Hub : Genes

Stard3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Stard3 0.05 0.03 3.1e-06 0.04 0.06 0.05 0.05 2.1e-04 4.3e-06 3.0e-05 1.2e-05
2 NAcc gene expression Stard3 0.03 0.02 6.5e-04 0.02 0.02 0.01 0.02 2.4e-04 4.1e-04 1.8e-03 4.0e-04
3 IC gene expression Stard3 0.06 0.06 8.8e-03 0.04 0.03 0.04 0.03 7.7e-03 1.6e-02 1.0e-02 2.6e-02
4 Liver alternative TSS NM_001014229.1 0.03 0.02 4.9e-04 0.04 0.02 0.02 0.03 6.4e-05 9.8e-04 1.5e-03 5.5e-04
5 Adipose gene expression Stard3 0.02 0.02 1.5e-03 0.02 0.02 0.02 0.02 1.6e-03 2.5e-03 6.2e-03 5.1e-03
6 Adipose alternative polyA NM_001014229.1 0.04 0.03 3.6e-03 0 0.01 0.01 0 9.4e-02 8.8e-03 3.5e-02 8.0e-02
7 Adipose alternative polyA XM_039086506.2 0.04 0.04 3.5e-03 0 0.01 0.01 0 1.8e-01 8.9e-03 3.6e-02 7.4e-02
8 PL gene expression Stard3 0.09 0.06 1.8e-05 0.01 0.04 0.04 0.04 9.7e-03 6.5e-05 4.6e-05 1.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density2.03.74.42.0-2.1-2.12.1-2.0-2.02.01.1
Area under the delay curve0.40.71.50.9-1.2-0.60.6-0.8-1.01.00.3
BMI with tail1.96.89.9-3.22.83.1-3.12.92.2-2.10.5
BMI without tail0.84.06.1-2.42.22.1-2.12.51.8-1.80.4
Body weight6.327.739.0-6.25.75.6-5.66.05.1-5.0-0.4
Weight adjusted by age0.10.20.3-0.50.30.6-0.60.50.2-0.20.5
Bone surface0.10.10.6-0.0-0.5-0.20.2-0.1-0.30.30.8
Bone volume0.30.62.10.3-0.8-0.60.6-0.5-0.80.91.5
Breakpoint value in progressive ratio session0.71.22.5-1.11.60.5-0.51.51.3-1.3-0.1
Number of licking bursts0.30.82.70.5-0.5-0.10.1-0.9-1.11.11.7
Context. condit. distance diff. score1.01.32.2-0.80.91.4-1.40.71.1-1.1-1.5
Locomotion velocity, session 10.50.50.9-1.00.80.5-0.50.90.8-0.80.2
Locomotion distance, session 12.53.25.6-2.32.01.4-1.42.41.8-1.80.0
Locomotion velocity, session 20.40.50.8-0.70.80.3-0.30.80.9-0.9-0.4
Locomotion distance, session 20.40.61.6-1.00.80.2-0.21.30.7-0.70.6
Locomotion velocity, session 30.20.20.6-0.20.3-0.10.10.40.5-0.5-0.8
Locomotion distance, session 30.30.40.6-0.70.60.5-0.50.80.7-0.6-0.3
Stereotopy head waving bouts, day 32.73.34.72.1-2.0-1.71.7-2.2-1.91.80.7
Stereotopy head waving duration, day 30.40.50.90.7-0.7-0.40.4-1.0-0.80.80.6
Locomotion velocity, session 70.70.81.4-1.20.91.0-1.01.00.8-0.80.2
Locomotion distance, session 70.20.20.4-0.60.50.6-0.60.30.4-0.4-0.1
Stereotopy head waving bouts, day 71.01.21.91.2-1.3-0.70.7-1.4-1.31.30.4
Stereotopy head waving duration, day 70.30.30.60.6-0.7-0.40.4-0.8-0.70.70.1
Locomotion velocity, session 86.78.19.6-3.13.03.0-3.03.02.9-2.9-1.6
Locomotion distance, session 81.31.92.8-1.61.51.4-1.41.71.4-1.4-0.4
