Hub : Genes

Camp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Camp 0.14 0.08 0.0e+00 0.17 0.16 0.16 0.16 6.9e-19 6.0e-18 9.6e-19 1.1e-18
2 Brain gene expression Camp 0.15 0.08 0.0e+00 0.2 0.2 0.2 0.2 5.6e-18 8.7e-19 1.9e-18 2.8e-18
3 pVTA gene expression Camp 0.75 0.14 3.3e-15 0.26 0.26 0.28 0.26 1.7e-11 2.0e-11 1.1e-12 7.9e-12
4 PL gene expression Camp 0.09 0.06 1.5e-10 0.08 0.08 0.08 0.08 6.7e-09 1.5e-09 4.2e-09 5.1e-09
5 RMTg gene expression Camp 0.56 0.2 9.6e-10 0.22 0.26 0.24 0.25 1.4e-06 1.4e-07 5.2e-07 2.3e-07
6 BLA gene expression Camp 0.21 0.12 2.1e-11 0.17 0.16 0.18 0.19 1.5e-09 6.4e-09 4.6e-10 2.0e-10
7 LHb gene expression Camp 0.34 0.17 3.2e-04 0.12 0.11 0.06 0.13 1.0e-03 1.4e-03 2.0e-02 5.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.20.31.7-0.1-0.1-0.20.50.5-0.21.3
Area under the delay curve1.41.52.71.2-1.61.3-1.1-0.9-1.50.6
BMI with tail0.31.12.2-1.51.2-0.80.80.81.00.8
BMI without tail1.63.24.7-2.21.9-1.81.71.81.81.3
Body weight4.920.529.5-5.45.4-4.64.54.34.91.0
Weight adjusted by age0.50.51.0-0.80.9-0.70.30.30.8-1.0
Bone surface0.10.10.20.3-0.30.3-0.2-0.2-0.50.4
Bone volume0.10.10.50.1-0.20.1-0.00.0-0.40.7
Breakpoint value in progressive ratio session0.20.30.5-0.40.2-0.50.40.50.70.7
Number of licking bursts0.70.83.30.6-0.30.6-0.9-1.0-0.2-1.8
Context. condit. distance diff. score0.00.00.0-0.10.0-0.0-0.1-0.10.1-0.2
Locomotion velocity, session 10.10.10.30.1-0.30.2-0.1-0.0-0.30.5
Locomotion distance, session 11.11.42.9-1.30.9-1.01.21.30.81.7
Locomotion velocity, session 20.20.30.40.4-0.50.6-0.6-0.6-0.5-0.1
Locomotion distance, session 20.20.32.00.0-0.30.20.10.2-0.41.4
Locomotion velocity, session 30.50.63.2-0.50.1-0.20.50.7-0.11.8
Locomotion distance, session 31.11.22.00.9-1.31.2-0.9-0.7-1.41.1
Stereotopy head waving bouts, day 30.40.52.9-0.10.5-0.0-0.3-0.40.5-1.7
Stereotopy head waving duration, day 30.30.31.0-0.30.6-0.50.30.20.7-1.0
Locomotion velocity, session 70.40.41.9-0.3-0.0-0.30.60.6-0.11.4
Locomotion distance, session 70.91.22.11.1-1.31.2-0.9-0.8-1.40.7
Stereotopy head waving bouts, day 70.00.00.20.2-0.2-0.00.00.0-0.20.4
Stereotopy head waving duration, day 70.30.40.5-0.60.6-0.70.70.70.60.7
Locomotion velocity, session 80.50.62.5-0.70.3-0.40.60.70.31.6
Locomotion distance, session 80.81.25.8-0.70.2-0.60.81.00.12.4
Degree of sensitization distance0.90.91.2-0.91.0-1.11.00.91.1-0.1
Degree of sensitization stereotypy0.30.31.2-0.20.1-0.40.50.60.01.1
Conditioned locomotion2.32.74.11.9-2.01.6-1.6-1.5-1.90.0
Cocaine response after cond. corrected0.60.62.3-0.40.8-0.50.0-0.11.0-1.5
Cocaine response after cond. not corrected1.51.72.9-1.41.7-1.31.00.91.7-0.8
Cocaine response before conditioning1.41.62.5-1.41.1-1.11.41.40.81.6
Saline control response1.82.33.4-1.31.1-1.51.81.81.11.8
