Hub : Genes

Pced1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_008765737.2 0.04 0.04 3.4e-05 0.03 0.04 0.01 0.03 1.7e-04 7.4e-05 9.7e-03 2.4e-04
2 Adipose gene expression Pced1b 0.07 0.07 8.2e-05 0.03 0.04 0.04 0.03 2.4e-04 8.0e-05 8.4e-05 1.2e-04
3 PL alternative TSS XM_008765740.3 0.04 0.04 4.4e-04 0.04 0.03 0.04 0.04 2.7e-05 6.5e-04 8.0e-05 8.3e-05
4 pVTA gene expression Pced1b 0.12 0.09 2.3e-03 0.03 0.06 0.04 0.04 1.4e-02 1.9e-03 1.1e-02 8.4e-03
5 Liver alternative TSS NM_001039454.1 0.04 0.03 1.1e-04 0.02 0.03 0.02 0.02 1.9e-03 1.9e-04 1.1e-03 1.3e-03
6 Adipose intron excision ratio chr7_128505124_128526585 0.05 0.04 1.5e-07 0.05 0.05 0.05 0.05 2.8e-06 1.7e-06 3.8e-06 2.1e-06
7 Adipose isoform ratio XM_008765742.3 0.03 0.02 1.4e-03 0.02 0.02 0.01 0.01 5.0e-03 3.3e-03 1.3e-02 1.2e-02
8 Adipose alternative TSS XM_008765742.3 0.03 0.02 8.3e-04 0.02 0.02 0.02 0.02 2.0e-03 1.9e-03 3.1e-03 3.1e-03
9 NAcc alternative TSS XM_008765740.3 0.02 0.02 3.2e-03 0.02 0.02 0.01 0.02 1.4e-03 5.0e-03 5.8e-03 1.8e-03
10 NAcc gene expression Pced1b 0.06 0.04 1.2e-07 0.08 0.06 0.07 0.07 1.8e-09 4.9e-07 2.4e-08 9.8e-09
11 Adipose mRNA stability Pced1b 0.1 0.05 3.3e-16 0.13 0.13 0.13 0.13 3.5e-14 2.3e-14 3.0e-14 2.0e-14
12 Adipose alternative TSS NM_001039454.1 0.02 0.02 4.4e-03 0.01 0.01 0.01 0.01 1.4e-02 1.8e-02 2.7e-02 4.4e-02
13 Liver alternative TSS NM_001039454.1 0.04 0.03 1.0e-05 0.04 0.04 0.03 0.04 2.6e-05 4.2e-05 3.0e-04 5.0e-05
14 Liver alternative TSS XM_008765740.3 0.04 0.03 1.1e-05 0.04 0.04 0.03 0.04 2.3e-05 3.7e-05 2.4e-04 5.3e-05
15 Liver alternative TSS XM_008765740.3 0.02 0.02 1.3e-03 0.02 0.02 0 0.01 2.7e-03 5.3e-03 1.6e-01 1.5e-02
16 PL alternative TSS XM_008765737.2 0.02 0.02 2.2e-03 0.01 0.02 0.01 0.02 1.6e-02 6.0e-03 2.8e-02 5.4e-03
17 Brain mRNA stability Pced1b 0.09 0.1 1.1e-04 0.05 0.03 0.05 0.05 3.2e-05 4.0e-04 3.7e-05 3.0e-05
18 Liver gene expression Pced1b 0.03 0.04 8.1e-03 0.01 0.01 0.01 0.01 7.2e-03 9.0e-03 3.6e-02 2.1e-02
19 PL alternative TSS NM_001039454.1 0.08 0.09 7.2e-04 0.02 0.03 0.03 0.03 1.5e-03 8.7e-04 2.3e-04 3.2e-04
20 PL alternative TSS XM_008765740.3 0.07 0.08 7.3e-04 0.02 0.03 0.03 0.03 9.8e-04 8.3e-04 3.3e-04 2.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density5.99.813.1-3.43.2-3.3-3.1-3.4-3.63.53.5-3.23.23.33.33.3-3.3-3.3-3.32.23.41.30.8