Degree of sensitization distance0.40.50.8-0.70.80.9-0.90.40.6-0.6-0.5
Degree of sensitization stereotypy1.31.42.41.2-1.5-0.70.7-1.5-1.41.50.5
Conditioned locomotion0.20.20.70.5-0.4-0.50.5-0.4-0.10.1-0.8
Cocaine response after cond. corrected1.62.44.11.2-1.8-0.60.6-1.8-2.02.01.7
Cocaine response after cond. not corrected2.33.35.61.3-2.0-0.60.6-2.2-2.32.42.0
Cocaine response before conditioning0.20.30.80.5-0.5-0.10.1-0.9-0.60.60.3
Saline control response0.20.30.8-0.5-0.00.9-0.9-0.1-0.20.20.6
Bone: connectivity density2.74.45.32.3-2.3-2.32.3-2.1-2.12.10.8
Bone: cortical apparent density3.96.29.83.1-2.7-2.72.7-2.7-2.22.2-0.4
Bone: cortical area0.10.20.50.5-0.7-0.30.3-0.6-0.50.50.2
Bone: cortical porosity0.80.91.50.7-1.0-0.40.4-1.0-1.11.21.2
Bone: cortical porosity0.70.71.40.5-0.8-0.30.3-1.0-1.11.11.2
Bone: cortical thickness1.11.82.91.6-1.5-1.11.1-1.7-1.41.4-0.1
Bone: cortical thickness4.04.96.62.6-2.2-2.52.5-2.4-2.12.10.4
Bone: cortical tissue density3.96.29.83.1-2.7-2.72.7-2.7-2.22.2-0.4
Condit. Reinf. active minus inactive responses0.50.61.01.0-0.8-1.01.0-0.7-0.50.5-0.3
Condit. Reinf. active-inactive response ratio0.70.81.41.2-0.9-1.01.0-0.8-0.50.5-0.9
Condit. Reinf. active responses0.70.91.31.1-0.9-1.21.2-1.0-0.80.70.0
Condit. Reinf. inactive responses0.40.50.90.5-0.6-0.60.6-0.9-0.80.80.9
Incentive salience index mean1.31.72.61.5-1.3-1.61.6-1.3-1.11.10.1
Condit. Reinf. lever presses1.21.72.31.4-1.4-1.51.5-1.3-1.31.30.6
Condit. Reinf. active minus inactive responses0.61.01.61.0-0.7-1.31.3-0.8-0.90.90.8
Condit. Reinf. active-inactive response ratio0.60.91.40.8-0.6-1.21.2-0.6-0.90.91.2
Condit. Reinf. active responses1.21.72.61.2-1.0-1.61.6-1.0-1.31.31.3
Condit. Reinf. inactive responses1.31.92.11.3-1.3-1.51.5-1.4-1.51.51.1
Condit. Reinf. lever presses0.00.00.10.2-0.2-0.20.2-0.1-0.20.20.2
Condit. Reinf. lever reinforcers received1.21.62.91.2-1.0-1.71.7-1.0-1.21.21.0
Conditioned reinforcement - actives0.10.30.90.5-0.9-0.00.0-0.8-0.50.5-0.0
Conditioned reinforcement - inactives0.00.10.30.3-0.1-0.50.50.00.0-0.0-0.2
Conditioned locomotion0.71.11.51.1-1.2-0.70.7-1.1-1.21.20.9
Patch foraging indifference point 0 sec0.82.24.11.8-2.0-1.71.7-1.3-1.21.2-0.3
Patch foraging indifference point AUC0.00.00.2-0.0-0.4-0.00.0-0.1-0.10.1-0.2
Delay disc. indifference point, 0s delay1.82.02.51.6-1.5-1.41.4-1.5-1.51.50.8
Delay disc. indifference point, 16s delay0.40.51.00.9-0.9-0.50.5-0.7-0.50.5-1.0
Delay disc. indifference point, 2s delay2.32.53.51.3-1.8-1.11.1-1.5-1.81.91.8
Delay disc. indifference point, 24s delay0.10.10.30.0-0.30.6-0.6-0.2-0.00.0-0.5
