Hub : Genes

Emx2os

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Emx2os 0.3 0.13 2.3e-07 0.11 0.11 0.12 0.12 1.9e-06 3.1e-06 9.6e-07 1.1e-06
2 Eye mRNA stability Emx2os 0.71 0.14 6.8e-05 0.06 0.17 0.18 0.2 4.8e-02 1.4e-03 1.2e-03 5.4e-04
3 Adipose mRNA stability Emx2os 0.19 0.07 0.0e+00 0.15 0.14 0.14 0.15 2.3e-16 7.3e-15 2.9e-15 1.9e-16
4 pVTA gene expression Emx2os 0.25 0.13 7.0e-09 0.12 0.09 0.09 0.1 1.0e-09 1.2e-07 5.7e-08 2.7e-08
5 BLA gene expression Emx2os 0.38 0.12 3.9e-14 0.21 0.2 0.2 0.2 3.7e-11 4.0e-11 8.3e-11 4.3e-11
6 Adipose intron excision ratio chr1_268557371_268612388 0.03 0.02 4.8e-03 0.01 0.01 0 0.01 1.7e-02 3.2e-02 3.1e-01 2.1e-02
7 PL gene expression Emx2os 0.43 0.13 0.0e+00 0.31 0.27 0.3 0.32 4.9e-34 7.0e-30 2.3e-33 5.6e-35
8 PL mRNA stability Emx2os 0.22 0.09 2.9e-12 0.12 0.1 0.12 0.12 8.7e-13 1.9e-11 3.0e-13 2.8e-13
9 IC gene expression Emx2os 0.57 0.11 0.0e+00 0.39 0.35 0.35 0.39 1.1e-17 2.2e-15 1.9e-15 2.6e-17
10 NAcc mRNA stability Emx2os 0.07 0.03 5.8e-08 0.07 0.06 0.06 0.07 1.6e-10 5.1e-09 6.2e-09 2.9e-10
11 NAcc intron excision ratio chr1_268551133_268612388 0.03 0.02 1.5e-03 0.01 0.02 0.01 0.01 1.0e-02 8.8e-04 3.2e-03 4.8e-03
12 Brain mRNA stability Emx2os 0.26 0.1 1.4e-14 0.16 0.17 0.17 0.17 5.0e-15 2.6e-15 1.8e-15 2.5e-15
13 Brain gene expression Emx2os 0.37 0.1 0.0e+00 0.29 0.3 0.29 0.3 1.1e-27 1.8e-28 1.4e-27 2.7e-28
14 NAcc gene expression Emx2os 0.38 0.12 0.0e+00 0.26 0.26 0.26 0.27 1.4e-39 2.9e-39 2.7e-39 2.4e-40
15 OFC gene expression Emx2os 0.6 0.16 3.4e-05 0.17 0.15 0.17 0.2 9.3e-05 1.8e-04 8.6e-05 1.6e-05
16 Brain intron excision ratio chr1_268551133_268612388 0.05 0.03 9.4e-04 0.02 0.02 0.02 0.01 6.9e-03 7.3e-03 5.4e-03 1.8e-02
17 pVTA intron excision ratio chr1_268557371_268612388 0.1 0.05 3.9e-06 0.06 0.07 0.06 0.07 3.0e-05 4.2e-06 9.7e-06 3.5e-06
18 OFC mRNA stability Emx2os 0.32 0.15 1.2e-03 0.03 0.1 0.06 0.04 7.3e-02 2.1e-03 1.6e-02 5.0e-02
19 Adipose gene expression Emx2os 0.18 0.08 8.3e-16 0.14 0.14 0.16 0.14 1.9e-15 7.7e-15 3.0e-17 1.3e-15
20 IC intron excision ratio chr1_268551133_268612388 0.09 0.07 5.6e-03 0 0.02 0.02 0 3.1e-01 3.5e-02 3.5e-02 3.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.12.06.62.2-2.4-1.61.11.41.4-1.4-1.41.21.2-2.61.0-0.8-0.8-0.71.9-0.20.3-0.5-1.3
Area under the delay curve1.21.85.51.3-1.4-1.21.00.91.2-1.1-1.11.21.10.31.3-1.6-1.4-1.9-1.1-1.2-2.32.10.5
BMI with tail15.052.5104.610.2-8.8-9.18.58.48.3-8.3-8.38.58.3-5.27.7-7.5-7.4-6.23.1-6.0-2.52.90.6
BMI without tail6.434.365.38.1-6.7-7.37.06.86.8-6.7-6.76.96.9-4.16.3-6.1-6.1-5.02.7-4.9-1.72.40.6
Body weight10.947.5103.310.2-9.6-8.67.87.97.7-7.8-7.87.67.7-6.36.9-6.9-6.6-5.73.7-4.8-2.12.0-0.9
Weight adjusted by age1.44.27.32.7-1.7-2.42.62.52.1-2.6-2.62.62.0-1.22.2-2.6-2.0-1.51.5-2.1-0.60.70.3
Bone surface0.81.65.01.9-2.0-1.51.21.31.2-1.3-1.31.21.1-2.20.9-0.7-0.8-0.71.9-0.30.5-0.5-0.9
Bone volume1.83.78.52.9-2.9-2.42.02.12.1-2.2-2.22.02.0-2.11.8-1.7-1.7-1.61.4-1.1-0.50.4-0.5
Breakpoint value in progressive ratio session0.20.33.10.6-1.8-0.1-0.0-0.1-0.10.20.3-0.3-0.1-0.7-0.3-0.00.2-0.2-0.80.6-0.80.2-0.9
Number of licking bursts0.30.93.3-0.1-0.60.6-0.6-0.5-0.70.50.6-0.8-0.7-1.8-0.91.01.00.61.21.31.2-1.2-1.6
Context. condit. distance diff. score0.20.21.6-0.20.30.00.00.1-0.1-0.1-0.10.40.2-0.20.00.1-0.10.50.8-0.21.2-1.00.2
Locomotion velocity, session 10.30.31.6-0.71.31.0-0.5-0.4-0.60.40.4-0.5-0.60.4-0.40.40.50.50.10.30.0-0.2-0.3
Locomotion distance, session 10.30.43.4-0.81.80.5-0.2-0.2-0.50.10.1-0.4-0.61.0-0.10.2-0.00.2-0.2-0.10.20.51.0
Locomotion velocity, session 20.91.13.9-1.72.01.0-0.8-0.8-1.00.90.9-1.1-1.01.1-0.90.90.81.1-0.20.61.3-0.50.9
Locomotion distance, session 20.81.22.11.00.4-1.41.41.41.2-1.4-1.30.91.10.11.2-1.1-1.2-0.80.4-1.00.30.81.3
Locomotion velocity, session 30.30.42.4-0.91.60.9-0.4-0.4-0.70.30.3-0.4-0.70.7-0.30.40.40.5-0.40.20.4-0.20.3
Locomotion distance, session 30.30.42.4-0.31.60.10.50.60.3-0.7-0.70.30.30.90.6-0.4-0.4-0.2-0.1-0.60.20.30.9
Stereotopy head waving bouts, day 30.30.40.8-0.80.60.5-0.7-0.7-0.70.80.8-0.6-0.60.9-0.60.40.4-0.0-0.90.2-0.50.40.6
Stereotopy head waving duration, day 30.70.81.8-1.00.30.7-1.3-1.2-1.01.31.3-1.2-1.00.3-1.10.91.00.3-0.70.9-0.20.10.0
