Hub : Genes

LOC120095201

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC120095201 0.05 0.03 1.2e-08 0.04 0.06 0.05 0.05 2.9e-07 8.2e-09 1.5e-08 6.5e-08
2 OFC gene expression LOC120095201 0.19 0.1 8.0e-04 0.12 0.15 0.14 0.12 1.1e-03 2.5e-04 4.4e-04 1.1e-03
3 IL gene expression LOC120095201 0.19 0.11 1.9e-03 0.01 0.06 0.06 0.01 1.9e-01 1.5e-02 1.9e-02 1.5e-01
4 PL gene expression LOC120095201 0.11 0.05 1.8e-11 0.09 0.1 0.1 0.09 2.9e-10 6.2e-11 1.2e-10 2.9e-10
5 Brain gene expression LOC120095201 0.07 0.04 3.5e-08 0.07 0.09 0.06 0.09 6.0e-07 8.6e-09 5.5e-06 5.6e-09
6 pVTA gene expression LOC120095201 0.06 0.03 1.3e-05 0.03 0.06 0.04 0.04 1.6e-03 9.9e-06 2.6e-04 4.2e-04
7 IC gene expression LOC120095201 0.11 0.07 3.1e-04 0.11 0.07 0.07 0.08 2.9e-05 5.0e-04 6.4e-04 2.9e-04
8 LHb gene expression LOC120095201 0.26 0.12 2.3e-04 0.1 0.15 0.07 0.09 2.2e-03 2.5e-04 1.1e-02 3.7e-03
9 BLA gene expression LOC120095201 0.05 0.03 9.7e-03 0.04 0.03 -0 0.03 3.8e-03 1.7e-02 4.9e-01 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.95.09.9-1.7-1.9-1.5-2.1-1.8-2.1-3.0-2.2-3.2
Area under the delay curve0.10.10.40.20.10.30.40.60.30.40.30.3
BMI with tail7.626.128.55.25.34.95.24.55.35.25.35.1
BMI without tail11.735.739.26.16.25.66.25.26.06.36.06.1
Body weight12.052.557.07.57.57.67.57.27.56.77.46.4
Weight adjusted by age2.84.36.21.81.91.82.11.52.22.42.32.5
Bone surface2.03.69.9-1.2-1.5-0.8-1.5-0.8-1.7-2.9-1.9-3.1
Bone volume1.32.37.3-0.7-1.1-0.4-1.1-0.4-1.4-2.4-1.5-2.7
Breakpoint value in progressive ratio session0.10.20.60.30.40.00.3-0.30.30.70.40.6
Number of licking bursts0.20.30.50.50.60.70.60.70.70.40.70.1
Context. condit. distance diff. score0.20.20.40.50.40.50.40.60.40.20.40.5
Locomotion velocity, session 10.00.00.10.20.2-0.00.2-0.0-0.00.4-0.10.0
Locomotion distance, session 10.00.00.20.40.30.00.2-0.1-0.00.3-0.10.1
Locomotion velocity, session 20.50.61.3-0.5-0.6-1.0-0.7-0.9-1.0-0.4-1.1-0.5
Locomotion distance, session 20.30.40.8-0.3-0.3-0.8-0.5-0.9-0.8-0.3-0.9-0.3
Locomotion velocity, session 30.30.41.30.60.7-0.10.5-0.30.21.20.10.9
Locomotion distance, session 30.00.00.10.0-0.0-0.00.0-0.1-0.10.0-0.2-0.3
Stereotopy head waving bouts, day 33.33.96.5-2.2-2.1-2.6-2.1-2.4-2.0-0.8-1.9-0.8
Stereotopy head waving duration, day 32.12.54.0-1.7-1.6-2.0-1.6-1.8-1.7-0.8-1.6-0.7
Locomotion velocity, session 70.20.20.3-0.3-0.3-0.4-0.4-0.6-0.4-0.4-0.4-0.5
Locomotion distance, session 70.10.10.30.40.20.40.20.50.0-0.5-0.1-0.3
Stereotopy head waving bouts, day 71.51.73.7-1.4-1.2-1.5-1.4-1.9-1.2-0.9-1.1-1.1
Stereotopy head waving duration, day 72.93.56.4-2.0-1.8-2.1-2.0-2.5-1.8-1.3-1.6-1.5
Locomotion velocity, session 80.00.00.1-0.0-0.1-0.10.00.2-0.10.3-0.10.4