Area under the delay curve0.80.91.6-1.11.0-1.0-1.2-0.8-1.00.90.9-1.31.21.21.00.9-0.9-0.9-0.6-0.0-0.1-0.9-1.0
BMI with tail2.58.015.8-3.53.5-3.5-4.0-3.0-3.23.02.9-3.13.02.92.92.8-2.8-2.8-2.11.32.1-0.0-0.4
BMI without tail0.51.06.00.1-0.1-0.0-0.40.50.3-0.4-0.40.1-0.2-0.6-0.5-0.60.60.51.0-2.0-1.1-2.3-2.5
Body weight3.816.127.0-5.15.0-4.8-5.2-4.5-4.74.64.5-4.64.44.03.83.7-3.7-3.8-3.62.12.80.50.1
Weight adjusted by age0.80.82.0-1.31.2-0.8-1.4-0.9-1.11.01.0-1.21.00.80.60.7-0.7-0.7-0.6-0.40.3-0.8-0.9
Bone surface7.914.017.2-4.14.1-4.1-4.1-4.0-4.04.03.9-4.04.03.94.04.0-4.0-4.0-3.53.03.02.01.7
Bone volume4.88.210.3-3.23.1-3.2-3.1-3.1-3.23.13.1-3.03.03.03.13.1-3.1-3.1-2.82.22.61.20.9
Breakpoint value in progressive ratio session1.51.63.2-0.80.7-1.0-0.1-1.1-1.11.11.2-1.31.41.31.31.4-1.4-1.4-1.81.51.21.71.6
Number of licking bursts0.40.51.20.4-0.30.70.50.40.6-0.4-0.40.8-0.8-0.9-0.8-0.70.70.70.60.2-0.90.81.1
Context. condit. distance diff. score0.60.71.6-0.70.7-0.9-0.6-0.7-0.70.70.7-0.80.80.80.70.7-0.7-0.7-0.81.11.31.21.1
Locomotion velocity, session 11.31.43.60.8-0.81.20.81.01.0-0.9-0.91.2-1.2-1.2-1.4-1.51.51.51.1-1.1-1.9-0.8-0.6
Locomotion distance, session 13.44.36.72.0-2.12.12.12.11.9-1.9-1.91.7-1.8-1.9-2.2-2.32.32.31.6-2.6-2.0-2.3-2.3
Locomotion velocity, session 20.60.74.20.5-0.60.50.30.50.4-0.5-0.50.4-0.5-0.6-0.5-0.50.50.50.6-0.8-1.2-2.0-2.0
Locomotion distance, session 22.63.66.71.8-2.01.71.71.91.7-1.8-1.81.6-1.6-1.7-1.8-1.91.91.91.5-2.6-1.7-2.4-2.4
Locomotion velocity, session 33.43.94.51.9-2.01.91.82.01.9-1.9-1.92.0-2.0-2.0-2.1-2.02.02.01.9-2.0-2.0-2.1-2.0
Locomotion distance, session 33.84.27.12.3-2.52.12.72.12.0-2.0-1.92.3-2.3-2.2-2.4-2.32.32.31.3-1.5-1.1-1.0-0.9
Stereotopy head waving bouts, day 30.60.71.4-0.91.0-1.0-1.2-0.8-0.70.70.7-1.11.10.91.01.1-1.1-1.1-0.6-0.00.4-0.1-0.1
Stereotopy head waving duration, day 30.20.20.8-0.40.5-0.5-0.9-0.2-0.20.10.1-0.60.60.40.50.5-0.5-0.50.1-0.6-0.2-0.5-0.5
Locomotion velocity, session 70.10.10.40.2-0.20.30.30.20.2-0.2-0.20.5-0.5-0.5-0.6-0.50.50.50.2-0.5-0.60.00.1
Locomotion distance, session 71.41.82.71.3-1.31.51.51.41.3-1.3-1.31.6-1.6-1.5-1.6-1.61.61.61.1-0.6-1.0-0.1-0.0
