Hub : Genes

Stac2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_063269538.1 0.03 0.04 6.2e-03 0.01 0.01 0.01 0.01 1.2e-02 9.8e-03 2.8e-02 1.8e-02
2 Brain gene expression Stac2 0.07 0.05 5.2e-07 0.05 0.07 0.06 0.06 1.7e-05 7.0e-07 3.5e-06 4.1e-06
3 IL gene expression Stac2 0.19 0.16 1.8e-03 0.09 0.02 0.11 0.07 3.7e-03 1.1e-01 1.6e-03 7.4e-03
4 NAcc gene expression Stac2 0.03 0.02 1.4e-04 0.02 0.02 0.01 0.02 4.7e-04 2.0e-04 2.4e-03 1.5e-03
5 PL mRNA stability Stac2 0.02 0.02 4.5e-03 0.02 0.02 0.01 0.01 2.9e-03 2.5e-03 2.1e-02 7.5e-03
6 LHb gene expression Stac2 0.18 0.17 5.9e-03 0.06 0.02 0.1 0.03 1.3e-02 8.8e-02 1.9e-03 7.5e-02
7 OFC gene expression Stac2 0.3 0.25 8.4e-04 0.06 0.03 0.04 0.04 1.7e-02 7.0e-02 4.9e-02 4.4e-02
8 PL gene expression Stac2 0.12 0.08 2.9e-12 0.1 0.1 0.1 0.11 2.2e-11 4.5e-11 2.0e-11 1.4e-11
9 IC gene expression Stac2 0.13 0.12 8.8e-04 0.07 0.07 0.06 0.07 6.8e-04 4.6e-04 1.5e-03 6.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.83.35.7-1.92.0-2.41.91.8-0.9-1.91.51.8
Area under the delay curve0.60.91.2-1.01.0-0.61.11.1-1.1-0.90.61.1
BMI with tail2.27.710.22.7-2.72.3-2.7-2.63.22.8-3.2-2.5
BMI without tail1.15.711.32.4-2.31.2-2.3-2.33.41.7-3.0-2.4
Body weight7.532.936.06.0-5.94.9-5.9-5.96.05.2-5.9-5.8
Weight adjusted by age0.10.20.70.3-0.40.7-0.3-0.4-0.30.8-0.3-0.3
Bone surface0.00.10.4-0.10.1-0.7-0.0-0.00.5-0.2-0.1-0.1
Bone volume0.10.20.8-0.40.4-0.90.40.40.0-0.50.40.3
Breakpoint value in progressive ratio session1.12.03.01.6-1.50.8-1.6-1.51.50.6-1.4-1.7
Number of licking bursts0.20.61.0-0.80.8-0.30.80.8-0.9-0.51.00.9
Context. condit. distance diff. score0.50.71.70.8-0.81.3-0.7-0.70.31.1-0.4-0.6
Locomotion velocity, session 10.70.81.40.9-1.00.6-1.0-1.01.20.6-0.4-1.0
Locomotion distance, session 13.95.08.52.3-2.21.1-2.3-2.32.91.5-2.5-2.4
Locomotion velocity, session 20.70.82.20.8-0.80.3-0.9-0.91.50.5-0.8-1.0
Locomotion distance, session 21.21.74.61.1-1.1-0.2-1.2-1.22.10.2-1.8-1.4
Locomotion velocity, session 30.30.31.40.4-0.3-0.4-0.4-0.41.20.1-0.8-0.5
Locomotion distance, session 30.50.61.10.7-0.70.2-0.8-0.81.00.5-1.1-0.8
Stereotopy head waving bouts, day 33.23.94.4-2.02.1-2.02.12.1-1.6-1.91.72.1
Stereotopy head waving duration, day 30.50.60.8-0.80.9-0.70.90.9-0.6-0.60.70.9
Locomotion velocity, session 70.80.91.71.0-1.01.3-1.0-0.90.50.9-0.7-0.9
Locomotion distance, session 70.20.20.80.5-0.40.9-0.3-0.3-0.50.40.0-0.3
Stereotopy head waving bouts, day 71.31.52.0-1.41.3-1.21.31.3-0.9-1.10.91.4
Stereotopy head waving duration, day 70.30.40.6-0.80.7-0.80.70.6-0.2-0.60.20.8
Locomotion velocity, session 86.88.29.43.0-3.03.1-2.9-2.92.43.0-2.4-2.9
Locomotion distance, session 81.62.43.01.6-1.61.2-1.6-1.61.61.3-1.7-1.6
