2-0.20.4
Conditioned locomotion0.20.31.0-0.3-0.20.1-0.2-0.1-0.3-0.7-0.61.0-0.70.7-0.70.1-0.60.50.20.5-0.60.4-0.70.4
Cocaine response after cond. corrected3.23.86.2-2.1-2.1-1.3-2.3-2.4-2.4-2.51.62.2-2.52.5-2.51.8-0.40.50.82.2-2.12.0-1.31.4
Cocaine response after cond. not corrected2.73.25.0-2.2-2.1-1.4-2.2-2.2-2.2-2.21.02.2-2.22.2-2.21.7-0.10.10.31.9-1.71.6-1.40.8
Cocaine response before conditioning0.81.02.40.10.2-0.20.50.90.81.1-1.6-0.41.1-1.11.1-0.60.9-1.0-1.5-1.21.3-1.30.6-1.4
Saline control response0.91.23.6-0.9-0.8-0.1-0.9-0.7-1.1-1.3-0.61.9-1.31.3-1.30.7-0.81.00.71.3-1.31.3-1.51.1
Bone: connectivity density0.81.25.20.60.5-0.30.70.60.91.1-1.1-1.61.1-1.11.1-1.20.9-1.0-1.1-1.21.2-1.22.3-1.2
Bone: cortical apparent density3.44.67.8-2.2-2.2-1.1-2.5-2.6-2.7-2.81.42.4-2.82.8-2.81.7-0.90.71.12.6-2.42.2-1.41.5
Bone: cortical area3.75.713.23.63.53.33.43.42.82.2-3.5-1.82.2-2.22.2-2.2-1.62.01.4-1.31.0-0.60.10.5
Bone: cortical porosity0.50.51.6-0.4-0.4-0.6-0.20.10.00.4-1.1-0.30.4-0.40.4-0.10.8-1.0-1.3-0.60.7-0.91.0-1.3
Bone: cortical porosity1.21.32.90.20.1-0.40.40.80.71.1-1.6-1.01.1-1.11.1-0.81.1-1.3-1.6-1.31.4-1.51.7-1.7
Bone: cortical thickness1.11.97.52.01.92.21.71.91.30.9-2.7-0.60.9-0.90.9-0.9-1.41.71.2-0.20.10.1-0.40.7
Bone: cortical thickness0.50.62.00.90.91.20.70.70.3-0.0-0.80.2-0.00.0-0.0-0.0-1.01.41.20.4-0.50.7-0.61.1
Bone: cortical tissue density3.54.77.9-2.3-2.4-1.3-2.6-2.8-2.8-2.81.62.3-2.82.8-2.81.8-0.70.51.02.5-2.32.1-1.21.3
Condit. Reinf. active minus inactive responses1.01.13.0-1.4-1.6-1.6-1.4-1.3-1.2-0.50.6-0.3-0.40.4-0.41.21.3-1.7-1.0-0.00.3-0.50.6-1.3
Condit. Reinf. active-inactive response ratio0.60.71.9-0.9-1.1-1.2-0.9-0.7-0.6-0.10.2-0.2-0.10.1-0.11.41.3-1.3-1.0-0.20.5-0.60.6-1.2
Condit. Reinf. active responses0.50.62.5-0.4-0.8-0.8-0.6-0.4-0.50.20.0-1.20.2-0.20.20.80.9-1.6-0.6-0.50.8-1.00.6-1.5
Condit. Reinf. inactive responses0.40.52.40.60.30.00.40.60.40.8-0.3-1.50.8-0.80.8-0.20.2-0.8-0.0-0.81.0-1.00.5-1.0
Incentive salience index mean1.31.64.1-1.7-2.0-1.9-1.9-1.7-1.6-0.91.0-0.1-0.90.9-0.91.51.2-1.7-0.70.4-0.0-0.20.4-1.0
Condit. Reinf. lever presses0.70.92.3-1.2-1.5-1.4-1.4-1.4-1.3-0.81.3-0.2-0.80.8-0.81.10.7-1.2-0.20.4-0.10.00.4-0.5
Condit. Reinf. active minus inactive responses2.73.45.62.01.91.22.12.42.22.3-1.9-2.02.3-2.32.3-2.00.4-0.4-0.7-2.01.9-1.71.4-1.2
Condit. Reinf. active-inactive response ratio1.21.32.51.31.40.81.51.61.51.5-1.0-1.01.5-1.51.5-1.20.3-0.0-0.4-1.21.1-1.00.9-0.5
Condit. Reinf. active responses3.44.87.72.62.52.02.62.72.62.6-2.4-2.52.6-2.62.6-2.8-0.1-0.1-0.4-2.12.0-1.81.4-1.1
Condit. Reinf. inactive responses1.21.53.31.51.41.31.41.41.41.4-1.5-1.61.4-1.41.4-1.8-0.3-0.2-0.2-1.21.1-1.00.5-0.7
Condit. Reinf. lever presses0.91.32.21.51.51.41.51.41.41.3-1.1-1.11.3-1.31.3-1.5-0.30.20.0-1.00.9-0.80.1-0.3
Condit. Reinf. lever reinforcers received2.43.45.42.22.11.72.22.32.22.2-2.1-2.12.2-2.22.2-2.20.0-0.2-0.4-1.91.7-1.61.0-1.0
Conditioned reinforcement - actives0.81.32.6-0.7-0.70.1-0.9-1.0-1.2-1.5-0.21.6-1.41.4-1.40.3-1.01.21.01.6-1.61.3-1.40.8
Conditioned reinforcement - inactives0.20.20.70.70.60.80.50.40.40.1-0.5-0.30.1-0.10.1-0.7-0.80.60.70.0-0.10.2-0.30.2
Conditioned locomotion1.31.73.2-0.9-1.00.0-1.2-1.3-1.5-1.80.41.5-1.71.7-1.70.9-0.91.01.11.7-1.71.5-1.70.9
Patch foraging indifference point 0 sec1.52.77.82.72.62.82.42.11.81.2-0.8-1.31.3-1.31.3-0.8-1.71.72.1-0.50.20.1-1.01.0
Patch foraging indifference point AUC0.60.82.11.31.41.31.41.41.21.0-1.0-0.21.0-1.01.00.0-0.41.00.3-0.50.4-0.1-0.10.4
Delay disc. indifference point, 0s delay0.40.51.60.70.81.30.60.20.4-0.2-0.50.10.1-0.10.10.0-0.91.21.10.4-0.60.80.31.3