Stereotopy head waving bouts, day 71.21.42.1-1.21.2-1.4-1.1-1.3-1.21.21.2-1.21.21.11.11.2-1.2-1.2-1.20.51.31.21.1
Stereotopy head waving duration, day 72.53.03.8-1.71.7-1.9-1.5-1.9-1.81.81.8-1.81.81.81.81.9-1.9-1.9-1.81.21.41.71.6
Locomotion velocity, session 80.20.20.5-0.50.5-0.7-0.7-0.5-0.40.40.4-0.50.50.40.40.4-0.4-0.4-0.20.2-0.1-0.2-0.3
Locomotion distance, session 80.60.91.61.1-1.30.71.11.10.9-1.0-1.00.7-0.7-0.8-1.0-1.01.01.00.5-1.1-0.3-1.2-1.3
Degree of sensitization distance0.30.31.1-0.80.9-0.4-1.0-0.5-0.40.40.4-0.50.50.40.50.5-0.5-0.50.10.7-0.00.60.6
Degree of sensitization stereotypy1.31.42.5-1.11.1-1.3-0.9-1.2-1.11.21.2-1.11.11.11.01.2-1.2-1.2-1.31.11.21.61.6
Conditioned locomotion0.30.41.00.3-0.20.4-0.10.50.5-0.5-0.60.6-0.6-0.7-0.7-0.70.70.71.0-0.8-0.7-0.8-0.8
Cocaine response after cond. corrected1.01.29.20.0-0.1-0.2-0.70.40.3-0.4-0.5-0.30.3-0.00.10.1-0.1-0.10.8-1.4-1.3-2.9-3.0
Cocaine response after cond. not corrected2.12.39.41.1-1.10.90.51.41.3-1.4-1.40.8-0.8-1.1-1.0-1.01.01.01.6-1.7-2.1-3.1-3.1
Cocaine response before conditioning4.14.98.82.6-2.52.53.02.32.4-2.3-2.22.6-2.6-2.4-2.5-2.52.52.41.7-0.5-1.40.40.7
Saline control response0.10.10.60.4-0.40.20.20.40.4-0.4-0.40.2-0.2-0.2-0.2-0.20.20.20.3-0.0-0.0-0.7-0.8
Bone: connectivity density4.67.39.0-2.92.8-2.9-2.8-2.9-3.02.92.9-2.92.92.93.03.0-3.0-3.0-2.62.12.60.90.6
Bone: cortical apparent density1.21.54.81.0-0.90.70.21.21.2-1.3-1.30.6-0.6-0.8-0.7-0.70.70.71.5-2.1-1.7-2.2-2.1
Bone: cortical area7.811.715.2-3.83.6-3.9-3.4-3.7-3.83.83.8-3.73.73.73.53.5-3.5-3.5-3.62.42.91.81.4
Bone: cortical porosity1.61.72.61.5-1.51.51.61.41.5-1.5-1.41.4-1.4-1.3-1.4-1.41.41.41.0-0.5-1.0-0.3-0.2
Bone: cortical porosity1.51.72.71.6-1.61.41.61.51.5-1.5-1.51.3-1.3-1.2-1.3-1.31.31.31.0-0.5-1.0-0.4-0.3
Bone: cortical thickness3.35.47.8-2.52.3-2.8-2.2-2.5-2.72.62.6-2.72.72.62.42.4-2.4-2.4-2.61.11.90.40.1
Bone: cortical thickness0.30.32.3-0.30.0-0.4-0.0-0.2-0.50.40.4-0.30.30.30.00.0-0.00.0-0.5-0.90.6-1.2-1.5
Bone: cortical tissue density1.31.74.91.1-1.00.80.31.31.4-1.4-1.50.7-0.7-0.9-0.8-0.80.80.81.7-2.2-1.7-2.2-2.1
Condit. Reinf. active minus inactive responses0.50.52.00.5-0.50.50.20.60.5-0.6-0.60.6-0.7-0.6-0.5-0.60.60.60.9-1.1-0.7-1.4-1.4
