Best TWAS P=1.52065e-09 · Best GWAS P=2.052553e-06 conditioned to 0.8710205
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Brain | NA | gene expression | ENSRNOG00000070389 | 0.05 | 0.05 | enet | 121 | 0.05 | 1.9e-05 | -4.1 | -6 | 1.5e-09 | 0.8 | 0.61 | 0.39 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.