Locomotion velocity, session 70.30.41.00.50.0-0.60.80.80.9-0.7-0.60.61.0-0.70.6-0.5-0.5-0.10.6-0.30.8-0.1-0.1
Locomotion distance, session 70.70.82.00.8-0.1-1.11.41.31.2-1.2-1.21.01.1-0.21.0-0.9-1.0-0.10.4-0.80.90.00.7
Stereotopy head waving bouts, day 70.20.21.30.3-0.4-0.10.20.2-0.1-0.1-0.10.3-0.1-0.20.2-0.3-0.3-1.2-0.5-0.3-1.11.0-0.0
Stereotopy head waving duration, day 70.30.32.1-0.0-0.80.4-0.4-0.5-0.60.50.5-0.3-0.5-0.2-0.30.20.3-0.8-0.80.3-1.40.7-0.6
Locomotion velocity, session 81.82.25.2-1.71.51.6-1.3-1.5-1.61.41.4-1.0-1.4-0.5-1.51.71.51.61.21.12.2-2.3-0.7
Locomotion distance, session 80.71.07.6-0.81.60.5-0.1-0.1-0.50.20.2-0.1-0.3-0.6-0.40.70.41.31.90.32.8-1.70.2
Degree of sensitization distance0.30.42.00.8-1.4-0.80.50.40.5-0.2-0.20.50.5-1.10.1-0.2-0.30.30.6-0.10.7-0.5-0.5
Degree of sensitization stereotypy0.60.72.11.1-1.0-0.40.80.70.4-0.7-0.70.90.5-1.10.7-0.7-0.6-1.50.2-0.5-1.10.9-0.7
Conditioned locomotion0.10.20.5-0.5-0.20.4-0.6-0.6-0.40.60.6-0.1-0.30.4-0.30.30.2-0.1-0.70.0-0.50.2-0.1
Cocaine response after cond. corrected1.32.07.2-2.22.60.9-1.3-1.3-1.01.31.3-1.0-1.02.7-0.80.80.71.5-0.80.01.2-0.22.2
Cocaine response after cond. not corrected2.43.58.0-2.82.81.8-2.0-1.9-1.91.91.9-1.8-1.92.5-1.61.61.52.3-1.00.91.7-0.91.4
Cocaine response before conditioning1.31.63.7-0.7-0.01.7-1.1-1.0-1.51.01.0-1.5-1.5-0.9-1.31.21.41.40.11.70.7-1.4-1.9
Saline control response0.30.41.9-0.11.40.10.30.50.3-0.5-0.60.40.20.80.5-0.4-0.4-0.6-0.3-0.7-0.81.10.6
Bone: connectivity density0.40.73.31.0-1.1-0.70.30.60.6-0.6-0.60.40.4-1.80.2-0.0-0.10.11.70.30.8-0.8-1.2
Bone: cortical apparent density1.92.913.1-2.93.62.2-1.6-1.7-1.41.61.6-1.4-1.22.6-1.21.31.11.2-1.50.40.6-0.11.2
Bone: cortical area4.37.013.73.7-3.6-3.23.02.93.1-2.9-2.93.02.8-3.42.5-2.2-2.4-2.42.4-1.6-0.10.2-0.8
Bone: cortical porosity0.10.10.80.4-0.9-0.2-0.1-0.0-0.10.10.20.0-0.1-0.5-0.10.1-0.10.0-0.30.2-0.0-0.2-0.4
Bone: cortical porosity0.40.42.61.1-1.6-0.70.40.40.3-0.3-0.30.40.3-1.30.2-0.3-0.4-0.40.30.1-0.2-0.1-0.8
Bone: cortical thickness4.47.311.43.3-2.3-3.13.33.23.3-3.2-3.23.43.1-2.82.8-2.4-2.7-2.42.5-2.20.30.6-0.1
Bone: cortical thickness5.16.210.32.8-1.7-3.13.12.93.1-2.9-2.82.83.2-1.12.7-2.7-2.7-2.70.8-2.4-1.11.91.0
Bone: cortical tissue density2.23.513.9-3.13.72.4-1.8-1.9-1.61.91.9-1.6-1.52.7-1.41.51.31.5-1.50.60.7-0.31.1
Condit. Reinf. active minus inactive responses0.70.82.3-0.71.10.7-0.6-0.6-0.40.70.7-0.7-0.5-0.5-0.80.80.91.21.30.81.5-1.4-0.6
Condit. Reinf. active-inactive response ratio1.61.82.7-1.31.31.3-1.4-1.4-1.11.51.5-1.6-1.10.0-1.51.51.51.60.81.41.3-1.6-0.6
Condit. Reinf. active responses0.81.15.71.1-0.2-0.91.00.91.1-0.9-0.80.71.0-1.90.5-0.5-0.40.02.4-0.11.2-1.0-0.8
Condit. Reinf. inactive responses2.02.66.12.1-1.3-1.82.01.81.8-1.8-1.81.81.6-2.51.4-1.4-1.3-1.12.3-0.90.5-0.1-0.7
Incentive salience index mean0.30.42.2-0.11.1-0.10.10.20.4-0.1-0.0-0.10.3-0.4-0.10.20.20.81.40.21.5-1.0-0.1
Condit. Reinf. lever presses0.20.41.10.50.6-0.70.80.81.0-0.6-0.50.50.8-0.00.5-0.6-0.50.30.6-0.50.7-0.10.4
Condit. Reinf. active minus inactive responses0.30.42.60.8-1.6-0.40.10.10.2-0.1-0.0-0.10.3-1.3-0.20.10.2-0.20.90.6-0.3-0.5-1.2
Condit. Reinf. active-inactive response ratio0.30.52.31.1-1.5-0.80.60.60.7-0.6-0.50.60.7-1.00.5-0.5-0.4-0.70.6-0.2-0.40.0-0.6
Condit. Reinf. active responses0.70.95.41.6-2.3-0.80.60.70.6-0.7-0.70.20.7-1.90.3-0.4-0.2-0.60.90.4-0.5-0.2-1.4
Condit. Reinf. inactive responses0.30.42.11.1-1.4-0.50.40.60.4-0.6-0.6-0.10.5-1.10.2-0.3-0.2-0.30.10.4-0.30.1-0.8
Condit. Reinf. lever presses0.71.03.11.6-1.8-1.20.91.11.0-1.1-1.10.61.1-1.30.8-0.7-0.7-1.00.6-0.1-0.40.0-0.6
Condit. Reinf. lever reinforcers received0.40.63.11.0-1.8-0.40.20.30.2-0.3-0.3-0.10.3-1.7-0.10.00.2-0.21.00.7-0.0-0.6-1.5
Conditioned reinforcement - actives0.20.83.8-1.41.90.9-0.6-0.6-0.60.60.7-0.7-0.61.6-0.40.70.40.3-1.20.20.10.61.0
Conditioned reinforcement - inactives0.30.81.4-1.10.11.2-1.1-1.1-1.01.11.1-1.1-1.10.1-1.01.21.00.5-0.71.1-0.2-0.2-0.8
Conditioned locomotion0.71.06.2-1.62.51.2-0.6-0.6-0.90.70.7-0.8-0.81.7-0.50.70.50.4-0.80.10.20.61.1
Patch foraging indifference point 0 sec1.95.410.23.2-2.3-2.72.82.82.7-2.8-2.82.52.8-2.12.4-2.3-2.2-2.31.9-1.6-0.71.10.0
