Hub : Genes

Cacnb3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Cacnb3 0.11 0.06 0.0e+00 0.15 0.15 0.16 0.16 1.5e-16 1.2e-16 4.9e-17 7.3e-17
2 PL mRNA stability Cacnb3 0.02 0.02 3.8e-03 0.02 0.01 0.01 0.01 5.4e-03 8.2e-03 3.5e-02 9.3e-03
3 Brain gene expression Cacnb3 0.23 0.1 0.0e+00 0.36 0.34 0.36 0.35 4.8e-35 9.2e-33 5.8e-35 1.1e-33
4 IL gene expression Cacnb3 0.2 0.13 3.1e-04 0.15 0.15 0.15 0.15 1.6e-04 2.2e-04 1.5e-04 2.0e-04
5 Eye gene expression Cacnb3 0.22 0.14 1.8e-03 0.24 0.21 0.24 0.22 1.1e-04 3.9e-04 1.2e-04 2.9e-04
6 BLA gene expression Cacnb3 0.11 0.07 8.6e-07 0.12 0.13 0.11 0.12 8.6e-07 3.1e-07 1.1e-06 7.9e-07
7 Brain alternative TSS NM_012828.3 0.15 0.22 2.4e-03 0.02 0.01 0.01 0.02 2.3e-03 1.7e-02 6.8e-02 8.2e-03
8 Brain alternative TSS XM_006257329.4 0.09 0.18 2.4e-03 0.03 0.02 0.01 0.02 1.2e-03 4.6e-03 5.4e-02 4.5e-03
9 Brain alternative TSS NM_012828.3 0.09 0.17 2.5e-03 0.02 0.02 0.01 0.02 2.3e-03 1.1e-02 1.4e-02 6.4e-03
10 Brain alternative TSS XM_006257329.4 0.06 0.1 3.0e-03 0.03 0.02 0.01 0.02 1.5e-03 5.6e-03 5.8e-02 4.9e-03
11 Brain isoform ratio XM_006257329.4 0.15 0.27 4.0e-03 0.03 0.01 0.01 0.02 1.9e-03 1.4e-02 7.8e-02 7.2e-03
12 Brain isoform ratio NM_012828.3 0.18 0.21 6.5e-03 0.01 0.01 0 0.01 1.3e-02 8.3e-02 1.4e-01 7.3e-02
13 PL alternative TSS NM_012828.3 0.02 0.02 6.8e-03 0.02 0.02 0.01 0.02 2.9e-03 4.3e-03 7.5e-03 3.7e-03
14 PL alternative TSS XM_006257329.4 0.02 0.02 8.8e-03 0.02 0.02 0.01 0.02 4.8e-03 5.1e-03 1.1e-02 5.7e-03
15 PL isoform ratio NM_012828.3 0.02 0.02 8.8e-03 0.01 0.01 0.01 0.01 1.1e-02 1.6e-02 1.5e-02 1.7e-02
16 OFC alternative TSS XM_006257329.4 0.29 0.2 1.2e-04 0.16 0.18 0.19 0.19 1.6e-04 3.6e-05 2.5e-05 3.4e-05
17 OFC gene expression Cacnb3 0.29 0.14 7.5e-07 0.2 0.2 0.18 0.2 1.6e-05 1.4e-05 5.6e-05 1.6e-05
18 OFC alternative TSS NM_012828.3 0.31 0.24 5.2e-04 0.12 0.15 0.16 0.15 7.1e-04 2.0e-04 1.0e-04 1.9e-04
19 OFC alternative TSS XM_006257329.4 0.33 0.22 1.1e-04 0.16 0.19 0.19 0.19 1.4e-04 2.4e-05 2.6e-05 3.1e-05
20 OFC alternative TSS NM_012828.3 0.34 0.24 2.5e-04 0.13 0.17 0.17 0.16 4.9e-04 9.4e-05 9.7e-05 9.8e-05
21 Brain intron excision ratio chr7_129785003_129791917 0.05 0.04 7.9e-03 0 0.01 0 0.01 1.3e-01 5.8e-02 1.3e-01 4.5e-02
22 PL intron excision ratio chr7_129785003_129791917 0.03 0.04 5.8e-03 0.02 0.01 0.01 0.02 1.7e-03 2.1e-02 3.2e-02 3.8e-03
23 PL intron excision ratio chr7_129787673_129791917 0.05 0.07 2.2e-03 0.02 0.02 0.01 0.02 1.8e-03 5.6e-03 7.8e-03 3.4e-03
24 Liver gene expression Cacnb3 0.03 0.03 3.5e-03 0 0.01 0.02 0.01 1.1e-01 3.9e-02 3.9e-03 3.5e-02
25 LHb isoform ratio NM_012828.3 0.7 0.16 4.5e-03 -0 0.05 -0 -0 4.3e-01 3.1e-02 4.0e-01 3.7e-01
26 LHb isoform ratio XM_006257329.4 0.71 0.16 2.6e-03 0 0.09 0.01 0.03 2.7e-01 3.9e-03 1.5e-01 6.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density8.814.820.2-4.2-4.3-4.2-4.1-4.14.04.1-4.14.1-4.1-4.14.14.1-4.14.1-4.03.73.83.4-3.34.5-3.13.13.8-2.12.0
Area under the delay curve1.11.12.1-1.0-0.9-0.9-1.0-1.11.01.1-1.11.1-1.1-1.11.21.2-1.21.3-0.90.80.90.5-0.41.4-0.80.81.3-1.31.3
BMI with tail4.012.817.1-3.9-3.6-3.8-3.9-4.13.84.0-4.04.0-4.0-4.04.03.9-3.94.0-3.33.53.12.8-2.63.9-3.13.13.2-2.42.2
BMI without tail0.10.10.6-0.10.2-0.0-0.3-0.70.10.2-0.20.2-0.2-0.20.60.4-0.40.40.20.1-0.2-0.50.50.3-0.20.2-0.5-0.80.8
Body weight5.824.335.1-5.4-4.9-5.0-5.3-5.95.25.4-5.45.4-5.4-5.45.55.4-5.45.4-4.85.04.74.3-4.15.0-4.74.74.2-1.81.6
Weight adjusted by age2.32.53.8-1.6-1.6-1.6-1.8-1.81.71.7-1.71.7-1.7-1.71.61.7-1.71.6-1.61.91.61.7-1.70.7-2.02.00.50.8-0.9
Bone surface10.318.223.3-4.6-4.8-4.7-4.6-4.54.54.6-4.64.6-4.6-4.64.54.5-4.54.5-4.44.24.34.0-3.94.5-3.73.73.9-1.71.6
Bone volume7.713.116.5-3.9-4.1-4.1-4.0-3.83.83.9-3.93.9-3.9-3.93.83.8-3.83.8-3.83.53.63.4-3.23.9-3.13.13.4-1.61.5
Breakpoint value in progressive ratio session0.20.20.4-0.6-0.5-0.4-0.4-0.40.50.5-0.50.5-0.5-0.50.40.4-0.40.4-0.30.40.30.5-0.50.3-0.30.30.60.0-0.0
Number of licking bursts0.40.52.80.60.70.50.30.1-0.3-0.30.3-0.30.30.3-0.4-0.40.4-0.40.5-0.0-0.5-0.10.1-1.3-0.30.3-1.71.5-1.5
Context. condit. distance diff. score0.30.30.7-0.7-0.2-0.4-0.6-0.80.60.7-0.70.7-0.7-0.70.60.6-0.60.6-0.50.60.50.5-0.50.6-0.70.70.20.2-0.2
Locomotion velocity, session 11.01.12.11.20.91.11.11.3-1.0-1.11.1-1.11.11.1-1.1-1.11.1-1.20.8-0.9-0.7-0.70.6-1.50.7-0.7-1.01.0-0.9
Locomotion distance, session 13.03.85.42.01.72.22.22.3-2.1-2.02.0-2.02.02.0-2.0-2.02.0-2.01.9-2.2-1.8-2.22.1-1.12.3-2.3-0.7-0.80.9
Locomotion velocity, session 20.30.41.30.80.20.60.71.1-0.6-0.60.6-0.60.60.6-0.7-0.70.7-0.70.4-0.6-0.5-0.50.5-0.10.8-0.80.3-0.30.3
Locomotion distance, session 22.43.45.22.01.62.02.22.3-1.9-1.91.9-1.91.91.9-1.9-2.02.0-2.01.7-2.1-1.7-2.02.0-0.92.2-2.2-0.6-0.70.8
Locomotion velocity, session 33.54.15.42.22.12.22.32.1-2.2-2.22.2-2.22.22.2-2.1-2.12.1-2.12.1-2.2-2.0-2.32.2-1.42.2-2.2-1.0-0.40.5
Locomotion distance, session 34.54.96.42.52.12.42.52.3-2.4-2.42.4-2.42.42.4-2.3-2.42.4-2.32.2-2.5-2.1-2.32.3-1.62.4-2.4-1.2-0.10.1