Locomotion distance, session 80.00.10.10.40.2-0.10.20.1-0.20.2-0.30.3
Degree of sensitization distance0.00.00.20.20.00.10.00.5-0.1-0.3-0.10.1
Degree of sensitization stereotypy0.20.21.1-0.4-0.2-0.5-0.4-1.0-0.3-0.2-0.2-0.5
Conditioned locomotion0.30.40.6-0.5-0.6-0.6-0.6-0.5-0.7-0.6-0.8-0.7
Cocaine response after cond. corrected0.00.10.2-0.0-0.10.30.00.50.1-0.30.1-0.3
Cocaine response after cond. not corrected0.10.10.30.0-0.00.40.10.60.1-0.30.1-0.4
Cocaine response before conditioning0.00.00.1-0.1-0.1-0.2-0.1-0.1-0.20.0-0.2-0.1
Saline control response4.86.47.82.62.72.22.61.92.52.82.52.8
Bone: connectivity density6.09.313.3-2.6-2.7-2.6-3.0-3.0-3.1-3.6-3.1-3.6
Bone: cortical apparent density0.40.61.3-0.8-0.7-1.1-0.6-1.1-0.50.6-0.40.6
Bone: cortical area0.40.61.31.10.90.80.90.80.50.80.30.4
Bone: cortical porosity0.30.30.70.70.50.70.50.80.2-0.4-0.0-0.5
Bone: cortical porosity1.31.42.51.51.31.51.31.61.00.40.80.4
Bone: cortical thickness1.01.75.91.01.20.21.0-0.20.82.40.92.1
Bone: cortical thickness0.50.51.9-0.5-0.4-1.1-0.6-1.4-0.70.3-0.70.0
Bone: cortical tissue density0.40.61.3-0.8-0.6-1.1-0.6-1.1-0.50.6-0.40.6
Condit. Reinf. active minus inactive responses1.71.93.31.61.41.61.61.81.21.11.00.8
Condit. Reinf. active-inactive response ratio0.10.10.40.30.20.50.40.60.40.00.3-0.2
Condit. Reinf. active responses1.11.32.51.51.31.31.31.60.90.80.60.6
Condit. Reinf. inactive responses0.10.10.50.70.50.30.40.4-0.00.1-0.20.1
Incentive salience index mean0.81.01.41.21.11.11.11.20.90.70.70.6
Condit. Reinf. lever presses0.20.30.60.60.80.50.60.20.60.50.60.5
Condit. Reinf. active minus inactive responses0.30.30.80.70.40.70.50.9-0.1-0.5-0.3-0.7
Condit. Reinf. active-inactive response ratio0.30.30.80.40.20.60.20.8-0.0-0.8-0.2-0.9
Condit. Reinf. active responses0.40.51.31.10.70.90.71.10.1-0.3-0.2-0.5
Condit. Reinf. inactive responses0.10.10.40.70.40.10.40.3-0.20.3-0.40.2
Condit. Reinf. lever presses0.71.01.91.41.21.21.11.30.70.40.60.4
Condit. Reinf. lever reinforcers received0.40.61.41.10.71.00.81.20.2-0.3-0.1-0.5
Conditioned reinforcement - actives0.40.71.3-0.7-0.7-0.6-0.8-0.6-0.8-1.0-0.9-1.1
Conditioned reinforcement - inactives0.20.30.50.60.60.70.50.60.60.20.50.2
Conditioned locomotion1.01.32.21.31.11.51.21.31.10.71.00.6
Patch foraging indifference point 0 sec3.25.98.93.02.72.32.72.52.02.31.82.4
Patch foraging indifference point AUC1.01.42.21.21.11.11.31.21.11.51.01.1
Delay disc. indifference point, 0s delay0.00.00.1-0.3-0.30.0-0.10.10.0-0.40.1-0.2
Delay disc. indifference point, 16s delay0.91.01.60.80.80.91.01.30.91.00.91.0
Delay disc. indifference point, 2s delay0.00.00.1-0.2-0.4-0.10.0-0.1-0.2-0.2-0.3-0.2