Patch foraging indifference point AUC0.30.81.71.1-0.9-0.60.70.90.9-1.0-1.01.30.7-0.90.9-0.6-0.7-1.30.3-0.8-1.00.4-0.7
Delay disc. indifference point, 0s delay0.70.81.50.8-0.3-1.00.80.80.9-1.0-1.01.20.80.21.1-1.1-1.1-1.0-0.1-1.2-0.60.70.8
Delay disc. indifference point, 16s delay1.11.64.71.3-1.2-1.11.10.91.2-1.0-1.01.11.20.21.2-1.5-1.3-1.7-0.7-1.1-2.22.10.5
Delay disc. indifference point, 2s delay0.70.83.40.00.1-0.30.20.10.2-0.3-0.30.60.21.50.6-0.9-0.8-0.9-1.8-1.1-1.51.51.3
Delay disc. indifference point, 24s delay0.81.33.11.4-1.5-1.10.90.91.2-1.0-1.01.11.0-0.51.1-1.2-1.0-1.70.1-0.8-1.81.7-0.1
Delay disc. indifference point, 4s delay0.91.03.80.8-1.2-0.70.50.60.6-0.7-0.70.80.50.60.9-1.1-0.9-1.5-0.8-0.9-1.91.90.6
Delay disc. indifference point, 8s delay0.61.14.20.9-1.1-0.80.70.60.8-0.7-0.70.80.80.30.9-1.1-1.0-1.5-1.2-0.9-2.11.80.3
Indifference point function ln k0.00.10.80.00.3-0.30.40.2-0.1-0.00.0-0.20.2-0.0-0.1-0.1-0.10.60.50.10.9-0.40.5
Indifference point function log k0.00.10.80.00.3-0.30.40.2-0.1-0.00.0-0.20.2-0.0-0.1-0.1-0.10.60.50.10.9-0.40.5
Patch foraging total patch changes 0 sec2.16.111.73.4-2.6-2.93.03.02.8-2.9-2.92.62.9-2.42.5-2.5-2.3-2.42.0-1.7-0.71.1-0.1
Patch foraging total patch changes 12 sec3.04.08.22.9-2.2-2.12.32.42.3-2.4-2.42.32.1-2.22.1-1.8-1.8-2.01.7-1.3-0.70.7-0.6
Patch foraging total patch changes 18 sec1.02.55.12.3-2.0-1.41.71.71.7-1.8-1.81.81.7-1.81.5-1.4-1.2-1.61.3-1.0-1.20.4-1.0
Patch foraging total patch changes 24 sec0.30.93.11.4-1.5-0.60.90.90.7-0.9-1.01.00.6-1.80.7-0.7-0.6-1.10.9-0.3-0.70.1-1.1
Patch foraging total patch changes 6 sec2.54.38.72.9-2.4-2.22.12.42.4-2.4-2.42.12.3-2.91.9-1.8-1.5-2.12.2-1.0-0.60.6-1.1
Patch foraging time to switch 0 sec1.14.27.2-2.71.22.1-2.4-2.7-2.22.62.6-2.7-2.51.8-2.31.82.02.1-1.41.90.5-0.90.2
Patch foraging water rate 0 sec1.76.411.13.3-1.8-2.93.13.12.8-3.1-3.13.12.9-2.12.8-2.5-2.5-2.61.8-2.2-0.81.30.0
Patch foraging water rate 12 sec0.72.75.32.3-1.7-1.71.91.91.7-1.9-1.92.11.7-2.31.7-1.5-1.4-1.71.5-1.2-0.40.3-0.7
Patch foraging water rate 18 sec1.12.54.31.9-0.7-2.01.82.11.8-1.9-1.91.71.9-0.31.8-1.8-1.8-1.40.1-1.6-0.41.41.1
Patch foraging water rate 24 sec3.55.08.92.7-1.6-3.02.62.72.6-2.7-2.62.22.4-0.32.4-2.6-2.4-2.3-0.2-2.0-1.21.91.5
Patch foraging water rate 6 sec1.82.74.32.0-1.0-2.12.11.91.8-1.9-1.92.01.8-0.51.9-1.9-1.9-1.60.1-1.7-0.81.30.7
Seeking ratio, delayed vs. immediate footshock2.02.96.4-2.52.31.8-1.9-1.9-1.51.81.8-1.8-1.61.2-1.72.01.72.10.11.31.8-0.90.2
Distance traveled before self-admin0.71.57.9-1.12.50.2-0.10.10.2-0.0-0.10.00.32.80.4-0.5-0.5-0.3-2.0-1.0-0.71.52.3
Distance traveled after self-admin0.61.16.1-1.21.90.6-0.5-0.2-0.20.30.3-0.4-0.22.5-0.00.1-0.10.1-2.2-0.4-0.71.21.6
Extensor digitorum longus weight1.77.014.73.8-2.8-2.73.23.13.0-3.1-3.13.03.1-1.42.9-2.8-2.8-2.30.5-2.2-2.01.6-0.4
Bone: elastic displacement0.50.63.10.10.2-0.40.50.70.5-0.6-0.50.40.50.90.6-0.7-0.6-1.0-1.3-0.7-1.31.80.8
Bone: elastic work2.93.86.71.6-0.3-2.12.22.22.1-2.2-2.12.02.10.72.1-2.2-2.2-2.3-0.8-2.1-1.62.61.8
Bone: endosteal estimation0.30.73.51.4-1.9-1.30.90.80.7-0.8-0.80.60.7-1.10.6-0.7-0.6-0.60.5-0.3-0.3-0.1-0.3
Bone: endosteal perimeter0.81.97.02.0-2.6-1.81.41.31.4-1.3-1.31.21.3-0.81.3-1.3-1.3-1.7-0.3-0.9-1.40.70.1
Epididymis fat weight7.738.9110.49.4-10.5-7.66.76.86.7-6.8-6.86.86.5-7.15.9-5.8-5.5-4.73.6-3.7-1.50.8-2.2
Delta time in closed arm before/after self-admin0.30.30.9-0.60.90.2-0.3-0.3-0.40.30.3-0.3-0.20.4-0.30.20.30.81.0-0.01.0-0.80.6
Delta time in open arm before/after self-admin1.51.84.7-0.5-1.21.1-1.4-1.3-1.21.31.3-1.4-1.4-1.3-1.51.51.51.4-0.01.90.7-1.4-2.2
Diff in mean of infusions in LGA sessions0.10.11.10.3-1.00.1-0.0-0.0-0.30.00.0-0.0-0.4-0.5-0.00.10.0-0.4-0.50.2-0.7-0.2-0.5
Delay discount exponential model param1.41.96.2-1.31.51.2-1.0-0.9-1.11.11.1-1.2-1.0-0.4-1.31.61.42.01.21.22.5-2.3-0.6
Extinction: sum of active levers before priming0.20.41.61.0-1.1-0.40.50.50.5-0.4-0.40.40.6-0.10.4-0.7-0.4-0.4-0.5-0.2-1.30.3-0.6
Active lever presses in extinction session 60.30.31.60.7-1.3-0.80.50.30.4-0.3-0.30.40.3-0.20.4-0.7-0.6-0.7-0.8-0.3-0.90.60.2
Bone: final force3.96.411.33.3-2.8-3.42.92.73.1-2.7-2.72.93.1-2.62.4-2.4-2.5-2.42.2-1.8-0.10.70.0
Bone: final moment3.45.49.83.1-2.8-3.12.72.52.8-2.4-2.52.72.7-2.52.2-2.1-2.3-2.12.0-1.60.00.6-0.1