Stereotopy head waving bouts, day 31.21.42.2-0.9-1.2-1.3-1.2-0.71.31.2-1.21.2-1.2-1.21.11.1-1.11.1-1.41.41.41.5-1.50.4-1.31.30.90.7-0.8
Stereotopy head waving duration, day 30.50.61.2-0.5-0.8-1.0-0.8-0.10.80.7-0.70.7-0.7-0.70.60.6-0.60.6-1.00.90.91.1-1.1-0.1-0.80.80.60.6-0.6
Locomotion velocity, session 70.10.10.40.40.40.60.3-0.1-0.4-0.30.3-0.30.30.3-0.2-0.20.2-0.20.2-0.3-0.1-0.30.3-0.10.1-0.1-0.60.5-0.5
Locomotion distance, session 71.11.42.51.31.41.61.30.7-1.3-1.31.3-1.31.31.3-1.1-1.21.2-1.21.1-1.2-1.0-1.31.2-1.01.0-1.0-1.60.7-0.6
Stereotopy head waving bouts, day 71.11.22.2-0.9-1.1-1.5-1.3-0.91.21.1-1.11.1-1.1-1.10.90.9-0.90.9-1.21.31.11.4-1.40.5-1.31.30.71.0-1.1
Stereotopy head waving duration, day 71.31.52.6-1.1-1.3-1.6-1.4-1.11.31.2-1.21.2-1.2-1.21.11.1-1.11.1-1.31.51.21.6-1.60.5-1.51.50.81.0-1.0
Locomotion velocity, session 80.00.00.3-0.00.10.10.10.10.10.1-0.10.1-0.1-0.10.10.1-0.10.10.00.0-0.00.00.00.5-0.10.10.4-0.10.1
Locomotion distance, session 81.21.82.81.31.41.61.61.3-1.4-1.31.3-1.31.31.3-1.4-1.41.4-1.41.3-1.5-1.2-1.51.5-0.31.7-1.7-0.3-0.70.8
Degree of sensitization distance0.60.61.2-0.8-0.6-0.7-0.9-1.10.80.8-0.80.8-0.8-0.80.90.9-0.90.8-0.80.90.80.8-0.80.5-1.01.0-0.20.4-0.4
Degree of sensitization stereotypy0.40.41.5-0.4-0.5-0.8-0.7-0.60.60.5-0.50.5-0.5-0.50.40.4-0.40.4-0.50.80.40.8-0.80.1-0.90.9-0.01.2-1.2
Conditioned locomotion0.40.53.5-0.0-0.2-0.2-0.30.20.30.2-0.20.2-0.2-0.20.10.1-0.10.1-0.60.60.60.9-0.9-0.7-0.70.7-0.31.8-1.9
Cocaine response after cond. corrected0.60.75.70.1-0.00.20.40.2-0.2-0.10.1-0.10.10.10.10.1-0.10.00.4-0.6-0.4-0.91.01.40.7-0.71.2-2.42.4
Cocaine response after cond. not corrected1.11.23.50.90.71.01.11.1-1.0-0.90.9-0.90.90.9-0.8-0.80.8-0.81.1-1.3-1.1-1.41.50.61.4-1.40.4-1.81.9
Cocaine response before conditioning3.54.26.22.12.02.02.12.2-2.1-2.22.2-2.22.22.2-2.5-2.42.4-2.32.0-1.9-2.0-1.51.4-2.41.8-1.8-2.21.5-1.4
Saline control response0.10.10.2-0.4-0.4-0.3-0.3-0.20.30.3-0.30.3-0.3-0.3-0.00.0-0.00.0-0.50.30.40.4-0.50.4-0.00.00.20.1-0.1
Bone: connectivity density6.39.916.5-3.4-3.6-3.5-3.3-3.33.33.4-3.43.4-3.4-3.43.33.3-3.33.3-3.22.93.02.7-2.54.1-2.42.43.4-2.12.0
Bone: cortical apparent density0.30.41.10.60.50.80.70.7-0.6-0.70.7-0.70.70.7-0.7-0.70.7-0.70.3-0.4-0.2-0.20.1-0.90.4-0.4-0.41.0-1.0
Bone: cortical area9.013.617.6-3.9-4.0-4.1-4.2-4.14.04.0-4.04.0-4.0-4.04.04.0-4.04.0-3.53.83.43.4-3.33.6-3.63.62.8-1.00.9
Bone: cortical porosity1.21.34.00.90.90.90.81.1-1.0-1.31.3-1.31.31.3-1.3-1.31.3-1.30.6-0.9-0.5-0.40.3-2.00.9-0.9-1.71.4-1.4
Bone: cortical porosity1.61.74.51.21.21.11.01.3-1.2-1.51.5-1.51.51.5-1.5-1.51.5-1.50.8-1.1-0.7-0.60.4-2.11.0-1.0-1.81.5-1.5
Bone: cortical thickness3.76.07.9-2.4-2.6-2.7-2.7-2.62.62.8-2.82.8-2.8-2.82.82.8-2.82.8-2.02.41.81.8-1.72.8-2.32.32.1-1.41.3
Bone: cortical thickness0.30.31.2-0.4-0.3-0.4-0.5-0.70.40.6-0.60.6-0.6-0.60.60.6-0.60.6-0.10.30.0-0.00.11.1-0.40.40.4-0.90.9
Bone: cortical tissue density0.40.61.20.70.60.90.90.8-0.7-0.80.8-0.80.80.8-0.8-0.80.8-0.80.4-0.5-0.3-0.30.2-1.00.5-0.5-0.51.1-1.1
Condit. Reinf. active minus inactive responses0.20.21.10.40.10.20.40.7-0.3-0.30.3-0.30.30.3-0.2-0.20.2-0.20.4-0.5-0.4-0.60.60.60.6-0.60.6-1.01.0
Condit. Reinf. active-inactive response ratio0.30.31.8-0.4-0.7-0.4-0.2-0.10.30.4-0.40.4-0.4-0.40.40.4-0.40.4-0.30.10.30.1-0.11.30.1-0.11.3-1.11.1
Condit. Reinf. active responses0.60.71.91.00.80.80.91.4-0.9-0.70.7-0.70.70.7-0.8-0.70.7-0.81.0-1.0-1.0-1.11.10.01.0-1.0-0.1-0.80.8
Condit. Reinf. inactive responses2.42.84.01.92.01.81.72.0-1.8-1.71.7-1.71.71.7-1.8-1.71.7-1.81.8-1.7-1.8-1.61.6-1.71.5-1.5-1.90.6-0.5
Incentive salience index mean0.10.10.8-0.0-0.2-0.1-0.10.10.20.3-0.30.3-0.3-0.30.30.4-0.40.30.00.1-0.0-0.20.20.9-0.10.10.6-0.90.9
Condit. Reinf. lever presses0.30.31.0-0.3-0.3-0.3-0.5-0.30.50.7-0.70.7-0.7-0.70.80.8-0.80.7-0.20.50.30.1-0.01.0-0.60.60.5-0.80.8
Condit. Reinf. active minus inactive responses0.10.10.50.1-0.00.00.00.0-0.1-0.30.3-0.30.30.3-0.2-0.30.3-0.2-0.0-0.10.00.1-0.2-0.60.1-0.1-0.60.7-0.7
Condit. Reinf. active-inactive response ratio0.30.30.50.60.40.50.50.6-0.6-0.60.6-0.60.60.6-0.6-0.60.6-0.60.7-0.6-0.7-0.60.6-0.50.6-0.6-0.6-0.10.1
Condit. Reinf. active responses0.20.31.20.40.50.40.30.2-0.5-0.60.6-0.60.60.6-0.6-0.60.6-0.60.3-0.4-0.3-0.20.1-1.00.4-0.4-1.10.9-0.8
Condit. Reinf. inactive responses0.70.82.10.81.00.80.70.6-0.8-1.01.0-1.01.01.0-1.0-1.01.0-1.00.6-0.6-0.7-0.40.3-1.40.5-0.5-1.41.3-1.3
Condit. Reinf. lever presses0.00.00.2-0.10.0-0.0-0.0-0.3-0.1-0.10.1-0.10.10.1-0.1-0.10.1-0.0-0.0-0.1-0.00.1-0.1-0.30.1-0.1-0.40.2-0.2
Condit. Reinf. lever reinforcers received0.50.71.90.70.80.70.70.5-0.9-1.01.0-1.01.01.0-0.9-0.90.9-0.90.7-0.8-0.7-0.60.5-1.30.7-0.7-1.40.8-0.7
Conditioned reinforcement - actives1.31.32.01.31.21.21.11.0-1.2-1.21.2-1.21.21.2-1.3-1.11.1-1.11.4-1.2-1.4-1.21.2-1.21.0-1.0-1.20.3-0.2
Conditioned reinforcement - inactives1.61.83.31.61.41.41.41.2-1.4-1.31.3-1.31.31.3-1.3-1.21.2-1.21.8-1.5-1.8-1.71.8-0.71.4-1.4-1.1-0.60.7
Conditioned locomotion0.40.41.70.60.60.50.40.2-0.6-0.60.6-0.60.60.6-0.6-0.60.6-0.60.6-0.4-0.6-0.30.3-1.10.2-0.2-1.31.0-1.0