Condit. Reinf. active-inactive response ratio0.10.10.4-0.30.2-0.3-0.3-0.2-0.30.20.2-0.10.10.20.30.2-0.2-0.2-0.0-0.40.2-0.6-0.6
Condit. Reinf. active responses1.21.52.41.0-1.11.20.81.21.1-1.1-1.11.3-1.3-1.3-1.2-1.31.31.31.4-1.4-0.9-1.5-1.5
Condit. Reinf. inactive responses3.74.46.12.0-2.02.31.92.12.1-2.1-2.12.3-2.2-2.2-2.5-2.52.52.52.1-1.7-1.6-1.2-1.1
Incentive salience index mean0.20.21.4-0.00.00.0-0.30.20.1-0.2-0.20.1-0.2-0.20.10.0-0.0-0.00.5-0.6-0.6-1.2-1.2
Condit. Reinf. lever presses0.30.41.9-0.30.4-0.3-0.9-0.1-0.10.0-0.0-0.40.40.20.60.6-0.6-0.60.3-0.2-0.9-1.3-1.4
Condit. Reinf. active minus inactive responses0.10.10.30.1-0.10.20.10.20.2-0.2-0.20.4-0.4-0.3-0.5-0.50.50.50.40.4-0.4-0.2-0.2
Condit. Reinf. active-inactive response ratio0.60.61.50.5-0.61.00.80.60.4-0.4-0.41.0-1.0-0.9-1.2-1.21.21.20.6-0.30.0-0.1-0.1
Condit. Reinf. active responses0.30.41.20.5-0.40.50.30.60.7-0.6-0.60.7-0.7-0.7-0.8-0.80.80.80.80.0-1.1-0.5-0.3
Condit. Reinf. inactive responses0.91.23.41.0-0.80.90.71.11.3-1.2-1.21.0-1.0-1.1-1.0-1.01.01.01.3-0.5-1.9-0.8-0.6
Condit. Reinf. lever presses0.10.11.3-0.10.0-0.20.1-0.3-0.20.30.3-0.20.20.2-0.0-0.00.00.0-0.51.10.30.30.3
Condit. Reinf. lever reinforcers received0.50.71.10.8-0.70.80.70.80.9-0.8-0.80.9-0.9-0.9-1.0-1.01.01.00.9-0.1-1.0-0.6-0.4
Conditioned reinforcement - actives1.01.02.01.2-1.31.20.91.11.0-1.1-1.11.4-0.9-0.8-0.7-0.70.70.41.0-1.0-0.2-1.3-1.4
Conditioned reinforcement - inactives0.70.71.61.0-1.10.90.90.90.8-0.9-0.91.3-0.9-0.7-0.7-0.70.70.50.9-0.90.4-0.9-1.1
Conditioned locomotion0.10.10.30.5-0.50.10.30.40.4-0.4-0.40.3-0.2-0.1-0.2-0.20.20.00.3-0.50.2-0.1-0.1
Patch foraging indifference point 0 sec0.91.43.81.3-1.41.61.90.90.9-0.8-0.71.7-1.8-1.5-1.3-1.41.41.30.2-0.1-0.10.30.3
Patch foraging indifference point AUC0.10.10.20.2-0.20.20.40.0-0.00.00.00.1-0.00.1-0.2-0.10.10.1-0.3-0.50.40.50.5
Delay disc. indifference point, 0s delay0.60.61.6-1.11.0-1.3-1.0-0.9-1.01.00.9-1.00.90.80.50.5-0.5-0.5-0.7-0.2-0.4-0.2-0.3
Delay disc. indifference point, 16s delay1.11.12.0-1.21.2-1.0-1.4-1.0-1.11.01.0-1.41.31.41.11.1-1.1-1.1-0.80.70.2-0.0-0.1
Delay disc. indifference point, 2s delay0.30.31.0-0.70.7-0.3-1.0-0.4-0.50.40.4-0.40.50.40.50.4-0.4-0.40.2-0.3-0.6-0.9-0.9