Delay disc. indifference point, 4s delay1.01.01.61.0-1.2-1.11.1-0.6-1.11.10.8
Delay disc. indifference point, 8s delay0.10.20.70.5-0.9-0.20.2-0.3-0.60.60.1
Indifference point function ln k0.00.10.60.1-0.00.3-0.30.10.2-0.2-0.7
Indifference point function log k0.00.10.60.1-0.00.3-0.30.10.2-0.2-0.7
Patch foraging total patch changes 0 sec0.51.53.11.4-1.8-1.41.4-1.0-0.90.9-0.5
Patch foraging total patch changes 12 sec4.35.76.82.5-2.6-2.62.6-2.4-2.42.41.4
Patch foraging total patch changes 18 sec0.20.41.00.6-1.0-0.80.8-0.7-0.50.5-0.2
Patch foraging total patch changes 24 sec0.51.62.81.4-1.4-1.11.1-1.7-1.41.4-0.1
Patch foraging total patch changes 6 sec1.32.23.81.6-1.8-1.91.9-1.2-1.31.30.2
Patch foraging time to switch 0 sec0.00.10.20.2-0.1-0.40.4-0.1-0.10.10.2
Patch foraging water rate 0 sec0.00.00.10.2-0.0-0.30.30.1-0.10.10.0
Patch foraging water rate 12 sec0.10.50.9-0.41.00.6-0.60.60.7-0.8-0.8
Patch foraging water rate 18 sec0.20.50.80.7-0.4-0.50.5-0.7-0.80.80.9
Patch foraging water rate 24 sec0.30.51.20.7-0.3-1.11.1-0.3-0.50.50.4
Patch foraging water rate 6 sec0.91.32.01.3-0.8-1.41.4-1.1-1.11.10.4
Seeking ratio, delayed vs. immediate footshock0.30.42.4-0.10.5-0.20.20.10.6-0.6-1.6
Distance traveled before self-admin0.10.20.4-0.30.5-0.40.40.60.3-0.40.4
Distance traveled after self-admin0.40.81.2-1.11.00.5-0.51.01.0-1.00.3
Extensor digitorum longus weight8.333.140.1-6.26.16.3-6.35.85.8-5.7-3.1
Bone: elastic displacement0.00.00.10.1-0.20.1-0.1-0.2-0.20.20.3
Bone: elastic work0.20.21.20.1-0.4-0.20.2-0.1-0.30.31.1
Bone: endosteal estimation1.53.65.8-2.41.62.1-2.12.11.8-1.70.5
Bone: endosteal perimeter1.12.84.5-2.11.61.6-1.62.11.8-1.70.2
Epididymis fat weight0.10.51.6-0.80.60.8-0.80.40.2-0.21.3
Delta time in closed arm before/after self-admin3.83.65.9-2.22.41.9-1.92.11.8-1.7-0.7
Delta time in open arm before/after self-admin0.00.00.10.10.20.3-0.30.0-0.10.10.2
Diff in mean of infusions in LGA sessions0.10.20.6-0.40.80.2-0.20.60.5-0.50.1
Delay discount exponential model param0.30.41.0-0.71.00.4-0.40.50.7-0.7-0.2
Extinction: sum of active levers before priming0.81.32.9-1.20.81.7-1.70.90.8-0.8-0.0
Active lever presses in extinction session 61.01.06.70.1-0.6-0.30.3-0.0-0.60.72.6
Bone: final force1.11.82.81.0-1.5-0.80.8-1.5-1.51.61.7
Bone: final moment0.91.52.70.9-1.3-0.60.6-1.3-1.41.41.6
Food consumed during 24 hour testing period0.40.81.1-1.11.00.9-0.90.90.8-0.80.3
Glucose0.61.02.60.4-1.0-0.10.1-1.0-1.31.31.6
Heart weight2.74.36.2-2.42.12.2-2.22.52.1-2.0-0.2
Delay discount hyperbolic model param0.30.40.9-0.61.00.4-0.40.50.7-0.7-0.4