Patch foraging indifference point 0 sec1.93.15.71.81.91.71.61.5-1.9-1.81.8-1.81.81.8-1.8-1.91.9-1.82.0-1.8-2.0-1.81.8-1.61.8-1.8-2.40.2-0.1
Patch foraging indifference point AUC0.20.30.60.50.20.20.30.5-0.4-0.50.5-0.50.50.5-0.7-0.70.7-0.70.3-0.3-0.4-0.20.2-0.70.3-0.3-0.70.7-0.7
Delay disc. indifference point, 0s delay1.21.42.0-1.1-1.4-1.3-1.4-1.11.21.1-1.11.1-1.1-1.11.31.3-1.31.2-1.41.31.41.2-1.20.6-1.41.40.70.2-0.2
Delay disc. indifference point, 16s delay1.11.11.7-1.1-1.0-1.0-1.2-1.31.11.1-1.11.1-1.1-1.11.21.2-1.21.2-1.01.10.90.8-0.80.9-1.11.10.7-0.30.3
Delay disc. indifference point, 2s delay1.11.21.9-1.2-1.1-1.1-1.1-0.91.21.2-1.21.2-1.2-1.21.01.1-1.11.2-1.41.21.41.2-1.20.9-1.11.11.2-0.0-0.0
Delay disc. indifference point, 24s delay1.31.21.7-1.2-1.1-1.2-1.2-1.31.21.3-1.31.3-1.3-1.31.21.1-1.11.2-1.11.21.11.1-1.01.0-1.11.10.8-0.20.2
Delay disc. indifference point, 4s delay0.40.52.7-0.5-0.3-0.3-0.2-0.60.40.5-0.50.5-0.5-0.50.60.6-0.60.7-0.40.20.4-0.10.21.2-0.10.11.1-1.61.6
Delay disc. indifference point, 8s delay2.72.84.6-1.6-1.6-1.6-1.6-1.71.71.8-1.81.8-1.8-1.81.91.9-1.92.0-1.41.41.31.0-0.92.1-1.41.41.9-1.71.6
Indifference point function ln k3.14.45.3-2.3-2.3-2.2-2.3-2.12.32.3-2.32.3-2.3-2.32.32.2-2.22.1-2.32.22.32.2-2.21.7-2.02.01.1-0.20.1
Indifference point function log k3.14.45.3-2.3-2.3-2.2-2.3-2.12.32.3-2.32.3-2.3-2.32.32.2-2.22.1-2.32.22.32.2-2.21.7-2.02.01.1-0.20.1
Patch foraging total patch changes 0 sec1.82.96.11.81.91.71.51.4-1.8-1.81.8-1.81.81.8-1.8-1.91.9-1.81.8-1.7-1.9-1.71.7-1.71.7-1.7-2.50.5-0.4
Patch foraging total patch changes 12 sec1.62.02.91.51.51.41.31.2-1.5-1.51.5-1.51.51.5-1.7-1.61.6-1.51.7-1.3-1.7-1.41.3-1.51.2-1.2-1.50.8-0.7
Patch foraging total patch changes 18 sec3.64.79.12.22.22.11.91.7-2.2-2.32.3-2.32.32.3-2.3-2.52.5-2.51.9-2.0-1.8-1.71.6-2.71.9-1.9-3.01.6-1.5
Patch foraging total patch changes 24 sec1.62.04.61.51.61.41.11.0-1.4-1.41.4-1.41.41.4-1.5-1.61.6-1.51.3-1.1-1.3-1.00.9-1.80.9-0.9-2.11.7-1.6
Patch foraging total patch changes 6 sec2.13.14.11.91.81.71.71.7-1.9-1.81.8-1.81.81.8-2.0-1.91.9-1.92.0-1.8-2.0-1.81.8-1.51.7-1.7-1.90.3-0.2
Patch foraging time to switch 0 sec2.13.24.91.82.12.22.11.9-1.9-1.81.8-1.81.81.8-2.2-2.02.0-1.91.8-1.8-1.7-1.61.5-1.71.7-1.7-1.30.7-0.6
Patch foraging water rate 0 sec2.84.66.6-2.1-2.3-2.4-2.5-2.32.32.3-2.32.3-2.3-2.32.62.4-2.42.3-2.22.32.12.0-2.01.7-2.22.21.2-0.30.2
Patch foraging water rate 12 sec3.45.26.8-2.4-2.4-2.4-2.5-2.52.42.4-2.42.4-2.4-2.42.62.4-2.42.3-2.62.42.52.4-2.41.7-2.32.31.80.1-0.2
Patch foraging water rate 18 sec0.30.41.2-0.7-0.4-0.6-0.7-1.10.70.7-0.70.7-0.7-0.70.90.9-0.90.8-0.60.70.60.5-0.50.5-0.70.70.2-0.10.1
Patch foraging water rate 24 sec3.14.35.7-2.0-2.0-2.2-2.2-1.92.22.1-2.12.1-2.1-2.12.12.1-2.12.0-2.32.32.32.4-2.41.3-2.32.31.80.9-1.0
Patch foraging water rate 6 sec3.55.16.8-2.3-2.3-2.5-2.5-2.32.42.3-2.32.3-2.3-2.32.62.5-2.52.4-2.42.42.32.3-2.31.9-2.42.42.00.0-0.1
Seeking ratio, delayed vs. immediate footshock0.60.74.1-0.5-0.7-0.7-0.4-0.30.50.7-0.70.7-0.7-0.70.70.6-0.60.8-0.10.2-0.1-0.10.21.70.0-0.01.5-2.02.0
Distance traveled before self-admin1.01.12.31.11.21.31.01.0-1.0-1.01.0-1.01.01.0-1.1-1.01.0-1.10.8-0.8-0.7-0.60.6-1.50.6-0.6-1.51.3-1.3
Distance traveled after self-admin0.20.20.30.50.40.50.40.4-0.5-0.30.3-0.30.30.3-0.4-0.50.5-0.60.4-0.5-0.4-0.50.5-0.10.6-0.6-0.2-0.20.3
Extensor digitorum longus weight4.015.822.7-4.3-4.1-3.8-4.2-4.84.34.5-4.54.5-4.5-4.54.44.4-4.44.5-3.64.33.53.6-3.53.1-4.34.32.1-0.50.3
Bone: elastic displacement4.34.86.02.32.42.42.32.5-2.3-2.42.4-2.42.42.4-2.4-2.42.4-2.42.0-2.2-1.9-1.91.8-2.32.1-2.1-2.31.0-0.9
Bone: elastic work0.10.10.5-0.10.10.30.10.1-0.1-0.30.3-0.30.30.3-0.2-0.20.2-0.2-0.3-0.00.40.3-0.4-0.30.1-0.1-0.20.7-0.7
Bone: endosteal estimation6.614.418.4-4.2-4.2-4.0-4.1-4.24.13.9-3.93.9-3.9-3.93.83.8-3.83.8-4.34.14.24.3-4.33.0-3.83.82.70.5-0.7
Bone: endosteal perimeter6.212.816.7-3.9-3.9-4.0-4.0-4.13.93.8-3.83.8-3.8-3.83.83.8-3.83.8-3.63.83.53.7-3.62.9-3.63.62.5-0.1-0.1
Epididymis fat weight0.20.41.1-0.7-0.4-0.4-0.7-1.10.60.6-0.60.6-0.6-0.60.70.8-0.80.8-0.90.51.00.3-0.30.9-0.40.40.6-0.70.7
Delta time in closed arm before/after self-admin0.50.52.9-0.5-0.6-0.6-0.3-0.40.30.4-0.40.4-0.4-0.40.40.4-0.40.5-0.10.1-0.0-0.10.11.20.1-0.11.4-1.71.7
Delta time in open arm before/after self-admin3.63.44.92.22.12.11.92.2-2.0-1.91.9-1.91.91.9-1.9-1.81.8-1.91.9-1.8-1.7-1.71.6-2.01.6-1.6-2.21.1-1.0
Diff in mean of infusions in LGA sessions1.31.42.4-1.3-1.2-1.4-1.1-1.01.21.2-1.21.2-1.2-1.21.21.3-1.31.5-1.11.11.01.0-1.01.4-1.11.11.6-0.90.8
Delay discount exponential model param0.91.02.00.90.80.80.81.0-0.9-1.11.1-1.11.11.1-1.1-1.11.1-1.20.8-0.8-0.8-0.40.4-1.40.8-0.8-1.21.3-1.3
Extinction: sum of active levers before priming0.40.40.8-0.7-0.7-0.7-0.7-0.40.70.6-0.60.6-0.6-0.60.60.6-0.60.5-0.80.70.80.8-0.90.2-0.70.70.20.5-0.6
Active lever presses in extinction session 60.40.41.0-0.7-0.7-0.6-0.5-0.60.60.8-0.80.8-0.8-0.80.50.6-0.60.7-0.40.50.40.4-0.41.0-0.30.31.0-0.70.6
Bone: final force8.814.217.8-4.1-4.2-4.0-4.1-4.04.04.1-4.14.1-4.1-4.14.14.1-4.14.1-3.83.83.73.5-3.43.9-3.43.43.4-1.51.4
