Hub : Traits

Cd content in liver

Tags: Physiology · Liver

Project: vulpe_liver_2014

1 locus · 1 gene with independent associations · 1 total associated gene

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr10	24487967	25881097	1	1	1.42e-07	6.22e-06	1e+00	Ccng1

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
Body weight	1.52	1	0	0	0	1e+00	Ccng1
Tail length	1.97	1	0	0	0	1e+00	Ccng1
Locomotor activity	11.41	1	0	0	0	1e+00	Ccng1
Locomotor testing distance	16.98	1	1	100	0	1e+00	Ccng1
Locomotor testing rearing	15.96	1	1	100	0	1e+00	Ccng1
Light reinforcement 2	4.68	1	0	0	0	1e+00	Ccng1
Reaction time number correct	6.59	1	0	0	0	1e+00	Ccng1
Reaction time mean minus median	10.94	1	0	0	0	1e+00	Ccng1
Reaction time mean minus median AUC	11.02	1	0	0	0	1e+00	Ccng1
Reaction time trials correct on left	6.59	1	0	0	0	1e+00	Ccng1
Reaction time trials on left	6.32	1	0	0	0	1e+00	Ccng1
Reaction time mean	11.17	1	0	0	0	1e+00	Ccng1
Reaction time mean AUC	12.67	1	0	0	0	1e+00	Ccng1
Median of all reaction times	7.5	1	0	0	0	1e+00	Ccng1
Std. dev. reaction times	9.8	1	0	0	0	1e+00	Ccng1
Reaction time trials completed	6.32	1	0	0	0	1e+00	Ccng1
Reaction time trials AUC	6.64	1	0	0	0	1e+00	Ccng1
Pavlov. Cond. magazine entry latency	4.69	1	0	0	0	1e+00	Ccng1
Intermittent access total infusions	5.54	1	0	0	0	1e+00	Ccng1
Intermittent access standard deviation	7.4	1	0	0	0	1e+00	Ccng1
Cocaine induced anxiety	5.7	1	0	0	0	1e+00	Ccng1
Baseline Anxiety	8.14	1	0	0	0	1e+00	Ccng1
Lifetime Intake	4.55	1	0	0	0	1e+00	Ccng1
Incentive Sensitization - Responses	5.93	1	0	0	0	1e+00	Ccng1
Incentive Sensitization - Breakpoint	6.75	1	0	0	0	1e+00	Ccng1
Short access day 10 total infusions	4.66	1	0	0	0	1e+00	Ccng1
Bone: cortical thickness	3.77	1	0	0	0	1e+00	Ccng1
Delay disc. indifference point, 0s delay	5.73	1	0	0	0	1e+00	Ccng1
Delay disc. indifference point, 24s delay	7.1	1	0	0	0	1e+00	Ccng1
Total resting periods, locomotor time 1	5.14	1	0	0	0	1e+00	Ccng1
Distance moved, locomotor task time 1	5.62	1	0	0	0	1e+00	Ccng1
Rest time, locomotor task time 2	12.98	1	0	0	0	1e+00	Ccng1
Distance moved, locomotor task time 2	8.38	1	0	0	0	1e+00	Ccng1
Run reversals in cocaine runway, females	6.14	1	0	0	0	1e+00	Ccng1
Na content in liver	5.12	1	0	0	0	1e+00	Ccng1

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.04
Adipose	alternative TSS	0	0	1.08
Adipose	gene expression	0	0	1.12
Adipose	isoform ratio	0	0	1.1
Adipose	intron excision ratio	0	0	1.16
Adipose	mRNA stability	0	0	1.14
BLA	alternative polyA	0	0	1.04
BLA	alternative TSS	0	0	0.97
BLA	gene expression	0	0	1.11
BLA	isoform ratio	0	0	1.1
BLA	intron excision ratio	0	0	1.1
BLA	mRNA stability	0	0	1.09
Brain	alternative polyA	0	0	1.06
Brain	alternative TSS	0	0	1.08
Brain	gene expression	0	0	1.11
Brain	isoform ratio	0	0	1.11
Brain	intron excision ratio	0	0	1.14
Brain	mRNA stability	0	0	1.11
Eye	alternative polyA	0	0	0.97
Eye	alternative TSS	0	0	0.86
Eye	gene expression	0	0	1.07
Eye	isoform ratio	0	0	1.04
Eye	intron excision ratio	0	0	1.06
Eye	mRNA stability	0	0	1.23
IL	alternative polyA	0	0	1.02
IL	alternative TSS	0	0	1.02
IL	gene expression	0	0	1.13
IL	isoform ratio	0	0	1.13
IL	intron excision ratio	0	0	1.15
IL	mRNA stability	0	0	1.21
LHb	alternative polyA	0	0	1.06
LHb	alternative TSS	0	0	1.03
LHb	gene expression	0	0	1.13
LHb	isoform ratio	0	0	1.12
LHb	intron excision ratio	0	0	0.99
LHb	mRNA stability	0	0	1.18
Liver	alternative polyA	0	0	1.07
Liver	alternative TSS	0	0	1.08
Liver	gene expression	0	0	1.09
Liver	isoform ratio	0	0	1.03
Liver	intron excision ratio	0	0	1.19
Liver	mRNA stability	0	0	1.11
NAcc	alternative polyA	0	0	1.08
NAcc	alternative TSS	0	0	1.03
NAcc	gene expression	0	0	1.1
NAcc	isoform ratio	0	0	1.11
NAcc	intron excision ratio	0	0	1.08
NAcc	mRNA stability	1	0	1.12
OFC	alternative polyA	0	0	1.19
OFC	alternative TSS	0	0	1.21
OFC	gene expression	0	0	1.1
OFC	isoform ratio	0	0	1.13
OFC	intron excision ratio	0	0	1.11
OFC	mRNA stability	0	0	1.17
PL	alternative polyA	0	0	1.04
PL	alternative TSS	0	0	1.08
PL	gene expression	1	0	1.13
PL	isoform ratio	0	0	1.08
PL	intron excision ratio	0	0	1.09
PL	mRNA stability	0	0	1.12
pVTA	alternative polyA	0	0	1.04
pVTA	alternative TSS	0	0	0.99
pVTA	gene expression	0	0	1.11
pVTA	isoform ratio	0	0	1.04
pVTA	intron excision ratio	0	0	1.12
pVTA	mRNA stability	0	0	1.12
RMTg	alternative polyA	0	0	1.07
RMTg	alternative TSS	0	0	1.09
RMTg	gene expression	0	0	1.13
RMTg	isoform ratio	0	0	1.06
RMTg	intron excision ratio	0	0	1.04
RMTg	mRNA stability	0	0	1.03