Bone: connectivity density0.30.51.70.6-0.80.30.00.1-0.81.3
Bone: cortical apparent density0.20.20.40.6-0.60.5-0.3-0.3-0.60.2
Bone: cortical area0.71.04.00.5-0.10.7-1.0-1.1-0.2-2.0
Bone: cortical porosity0.20.31.30.2-0.5-0.10.30.3-0.31.1
Bone: cortical porosity0.30.41.30.5-0.80.20.10.1-0.61.1
Bone: cortical thickness0.50.84.3-0.30.70.0-0.3-0.50.6-2.1
Bone: cortical thickness0.00.00.10.00.00.1-0.1-0.2-0.0-0.4
Bone: cortical tissue density0.20.20.40.6-0.60.5-0.3-0.3-0.60.3
Condit. Reinf. active minus inactive responses0.20.21.0-0.20.40.10.1-0.10.2-1.0
Condit. Reinf. active-inactive response ratio0.40.42.0-0.40.7-0.10.2-0.00.5-1.4
Condit. Reinf. active responses0.10.10.60.2-0.00.2-0.3-0.30.0-0.8
Condit. Reinf. inactive responses0.40.40.70.8-0.90.5-0.7-0.6-0.60.3
Incentive salience index mean0.10.10.40.2-0.10.4-0.4-0.4-0.2-0.6
Condit. Reinf. lever presses1.11.51.91.3-1.31.3-1.4-1.3-1.3-0.3
Condit. Reinf. active minus inactive responses1.51.82.9-1.71.6-1.21.41.31.50.4
Condit. Reinf. active-inactive response ratio1.21.22.0-1.41.4-1.01.01.01.30.1
Condit. Reinf. active responses1.41.92.9-1.71.7-1.21.51.41.50.3
Condit. Reinf. inactive responses0.00.00.00.0-0.10.10.0-0.0-0.2-0.0
Condit. Reinf. lever presses1.82.44.1-2.01.9-1.31.61.51.60.5
Condit. Reinf. lever reinforcers received1.52.23.2-1.81.7-1.31.51.41.60.3
Conditioned reinforcement - actives0.20.20.40.5-0.70.6-0.5-0.4-0.40.2
Conditioned reinforcement - inactives1.92.14.81.1-0.81.5-1.6-1.7-0.8-2.2
Conditioned locomotion0.30.31.00.4-0.70.4-0.2-0.1-0.61.0
Patch foraging indifference point 0 sec1.52.43.4-1.51.2-1.71.71.91.31.5
Patch foraging indifference point AUC0.40.52.1-0.3-0.0-0.40.50.70.21.5
Delay disc. indifference point, 0s delay0.00.00.10.2-0.20.1-0.1-0.0-0.00.3
Delay disc. indifference point, 16s delay0.70.71.20.9-1.10.8-0.7-0.6-1.10.5
Delay disc. indifference point, 2s delay0.10.20.30.3-0.60.5-0.4-0.3-0.50.2
Delay disc. indifference point, 24s delay0.60.61.10.8-1.00.8-0.7-0.6-1.00.4
Delay disc. indifference point, 4s delay1.31.32.11.2-1.51.2-1.3-1.1-1.2-0.1
Delay disc. indifference point, 8s delay1.61.62.71.3-1.61.3-1.2-1.0-1.60.5
Indifference point function ln k0.30.41.20.5-0.50.8-0.6-0.7-1.10.1
Indifference point function log k0.30.41.20.5-0.50.8-0.6-0.7-1.10.1
Patch foraging total patch changes 0 sec1.52.43.2-1.51.4-1.71.71.81.41.1
Patch foraging total patch changes 12 sec1.01.31.7-1.11.1-1.31.31.31.20.6
Patch foraging total patch changes 18 sec2.32.93.9-1.61.5-1.82.01.91.71.2
Patch foraging total patch changes 24 sec2.42.93.6-1.91.9-1.71.91.71.80.6
Patch foraging total patch changes 6 sec0.60.92.6-0.50.3-0.81.01.10.41.6
Patch foraging time to switch 0 sec0.40.52.20.5-0.20.5-0.7-0.8-0.2-1.5
Patch foraging water rate 0 sec0.10.20.2-0.40.5-0.50.50.40.40.1