Degree of sensitization distance0.40.41.80.6-0.61.3-0.5-0.5-0.40.80.1-0.4
Degree of sensitization stereotypy1.71.92.6-1.51.4-1.21.51.5-1.3-1.11.21.6
Conditioned locomotion0.20.20.4-0.40.4-0.30.50.5-0.7-0.50.40.4
Cocaine response after cond. corrected1.92.83.2-1.81.7-1.51.71.6-1.8-1.41.71.8
Cocaine response after cond. not corrected2.84.15.7-2.12.0-1.52.02.0-2.4-1.52.32.1
Cocaine response before conditioning0.60.72.0-0.60.7-0.10.80.8-1.4-0.31.10.8
Saline control response0.20.21.20.0-0.00.70.10.1-1.10.30.40.2
Bone: connectivity density2.64.27.8-2.22.2-2.82.12.1-0.9-2.21.52.0
Bone: cortical apparent density4.67.39.0-2.82.8-2.62.72.7-2.4-2.63.02.6
Bone: cortical area0.20.41.0-0.50.5-0.30.60.6-0.9-0.51.00.6
Bone: cortical porosity1.01.12.3-1.01.0-0.41.01.0-1.5-0.91.31.0
Bone: cortical porosity1.01.12.6-0.90.9-0.21.01.0-1.6-0.81.41.0
Bone: cortical thickness1.62.63.9-1.71.6-1.31.71.6-1.6-1.32.01.7
Bone: cortical thickness4.45.46.2-2.42.4-2.12.42.4-2.1-2.22.52.3
Bone: cortical tissue density4.67.39.0-2.82.8-2.72.72.7-2.4-2.63.02.6
Condit. Reinf. active minus inactive responses0.50.61.7-0.70.8-1.30.70.70.2-1.10.60.5
Condit. Reinf. active-inactive response ratio0.70.71.6-0.80.9-1.20.90.9-0.2-1.10.60.7
Condit. Reinf. active responses0.70.91.4-1.01.0-1.20.90.9-0.3-1.01.10.8
Condit. Reinf. inactive responses0.50.61.5-0.80.7-0.20.80.8-0.9-0.21.20.8
Incentive salience index mean1.41.83.1-1.31.3-1.81.31.3-0.5-1.61.41.1
Condit. Reinf. lever presses1.31.93.2-1.31.4-1.61.31.3-0.8-1.51.81.2
Condit. Reinf. active minus inactive responses0.40.71.0-0.90.8-0.70.80.8-0.8-0.81.00.8
Condit. Reinf. active-inactive response ratio0.30.40.7-0.70.7-0.80.70.6-0.3-0.80.50.6
Condit. Reinf. active responses0.81.21.5-1.11.1-1.11.11.1-0.9-1.11.21.0
Condit. Reinf. inactive responses1.42.12.8-1.31.4-1.31.41.5-1.5-1.51.71.3
Condit. Reinf. lever presses0.00.00.1-0.20.1-0.30.10.10.1-0.2-0.00.1
Condit. Reinf. lever reinforcers received0.91.21.5-1.11.1-1.21.11.1-0.8-1.21.21.0
Conditioned reinforcement - actives0.31.14.4-0.60.70.20.90.9-2.1-0.31.60.9
Conditioned reinforcement - inactives0.00.00.10.00.1-0.30.10.10.2-0.40.2-0.0
Conditioned locomotion1.11.72.7-1.31.2-0.71.31.3-1.5-1.01.71.4
Patch foraging indifference point 0 sec0.82.44.0-1.51.6-1.81.51.5-1.4-2.01.01.4
Patch foraging indifference point AUC0.00.00.1-0.20.1-0.10.0-0.0-0.1-0.40.30.0
Delay disc. indifference point, 0s delay1.92.12.7-1.51.5-1.11.51.5-1.4-1.61.41.5
Delay disc. indifference point, 16s delay0.50.81.7-0.90.8-0.50.90.9-1.3-0.70.80.9
Delay disc. indifference point, 2s delay2.52.84.7-1.61.7-1.21.71.7-2.2-1.51.71.7
Delay disc. indifference point, 24s delay0.00.00.1-0.20.10.30.20.2-0.3-0.0-0.00.3