Bone: final moment9.014.618.7-4.2-4.3-4.1-4.1-4.04.14.1-4.14.1-4.1-4.14.14.1-4.14.1-4.03.83.93.6-3.54.1-3.33.33.5-1.61.4
Food consumed during 24 hour testing period1.51.84.8-1.4-1.6-1.7-1.3-1.31.31.5-1.51.5-1.5-1.51.21.2-1.21.2-1.01.00.90.8-0.72.2-0.50.51.7-1.71.6
Glucose0.10.20.6-0.4-0.1-0.4-0.5-0.80.40.5-0.50.5-0.5-0.50.60.5-0.50.5-0.20.50.10.3-0.30.2-0.60.60.40.3-0.3
Heart weight0.10.21.6-0.2-0.3-0.3-0.00.10.10.3-0.30.3-0.3-0.3-0.00.1-0.10.10.2-0.1-0.3-0.10.10.80.3-0.31.3-0.90.9
Delay discount hyperbolic model param0.90.91.80.90.70.80.81.0-0.9-1.01.0-1.01.01.0-1.0-1.01.0-1.20.9-0.7-0.8-0.50.4-1.30.7-0.7-1.21.2-1.2
Intermittent access intake day 1-15 change1.21.22.31.21.21.21.30.8-1.2-1.01.0-1.01.01.0-1.0-0.90.9-0.91.5-1.3-1.5-1.51.5-0.31.1-1.1-0.6-0.80.8
Intermittent access intake escalation0.90.92.01.01.01.01.10.7-1.0-0.80.8-0.80.80.8-0.8-0.70.7-0.71.3-1.1-1.4-1.41.4-0.01.0-1.0-0.4-1.01.0
Intermittent access intake escalation 21.31.32.61.31.31.31.31.0-1.2-1.01.0-1.01.01.0-1.0-0.90.9-0.91.6-1.3-1.6-1.61.6-0.31.2-1.2-0.8-0.90.9
Intermitt. access day 1 inactive lever presses3.23.47.81.71.91.91.71.8-1.7-2.02.0-2.02.02.0-2.0-2.02.0-2.01.1-1.4-1.0-0.90.7-2.81.3-1.3-2.52.3-2.3
Intermitt. access day 15 inactive lever presses1.21.32.11.11.31.41.10.9-1.1-1.21.2-1.21.21.2-1.2-1.31.3-1.30.8-1.0-0.7-0.80.8-1.41.0-1.0-1.51.0-0.9
Intermitt. access escalation Index0.20.20.60.30.70.60.60.3-0.4-0.40.4-0.40.40.4-0.5-0.50.5-0.50.3-0.3-0.2-0.20.1-0.70.3-0.3-0.50.8-0.8
Intermittent access day 1 total infusions1.11.22.01.21.11.01.11.2-1.2-1.11.1-1.11.11.1-1.2-1.11.1-1.11.4-1.2-1.4-1.31.3-0.71.2-1.2-0.6-0.30.3
Intermittent access day 15 total infusions2.12.44.11.71.71.71.71.3-1.7-1.51.5-1.51.51.5-1.6-1.41.4-1.42.0-1.7-2.0-1.91.9-1.01.5-1.5-1.4-0.30.3
Intermittent access terminal intake (last 3 days)2.32.64.01.71.71.71.71.4-1.7-1.71.7-1.71.71.7-1.6-1.51.5-1.52.0-1.8-2.0-1.91.9-1.11.6-1.6-1.4-0.20.3
Intermittent access total infusions2.12.33.71.71.71.71.71.4-1.7-1.51.5-1.51.51.5-1.6-1.51.5-1.41.9-1.7-1.9-1.81.8-1.11.4-1.4-1.4-0.10.2
Intermittent access day 1 locomotion0.90.92.70.81.01.00.80.6-0.9-1.01.0-1.01.01.0-0.9-0.90.9-0.90.6-0.6-0.5-0.40.3-1.60.5-0.5-1.31.5-1.5
Intermittent access day 15 total locomotion1.21.33.61.11.31.20.90.4-1.1-1.21.2-1.21.21.2-1.0-1.01.0-1.01.1-0.8-1.0-0.80.7-1.90.4-0.4-1.91.6-1.6
Intermittent access total locomotion2.83.27.81.71.91.91.51.1-1.7-1.91.9-1.91.91.9-1.7-1.71.7-1.71.5-1.3-1.4-1.21.0-2.81.0-1.0-2.72.3-2.2
Intermittent access standard deviation0.50.51.30.80.80.80.90.9-0.7-0.60.6-0.60.60.6-0.7-0.60.6-0.61.1-0.8-1.1-1.01.0-0.10.7-0.7-0.4-0.60.6
Left kidney weight0.51.57.3-0.9-1.1-1.1-0.8-0.90.81.1-1.11.1-1.1-1.11.01.1-1.11.2-0.40.40.20.00.12.4-0.20.21.8-2.72.7
Right kidney weight2.57.08.9-2.8-2.8-2.9-2.9-3.02.82.9-2.92.9-2.9-2.92.83.0-3.02.9-2.52.72.42.5-2.42.5-2.72.72.2-0.60.5
Cocaine induced anxiety1.11.31.9-1.2-1.1-1.1-1.1-1.31.21.2-1.21.2-1.2-1.21.11.2-1.21.2-1.11.21.01.2-1.20.7-1.41.40.30.4-0.5
Post-drug Anxiety4.24.75.8-2.4-2.3-2.3-2.3-2.22.42.4-2.42.4-2.4-2.42.22.2-2.22.2-2.32.42.22.4-2.41.7-2.22.21.60.1-0.3
Baseline Anxiety0.91.01.7-1.0-1.0-1.0-1.0-0.91.01.1-1.11.1-1.1-1.11.20.9-0.90.9-1.00.91.00.8-0.71.2-0.70.71.3-0.70.7
Tail length0.10.20.50.40.60.50.3-0.1-0.4-0.40.4-0.40.40.4-0.3-0.30.3-0.30.4-0.3-0.3-0.40.4-0.70.1-0.1-0.60.6-0.5
Length with tail1.86.610.0-2.8-2.6-2.6-2.7-3.22.72.8-2.82.8-2.8-2.82.72.6-2.62.7-2.72.72.72.5-2.42.4-2.52.52.5-0.40.3
Length without tail6.714.619.0-4.2-4.1-4.0-3.8-4.14.04.3-4.34.3-4.3-4.33.94.0-4.04.0-3.73.73.53.3-3.24.4-3.33.34.3-2.01.8
Times rat made contact with spout0.30.31.80.30.30.10.10.2-0.3-0.00.0-0.00.00.0-0.1-0.20.2-0.20.7-0.4-0.7-0.80.90.60.5-0.5-0.4-1.31.3
Lifetime Intake1.82.03.81.61.61.61.51.2-1.6-1.31.3-1.31.31.3-1.4-1.31.3-1.31.9-1.6-1.9-1.81.8-1.01.3-1.3-1.3-0.30.3
Liver weight, left1.82.94.9-2.0-1.7-1.8-1.8-2.21.81.8-1.81.8-1.8-1.81.91.9-1.92.0-1.61.71.51.5-1.41.9-1.71.71.2-0.50.5
Liver weight, right1.52.54.3-1.8-1.5-1.6-1.7-2.11.61.6-1.61.6-1.6-1.61.81.8-1.81.8-1.61.61.61.4-1.41.7-1.71.71.0-0.30.2
Locomotor activity0.81.32.11.41.31.21.11.2-1.2-1.21.2-1.21.21.2-1.2-1.01.0-1.01.3-1.0-1.3-1.11.1-1.10.7-0.7-1.40.8-0.7
Locomotor testing distance2.33.85.52.32.22.12.02.0-2.1-2.12.1-2.12.12.1-2.1-1.91.9-2.02.1-1.9-2.1-1.91.9-1.91.6-1.6-1.91.0-0.9
Locomotor testing rearing1.82.84.11.92.02.01.81.5-1.8-1.81.8-1.81.81.8-1.9-1.71.7-1.81.7-1.5-1.7-1.41.3-2.01.1-1.1-1.51.7-1.6
Locomotion in novel chamber0.50.71.2-0.8-0.9-0.9-0.8-1.00.90.8-0.80.8-0.8-0.80.90.9-0.90.7-0.90.90.90.9-0.90.4-1.11.10.40.2-0.2
Locomotion in novel chamber post-restriction0.10.10.5-0.2-0.1-0.1-0.4-0.60.30.1-0.10.1-0.1-0.10.60.3-0.30.2-0.60.30.70.2-0.3-0.0-0.40.40.20.3-0.3
Fecal boli incidents, locomotor time 12.72.98.81.51.61.41.51.3-1.6-1.31.3-1.31.31.3-0.9-1.01.0-1.02.0-2.0-2.0-2.62.70.62.0-2.00.4-2.93.0
Change in fecal boli incidents, locomotor task1.11.02.1-1.1-1.0-1.1-1.1-0.71.11.0-1.01.0-1.0-1.00.91.0-1.01.0-1.41.21.41.4-1.50.2-1.11.10.30.6-0.6