Delay disc. indifference point, 16s delay0.60.61.61.01.00.91.00.50.90.5-0.6-1.11.1-1.11.1-1.2-0.50.20.2-0.50.4-0.30.80.0
Delay disc. indifference point, 2s delay0.30.30.8-0.1-0.00.3-0.2-0.8-0.3-0.70.80.2-0.20.2-0.2-0.2-0.60.60.60.7-0.80.90.40.9
Delay disc. indifference point, 24s delay1.31.53.21.21.30.81.30.91.30.8-1.4-1.31.7-1.71.7-1.8-0.00.1-0.5-1.00.9-0.91.7-1.0
Delay disc. indifference point, 4s delay0.10.10.50.40.50.70.4-0.10.40.1-0.3-0.30.2-0.20.2-0.6-0.40.40.20.0-0.20.10.70.3
Delay disc. indifference point, 8s delay2.73.19.02.72.73.02.41.71.90.8-1.9-1.41.3-1.31.3-1.8-2.12.21.9-0.3-0.10.40.71.3
Indifference point function ln k0.20.31.1-0.8-0.9-1.1-0.8-0.6-0.7-0.5-0.00.2-0.40.4-0.40.10.5-0.8-0.50.10.0-0.20.3-0.6
Indifference point function log k0.20.31.1-0.8-0.9-1.1-0.8-0.6-0.7-0.5-0.00.2-0.40.4-0.40.10.5-0.8-0.50.10.0-0.20.3-0.6
Patch foraging total patch changes 0 sec1.63.08.42.82.82.92.52.32.01.3-0.9-1.31.4-1.41.4-0.9-1.81.82.1-0.60.30.0-1.01.0
Patch foraging total patch changes 12 sec1.52.05.12.22.22.32.11.81.81.4-1.0-1.11.3-1.31.3-1.1-1.01.21.0-0.80.5-0.2-0.30.6
Patch foraging total patch changes 18 sec2.94.410.63.23.23.03.13.12.82.0-2.1-1.42.2-2.22.2-1.3-1.21.71.1-1.41.0-0.7-0.10.4
Patch foraging total patch changes 24 sec2.33.99.93.03.13.03.02.72.61.9-1.7-1.41.8-1.81.8-1.8-1.51.91.2-1.10.6-0.4-0.10.6
Patch foraging total patch changes 6 sec2.74.110.73.33.33.13.02.92.51.9-1.6-1.41.8-1.81.8-0.8-1.62.11.8-0.90.6-0.1-0.31.1
Patch foraging time to switch 0 sec0.20.41.1-0.9-0.9-0.6-0.9-1.0-0.7-0.50.80.2-0.80.8-0.80.50.3-0.4-0.30.4-0.40.1-0.2-0.2
Patch foraging water rate 0 sec0.30.61.41.21.11.01.11.20.90.6-0.7-0.60.8-0.80.8-0.4-0.60.50.6-0.50.4-0.2-0.30.3
Patch foraging water rate 12 sec1.32.75.32.12.01.42.12.12.01.8-1.8-1.91.9-1.91.9-2.3-0.30.1-0.0-1.61.4-1.30.8-0.6
Patch foraging water rate 18 sec0.40.62.00.40.41.30.20.3-0.1-0.3-1.40.3-0.40.4-0.4-1.1-1.41.00.80.5-0.60.5-1.30.6
Patch foraging water rate 24 sec0.40.51.80.80.71.20.60.40.2-0.2-0.50.1-0.10.1-0.1-0.6-1.11.21.30.5-0.60.8-0.71.1
Patch foraging water rate 6 sec0.50.82.00.80.81.30.60.60.3-0.2-1.00.5-0.10.1-0.1-1.1-1.31.41.20.5-0.60.7-1.41.2
Seeking ratio, delayed vs. immediate footshock1.51.84.4-2.0-2.1-1.9-2.1-2.0-1.9-1.41.51.1-1.21.2-1.21.30.9-0.8-0.41.0-0.70.5-0.5-0.4
Distance traveled before self-admin2.73.55.4-1.8-1.7-1.0-2.0-2.2-2.2-2.32.12.2-2.32.3-2.31.0-0.80.91.02.3-2.22.2-0.81.8
Distance traveled after self-admin2.63.24.9-1.7-1.7-0.8-1.9-2.1-2.2-2.21.91.9-2.22.2-2.21.2-0.80.81.22.2-2.12.1-1.41.6
Extensor digitorum longus weight0.62.34.51.92.01.42.01.91.91.7-1.9-1.41.7-1.71.7-2.1-0.50.4-0.3-1.31.1-1.11.3-0.4
Bone: elastic displacement0.10.10.70.10.30.30.30.40.30.1-0.20.80.1-0.10.10.7-0.20.70.10.1-0.10.3-0.20.4
Bone: elastic work0.60.82.40.00.10.5-0.2-0.2-0.5-0.80.31.1-0.80.8-0.80.8-1.01.41.31.1-1.21.4-1.01.5
Bone: endosteal estimation0.81.84.32.12.01.61.91.81.71.5-0.2-1.71.4-1.41.4-1.3-0.50.50.8-1.10.8-0.7-0.20.1
Bone: endosteal perimeter2.24.711.83.43.43.33.12.82.41.7-1.3-1.51.6-1.61.6-2.5-2.42.52.4-0.60.20.2-1.21.6
Epididymis fat weight6.221.345.66.86.45.66.46.25.85.0-4.3-5.65.0-5.05.0-4.5-2.11.61.7-3.83.2-3.01.3-1.1
Delta time in closed arm before/after self-admin0.80.71.5-1.1-1.2-1.1-1.2-1.1-1.2-1.01.20.8-0.90.9-0.90.10.2-0.20.40.8-0.70.5-0.6-0.0
Delta time in open arm before/after self-admin2.32.35.41.91.91.42.02.32.12.0-2.0-1.41.4-1.41.4-1.0-0.20.1-0.5-1.61.3-1.50.8-0.9
Diff in mean of infusions in LGA sessions0.30.31.0-0.1-0.1-0.60.0-0.20.30.71.0-0.90.4-0.40.40.00.9-1.0-0.8-0.70.7-0.60.5-0.3
Delay discount exponential model param1.01.12.5-1.4-1.5-1.6-1.4-0.7-1.2-0.51.11.0-1.11.1-1.11.61.0-1.0-0.60.3-0.10.0-1.3-0.3