Delay disc. indifference point, 4s delay0.90.91.5-1.11.0-0.60.90.9-1.2-0.90.91.0
Delay disc. indifference point, 8s delay0.20.40.7-0.60.7-0.40.80.8-0.5-0.6-0.00.8
Indifference point function ln k0.00.00.30.00.0-0.20.10.10.10.2-0.50.1
Indifference point function log k0.00.00.30.00.0-0.20.10.10.10.2-0.50.1
Patch foraging total patch changes 0 sec0.51.63.1-1.21.2-1.61.21.2-1.0-1.80.71.1
Patch foraging total patch changes 12 sec4.25.76.9-2.42.5-2.32.42.4-2.3-2.62.22.3
Patch foraging total patch changes 18 sec0.20.50.8-0.70.6-0.60.60.6-0.8-0.90.80.6
Patch foraging total patch changes 24 sec0.72.22.8-1.71.5-1.21.51.5-1.6-1.21.51.7
Patch foraging total patch changes 6 sec1.22.03.8-1.41.4-1.91.31.3-0.7-2.01.11.2
Patch foraging time to switch 0 sec0.00.00.1-0.10.1-0.20.10.10.1-0.2-0.00.1
Patch foraging water rate 0 sec0.00.00.4-0.10.1-0.60.10.10.0-0.2-0.10.0
Patch foraging water rate 12 sec0.10.50.90.6-0.71.0-0.7-0.70.30.9-0.5-0.6
Patch foraging water rate 18 sec0.20.50.9-0.70.8-0.90.80.8-0.2-0.40.30.7
Patch foraging water rate 24 sec0.20.31.0-0.40.6-1.00.50.6-0.2-0.50.30.4
Patch foraging water rate 6 sec0.91.32.7-1.11.2-1.61.11.1-0.6-1.21.11.0
Seeking ratio, delayed vs. immediate footshock0.20.30.70.3-0.30.6-0.4-0.4-0.80.30.7-0.5
Distance traveled before self-admin0.10.20.50.6-0.50.4-0.5-0.5-0.10.0-0.0-0.7
Distance traveled after self-admin0.81.32.51.4-1.20.6-1.2-1.11.60.8-1.0-1.3
Extensor digitorum longus weight8.032.041.75.8-6.06.5-5.8-5.84.36.1-4.6-5.6
Bone: elastic displacement0.00.00.1-0.30.2-0.10.20.2-0.1-0.2-0.10.2
Bone: elastic work0.00.00.2-0.20.1-0.40.10.10.1-0.40.00.0
Bone: endosteal estimation1.74.25.22.3-2.22.1-2.1-2.11.41.8-2.1-2.1
Bone: endosteal perimeter1.63.94.92.2-2.11.9-2.1-2.11.41.7-1.9-2.2
Epididymis fat weight0.10.30.50.7-0.50.7-0.5-0.5-0.20.60.3-0.5
Delta time in closed arm before/after self-admin5.04.710.42.0-2.01.6-2.0-2.03.22.0-2.3-2.0
Delta time in open arm before/after self-admin0.00.10.4-0.10.10.10.10.1-0.60.10.20.1
Diff in mean of infusions in LGA sessions0.30.51.60.8-0.60.1-0.6-0.51.30.4-0.7-0.7
Delay discount exponential model param0.40.50.80.8-0.80.5-0.9-0.90.70.7-0.4-0.9
Extinction: sum of active levers before priming0.50.70.90.9-0.90.9-0.8-0.80.90.8-0.9-0.7
Active lever presses in extinction session 60.20.21.1-0.20.2-0.60.10.10.2-1.0-0.4-0.0
Bone: final force1.21.92.6-1.31.3-1.01.41.4-1.6-1.31.61.4
Bone: final moment1.01.62.2-1.21.2-0.91.31.3-1.5-1.21.51.3
Food consumed during 24 hour testing period0.51.01.61.0-1.11.3-1.0-1.00.51.1-0.9-0.9
Glucose0.91.54.1-1.00.9-0.51.01.0-2.0-1.01.71.1
Heart weight3.04.85.42.3-2.32.2-2.3-2.31.92.0-2.1-2.3
Delay discount hyperbolic model param0.40.50.70.7-0.80.5-0.8-0.80.80.6-0.4-0.8