Intermittent access intake day 1-15 change0.00.20.6-0.30.7-0.10.10.60.5-0.5-0.2
Intermittent access intake escalation0.00.20.5-0.30.7-0.00.00.60.5-0.5-0.1
Intermittent access intake escalation 20.30.51.3-0.81.10.6-0.60.80.8-0.7-0.1
Intermitt. access day 1 inactive lever presses0.11.02.81.0-0.3-1.71.7-0.5-0.70.70.3
Intermitt. access day 15 inactive lever presses0.21.22.21.4-0.6-1.51.5-1.0-1.00.9-0.5
Intermitt. access escalation Index0.51.42.5-1.40.91.6-1.61.11.1-1.0-0.5
Intermittent access day 1 total infusions0.00.00.10.1-0.2-0.40.40.20.1-0.10.1
Intermittent access day 15 total infusions0.10.20.4-0.30.6-0.10.10.70.5-0.5-0.3
Intermittent access terminal intake (last 3 days)0.00.10.20.10.1-0.40.40.10.2-0.2-0.2
Intermittent access total infusions0.10.10.2-0.20.4-0.20.20.40.5-0.5-0.3
Intermittent access day 1 locomotion0.10.10.20.3-0.5-0.40.4-0.1-0.20.20.2
Intermittent access day 15 total locomotion0.20.61.30.7-0.8-0.60.6-0.6-0.80.81.1
Intermittent access total locomotion0.80.91.31.1-1.1-1.01.0-0.9-1.01.00.5
Intermittent access standard deviation0.10.62.20.80.1-1.51.5-0.2-0.20.2-0.3
Left kidney weight0.53.95.7-2.02.41.3-1.32.42.3-2.3-1.5
Right kidney weight0.00.20.5-0.60.70.0-0.00.70.5-0.40.3
Cocaine induced anxiety1.64.25.6-2.42.22.1-2.12.42.1-2.1-0.6
Post-drug Anxiety1.11.31.4-1.21.11.1-1.11.21.2-1.2-0.9
Baseline Anxiety1.82.94.71.9-2.2-1.41.4-2.0-1.91.80.6
Tail length0.84.36.9-2.02.11.6-1.62.62.4-2.4-1.6
Length with tail3.415.123.1-4.34.33.4-3.44.84.2-4.2-1.6
Length without tail1.78.912.3-3.53.23.1-3.13.52.9-2.9-0.5
Times rat made contact with spout1.21.41.81.1-0.9-1.21.2-1.2-1.31.31.3
Lifetime Intake0.10.10.20.00.2-0.40.40.40.3-0.3-0.3
Liver weight, left0.20.30.7-0.70.50.8-0.80.50.3-0.30.3
Liver weight, right0.30.50.80.8-0.8-0.90.9-0.8-0.60.5-0.5
Locomotor activity0.71.02.40.8-0.9-0.50.5-1.0-1.21.21.5
Locomotor testing distance1.43.34.32.0-2.0-1.61.6-2.1-2.02.01.1
Locomotor testing rearing2.07.410.13.2-3.2-3.23.2-2.7-2.52.40.4
Locomotion in novel chamber4.76.47.92.7-2.8-2.72.7-2.3-2.62.61.7
Locomotion in novel chamber post-restriction0.31.04.20.4-0.6-0.80.8-0.5-0.91.02.0
Fecal boli incidents, locomotor time 10.00.10.4-0.40.40.1-0.10.60.2-0.20.3
Change in fecal boli incidents, locomotor task0.20.30.50.4-0.70.2-0.2-0.7-0.60.60.4
Time >=10cm from walls, locomotor time 10.40.51.00.8-1.0-0.20.2-1.0-0.50.5-0.8
Bouts of movement, locomotor time 10.50.60.9-0.91.00.8-0.80.60.9-0.8-0.5
Total resting periods, locomotor time 10.80.91.4-1.21.11.1-1.10.80.9-0.9-0.2
Rest time, locomotor task time 10.00.00.2-0.10.2-0.20.20.10.0-0.00.4