Delay disc. indifference point, 24s delay0.40.41.20.80.70.90.61.10.60.20.50.1
Delay disc. indifference point, 4s delay0.00.00.1-0.2-0.3-0.10.00.1-0.10.2-0.10.0
Delay disc. indifference point, 8s delay0.00.00.2-0.1-0.0-0.10.1-0.00.20.50.20.2
Indifference point function ln k1.32.33.6-1.1-1.2-1.7-1.5-1.7-1.8-1.4-1.9-1.1
Indifference point function log k1.32.33.6-1.1-1.2-1.7-1.5-1.7-1.8-1.4-1.9-1.1
Patch foraging total patch changes 0 sec3.05.78.32.92.72.22.62.42.02.31.72.5
Patch foraging total patch changes 12 sec2.12.84.02.01.71.81.92.01.51.51.31.3
Patch foraging total patch changes 18 sec3.24.96.42.52.42.02.41.92.02.51.82.4
Patch foraging total patch changes 24 sec1.42.44.42.11.81.61.81.61.31.41.01.2
Patch foraging total patch changes 6 sec6.610.113.53.73.33.33.53.42.93.02.62.7
Patch foraging time to switch 0 sec0.10.10.50.00.10.50.20.40.60.10.70.0
Patch foraging water rate 0 sec0.51.01.81.31.10.91.21.00.61.10.51.2
Patch foraging water rate 12 sec0.51.11.71.21.20.81.10.50.91.30.81.3
Patch foraging water rate 18 sec0.30.51.0-0.4-0.4-0.8-0.8-1.0-0.8-0.7-0.8-0.6
Patch foraging water rate 24 sec0.60.81.2-0.7-0.7-1.0-0.9-1.1-1.0-0.8-1.1-0.7
Patch foraging water rate 6 sec0.10.20.6-0.2-0.3-0.6-0.3-0.8-0.50.1-0.50.1
Seeking ratio, delayed vs. immediate footshock2.43.03.41.61.51.71.81.91.71.81.71.7
Distance traveled before self-admin0.10.10.3-0.1-0.1-0.20.2-0.20.00.50.00.5
Distance traveled after self-admin0.10.10.60.30.10.30.50.10.20.80.20.4
Extensor digitorum longus weight1.45.610.51.82.32.32.11.63.02.33.22.2
Bone: elastic displacement0.30.41.3-0.3-0.2-0.8-0.5-1.1-0.6-0.1-0.6-0.2
Bone: elastic work0.30.30.90.80.90.40.6-0.00.50.60.50.2
Bone: endosteal estimation1.02.37.41.30.62.21.12.70.7-1.20.4-1.7
Bone: endosteal perimeter1.12.26.91.40.72.21.12.60.6-1.30.2-1.7
Epididymis fat weight6.321.728.24.24.64.74.54.45.14.55.34.3
Delta time in closed arm before/after self-admin2.12.03.5-1.5-1.5-1.1-1.5-1.0-1.3-1.9-1.2-1.4
Delta time in open arm before/after self-admin0.70.71.1-0.7-0.7-1.1-0.9-1.0-0.9-0.5-1.0-0.6
Diff in mean of infusions in LGA sessions0.40.40.80.40.60.40.50.10.80.90.90.9
Delay discount exponential model param0.20.20.6-0.3-0.2-0.5-0.5-0.8-0.3-0.4-0.3-0.3
Extinction: sum of active levers before priming0.91.01.31.00.91.11.01.11.11.01.10.7
Active lever presses in extinction session 60.00.00.10.10.00.1-0.0-0.30.00.00.0-0.1
Bone: final force0.10.10.40.0-0.20.1-0.00.2-0.2-0.4-0.3-0.6
Bone: final moment0.10.10.6-0.1-0.3-0.0-0.10.0-0.4-0.4-0.5-0.8
Food consumed during 24 hour testing period2.43.36.31.71.81.31.81.11.72.51.82.3
Glucose0.10.10.30.30.40.40.30.20.50.20.50.3
Heart weight1.32.03.01.71.61.71.51.31.40.91.40.7