Intermittent access intake day 1-15 change0.10.62.30.8-0.5-0.2-0.6-0.61.50.5-0.7-0.7
Intermittent access intake escalation0.10.61.90.8-0.5-0.4-0.6-0.51.40.6-0.7-0.7
Intermittent access intake escalation 20.71.13.21.0-0.90.0-0.9-0.91.81.1-1.2-1.0
Intermitt. access day 1 inactive lever presses0.10.83.0-0.50.7-1.70.60.61.2-1.10.10.3
Intermitt. access day 15 inactive lever presses0.21.33.2-1.21.1-1.81.01.00.8-1.50.40.9
Intermitt. access escalation Index0.51.73.81.1-1.21.7-1.1-1.10.72.0-1.4-0.9
Intermittent access day 1 total infusions0.00.10.40.1-0.00.50.00.0-0.6-0.10.40.0
Intermittent access day 15 total infusions0.10.30.50.7-0.50.2-0.5-0.50.70.4-0.3-0.6
Intermittent access terminal intake (last 3 days)0.00.00.20.3-0.1-0.3-0.1-0.10.4-0.10.1-0.2
Intermittent access total infusions0.10.10.30.5-0.40.4-0.4-0.40.10.10.1-0.4
Intermittent access day 1 locomotion0.10.30.9-0.30.30.10.40.4-0.9-0.60.70.4
Intermittent access day 15 total locomotion0.20.60.7-0.80.8-0.50.80.8-0.8-0.80.80.8
Intermittent access total locomotion1.01.21.6-1.11.1-0.81.11.2-1.2-1.31.21.1
Intermittent access standard deviation0.10.31.3-0.00.3-1.20.10.21.0-0.80.1-0.1
Left kidney weight0.75.59.42.3-2.31.6-2.4-2.43.12.1-2.4-2.4
Right kidney weight0.10.82.70.7-0.70.1-0.8-0.81.60.7-1.0-0.8
Cocaine induced anxiety2.15.79.52.4-2.31.6-2.3-2.33.11.8-3.0-2.3
Post-drug Anxiety1.41.63.21.3-1.20.7-1.2-1.11.71.1-1.8-1.2
Baseline Anxiety2.74.610.5-2.12.0-1.12.12.1-3.2-1.12.42.2
Tail length1.05.16.82.4-2.41.5-2.5-2.52.51.3-2.4-2.6
Length with tail4.218.822.14.6-4.53.5-4.6-4.64.43.5-4.3-4.7
Length without tail1.910.011.23.3-3.43.3-3.3-3.32.63.1-2.9-3.2
Times rat made contact with spout1.01.11.6-1.31.1-0.91.11.1-0.8-1.10.91.2
Lifetime Intake0.00.10.20.4-0.20.1-0.2-0.20.0-0.10.2-0.4
Liver weight, left0.10.20.30.5-0.50.4-0.5-0.50.40.6-0.3-0.5
Liver weight, right0.30.61.5-0.70.8-1.20.70.70.0-1.10.40.6
Locomotor activity0.61.01.3-1.01.0-0.81.01.0-1.2-0.81.11.0
Locomotor testing distance1.74.14.9-2.02.1-1.92.22.2-2.2-1.71.82.1
Locomotor testing rearing2.17.811.7-2.92.9-3.42.82.8-2.1-3.32.02.6
Locomotion in novel chamber5.16.910.7-2.92.5-2.02.42.3-3.3-2.92.62.4
Locomotion in novel chamber post-restriction0.10.30.7-0.50.5-0.80.50.5-0.3-0.70.20.4
Fecal boli incidents, locomotor time 10.10.20.40.3-0.40.4-0.4-0.40.70.1-0.5-0.4
Change in fecal boli incidents, locomotor task0.40.51.5-0.50.6-0.20.60.7-1.2-0.30.70.7
Time >=10cm from walls, locomotor time 10.70.92.6-0.80.9-0.10.90.9-1.6-0.81.00.9
Bouts of movement, locomotor time 10.81.02.80.9-0.80.5-0.8-0.81.71.0-1.2-0.8
Total resting periods, locomotor time 11.01.22.61.1-1.00.7-0.9-0.91.61.3-1.2-0.9
Rest time, locomotor task time 10.20.32.10.2-0.2-0.5-0.2-0.21.50.2-0.5-0.2
