Hub : Genes

Rhebl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr7_130028333_130029695 0.37 0.35 8.6e-04 0.03 0.02 0.01 0.03 1.2e-03 2.6e-03 1.3e-02 1.5e-03
2 Adipose gene expression Rhebl1 0.04 0.04 2.7e-04 0.02 0.02 0.02 0.02 1.1e-03 9.3e-04 8.7e-04 1.7e-03
3 OFC alternative polyA NM_182825.2 0.15 0.12 2.4e-03 0.07 0.09 0.04 0.07 9.4e-03 4.5e-03 4.6e-02 8.6e-03
4 BLA alternative polyA XM_039079358.1 0.15 0.12 3.8e-07 0.1 0.11 0.09 0.1 6.1e-06 2.9e-06 1.1e-05 3.7e-06
5 PL gene expression Rhebl1 0.04 0.04 3.7e-05 0.03 0.04 0.03 0.03 1.1e-04 7.6e-05 1.0e-04 1.3e-04
6 pVTA alternative polyA XM_039079358.1 0.09 0.09 3.6e-03 0.03 0.04 0.03 0.03 1.3e-02 1.0e-02 1.7e-02 1.8e-02
7 NAcc alternative polyA NM_182825.2 0.12 0.12 1.0e-11 0.09 0.1 0.09 0.1 1.5e-10 9.2e-12 3.8e-10 4.1e-11
8 PL alternative polyA NM_182825.2 0.13 0.08 0.0e+00 0.17 0.18 0.18 0.18 3.4e-18 4.3e-19 6.0e-19 2.9e-19
9 Brain alternative polyA XM_039079358.1 0.08 0.07 1.8e-07 0.08 0.07 0.08 0.08 1.1e-07 2.6e-07 1.1e-07 1.4e-07
10 PL alternative polyA XM_039079358.1 0.1 0.06 2.2e-14 0.14 0.13 0.13 0.14 5.8e-15 2.1e-14 2.1e-14 1.3e-14
11 PL isoform ratio XM_008765755.3 0.04 0.04 4.7e-04 0.03 0.03 0.03 0.03 4.1e-04 3.9e-04 2.8e-04 4.7e-04
12 BLA alternative polyA NM_182825.2 0.13 0.11 2.4e-06 0.1 0.1 0.1 0.09 7.6e-06 8.9e-06 6.9e-06 1.0e-05
13 NAcc intron excision ratio chr7_130028333_130029695 0.05 0.05 4.4e-05 0.03 0.03 0.03 0.03 2.1e-04 2.1e-04 2.3e-04 1.1e-04
14 NAcc alternative polyA XM_039079358.1 0.16 0.2 1.6e-11 0.1 0.1 0.09 0.1 1.1e-11 1.9e-11 1.3e-10 2.1e-11
15 NAcc intron excision ratio chr7_130028333_130029361 0.03 0.03 8.2e-04 0.03 0.02 0.02 0.02 6.5e-04 1.2e-03 1.2e-03 1.5e-03
16 PL intron excision ratio chr7_130028333_130029695 0.03 0.03 2.1e-03 0.02 0.02 0.02 0.02 3.3e-03 4.5e-03 4.6e-03 6.5e-03
17 Brain alternative polyA NM_182825.2 0.43 0.25 1.7e-10 0.11 0.11 0.12 0.12 1.7e-10 1.3e-10 3.6e-11 8.4e-11
18 Brain isoform ratio NM_182825.2 0.04 0.04 4.2e-04 0.03 0.03 0.04 0.03 6.2e-04 1.1e-03 2.1e-04 4.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density10.417.519.24.34.34.2-4.2-4.2-4.24.24.34.44.34.2-4.2-4.24.1-4.14.1-4.1-3.2
Area under the delay curve0.91.01.31.00.91.0-1.0-1.0-1.11.11.00.91.01.1-1.1-1.11.1-1.11.1-0.5-0.3
BMI with tail4.013.116.13.63.63.8-3.8-3.8-3.93.93.83.53.63.9-4.0-3.83.9-3.83.8-2.4-0.9
BMI without tail0.10.11.0-0.3-0.3-0.10.00.0-0.00.0-0.1-0.3-0.20.2-0.3-0.10.3-0.30.31.00.6
Body weight5.824.428.94.94.95.2-5.2-5.2-5.35.35.14.84.95.2-5.4-5.25.3-5.35.2-3.4-1.8
Weight adjusted by age2.12.43.31.41.41.5-1.6-1.6-1.61.61.51.31.51.6-1.7-1.71.8-1.71.8-0.8-1.3
Bone surface12.121.222.94.84.84.7-4.7-4.7-4.74.74.74.84.74.7-4.6-4.74.6-4.64.6-4.3-3.4
Bone volume9.215.617.34.14.14.0-4.0-4.0-4.04.04.04.24.14.0-3.9-4.03.9-3.93.9-3.9-3.2
Breakpoint value in progressive ratio session0.20.20.30.40.50.5-0.5-0.5-0.50.50.40.30.30.4-0.5-0.40.5-0.50.5-0.1-0.4
Number of licking bursts0.30.41.3-0.8-0.8-0.60.60.60.5-0.5-0.6-0.8-0.8-0.40.30.5-0.30.3-0.31.10.7
Context. condit. distance diff. score0.20.30.50.50.50.5-0.6-0.6-0.60.60.50.40.50.5-0.6-0.60.7-0.70.7-0.10.1
Locomotion velocity, session 11.11.21.6-1.1-1.1-1.11.11.11.1-1.1-1.1-1.1-1.1-1.21.21.1-1.11.1-1.10.90.9
Locomotion distance, session 12.83.54.5-1.9-1.9-1.91.91.92.0-2.0-2.0-1.8-1.8-2.12.12.0-2.02.0-2.01.40.9
Locomotion velocity, session 20.20.20.5-0.4-0.4-0.50.50.50.5-0.5-0.5-0.3-0.4-0.60.70.5-0.50.5-0.6-0.00.1
Locomotion distance, session 22.23.03.9-1.7-1.7-1.81.81.81.8-1.8-1.8-1.6-1.7-2.02.01.8-1.81.8-1.91.10.9
Locomotion velocity, session 33.64.24.7-2.1-2.1-2.22.22.22.2-2.2-2.1-2.0-2.1-2.12.22.1-2.02.0-2.11.61.5
Locomotion distance, session 34.54.96.2-2.2-2.2-2.42.42.42.4-2.4-2.3-2.0-2.2-2.42.52.3-2.42.4-2.31.30.6
Stereotopy head waving bouts, day 31.31.62.31.31.41.2-1.2-1.2-1.21.21.31.51.31.3-1.2-1.21.3-1.31.2-1.5-0.6
Stereotopy head waving duration, day 30.60.71.00.90.90.8-0.8-0.8-0.80.80.91.00.90.9-0.7-0.70.8-0.80.7-1.00.2