Distance moved, locomotor task time 10.00.10.10.2-0.3-0.30.3-0.3-0.30.3-0.1
Vertical activity count, locomotor time 10.00.20.4-0.50.10.6-0.60.50.2-0.20.0
Time >=10cm from walls, locomotor time 20.51.42.91.3-1.7-0.80.8-1.3-1.31.30.3
Bouts of movement, locomotor time 20.10.31.80.5-0.2-0.50.5-0.20.1-0.2-1.3
Total resting periods, locomotor time 20.10.42.50.20.1-0.30.30.10.4-0.5-1.6
Rest time, locomotor task time 20.71.11.8-1.11.11.0-1.01.31.1-1.1-0.5
Distance moved, locomotor task time 20.00.00.1-0.2-0.30.1-0.10.1-0.20.20.4
Vertical activity count, locomotor time 20.10.20.4-0.50.10.7-0.70.40.2-0.10.0
Light reinforcement 10.73.04.31.9-2.0-2.12.1-1.5-1.61.60.6
Light reinforcement 20.51.23.20.7-0.9-0.70.7-0.9-1.21.21.8
Bone: marrow area1.43.45.4-2.31.62.1-2.12.11.8-1.70.5
Bone: maximum diameter0.00.00.10.0-0.2-0.20.2-0.0-0.10.10.3
Bone: maximum force0.10.10.7-0.2-0.20.3-0.3-0.2-0.20.20.8
Bone: maximum moment0.10.20.6-0.3-0.10.5-0.5-0.1-0.10.10.8
Mean time between licks in bursts0.31.82.7-1.61.31.4-1.41.61.4-1.4-0.2
Mean num. licks in bursts0.10.20.40.3-0.2-0.70.70.00.0-0.0-0.5
Cd content in liver1.31.41.8-1.31.21.3-1.31.21.2-1.2-0.3
Co content in liver2.22.63.4-1.51.71.4-1.41.61.8-1.8-1.6
Cu content in liver0.50.51.8-0.30.2-0.30.30.80.9-0.9-1.3
Fe content in liver1.31.62.8-1.71.31.1-1.11.61.2-1.20.2
K content in liver0.50.50.90.7-0.9-1.01.0-0.2-0.20.2-0.6
Mg content in liver0.60.72.80.9-0.7-0.80.8-0.4-0.0-0.0-1.7
Mn content in liver0.70.81.80.9-1.1-1.11.1-0.2-0.0-0.0-1.3
Na content in liver0.60.72.50.3-0.5-0.60.6-0.5-0.80.91.6
Rb content in liver1.51.83.61.5-1.9-1.51.5-1.2-1.21.20.0
Se content in liver4.55.38.42.8-2.6-2.92.9-2.1-1.91.80.0
Sr content in liver1.21.12.8-0.50.80.5-0.51.01.3-1.3-1.7
Zn content in liver2.12.44.41.8-1.5-2.12.1-1.3-1.31.20.1
Bone: minimum diameter0.40.71.3-1.10.31.0-1.01.00.8-0.80.1
Time in familiar zone, hab. session 10.90.94.30.3-0.5-0.40.4-0.5-1.11.12.1
Time in novel zone, hab. session 10.50.61.41.0-0.8-0.50.5-1.0-0.40.4-1.2
Total zone transitions, hab. session 11.92.63.2-1.71.81.5-1.51.81.7-1.7-1.0
Total locomotion distance, hab. session 10.00.00.1-0.10.30.1-0.10.20.2-0.2-0.2
Locomotion velocity, hab. session 10.50.71.1-0.81.10.7-0.71.00.9-0.9-0.5
Time in familiar zone, hab. session 20.50.50.80.6-0.7-0.50.5-0.7-0.90.90.9
Time in novel zone, hab. session 20.10.10.20.4-0.2-0.40.4-0.2-0.00.0-0.3
Total zone transitions, hab. session 20.70.91.5-1.10.71.2-1.21.00.8-0.8-0.4
Total locomotion distance, hab. session 20.20.30.5-0.60.40.6-0.60.50.2-0.20.7