Delay disc. indifference point, 24s delay0.80.81.4-1.11.2-1.0-1.1-1.0-1.01.01.0-1.11.01.00.80.7-0.7-0.7-0.80.8-0.20.50.5
Delay disc. indifference point, 4s delay0.20.21.1-0.50.4-0.5-0.8-0.2-0.30.20.2-0.40.20.30.60.5-0.5-0.50.3-0.3-0.1-0.9-1.1
Delay disc. indifference point, 8s delay2.52.64.4-1.91.7-2.0-1.8-1.7-1.81.71.7-2.12.02.01.61.6-1.6-1.6-1.50.61.10.1-0.1
Indifference point function ln k1.42.03.7-1.91.9-1.9-1.9-1.7-1.71.71.7-1.41.41.11.11.1-1.1-1.1-1.20.90.70.30.1
Indifference point function log k1.42.03.7-1.91.9-1.9-1.9-1.7-1.71.71.7-1.41.41.11.11.1-1.1-1.1-1.20.90.70.30.1
Patch foraging total patch changes 0 sec0.81.33.41.2-1.31.41.80.90.9-0.8-0.71.6-1.7-1.5-1.3-1.31.31.30.20.0-0.00.50.5
Patch foraging total patch changes 12 sec0.50.62.20.9-0.90.91.50.40.5-0.4-0.30.9-0.9-0.4-0.5-0.50.50.5-0.50.70.71.31.3
Patch foraging total patch changes 18 sec1.62.04.31.6-1.52.02.11.21.4-1.3-1.21.9-1.8-1.3-1.3-1.31.31.20.70.00.01.51.8
Patch foraging total patch changes 24 sec0.70.92.80.9-0.71.11.00.81.0-0.9-0.81.2-1.0-1.0-0.9-0.80.80.70.60.6-0.01.51.7
Patch foraging total patch changes 6 sec1.32.04.61.6-1.71.92.11.31.3-1.2-1.12.0-2.0-1.6-1.4-1.41.41.40.7-0.9-0.40.10.2
Patch foraging time to switch 0 sec2.23.44.92.2-2.01.91.82.12.2-2.2-2.22.0-2.0-1.8-1.6-1.61.61.62.0-0.9-1.8-1.3-1.1
Patch foraging water rate 0 sec3.96.38.2-2.82.7-2.7-2.5-2.8-2.92.92.9-2.62.72.52.42.4-2.4-2.5-2.72.02.41.71.4
Patch foraging water rate 12 sec2.53.85.8-2.32.3-2.4-2.3-2.2-2.12.22.2-2.22.11.81.61.6-1.6-1.6-1.72.01.71.31.2
Patch foraging water rate 18 sec0.40.51.7-1.01.0-1.3-1.2-0.8-0.80.80.8-1.00.80.40.40.4-0.4-0.5-0.60.40.20.10.0
Patch foraging water rate 24 sec4.56.38.5-2.42.2-2.8-1.9-2.6-2.62.72.7-2.32.22.32.62.6-2.6-2.6-2.92.22.82.52.3
Patch foraging water rate 6 sec4.26.17.9-2.72.6-2.8-2.3-2.8-2.82.82.8-2.32.22.32.32.3-2.3-2.4-2.72.22.22.11.9
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.40.4-0.3-0.6-0.3-0.40.30.30.1-0.00.30.40.4-0.4-0.4-0.0-0.1-0.2-0.6-0.7
Distance traveled before self-admin0.50.51.90.9-1.01.31.40.60.6-0.5-0.50.8-0.5-0.8-0.7-0.70.70.70.2-0.10.00.60.6
Distance traveled after self-admin0.70.73.5-0.1-0.1-0.80.2-0.5-0.50.50.5-0.80.91.00.90.9-0.9-0.8-1.21.01.91.00.7