Distance moved, locomotor task time 10.20.53.1-0.30.30.30.40.3-1.8-0.31.10.3
Vertical activity count, locomotor time 10.00.31.30.3-0.31.0-0.3-0.2-1.10.20.2-0.3
Time >=10cm from walls, locomotor time 21.23.413.7-1.51.4-0.11.51.5-3.7-1.32.01.5
Bouts of movement, locomotor time 20.00.10.2-0.20.3-0.40.30.30.4-0.3-0.10.2
Total resting periods, locomotor time 20.00.10.70.10.0-0.2-0.00.00.8-0.0-0.4-0.1
Rest time, locomotor task time 20.91.63.91.1-1.20.8-1.2-1.22.00.8-1.5-1.2
Distance moved, locomotor task time 20.10.21.1-0.10.1-0.00.10.1-1.0-0.30.50.0
Vertical activity count, locomotor time 20.00.10.20.3-0.30.5-0.2-0.2-0.40.2-0.2-0.2
Light reinforcement 10.62.55.0-1.51.7-2.21.61.6-0.7-2.00.91.4
Light reinforcement 20.40.92.2-0.91.0-1.50.90.9-0.1-1.20.70.8
Bone: marrow area1.64.05.02.2-2.12.0-2.1-2.11.41.7-2.0-2.1
Bone: maximum diameter0.00.00.20.1-0.00.1-0.00.0-0.3-0.00.4-0.0
Bone: maximum force0.00.00.10.00.10.00.10.1-0.4-0.10.40.1
Bone: maximum moment0.00.00.10.1-0.00.20.00.0-0.30.10.20.0
Mean time between licks in bursts0.42.42.61.6-1.61.3-1.6-1.61.61.5-1.5-1.6
Mean num. licks in bursts0.00.10.1-0.10.1-0.40.00.10.2-0.4-0.4-0.0
Cd content in liver1.61.82.51.5-1.31.1-1.3-1.31.31.3-1.6-1.3
Co content in liver2.22.62.91.7-1.71.5-1.7-1.71.41.7-1.6-1.7
Cu content in liver0.60.71.40.7-0.7-0.2-0.9-0.91.2-0.0-0.9-1.0
Fe content in liver1.72.12.61.5-1.61.3-1.6-1.61.21.0-1.4-1.6
K content in liver0.20.20.6-0.40.3-0.60.20.2-0.1-0.80.30.2
Mg content in liver0.20.20.6-0.60.5-0.50.40.4-0.2-0.70.40.4
Mn content in liver0.30.31.1-0.40.4-1.00.30.3-0.1-1.00.30.2
Na content in liver0.20.20.3-0.50.5-0.40.40.4-0.3-0.60.50.5
Rb content in liver1.82.14.3-1.41.4-1.81.31.3-0.9-2.11.11.2
Se content in liver4.25.08.0-2.22.2-2.82.12.1-1.5-2.82.01.9
Sr content in liver1.10.91.21.0-1.00.8-1.0-1.01.10.7-0.9-1.0
Zn content in liver1.72.04.3-1.41.5-2.11.41.4-0.5-1.71.11.2
Bone: minimum diameter0.40.71.11.0-1.00.9-1.0-0.90.10.5-0.6-1.0
Time in familiar zone, hab. session 10.40.51.1-0.60.6-0.40.70.7-0.9-0.51.00.6
Time in novel zone, hab. session 10.50.61.0-0.80.8-1.00.80.8-0.3-0.90.30.9
Total zone transitions, hab. session 12.13.03.31.8-1.81.6-1.8-1.81.61.8-1.5-1.8
Total locomotion distance, hab. session 10.00.10.10.2-0.20.1-0.2-0.20.20.3-0.3-0.2
Locomotion velocity, hab. session 10.60.91.11.0-1.00.9-1.0-0.90.81.0-1.0-1.0
Time in familiar zone, hab. session 20.50.50.8-0.60.7-0.90.70.7-0.6-0.80.60.6
Time in novel zone, hab. session 20.00.10.1-0.20.2-0.30.20.20.3-0.20.00.2
Total zone transitions, hab. session 20.60.81.01.0-0.90.7-0.9-0.90.80.7-0.8-1.0
Total locomotion distance, hab. session 20.20.20.60.5-0.40.2-0.4-0.40.50.5-0.7-0.4