Time >=10cm from walls, locomotor time 10.40.41.3-0.5-0.3-0.4-0.4-0.80.40.4-0.40.4-0.4-0.40.80.7-0.70.6-0.40.30.4-0.00.11.1-0.20.21.1-1.11.2
Bouts of movement, locomotor time 10.20.20.8-0.1-0.00.1-0.1-0.30.10.0-0.00.0-0.0-0.00.60.5-0.50.40.1-0.00.0-0.30.30.9-0.10.10.7-0.90.9
Total resting periods, locomotor time 10.20.30.90.40.50.60.40.3-0.4-0.40.4-0.40.40.40.0-0.00.0-0.20.6-0.5-0.5-0.80.80.50.5-0.50.3-0.91.0
Rest time, locomotor task time 10.30.40.90.60.70.60.50.4-0.6-0.50.5-0.50.50.5-0.2-0.30.3-0.30.7-0.7-0.7-0.91.00.30.6-0.60.2-0.91.0
Distance moved, locomotor task time 10.10.10.8-0.2-0.2-0.1-0.00.00.1-0.10.1-0.10.10.1-0.5-0.20.2-0.1-0.20.10.20.5-0.5-0.7-0.10.1-0.40.9-0.9
Vertical activity count, locomotor time 11.21.32.2-1.1-1.3-1.2-1.1-1.11.11.3-1.31.3-1.3-1.31.11.3-1.31.3-0.80.90.70.7-0.71.5-0.90.91.5-1.31.2
Time >=10cm from walls, locomotor time 20.40.40.80.90.80.70.70.8-0.7-0.70.7-0.70.70.7-0.5-0.50.5-0.50.7-0.7-0.7-0.90.9-0.50.5-0.5-0.5-0.10.2
Bouts of movement, locomotor time 22.62.84.2-1.7-1.6-1.6-1.8-1.61.81.7-1.71.7-1.7-1.71.81.8-1.81.8-1.91.91.81.9-1.90.6-2.02.00.40.7-0.8
Total resting periods, locomotor time 22.93.14.6-1.8-1.7-1.7-1.9-1.71.91.7-1.71.7-1.7-1.71.91.9-1.91.9-2.02.02.02.0-2.10.8-2.12.10.60.8-0.8
Rest time, locomotor task time 20.10.20.6-0.30.1-0.0-0.1-0.60.20.3-0.30.3-0.3-0.30.60.5-0.50.5-0.20.20.2-0.10.10.8-0.30.30.8-0.60.6
Distance moved, locomotor task time 20.20.20.80.30.10.30.30.6-0.4-0.50.5-0.50.50.5-0.7-0.60.6-0.60.3-0.3-0.3-0.10.0-0.90.4-0.4-0.80.5-0.5
Vertical activity count, locomotor time 20.10.10.2-0.1-0.4-0.3-0.4-0.40.20.3-0.30.3-0.3-0.30.30.3-0.30.2-0.10.20.10.1-0.1-0.1-0.30.3-0.30.0-0.0
Light reinforcement 12.44.49.22.02.22.21.91.4-2.1-2.32.3-2.32.32.3-2.2-2.22.2-2.21.9-1.7-1.7-1.51.3-3.01.3-1.3-2.62.4-2.3
Light reinforcement 20.70.91.61.01.11.11.00.6-1.0-1.21.2-1.21.21.2-0.9-0.80.8-0.91.1-1.0-1.0-1.01.0-1.10.7-0.7-1.30.3-0.3
Bone: marrow area6.514.118.1-4.2-4.1-4.0-4.1-4.14.13.9-3.93.9-3.9-3.93.83.8-3.83.8-4.34.14.24.2-4.22.9-3.83.82.60.6-0.7
Bone: maximum diameter3.86.99.8-2.7-2.8-3.0-3.1-3.12.82.9-2.92.9-2.9-2.92.92.9-2.92.9-2.42.82.22.5-2.42.3-2.82.81.5-0.20.1
Bone: maximum force12.120.826.4-5.1-5.0-4.8-4.9-5.04.94.8-4.84.8-4.8-4.84.84.8-4.84.8-5.14.75.04.7-4.64.3-4.24.23.8-0.80.6
Bone: maximum moment12.221.127.1-5.2-5.1-4.8-4.9-5.04.94.8-4.84.8-4.8-4.84.84.8-4.84.8-5.24.75.14.8-4.74.4-4.24.23.9-0.80.7
Mean time between licks in bursts0.20.20.80.50.40.60.60.9-0.4-0.50.5-0.50.50.5-0.6-0.50.5-0.5-0.0-0.40.1-0.10.0-0.60.5-0.5-0.50.4-0.4
Mean num. licks in bursts0.60.76.00.1-0.1-0.00.20.5-0.2-0.20.2-0.20.20.2-0.1-0.10.1-0.10.3-0.6-0.3-0.70.81.41.0-1.01.2-2.42.4
Cd content in liver0.40.51.00.80.81.00.80.4-0.7-0.60.6-0.60.60.6-0.6-0.60.6-0.60.9-0.7-0.9-0.90.9-0.30.6-0.6-0.7-0.10.1
Co content in liver0.30.41.80.70.80.60.50.1-0.5-0.00.0-0.00.00.0-0.1-0.10.1-0.11.2-0.4-1.4-1.11.2-0.40.1-0.1-0.8-0.50.5
Cu content in liver0.81.01.7-0.9-0.4-0.8-0.9-0.81.01.3-1.31.3-1.3-1.31.31.2-1.21.2-0.50.90.50.6-0.51.2-1.11.11.0-0.60.6
Fe content in liver0.20.31.00.50.90.50.50.3-0.5-0.30.3-0.30.30.3-0.3-0.30.3-0.31.0-0.5-1.0-0.80.9-0.20.3-0.3-0.6-0.30.3
K content in liver0.40.41.4-0.5-0.1-0.4-0.5-0.50.50.7-0.70.7-0.7-0.70.70.7-0.70.7-0.20.40.20.10.01.2-0.50.50.9-1.01.0
Mg content in liver0.10.10.60.20.10.00.00.1-0.00.0-0.00.0-0.0-0.00.00.0-0.00.00.2-0.1-0.2-0.30.40.50.1-0.10.5-0.80.8
Mn content in liver0.10.10.8-0.2-0.2-0.3-0.20.00.2-0.10.1-0.10.10.10.10.1-0.10.1-0.50.30.60.6-0.7-0.3-0.30.30.40.9-0.9
Na content in liver0.00.00.20.10.40.50.30.0-0.10.0-0.00.0-0.0-0.0-0.10.0-0.00.00.2-0.0-0.1-0.10.1-0.0-0.10.1-0.20.4-0.4
Rb content in liver0.20.20.60.60.70.60.40.2-0.5-0.40.4-0.40.40.4-0.3-0.30.3-0.30.6-0.4-0.5-0.60.7-0.70.2-0.2-0.50.2-0.1
Se content in liver0.50.61.30.91.00.60.70.7-0.8-0.70.7-0.70.70.7-0.7-0.70.7-0.71.1-0.9-1.1-1.11.2-0.40.8-0.8-0.1-0.70.7
Sr content in liver0.60.51.3-0.6-0.8-0.8-1.0-1.10.70.8-0.80.8-0.8-0.80.80.8-0.80.8-0.60.70.50.4-0.40.3-0.80.8-0.0-0.20.1
Zn content in liver1.21.32.81.41.41.21.10.8-1.2-1.01.0-1.01.01.0-1.0-1.11.1-1.11.4-1.0-1.4-1.21.2-1.70.8-0.8-1.70.8-0.7
Bone: minimum diameter8.215.318.8-4.2-4.3-4.3-4.3-4.34.24.2-4.24.2-4.2-4.24.14.1-4.14.1-4.14.24.04.1-4.13.3-4.04.03.10.2-0.4
Time in familiar zone, hab. session 10.50.50.80.70.60.50.70.9-0.6-0.50.5-0.50.50.5-0.6-0.60.6-0.60.7-0.8-0.8-0.80.80.10.9-0.90.1-0.80.9
Time in novel zone, hab. session 10.70.62.2-0.6-0.5-0.7-0.8-0.80.70.5-0.50.5-0.5-0.50.60.6-0.60.5-0.80.90.81.0-1.1-0.4-1.11.1-0.41.5-1.5
Total zone transitions, hab. session 10.30.40.90.70.70.80.60.6-0.7-0.70.7-0.70.70.7-0.6-0.70.7-0.70.5-0.6-0.4-0.60.5-0.80.5-0.5-1.00.4-0.4
Total locomotion distance, hab. session 10.00.00.20.0-0.10.20.20.2-0.0-0.10.1-0.10.10.1-0.1-0.10.1-0.1-0.3-0.10.40.1-0.10.00.3-0.30.3-0.20.2
Locomotion velocity, hab. session 10.00.00.2-0.1-0.20.10.10.10.10.0-0.00.0-0.0-0.0-0.0-0.00.0-0.0-0.40.00.50.2-0.20.10.1-0.10.3-0.00.0
Time in familiar zone, hab. session 20.30.31.2-0.5-0.5-0.5-0.5-0.20.40.5-0.50.5-0.5-0.50.40.4-0.40.4-0.40.20.30.2-0.10.90.0-0.00.6-1.11.1