Food consumed during 24 hour testing period0.20.31.7-0.60.30.3-0.4-0.5-0.60.60.6-0.4-0.8-0.1-0.50.70.40.90.20.41.3-0.70.2
Glucose2.13.310.52.6-3.2-2.11.92.11.8-2.0-2.01.51.6-1.31.7-1.7-1.6-2.1-0.4-0.8-1.51.2-0.3
Heart weight3.76.012.43.5-3.4-3.02.82.62.6-2.6-2.62.92.6-3.22.3-2.2-2.2-1.72.4-1.50.3-0.1-0.8
Delay discount hyperbolic model param1.51.96.5-1.31.51.1-0.9-0.9-1.11.01.0-1.2-1.0-0.6-1.31.61.42.01.41.32.5-2.4-0.7
Intermittent access intake day 1-15 change0.10.42.9-0.60.60.5-0.4-0.4-0.40.40.4-0.6-0.51.4-0.2-0.00.30.1-1.70.0-0.80.60.7
Intermittent access intake escalation0.10.41.9-0.70.50.7-0.6-0.5-0.70.60.6-0.7-0.61.1-0.50.30.50.3-1.40.3-0.50.30.4
Intermittent access intake escalation 20.10.20.6-0.60.40.4-0.5-0.4-0.40.50.5-0.7-0.30.7-0.40.30.50.5-0.70.30.1-0.00.4
Intermitt. access day 1 inactive lever presses0.11.13.8-0.0-1.60.6-0.9-0.9-0.81.01.0-0.9-1.0-1.4-1.11.11.10.8-0.01.40.2-1.0-1.9
Intermitt. access day 15 inactive lever presses0.10.31.60.9-1.3-0.60.40.40.5-0.5-0.50.30.5-0.80.3-0.5-0.3-0.80.3-0.1-0.70.3-0.4
Intermitt. access escalation Index0.31.11.9-1.00.41.3-1.3-1.1-1.11.21.2-1.4-1.10.3-1.11.21.21.3-0.41.20.6-0.8-0.5
Intermittent access day 1 total infusions0.10.20.6-0.60.60.5-0.3-0.3-0.30.40.4-0.3-0.40.8-0.30.20.20.2-0.40.1-0.40.20.2
Intermittent access day 15 total infusions0.30.72.2-1.00.71.0-0.7-0.7-0.90.80.8-0.9-0.91.5-0.60.40.60.3-1.50.3-0.90.60.5
Intermittent access terminal intake (last 3 days)0.20.31.6-0.50.20.5-0.4-0.4-0.50.50.5-0.5-0.41.1-0.30.10.3-0.1-1.30.1-1.00.80.4
Intermittent access total infusions0.20.20.7-0.60.60.6-0.3-0.4-0.50.40.5-0.5-0.40.8-0.30.30.40.1-0.70.2-0.60.50.1
Intermittent access day 1 locomotion0.40.73.9-0.41.10.10.30.20.1-0.1-0.10.10.12.00.3-0.6-0.5-0.6-1.1-0.8-1.51.61.4
Intermittent access day 15 total locomotion0.10.42.80.4-0.8-0.10.30.30.3-0.2-0.20.20.20.20.3-0.6-0.2-1.0-0.5-0.3-1.71.3-0.2
Intermittent access total locomotion0.60.72.6-0.10.8-0.10.50.50.5-0.5-0.50.30.51.60.6-0.8-0.6-0.8-0.7-0.8-1.41.41.2
Intermittent access standard deviation0.10.43.30.0-0.60.2-0.1-0.2-0.30.20.3-0.2-0.10.6-0.0-0.30.1-0.7-1.60.0-1.81.0-0.1
Left kidney weight2.923.339.86.3-4.2-6.15.95.95.8-5.8-5.85.75.9-3.25.3-5.1-5.1-3.82.9-4.2-0.41.61.2
Right kidney weight3.726.044.06.6-4.6-6.66.36.36.1-6.2-6.15.96.0-2.65.6-5.5-5.5-3.92.2-4.6-0.62.01.7
Cocaine induced anxiety0.20.64.8-1.22.20.7-0.6-0.6-0.40.60.5-0.6-0.40.8-0.50.70.60.40.50.30.9-0.10.7
Post-drug Anxiety0.30.42.70.20.4-0.20.10.20.4-0.2-0.2-0.00.2-1.2-0.00.10.30.21.70.31.1-0.9-0.6
Baseline Anxiety0.50.85.01.3-2.2-0.70.30.40.5-0.4-0.40.10.3-1.90.1-0.2-0.0-0.10.70.50.0-0.8-1.5
Tail length0.00.21.00.5-1.0-0.00.10.30.4-0.2-0.2-0.10.3-0.50.1-0.1-0.1-0.3-0.30.3-0.60.2-0.9
Length with tail0.62.57.82.4-2.8-1.61.51.71.6-1.6-1.71.21.6-2.41.2-1.2-1.0-1.21.3-0.3-0.4-0.0-1.5
Length without tail0.84.315.63.3-4.0-2.21.92.11.9-2.1-2.11.61.8-3.51.5-1.5-1.4-1.52.0-0.3-0.4-0.2-1.9
Times rat made contact with spout0.20.20.60.6-0.6-0.80.40.60.6-0.6-0.60.30.7-0.30.4-0.5-0.5-0.10.2-0.20.3-0.00.2
Lifetime Intake0.20.20.8-0.70.90.7-0.4-0.5-0.50.50.5-0.5-0.50.7-0.40.30.40.2-0.50.2-0.30.30.1
Liver weight, left6.811.824.14.9-4.2-4.24.14.03.7-3.9-3.94.13.6-2.73.6-3.5-3.6-3.01.6-2.8-1.31.40.0
Liver weight, right4.07.012.43.5-2.4-3.53.43.33.2-3.3-3.22.93.0-0.92.9-2.9-3.0-1.80.7-2.3-0.51.21.1
Locomotor activity0.00.10.3-0.30.50.5-0.2-0.1-0.20.10.1-0.2-0.00.5-0.10.10.20.2-0.50.0-0.20.0-0.0
Locomotor testing distance0.20.42.6-0.91.60.6-0.2-0.1-0.10.10.1-0.20.21.5-0.10.10.10.4-0.7-0.3-0.00.10.8
Locomotor testing rearing0.20.62.60.00.6-0.20.30.60.5-0.5-0.50.30.71.60.5-0.6-0.5-0.5-1.4-0.8-1.11.01.1
Locomotion in novel chamber0.20.32.5-0.10.4-0.70.30.20.4-0.3-0.30.50.40.70.6-0.2-0.50.1-0.4-0.70.9-0.11.6
Locomotion in novel chamber post-restriction0.41.24.00.50.7-1.01.11.10.8-1.1-1.11.20.90.91.3-1.0-1.4-1.3-0.9-1.5-0.40.82.0
Fecal boli incidents, locomotor time 10.00.10.40.20.1-0.00.20.30.2-0.2-0.1-0.20.4-0.6-0.1-0.10.2-0.30.20.30.0-0.2-0.4
Change in fecal boli incidents, locomotor task0.40.42.30.8-0.6-0.70.70.50.4-0.6-0.70.90.4-0.90.5-0.4-0.50.01.5-0.50.7-0.2-0.1
Time >=10cm from walls, locomotor time 10.10.10.4-0.30.40.3-0.3-0.3-0.20.30.3-0.2-0.1-0.3-0.40.40.20.30.30.30.6-0.3-0.3
