Hub : Traits : body_g : ← →

chr2:117,887,529-120,258,488

Best TWAS P=3.740398e-08 · Best GWAS P=3.098109e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Qrfpr	gene expression	ENSRNOG00000014414	0.20	0.09	top1	1	0.10	1.2e-10	5.5	-5.5	3.7e-08	-0.98	0.19	0.81	TRUE
2	Adipose	NA	gene expression	ENSRNOG00000066024	0.04	0.02	top1	1	0.02	9.6e-04	5.4	5.4	5.5e-08	0.94	0.07	0.06	FALSE
3	Adipose	Atp11b	mRNA stability	ENSRNOG00000052116	0.13	0.06	blup	1833	0.06	1.8e-07	5.0	5.2	2.5e-07	0.96	0.36	0.64	FALSE
4	BLA	Qrfpr	gene expression	ENSRNOG00000014414	0.36	0.21	top1	1	0.21	2.9e-11	5.3	5.3	1.1e-07	0.98	0.39	0.61	FALSE
5	Brain	Qrfpr	gene expression	ENSRNOG00000014414	0.67	0.63	enet	239	0.64	1.0e-77	5.4	5.4	6.4e-08	0.99	0.41	0.59	FALSE
6	Brain	Trpc3	intron excision ratio	chr2:119485307:119499985	0.11	0.08	blup	2047	0.09	1.8e-08	5.0	-5.1	3.3e-07	-0.94	0.66	0.34	FALSE
7	Brain	Qrfpr	mRNA stability	ENSRNOG00000014414	0.39	0.28	lasso	32	0.32	5.6e-30	5.3	5.5	4.7e-08	0.81	0.41	0.59	FALSE
8	Liver	Dcun1d1	alternative polyA	ENSRNOT00000068334	0.03	0.00	blup	2146	0.01	6.0e-02	5.4	-5.3	1.3e-07	-0.98	0.27	0.28	FALSE
9	Liver	Dcun1d1	gene expression	ENSRNOG00000012734	0.10	0.06	top1	1	0.06	3.0e-07	5.4	-5.4	5.5e-08	-0.96	0.24	0.74	FALSE
10	Liver	Anxa5	intron excision ratio	chr2:119326053:119327400	0.03	0.00	lasso	9	0.01	2.3e-02	5.3	5.1	2.7e-07	0.90	0.42	0.27	FALSE
11	NAcc	Acad9	alternative polyA	ENSRNOT00000113867	0.39	0.08	blup	2231	0.08	7.1e-03	5.4	5.4	6.9e-08	0.98	0.34	0.41	FALSE
12	OFC	Qrfpr	gene expression	ENSRNOG00000014414	0.85	0.41	top1	1	0.41	5.7e-11	5.4	5.4	5.5e-08	0.97	0.25	0.74	FALSE
13	PL	Qrfpr	gene expression	ENSRNOG00000014414	0.75	0.39	top1	1	0.39	3.3e-10	5.4	5.4	6.4e-08	0.97	0.27	0.68	FALSE
14	PL2	Qrfpr	gene expression	ENSRNOG00000014414	0.57	0.41	enet	178	0.42	1.7e-24	5.3	5.5	4.6e-08	0.37	0.44	0.56	TRUE
15	PL2	Bbs7	gene expression	ENSRNOG00000015816	0.12	0.05	top1	1	0.05	7.8e-04	5.3	-5.3	9.8e-08	-0.95	0.09	0.07	FALSE
16	PL2	Qrfpr	mRNA stability	ENSRNOG00000014414	0.21	0.09	enet	25	0.13	1.1e-07	5.3	5.4	5.7e-08	0.87	0.43	0.57	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.