Delay discount hyperbolic model param0.10.10.5-0.3-0.1-0.4-0.4-0.7-0.3-0.4-0.3-0.2
Intermittent access intake day 1-15 change0.61.22.70.90.91.50.91.61.30.51.30.5
Intermittent access intake escalation0.91.83.21.11.21.61.21.81.50.91.50.8
Intermittent access intake escalation 20.70.82.20.70.71.30.71.51.00.21.00.1
Intermitt. access day 1 inactive lever presses0.51.83.01.41.41.61.21.71.40.81.41.0
Intermitt. access day 15 inactive lever presses1.02.13.31.11.31.61.31.61.71.21.81.3
Intermitt. access escalation Index0.00.00.1-0.1-0.1-0.20.1-0.0-0.00.30.00.2
Intermittent access day 1 total infusions0.10.20.40.60.60.20.50.30.20.40.10.5
Intermittent access day 15 total infusions1.72.53.51.61.71.81.61.91.71.21.61.3
Intermittent access terminal intake (last 3 days)1.11.42.81.21.21.61.21.71.30.61.10.6
Intermittent access total infusions0.50.61.00.90.90.90.81.00.70.40.60.4
Intermittent access day 1 locomotion2.63.34.32.02.11.91.82.11.81.41.71.6
Intermittent access day 15 total locomotion1.01.73.01.61.51.61.31.71.20.61.10.7
Intermittent access total locomotion4.45.37.32.72.62.52.32.72.21.72.01.8
Intermittent access standard deviation0.91.83.21.11.21.81.21.71.60.71.50.7
Left kidney weight0.52.53.21.71.81.51.61.51.61.41.51.5
Right kidney weight0.73.23.81.81.91.91.81.81.91.42.01.5
Cocaine induced anxiety1.31.82.7-1.3-1.4-1.0-1.3-0.9-1.3-1.6-1.3-1.6
Post-drug Anxiety1.51.62.1-1.3-1.4-1.2-1.3-1.2-1.3-1.2-1.3-1.3
Baseline Anxiety0.20.20.7-0.1-0.0-0.30.2-0.30.10.80.20.8
Tail length2.710.412.33.43.43.33.53.23.23.03.02.9
Length with tail3.213.917.43.83.84.23.94.23.92.93.82.8
Length without tail1.44.56.72.02.02.62.12.42.41.42.51.2
Times rat made contact with spout0.80.91.21.01.10.91.00.81.00.91.00.8
Lifetime Intake0.50.61.11.01.10.80.90.90.70.60.60.7
Liver weight, left0.30.51.20.90.70.90.71.10.4-0.00.30.1
Liver weight, right0.61.11.70.91.10.80.90.71.11.31.11.2
Locomotor activity1.32.03.31.81.81.41.51.11.21.31.11.2
Locomotor testing distance1.52.74.22.02.01.61.81.31.41.71.31.5
Locomotor testing rearing2.44.86.52.52.52.02.41.62.02.61.92.1
Locomotion in novel chamber0.10.10.3-0.3-0.2-0.1-0.0-0.20.10.40.20.6
Locomotion in novel chamber post-restriction0.00.00.1-0.3-0.2-0.3-0.3-0.1-0.2-0.2-0.2-0.0
Fecal boli incidents, locomotor time 10.10.20.7-0.3-0.40.1-0.40.4-0.2-0.8-0.2-0.6
Change in fecal boli incidents, locomotor task0.10.10.3-0.5-0.5-0.4-0.1-0.5-0.20.3-0.2-0.1
Time >=10cm from walls, locomotor time 10.70.71.6-0.8-0.7-1.1-0.9-1.3-0.9-0.5-0.9-0.4
Bouts of movement, locomotor time 11.01.11.41.01.11.11.01.01.11.01.21.0
Total resting periods, locomotor time 10.50.50.90.60.70.80.60.80.90.50.90.5