Locomotion velocity, hab. session 20.40.50.70.8-0.70.6-0.7-0.70.50.8-0.8-0.7
Novel to familiar place preference ratio1.31.62.91.2-1.31.7-1.2-1.30.71.6-1.2-1.1
Novelty place preference0.91.22.71.0-1.01.6-1.0-1.00.31.5-0.8-0.8
Time in novel zone, NPP test0.40.41.40.5-0.51.2-0.5-0.5-0.21.1-0.4-0.3
Total zone transitions, NPP test0.20.30.50.7-0.70.4-0.7-0.70.40.4-0.3-0.7
Total locomotion distance, NPP test0.00.00.2-0.00.1-0.40.00.00.2-0.2-0.1-0.0
Locomotion velocity, NPP test0.30.40.60.6-0.60.3-0.7-0.60.80.5-0.7-0.7
Intraocular pressure1.62.64.41.7-1.61.9-1.5-1.51.12.1-1.5-1.4
Delta distance traveled before/after self-admin1.01.12.21.0-0.90.8-0.9-0.91.51.1-1.2-0.8
Delta ambulatory time before/after self-admin0.50.82.80.8-0.70.5-0.6-0.61.71.0-1.1-0.4
Parametrial fat weight0.30.61.0-0.70.9-1.00.90.9-0.4-0.80.60.8
Pavlov. Cond. lever latency2.63.34.41.8-1.92.1-1.9-1.91.11.9-1.8-1.8
Pavlov. Cond. magazine entry latency9.812.613.6-3.73.7-3.63.63.6-2.9-3.53.63.5
Pavlov. Cond. change in total contacts9.09.711.2-3.33.3-3.33.23.2-2.3-3.13.13.1
Pavlov. Cond. index score9.111.612.6-3.53.5-3.63.53.5-2.7-3.53.43.4
Pavlov. Cond. latency score7.19.110.1-3.13.1-3.23.13.1-2.3-3.03.03.0
Pavlov. Cond. lever contacts3.33.94.9-2.02.1-2.22.02.0-1.3-2.02.01.9
Pavlov. Cond. magazine entry number14.017.819.44.4-4.44.3-4.3-4.33.54.2-4.1-4.3
Pavlov. Cond. intertrial magazine entries1.31.61.81.3-1.31.2-1.3-1.31.21.1-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.10.713.314.5-3.83.8-3.83.73.8-2.9-3.73.73.6
Pavlov. Cond. response bias10.713.314.6-3.83.8-3.83.73.7-2.9-3.73.73.6
Pavlov. Cond. lever latency0.20.30.50.7-0.60.6-0.6-0.60.30.5-0.5-0.6
Pavlov. Cond. magazine entry latency0.10.10.30.0-0.10.5-0.1-0.1-0.10.50.4-0.0
Pavlov. Cond. change in total contacts0.30.61.1-0.80.8-0.70.80.8-0.6-0.81.10.7
Pavlov. Cond. index score0.10.20.4-0.60.5-0.30.50.4-0.3-0.20.60.5
Pavlov. Cond. latency score0.10.20.4-0.50.4-0.20.40.4-0.4-0.10.60.5
Pavlov. Cond. lever contacts0.40.60.8-0.90.8-0.70.80.8-0.5-0.70.70.8
Pavlov. Cond. magazine entry number0.20.20.70.5-0.50.4-0.5-0.40.20.2-0.9-0.5
Pavlov. Cond. intertrial magazine entries1.22.63.31.7-1.61.8-1.6-1.61.21.8-1.6-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.40.3-0.20.30.3-0.1-0.10.50.3
Pavlov. Cond. response bias0.81.01.4-1.21.1-0.91.11.0-0.7-0.91.21.1
Time in closed arm before self-admin1.22.14.9-1.31.5-2.21.41.4-0.8-1.51.41.3
Time in closed arm after self-admin0.50.62.30.6-0.6-0.1-0.7-0.61.50.4-0.7-0.7
Time in open arm before self-admin2.02.44.41.5-1.72.1-1.7-1.70.81.2-1.5-1.6
Time in open arm after self-admin0.30.30.80.5-0.60.9-0.6-0.6-0.10.5-0.5-0.6
Bone: periosteal estimation0.10.30.60.7-0.70.7-0.6-0.60.10.5-0.4-0.6