Extinction: sum of active levers before priming0.20.30.90.30.4-0.20.40.20.60.60.3-0.70.7-0.70.70.10.6-0.4-0.5-0.60.6-0.40.9-0.2
Active lever presses in extinction session 60.10.11.40.10.1-0.20.1-0.00.1-0.1-0.0-0.10.2-0.20.2-0.40.30.0-0.3-0.00.10.11.20.1
Bone: final force0.71.13.21.81.61.71.41.30.90.5-0.8-0.70.5-0.50.5-0.3-1.11.51.60.0-0.20.4-0.31.0
Bone: final moment0.71.13.41.91.71.71.51.41.00.7-0.8-0.90.7-0.70.7-0.3-1.01.41.5-0.1-0.00.3-0.10.8
Food consumed during 24 hour testing period0.60.83.5-1.3-1.3-1.9-1.1-0.9-0.7-0.20.30.3-0.20.2-0.20.81.5-1.2-1.1-0.10.4-0.31.2-0.8
Glucose0.71.14.01.61.51.61.51.61.20.9-2.0-0.40.8-0.80.8-0.8-1.01.10.6-0.40.2-0.2-0.10.2
Heart weight1.31.94.82.01.91.71.81.71.51.3-1.8-1.61.4-1.41.4-2.2-0.80.50.4-0.90.8-0.70.8-0.3
Delay discount hyperbolic model param0.80.82.2-1.2-1.4-1.5-1.2-0.5-1.0-0.41.00.8-0.80.8-0.81.41.0-1.0-0.50.20.0-0.1-1.2-0.4
Intermittent access intake day 1-15 change0.61.34.20.91.01.70.60.10.1-0.6-0.40.4-0.70.7-0.7-0.4-2.11.91.91.0-1.31.3-1.01.6
Intermittent access intake escalation0.40.82.91.01.11.50.80.40.3-0.3-0.60.1-0.30.3-0.3-0.5-1.71.61.40.6-0.90.9-0.61.2
Intermittent access intake escalation 20.80.92.90.40.41.10.1-0.2-0.3-0.8-0.50.7-0.90.9-0.9-0.5-1.71.61.41.2-1.31.1-0.71.1
Intermitt. access day 1 inactive lever presses0.93.56.42.42.52.02.52.52.52.0-2.4-1.91.9-1.91.9-1.8-0.40.3-0.3-1.81.5-1.51.3-0.9
Intermitt. access day 15 inactive lever presses0.30.62.41.11.21.21.21.21.00.6-1.5-0.00.3-0.30.3-0.6-0.90.90.1-0.40.1-0.30.4-0.1
Intermitt. access escalation Index0.20.30.8-0.7-0.7-0.9-0.7-0.6-0.5-0.40.50.2-0.20.2-0.20.30.7-0.6-0.70.2-0.0-0.30.1-0.7
Intermittent access day 1 total infusions0.10.20.70.20.20.60.0-0.2-0.2-0.5-0.20.2-0.40.4-0.4-0.2-0.70.80.80.6-0.60.6-0.60.5
Intermittent access day 15 total infusions0.60.82.60.60.61.30.3-0.1-0.1-0.7-0.50.5-0.70.7-0.7-0.6-1.61.61.31.0-1.21.1-0.71.1
Intermittent access terminal intake (last 3 days)0.40.51.70.50.61.10.3-0.1-0.0-0.5-0.40.4-0.60.6-0.6-0.8-1.31.30.90.8-1.00.8-0.30.8
Intermittent access total infusions0.80.92.80.80.71.50.40.1-0.0-0.6-1.10.5-0.60.6-0.6-0.8-1.71.71.31.0-1.10.9-0.70.9
Intermittent access day 1 locomotion1.01.33.40.20.31.3-0.1-0.5-0.6-1.2-0.11.0-1.01.0-1.0-0.1-1.71.81.51.5-1.61.6-1.21.5
Intermittent access day 15 total locomotion1.32.48.42.42.52.92.21.71.60.6-2.0-0.70.8-0.80.8-1.5-1.92.11.3-0.2-0.20.50.11.2
Intermittent access total locomotion1.72.16.00.60.62.00.2-0.3-0.5-1.4-0.91.1-1.21.2-1.2-0.4-2.42.51.91.7-1.91.9-1.51.7
Intermittent access standard deviation0.71.54.61.81.92.11.61.21.30.5-0.8-0.30.4-0.40.4-0.8-1.71.81.70.1-0.40.7-0.11.5
Left kidney weight0.42.06.91.61.52.31.20.90.5-0.1-0.30.1-0.30.3-0.3-0.3-2.42.32.60.8-1.11.2-2.01.8
Right kidney weight1.04.614.82.12.03.51.51.00.4-0.5-1.00.5-0.60.6-0.6-0.5-3.73.63.91.5-1.92.2-2.82.9
Cocaine induced anxiety2.13.07.5-2.7-2.6-2.2-2.5-2.4-2.2-1.80.92.3-1.71.7-1.70.91.0-0.7-1.41.4-1.10.40.0-1.2
Post-drug Anxiety0.50.52.2-0.7-0.5-0.9-0.3-0.1-0.00.3-0.40.30.3-0.30.3-0.41.1-0.8-1.5-0.40.5-0.81.1-1.3
Baseline Anxiety2.83.26.02.32.21.42.42.42.32.3-1.2-2.42.1-2.12.1-1.50.1-0.2-0.0-2.01.8-1.31.20.0
Tail length0.10.20.70.70.70.40.70.80.70.7-0.3-0.30.6-0.60.6-0.3-0.00.30.1-0.40.4-0.3-0.2-0.0
Length with tail0.52.14.22.01.81.31.92.01.81.9-0.9-1.91.7-1.71.7-0.8-0.00.10.2-1.51.4-1.30.3-0.8
Length without tail1.96.012.03.33.12.13.23.53.13.1-2.0-3.22.7-2.72.7-1.7-0.1-0.10.0-2.62.3-2.41.2-1.5
Times rat made contact with spout0.20.20.4-0.3-0.3-0.1-0.4-0.6-0.6-0.60.20.4-0.60.6-0.6-0.1-0.50.40.50.6-0.60.6-0.10.5
Lifetime Intake0.70.92.80.70.71.50.40.1-0.1-0.6-1.00.5-0.60.6-0.6-0.6-1.71.61.41.0-1.11.0-0.81.0
Liver weight, left2.44.011.33.03.03.42.82.42.31.6-2.1-1.61.5-1.51.5-2.7-2.21.71.4-0.90.4-0.4-0.70.6