Time in novel zone, hab. session 20.60.64.30.30.50.50.40.1-0.3-0.50.5-0.50.50.5-0.5-0.50.5-0.40.10.0-0.10.2-0.3-1.4-0.30.3-0.92.1-2.1
Total zone transitions, hab. session 20.40.51.00.70.50.80.70.7-0.7-0.60.6-0.60.60.6-0.4-0.50.5-0.50.6-0.8-0.6-1.01.0-0.00.8-0.8-0.2-0.90.9
Total locomotion distance, hab. session 20.20.20.50.50.30.60.60.7-0.4-0.50.5-0.50.50.5-0.4-0.40.4-0.40.0-0.60.0-0.50.50.10.7-0.70.3-0.70.7
Locomotion velocity, hab. session 20.10.20.80.30.10.40.50.6-0.3-0.30.3-0.30.30.3-0.2-0.20.2-0.2-0.0-0.40.1-0.40.40.30.6-0.60.5-0.90.9
Novel to familiar place preference ratio1.81.93.0-1.6-1.3-1.3-1.5-1.71.51.3-1.31.3-1.3-1.31.31.3-1.31.3-1.41.61.31.6-1.70.7-1.61.60.31.0-1.0
Novelty place preference1.41.42.4-1.4-1.1-1.1-1.3-1.61.21.1-1.11.1-1.1-1.11.11.1-1.11.1-1.21.41.11.5-1.50.5-1.51.50.11.2-1.2
Time in novel zone, NPP test1.31.32.4-1.3-0.9-1.0-1.3-1.51.11.0-1.01.0-1.0-1.01.00.9-0.91.0-1.11.41.11.5-1.60.2-1.41.4-0.21.5-1.5
Total zone transitions, NPP test1.31.93.41.51.21.61.51.6-1.4-1.31.3-1.31.31.3-1.1-1.21.2-1.21.5-1.6-1.4-1.81.8-0.41.6-1.6-0.5-1.21.3
Total locomotion distance, NPP test1.72.33.41.71.31.81.81.8-1.6-1.61.6-1.61.61.6-1.6-1.61.6-1.61.3-1.7-1.2-1.61.6-1.01.8-1.8-0.8-0.40.5
Locomotion velocity, NPP test1.01.42.21.30.91.41.41.5-1.2-1.21.2-1.21.21.2-1.1-1.11.1-1.21.0-1.4-0.9-1.41.4-0.51.5-1.5-0.3-0.90.9
Intraocular pressure6.89.511.93.43.23.33.33.4-3.2-3.33.3-3.33.33.3-3.3-3.43.4-3.33.0-3.1-2.8-2.82.7-3.22.9-2.9-2.91.2-1.1
Delta distance traveled before/after self-admin0.30.31.8-0.2-0.3-0.3-0.1-0.20.20.3-0.30.3-0.3-0.30.40.2-0.20.3-0.0-0.1-0.0-0.20.31.10.3-0.31.1-1.41.4
Delta ambulatory time before/after self-admin0.10.10.8-0.0-0.1-0.1-0.1-0.10.00.2-0.20.2-0.2-0.20.20.1-0.10.20.1-0.1-0.1-0.30.30.60.2-0.20.5-0.90.9
Parametrial fat weight1.83.65.12.02.12.01.91.9-2.0-1.91.9-1.91.91.9-1.9-1.91.9-1.92.0-2.1-2.0-2.22.2-1.32.1-2.1-1.3-0.60.7
Pavlov. Cond. lever latency0.10.21.0-0.4-0.10.00.1-0.00.1-0.20.2-0.20.20.2-0.2-0.30.3-0.2-0.60.20.70.7-0.8-0.40.0-0.00.31.0-1.0
Pavlov. Cond. magazine entry latency0.10.21.3-0.0-0.1-0.1-0.00.0-0.1-0.00.0-0.00.00.00.00.0-0.0-0.00.2-0.3-0.3-0.40.40.70.4-0.40.5-1.11.1
Pavlov. Cond. change in total contacts0.10.10.5-0.1-0.2-0.4-0.4-0.10.20.5-0.50.5-0.5-0.50.30.4-0.40.40.30.2-0.4-0.20.20.5-0.30.30.1-0.70.7
Pavlov. Cond. index score0.20.20.6-0.1-0.2-0.4-0.5-0.40.30.5-0.50.5-0.5-0.50.60.6-0.60.60.20.2-0.3-0.20.30.7-0.40.40.1-0.80.8
Pavlov. Cond. latency score0.20.20.9-0.0-0.2-0.3-0.4-0.40.20.4-0.40.4-0.4-0.40.50.6-0.60.50.30.1-0.4-0.30.40.7-0.30.30.1-1.00.9
Pavlov. Cond. lever contacts0.30.41.40.70.60.50.30.4-0.5-0.30.3-0.30.30.3-0.3-0.20.2-0.21.1-0.6-1.2-1.11.2-0.10.4-0.4-0.9-0.90.9
Pavlov. Cond. magazine entry number0.10.10.6-0.1-0.1-0.0-0.00.00.10.0-0.00.0-0.0-0.0-0.1-0.10.1-0.0-0.50.20.50.5-0.5-0.4-0.20.2-0.10.8-0.8
Pavlov. Cond. intertrial magazine entries0.40.51.50.80.50.70.91.2-0.7-0.60.6-0.60.60.6-0.7-0.60.6-0.60.6-0.8-0.6-0.70.7-0.20.8-0.80.3-0.50.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.4-0.5-0.7-0.7-0.70.60.8-0.80.8-0.8-0.80.90.9-0.90.9-0.00.5-0.00.00.11.1-0.60.60.4-1.01.0
Pavlov. Cond. response bias0.20.21.50.30.10.10.10.2-0.3-0.10.1-0.10.10.1-0.1-0.00.0-0.10.6-0.4-0.7-0.70.80.50.4-0.40.0-1.21.2
Pavlov. Cond. lever latency0.00.00.1-0.1-0.2-0.1-0.00.20.0-0.00.0-0.00.00.0-0.00.0-0.0-0.0-0.20.10.20.2-0.20.1-0.00.00.10.1-0.1
Pavlov. Cond. magazine entry latency0.81.01.6-1.2-1.2-1.2-1.1-1.11.11.0-1.01.0-1.0-1.00.90.9-0.91.0-1.11.01.01.1-1.10.8-0.80.81.0-0.10.0
Pavlov. Cond. change in total contacts1.41.92.8-1.5-1.2-1.5-1.5-1.71.41.7-1.71.7-1.7-1.71.51.5-1.51.6-0.91.30.80.9-0.81.4-1.21.21.1-1.21.1
Pavlov. Cond. index score0.40.61.0-0.9-0.7-0.9-0.9-1.00.80.9-0.90.9-0.9-0.90.80.8-0.80.8-0.60.80.50.7-0.60.6-0.70.70.6-0.30.2
Pavlov. Cond. latency score0.50.61.0-0.9-0.8-1.0-0.9-1.00.90.9-0.90.9-0.9-0.90.90.8-0.80.9-0.60.80.60.7-0.60.7-0.70.70.7-0.40.4
Pavlov. Cond. lever contacts0.10.10.30.30.50.40.30.1-0.4-0.30.3-0.30.30.3-0.3-0.30.3-0.30.5-0.4-0.5-0.50.5-0.20.3-0.3-0.2-0.20.3
Pavlov. Cond. magazine entry number2.12.53.91.81.61.71.72.0-1.7-1.71.7-1.71.71.7-1.6-1.71.7-1.71.6-1.7-1.5-1.71.7-0.91.7-1.7-1.2-0.20.3
Pavlov. Cond. intertrial magazine entries4.25.57.62.82.52.32.52.7-2.6-2.52.5-2.52.52.5-2.4-2.42.4-2.52.7-2.6-2.7-2.72.7-1.42.4-2.4-1.4-0.20.3
Pavlov. Cond. lever-magazine prob. diff.0.81.01.6-1.2-0.9-1.2-1.2-1.31.11.1-1.11.1-1.1-1.11.01.0-1.01.1-0.91.10.81.0-1.00.7-1.01.00.8-0.10.0
Pavlov. Cond. response bias0.00.00.0-0.00.20.0-0.0-0.2-0.00.0-0.00.0-0.0-0.0-0.1-0.10.1-0.00.2-0.0-0.2-0.10.1-0.10.1-0.1-0.1-0.00.0
Time in closed arm before self-admin1.51.72.8-1.3-1.2-1.3-1.4-1.31.41.4-1.41.4-1.4-1.41.01.0-1.01.1-1.41.51.41.7-1.70.3-1.51.50.21.2-1.3
Time in closed arm after self-admin0.50.50.9-0.9-0.9-0.9-0.8-0.90.80.8-0.80.8-0.8-0.80.60.5-0.50.7-0.90.80.80.9-0.90.5-0.60.60.70.0-0.0
Time in open arm before self-admin0.70.71.7-1.1-0.8-0.8-0.9-1.30.90.7-0.70.7-0.7-0.71.11.0-1.01.0-1.00.91.10.8-0.90.6-0.90.90.8-0.10.1
