Best TWAS P=8.045289e-08 · Best GWAS P=8.045289e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Tcea3 | mRNA stability | ENSRNOG00000011794 | 0.12 | 0.17 | top1 | 1 | 0.17 | 6.1e-16 | 5.3 | 5.3 | 1.5e-07 | 0.96 | 0.08 | 0.92 | FALSE |
| 2 | Liver | Tcea3 | gene expression | ENSRNOG00000011794 | 0.13 | 0.08 | enet | 58 | 0.09 | 5.4e-10 | 4.9 | 5.1 | 3.2e-07 | 0.93 | 0.41 | 0.59 | FALSE |
| 3 | NAcc | Asap3 | gene expression | ENSRNOG00000049714 | 0.07 | 0.06 | top1 | 1 | 0.06 | 2.5e-05 | 5.4 | -5.4 | 8.0e-08 | -0.95 | 0.04 | 0.89 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.