Locomotion velocity, hab. session 20.40.50.8-0.90.70.9-0.90.70.5-0.40.4
Novel to familiar place preference ratio1.31.72.4-1.11.41.1-1.11.31.5-1.5-1.5
Novelty place preference1.11.52.7-0.91.21.0-1.01.01.4-1.4-1.6
Time in novel zone, NPP test0.50.71.8-0.40.70.8-0.80.50.8-0.9-1.3
Total zone transitions, NPP test0.30.40.8-0.90.40.6-0.60.70.3-0.30.8
Total locomotion distance, NPP test0.10.21.1-0.2-0.2-0.00.0-0.0-0.40.41.1
Locomotion velocity, NPP test0.20.20.5-0.70.50.2-0.20.60.4-0.30.6
Intraocular pressure1.52.43.4-1.81.61.5-1.51.71.6-1.6-0.7
Delta distance traveled before/after self-admin1.01.11.9-1.10.81.4-1.40.81.0-1.0-0.6
Delta ambulatory time before/after self-admin0.50.92.2-1.00.71.5-1.50.60.6-0.6-0.0
Parametrial fat weight0.41.02.30.7-0.7-0.90.9-0.8-1.11.11.5
Pavlov. Cond. lever latency2.83.54.4-1.71.91.9-1.91.82.1-2.1-1.6
Pavlov. Cond. magazine entry latency10.012.814.93.7-3.6-3.93.9-3.6-3.73.72.4
Pavlov. Cond. change in total contacts8.59.212.23.5-3.2-3.43.4-3.2-3.02.90.7
Pavlov. Cond. index score9.311.713.23.4-3.5-3.63.6-3.4-3.63.62.5
Pavlov. Cond. latency score7.39.310.83.0-3.1-3.13.1-3.0-3.33.32.3
Pavlov. Cond. lever contacts3.54.35.11.9-2.0-2.12.1-2.0-2.22.31.8
Pavlov. Cond. magazine entry number13.417.019.5-4.44.34.3-4.34.34.3-4.3-2.4
Pavlov. Cond. intertrial magazine entries1.51.92.3-1.31.21.5-1.51.31.5-1.5-1.2
Pavlov. Cond. lever-magazine prob. diff.10.813.415.03.7-3.7-3.93.9-3.7-3.83.82.6
Pavlov. Cond. response bias10.412.914.83.8-3.7-3.93.9-3.7-3.73.72.1
Pavlov. Cond. lever latency0.50.81.5-0.70.61.0-1.00.60.8-0.8-1.2
Pavlov. Cond. magazine entry latency0.00.10.3-0.20.20.2-0.20.1-0.10.10.6
Pavlov. Cond. change in total contacts0.30.81.40.9-0.8-1.21.2-0.7-0.70.70.5
Pavlov. Cond. index score0.30.41.30.4-0.4-0.60.6-0.5-0.70.71.1
Pavlov. Cond. latency score0.20.31.00.3-0.4-0.40.4-0.4-0.60.61.0
Pavlov. Cond. lever contacts0.71.12.40.7-0.8-1.01.0-0.8-1.11.11.5
Pavlov. Cond. magazine entry number0.20.30.5-0.30.40.4-0.40.50.6-0.6-0.7
Pavlov. Cond. intertrial magazine entries1.43.15.4-1.41.71.6-1.61.51.9-2.0-2.3
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.2-0.3-0.50.5-0.3-0.50.51.0
Pavlov. Cond. response bias1.21.72.71.0-1.0-1.41.4-1.1-1.31.31.6
Time in closed arm before self-admin1.22.13.01.6-1.7-1.71.7-1.6-1.11.0-0.5
Time in closed arm after self-admin0.60.62.5-0.30.5-0.10.10.70.9-0.9-1.6
Time in open arm before self-admin1.72.13.0-1.61.31.6-1.61.71.4-1.4-0.5
Time in open arm after self-admin0.40.40.9-0.60.60.9-0.90.60.5-0.40.1
Bone: periosteal estimation0.20.40.7-0.80.20.7-0.70.60.4-0.40.6