Bouts of movement, locomotor time 10.10.21.1-0.0-1.00.3-0.3-0.4-0.50.40.4-0.1-0.50.1-0.20.20.10.30.20.2-0.6-0.1-0.7
Total resting periods, locomotor time 10.10.10.50.1-0.70.2-0.1-0.2-0.30.20.20.1-0.30.20.00.0-0.00.30.2-0.0-0.5-0.1-0.4
Rest time, locomotor task time 10.40.71.40.70.3-0.91.01.01.0-1.0-1.01.01.20.00.9-0.8-0.9-0.30.7-0.90.40.10.8
Distance moved, locomotor task time 10.10.11.0-0.2-0.30.2-0.3-0.3-0.30.30.3-0.2-0.50.4-0.2-0.10.1-0.3-1.00.0-0.80.50.1
Vertical activity count, locomotor time 10.00.20.90.30.1-0.10.40.40.3-0.4-0.40.40.20.40.5-0.7-0.3-0.7-0.5-0.6-1.00.80.4
Time >=10cm from walls, locomotor time 20.30.93.31.2-0.2-1.01.21.11.1-1.0-1.00.91.1-1.40.7-0.7-0.6-0.61.8-0.50.6-0.1-0.2
Bouts of movement, locomotor time 20.41.53.1-1.60.41.3-1.4-1.6-1.51.31.3-1.3-1.51.7-1.01.10.81.0-1.80.8-0.4-0.00.4
Total resting periods, locomotor time 20.31.43.6-1.50.41.3-1.3-1.5-1.41.21.2-1.2-1.41.9-1.00.90.70.9-1.90.7-0.60.20.4
Rest time, locomotor task time 20.10.21.1-0.40.50.2-0.3-0.20.00.10.1-0.20.31.1-0.0-0.2-0.20.1-0.6-0.1-0.60.70.4
Distance moved, locomotor task time 20.10.20.60.5-0.1-0.40.60.40.2-0.4-0.40.60.0-0.80.3-0.2-0.2-0.30.5-0.30.5-0.20.0
Vertical activity count, locomotor time 20.10.20.80.50.0-0.30.60.60.3-0.5-0.50.50.3-0.80.4-0.3-0.1-0.20.9-0.30.4-0.3-0.2
Light reinforcement 10.10.41.00.11.0-0.30.70.60.5-0.6-0.70.90.40.60.7-0.4-0.7-0.10.1-1.00.30.41.0
Light reinforcement 20.20.42.5-0.91.60.9-0.4-0.5-0.70.30.20.1-0.80.7-0.10.50.10.7-0.3-0.20.8-0.10.4
Bone: marrow area0.40.93.81.6-2.0-1.41.00.90.8-0.9-0.90.80.8-1.20.8-0.8-0.8-0.70.5-0.3-0.3-0.0-0.3
Bone: maximum diameter1.32.713.32.5-3.7-1.91.51.41.7-1.4-1.41.51.5-2.41.2-1.2-1.1-1.50.8-0.5-0.7-0.1-1.2
Bone: maximum force2.34.58.32.8-2.2-2.92.42.32.6-2.3-2.32.42.4-2.52.0-1.9-2.0-1.82.4-1.40.50.2-0.1
Bone: maximum moment1.93.66.72.6-2.3-2.62.12.02.2-2.0-2.02.12.1-2.51.7-1.6-1.7-1.52.2-1.10.70.1-0.2
Mean time between licks in bursts0.63.36.0-1.3-0.21.7-2.0-1.9-1.91.91.9-2.3-2.0-0.7-2.12.12.12.30.32.41.6-1.9-1.7
Mean num. licks in bursts0.61.73.90.70.3-1.31.01.11.3-1.2-1.21.11.41.81.4-1.5-1.6-0.8-1.2-1.6-1.11.52.0
Cd content in liver0.50.53.3-1.11.80.2-0.4-0.2-0.60.30.2-0.3-0.50.7-0.30.30.10.40.1-0.11.5-0.41.3
Co content in liver0.40.51.50.30.7-0.80.70.80.5-0.9-0.90.70.40.00.8-0.7-0.7-0.50.4-0.80.70.51.2
Cu content in liver0.20.30.6-0.80.20.4-0.5-0.7-0.50.70.7-0.5-0.70.6-0.40.30.30.1-0.70.30.00.40.6
Fe content in liver0.81.05.40.6-1.50.1-0.2-0.2-0.10.10.1-0.1-0.3-2.3-0.40.40.60.31.70.90.9-1.6-2.0
K content in liver0.70.72.8-0.9-0.10.8-1.1-0.8-0.90.90.9-1.0-0.91.0-0.60.50.70.3-1.70.7-0.70.50.2
Mg content in liver0.91.07.2-0.60.00.3-0.6-0.4-0.60.50.5-0.5-0.61.9-0.1-0.10.1-0.3-2.7-0.1-1.51.71.1
Mn content in liver0.40.50.90.7-0.4-0.60.80.70.4-0.6-0.60.70.50.50.8-0.7-0.8-0.6-1.0-0.8-0.90.70.6
Na content in liver0.70.84.20.6-1.1-0.30.30.70.0-0.6-0.50.30.11.00.7-0.8-0.6-0.7-2.0-0.5-1.71.40.7
Rb content in liver0.30.41.5-0.4-0.20.5-0.5-0.6-0.80.70.7-0.8-0.70.4-0.50.30.3-0.0-1.20.6-0.90.4-0.1
Se content in liver0.50.61.3-0.70.50.9-0.8-0.7-1.10.70.7-0.6-1.1-0.6-0.80.71.10.70.50.70.8-1.0-0.7
Sr content in liver1.21.03.6-1.41.90.9-1.2-1.0-1.11.01.0-0.6-1.01.7-0.80.80.60.9-0.3-0.00.30.01.1
Zn content in liver0.81.06.0-0.91.30.4-0.4-0.2-0.50.20.2-0.4-0.42.50.1-0.2-0.1-0.1-2.1-0.5-0.91.21.8
Bone: minimum diameter2.34.48.82.9-3.0-2.52.42.32.4-2.3-2.32.41.9-2.32.1-1.9-2.0-2.11.3-1.4-0.70.6-0.6
Time in familiar zone, hab. session 12.52.74.21.7-1.0-1.91.81.71.7-1.8-1.91.91.70.52.0-1.9-2.1-1.7-0.9-1.9-1.51.41.3
Time in novel zone, hab. session 12.73.05.1-1.61.02.2-1.9-1.8-1.81.81.8-2.1-1.7-0.8-2.02.02.21.60.92.11.0-1.4-2.0
Total zone transitions, hab. session 11.72.33.71.5-0.4-1.61.91.71.8-1.9-1.91.61.60.01.8-1.7-1.7-1.8-0.1-1.6-1.21.60.9
Total locomotion distance, hab. session 10.30.52.1-0.1-0.20.3-0.2-0.3-0.30.20.2-0.3-0.6-1.5-0.50.60.50.31.20.71.1-1.0-1.0
Locomotion velocity, hab. session 10.20.31.6-0.0-0.10.1-0.0-0.2-0.20.10.1-0.1-0.5-1.3-0.30.50.30.41.10.51.2-1.0-0.8
Time in familiar zone, hab. session 20.60.72.5-0.2-0.80.8-0.7-0.6-0.60.70.7-0.5-0.7-0.8-0.80.90.81.1-0.10.90.6-1.5-1.6
Time in novel zone, hab. session 20.40.51.60.20.8-0.60.60.60.5-0.6-0.70.40.50.70.7-0.7-0.6-0.80.0-0.8-0.51.21.3