Patch foraging water rate 12 sec0.10.20.2-0.40.5-0.40.40.40.40.2
Patch foraging water rate 18 sec0.10.10.3-0.10.20.1-0.3-0.20.0-0.6
Patch foraging water rate 24 sec0.50.71.1-0.91.1-0.90.80.81.0-0.0
Patch foraging water rate 6 sec0.20.30.5-0.60.5-0.40.70.50.30.7
Seeking ratio, delayed vs. immediate footshock1.72.03.61.7-1.91.2-1.4-1.1-1.40.5
Distance traveled before self-admin0.30.31.50.30.10.4-0.4-0.6-0.4-1.2
Distance traveled after self-admin0.40.50.60.5-0.50.7-0.7-0.7-0.8-0.8
Extensor digitorum longus weight0.20.81.40.7-0.60.9-1.0-1.0-0.6-1.2
Bone: elastic displacement0.20.21.0-0.20.40.0-0.0-0.20.3-1.0
Bone: elastic work0.30.40.8-0.80.9-0.40.40.30.7-0.6
Bone: endosteal estimation0.10.20.6-0.20.0-0.30.40.50.10.8
Bone: endosteal perimeter0.91.92.51.5-1.61.5-1.4-1.3-1.6-0.2
Epididymis fat weight0.20.40.7-0.80.8-0.50.60.50.80.1
Delta time in closed arm before/after self-admin0.30.30.60.7-0.60.5-0.3-0.5-0.40.3
Delta time in open arm before/after self-admin0.20.20.3-0.50.4-0.50.50.60.00.4
Diff in mean of infusions in LGA sessions0.50.62.8-0.10.4-0.0-0.4-0.40.7-1.7
Delay discount exponential model param1.71.83.0-1.41.7-1.41.31.11.6-0.4
Extinction: sum of active levers before priming0.20.20.8-0.1-0.1-0.40.20.40.30.9
Active lever presses in extinction session 60.60.61.8-0.70.3-0.60.80.90.31.3
Bone: final force0.71.22.1-1.21.4-1.00.70.61.4-0.8
Bone: final moment0.91.52.7-1.41.6-1.10.80.71.6-0.9
Food consumed during 24 hour testing period1.11.42.0-1.41.4-1.11.21.11.20.2
Glucose0.60.92.4-0.80.5-0.71.01.00.51.5
Heart weight2.12.95.2-1.82.3-1.71.41.22.2-1.0
Delay discount hyperbolic model param1.61.73.0-1.31.7-1.41.31.11.5-0.5
Intermittent access intake day 1-15 change1.41.43.90.9-0.51.1-1.2-1.3-0.8-2.0
Intermittent access intake escalation1.31.23.00.9-0.51.1-1.1-1.2-0.9-1.7
Intermittent access intake escalation 20.70.73.40.20.30.5-0.5-0.7-0.3-1.8
Intermitt. access day 1 inactive lever presses0.00.00.0-0.20.1-0.00.00.00.1-0.1
Intermitt. access day 15 inactive lever presses0.90.92.20.7-0.60.9-1.1-1.1-0.5-1.5
Intermitt. access escalation Index0.10.10.6-0.1-0.1-0.20.20.3-0.00.8
Intermittent access day 1 total infusions0.00.00.1-0.0-0.2-0.1-0.10.10.10.3
Intermittent access day 15 total infusions0.40.50.70.5-0.50.7-0.8-0.7-0.7-0.8
Intermittent access terminal intake (last 3 days)0.10.10.20.3-0.40.4-0.5-0.4-0.4-0.3
Intermittent access total infusions0.30.40.60.5-0.70.7-0.7-0.6-0.6-0.3
Intermittent access day 1 locomotion0.10.10.20.2-0.40.2-0.2-0.1-0.10.4
Intermittent access day 15 total locomotion0.80.91.61.0-1.11.0-0.7-0.7-1.30.6
Intermittent access total locomotion0.91.01.71.1-1.31.0-0.8-0.7-1.30.7
Intermittent access standard deviation0.60.63.6-0.30.70.1-0.2-0.30.3-1.9
Left kidney weight1.23.46.8-1.91.4-1.61.82.01.32.6