Bone: periosteal perimeter0.50.91.8-1.30.90.9-0.91.10.7-0.70.9
Bone: post-yield work0.71.31.7-1.31.31.2-1.21.11.1-1.1-0.4
Progressive ratio test 1 active lever presses0.10.20.60.4-0.8-0.20.2-0.6-0.40.40.1
Progressive ratio test 1 breakpoint0.10.10.40.3-0.6-0.10.1-0.6-0.30.30.0
Progressive ratio test 1 inactive lever presses0.00.10.40.20.1-0.50.50.10.1-0.1-0.7
Progressive ratio test 2 active lever presses0.50.61.20.9-0.8-1.11.1-0.7-0.70.60.2
Progressive ratio test 2 breakpoint0.60.71.30.9-0.8-1.21.2-0.7-0.70.70.3
Progressive ratio test 2 inactive lever presses0.00.10.40.10.2-0.60.60.50.2-0.2-0.2
Incentive Sensitization - Responses0.51.32.51.2-0.9-1.61.6-0.8-1.01.00.7
Incentive Sensitization - Breakpoint0.51.22.31.2-0.9-1.51.5-0.7-0.90.90.8
Sum of active levers in priming session hrs 5-60.20.20.70.3-0.5-0.10.1-0.3-0.40.40.8
Progressive ratio0.00.00.1-0.0-0.3-0.20.20.00.0-0.0-0.1
Food seeking constrained by brief footshock0.40.51.00.6-0.8-0.60.6-1.0-0.70.70.8
Seeking ratio, punishment vs. effort0.00.10.30.3-0.20.0-0.0-0.6-0.40.40.2
Retroperitoneal fat weight0.10.30.40.5-0.6-0.60.6-0.6-0.50.50.2
Reaction time number correct0.31.01.6-1.21.20.9-0.91.30.8-0.80.6
Reaction time mean minus median0.00.30.6-0.50.60.7-0.70.20.4-0.4-0.5
Reaction time mean minus median AUC0.00.10.50.2-0.20.2-0.2-0.7-0.50.5-0.1
Reaction time num false alarms0.71.32.70.8-1.0-1.11.1-0.9-1.11.11.6
Reaction time num false alarms AUC0.41.02.50.6-0.8-0.90.9-0.8-1.01.01.6
Reaction time trials correct on left0.31.01.6-1.21.20.9-0.91.30.8-0.80.6
Reaction time trials on left0.30.91.5-1.11.20.9-0.91.20.8-0.70.7
Reaction time mean0.10.20.90.50.1-0.40.4-0.20.0-0.0-1.0
Reaction time mean AUC0.10.21.10.40.1-0.40.4-0.10.1-0.1-1.0
Median of all reaction times0.40.61.11.0-0.4-1.11.1-0.6-0.40.4-0.7
Reaction time omissions0.20.40.60.7-0.5-0.80.8-0.7-0.60.60.2
Reaction time false alarm rate1.21.62.01.2-1.3-1.31.3-1.4-1.31.31.1
Reaction time premature initiation rate0.20.41.20.5-0.4-0.30.3-0.7-0.50.51.1
Reaction time premature initiations0.10.31.4-0.40.50.5-0.50.30.2-0.21.2
Std. dev. reaction times0.00.00.10.10.20.1-0.1-0.2-0.10.1-0.4
Reaction time trials completed0.30.91.5-1.11.20.9-0.91.20.8-0.70.7
Reaction time trials AUC0.20.81.3-1.11.10.9-0.91.10.7-0.70.5
Run reversals in cocaine runway, females1.71.92.1-1.21.41.4-1.41.21.4-1.4-1.4
Run reversals in cocaine runway, males0.30.30.40.6-0.5-0.40.4-0.6-0.70.70.6
Latency to leave start box in cocaine runway1.21.62.6-1.51.50.7-0.71.61.6-1.6-0.7
Latency to leave start box in cocaine runway, F1.82.23.4-1.81.71.2-1.21.81.7-1.7-0.4