Rest time, locomotor task time 10.20.20.5-0.7-0.5-0.2-0.5-0.3-0.1-0.7-0.0-0.6
Distance moved, locomotor task time 10.60.92.20.80.90.50.90.30.81.50.81.2
Vertical activity count, locomotor time 10.30.61.80.70.70.40.70.50.61.30.61.1
Time >=10cm from walls, locomotor time 20.81.12.70.70.90.50.90.11.11.61.21.6
Bouts of movement, locomotor time 22.53.95.62.02.11.71.91.32.02.22.12.4
Total resting periods, locomotor time 21.83.14.21.81.91.51.71.21.81.91.82.0
Rest time, locomotor task time 23.03.85.0-2.2-2.2-1.8-2.1-1.7-1.8-1.9-1.6-2.0
Distance moved, locomotor task time 21.82.14.01.21.40.91.30.61.52.01.62.0
Vertical activity count, locomotor time 22.12.84.01.71.81.41.61.21.72.01.72.0
Light reinforcement 10.30.71.61.01.00.30.8-0.10.51.30.51.0
Light reinforcement 20.00.10.20.30.40.20.30.10.30.20.30.1
Bone: marrow area1.02.27.01.20.62.11.02.60.7-1.20.3-1.7
Bone: maximum diameter0.30.62.60.1-0.30.4-0.10.7-0.5-1.2-0.8-1.6
Bone: maximum force0.10.20.50.50.30.70.40.70.1-0.4-0.1-0.7
Bone: maximum moment0.10.20.60.50.20.60.30.6-0.0-0.4-0.2-0.8
Mean time between licks in bursts1.02.43.61.51.61.91.51.71.80.91.91.0
Mean num. licks in bursts0.00.00.10.10.1-0.2-0.0-0.2-0.10.1-0.10.4
Cd content in liver1.11.22.0-1.4-1.3-0.9-1.3-1.0-0.8-1.1-0.6-1.3
Co content in liver0.00.00.2-0.10.00.2-0.0-0.10.3-0.10.40.0
Cu content in liver0.00.00.1-0.1-0.10.0-0.00.2-0.1-0.1-0.1-0.3
Fe content in liver0.10.10.3-0.1-0.2-0.2-0.2-0.1-0.5-0.4-0.6-0.5
K content in liver1.21.21.5-1.0-1.0-1.1-1.0-1.0-1.2-1.0-1.2-1.1
Mg content in liver4.34.44.9-2.1-2.1-2.1-2.1-2.2-2.1-1.9-2.1-2.0
Mn content in liver4.85.36.4-2.2-2.2-2.4-2.3-2.5-2.5-2.0-2.5-2.1
Na content in liver0.91.01.1-1.0-1.0-1.0-0.9-1.0-1.0-0.8-1.0-1.0
Rb content in liver1.21.41.9-1.4-1.3-1.4-1.2-1.1-1.2-0.8-1.2-0.9
Se content in liver0.30.30.8-0.5-0.4-0.8-0.5-0.9-0.7-0.2-0.7-0.2
Sr content in liver1.41.21.41.21.11.11.11.11.11.01.11.1
Zn content in liver0.60.60.8-0.7-0.7-0.7-0.8-0.5-0.9-0.9-0.9-0.9
Bone: minimum diameter1.52.87.92.01.52.41.72.81.2-0.20.8-0.5
Time in familiar zone, hab. session 10.30.31.10.50.30.80.51.00.50.00.40.0
Time in novel zone, hab. session 10.20.20.5-0.3-0.2-0.6-0.3-0.7-0.4-0.0-0.40.1
Total zone transitions, hab. session 11.01.32.11.31.41.11.10.81.11.11.11.2
Total locomotion distance, hab. session 10.71.02.21.11.20.71.10.50.81.50.81.2
Locomotion velocity, hab. session 10.71.01.91.01.10.71.00.50.81.40.81.2
Time in familiar zone, hab. session 20.50.50.90.90.60.90.81.00.60.50.50.2
Time in novel zone, hab. session 22.22.23.1-1.6-1.4-1.8-1.6-1.7-1.5-1.2-1.4-1.0
Total zone transitions, hab. session 21.11.42.21.31.50.91.10.71.11.11.11.4
Total locomotion distance, hab. session 21.21.53.51.21.30.71.10.51.11.91.11.7