Right kidney weight0.51.55.3-1.00.5-0.91.11.30.32.3
Cocaine induced anxiety0.20.20.90.1-0.20.1-0.7-0.40.0-0.9
Post-drug Anxiety0.10.10.30.1-0.20.1-0.4-0.30.1-0.5
Baseline Anxiety0.60.71.21.0-0.80.9-0.6-0.7-1.10.1
Tail length5.616.920.7-4.44.5-4.64.34.34.41.4
Length with tail7.427.035.7-5.86.0-5.65.45.25.61.2
Length without tail5.010.915.8-3.84.0-3.43.43.13.70.2
Times rat made contact with spout0.60.71.0-1.01.0-0.80.80.70.9-0.3
Lifetime Intake0.30.30.50.6-0.70.7-0.6-0.5-0.7-0.0
Liver weight, left0.20.41.3-0.2-0.0-0.50.60.70.31.1
Liver weight, right1.62.73.5-1.51.3-1.71.81.91.51.8
Locomotor activity4.77.59.5-3.03.0-3.12.82.82.91.0
Locomotor testing distance4.16.88.4-2.92.7-2.92.72.72.71.2
Locomotor testing rearing0.00.10.1-0.20.2-0.40.20.20.4-0.2
Locomotion in novel chamber0.20.20.70.4-0.20.4-0.5-0.5-0.4-0.8
Locomotion in novel chamber post-restriction0.60.71.2-0.70.8-0.81.11.00.51.0
Fecal boli incidents, locomotor time 10.50.51.1-0.60.8-1.00.50.61.1-0.1
Change in fecal boli incidents, locomotor task0.10.10.2-0.2-0.10.30.20.0-0.20.4
Time >=10cm from walls, locomotor time 10.30.30.70.6-0.60.5-0.1-0.3-0.80.7
Bouts of movement, locomotor time 10.10.10.3-0.30.2-0.40.10.20.5-0.1
Total resting periods, locomotor time 10.10.10.3-0.20.2-0.30.10.10.5-0.1
Rest time, locomotor task time 10.40.40.80.9-0.90.5-0.7-0.6-0.40.2
Distance moved, locomotor task time 11.11.22.3-1.31.5-1.01.10.91.0-0.4
Vertical activity count, locomotor time 10.80.81.2-1.01.1-1.10.90.90.80.0
Time >=10cm from walls, locomotor time 21.11.21.5-1.01.2-1.21.21.11.10.5
Bouts of movement, locomotor time 20.20.20.60.1-0.00.5-0.4-0.4-0.1-0.8
Total resting periods, locomotor time 20.30.30.60.4-0.40.8-0.6-0.6-0.4-0.7
Rest time, locomotor task time 20.00.10.10.2-0.4-0.1-0.2-0.00.10.4
Distance moved, locomotor task time 20.70.81.8-1.01.3-0.61.00.70.8-0.4
Vertical activity count, locomotor time 20.00.10.1-0.20.4-0.20.30.20.0-0.1
Light reinforcement 10.61.11.7-1.11.1-1.31.01.11.20.5
Light reinforcement 20.30.42.00.4-0.60.2-0.10.0-0.71.4
Bone: marrow area0.10.20.7-0.20.1-0.40.50.50.10.8
Bone: maximum diameter0.61.02.30.8-0.50.9-1.2-1.2-0.6-1.5
Bone: maximum force0.50.91.4-1.01.2-1.00.80.71.1-0.4
Bone: maximum moment0.61.01.7-1.11.3-1.00.80.71.2-0.5
Mean time between licks in bursts1.21.72.21.4-1.31.5-1.3-1.4-1.4-0.5
Mean num. licks in bursts1.31.63.2-1.20.8-1.11.41.40.71.8
Cd content in liver2.02.23.6-1.41.8-1.61.31.21.9-1.0
Co content in liver0.20.21.10.10.00.4-0.4-0.5-0.2-1.0
Cu content in liver3.84.66.0-2.22.1-2.52.32.32.41.1
Fe content in liver1.51.83.0-1.11.6-1.41.21.11.7-0.9
K content in liver1.21.21.6-1.00.9-1.21.01.11.11.3
Mg content in liver0.20.20.9-0.2-0.0-0.20.10.20.11.0
Mn content in liver0.91.02.9-1.00.6-0.81.11.10.41.7