Locomotion velocity, session 70.10.20.3-0.4-0.4-0.50.50.50.5-0.5-0.4-0.3-0.4-0.50.40.4-0.40.4-0.30.1-0.4
Locomotion distance, session 71.41.82.2-1.4-1.4-1.51.51.51.5-1.4-1.4-1.3-1.4-1.51.41.3-1.31.3-1.30.90.3
Stereotopy head waving bouts, day 71.01.21.71.11.11.1-1.1-1.0-1.11.11.11.21.11.3-1.2-1.11.2-1.21.1-1.0-0.5
Stereotopy head waving duration, day 71.21.42.11.21.21.2-1.2-1.2-1.21.21.21.21.21.5-1.3-1.21.3-1.31.2-0.9-0.1
Locomotion velocity, session 80.00.00.2-0.0-0.00.1-0.1-0.1-0.10.10.0-0.1-0.1-0.0-0.0-0.10.1-0.10.10.30.4
Locomotion distance, session 81.11.72.1-1.3-1.3-1.31.31.31.3-1.3-1.3-1.3-1.3-1.41.41.3-1.31.3-1.31.01.2
Degree of sensitization distance0.50.50.70.70.70.7-0.7-0.7-0.80.80.70.60.70.7-0.9-0.80.8-0.80.8-0.30.0
Degree of sensitization stereotypy0.20.20.50.30.30.4-0.4-0.4-0.50.50.40.40.30.7-0.5-0.50.6-0.60.5-0.1-0.3
Conditioned locomotion0.10.10.30.20.20.2-0.2-0.2-0.20.20.20.30.30.1-0.1-0.20.1-0.10.1-0.4-0.6
Cocaine response after cond. corrected0.00.00.0-0.0-0.0-0.10.10.10.1-0.1-0.1-0.0-0.1-0.20.10.1-0.10.1-0.1-0.0-0.1
Cocaine response after cond. not corrected0.60.60.8-0.7-0.7-0.80.80.80.8-0.8-0.8-0.7-0.8-0.90.90.8-0.90.9-0.90.50.6
Cocaine response before conditioning3.54.35.1-2.0-2.0-2.12.12.12.1-2.2-2.0-2.0-2.0-2.12.12.2-2.32.2-2.31.41.7
Saline control response0.10.10.50.50.50.4-0.4-0.4-0.40.30.40.50.40.3-0.3-0.30.2-0.20.2-0.70.3
Bone: connectivity density7.511.813.03.63.63.5-3.5-3.5-3.53.53.53.63.63.5-3.4-3.53.4-3.43.4-3.4-2.5
Bone: cortical apparent density0.30.30.5-0.5-0.5-0.60.60.60.7-0.6-0.6-0.4-0.6-0.70.60.6-0.70.7-0.70.0-0.3
Bone: cortical area9.514.416.73.83.83.9-3.9-3.9-4.04.03.83.73.84.1-4.0-4.04.0-4.04.0-2.9-2.3
Bone: cortical porosity0.91.01.6-0.8-0.8-1.01.01.01.1-1.1-1.0-0.7-0.8-1.11.31.1-1.31.3-1.30.00.7
Bone: cortical porosity1.31.52.3-1.0-1.0-1.21.21.21.3-1.3-1.2-0.9-1.0-1.31.51.4-1.51.5-1.50.10.8
Bone: cortical thickness3.65.87.72.32.32.5-2.5-2.5-2.62.62.32.22.22.7-2.6-2.72.8-2.82.8-1.3-1.3
Bone: cortical thickness0.20.20.40.30.30.4-0.4-0.4-0.50.50.30.20.20.5-0.6-0.50.6-0.60.60.20.1
Bone: cortical tissue density0.40.50.7-0.6-0.6-0.70.70.80.8-0.8-0.7-0.5-0.7-0.80.70.7-0.80.8-0.80.0-0.2
Condit. Reinf. active minus inactive responses0.10.10.4-0.2-0.2-0.20.20.20.2-0.2-0.3-0.1-0.2-0.30.30.2-0.20.2-0.2-0.0-0.6
Condit. Reinf. active-inactive response ratio0.40.42.30.60.60.5-0.5-0.5-0.40.50.50.60.60.3-0.4-0.50.5-0.40.5-0.8-1.5
Condit. Reinf. active responses0.50.60.8-0.8-0.8-0.80.80.80.8-0.8-0.9-0.8-0.8-0.90.80.8-0.70.7-0.80.70.3
Condit. Reinf. inactive responses2.83.34.0-1.9-1.9-1.81.81.81.8-1.8-1.8-1.9-1.8-1.81.81.8-1.81.7-1.81.82.0
Incentive salience index mean0.10.10.70.10.10.2-0.2-0.2-0.20.20.10.20.10.1-0.2-0.30.4-0.40.30.0-0.8
Condit. Reinf. lever presses0.20.30.70.30.30.4-0.5-0.5-0.50.50.30.30.30.4-0.5-0.60.8-0.70.70.1-0.8
Condit. Reinf. active minus inactive responses0.00.10.3-0.1-0.1-0.20.20.20.2-0.2-0.0-0.0-0.1-0.10.10.2-0.30.3-0.3-0.20.6
Condit. Reinf. active-inactive response ratio0.40.40.5-0.6-0.6-0.60.60.60.6-0.6-0.6-0.7-0.6-0.60.60.6-0.60.6-0.60.70.7
Condit. Reinf. active responses0.20.30.7-0.4-0.4-0.50.50.60.6-0.6-0.4-0.3-0.4-0.50.50.6-0.70.7-0.7-0.10.8
Condit. Reinf. inactive responses0.60.70.9-0.8-0.8-0.90.90.90.9-0.9-0.8-0.7-0.8-0.80.90.9-1.01.0-1.00.30.9
Condit. Reinf. lever presses0.00.00.20.10.1-0.00.00.00.0-0.00.00.10.00.0-0.00.0-0.10.1-0.1-0.4-0.2
Condit. Reinf. lever reinforcers received0.50.71.0-0.8-0.8-0.90.90.90.9-0.9-0.8-0.7-0.8-0.80.80.9-1.01.0-1.00.30.9
Conditioned reinforcement - actives1.61.62.3-1.5-1.5-1.31.31.31.3-1.3-1.1-1.5-1.3-1.11.11.2-1.11.2-1.21.51.3
Conditioned reinforcement - inactives2.02.33.9-1.7-1.7-1.51.51.51.5-1.5-1.4-1.7-1.4-1.31.41.4-1.31.3-1.32.01.4
Conditioned locomotion0.50.62.3-0.9-0.9-0.70.70.70.7-0.7-0.5-0.9-0.6-0.60.60.6-0.60.6-0.61.11.5
Patch foraging indifference point 0 sec2.23.53.9-2.0-1.9-1.91.91.91.9-1.9-1.9-2.0-2.0-1.81.91.9-1.91.8-1.81.81.8