Liver weight, right1.32.39.31.61.42.71.00.40.2-0.3-1.0-0.6-0.40.4-0.4-1.8-3.12.12.70.9-1.21.2-1.61.6
Locomotor activity0.50.72.10.60.61.20.40.40.0-0.3-1.00.4-0.40.4-0.4-0.7-1.51.31.30.7-0.80.8-1.40.9
Locomotor testing distance1.01.84.30.20.11.2-0.2-0.4-0.7-1.3-0.61.4-1.21.2-1.2-0.0-1.92.02.11.6-1.71.8-1.81.8
Locomotor testing rearing0.61.34.10.30.41.30.20.1-0.3-0.9-0.51.5-0.80.8-0.80.1-1.52.01.71.3-1.41.4-1.61.6
Locomotion in novel chamber1.82.34.6-1.9-2.0-1.3-2.1-2.1-2.1-1.81.41.3-2.02.0-2.01.4-0.2-0.30.21.5-1.40.8-1.0-0.0
Locomotion in novel chamber post-restriction1.62.65.5-2.2-2.3-1.7-2.3-2.2-2.3-1.91.41.6-1.91.9-1.91.20.2-0.4-0.11.6-1.30.9-0.9-0.3
Fecal boli incidents, locomotor time 10.50.71.51.01.01.10.91.00.60.1-1.20.30.6-0.60.6-0.1-0.81.21.20.1-0.10.6-0.81.2
Change in fecal boli incidents, locomotor task2.02.05.4-1.8-1.9-2.3-1.6-1.3-1.0-0.11.9-0.1-0.50.5-0.51.02.0-2.2-1.9-0.30.5-1.20.9-2.0
Time >=10cm from walls, locomotor time 11.51.66.0-1.6-1.6-2.5-1.3-0.9-0.9-0.10.90.4-0.10.1-0.1-0.31.9-1.9-2.1-0.30.6-1.01.3-1.7
Bouts of movement, locomotor time 11.21.43.71.81.91.91.71.31.50.6-1.2-0.71.2-1.21.2-0.0-0.81.41.0-0.40.20.30.50.9
Total resting periods, locomotor time 10.80.92.71.41.51.61.30.91.00.2-1.0-0.30.8-0.80.80.1-0.81.51.0-0.0-0.10.50.31.0
Rest time, locomotor task time 10.81.03.70.40.51.30.2-0.0-0.3-0.9-0.91.1-0.80.8-0.80.7-1.31.91.51.2-1.31.3-0.91.2
Distance moved, locomotor task time 10.20.31.2-0.1-0.0-0.30.10.10.30.30.0-0.30.7-0.70.7-1.10.5-0.7-1.1-0.60.6-0.50.3-0.5
Vertical activity count, locomotor time 10.30.82.2-1.4-1.3-1.4-1.2-1.0-0.8-0.50.60.4-0.10.1-0.1-1.20.9-1.3-1.5-0.00.2-0.40.4-1.0
Time >=10cm from walls, locomotor time 20.40.61.6-0.1-0.2-1.00.00.10.30.50.7-0.60.9-0.90.9-0.61.3-1.0-0.9-0.81.0-0.71.0-0.7
Bouts of movement, locomotor time 20.10.10.4-0.6-0.4-0.2-0.4-0.5-0.3-0.40.40.6-0.30.3-0.30.50.10.1-0.30.3-0.40.4-0.50.3
Total resting periods, locomotor time 20.10.10.4-0.10.10.3-0.0-0.3-0.0-0.30.00.5-0.20.2-0.20.2-0.30.50.00.4-0.50.6-0.50.7
Rest time, locomotor task time 20.50.61.90.60.71.10.50.30.2-0.3-0.50.5-0.30.3-0.30.5-1.11.41.30.6-0.80.9-0.61.3
Distance moved, locomotor task time 20.30.42.00.50.50.40.50.50.50.2-1.0-0.40.9-0.90.9-1.40.00.0-0.5-0.50.5-0.20.8-0.2
Vertical activity count, locomotor time 20.30.42.8-0.1-0.2-0.2-0.10.0-0.1-0.1-1.1-0.00.5-0.50.5-1.70.2-0.2-0.7-0.20.4-0.41.1-0.8
Light reinforcement 10.41.02.9-1.6-1.5-1.7-1.4-1.3-1.1-0.70.50.9-0.60.6-0.60.61.3-1.2-1.40.3-0.10.00.7-0.5
Light reinforcement 21.32.04.9-2.2-2.2-2.2-2.0-1.9-1.8-1.41.01.4-1.41.4-1.41.01.0-1.3-1.10.8-0.60.40.5-0.2
Bone: marrow area0.81.74.32.12.01.61.91.81.71.5-0.1-1.71.4-1.41.4-1.3-0.50.50.8-1.10.8-0.7-0.20.1
Bone: maximum diameter3.97.316.04.03.93.63.83.93.32.8-3.2-2.42.7-2.72.7-3.0-1.61.71.2-1.81.4-1.10.10.2
Bone: maximum force0.40.62.01.41.21.21.11.10.70.6-1.0-0.80.6-0.60.6-0.1-0.60.91.0-0.20.10.1-0.10.6
Bone: maximum moment0.40.72.01.41.21.11.21.20.80.7-0.9-0.90.7-0.70.7-0.1-0.40.70.8-0.30.3-0.10.20.3
Mean time between licks in bursts0.41.02.6-0.1-0.2-1.00.10.40.50.8-0.4-1.00.8-0.80.8-0.61.3-1.6-1.4-1.21.3-1.51.0-1.6
Mean num. licks in bursts1.42.23.7-0.9-1.0-0.0-1.2-1.4-1.6-1.80.11.7-1.91.9-1.90.8-1.41.31.41.9-1.91.8-1.51.5
Cd content in liver2.42.64.7-1.9-1.9-1.2-2.0-1.9-2.1-2.00.92.2-2.02.0-2.01.2-0.30.30.51.8-1.61.6-1.21.0
Co content in liver0.91.13.0-0.6-0.7-0.3-0.9-0.9-1.0-1.21.70.8-1.11.1-1.11.2-0.50.51.31.1-1.01.0-1.50.8
Cu content in liver0.30.40.9-0.4-0.40.2-0.5-0.6-0.6-0.80.10.7-0.70.7-0.7-0.1-0.70.30.50.7-0.70.7-1.00.6
Fe content in liver1.82.14.21.21.1-0.11.31.41.51.8-0.2-2.01.9-1.91.9-1.21.1-1.1-0.8-1.81.8-1.71.7-1.3
