Hub : Traits : body_g :

chr6:96,850,756-98,633,235

Best TWAS P=1.479845e-08 · Best GWAS P=2.332971e-08 conditioned to 0.2042008

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 Adipose Pigh gene expression ENSRNOG00000010914 0.11 0.02 enet 17 0.07 3.4e-08 4.5 5.6 2.4e-08 -0.75 0.49 0.51 FALSE
2 BLA Pigh alternative polyA ENSRNOT00000014775 0.12 0.04 enet 30 0.06 5.1e-04 -5.3 -5.5 5.0e-08 0.81 0.30 0.62 FALSE
3 BLA Pigh alternative polyA ENSRNOT00000101349 0.16 0.05 blup 2175 0.07 8.8e-05 -5.3 5.3 1.5e-07 -0.77 0.29 0.69 FALSE
4 BLA Pigh gene expression ENSRNOG00000010914 0.25 0.14 enet 114 0.20 5.3e-11 -5.3 5.5 3.2e-08 -0.93 0.09 0.91 FALSE
5 BLA Arg2 gene expression ENSRNOG00000053811 0.20 0.17 top1 1 0.17 2.4e-09 -5.3 5.3 1.5e-07 -0.92 0.11 0.88 FALSE
6 BLA Pigh isoform ratio ENSRNOT00000014775 0.19 0.09 enet 119 0.13 2.8e-07 -5.3 -5.4 7.5e-08 0.84 0.25 0.75 FALSE
7 BLA Pigh isoform ratio ENSRNOT00000101349 0.18 0.10 enet 156 0.11 1.0e-06 -5.3 5.6 1.8e-08 -0.89 0.14 0.86 FALSE
8 BLA Arg2 mRNA stability ENSRNOG00000053811 0.15 0.12 top1 1 0.12 5.8e-07 -5.3 5.3 1.0e-07 -0.97 0.08 0.86 FALSE
9 Brain Atp6v1d mRNA stability ENSRNOG00000009080 0.09 0.01 blup 1744 0.04 3.0e-04 -5.5 -5.5 4.6e-08 0.94 0.04 0.94 FALSE
10 IL Mpp5 mRNA stability ENSRNOG00000008788 0.65 0.23 blup 1508 0.29 1.2e-07 -4.8 5.2 2.0e-07 -0.91 0.04 0.96 FALSE
11 Liver Pigh isoform ratio ENSRNOT00000101349 0.03 0.00 blup 2174 0.00 9.9e-02 -5.0 5.7 1.5e-08 -0.88 0.19 0.57 TRUE
12 NAcc Mpp5 mRNA stability ENSRNOG00000008788 0.36 0.12 enet 9 0.12 1.1e-03 -5.3 5.5 3.9e-08 -0.90 0.06 0.82 FALSE
13 NAcc2 Pigh intron excision ratio chr6:97889566:97890560 0.10 0.07 top1 1 0.07 1.7e-04 -5.3 -5.3 9.5e-08 0.88 0.08 0.31 FALSE
14 OFC Pigh gene expression ENSRNOG00000010914 0.28 0.10 lasso 15 0.11 1.3e-03 -4.8 5.1 2.7e-07 -0.94 0.14 0.71 FALSE
15 PL Pigh gene expression ENSRNOG00000010914 0.54 0.36 top1 1 0.36 1.8e-09 -5.5 5.5 3.7e-08 -0.91 0.03 0.96 FALSE
16 PL2 Pigh gene expression ENSRNOG00000010914 0.45 0.17 blup 2175 0.24 2.6e-13 -4.8 5.4 5.9e-08 -0.85 0.10 0.90 FALSE
17 PL2 Pigh isoform ratio ENSRNOT00000101349 0.08 0.03 blup 2175 0.05 1.3e-03 -5.3 5.2 2.1e-07 -0.91 0.14 0.79 FALSE
18 PL2 Mpp5 mRNA stability ENSRNOG00000008788 0.67 0.38 enet 105 0.41 1.3e-23 -5.0 5.2 2.3e-07 -0.87 0.10 0.90 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.