Patch foraging indifference point AUC0.20.20.3-0.5-0.5-0.50.50.50.5-0.5-0.4-0.5-0.5-0.30.30.5-0.50.6-0.50.40.6
Delay disc. indifference point, 0s delay1.11.21.51.11.01.2-1.2-1.1-1.21.11.21.11.21.2-1.2-1.11.1-1.01.0-0.90.5
Delay disc. indifference point, 16s delay1.01.01.50.80.81.0-1.0-1.0-1.01.01.00.81.01.1-1.1-1.11.1-1.21.2-0.3-0.7
Delay disc. indifference point, 2s delay1.31.51.91.41.31.3-1.3-1.3-1.21.21.21.41.21.2-1.2-1.21.2-1.11.1-1.3-0.7
Delay disc. indifference point, 24s delay1.31.21.61.11.11.2-1.2-1.2-1.21.21.21.01.11.2-1.2-1.11.3-1.21.2-0.6-0.0
Delay disc. indifference point, 4s delay0.30.30.40.60.50.5-0.5-0.5-0.50.50.60.60.50.5-0.6-0.50.5-0.50.5-0.6-0.3
Delay disc. indifference point, 8s delay2.52.63.31.51.51.7-1.7-1.7-1.71.71.71.51.61.8-1.7-1.71.8-1.81.8-0.9-0.6
Indifference point function ln k3.75.16.12.42.32.3-2.3-2.3-2.32.32.42.32.52.2-2.2-2.32.2-2.22.2-2.1-1.5
Indifference point function log k3.75.16.12.42.32.3-2.3-2.3-2.32.32.42.32.52.2-2.2-2.32.2-2.22.2-2.1-1.5
Patch foraging total patch changes 0 sec2.13.43.9-1.9-1.9-1.91.91.91.8-1.9-1.9-1.9-2.0-1.71.81.9-1.91.8-1.81.71.8
Patch foraging total patch changes 12 sec2.02.54.1-1.8-1.8-1.61.61.61.6-1.6-1.6-1.8-1.8-1.41.41.5-1.41.4-1.32.01.0
Patch foraging total patch changes 18 sec4.15.26.1-2.3-2.3-2.42.42.42.4-2.4-2.3-2.2-2.3-2.22.22.4-2.52.4-2.41.71.9
Patch foraging total patch changes 24 sec1.92.32.9-1.6-1.6-1.61.61.61.6-1.6-1.6-1.6-1.7-1.41.41.5-1.51.4-1.41.40.8
Patch foraging total patch changes 6 sec2.43.53.9-2.0-1.9-1.91.92.01.9-1.9-1.9-1.9-2.0-1.81.81.9-1.91.8-1.91.61.5
Patch foraging time to switch 0 sec2.13.34.3-1.8-1.8-1.91.91.91.9-1.9-1.9-1.8-1.9-2.11.91.8-1.91.8-1.81.50.5
Patch foraging water rate 0 sec2.84.55.72.12.12.2-2.2-2.2-2.22.22.22.12.12.4-2.3-2.22.2-2.32.2-1.7-0.5
Patch foraging water rate 12 sec3.65.56.52.52.52.4-2.4-2.4-2.42.42.52.52.62.4-2.3-2.32.3-2.32.2-2.3-1.0
Patch foraging water rate 18 sec0.30.40.70.50.50.6-0.6-0.6-0.60.60.50.50.50.7-0.6-0.60.8-0.80.7-0.2-0.4
Patch foraging water rate 24 sec3.14.34.82.22.12.1-2.1-2.1-2.12.12.12.12.12.1-2.1-2.12.1-2.22.1-1.9-0.8
Patch foraging water rate 6 sec3.65.36.02.42.42.3-2.4-2.4-2.42.42.42.42.52.4-2.3-2.32.4-2.32.3-2.2-1.2
Seeking ratio, delayed vs. immediate footshock0.30.40.60.50.60.6-0.6-0.6-0.60.60.60.60.60.7-0.6-0.70.6-0.80.7-0.3-0.4
Distance traveled before self-admin1.01.11.3-1.1-1.0-1.11.11.11.1-1.1-1.1-1.1-1.1-1.11.11.1-1.01.0-1.10.90.5
Distance traveled after self-admin0.10.20.3-0.4-0.4-0.40.40.40.4-0.4-0.4-0.4-0.3-0.50.40.4-0.60.3-0.40.30.4
Extensor digitorum longus weight3.815.120.13.63.64.0-4.1-4.1-4.24.23.83.43.54.1-4.3-4.34.5-4.54.5-1.8-2.3
Bone: elastic displacement4.34.96.0-2.2-2.2-2.32.32.32.3-2.3-2.3-2.2-2.2-2.42.42.3-2.42.4-2.41.61.0
Bone: elastic work0.10.10.50.20.20.00.00.00.1-0.1-0.00.20.1-0.30.20.1-0.20.2-0.2-0.6-0.7
Bone: endosteal estimation7.516.318.74.24.24.1-4.1-4.1-4.14.14.24.24.34.0-4.0-4.03.9-3.93.9-4.0-2.9
Bone: endosteal perimeter6.613.615.33.73.73.8-3.8-3.8-3.83.83.83.73.83.9-3.8-3.83.8-3.83.8-3.0-2.4
Epididymis fat weight0.10.30.70.70.60.6-0.6-0.6-0.60.60.60.70.70.4-0.5-0.50.4-0.40.4-0.90.6
Delta time in closed arm before/after self-admin0.20.20.50.50.60.5-0.5-0.5-0.50.50.40.60.40.5-0.4-0.30.5-0.40.2-0.7-0.3
Delta time in open arm before/after self-admin4.14.04.6-2.1-2.1-2.12.12.02.0-2.0-2.0-2.1-2.0-2.12.01.9-2.01.9-1.92.01.3
Diff in mean of infusions in LGA sessions1.51.61.91.31.41.3-1.3-1.3-1.31.31.31.31.31.3-1.3-1.31.3-1.21.2-1.2-0.9
Delay discount exponential model param0.80.91.1-0.9-0.8-1.01.01.01.0-1.0-1.0-0.9-0.9-1.01.11.0-1.11.0-1.00.50.4
Extinction: sum of active levers before priming0.40.40.50.70.70.7-0.7-0.7-0.60.70.60.60.60.6-0.6-0.60.5-0.60.6-0.5-0.4
Active lever presses in extinction session 60.50.40.60.60.70.7-0.7-0.7-0.70.70.60.60.60.6-0.7-0.70.7-0.80.7-0.4-0.7
Bone: final force9.916.017.24.14.14.1-4.1-4.1-4.14.14.14.04.14.1-4.0-4.14.1-4.14.1-3.4-2.7
Bone: final moment10.316.818.14.34.34.3-4.2-4.2-4.24.24.24.24.24.1-4.1-4.24.1-4.14.1-3.7-2.7