K content in liver0.30.31.9-0.2-0.10.4-0.2-0.3-0.2-0.50.70.7-0.40.4-0.4-0.2-0.50.60.70.5-0.60.7-1.40.8
Mg content in liver0.60.62.8-0.00.20.70.1-0.0-0.0-0.50.41.2-0.30.3-0.3-0.1-0.81.10.80.6-0.81.0-1.71.3
Mn content in liver0.20.20.8-0.4-0.30.0-0.3-0.5-0.3-0.50.80.7-0.50.5-0.50.6-0.10.30.20.5-0.50.6-0.90.6
Na content in liver0.10.10.50.10.20.40.2-0.10.1-0.00.60.3-0.00.0-0.0-0.7-0.30.40.30.2-0.30.5-0.70.7
Rb content in liver0.20.31.1-0.6-0.3-0.8-0.20.10.20.20.50.50.3-0.30.30.31.0-0.7-1.1-0.50.5-0.40.6-0.4
Se content in liver0.10.20.6-0.5-0.4-0.7-0.4-0.4-0.20.00.80.20.1-0.10.1-0.40.7-0.6-0.6-0.10.2-0.00.2-0.1
Sr content in liver2.52.24.0-1.7-1.7-1.0-1.8-2.0-1.8-1.91.61.5-1.91.9-1.91.40.1-0.00.41.5-1.41.4-0.80.8
Zn content in liver1.01.12.7-0.9-0.80.1-1.0-1.1-1.0-1.30.11.5-1.21.2-1.2-0.1-0.90.70.61.2-1.21.2-1.60.9
Bone: minimum diameter2.24.18.52.92.92.52.82.92.52.2-2.5-1.82.1-2.12.1-2.3-0.91.00.6-1.51.2-1.00.3-0.0
Time in familiar zone, hab. session 10.20.20.8-0.3-0.3-0.1-0.4-0.4-0.5-0.50.30.6-0.50.5-0.50.5-0.40.40.50.6-0.50.6-0.90.5
Time in novel zone, hab. session 11.11.12.01.11.10.71.21.21.21.2-0.9-1.31.2-1.21.2-0.90.3-0.3-0.5-1.11.0-1.01.4-0.8
Total zone transitions, hab. session 10.71.03.50.60.51.40.2-0.2-0.3-0.7-0.20.3-0.70.7-0.7-0.5-1.91.61.51.1-1.31.3-0.91.5
Total locomotion distance, hab. session 10.20.30.8-0.8-0.8-0.8-0.7-0.5-0.5-0.10.20.0-0.30.3-0.3-0.00.8-0.9-0.9-0.10.2-0.30.4-0.6
Locomotion velocity, hab. session 10.30.41.1-1.0-1.1-0.9-1.0-0.9-0.8-0.40.40.2-0.50.5-0.50.10.8-1.0-0.90.10.0-0.20.4-0.6
Time in familiar zone, hab. session 22.72.85.71.81.70.61.91.72.02.0-0.4-2.42.0-2.02.0-1.80.5-0.7-0.6-1.91.8-1.72.1-1.2
Time in novel zone, hab. session 22.02.13.6-1.3-1.4-0.3-1.5-1.4-1.8-1.8-0.21.9-1.81.8-1.81.5-0.80.70.71.8-1.61.5-1.71.0
Total zone transitions, hab. session 20.81.03.90.90.81.80.60.10.0-0.4-0.3-0.1-0.40.4-0.4-0.9-2.01.51.50.8-1.01.0-1.41.3
Total locomotion distance, hab. session 20.00.10.4-0.2-0.20.2-0.2-0.3-0.3-0.1-0.2-0.1-0.30.3-0.3-0.4-0.2-0.2-0.10.1-0.10.0-0.7-0.1
Locomotion velocity, hab. session 20.10.10.7-0.2-0.20.2-0.3-0.3-0.3-0.3-0.00.1-0.40.4-0.4-0.4-0.3-0.00.10.3-0.30.2-0.90.1
Novel to familiar place preference ratio0.70.82.3-0.0-0.1-0.10.10.60.40.8-1.5-0.60.8-0.80.8-0.00.9-1.2-1.2-1.01.2-1.30.4-1.5
Novelty place preference0.50.62.2-0.0-0.1-0.10.10.50.40.6-1.5-0.40.7-0.70.70.00.8-1.0-1.0-0.81.0-1.10.2-1.3
Time in novel zone, NPP test1.01.13.20.50.40.30.61.00.81.1-1.8-1.01.2-1.21.2-0.50.7-1.0-1.1-1.21.3-1.40.5-1.5
Total zone transitions, NPP test0.30.41.50.40.31.10.1-0.3-0.2-0.50.2-0.0-0.40.4-0.4-0.4-1.21.01.10.7-0.80.8-0.71.0
Total locomotion distance, NPP test0.10.20.6-0.5-0.7-0.5-0.6-0.6-0.5-0.20.5-0.3-0.10.1-0.10.10.5-0.8-0.4-0.00.1-0.20.0-0.5
Locomotion velocity, NPP test0.40.61.5-1.1-1.2-0.9-1.2-1.2-1.0-0.71.00.3-0.70.7-0.70.60.6-0.8-0.30.4-0.30.2-0.3-0.2
Intraocular pressure1.82.66.22.52.31.82.22.11.91.7-1.3-2.01.6-1.61.6-2.1-1.00.90.7-1.10.9-0.81.1-0.1
Delta distance traveled before/after self-admin0.20.21.00.10.10.60.0-0.2-0.1-0.3-0.30.1-0.30.3-0.30.1-0.60.50.50.4-0.50.3-1.0-0.0
Delta ambulatory time before/after self-admin0.10.20.50.50.50.70.50.30.40.2-0.6-0.40.5-0.50.5-0.1-0.30.20.2-0.20.1-0.2-0.4-0.3
Parametrial fat weight8.119.143.36.66.55.76.35.95.54.3-4.5-4.44.3-4.34.3-5.1-2.82.61.8-3.12.3-2.11.5-0.1
Pavlov. Cond. lever latency0.30.40.90.80.90.50.91.01.00.8-0.3-0.30.8-0.80.8-0.60.10.2-0.1-0.70.6-0.5-0.0-0.2
Pavlov. Cond. magazine entry latency0.20.20.7-0.5-0.6-0.5-0.5-0.6-0.4-0.10.3-0.4-0.20.2-0.20.10.5-0.8-0.5-0.10.2-0.40.9-0.7
Pavlov. Cond. change in total contacts0.10.10.4-0.3-0.5-0.2-0.5-0.6-0.5-0.30.3-0.4-0.30.3-0.30.00.1-0.4-0.00.2-0.1-0.00.3-0.2