Na content in liver0.40.40.7-0.50.5-0.80.80.80.60.5
Rb content in liver0.91.12.5-0.61.1-0.90.70.51.4-1.6
Se content in liver0.10.10.2-0.10.3-0.40.30.30.30.4
Sr content in liver0.10.10.7-0.30.0-0.00.10.2-0.10.8
Zn content in liver4.34.85.9-2.32.2-2.42.32.32.31.2
Bone: minimum diameter0.40.81.00.9-0.91.0-1.0-1.0-0.9-0.6
Time in familiar zone, hab. session 11.91.82.81.5-1.11.2-1.4-1.5-0.9-1.7
Time in novel zone, hab. session 10.70.71.2-1.10.9-0.80.90.90.60.7
Total zone transitions, hab. session 10.81.13.4-1.00.7-0.81.01.10.41.8
Total locomotion distance, hab. session 10.40.51.3-0.70.5-0.60.70.80.51.1
Locomotion velocity, hab. session 10.50.72.0-0.80.5-0.60.80.90.51.4
Time in familiar zone, hab. session 21.11.12.21.0-0.71.0-1.1-1.2-0.6-1.5
Time in novel zone, hab. session 20.20.20.5-0.30.1-0.30.40.50.00.7
Total zone transitions, hab. session 20.10.20.8-0.40.2-0.10.20.30.00.9
Total locomotion distance, hab. session 20.50.61.3-0.80.6-0.70.70.80.71.2
Locomotion velocity, hab. session 20.40.61.6-0.70.5-0.60.70.80.61.3
Novel to familiar place preference ratio2.12.17.8-0.70.4-1.21.51.60.42.8
Novelty place preference2.22.38.4-0.70.4-1.21.61.70.42.9
Time in novel zone, NPP test2.12.27.0-0.80.5-1.31.61.70.62.6
Total zone transitions, NPP test2.94.18.4-2.11.5-1.82.02.21.32.9
Total locomotion distance, NPP test1.21.72.0-1.41.2-1.31.31.41.21.4
Locomotion velocity, NPP test1.42.03.1-1.51.2-1.31.41.51.11.8
Intraocular pressure0.81.11.7-0.81.0-1.21.31.21.20.4
Delta distance traveled before/after self-admin0.10.10.2-0.1-0.40.1-0.20.1-0.20.5
Delta ambulatory time before/after self-admin0.50.50.8-0.90.4-0.70.60.80.60.8
Parametrial fat weight1.12.22.7-1.61.5-1.51.61.71.31.2
Pavlov. Cond. lever latency4.45.56.9-2.42.5-2.62.62.52.40.9
Pavlov. Cond. magazine entry latency6.07.89.72.9-2.73.0-3.1-3.1-2.7-1.8
Pavlov. Cond. change in total contacts1.82.02.51.4-1.31.5-1.5-1.6-1.2-1.3
Pavlov. Cond. index score5.97.59.42.8-2.73.0-3.1-3.0-2.6-1.8
Pavlov. Cond. latency score5.67.18.92.8-2.72.9-3.0-2.9-2.6-1.5
Pavlov. Cond. lever contacts2.42.83.61.7-1.71.9-1.9-1.8-1.7-0.7
Pavlov. Cond. magazine entry number6.98.610.4-3.12.9-3.13.23.22.81.8
Pavlov. Cond. intertrial magazine entries0.30.30.4-0.50.5-0.70.60.60.60.4
Pavlov. Cond. lever-magazine prob. diff.5.66.98.92.6-2.42.8-3.0-3.0-2.4-2.1
Pavlov. Cond. response bias6.68.010.02.9-2.73.1-3.2-3.2-2.6-1.9
Pavlov. Cond. lever latency0.20.30.60.8-0.70.3-0.5-0.5-0.5-0.3
Pavlov. Cond. magazine entry latency0.10.20.30.3-0.30.5-0.5-0.5-0.4-0.1
Pavlov. Cond. change in total contacts1.62.23.3-1.81.8-1.41.41.41.70.2
Pavlov. Cond. index score0.00.00.1-0.30.30.00.00.00.2-0.1
Pavlov. Cond. latency score0.00.00.1-0.30.30.1-0.0-0.00.2-0.0
Pavlov. Cond. lever contacts0.71.01.5-1.21.1-0.91.01.01.00.8