Latency to leave start box in cocaine runway, M0.30.30.60.10.0-0.80.80.20.3-0.4-0.7
Std. dev. time between licks in bursts0.10.10.2-0.50.30.2-0.20.50.3-0.30.4
Total sessions with >9 infusions0.20.21.30.2-0.1-0.30.30.10.2-0.2-1.1
Short access day 1 total inactive lever presses0.71.43.11.3-0.9-1.81.8-0.8-1.01.00.4
Short access day 10 total inactive lever presses0.10.51.4-0.51.20.2-0.20.80.7-0.7-0.4
Short access day 1 total infusions0.20.30.70.5-0.3-0.80.8-0.2-0.00.0-0.9
Short access day 10 total infusions0.20.30.80.6-0.6-0.90.9-0.4-0.40.40.3
Short access total infusions0.10.10.50.3-0.1-0.70.70.10.1-0.1-0.3
Short access day 1 locomotion0.50.91.61.1-0.9-1.31.3-0.8-0.80.7-0.2
Short access day 10 total locomotion0.73.04.11.8-2.0-1.81.8-1.7-1.81.71.1
Short access total locomotion0.20.30.70.6-0.8-0.80.8-0.3-0.40.40.1
One hour access (0.3 mA shock)0.20.20.5-0.40.10.6-0.60.20.4-0.4-0.7
Compulsive drug intake0.60.85.50.1-0.40.5-0.5-0.70.2-0.2-2.3
One hour access (shock baseline)0.10.20.6-0.30.50.0-0.00.70.4-0.40.3
Social response proportion0.10.10.3-0.30.10.6-0.6-0.10.0-0.0-0.1
Social responses0.20.31.30.1-0.7-0.20.2-0.2-0.60.61.1
Social time0.30.42.6-0.3-0.10.3-0.30.1-0.40.41.6
Soleus weight0.41.33.70.4-0.50.5-0.5-1.3-1.41.51.9
Bone: stiffness0.00.10.3-0.1-0.10.0-0.0-0.2-0.20.20.6
Tibialis anterior weight1.24.25.9-2.42.42.3-2.32.11.8-1.70.0
Time to tail flick, vehicle, before self-admin0.30.41.80.3-0.5-0.10.1-0.4-0.60.71.4
Time to tail flick, vehicle, after self-admin0.00.10.20.1-0.5-0.00.0-0.4-0.30.30.3
Time to tail flick, test, before self-admin0.81.02.4-1.00.71.6-1.60.60.7-0.7-0.2
Time to tail flick, test, after self-admin0.60.73.60.2-0.2-0.60.6-0.3-0.70.71.9
Delta time to tail flick, vehicle, before/after SA0.40.50.60.5-0.6-0.50.5-0.8-0.80.80.8
Delta time to tail flick, test, before/after SA2.43.04.41.7-1.4-2.12.1-1.4-1.71.71.6
Tibia length0.82.34.0-2.01.62.0-2.01.30.9-0.91.0
Ambulatory time before self-admin0.10.30.9-0.50.7-0.10.11.00.7-0.70.0
Ambulatory time after self-admin1.32.13.2-1.81.71.3-1.31.61.5-1.50.4
Bone: tissue strength0.91.02.0-0.91.21.4-1.40.40.7-0.7-0.4
Total heroin consumption2.12.57.61.2-1.2-1.71.7-0.7-1.31.32.8
Bone: trabecular number4.68.710.63.0-3.3-3.03.0-3.0-3.13.11.8
Bone: trabecular spacing1.11.62.6-1.61.51.5-1.51.20.9-0.90.8
Bone: trabecular thickness0.10.10.20.3-0.1-0.40.4-0.3-0.30.30.1
Bone: trabecular tissue density0.50.95.60.10.20.6-0.6-0.00.7-0.7-2.4
Water consumed over 24 hours0.10.10.6-0.30.40.3-0.3-0.0-0.10.10.8
Number of responses in last shaping day0.30.42.30.30.3-0.40.40.20.2-0.3-1.5