Time in open arm after self-admin0.20.20.50.60.60.60.50.7-0.5-0.50.5-0.50.50.5-0.3-0.30.3-0.50.5-0.4-0.4-0.30.3-0.60.2-0.2-0.70.5-0.5
Bone: periosteal estimation10.722.127.5-5.1-5.2-5.2-5.2-5.25.15.0-5.05.0-5.0-5.05.05.0-5.05.0-4.95.04.74.8-4.64.2-4.64.63.6-0.40.3
Bone: periosteal perimeter9.215.319.4-4.2-4.3-4.4-4.4-4.44.24.3-4.34.3-4.3-4.34.24.2-4.24.2-3.84.03.63.7-3.53.8-3.73.73.2-1.21.1
Bone: post-yield work7.29.814.5-3.5-3.5-3.2-3.3-3.43.43.1-3.13.1-3.1-3.13.13.1-3.13.1-3.83.53.73.8-3.82.2-3.23.22.31.0-1.1
Progressive ratio test 1 active lever presses3.33.54.62.02.12.11.91.5-2.0-2.02.0-2.02.02.0-1.9-1.91.9-1.92.1-1.8-2.0-1.91.8-2.01.6-1.6-1.90.9-0.8
Progressive ratio test 1 breakpoint3.03.14.11.92.02.01.81.4-1.9-1.91.9-1.91.91.9-1.7-1.81.8-1.82.0-1.7-2.0-1.81.8-2.01.5-1.5-1.90.9-0.8
Progressive ratio test 1 inactive lever presses2.93.24.21.92.02.01.81.4-1.9-1.91.9-1.91.91.9-1.8-1.91.9-1.91.8-1.7-1.7-1.71.6-2.01.6-1.6-2.00.9-0.9
Progressive ratio test 2 active lever presses1.81.93.31.51.81.81.40.9-1.4-1.41.4-1.41.41.4-1.4-1.31.3-1.21.4-1.2-1.3-1.21.2-1.80.9-0.9-1.81.2-1.1
Progressive ratio test 2 breakpoint2.32.64.41.72.02.01.71.2-1.7-1.71.7-1.71.71.7-1.7-1.51.5-1.51.7-1.4-1.5-1.41.4-2.01.1-1.1-2.11.3-1.2
Progressive ratio test 2 inactive lever presses2.32.74.31.71.91.91.81.5-1.7-1.71.7-1.71.71.7-1.9-1.61.6-1.61.7-1.5-1.7-1.41.3-1.91.3-1.3-2.11.0-1.0
Incentive Sensitization - Responses0.10.10.2-0.1-0.1-0.1-0.2-0.40.20.2-0.20.2-0.2-0.20.20.4-0.40.4-0.00.20.00.1-0.1-0.0-0.40.4-0.40.2-0.3
Incentive Sensitization - Breakpoint0.00.00.30.10.10.1-0.0-0.30.10.0-0.00.0-0.0-0.00.00.2-0.20.20.10.1-0.10.1-0.1-0.2-0.30.3-0.60.3-0.3
Sum of active levers in priming session hrs 5-60.10.10.20.10.30.30.30.3-0.3-0.30.3-0.30.30.3-0.5-0.40.4-0.40.2-0.3-0.2-0.10.1-0.30.4-0.4-0.00.0-0.0
Progressive ratio0.10.10.40.20.00.00.1-0.1-0.2-0.20.2-0.20.20.2-0.2-0.20.2-0.20.4-0.3-0.5-0.40.50.10.3-0.30.2-0.70.7
Food seeking constrained by brief footshock0.20.20.60.60.50.60.50.3-0.5-0.50.5-0.50.50.5-0.2-0.30.3-0.50.7-0.5-0.6-0.80.8-0.10.6-0.6-0.2-0.30.3
Seeking ratio, punishment vs. effort0.00.00.20.00.20.20.10.20.00.0-0.00.0-0.0-0.00.20.1-0.10.1-0.10.10.20.1-0.1-0.2-0.10.1-0.30.5-0.5
Retroperitoneal fat weight0.51.64.41.31.21.21.20.9-1.2-0.80.8-0.80.80.8-0.9-0.80.8-0.71.7-1.5-1.7-2.02.10.31.3-1.30.0-2.02.0
Reaction time number correct1.01.53.7-1.2-1.6-1.6-1.2-0.61.31.1-1.11.1-1.1-1.11.01.0-1.01.0-1.51.31.41.6-1.71.0-1.01.01.90.3-0.4
Reaction time mean minus median7.710.213.73.33.43.23.43.2-3.5-3.33.3-3.33.33.3-3.3-3.33.3-3.23.7-3.6-3.7-3.73.7-1.93.6-3.6-1.3-1.11.3
Reaction time mean minus median AUC5.67.39.32.73.02.83.02.6-2.9-2.92.9-2.92.92.9-2.8-2.82.8-2.73.0-3.1-3.0-3.03.0-1.63.0-3.0-0.8-0.80.9
Reaction time num false alarms1.72.33.21.61.41.41.61.7-1.6-1.61.6-1.61.61.6-1.8-1.71.7-1.71.5-1.6-1.6-1.41.4-1.21.7-1.7-0.60.00.0
Reaction time num false alarms AUC2.53.54.91.91.81.82.02.0-2.0-2.02.0-2.02.02.0-2.2-2.12.1-2.11.9-2.1-2.0-1.91.9-1.12.2-2.2-0.6-0.40.5
Reaction time trials correct on left1.01.53.7-1.2-1.6-1.6-1.2-0.61.31.1-1.11.1-1.1-1.11.01.0-1.01.0-1.51.31.41.6-1.71.0-1.01.01.90.3-0.4
Reaction time trials on left0.81.13.4-1.0-1.4-1.4-1.0-0.51.11.0-1.01.0-1.0-1.00.90.8-0.80.8-1.31.11.21.4-1.50.9-0.80.81.80.3-0.4
Reaction time mean0.50.71.60.81.10.90.90.6-0.9-0.80.8-0.80.80.8-0.7-0.60.6-0.61.1-1.0-1.0-1.21.2-0.20.8-0.80.5-0.70.8
Reaction time mean AUC0.40.51.20.60.80.70.70.5-0.7-0.50.5-0.50.50.5-0.4-0.40.4-0.30.9-0.8-0.9-1.01.10.20.7-0.70.8-1.01.0
Median of all reaction times0.10.11.0-0.20.0-0.1-0.1-0.50.20.3-0.30.3-0.3-0.30.40.5-0.50.5-0.10.10.1-0.10.10.5-0.30.31.0-0.60.6
Reaction time omissions8.611.814.43.73.63.63.83.6-3.8-3.83.8-3.83.83.8-3.6-3.63.6-3.53.7-3.8-3.6-3.73.6-2.73.5-3.5-1.8-0.00.2
Reaction time false alarm rate2.53.54.41.92.02.02.01.8-2.0-1.91.9-1.91.91.9-2.0-2.02.0-2.02.1-2.1-2.1-2.12.1-1.22.1-2.1-1.3-0.50.6
Reaction time premature initiation rate5.06.79.02.93.02.92.72.5-2.8-2.62.6-2.62.62.6-2.8-2.82.8-2.73.0-2.5-2.9-2.62.6-2.62.2-2.2-2.61.1-1.0
Reaction time premature initiations2.53.54.82.12.01.92.02.0-2.0-1.91.9-1.91.91.9-2.1-2.22.2-2.12.0-1.8-2.0-1.71.6-2.01.7-1.7-1.51.2-1.1
Std. dev. reaction times5.57.710.42.93.12.93.12.8-3.0-2.92.9-2.92.92.9-2.8-2.82.8-2.73.1-3.1-3.1-3.23.2-1.83.1-3.1-0.6-0.91.0
Reaction time trials completed0.81.13.4-1.0-1.4-1.4-1.0-0.51.11.0-1.01.0-1.0-1.00.90.8-0.80.8-1.31.11.21.4-1.50.9-0.80.81.80.3-0.4
Reaction time trials AUC1.31.94.3-1.4-1.7-1.7-1.4-0.81.51.3-1.31.3-1.3-1.31.21.1-1.11.2-1.71.51.61.8-1.81.1-1.11.12.10.4-0.4
Run reversals in cocaine runway, females0.10.10.3-0.0-0.0-0.00.00.1-0.1-0.20.2-0.20.20.2-0.2-0.10.1-0.10.10.0-0.10.2-0.2-0.50.0-0.0-0.40.6-0.6
Run reversals in cocaine runway, males1.31.21.61.31.11.11.11.3-1.2-1.21.2-1.21.21.2-1.2-1.11.1-1.11.2-1.1-1.1-1.01.0-1.10.9-0.9-1.20.5-0.4
Latency to leave start box in cocaine runway0.00.00.10.1-0.0-0.0-0.0-0.1-0.1-0.10.1-0.10.10.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.30.0-0.0-0.40.1-0.1