Bone: periosteal perimeter0.61.11.41.2-1.21.1-1.1-1.10.71.1-0.6-1.2
Bone: post-yield work0.81.42.11.2-1.21.0-1.1-1.11.41.4-1.0-1.1
Progressive ratio test 1 active lever presses0.30.51.8-0.40.5-0.00.60.6-1.4-0.60.90.7
Progressive ratio test 1 breakpoint0.30.41.6-0.30.50.00.60.6-1.2-0.50.80.6
Progressive ratio test 1 inactive lever presses0.00.10.60.10.1-0.50.00.10.8-0.4-0.1-0.1
Progressive ratio test 2 active lever presses0.60.92.3-0.70.7-0.50.70.7-1.4-1.01.50.7
Progressive ratio test 2 breakpoint0.81.02.6-0.80.8-0.50.80.8-1.5-1.11.60.7
Progressive ratio test 2 inactive lever presses0.00.10.30.1-0.2-0.1-0.3-0.30.5-0.50.1-0.4
Incentive Sensitization - Responses0.51.32.9-1.01.0-0.70.90.9-1.5-1.31.70.8
Incentive Sensitization - Breakpoint0.51.12.6-1.00.9-0.60.80.8-1.3-1.21.60.7
Sum of active levers in priming session hrs 5-60.20.20.7-0.40.4-0.40.40.4-0.4-0.80.40.4
Progressive ratio0.00.10.20.1-0.00.0-0.1-0.1-0.4-0.50.4-0.3
Food seeking constrained by brief footshock0.40.51.1-0.60.7-1.00.70.7-0.2-0.90.50.7
Seeking ratio, punishment vs. effort0.10.20.5-0.40.4-0.30.50.50.10.2-0.10.7
Retroperitoneal fat weight0.10.30.6-0.30.5-0.70.60.6-0.5-0.80.40.5
Reaction time number correct0.31.23.21.1-1.11.8-1.1-1.1-0.21.3-0.4-1.0
Reaction time mean minus median0.00.20.70.4-0.40.2-0.3-0.30.70.8-0.6-0.2
Reaction time mean minus median AUC0.00.20.5-0.50.5-0.30.60.6-0.20.10.40.7
Reaction time num false alarms0.61.01.6-0.90.9-0.70.90.9-1.3-0.91.20.9
Reaction time num false alarms AUC0.30.61.2-0.70.8-0.50.80.8-1.0-0.61.10.8
Reaction time trials correct on left0.31.23.21.1-1.11.8-1.1-1.1-0.21.3-0.4-1.0
Reaction time trials on left0.31.13.11.0-1.11.8-1.0-1.0-0.11.2-0.4-1.0
Reaction time mean0.10.10.7-0.30.2-0.50.20.10.9-0.0-0.30.2
Reaction time mean AUC0.10.21.0-0.20.1-0.50.10.01.0-0.0-0.40.1
Median of all reaction times0.20.40.9-0.80.6-0.90.60.50.5-0.60.20.6
Reaction time omissions0.20.30.9-0.50.6-0.90.60.60.1-0.30.40.6
Reaction time false alarm rate1.11.51.8-1.21.3-1.31.31.3-0.9-1.11.21.2
Reaction time premature initiation rate0.10.20.3-0.30.5-0.30.50.5-0.3-0.20.20.5
Reaction time premature initiations0.10.20.80.5-0.40.9-0.4-0.3-0.10.7-0.4-0.3
Std. dev. reaction times0.00.10.4-0.10.1-0.40.10.10.70.3-0.20.2
Reaction time trials completed0.31.13.11.0-1.11.8-1.0-1.0-0.11.2-0.4-1.0
Reaction time trials AUC0.31.03.10.9-1.01.8-0.9-0.9-0.31.2-0.3-0.9
Run reversals in cocaine runway, females1.51.63.01.3-1.41.7-1.3-1.30.91.3-1.0-1.2
Run reversals in cocaine runway, males0.30.30.7-0.70.5-0.10.50.5-0.8-0.70.30.6
Latency to leave start box in cocaine runway1.72.33.41.6-1.71.6-1.7-1.71.11.3-0.9-1.8
Latency to leave start box in cocaine runway, F2.43.05.41.8-1.92.3-1.9-1.90.51.8-0.8-1.9