Locomotion velocity, hab. session 20.71.02.70.91.00.40.80.20.81.60.81.5
Novel to familiar place preference ratio0.91.01.91.21.01.41.11.40.90.50.80.2
Novelty place preference0.60.61.31.00.81.10.91.00.70.30.70.1
Time in novel zone, NPP test0.40.50.90.90.71.00.80.90.60.20.50.0
Total zone transitions, NPP test0.20.20.70.60.6-0.10.3-0.1-0.00.8-0.10.8
Total locomotion distance, NPP test0.20.31.10.30.4-0.40.2-0.3-0.11.1-0.20.9
Locomotion velocity, NPP test0.50.72.40.80.90.10.70.10.41.50.41.3
Intraocular pressure1.01.42.31.51.31.11.31.20.91.10.81.1
Delta distance traveled before/after self-admin0.10.10.30.50.40.30.40.10.20.60.10.3
Delta ambulatory time before/after self-admin0.00.00.20.2-0.00.20.10.1-0.1-0.0-0.1-0.4
Parametrial fat weight0.92.02.9-1.7-1.7-1.3-1.5-1.1-1.2-1.4-1.2-1.5
Pavlov. Cond. lever latency3.74.76.1-2.3-2.5-2.2-2.3-1.9-2.2-1.9-2.2-2.1
Pavlov. Cond. magazine entry latency0.81.01.41.11.01.21.11.21.00.60.90.7
Pavlov. Cond. change in total contacts2.52.63.41.81.81.81.81.71.71.11.61.2
Pavlov. Cond. index score2.02.53.01.71.71.71.71.61.61.21.61.3
Pavlov. Cond. latency score2.73.44.12.02.02.02.01.81.91.41.91.6
Pavlov. Cond. lever contacts3.13.74.72.02.22.02.01.72.01.62.11.7
Pavlov. Cond. magazine entry number0.60.71.2-0.9-0.8-1.1-0.9-1.1-0.9-0.4-0.9-0.6
Pavlov. Cond. intertrial magazine entries1.92.33.82.01.61.71.81.81.21.20.91.1
Pavlov. Cond. lever-magazine prob. diff.1.51.82.31.51.51.51.51.41.30.91.31.1
Pavlov. Cond. response bias0.60.81.00.91.01.00.91.00.90.50.80.7
Pavlov. Cond. lever latency0.20.20.60.00.20.20.30.10.60.70.80.8
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.2-0.1-0.1-0.1-0.10.2-0.1-0.1
Pavlov. Cond. change in total contacts0.10.20.60.1-0.2-0.1-0.1-0.1-0.5-0.4-0.6-0.8
Pavlov. Cond. index score0.10.10.50.1-0.10.0-0.10.1-0.3-0.4-0.5-0.7
Pavlov. Cond. latency score0.10.10.40.1-0.2-0.1-0.10.0-0.4-0.3-0.5-0.6
Pavlov. Cond. lever contacts0.20.20.6-0.0-0.2-0.3-0.3-0.2-0.6-0.6-0.8-0.7
Pavlov. Cond. magazine entry number0.00.00.10.10.10.10.00.20.1-0.30.1-0.0
Pavlov. Cond. intertrial magazine entries0.00.10.20.20.20.30.10.50.0-0.3-0.00.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.0-0.2-0.0-0.10.0-0.4-0.4-0.5-0.7
Pavlov. Cond. response bias0.20.30.7-0.2-0.3-0.3-0.4-0.3-0.7-0.7-0.8-0.8
Time in closed arm before self-admin2.02.54.71.61.71.11.71.31.32.01.32.2
Time in closed arm after self-admin1.01.02.00.80.90.81.00.91.11.11.11.4
Time in open arm before self-admin1.01.12.00.80.91.20.90.91.30.81.40.7
Time in open arm after self-admin0.10.10.10.40.30.40.30.30.30.20.30.0
Bone: periosteal estimation0.71.54.91.40.81.81.22.20.6-0.50.2-1.1