Total zone transitions, hab. session 20.40.51.00.4-0.3-0.80.70.50.7-0.6-0.60.60.50.80.8-0.8-0.9-0.7-0.9-0.8-0.70.81.0
Total locomotion distance, hab. session 20.30.40.60.8-0.7-0.80.80.70.7-0.7-0.70.70.5-0.50.7-0.5-0.7-0.40.3-0.50.2-0.20.1
Locomotion velocity, hab. session 20.30.50.80.9-0.8-0.90.90.80.8-0.8-0.80.80.6-0.30.8-0.7-0.8-0.50.0-0.6-0.10.10.3
Novel to familiar place preference ratio0.91.24.0-0.50.41.0-0.9-1.0-1.10.90.8-0.6-0.9-1.4-1.01.11.00.92.00.91.1-1.4-1.4
Novelty place preference0.81.02.9-0.60.61.1-0.9-1.0-1.20.90.9-0.5-1.0-1.2-1.01.01.00.81.70.80.9-1.3-1.3
Time in novel zone, NPP test0.91.13.9-0.30.21.0-0.7-0.8-1.00.80.8-0.4-0.8-1.6-0.91.01.00.82.00.80.9-1.5-1.7
Total zone transitions, NPP test0.40.61.30.9-0.3-1.11.10.91.1-0.9-0.90.81.10.20.9-0.8-0.9-0.3-0.0-0.80.10.50.8
Total locomotion distance, NPP test0.20.31.90.50.0-0.50.60.50.4-0.4-0.30.50.3-0.90.3-0.1-0.30.11.4-0.21.1-0.60.0
Locomotion velocity, NPP test0.20.31.80.20.5-0.50.50.40.3-0.3-0.30.30.2-0.50.2-0.0-0.20.31.2-0.21.3-0.50.4
Intraocular pressure0.40.63.70.3-1.20.3-0.1-0.5-0.40.40.40.2-0.1-1.9-0.40.30.4-0.11.10.50.0-0.5-1.8
Delta distance traveled before/after self-admin0.10.10.90.3-0.3-0.00.10.20.2-0.2-0.1-0.00.10.40.1-0.2-0.2-0.2-0.9-0.0-0.90.4-0.0
Delta ambulatory time before/after self-admin0.10.10.70.5-0.8-0.10.10.20.2-0.2-0.20.10.10.10.2-0.1-0.3-0.3-0.60.0-0.90.3-0.3
Parametrial fat weight9.923.466.77.3-8.2-6.05.55.25.2-5.2-5.25.25.4-5.14.4-4.6-4.3-3.42.7-2.9-1.30.6-1.6
Pavlov. Cond. lever latency1.11.42.4-1.10.21.5-1.5-1.4-1.51.31.3-1.5-1.40.0-1.31.31.40.9-0.21.30.1-0.6-0.9
Pavlov. Cond. magazine entry latency0.20.30.70.5-0.8-0.70.50.40.6-0.4-0.40.80.50.00.6-0.5-0.7-0.2-0.2-0.60.2-0.00.4
Pavlov. Cond. change in total contacts1.31.42.31.4-1.2-1.41.41.41.5-1.3-1.21.51.3-0.01.4-1.4-1.5-0.9-0.4-1.3-0.50.70.5
Pavlov. Cond. index score0.81.01.81.1-0.9-1.31.21.11.3-1.0-1.01.31.10.01.2-1.1-1.2-0.7-0.2-1.1-0.20.40.6
Pavlov. Cond. latency score0.70.81.50.9-0.7-1.21.11.01.2-1.0-1.01.21.00.11.1-1.0-1.2-0.6-0.2-1.0-0.10.40.6
Pavlov. Cond. lever contacts1.01.22.31.2-0.9-1.51.31.21.4-1.1-1.11.31.2-0.01.3-1.3-1.4-1.0-0.3-1.2-0.50.80.8
Pavlov. Cond. magazine entry number0.30.41.1-0.71.01.0-0.7-0.6-0.90.50.5-0.8-0.8-0.3-0.70.70.80.40.50.70.2-0.2-0.5
Pavlov. Cond. intertrial magazine entries1.92.24.71.8-0.5-1.91.91.81.9-1.8-1.81.61.9-1.61.4-1.4-1.2-0.82.2-1.10.70.00.1
Pavlov. Cond. lever-magazine prob. diff.0.81.01.81.1-1.0-1.31.21.11.3-1.0-1.01.31.1-0.11.2-1.1-1.2-0.6-0.2-1.1-0.20.30.5
Pavlov. Cond. response bias0.50.61.40.7-0.8-1.20.90.81.1-0.7-0.60.91.00.30.8-0.9-1.0-0.6-0.5-0.9-0.20.40.8
Pavlov. Cond. lever latency0.30.42.5-0.31.6-0.10.30.30.4-0.3-0.30.40.41.30.4-0.5-0.4-0.2-0.2-0.9-0.20.81.3
Pavlov. Cond. magazine entry latency0.40.51.1-0.3-1.00.6-0.7-0.8-0.80.80.8-0.9-1.0-0.1-0.70.60.70.7-0.90.9-0.0-0.6-0.8
Pavlov. Cond. change in total contacts0.20.41.2-0.1-1.00.5-0.6-0.6-0.70.70.7-0.6-0.8-0.8-0.70.60.60.4-0.20.90.1-0.5-1.1
Pavlov. Cond. index score0.20.32.00.2-1.40.2-0.3-0.4-0.40.40.4-0.4-0.5-0.9-0.40.40.40.2-0.30.70.0-0.6-1.1
Pavlov. Cond. latency score0.20.41.80.1-1.30.2-0.4-0.5-0.50.40.4-0.5-0.6-0.8-0.50.50.50.4-0.30.80.1-0.7-1.0
Pavlov. Cond. lever contacts0.20.21.80.5-1.3-0.20.10.10.0-0.1-0.10.00.0-1.10.00.1-0.0-0.30.20.40.0-0.4-0.9
Pavlov. Cond. magazine entry number0.20.21.1-0.01.1-0.10.30.40.5-0.4-0.40.40.70.20.4-0.2-0.2-0.10.7-0.50.30.20.5
Pavlov. Cond. intertrial magazine entries1.02.33.81.9-1.1-1.71.91.81.6-1.8-1.81.91.9-0.81.7-1.5-1.6-1.41.0-1.5-0.40.60.4
Pavlov. Cond. lever-magazine prob. diff.0.20.21.60.2-1.30.1-0.2-0.3-0.30.30.3-0.4-0.5-0.7-0.40.30.30.1-0.40.7-0.1-0.4-0.9
Pavlov. Cond. response bias0.40.52.10.1-1.40.3-0.4-0.5-0.50.40.4-0.5-0.6-1.2-0.60.60.50.30.20.90.3-0.8-1.4
Time in closed arm before self-admin0.30.51.00.6-0.3-0.60.90.70.6-0.7-0.70.80.40.50.8-1.0-1.0-0.6-1.0-0.9-0.80.70.5
Time in closed arm after self-admin0.40.42.9-0.50.9-0.00.2-0.1-0.10.10.00.3-0.11.70.3-0.5-0.50.2-0.7-0.9-0.30.21.4
Time in open arm before self-admin1.21.43.3-1.81.81.5-1.3-1.3-1.21.31.3-1.0-1.20.2-1.31.61.40.70.60.90.8-0.4-0.4
Time in open arm after self-admin1.61.83.6-1.00.01.4-1.4-1.3-1.21.31.4-1.6-1.3-1.0-1.61.81.71.1-0.01.90.7-1.1-1.9