Latency to leave start box in cocaine runway, M0.40.41.70.2-0.2-0.7-0.4-0.41.3-0.5-0.6-0.6
Std. dev. time between licks in bursts0.20.41.30.4-0.50.1-0.6-0.61.10.5-0.8-0.5
Total sessions with >9 infusions0.00.00.10.10.0-0.30.00.0-0.2-0.30.4-0.1
Short access day 1 total inactive lever presses0.51.12.9-0.91.1-1.71.01.00.0-1.10.90.7
Short access day 10 total inactive lever presses0.21.35.90.9-0.8-0.1-0.9-0.92.40.5-1.3-1.0
Short access day 1 total infusions0.10.10.6-0.20.3-0.50.20.2-0.2-0.80.50.0
Short access day 10 total infusions0.20.30.5-0.40.5-0.40.50.5-0.6-0.60.70.4
Short access total infusions0.00.00.20.10.0-0.2-0.0-0.0-0.2-0.50.3-0.1
Short access day 1 locomotion0.50.92.0-0.80.9-1.40.90.9-0.1-1.40.80.7
Short access day 10 total locomotion0.83.23.8-1.81.8-1.61.91.9-1.7-1.91.61.9
Short access total locomotion0.20.30.9-0.40.5-0.60.50.5-0.5-0.90.60.4
One hour access (0.3 mA shock)0.20.30.80.5-0.30.8-0.2-0.1-0.90.60.5-0.1
Compulsive drug intake0.10.21.0-0.20.20.30.40.3-1.00.00.40.5
One hour access (shock baseline)0.10.20.40.6-0.50.4-0.5-0.40.30.3-0.1-0.6
Social response proportion0.00.00.1-0.00.0-0.30.00.00.10.10.10.0
Social responses0.20.31.7-0.30.4-1.30.30.30.2-0.80.20.1
Social time0.00.00.10.0-0.0-0.1-0.1-0.10.10.1-0.3-0.1
Soleus weight0.41.22.0-1.11.1-0.41.21.2-1.2-0.51.31.4
Bone: stiffness0.00.10.30.00.00.20.10.1-0.5-0.00.50.1
Tibialis anterior weight1.34.35.52.0-2.12.2-2.1-2.12.02.3-2.0-1.9
Time to tail flick, vehicle, before self-admin0.20.20.7-0.40.5-0.80.50.50.2-0.00.10.5
Time to tail flick, vehicle, after self-admin0.00.10.2-0.30.20.20.30.2-0.5-0.0-0.00.3
Time to tail flick, test, before self-admin0.60.71.50.9-0.80.9-0.7-0.70.61.2-1.1-0.6
Time to tail flick, test, after self-admin0.20.20.8-0.30.4-0.90.30.30.4-0.7-0.10.3
Delta time to tail flick, vehicle, before/after SA0.50.51.7-0.70.60.20.60.6-1.3-0.70.70.7
Delta time to tail flick, test, before/after SA2.22.75.0-1.71.6-1.71.51.5-1.4-2.21.61.4
Tibia length0.71.93.21.4-1.41.8-1.4-1.40.71.7-1.2-1.2
Ambulatory time before self-admin0.20.51.10.8-0.80.5-0.9-0.80.50.2-0.5-1.0
Ambulatory time after self-admin2.13.47.62.0-1.80.9-1.8-1.72.81.4-1.9-1.9
Bone: tissue strength0.50.61.50.7-0.71.0-0.6-0.70.61.2-0.5-0.5
Total heroin consumption0.80.92.2-1.00.9-1.30.80.8-0.7-1.50.70.7
Bone: trabecular number4.68.611.6-3.03.1-3.43.03.0-2.1-3.02.62.9
Bone: trabecular spacing1.01.52.81.3-1.31.7-1.2-1.20.51.5-0.9-1.1
Bone: trabecular thickness0.00.10.2-0.20.2-0.50.20.10.3-0.10.20.1
Bone: trabecular tissue density0.00.00.00.1-0.10.2-0.1-0.1-0.0-0.0-0.2-0.0
Water consumed over 24 hours0.00.10.30.1-0.10.5-0.1-0.1-0.40.4-0.10.0
Number of responses in last shaping day0.20.31.30.1-0.1-0.7-0.2-0.21.1-0.4-0.4-0.3