Bone: periosteal perimeter0.71.33.71.30.81.71.11.90.7-0.40.4-0.8
Bone: post-yield work0.50.81.90.90.81.40.81.40.8-0.30.7-0.4
Progressive ratio test 1 active lever presses3.23.95.12.12.31.82.11.81.91.91.82.1
Progressive ratio test 1 breakpoint2.93.64.72.02.21.72.01.71.81.81.72.0
Progressive ratio test 1 inactive lever presses3.44.96.02.32.42.32.32.32.22.02.12.1
Progressive ratio test 2 active lever presses0.60.70.90.91.00.81.00.70.80.90.70.8
Progressive ratio test 2 breakpoint0.70.81.00.91.00.81.00.70.91.00.80.8
Progressive ratio test 2 inactive lever presses0.40.71.00.81.00.80.80.70.90.80.90.8
Incentive Sensitization - Responses0.00.00.10.1-0.00.10.30.10.10.30.00.1
Incentive Sensitization - Breakpoint0.00.00.1-0.0-0.10.00.20.00.00.2-0.00.0
Sum of active levers in priming session hrs 5-60.30.31.00.30.40.30.40.20.51.00.50.5
Progressive ratio0.00.00.1-0.1-0.20.1-0.00.20.0-0.10.0-0.3
Food seeking constrained by brief footshock0.10.10.7-0.2-0.20.0-0.30.2-0.2-0.9-0.2-0.5
Seeking ratio, punishment vs. effort0.00.10.20.40.40.20.20.20.10.00.10.4
Retroperitoneal fat weight3.113.317.63.43.73.73.53.34.13.44.23.3
Reaction time number correct0.91.82.2-1.2-1.2-1.3-1.2-1.5-1.4-1.4-1.4-1.3
Reaction time mean minus median0.00.10.5-0.20.00.30.10.20.60.10.70.1
Reaction time mean minus median AUC0.40.91.2-1.1-1.0-0.9-1.0-0.8-0.8-1.1-0.8-1.0
Reaction time num false alarms1.41.93.51.91.61.61.61.61.01.00.81.0
Reaction time num false alarms AUC0.81.32.51.61.31.31.31.40.80.70.60.7
Reaction time trials correct on left0.91.82.2-1.2-1.2-1.3-1.2-1.5-1.4-1.4-1.4-1.3
Reaction time trials on left1.01.82.2-1.2-1.2-1.3-1.3-1.5-1.4-1.5-1.4-1.4
Reaction time mean0.61.02.0-1.4-1.3-1.0-1.1-0.7-0.8-0.9-0.7-0.8
Reaction time mean AUC0.60.91.9-1.4-1.2-1.0-1.1-0.7-0.8-0.8-0.7-0.7
Median of all reaction times1.31.82.8-1.7-1.6-1.4-1.5-1.0-1.2-1.2-1.2-1.0
Reaction time omissions0.20.20.6-0.6-0.5-0.2-0.6-0.1-0.3-0.8-0.2-0.6
Reaction time false alarm rate1.92.74.01.91.71.81.82.01.41.31.21.4
Reaction time premature initiation rate2.23.04.01.91.71.91.92.01.61.71.51.4
Reaction time premature initiations0.20.40.80.90.60.80.80.80.50.50.30.2
Std. dev. reaction times0.40.71.5-1.2-1.0-0.7-1.0-0.6-0.5-0.9-0.4-0.8
Reaction time trials completed1.01.82.2-1.2-1.2-1.3-1.3-1.5-1.4-1.5-1.4-1.4
Reaction time trials AUC1.01.82.2-1.2-1.3-1.3-1.3-1.5-1.4-1.4-1.4-1.3
Run reversals in cocaine runway, females5.15.17.91.82.02.22.11.82.62.32.82.5
Run reversals in cocaine runway, males0.10.10.3-0.5-0.6-0.3-0.3-0.1-0.3-0.1-0.2-0.1
Latency to leave start box in cocaine runway0.60.62.70.50.5-0.20.6-0.20.41.40.41.6
Latency to leave start box in cocaine runway, F1.92.26.11.31.30.71.50.61.22.01.22.5