Pavlov. Cond. index score0.10.10.2-0.3-0.4-0.1-0.4-0.4-0.4-0.20.1-0.2-0.30.3-0.30.10.1-0.2-0.00.2-0.1-0.00.3-0.2
Pavlov. Cond. latency score0.10.10.2-0.3-0.4-0.0-0.4-0.5-0.5-0.30.1-0.1-0.40.4-0.40.2-0.2-0.00.10.3-0.30.20.10.0
Pavlov. Cond. lever contacts0.10.10.3-0.3-0.4-0.1-0.4-0.6-0.5-0.40.4-0.0-0.50.5-0.50.6-0.1-0.10.20.4-0.30.30.10.2
Pavlov. Cond. magazine entry number0.00.00.3-0.10.1-0.10.10.10.20.10.20.30.2-0.20.20.1-0.10.0-0.1-0.10.10.0-0.50.2
Pavlov. Cond. intertrial magazine entries0.20.20.8-0.5-0.7-0.9-0.6-0.4-0.6-0.20.3-0.2-0.20.2-0.20.70.6-0.7-0.2-0.00.2-0.20.1-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.3-0.4-0.3-0.4-0.4-0.3-0.10.1-0.4-0.10.1-0.10.10.3-0.5-0.3-0.00.1-0.20.6-0.4
Pavlov. Cond. response bias0.20.20.6-0.6-0.7-0.6-0.7-0.8-0.7-0.40.3-0.1-0.50.5-0.50.40.4-0.5-0.20.3-0.20.00.7-0.3
Pavlov. Cond. lever latency0.81.01.5-1.1-1.1-0.9-1.2-1.2-1.2-1.21.21.2-1.21.2-1.21.00.10.20.31.1-1.01.1-0.40.8
Pavlov. Cond. magazine entry latency0.70.92.81.21.20.91.21.01.21.0-0.7-1.21.0-1.01.0-1.7-0.3-0.1-0.2-0.90.7-0.80.5-0.4
Pavlov. Cond. change in total contacts0.91.43.41.41.41.31.51.71.51.4-1.9-0.91.4-1.41.4-0.9-0.10.2-0.3-1.11.0-1.00.2-0.7
Pavlov. Cond. index score0.91.22.31.41.31.21.41.41.31.2-1.5-1.11.2-1.21.2-1.3-0.40.1-0.2-1.00.9-1.00.2-0.7
Pavlov. Cond. latency score1.01.32.61.41.41.21.41.51.41.3-1.6-1.11.3-1.31.3-1.2-0.40.1-0.2-1.10.9-1.00.2-0.7
Pavlov. Cond. lever contacts0.30.50.80.90.80.90.90.90.80.8-0.9-0.70.8-0.80.8-0.8-0.30.10.1-0.60.5-0.6-0.0-0.4
Pavlov. Cond. magazine entry number0.60.82.2-1.1-1.1-0.9-1.2-1.1-1.2-1.00.51.1-1.01.0-1.01.50.2-0.00.10.9-0.70.8-0.10.4
Pavlov. Cond. intertrial magazine entries0.10.10.50.40.50.60.40.10.30.20.2-0.10.2-0.20.20.1-0.20.50.40.1-0.20.40.60.7
Pavlov. Cond. lever-magazine prob. diff.0.71.02.11.31.31.31.31.31.21.0-1.5-1.01.0-1.01.0-1.2-0.50.20.0-0.80.7-0.80.0-0.5
Pavlov. Cond. response bias0.71.01.61.21.10.91.21.21.21.2-1.0-1.21.2-1.21.2-1.3-0.1-0.2-0.2-1.00.9-1.00.4-0.7
Time in closed arm before self-admin0.10.20.6-0.2-0.00.3-0.2-0.4-0.3-0.7-0.50.7-0.30.3-0.30.3-0.40.7-0.20.6-0.70.40.3-0.0
Time in closed arm after self-admin1.31.42.9-1.4-1.3-0.8-1.4-1.5-1.5-1.60.81.7-1.41.4-1.41.0-0.20.50.21.5-1.40.9-0.60.0
Time in open arm before self-admin1.11.24.4-1.4-1.5-2.1-1.3-1.0-0.80.01.7-0.20.1-0.10.10.41.8-2.0-1.1-0.40.8-0.50.7-0.7
Time in open arm after self-admin0.70.82.00.80.70.40.91.31.01.4-0.9-1.10.9-0.90.9-0.60.3-0.7-0.5-1.31.2-1.10.5-0.5
Bone: periosteal estimation2.14.411.03.33.12.93.03.02.52.1-2.1-2.02.0-2.02.0-2.1-1.41.51.4-1.31.0-0.7-0.20.4
Bone: periosteal perimeter4.98.520.64.54.54.44.13.93.22.3-2.9-1.82.2-2.22.2-3.5-3.13.22.7-0.90.40.1-0.71.7
Bone: post-yield work0.81.13.8-0.3-0.5-1.1-0.2-0.10.20.70.0-1.20.7-0.70.7-0.81.4-1.9-1.5-1.11.2-1.31.9-1.5
Progressive ratio test 1 active lever presses1.01.23.50.50.51.50.2-0.2-0.3-0.9-1.00.7-0.80.8-0.8-0.9-1.91.71.51.2-1.41.3-1.21.4
Progressive ratio test 1 breakpoint1.01.23.50.40.41.50.1-0.3-0.4-1.0-0.90.8-0.80.8-0.8-0.9-1.91.61.51.3-1.41.4-1.31.4
Progressive ratio test 1 inactive lever presses0.10.10.60.30.30.50.20.00.0-0.2-0.30.1-0.10.1-0.1-0.8-0.70.60.20.3-0.30.20.10.0
Progressive ratio test 2 active lever presses1.11.34.51.41.42.11.10.70.6-0.2-1.70.1-0.20.2-0.2-1.2-2.01.81.30.6-0.90.8-0.61.0
Progressive ratio test 2 breakpoint1.11.34.61.41.42.11.10.70.6-0.2-1.70.1-0.10.1-0.1-1.2-2.01.81.20.6-0.90.7-0.50.9
Progressive ratio test 2 inactive lever presses0.61.02.41.51.51.51.41.31.10.7-1.5-0.70.6-0.60.6-1.0-1.01.00.6-0.40.2-0.20.40.1
Incentive Sensitization - Responses0.60.92.51.51.51.61.41.11.10.5-1.5-0.50.6-0.60.6-1.0-1.01.10.6-0.2-0.00.00.20.3