Bone: periosteal estimation2.25.311.23.3-3.4-3.12.72.52.5-2.5-2.52.52.4-2.72.2-2.0-2.1-2.01.8-1.4-0.20.2-0.4
Bone: periosteal perimeter3.57.016.53.7-4.1-3.32.92.93.0-2.9-2.92.72.9-2.12.6-2.6-2.5-2.80.7-1.8-1.61.1-0.2
Bone: post-yield work0.61.15.70.7-0.9-0.50.20.10.2-0.1-0.10.1-0.2-2.4-0.20.40.40.62.30.71.9-1.5-1.3
Progressive ratio test 1 active lever presses0.50.83.1-1.21.00.9-0.7-0.8-1.00.80.9-0.8-0.91.7-0.60.40.40.4-1.80.1-0.70.40.8
Progressive ratio test 1 breakpoint0.40.82.8-1.10.90.9-0.6-0.8-1.00.80.9-0.8-0.81.7-0.60.40.40.4-1.60.1-0.60.40.8
Progressive ratio test 1 inactive lever presses0.10.20.4-0.4-0.10.5-0.5-0.6-0.40.50.5-0.5-0.6-0.1-0.60.50.40.2-0.50.5-0.3-0.3-0.6
Progressive ratio test 2 active lever presses0.30.52.10.3-0.1-0.30.50.40.5-0.4-0.30.40.40.80.6-0.7-0.5-0.9-1.2-0.6-1.41.30.5
Progressive ratio test 2 breakpoint0.30.42.00.2-0.2-0.20.50.30.5-0.3-0.30.30.40.70.5-0.6-0.5-0.9-1.2-0.5-1.41.30.4
Progressive ratio test 2 inactive lever presses0.10.20.7-0.2-0.20.3-0.2-0.3-0.10.30.4-0.4-0.3-0.8-0.50.60.60.20.40.60.4-0.4-0.8
Incentive Sensitization - Responses0.30.92.51.0-0.9-0.80.90.91.2-0.8-0.80.81.00.00.9-1.0-0.8-1.3-0.7-0.7-1.61.50.1
Incentive Sensitization - Breakpoint0.40.82.50.9-0.9-0.70.80.81.1-0.8-0.80.80.9-0.00.9-0.9-0.7-1.3-0.6-0.6-1.61.5-0.1
Sum of active levers in priming session hrs 5-60.40.31.4-0.2-0.70.6-0.4-0.4-0.60.50.6-0.6-0.60.2-0.60.50.50.6-1.20.7-0.5-0.2-0.7
Progressive ratio1.13.15.7-2.21.52.2-2.0-1.9-2.31.91.9-2.1-2.40.4-2.12.21.91.0-0.61.70.8-1.0-0.5
Food seeking constrained by brief footshock1.31.73.6-1.71.51.9-1.6-1.5-1.81.41.3-1.3-1.90.6-1.31.41.20.5-0.71.0-0.0-1.0-0.5
Seeking ratio, punishment vs. effort0.61.42.51.0-0.1-1.11.11.11.4-1.2-1.21.41.40.81.5-1.6-1.4-0.9-0.7-1.5-1.21.00.8
Retroperitoneal fat weight13.460.0140.811.5-11.9-9.48.78.58.2-8.6-8.79.18.3-8.37.6-7.3-7.1-5.84.9-5.3-1.70.9-2.2
Reaction time number correct0.10.32.5-0.2-0.90.1-0.2-0.5-0.50.40.4-0.2-0.30.9-0.20.00.0-0.2-1.6-0.0-1.20.30.2
Reaction time mean minus median0.21.14.31.0-0.6-1.00.80.81.1-0.7-0.70.50.90.80.9-1.2-1.0-1.3-1.4-0.8-2.11.60.6
Reaction time mean minus median AUC0.42.69.40.8-0.3-1.00.90.91.0-0.8-0.80.61.02.31.2-1.6-1.5-1.6-3.1-1.4-2.92.81.8
Reaction time num false alarms0.61.02.51.00.2-1.31.31.11.6-1.2-1.31.11.3-0.21.1-1.0-1.1-0.60.8-1.00.40.20.8
Reaction time num false alarms AUC0.51.22.61.00.1-1.41.31.21.6-1.3-1.41.11.50.11.3-1.2-1.3-0.80.3-1.10.10.61.1
Reaction time trials correct on left0.10.32.5-0.2-0.90.1-0.2-0.5-0.50.40.4-0.2-0.30.9-0.20.00.0-0.2-1.6-0.0-1.20.30.2
Reaction time trials on left0.10.42.7-0.2-0.90.1-0.2-0.5-0.50.40.4-0.2-0.30.9-0.20.00.0-0.2-1.7-0.0-1.30.30.2
Reaction time mean0.61.37.8-0.30.10.1-0.2-0.1-0.10.20.2-0.4-0.02.30.1-0.5-0.3-0.8-2.8-0.4-2.51.91.1
Reaction time mean AUC0.71.610.1-0.40.20.1-0.2-0.1-0.00.20.2-0.4-0.02.60.1-0.6-0.4-0.9-3.2-0.5-2.72.11.3
Median of all reaction times0.91.59.1-0.70.40.4-0.4-0.3-0.40.40.4-0.6-0.32.6-0.1-0.3-0.1-0.5-3.0-0.3-2.31.81.3
Reaction time omissions0.20.42.50.5-1.2-0.0-0.10.10.1-0.1-0.1-0.00.10.50.2-0.3-0.2-0.2-1.4-0.0-1.60.4-0.5
Reaction time false alarm rate0.81.12.51.00.3-1.31.21.31.6-1.3-1.41.01.4-0.71.1-0.9-1.0-0.51.4-0.80.90.10.6
Reaction time premature initiation rate0.81.22.31.00.0-1.11.31.51.4-1.5-1.51.11.50.01.3-1.2-1.2-1.00.5-1.0-0.30.80.7
Reaction time premature initiations0.30.91.50.8-0.5-0.91.01.11.0-1.1-1.10.91.20.51.1-1.2-1.1-1.0-0.5-1.0-1.00.80.8
Std. dev. reaction times0.41.35.41.0-1.1-1.10.80.81.0-0.8-0.80.70.90.90.9-1.3-1.1-1.4-1.6-1.0-2.31.60.7
Reaction time trials completed0.10.42.7-0.2-0.90.1-0.2-0.5-0.50.40.4-0.2-0.30.9-0.20.00.0-0.2-1.7-0.0-1.30.30.2
Reaction time trials AUC0.10.32.2-0.1-1.0-0.0-0.1-0.4-0.30.30.3-0.0-0.20.8-0.1-0.1-0.1-0.3-1.5-0.2-1.20.30.2
Run reversals in cocaine runway, females0.10.10.4-0.0-0.20.4-0.2-0.2-0.30.20.2-0.2-0.3-0.2-0.20.10.1-0.2-0.10.3-0.60.3-0.6
Run reversals in cocaine runway, males0.20.31.0-0.21.0-0.10.20.20.2-0.2-0.20.20.11.00.4-0.5-0.4-0.3-0.6-0.6-0.50.40.9
Latency to leave start box in cocaine runway1.41.96.9-1.50.41.6-1.3-1.5-1.81.51.6-1.5-1.81.6-1.21.11.00.6-2.61.0-1.1-0.2-0.1