Food consumed during 24 hour testing period1.82.22.61.51.51.5-1.5-1.5-1.51.51.51.51.51.6-1.5-1.51.5-1.51.5-1.5-0.9
Glucose0.10.10.20.10.20.3-0.3-0.3-0.30.30.20.10.10.4-0.4-0.40.5-0.50.50.3-0.3
Heart weight0.00.00.10.20.20.3-0.3-0.3-0.20.30.20.10.30.2-0.1-0.20.1-0.20.2-0.00.0
Delay discount hyperbolic model param0.80.91.1-0.9-0.8-0.91.01.01.0-1.0-1.0-0.9-0.9-1.01.01.0-1.01.0-1.00.60.4
Intermittent access intake day 1-15 change1.31.31.6-1.3-1.3-1.21.21.21.2-1.2-1.1-1.2-1.2-1.21.11.1-0.91.0-1.01.20.4
Intermittent access intake escalation0.90.91.1-1.1-1.1-1.01.01.01.0-1.0-0.9-1.0-1.0-1.00.90.9-0.70.9-0.91.00.2
Intermittent access intake escalation 21.41.41.8-1.4-1.4-1.31.31.31.2-1.2-1.2-1.3-1.2-1.21.11.1-1.01.1-1.11.30.3
Intermitt. access day 1 inactive lever presses3.13.34.0-1.6-1.6-1.81.81.81.8-1.8-1.9-1.7-1.9-1.92.02.0-2.02.0-2.01.11.6
Intermitt. access day 15 inactive lever presses1.21.41.7-1.2-1.2-1.21.21.21.2-1.2-1.1-1.1-1.1-1.31.21.2-1.21.2-1.20.90.8
Intermitt. access escalation Index0.20.20.5-0.3-0.3-0.50.40.40.5-0.4-0.7-0.3-0.5-0.60.50.4-0.30.4-0.40.1-0.4
Intermittent access day 1 total infusions1.21.41.8-1.3-1.3-1.21.21.21.2-1.2-1.2-1.3-1.1-1.11.21.1-1.11.1-1.11.31.3
Intermittent access day 15 total infusions2.52.83.6-1.9-1.9-1.81.81.71.7-1.7-1.7-1.8-1.7-1.71.71.6-1.41.5-1.51.81.1
Intermittent access terminal intake (last 3 days)2.73.03.7-1.9-1.9-1.81.81.81.8-1.8-1.7-1.8-1.6-1.71.81.7-1.61.7-1.71.61.0
Intermittent access total infusions2.52.83.5-1.9-1.9-1.81.71.71.7-1.7-1.7-1.8-1.6-1.61.71.6-1.51.5-1.51.81.0
Intermittent access day 1 locomotion1.01.01.2-1.0-1.0-1.01.01.01.0-1.0-1.1-1.1-1.0-1.01.11.0-1.01.0-1.00.91.1
Intermittent access day 15 total locomotion1.71.82.8-1.6-1.6-1.31.31.31.3-1.3-1.2-1.6-1.2-1.21.21.2-1.21.2-1.21.71.6
Intermittent access total locomotion3.43.94.7-2.2-2.2-2.02.02.02.0-2.0-2.0-2.2-1.9-1.91.91.9-1.81.9-1.92.01.9
Intermittent access standard deviation0.50.50.9-0.8-0.8-0.80.70.70.7-0.7-0.7-0.8-0.8-0.70.70.7-0.50.6-0.61.00.6
Left kidney weight0.31.01.31.01.01.0-1.0-1.0-1.11.01.00.91.21.1-1.0-1.01.0-1.01.0-0.7-0.5
Right kidney weight2.67.49.02.62.62.8-2.8-2.8-2.82.83.02.63.02.9-3.0-2.92.8-2.82.8-2.0-1.5
Cocaine induced anxiety1.11.21.51.11.11.1-1.1-1.1-1.11.21.11.01.11.1-1.1-1.21.2-1.21.2-0.8-1.1
Post-drug Anxiety4.95.45.92.42.42.4-2.4-2.4-2.42.42.42.32.42.3-2.3-2.42.3-2.42.4-2.0-1.6
Baseline Anxiety0.91.01.21.01.01.0-1.1-1.1-1.11.11.01.01.01.0-1.0-1.11.1-1.11.1-0.6-0.6
Tail length0.10.20.4-0.6-0.6-0.50.50.50.5-0.5-0.4-0.5-0.4-0.40.30.4-0.40.3-0.40.60.4
Length with tail1.86.77.52.72.72.7-2.7-2.7-2.72.72.72.62.72.6-2.7-2.72.6-2.72.6-2.1-1.0
Length without tail7.115.517.64.14.14.2-4.2-4.2-4.24.24.13.94.04.0-4.0-4.04.1-4.14.0-3.1-1.6
Times rat made contact with spout0.10.10.6-0.4-0.4-0.30.20.20.2-0.2-0.4-0.5-0.4-0.10.20.2-0.00.0-0.00.80.2
Lifetime Intake2.32.64.0-1.9-1.9-1.71.71.71.6-1.6-1.7-1.9-1.6-1.51.61.4-1.31.4-1.42.00.9
Liver weight, left1.82.93.61.61.71.8-1.8-1.8-1.81.81.71.61.61.8-1.9-1.81.9-1.91.9-1.1-1.2
Liver weight, right1.42.42.71.61.61.6-1.6-1.6-1.61.61.51.51.61.6-1.6-1.61.7-1.61.6-1.2-0.9
Locomotor activity1.01.52.1-1.4-1.5-1.41.31.31.3-1.3-1.3-1.4-1.3-1.21.21.1-1.01.0-1.01.40.3
Locomotor testing distance2.74.55.2-2.2-2.3-2.32.32.22.2-2.2-2.2-2.1-2.2-2.12.12.1-2.12.0-2.01.81.2
Locomotor testing rearing2.23.43.8-1.9-1.9-1.91.91.91.9-1.9-1.9-1.9-1.9-1.91.81.8-1.91.8-1.81.61.4
Locomotion in novel chamber0.50.70.80.80.80.8-0.8-0.8-0.80.80.80.90.80.9-0.9-0.70.8-0.80.7-0.8-0.5
Locomotion in novel chamber post-restriction0.00.00.10.20.10.1-0.1-0.1-0.10.10.20.30.20.2-0.2-0.20.2-0.10.1-0.4-0.2
Fecal boli incidents, locomotor time 11.82.02.8-1.6-1.6-1.51.51.51.4-1.4-1.6-1.6-1.5-1.41.41.3-1.31.1-1.11.7-0.1
Change in fecal boli incidents, locomotor task1.51.42.01.21.21.2-1.2-1.2-1.11.11.31.31.31.1-1.1-1.21.2-1.01.1-1.3-1.4
Time >=10cm from walls, locomotor time 10.20.21.00.40.40.4-0.4-0.4-0.40.40.40.40.40.4-0.3-0.50.5-0.40.5-0.4-1.0