Latency to leave start box in cocaine runway, F1.61.73.01.41.41.41.31.2-1.4-1.41.4-1.41.41.4-1.5-1.51.5-1.51.0-1.2-0.9-1.00.9-1.71.1-1.1-1.71.2-1.1
Latency to leave start box in cocaine runway, M1.81.72.4-1.4-1.5-1.5-1.4-1.31.41.4-1.41.4-1.4-1.41.41.5-1.51.4-1.21.21.11.0-1.01.4-1.11.11.4-1.01.0
Std. dev. time between licks in bursts0.81.02.51.21.11.11.11.1-1.0-1.01.0-1.01.01.0-1.0-1.01.0-1.00.9-0.9-0.9-0.80.8-1.60.7-0.7-1.00.9-0.8
Total sessions with >9 infusions0.50.51.70.90.80.80.60.2-0.8-0.60.6-0.60.60.6-0.5-0.50.5-0.51.3-0.8-1.3-1.21.2-0.30.5-0.5-0.6-0.40.4
Short access day 1 total inactive lever presses1.01.12.01.21.41.31.20.8-1.2-1.01.0-1.01.01.0-1.0-1.01.0-1.01.3-1.1-1.3-1.31.3-0.90.9-0.9-1.20.1-0.1
Short access day 10 total inactive lever presses0.60.73.30.40.70.80.60.7-0.5-0.70.7-0.70.70.7-0.8-0.70.7-0.60.1-0.30.00.2-0.3-1.50.1-0.1-1.21.8-1.8
Short access day 1 total infusions0.10.10.30.10.20.20.0-0.3-0.10.1-0.10.1-0.1-0.10.20.2-0.20.20.4-0.1-0.4-0.40.50.3-0.00.00.1-0.50.5
Short access day 10 total infusions0.70.82.31.00.90.80.90.7-0.9-0.60.6-0.60.60.6-0.7-0.50.5-0.51.4-1.0-1.5-1.41.4-0.20.7-0.7-0.5-0.80.8
Short access total infusions0.30.31.20.70.60.50.50.1-0.6-0.30.3-0.30.30.3-0.3-0.30.3-0.31.1-0.6-1.1-1.01.0-0.10.3-0.3-0.5-0.40.4
Short access day 1 locomotion0.10.10.50.10.30.30.0-0.5-0.1-0.20.2-0.20.20.20.10.0-0.00.00.10.1-0.0-0.10.1-0.6-0.20.2-0.60.7-0.7
Short access day 10 total locomotion0.70.75.80.20.40.40.0-0.0-0.2-0.50.5-0.50.50.5-0.3-0.30.3-0.3-0.20.10.30.4-0.6-1.7-0.40.4-1.22.4-2.4
Short access total locomotion0.40.52.60.40.70.60.3-0.1-0.5-0.50.5-0.50.50.5-0.3-0.40.4-0.40.4-0.2-0.3-0.20.1-1.4-0.10.1-1.11.6-1.6
One hour access (0.3 mA shock)0.20.21.00.50.50.50.50.1-0.5-0.30.3-0.30.30.3-0.5-0.20.2-0.20.9-0.5-1.0-0.80.8-0.00.3-0.3-0.5-0.50.5
Compulsive drug intake0.70.71.2-1.0-0.9-1.0-0.9-0.70.90.9-0.90.9-0.9-0.90.70.6-0.60.6-0.90.80.90.8-0.71.1-0.40.41.1-0.70.7
One hour access (shock baseline)0.10.10.50.30.30.40.3-0.2-0.3-0.10.1-0.10.10.1-0.10.2-0.20.20.7-0.3-0.7-0.60.7-0.0-0.10.1-0.5-0.30.3
Social response proportion0.20.20.80.40.40.40.40.5-0.4-0.10.1-0.10.10.1-0.4-0.50.5-0.50.8-0.4-0.9-0.60.6-0.00.5-0.5-0.1-0.50.5
Social responses6.88.711.43.23.33.13.23.1-3.1-2.92.9-2.92.92.9-3.3-3.43.4-3.43.3-3.0-3.4-2.82.8-3.02.9-2.9-2.21.0-0.9
Social time0.30.42.50.00.10.10.30.1-0.2-0.00.0-0.00.00.0-0.4-0.20.2-0.20.7-0.5-0.8-0.60.70.80.6-0.60.5-1.61.6
Soleus weight0.61.72.6-1.5-1.2-1.3-1.5-1.61.41.3-1.31.3-1.3-1.31.31.4-1.41.3-1.41.51.41.4-1.50.8-1.51.50.40.5-0.5
Bone: stiffness14.623.028.5-5.3-5.2-5.1-5.2-5.35.25.1-5.15.1-5.1-5.15.15.1-5.15.1-5.35.05.14.9-4.84.3-4.54.54.0-0.80.6
Tibialis anterior weight1.24.28.3-2.1-1.7-1.7-2.2-2.92.22.3-2.32.3-2.3-2.32.32.5-2.52.5-1.52.31.41.7-1.61.0-2.72.70.00.5-0.6
Time to tail flick, vehicle, before self-admin1.11.21.80.90.91.01.11.2-1.1-1.31.3-1.31.31.3-1.3-1.31.3-1.20.9-1.2-0.9-0.90.9-0.81.3-1.3-0.5-0.10.1
Time to tail flick, vehicle, after self-admin0.50.52.0-0.5-0.4-0.3-0.5-0.50.60.5-0.50.5-0.5-0.50.30.4-0.40.4-0.70.80.80.9-1.0-0.4-0.90.9-0.41.4-1.4
Time to tail flick, test, before self-admin0.40.41.10.70.70.70.71.0-0.6-0.70.7-0.70.70.7-0.5-0.60.6-0.60.6-0.6-0.5-0.50.5-0.50.6-0.6-0.4-0.00.0
Time to tail flick, test, after self-admin0.10.10.2-0.4-0.4-0.3-0.3-0.30.40.4-0.40.4-0.4-0.40.50.4-0.40.3-0.40.40.30.4-0.40.4-0.30.30.3-0.20.2
Delta time to tail flick, vehicle, before/after SA0.50.50.8-0.6-0.6-0.6-0.7-0.70.70.9-0.90.9-0.9-0.90.80.8-0.80.8-0.60.80.70.7-0.70.5-0.90.90.10.3-0.3
Delta time to tail flick, test, before/after SA0.20.20.7-0.5-0.5-0.5-0.5-0.80.40.4-0.40.4-0.4-0.40.50.4-0.40.3-0.40.50.40.4-0.40.4-0.40.40.10.0-0.0
Tibia length6.718.823.3-4.7-4.6-4.5-4.7-4.84.74.8-4.84.8-4.8-4.84.64.6-4.64.6-4.54.64.34.3-4.23.8-4.44.43.2-0.50.3
Ambulatory time before self-admin3.43.55.42.02.22.21.91.9-1.9-1.91.9-1.91.91.9-2.0-2.02.0-2.01.7-1.7-1.5-1.51.4-2.31.4-1.4-2.31.5-1.4
Ambulatory time after self-admin1.41.52.31.51.41.51.31.3-1.3-1.21.2-1.21.21.2-1.2-1.31.3-1.31.2-1.2-1.1-1.11.1-1.41.0-1.0-1.50.9-0.9
Bone: tissue strength0.80.82.0-1.1-1.0-0.8-0.7-0.80.90.8-0.80.8-0.8-0.80.70.7-0.70.7-1.30.91.41.2-1.30.5-0.80.80.90.4-0.4
Total heroin consumption2.32.74.1-1.7-1.4-1.5-1.8-1.91.71.5-1.51.5-1.5-1.51.61.6-1.61.6-1.71.91.72.0-2.00.1-2.02.00.61.5-1.6
Bone: trabecular number5.28.216.4-3.1-3.2-3.2-2.9-2.82.92.9-2.92.9-2.9-2.92.92.9-2.92.9-3.02.42.82.3-2.24.0-1.71.73.5-2.62.5
Bone: trabecular spacing2.02.66.71.81.81.71.51.6-1.5-1.61.6-1.61.61.6-1.6-1.61.6-1.61.6-1.1-1.5-1.00.9-2.60.7-0.7-2.12.1-2.0
Bone: trabecular thickness0.30.31.50.30.40.20.3-0.0-0.4-0.30.3-0.30.30.3-0.3-0.30.3-0.30.5-0.6-0.5-0.80.80.80.7-0.70.4-1.21.2
Bone: trabecular tissue density0.20.21.70.30.10.30.10.2-0.2-0.40.4-0.40.40.4-0.3-0.30.3-0.3-0.0-0.00.10.2-0.3-0.6-0.10.1-0.71.3-1.3
Water consumed over 24 hours0.00.00.2-0.1-0.2-0.2-0.2-0.20.00.0-0.00.0-0.0-0.0-0.0-0.10.1-0.1-0.1-0.10.1-0.00.00.40.3-0.3-0.3-0.40.4
Number of responses in last shaping day0.30.31.2-0.4-0.00.0-0.3-1.10.40.4-0.40.4-0.4-0.40.40.5-0.50.5-0.30.50.40.4-0.4-0.2-0.70.7-0.40.9-0.9