Pavlov. Cond. magazine entry number0.40.50.7-0.60.6-0.80.80.80.60.3
Pavlov. Cond. intertrial magazine entries0.40.60.70.8-0.70.7-0.7-0.7-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.30.30.1-0.0-0.00.2-0.1
Pavlov. Cond. response bias0.00.00.1-0.30.20.10.00.00.10.1
Time in closed arm before self-admin1.01.21.9-1.21.4-1.01.21.11.00.0
Time in closed arm after self-admin0.00.00.10.30.10.2-0.0-0.20.1-0.3
Time in open arm before self-admin0.70.71.10.9-1.00.8-1.0-1.0-0.8-0.3
Time in open arm after self-admin0.50.62.20.3-0.80.1-0.00.1-1.01.5
Bone: periosteal estimation0.00.00.2-0.00.10.1-0.2-0.20.0-0.4
Bone: periosteal perimeter1.11.92.41.4-1.31.5-1.5-1.5-1.3-1.0
Bone: post-yield work0.00.00.2-0.20.1-0.20.20.20.10.4
Progressive ratio test 1 active lever presses0.20.20.90.0-0.30.00.10.3-0.11.0
Progressive ratio test 1 breakpoint0.20.20.90.1-0.40.10.10.2-0.11.0
Progressive ratio test 1 inactive lever presses0.50.51.00.6-0.50.8-0.9-0.8-0.3-1.0
Progressive ratio test 2 active lever presses0.60.60.90.7-1.00.9-0.9-0.7-0.9-0.1
Progressive ratio test 2 breakpoint0.40.40.60.6-0.80.7-0.8-0.6-0.7-0.3
Progressive ratio test 2 inactive lever presses2.02.34.41.1-1.11.5-1.8-1.7-1.0-2.1
Incentive Sensitization - Responses1.41.41.91.1-1.11.2-1.4-1.3-1.1-1.0
Incentive Sensitization - Breakpoint1.31.41.91.0-1.11.2-1.4-1.3-1.0-1.1
Sum of active levers in priming session hrs 5-60.80.70.9-0.90.8-0.90.91.00.80.7
Progressive ratio3.43.94.9-2.02.0-2.22.22.11.91.2
Food seeking constrained by brief footshock0.91.11.61.2-0.91.2-0.9-1.1-1.3-0.5
Seeking ratio, punishment vs. effort5.46.68.32.6-2.42.9-2.7-2.8-2.6-1.7
Retroperitoneal fat weight0.41.52.1-1.11.2-1.21.51.40.91.1
Reaction time number correct0.60.91.11.0-0.81.0-0.9-1.0-1.0-0.8
Reaction time mean minus median0.10.20.5-0.50.2-0.40.30.40.40.7
Reaction time mean minus median AUC0.30.40.7-0.70.4-0.60.60.70.60.9
Reaction time num false alarms0.20.30.50.7-0.70.5-0.6-0.5-0.6-0.3
Reaction time num false alarms AUC0.00.10.20.3-0.40.2-0.1-0.1-0.40.1
Reaction time trials correct on left0.60.91.11.0-0.81.0-0.9-1.0-1.0-0.8
Reaction time trials on left0.70.91.11.1-0.81.1-0.9-1.0-1.1-0.8
Reaction time mean0.00.00.10.2-0.10.10.10.1-0.10.4
Reaction time mean AUC0.10.10.30.2-0.20.10.10.1-0.30.6
Median of all reaction times0.00.00.10.3-0.10.20.1-0.0-0.30.2
Reaction time omissions0.20.30.40.7-0.50.5-0.4-0.5-0.4-0.6
Reaction time false alarm rate0.00.00.0-0.0-0.1-0.10.00.1-0.00.2
Reaction time premature initiation rate2.02.73.9-2.01.7-1.71.71.81.70.8
Reaction time premature initiations0.71.11.8-1.31.2-1.01.11.10.90.3
Std. dev. reaction times0.20.30.9-0.30.2-0.30.50.50.21.0
Reaction time trials completed0.70.91.11.1-0.81.1-0.9-1.0-1.1-0.8
Reaction time trials AUC0.81.21.51.2-1.01.2-1.0-1.1-1.2-0.8