Bouts of movement, locomotor time 10.00.10.6-0.10.00.1-0.1-0.1-0.10.10.1-0.10.2-0.00.0-0.20.1-0.30.20.3-0.8
Total resting periods, locomotor time 10.20.20.6-0.6-0.5-0.40.40.40.4-0.4-0.5-0.6-0.3-0.50.50.4-0.50.3-0.40.8-0.1
Rest time, locomotor task time 10.30.31.0-0.7-0.6-0.60.60.60.5-0.5-0.6-0.8-0.6-0.60.60.5-0.50.3-0.41.0-0.0
Distance moved, locomotor task time 10.10.10.60.30.30.1-0.1-0.1-0.10.00.10.40.20.1-0.10.0-0.00.2-0.1-0.70.3
Vertical activity count, locomotor time 11.21.31.61.21.11.2-1.2-1.2-1.21.21.21.21.21.2-1.2-1.11.2-1.01.1-1.10.0
Time >=10cm from walls, locomotor time 20.50.60.9-0.8-0.9-0.80.80.80.8-0.8-0.7-0.8-0.7-0.70.80.6-0.60.6-0.60.80.5
Bouts of movement, locomotor time 22.22.43.21.61.61.7-1.7-1.7-1.71.71.71.61.81.6-1.7-1.51.5-1.51.4-1.10.5
Total resting periods, locomotor time 22.62.83.61.71.71.8-1.8-1.8-1.81.81.91.71.91.7-1.8-1.71.6-1.71.6-1.3-0.1
Rest time, locomotor task time 20.10.10.60.10.20.2-0.2-0.2-0.20.20.10.10.10.1-0.2-0.20.1-0.40.30.1-0.8
Distance moved, locomotor task time 20.10.20.7-0.2-0.2-0.30.30.30.4-0.4-0.3-0.2-0.2-0.40.50.4-0.30.6-0.5-0.10.8
Vertical activity count, locomotor time 20.10.11.00.1-0.00.1-0.1-0.1-0.10.10.20.10.20.3-0.2-0.10.3-0.00.10.01.0
Light reinforcement 12.54.65.5-2.3-2.3-2.32.32.32.3-2.3-2.3-2.2-2.3-2.22.22.1-2.02.1-2.11.70.2
Light reinforcement 20.81.11.5-1.2-1.2-1.11.11.11.1-1.1-1.0-1.2-1.1-1.00.90.8-0.60.8-0.71.1-1.2
Bone: marrow area7.315.918.24.24.24.1-4.1-4.1-4.04.04.24.24.33.9-3.9-4.03.9-3.93.9-4.0-2.9
Bone: maximum diameter3.76.98.82.52.52.7-2.7-2.7-2.72.72.72.52.63.0-2.9-2.82.9-2.92.9-1.7-1.4
Bone: maximum force13.924.026.45.15.15.1-5.1-5.1-5.05.05.05.15.14.8-4.8-5.04.8-4.84.8-4.7-3.4
Bone: maximum moment14.424.827.95.35.35.2-5.1-5.1-5.15.15.15.35.24.8-4.8-5.04.8-4.84.8-5.0-3.5
Mean time between licks in bursts0.10.20.4-0.1-0.1-0.30.30.30.4-0.4-0.3-0.0-0.2-0.60.60.4-0.50.5-0.5-0.50.5
Mean num. licks in bursts0.00.00.20.10.10.1-0.1-0.1-0.00.0-0.00.10.1-0.10.20.0-0.10.1-0.1-0.4-0.4
Cd content in liver0.50.61.0-0.9-0.9-0.90.80.80.8-0.8-0.9-0.9-0.9-0.90.80.6-0.50.5-0.51.0-0.4
Co content in liver0.70.85.3-1.1-1.1-0.70.70.70.6-0.5-0.9-1.3-1.0-0.50.40.4-0.10.1-0.12.30.5
Cu content in liver0.81.02.30.70.70.9-1.0-1.0-1.01.10.70.50.70.8-0.8-1.11.3-1.31.30.2-1.5
Fe content in liver0.30.41.7-0.8-0.8-0.60.60.50.5-0.5-0.7-0.9-0.8-0.40.30.4-0.20.2-0.21.30.4
K content in liver0.30.30.50.30.30.5-0.5-0.5-0.60.60.40.30.40.5-0.7-0.60.7-0.70.70.4-0.4
Mg content in liver0.00.00.1-0.1-0.1-0.10.10.10.0-0.00.0-0.1-0.10.1-0.2-0.00.1-0.10.10.2-0.1
Mn content in liver0.10.10.90.40.40.2-0.2-0.2-0.20.10.40.50.40.2-0.2-0.10.0-0.00.0-1.0-0.2
Na content in liver0.10.10.4-0.3-0.3-0.20.20.20.2-0.1-0.2-0.4-0.3-0.30.10.1-0.00.0-0.00.7-0.3
Rb content in liver0.40.51.6-0.8-0.8-0.70.60.60.6-0.6-0.7-0.8-0.8-0.50.40.5-0.40.4-0.41.30.9
Se content in liver0.50.60.8-0.9-0.9-0.90.80.80.8-0.8-0.8-0.8-0.8-0.70.80.7-0.70.7-0.70.80.8
Sr content in liver0.50.40.90.50.50.6-0.6-0.6-0.60.70.50.50.50.8-0.6-0.80.9-0.90.9-0.3-0.9
Zn content in liver1.71.93.6-1.6-1.6-1.41.41.41.3-1.3-1.5-1.6-1.6-1.21.31.2-1.11.1-1.11.90.9
Bone: minimum diameter8.816.417.94.14.14.2-4.2-4.2-4.24.24.24.14.24.2-4.1-4.24.1-4.14.1-3.5-2.5
Time in familiar zone, hab. session 10.30.30.5-0.5-0.5-0.50.50.50.5-0.5-0.7-0.6-0.6-0.60.70.6-0.60.6-0.60.50.4
Time in novel zone, hab. session 10.30.30.40.50.50.5-0.5-0.5-0.50.50.60.50.50.6-0.7-0.50.5-0.50.5-0.4-0.3
Total zone transitions, hab. session 10.40.51.1-0.7-0.7-0.70.70.70.7-0.7-0.7-0.8-0.7-0.80.70.7-0.60.6-0.60.81.1
Total locomotion distance, hab. session 10.00.00.40.20.20.1-0.1-0.1-0.00.00.10.30.3-0.10.1-0.0-0.10.1-0.1-0.7-0.0
Locomotion velocity, hab. session 10.00.10.50.30.30.2-0.2-0.2-0.10.10.20.40.4-0.0-0.1-0.10.0-0.00.0-0.7-0.0
Time in familiar zone, hab. session 20.20.20.30.60.60.6-0.6-0.5-0.50.50.50.50.50.5-0.5-0.50.4-0.40.4-0.50.1
Time in novel zone, hab. session 20.20.20.3-0.5-0.5-0.50.50.50.5-0.5-0.5-0.5-0.5-0.50.50.5-0.40.4-0.40.4-0.3