Latency to leave start box in cocaine runway, F0.70.82.5-0.9-0.11.0-0.9-1.0-1.40.91.0-0.8-1.60.7-0.80.80.80.5-1.40.7-0.5-0.7-0.3
Latency to leave start box in cocaine runway, M0.60.64.7-0.50.40.6-0.4-0.5-0.50.50.6-0.6-0.41.3-0.30.00.0-0.2-2.20.1-1.20.80.5
Std. dev. time between licks in bursts1.42.74.4-1.40.81.5-1.6-1.5-1.71.51.5-1.8-1.7-0.8-1.72.01.91.91.21.92.1-2.0-1.2
Total sessions with >9 infusions0.10.10.9-0.31.00.30.20.1-0.0-0.0-0.00.0-0.00.40.0-0.1-0.1-0.4-0.2-0.3-0.30.80.4
Short access day 1 total inactive lever presses0.71.42.6-0.90.21.2-1.0-1.1-1.21.11.1-0.9-1.3-1.1-1.41.41.41.10.91.31.4-1.6-1.4
Short access day 10 total inactive lever presses0.10.71.61.2-1.3-1.01.01.00.9-1.1-1.11.00.8-0.70.8-1.0-0.7-0.50.2-0.7-0.20.1-0.1
Short access day 1 total infusions0.00.10.5-0.20.70.30.30.1-0.1-0.0-0.00.1-0.00.50.1-0.2-0.10.0-0.2-0.3-0.30.40.2
Short access day 10 total infusions0.71.24.5-1.72.11.3-0.9-1.0-1.01.11.1-1.0-1.01.9-0.80.80.60.8-0.90.20.00.30.8
Short access total infusions0.40.52.7-1.11.60.9-0.5-0.7-0.70.70.7-0.6-0.71.1-0.50.50.50.5-0.40.10.20.20.5
Short access day 1 locomotion0.20.41.70.00.10.10.10.0-0.00.00.1-0.10.01.10.2-0.3-0.3-0.4-1.3-0.3-1.31.30.6
Short access day 10 total locomotion0.10.62.6-0.10.6-0.20.50.40.5-0.3-0.30.10.51.60.5-0.8-0.6-0.5-0.9-0.7-1.31.41.2
Short access total locomotion0.60.84.2-0.61.60.20.30.20.1-0.1-0.0-0.10.12.00.3-0.5-0.5-0.5-1.2-0.7-1.11.81.6
One hour access (0.3 mA shock)0.70.91.6-0.8-0.31.3-1.1-1.1-0.91.11.1-1.2-1.0-0.0-1.11.11.20.5-0.51.2-0.3-0.4-1.1
Compulsive drug intake0.20.41.60.5-1.3-0.1-0.2-0.10.10.10.00.0-0.1-1.2-0.30.00.30.31.00.40.3-0.9-1.2
One hour access (shock baseline)0.30.91.7-1.31.11.2-0.9-1.0-1.01.01.1-1.2-1.01.1-0.90.90.80.6-1.30.8-0.10.20.2
Social response proportion1.72.23.41.6-0.2-1.61.81.91.7-1.8-1.81.81.70.31.8-1.8-1.7-1.2-0.0-1.8-0.81.11.0
Social responses1.92.54.82.2-2.0-1.91.71.82.0-1.8-1.81.72.0-1.51.5-1.6-1.4-1.50.9-1.1-0.60.5-0.3
Social time0.71.04.50.4-0.5-0.60.60.70.5-0.5-0.50.50.51.50.8-1.1-1.0-0.7-2.1-1.0-1.61.81.1
Soleus weight4.312.716.83.9-2.8-4.03.73.73.8-3.7-3.73.63.91.63.9-4.1-4.0-3.3-2.5-3.7-3.93.92.5
Bone: stiffness1.01.85.81.8-1.4-1.71.31.21.5-1.2-1.31.41.4-2.31.0-0.9-1.0-0.92.4-0.60.8-0.5-0.5
Tibialis anterior weight0.51.75.71.7-1.6-1.01.31.11.2-1.2-1.31.01.20.31.3-1.4-1.3-1.3-1.3-1.0-2.41.5-0.2
Time to tail flick, vehicle, before self-admin0.20.21.60.3-0.3-0.20.40.30.2-0.3-0.30.40.2-1.20.10.2-0.1-0.21.30.10.8-0.1-0.5
Time to tail flick, vehicle, after self-admin0.10.10.50.5-0.3-0.30.40.30.3-0.4-0.40.40.3-0.70.3-0.3-0.3-0.40.4-0.20.0-0.5-0.4
Time to tail flick, test, before self-admin1.11.34.3-0.21.3-0.60.50.60.7-0.5-0.50.30.72.10.9-0.8-1.0-0.9-2.0-1.0-1.11.82.1
Time to tail flick, test, after self-admin1.51.62.4-1.0-0.01.2-1.2-1.3-1.31.31.3-1.2-1.4-0.7-1.51.41.51.61.01.41.3-1.5-1.4
Delta time to tail flick, vehicle, before/after SA0.20.21.30.6-1.2-0.40.10.10.2-0.2-0.20.20.3-0.30.2-0.4-0.2-0.6-0.6-0.1-1.0-0.3-0.4
Delta time to tail flick, test, before/after SA1.62.04.6-0.6-0.61.0-1.0-1.1-1.21.11.1-0.9-1.2-1.6-1.51.31.61.92.01.42.0-2.1-1.9
Tibia length0.41.12.11.2-0.6-1.21.01.41.1-1.4-1.41.11.3-0.81.2-1.0-1.0-1.10.9-0.8-0.10.40.2
Ambulatory time before self-admin0.30.94.7-0.92.20.2-0.10.10.1-0.1-0.10.10.22.20.4-0.4-0.4-0.2-1.4-0.9-0.41.21.8
Ambulatory time after self-admin0.60.94.9-0.71.50.4-0.20.10.20.00.0-0.10.12.10.3-0.2-0.4-0.3-2.2-0.6-1.11.41.2
Bone: tissue strength0.70.71.3-0.90.21.1-1.0-1.0-1.21.01.0-1.0-1.1-0.1-0.90.90.90.7-0.31.00.4-0.3-0.6
Total heroin consumption1.72.07.72.2-2.8-1.71.31.41.4-1.3-1.31.31.3-1.21.2-1.4-1.2-1.6-0.1-0.7-1.50.8-0.3
Bone: trabecular number0.71.46.91.8-2.1-1.10.61.00.8-0.9-0.90.70.7-2.60.5-0.4-0.3-0.41.90.20.5-0.5-1.6
Bone: trabecular spacing1.92.85.7-2.41.82.2-1.9-2.0-1.61.91.9-1.9-1.71.4-1.71.71.81.7-0.61.40.6-1.2-0.3
Bone: trabecular thickness3.85.313.63.4-3.7-2.82.42.52.4-2.5-2.52.42.5-2.52.2-2.2-2.0-2.21.1-1.3-1.00.9-0.6
Bone: trabecular tissue density0.81.56.5-1.71.61.3-1.0-1.1-1.11.11.1-1.2-0.92.6-0.70.70.61.1-2.00.4-0.1-0.11.0
Water consumed over 24 hours0.10.10.60.20.3-0.50.20.40.4-0.3-0.30.20.20.50.3-0.4-0.4-0.1-0.2-0.4-0.10.50.8
Number of responses in last shaping day0.10.10.5-0.20.40.20.10.1-0.3-0.1-0.0-0.0-0.10.60.1-0.1-0.1-0.3-0.7-0.2-0.50.40.5