Run reversals in cocaine runway, females2.62.53.41.7-1.31.8-1.5-1.8-1.7-1.1
Run reversals in cocaine runway, males0.90.91.4-1.11.1-1.00.60.61.2-0.7
Latency to leave start box in cocaine runway0.60.61.2-0.80.8-0.90.70.71.10.1
Latency to leave start box in cocaine runway, F1.21.32.3-1.21.5-1.10.90.81.5-0.9
Latency to leave start box in cocaine runway, M0.20.21.10.2-0.6-0.0-0.10.2-0.11.1
Std. dev. time between licks in bursts5.36.48.32.5-2.22.6-2.8-2.9-2.2-2.4
Total sessions with >9 infusions0.40.41.50.4-0.20.6-0.7-0.7-0.1-1.2
Short access day 1 total inactive lever presses5.25.87.62.6-2.32.8-2.5-2.6-2.4-1.4
Short access day 10 total inactive lever presses0.60.73.6-0.20.40.0-0.5-0.50.5-1.9
Short access day 1 total infusions1.01.11.41.1-1.11.2-1.1-1.1-0.8-0.6
Short access day 10 total infusions0.10.10.20.3-0.40.4-0.2-0.1-0.40.3
Short access total infusions0.70.71.01.0-1.01.0-0.7-0.7-1.00.3
Short access day 1 locomotion0.00.00.10.0-0.20.2-0.2-0.2-0.1-0.0
Short access day 10 total locomotion0.20.21.1-0.1-0.0-0.00.40.4-0.11.1
Short access total locomotion0.20.21.3-0.1-0.2-0.10.30.40.01.2
One hour access (0.3 mA shock)0.30.30.60.5-0.70.5-0.3-0.3-0.80.6
Compulsive drug intake0.30.31.30.5-0.60.30.0-0.0-0.61.1
One hour access (shock baseline)0.00.00.1-0.1-0.10.1-0.3-0.1-0.0-0.3
Social response proportion0.30.30.6-0.70.8-0.50.80.50.4-0.1
Social responses0.40.60.7-0.90.7-0.80.80.80.70.6
Social time0.70.92.60.7-0.40.7-1.1-1.1-0.7-1.6
Soleus weight3.08.811.7-3.43.4-3.23.02.93.20.8
Bone: stiffness0.10.10.2-0.40.5-0.50.40.40.4-0.0
Tibialis anterior weight0.00.10.3-0.20.30.0-0.1-0.10.2-0.5
Time to tail flick, vehicle, before self-admin1.61.72.4-1.21.4-1.41.41.31.60.5
Time to tail flick, vehicle, after self-admin0.80.91.6-1.01.3-0.90.60.61.0-1.0
Time to tail flick, test, before self-admin0.60.62.4-0.40.2-0.50.80.80.21.6
Time to tail flick, test, after self-admin0.10.10.50.0-0.00.1-0.3-0.30.1-0.7
Delta time to tail flick, vehicle, before/after SA0.70.62.00.5-0.30.7-0.9-0.8-0.5-1.4
Delta time to tail flick, test, before/after SA0.50.41.00.5-0.40.6-0.8-0.7-0.4-1.0
Tibia length5.916.622.2-4.74.5-4.34.14.14.22.1
Ambulatory time before self-admin0.50.61.40.6-0.30.7-0.7-0.8-0.6-1.2
Ambulatory time after self-admin0.10.10.30.1-0.30.3-0.2-0.2-0.60.1
Bone: tissue strength2.12.03.4-1.51.8-1.41.21.11.8-0.7
Total heroin consumption0.91.01.9-1.41.2-1.00.80.81.1-0.5
Bone: trabecular number0.71.12.01.0-1.30.9-0.5-0.4-1.41.4
Bone: trabecular spacing1.31.62.9-1.31.6-1.20.80.71.7-1.3
Bone: trabecular thickness0.40.52.5-0.2-0.0-0.30.50.6-0.11.6
Bone: trabecular tissue density0.30.40.6-0.60.5-0.80.70.80.60.6
Water consumed over 24 hours0.20.31.4-0.10.30.1-0.3-0.40.2-1.2
Number of responses in last shaping day0.70.71.20.7-0.70.8-1.1-0.9-0.5-1.0