Total zone transitions, hab. session 20.30.40.6-0.6-0.6-0.60.60.60.6-0.6-0.7-0.6-0.6-0.70.70.6-0.50.5-0.50.70.8
Total locomotion distance, hab. session 20.10.10.3-0.1-0.1-0.30.30.30.3-0.3-0.20.1-0.1-0.50.50.3-0.40.3-0.4-0.5-0.3
Locomotion velocity, hab. session 20.00.00.20.10.1-0.20.20.20.2-0.2-0.10.20.1-0.30.30.1-0.20.1-0.2-0.5-0.3
Novel to familiar place preference ratio1.71.82.11.31.31.4-1.4-1.4-1.41.41.31.21.31.4-1.4-1.41.4-1.41.4-1.0-1.4
Novelty place preference1.21.21.51.11.11.1-1.1-1.1-1.11.11.11.01.11.2-1.2-1.11.1-1.11.1-0.8-1.1
Time in novel zone, NPP test1.01.01.21.01.01.0-1.0-1.0-1.01.01.00.91.01.0-1.1-1.01.0-1.01.0-0.8-1.0
Total zone transitions, NPP test1.21.82.4-1.4-1.4-1.31.31.31.3-1.3-1.4-1.4-1.4-1.41.41.2-1.21.1-1.21.51.1
Total locomotion distance, NPP test1.52.02.9-1.3-1.3-1.51.51.51.6-1.5-1.5-1.2-1.3-1.71.71.5-1.51.5-1.50.70.4
Locomotion velocity, NPP test0.71.01.6-1.0-1.0-1.11.11.11.1-1.1-1.1-0.9-0.9-1.31.21.1-1.11.1-1.10.50.1
Intraocular pressure7.310.111.0-3.3-3.2-3.33.33.33.3-3.3-3.2-3.2-3.2-3.33.23.3-3.23.3-3.22.62.2
Delta distance traveled before/after self-admin0.10.10.20.30.30.3-0.3-0.3-0.30.30.30.30.40.2-0.2-0.30.1-0.20.3-0.20.3
Delta ambulatory time before/after self-admin0.00.00.10.00.00.1-0.1-0.1-0.10.10.20.10.20.1-0.1-0.10.0-0.10.10.00.3
Parametrial fat weight2.04.04.5-2.1-2.1-2.02.02.02.0-2.0-2.1-2.1-2.1-2.01.91.9-2.02.0-1.92.11.1
Pavlov. Cond. lever latency0.10.10.60.40.40.3-0.2-0.2-0.10.10.30.40.40.0-0.10.0-0.20.2-0.2-0.8-0.0
Pavlov. Cond. magazine entry latency0.00.00.10.00.00.0-0.0-0.0-0.00.00.00.10.10.00.0-0.00.1-0.00.0-0.2-0.2
Pavlov. Cond. change in total contacts0.10.10.20.00.00.1-0.2-0.2-0.20.20.10.00.00.3-0.2-0.30.4-0.40.40.30.2
Pavlov. Cond. index score0.10.10.40.00.00.1-0.2-0.2-0.20.30.10.00.00.3-0.3-0.40.6-0.50.60.4-0.5
Pavlov. Cond. latency score0.10.10.3-0.0-0.10.1-0.1-0.1-0.20.20.0-0.0-0.00.3-0.2-0.40.6-0.50.50.4-0.3
Pavlov. Cond. lever contacts0.50.51.9-0.9-0.9-0.70.70.70.6-0.6-0.8-0.9-0.9-0.50.60.5-0.30.3-0.31.40.8
Pavlov. Cond. magazine entry number0.00.00.20.20.20.1-0.1-0.1-0.10.10.20.20.20.1-0.1-0.0-0.10.0-0.1-0.30.4
Pavlov. Cond. intertrial magazine entries0.40.50.8-0.6-0.6-0.60.60.60.6-0.6-0.7-0.6-0.6-0.70.80.7-0.80.7-0.70.60.9
Pavlov. Cond. lever-magazine prob. diff.0.30.30.80.30.30.5-0.5-0.5-0.60.60.40.30.30.6-0.6-0.70.9-0.80.90.2-0.7
Pavlov. Cond. response bias0.10.10.3-0.3-0.3-0.30.30.20.2-0.2-0.3-0.3-0.3-0.20.20.1-0.00.1-0.10.5-0.1
Pavlov. Cond. lever latency0.00.00.10.10.10.1-0.1-0.1-0.10.10.10.10.20.00.1-0.0-0.00.0-0.0-0.30.1
Pavlov. Cond. magazine entry latency1.01.11.31.11.11.1-1.1-1.1-1.11.11.11.11.11.2-1.0-1.01.0-1.01.0-1.0-0.1
Pavlov. Cond. change in total contacts1.41.92.71.31.31.4-1.4-1.5-1.51.51.31.21.21.6-1.6-1.51.6-1.61.6-0.6-0.6
Pavlov. Cond. index score0.50.60.80.80.80.8-0.8-0.8-0.80.80.70.70.70.9-0.9-0.80.8-0.80.8-0.5-0.3
Pavlov. Cond. latency score0.50.60.90.80.80.8-0.9-0.9-0.90.90.80.80.70.9-0.9-0.80.9-0.90.9-0.5-0.2
Pavlov. Cond. lever contacts0.10.10.2-0.4-0.4-0.40.40.40.4-0.4-0.4-0.4-0.5-0.30.20.3-0.30.3-0.30.5-0.0
Pavlov. Cond. magazine entry number2.02.52.9-1.6-1.6-1.71.71.71.7-1.7-1.6-1.6-1.6-1.71.71.6-1.61.6-1.61.20.6
Pavlov. Cond. intertrial magazine entries4.76.26.9-2.6-2.6-2.62.62.62.6-2.6-2.6-2.6-2.6-2.42.62.5-2.42.4-2.42.21.3
Pavlov. Cond. lever-magazine prob. diff.0.81.11.31.01.01.1-1.1-1.1-1.11.11.01.00.91.2-1.1-1.11.1-1.11.1-0.7-0.4
Pavlov. Cond. response bias0.00.00.0-0.1-0.1-0.10.00.00.0-0.0-0.1-0.1-0.1-0.0-0.00.00.0-0.00.00.20.0
Time in closed arm before self-admin1.41.61.91.21.21.3-1.3-1.3-1.31.31.41.21.31.2-1.4-1.41.2-1.41.4-0.8-0.8
Time in closed arm after self-admin0.70.70.90.90.90.9-0.9-0.8-0.80.80.90.90.90.8-0.8-0.80.7-0.80.7-0.9-0.9
Time in open arm before self-admin0.60.71.30.91.00.9-0.8-0.8-0.80.80.81.00.80.8-0.8-0.70.9-0.70.6-1.1-0.6
Time in open arm after self-admin0.30.30.4-0.6-0.6-0.50.50.50.5-0.5-0.6-0.6-0.6-0.50.60.5-0.60.5-0.50.60.5