Latency to leave start box in cocaine runway, M0.40.41.1-0.7-0.6-1.1-0.5-0.8-0.60.1-0.60.0
Std. dev. time between licks in bursts0.10.10.30.00.20.00.1-0.30.30.40.50.6
Total sessions with >9 infusions1.41.72.61.41.51.01.41.01.21.61.11.6
Short access day 1 total inactive lever presses0.10.10.20.40.40.20.40.10.30.40.20.4
Short access day 10 total inactive lever presses0.00.10.3-0.00.10.2-0.10.50.2-0.00.3-0.2
Short access day 1 total infusions0.60.81.61.11.10.41.00.30.61.20.51.2
Short access day 10 total infusions2.93.64.92.12.21.82.01.91.81.71.61.9
Short access total infusions0.50.61.11.01.10.60.90.60.60.80.40.9
Short access day 1 locomotion4.45.46.62.52.62.12.51.92.22.52.12.5
Short access day 10 total locomotion2.64.87.32.22.32.42.12.72.21.72.11.9
Short access total locomotion5.36.47.72.62.82.52.52.62.52.42.52.5
One hour access (0.3 mA shock)0.10.10.40.40.30.40.20.60.1-0.3-0.1-0.4
Compulsive drug intake0.30.30.8-0.4-0.6-0.2-0.30.2-0.6-0.7-0.7-0.9
One hour access (shock baseline)0.10.20.30.40.50.50.30.40.40.20.40.2
Social response proportion0.10.10.20.0-0.00.40.10.40.2-0.30.2-0.4
Social responses0.70.91.51.21.11.11.00.90.90.80.80.5
Social time0.10.10.5-0.1-0.20.4-0.10.20.1-0.70.2-0.7
Soleus weight0.61.73.01.41.41.71.31.51.40.61.40.5
Bone: stiffness0.10.10.40.2-0.00.40.20.60.1-0.4-0.0-0.3
Tibialis anterior weight1.75.78.42.32.62.62.32.02.81.92.91.9
Time to tail flick, vehicle, before self-admin0.30.30.7-0.8-0.7-0.2-0.6-0.0-0.3-0.8-0.2-0.8
Time to tail flick, vehicle, after self-admin0.30.40.7-0.7-0.7-0.3-0.5-0.1-0.5-0.8-0.5-0.8
Time to tail flick, test, before self-admin0.40.40.80.60.30.90.70.90.60.30.50.2
Time to tail flick, test, after self-admin0.10.10.50.30.10.50.20.70.2-0.20.1-0.0
Delta time to tail flick, vehicle, before/after SA0.60.50.8-0.7-0.8-0.6-0.6-0.5-0.8-0.9-0.9-0.8
Delta time to tail flick, test, before/after SA0.50.51.0-0.7-0.7-0.6-0.8-0.2-0.8-1.0-0.8-0.8
Tibia length1.74.65.32.02.12.22.32.02.32.22.31.8
Ambulatory time before self-admin0.10.20.6-0.1-0.1-0.30.2-0.50.10.80.10.7
Ambulatory time after self-admin0.10.10.70.30.10.10.5-0.10.20.80.20.5
Bone: tissue strength0.60.61.4-0.7-0.6-1.1-0.7-1.2-0.9-0.2-0.9-0.3
Total heroin consumption0.10.10.2-0.3-0.3-0.2-0.3-0.3-0.3-0.0-0.2-0.4
Bone: trabecular number4.57.411.2-2.3-2.4-2.2-2.6-2.5-2.8-3.3-2.8-3.3
Bone: trabecular spacing2.02.75.01.31.31.31.61.41.72.21.72.0
Bone: trabecular thickness0.40.51.4-0.3-0.5-0.2-0.5-0.2-0.8-1.2-0.9-1.2
Bone: trabecular tissue density0.30.51.60.20.20.20.50.50.61.20.61.3
Water consumed over 24 hours0.30.41.30.40.70.00.4-0.20.51.10.61.0
Number of responses in last shaping day1.61.72.61.01.31.11.21.01.51.61.51.6