Incentive Sensitization - Breakpoint0.70.92.31.41.51.51.41.21.10.6-1.5-0.60.6-0.60.6-1.0-0.90.90.4-0.30.1-0.10.30.1
Sum of active levers in priming session hrs 5-60.00.00.2-0.00.0-0.10.00.10.10.30.1-0.20.2-0.20.20.20.2-0.4-0.5-0.30.3-0.20.1-0.1
Progressive ratio0.10.20.6-0.5-0.4-0.7-0.3-0.2-0.10.10.50.1-0.00.0-0.00.50.8-0.7-0.8-0.30.3-0.40.1-0.4
Food seeking constrained by brief footshock0.70.94.9-0.10.1-0.50.2-0.10.50.50.1-0.61.0-1.01.0-0.01.2-0.8-1.5-0.70.8-1.02.2-1.5
Seeking ratio, punishment vs. effort0.10.10.50.30.30.50.2-0.20.0-0.3-0.30.1-0.10.1-0.1-0.4-0.70.70.40.4-0.50.30.30.1
Retroperitoneal fat weight6.929.464.78.07.76.57.67.16.95.8-4.7-6.55.6-5.65.6-5.9-2.82.12.0-4.33.5-3.42.0-1.1
Reaction time number correct0.61.22.81.61.71.61.51.31.20.8-1.6-0.50.9-0.90.9-1.3-1.21.20.6-0.30.10.20.40.9
Reaction time mean minus median0.20.51.70.80.81.20.60.50.30.0-1.00.2-0.30.3-0.3-0.7-1.31.20.90.4-0.60.4-0.80.7
Reaction time mean minus median AUC0.51.33.80.40.51.30.2-0.1-0.3-0.8-0.41.1-1.11.1-1.1-0.2-1.91.91.71.3-1.51.4-1.31.6
Reaction time num false alarms0.10.20.5-0.3-0.5-0.2-0.5-0.7-0.6-0.50.7-0.3-0.30.3-0.3-0.1-0.3-0.40.40.3-0.20.1-0.40.1
Reaction time num false alarms AUC0.20.30.7-0.3-0.50.0-0.6-0.8-0.7-0.80.6-0.0-0.50.5-0.5-0.0-0.6-0.00.70.6-0.50.5-0.80.4
Reaction time trials correct on left0.61.22.81.61.71.61.51.31.20.8-1.6-0.50.9-0.90.9-1.3-1.21.20.6-0.30.10.20.40.9
Reaction time trials on left0.71.33.01.71.71.71.61.31.30.8-1.6-0.50.9-0.90.9-1.3-1.21.30.7-0.30.10.20.40.9
Reaction time mean0.30.52.30.50.51.10.30.1-0.0-0.3-0.50.1-0.60.6-0.6-0.1-1.31.01.10.6-0.70.5-1.50.5
Reaction time mean AUC0.30.52.40.30.31.00.1-0.0-0.1-0.4-0.60.4-0.70.7-0.7-0.2-1.31.01.00.6-0.80.6-1.60.6
Median of all reaction times0.40.52.60.30.20.90.0-0.2-0.2-0.4-0.20.1-0.70.7-0.70.1-1.20.91.20.7-0.80.6-1.60.5
Reaction time omissions0.50.71.81.31.31.21.31.11.10.9-0.4-0.90.6-0.60.6-0.6-0.70.60.4-0.50.3-0.40.20.0
Reaction time false alarm rate0.50.61.9-1.0-1.2-0.9-1.2-1.3-1.1-0.81.4-0.2-0.60.6-0.60.40.3-1.00.00.4-0.2-0.1-0.5-0.5
Reaction time premature initiation rate1.01.42.2-0.5-0.60.3-0.9-1.0-1.2-1.40.61.1-1.41.4-1.41.1-1.01.11.21.5-1.51.5-1.41.2
Reaction time premature initiations0.71.33.90.40.41.30.1-0.2-0.5-0.9-0.61.0-0.90.9-0.90.4-1.72.01.61.3-1.51.6-1.31.8
Std. dev. reaction times0.61.23.81.51.42.01.21.00.70.3-1.3-0.3-0.00.0-0.0-0.9-1.91.71.50.3-0.60.4-1.30.7
Reaction time trials completed0.71.33.01.71.71.71.61.31.30.8-1.6-0.50.9-0.90.9-1.3-1.21.30.7-0.30.10.20.40.9
Reaction time trials AUC0.71.32.91.61.71.71.61.31.20.8-1.6-0.50.9-0.90.9-1.2-1.21.30.7-0.30.10.20.40.9
Run reversals in cocaine runway, females0.40.42.00.60.51.00.40.60.10.0-1.0-0.0-0.50.5-0.5-0.2-1.40.80.90.3-0.4-0.0-1.2-0.0
Run reversals in cocaine runway, males0.50.51.8-1.1-0.8-0.8-0.8-1.0-0.7-0.80.41.4-0.00.0-0.01.00.80.2-0.60.6-0.40.8-0.00.5
Latency to leave start box in cocaine runway0.10.10.8-0.20.1-0.20.10.20.30.60.90.40.1-0.10.10.60.50.1-0.1-0.20.20.1-0.20.4
Latency to leave start box in cocaine runway, F0.30.31.2-0.7-0.4-0.8-0.3-0.10.00.21.00.60.1-0.10.11.11.1-0.3-0.7-0.30.4-0.1-0.00.1
Latency to leave start box in cocaine runway, M0.40.41.10.91.01.00.90.60.70.90.1-0.20.1-0.10.1-0.7-0.80.80.8-0.0-0.20.2-0.20.6
Std. dev. time between licks in bursts0.60.82.9-0.4-0.6-1.2-0.3-0.10.00.40.9-1.00.4-0.40.40.11.6-1.7-1.1-0.91.0-1.20.7-1.4
Total sessions with >9 infusions0.81.03.71.11.01.60.70.50.2-0.3-0.8-0.1-0.30.3-0.3-0.4-1.71.61.90.7-0.80.9-1.11.3
Short access day 1 total inactive lever presses0.50.61.8-0.4-0.4-1.0-0.2-0.00.20.50.5-0.70.6-0.60.60.31.3-1.3-1.1-0.80.9-1.01.1-1.2