Bone: periosteal estimation11.724.126.05.05.05.0-5.0-5.0-5.15.05.15.05.15.1-5.0-5.15.0-5.05.0-4.3-3.3
Bone: periosteal perimeter10.016.618.74.14.14.2-4.2-4.2-4.24.24.14.14.14.3-4.2-4.24.2-4.24.2-3.3-2.4
Bone: post-yield work7.910.712.33.53.53.4-3.4-3.4-3.43.33.53.53.53.3-3.3-3.23.1-3.13.1-3.4-1.6
Progressive ratio test 1 active lever presses4.24.45.6-2.4-2.4-2.22.22.22.2-2.1-2.2-2.3-2.1-2.12.12.0-1.81.9-1.92.21.0
Progressive ratio test 1 breakpoint3.94.05.3-2.3-2.3-2.12.12.12.1-2.0-2.1-2.2-2.0-2.02.01.9-1.71.8-1.82.21.0
Progressive ratio test 1 inactive lever presses3.84.14.9-2.2-2.2-2.02.02.02.0-2.0-2.0-2.2-2.1-2.02.02.0-1.91.9-1.92.21.9
Progressive ratio test 2 active lever presses2.22.33.2-1.8-1.8-1.71.61.61.6-1.6-1.5-1.7-1.4-1.61.41.4-1.41.4-1.41.60.6
Progressive ratio test 2 breakpoint2.83.14.1-2.0-2.0-1.91.91.91.9-1.8-1.7-1.9-1.7-1.81.71.7-1.71.6-1.61.80.8
Progressive ratio test 2 inactive lever presses2.63.03.6-1.9-1.9-1.81.81.81.8-1.8-1.5-1.8-1.5-1.81.71.7-1.71.7-1.71.71.5
Incentive Sensitization - Responses0.10.10.2-0.1-0.10.1-0.1-0.1-0.10.10.50.00.30.2-0.3-0.30.1-0.30.30.2-0.5
Incentive Sensitization - Breakpoint0.00.00.2-0.2-0.2-0.10.00.00.0-0.00.3-0.10.20.0-0.2-0.10.0-0.10.10.2-0.5
Sum of active levers in priming session hrs 5-60.10.10.2-0.2-0.1-0.20.20.20.2-0.2-0.2-0.2-0.2-0.30.30.3-0.40.2-0.30.10.1
Progressive ratio0.00.00.1-0.2-0.2-0.20.20.20.2-0.2-0.1-0.1-0.1-0.10.20.2-0.20.2-0.20.10.2
Food seeking constrained by brief footshock0.30.41.2-0.8-0.7-0.60.60.60.6-0.6-0.7-0.8-0.7-0.60.70.4-0.40.4-0.31.1-0.3
Seeking ratio, punishment vs. effort0.00.00.2-0.1-0.1-0.10.00.00.0-0.0-0.2-0.2-0.2-0.10.1-0.00.1-0.00.10.4-0.4
Retroperitoneal fat weight0.41.43.0-1.3-1.3-1.21.21.21.1-1.1-1.4-1.4-1.4-1.11.21.0-0.80.9-0.81.70.6
Reaction time number correct1.62.24.91.71.61.5-1.4-1.4-1.41.41.51.81.71.4-1.2-1.31.3-1.21.2-2.2-1.4
Reaction time mean minus median8.110.711.6-3.4-3.3-3.33.33.33.3-3.3-3.2-3.3-3.2-3.33.23.4-3.43.3-3.43.02.5
Reaction time mean minus median AUC5.97.68.9-2.8-2.7-2.82.82.82.8-2.8-2.7-2.7-2.7-2.92.82.9-2.92.9-3.02.32.1
Reaction time num false alarms1.62.12.9-1.4-1.4-1.51.51.51.5-1.6-1.5-1.3-1.5-1.51.61.6-1.71.6-1.60.80.8
Reaction time num false alarms AUC2.23.14.1-1.7-1.7-1.81.81.91.9-1.9-1.8-1.6-1.8-1.91.91.9-2.01.9-1.91.00.8
Reaction time trials correct on left1.62.24.91.71.61.5-1.4-1.4-1.41.41.51.81.71.4-1.2-1.31.3-1.21.2-2.2-1.4
Reaction time trials on left1.21.84.31.51.51.3-1.3-1.2-1.21.21.41.61.51.2-1.0-1.11.1-1.01.0-2.1-1.3
Reaction time mean0.70.91.8-1.0-1.0-0.90.90.90.9-0.9-0.9-1.0-0.9-0.90.80.9-0.90.8-0.91.21.3
Reaction time mean AUC0.40.51.6-0.7-0.7-0.70.70.70.6-0.6-0.6-0.8-0.6-0.60.50.7-0.60.6-0.71.01.3
Median of all reaction times0.00.00.30.10.00.1-0.1-0.1-0.20.20.20.00.20.1-0.3-0.10.2-0.20.20.20.6
Reaction time omissions9.513.014.3-3.7-3.7-3.83.83.83.8-3.8-3.7-3.6-3.5-3.73.83.7-3.73.7-3.72.92.1
Reaction time false alarm rate2.63.74.3-2.0-1.9-2.02.02.01.9-2.0-2.0-1.9-2.0-1.91.92.0-2.11.9-1.91.71.3
Reaction time premature initiation rate6.28.311.7-3.2-3.2-3.03.02.92.9-2.9-2.9-3.2-3.1-2.82.62.7-2.62.5-2.53.42.0
Reaction time premature initiations2.73.84.8-2.1-2.2-2.12.12.12.0-2.0-2.0-2.1-2.1-1.91.91.9-1.81.8-1.82.01.1
Std. dev. reaction times6.08.49.1-3.0-3.0-3.03.03.02.9-2.9-2.8-2.9-2.8-2.92.83.0-3.02.9-3.02.62.4
Reaction time trials completed1.21.84.31.51.51.3-1.3-1.2-1.21.21.41.61.51.2-1.0-1.11.1-1.01.0-2.1-1.3
Reaction time trials AUC1.92.85.91.91.81.6-1.6-1.6-1.51.51.72.01.91.6-1.4-1.51.4-1.31.3-2.4-1.5
Run reversals in cocaine runway, females0.10.11.6-0.1-0.1-0.00.00.10.1-0.1-0.0-0.2-0.1-0.00.00.2-0.20.3-0.20.11.3
Run reversals in cocaine runway, males1.41.41.6-1.2-1.2-1.21.21.21.2-1.2-1.2-1.2-1.2-1.21.21.2-1.11.2-1.11.10.7
Latency to leave start box in cocaine runway0.00.00.2-0.1-0.1-0.10.10.10.1-0.1-0.0-0.0-0.1-0.00.00.2-0.30.1-0.3-0.00.4
Latency to leave start box in cocaine runway, F1.81.92.8-1.3-1.4-1.41.41.41.4-1.4-1.4-1.3-1.3-1.41.41.5-1.71.4-1.60.90.9
Latency to leave start box in cocaine runway, M1.91.92.31.41.41.4-1.4-1.4-1.41.41.51.41.41.5-1.5-1.41.3-1.51.3-1.0-0.5
Std. dev. time between licks in bursts0.91.11.3-1.1-1.1-1.11.11.11.1-1.1-1.1-1.0-1.1-1.11.01.0-1.01.0-1.00.80.7
Total sessions with >9 infusions0.80.82.4-1.3-1.3-1.01.01.00.9-0.9-0.8-1.2-0.8-0.70.70.6-0.50.5-0.51.60.2
Short access day 1 total inactive lever presses1.41.52.5-1.4-1.4-1.31.31.31.2-1.2-1.3-1.4-1.3-1.21.11.1-1.11.0-1.01.60.9
Short access day 10 total inactive lever presses0.30.30.6-0.4-0.4-0.50.50.50.6-0.6-0.6-0.5-0.7-0.70.60.7-0.70.7-0.70.20.6
Short access day 1 total infusions0.10.10.5-0.4-0.4-0.20.20.20.1-0.1-0.2-0.4-0.1-0.10.0-0.10.1-0.10.10.7-0.3
Short access day 10 total infusions0.91.02.8-1.3-1.3-1.01.01.00.9-0.9-1.0-1.3-1.0-0.80.90.8-0.70.7-0.71.70.8
Short access total infusions0.50.52.1-1.0-1.0-0.80.70.70.6-0.6-0.7-1.0-0.7-0.50.50.4-0.30.3-0.31.40.4
Short access day 1 locomotion0.10.10.6-0.5-0.5-0.30.30.30.3-0.3-0.4-0.5-0.3-0.20.20.2-0.00.1-0.10.80.3
Short access day 10 total locomotion0.20.20.8-0.4-0.4-0.40.40.40.4-0.4-0.5-0.5-0.4-0.40.40.5-0.40.5-0.50.50.9
Short access total locomotion0.50.51.3-0.9-0.9-0.70.70.70.7-0.6-0.7-0.9-0.7-0.60.50.6-0.40.5-0.51.10.8
One hour access (0.3 mA shock)0.30.31.0-0.8-0.8-0.60.60.50.5-0.5-0.5-0.7-0.5-0.40.40.3-0.20.3-0.31.00.3
Compulsive drug intake1.01.01.31.21.21.0-1.0-1.0-1.01.00.91.10.91.0-1.0-0.90.9-0.90.9-1.1-0.7
One hour access (shock baseline)0.20.21.2-0.7-0.7-0.50.40.40.4-0.4-0.3-0.7-0.3-0.30.30.2-0.10.1-0.11.10.3
Social response proportion0.10.10.5-0.5-0.5-0.30.30.30.3-0.3-0.3-0.5-0.3-0.30.20.2-0.10.2-0.10.70.2
Social responses7.69.710.9-3.3-3.3-3.23.23.23.2-3.1-3.2-3.3-3.3-3.13.03.1-3.03.0-3.03.12.7
Social time0.00.00.3-0.2-0.2-0.00.00.00.0-0.0-0.1-0.3-0.1-0.10.10.00.00.0-0.00.60.0
Soleus weight0.51.51.81.31.31.3-1.3-1.3-1.31.31.31.21.31.3-1.3-1.31.3-1.31.3-1.0-0.4
Bone: stiffness16.626.228.75.35.35.3-5.3-5.2-5.25.25.35.45.45.1-5.2-5.25.0-5.15.0-4.9-3.4
Tibialis anterior weight0.93.15.41.41.41.8-1.8-1.8-1.92.01.61.21.32.0-2.1-2.12.3-2.32.30.1-0.8
Time to tail flick, vehicle, before self-admin0.90.91.2-0.9-0.9-1.01.01.01.0-1.1-1.0-0.9-1.0-1.01.00.9-1.11.1-0.80.5-1.1
Time to tail flick, vehicle, after self-admin0.20.20.30.50.50.5-0.5-0.5-0.50.50.50.50.50.3-0.4-0.40.5-0.50.3-0.40.1
Time to tail flick, test, before self-admin0.50.52.1-0.6-0.6-0.60.60.60.6-0.6-0.6-0.7-0.5-0.70.70.8-0.70.8-0.90.51.5
Time to tail flick, test, after self-admin0.20.20.30.40.50.4-0.4-0.4-0.40.40.50.40.50.3-0.4-0.30.3-0.30.2-0.40.4
Delta time to tail flick, vehicle, before/after SA0.40.40.60.60.60.6-0.7-0.7-0.70.70.70.60.70.6-0.7-0.60.8-0.80.6-0.30.5
Delta time to tail flick, test, before/after SA0.20.20.30.40.40.4-0.4-0.4-0.40.40.40.50.40.5-0.5-0.50.5-0.50.5-0.4-0.5
Tibia length7.220.423.54.54.54.6-4.7-4.7-4.74.74.74.54.64.7-4.8-4.74.7-4.84.7-3.5-2.4
Ambulatory time before self-admin3.94.04.4-2.0-2.0-2.12.12.02.1-2.0-2.1-2.1-2.1-2.12.02.1-2.02.0-2.01.81.5
Ambulatory time after self-admin1.71.82.1-1.4-1.4-1.41.41.41.4-1.4-1.3-1.4-1.4-1.41.31.3-1.41.2-1.31.41.0
Bone: tissue strength1.01.02.01.21.21.0-1.0-1.0-1.01.01.01.21.20.8-0.8-0.90.8-0.80.8-1.4-0.6
Total heroin consumption1.61.92.31.41.51.5-1.5-1.5-1.51.51.41.31.41.4-1.5-1.41.5-1.41.4-1.0-0.2
Bone: trabecular number6.610.313.53.43.53.2-3.2-3.2-3.23.13.43.63.43.1-3.1-3.13.0-2.93.0-3.7-2.5
Bone: trabecular spacing2.43.14.5-1.9-1.9-1.81.81.81.7-1.7-1.9-2.0-1.9-1.71.81.7-1.61.6-1.62.11.2
Bone: trabecular thickness0.10.10.1-0.3-0.3-0.30.30.30.3-0.3-0.3-0.2-0.3-0.30.30.3-0.30.3-0.30.0-0.3
Bone: trabecular tissue density0.10.10.1-0.2-0.2-0.30.30.30.3-0.4-0.2-0.1-0.2-0.30.40.3-0.40.4-0.4-0.2-0.2
Water consumed over 24 hours0.00.00.30.20.20.1-0.1-0.1-0.10.10.20.20.20.10.0-0.10.0-0.00.0-0.5-0.5
Number of responses in last shaping day0.10.10.60.00.00.1-0.1-0.2-0.20.30.20.00.20.1-0.3-0.40.5-0.40.40.3-0.7