Short access day 10 total inactive lever presses0.10.20.60.60.60.80.50.50.40.2-0.4-0.10.0-0.00.0-0.4-0.80.70.50.0-0.20.2-0.20.5
Short access day 1 total infusions0.40.51.3-0.1-0.20.4-0.4-0.5-0.6-0.80.10.5-0.90.9-0.90.4-1.00.81.11.0-1.00.9-0.80.8
Short access day 10 total infusions1.11.42.4-0.6-0.60.3-0.9-1.1-1.2-1.50.41.2-1.31.3-1.30.8-1.11.11.31.6-1.51.5-1.51.3
Short access total infusions0.70.91.7-0.2-0.30.5-0.5-0.6-0.9-1.1-0.21.0-1.11.1-1.10.4-1.21.21.31.3-1.31.1-1.11.0
Short access day 1 locomotion0.91.13.50.70.71.50.4-0.2-0.0-0.70.10.2-0.50.5-0.50.2-1.61.71.91.0-1.21.4-1.11.7
Short access day 10 total locomotion0.81.54.61.11.12.10.70.10.0-0.8-0.90.4-0.60.6-0.6-0.3-2.12.22.01.1-1.41.5-0.91.6
Short access total locomotion1.92.36.40.80.82.10.3-0.3-0.4-1.3-0.50.8-1.11.1-1.10.1-2.42.52.41.7-1.92.1-1.52.2
One hour access (0.3 mA shock)0.91.02.91.41.41.31.41.21.31.0-1.3-1.00.9-0.90.9-1.7-0.60.50.1-0.70.5-0.70.4-0.5
Compulsive drug intake0.81.01.90.20.2-0.60.40.50.71.10.2-1.31.1-1.11.1-1.10.9-1.4-1.1-1.31.3-1.41.1-1.3
One hour access (shock baseline)0.60.93.20.80.81.50.60.30.1-0.5-0.90.6-0.60.6-0.6-0.1-1.51.81.40.9-1.11.0-1.01.1
Social response proportion1.21.33.70.2-0.10.9-0.4-0.7-0.9-1.10.10.4-1.41.4-1.4-0.2-1.91.41.71.4-1.51.3-1.71.2
Social responses2.02.67.72.52.42.82.21.81.61.1-2.1-1.20.9-0.90.9-2.1-2.11.91.4-0.40.0-0.0-0.50.6
Social time0.91.24.40.90.81.70.50.1-0.0-0.5-0.50.2-0.70.7-0.7-0.3-2.11.81.70.9-1.21.1-1.61.3
Soleus weight1.44.012.62.52.43.41.81.10.8-0.1-0.8-0.3-0.10.1-0.1-1.2-3.63.43.51.2-1.61.8-1.72.7
Bone: stiffness0.30.41.21.11.01.00.90.90.50.3-0.9-0.40.3-0.30.3-0.4-0.60.91.10.0-0.10.3-0.30.6
Tibialis anterior weight0.51.63.11.61.61.21.71.81.61.5-1.6-0.91.5-1.51.5-1.7-0.30.5-0.1-1.10.9-0.80.7-0.3
Time to tail flick, vehicle, before self-admin0.30.31.30.60.70.60.70.90.60.5-1.1-0.10.4-0.40.4-0.5-0.20.3-0.2-0.30.3-0.50.5-0.5
Time to tail flick, vehicle, after self-admin0.10.10.3-0.10.0-0.20.10.10.20.30.00.00.4-0.40.4-0.20.5-0.2-0.3-0.30.30.10.60.4
Time to tail flick, test, before self-admin4.14.37.4-1.1-1.10.2-1.6-2.0-2.1-2.71.22.1-2.42.4-2.41.0-2.01.92.32.7-2.72.6-2.22.2
Time to tail flick, test, after self-admin0.90.94.91.11.11.21.11.21.00.8-2.2-0.50.9-0.90.9-1.1-0.40.4-0.3-0.60.5-0.50.9-0.4
Delta time to tail flick, vehicle, before/after SA0.50.51.00.70.80.40.80.70.90.80.0-0.81.0-1.01.0-0.40.4-0.2-0.1-0.80.7-0.20.80.6
Delta time to tail flick, test, before/after SA1.71.86.21.31.30.91.41.81.51.5-2.5-0.91.6-1.61.6-0.60.4-0.3-0.9-1.41.4-1.31.0-1.0
Tibia length0.41.13.71.21.01.90.70.40.1-0.3-0.2-0.2-0.40.4-0.4-0.1-1.81.61.90.8-1.01.1-1.51.4
Ambulatory time before self-admin1.52.33.9-1.1-1.1-0.4-1.4-1.6-1.7-1.91.41.7-1.91.9-1.90.4-1.01.21.22.0-2.01.9-0.71.7
Ambulatory time after self-admin1.82.23.8-1.0-1.0-0.2-1.3-1.7-1.6-1.91.41.6-1.81.8-1.80.6-1.01.11.31.9-1.91.9-1.11.5
Bone: tissue strength0.10.10.8-0.10.0-0.50.10.20.20.30.4-0.00.2-0.20.20.30.5-0.2-0.4-0.30.3-0.30.9-0.2
Total heroin consumption1.11.22.81.71.71.41.61.31.41.0-0.7-1.31.1-1.11.1-1.5-0.60.60.4-0.80.6-0.10.80.7
Bone: trabecular number1.82.97.21.51.40.31.61.61.82.0-1.3-2.42.0-2.02.0-1.21.0-1.1-1.2-2.01.9-1.92.7-1.6
Bone: trabecular spacing0.00.00.2-0.2-0.10.0-0.10.0-0.0-0.1-0.10.4-0.00.0-0.0-0.1-0.20.0-0.1-0.00.0-0.0-0.5-0.1
Bone: trabecular thickness2.83.48.22.92.82.32.72.52.42.0-1.8-2.02.0-2.02.0-1.5-0.81.20.9-1.31.0-0.80.70.2
Bone: trabecular tissue density0.71.04.9-0.1-0.20.6-0.3-0.3-0.6-0.8-0.21.1-0.90.9-0.90.2-1.31.21.51.1-1.11.2-2.21.1
Water consumed over 24 hours0.20.30.7-0.2-0.30.0-0.4-0.5-0.6-0.60.10.6-0.60.6-0.60.5-0.50.60.70.8-0.70.8-0.30.8
Number of responses in last shaping day1.21.43.0-0.2-0.20.5-0.4-0.6-0.8-1.20.71.2-1.21.2-1.20.8-1.31.61.61.5-1.61.6-1.31.7