Extensor digitorum longus weight4.718.424.8-4.94.9-4.8-5.0-4.7-4.74.74.6-4.74.74.54.54.5-4.5-4.5-3.93.33.01.41.0
Bone: elastic displacement2.83.16.62.2-2.22.12.61.81.8-1.8-1.72.0-2.0-1.8-2.0-2.02.02.01.1-0.9-0.60.20.4
Bone: elastic work0.10.10.50.2-0.20.10.4-0.1-0.10.10.1-0.00.00.20.10.1-0.1-0.2-0.40.20.70.30.3
Bone: endosteal estimation6.514.217.9-4.14.2-3.7-3.9-4.0-3.83.93.9-3.73.73.83.73.7-3.7-3.8-3.43.93.13.63.5
Bone: endosteal perimeter5.912.214.9-3.83.9-3.5-3.5-3.7-3.63.73.6-3.43.43.53.43.4-3.4-3.5-3.33.43.13.43.2
Epididymis fat weight0.51.12.6-1.11.0-1.6-1.4-0.9-1.00.90.9-1.51.31.20.90.9-0.9-0.9-0.8-0.30.6-0.9-1.1
Delta time in closed arm before/after self-admin0.00.00.2-0.20.3-0.4-0.4-0.1-0.10.10.1-0.00.20.20.20.2-0.2-0.10.1-0.00.20.20.3
Delta time in open arm before/after self-admin2.32.23.41.8-1.81.81.81.61.6-1.6-1.61.3-1.4-1.5-1.4-1.41.41.31.3-1.3-1.1-0.9-0.8
Diff in mean of infusions in LGA sessions0.70.81.2-0.90.8-1.1-0.8-0.9-1.10.90.9-0.50.71.01.01.0-1.0-1.0-1.00.20.8-0.8-1.0
Delay discount exponential model param0.70.71.31.0-0.90.81.10.70.9-0.8-0.81.1-1.1-1.1-0.9-0.90.90.90.50.00.10.81.0
Extinction: sum of active levers before priming2.02.04.3-1.01.0-0.6-0.4-1.3-1.31.31.3-1.31.41.31.51.5-1.5-1.4-1.81.61.52.12.0
Active lever presses in extinction session 60.30.31.1-0.60.5-0.4-0.1-0.6-0.70.80.8-0.10.10.2-0.00.0-0.0-0.1-0.90.10.61.01.0
Bone: final force7.812.615.9-3.93.9-4.0-3.9-3.8-3.93.83.7-3.83.83.73.93.9-3.9-3.9-3.32.62.81.71.4
Bone: final moment7.812.716.2-3.93.9-4.0-4.0-3.8-3.93.83.7-3.83.83.83.93.9-3.9-3.9-3.32.63.01.71.3
Food consumed during 24 hour testing period0.91.11.8-1.11.1-1.3-1.3-1.1-1.11.01.0-1.31.31.21.21.1-1.1-1.1-0.80.50.70.0-0.1
Glucose0.10.10.8-0.20.2-0.1-0.60.10.1-0.2-0.2-0.10.0-0.10.00.0-0.0-0.00.6-0.9-0.4-0.4-0.3
Heart weight0.30.42.00.1-0.10.4-0.20.40.4-0.4-0.50.2-0.5-0.4-0.3-0.30.30.30.7-1.4-1.0-1.3-1.3
Delay discount hyperbolic model param0.60.71.30.9-0.80.71.10.70.8-0.7-0.71.0-1.0-1.0-0.9-0.80.80.80.30.10.21.01.1
Intermittent access intake day 1-15 change1.71.73.01.0-1.00.90.51.21.2-1.2-1.21.1-0.9-1.2-1.6-1.71.71.71.4-1.0-1.4-1.6-1.6
Intermittent access intake escalation1.41.43.10.9-0.80.70.41.11.0-1.1-1.11.0-0.8-1.0-1.4-1.51.51.41.3-1.2-1.3-1.7-1.7
Intermittent access intake escalation 20.60.61.50.8-0.80.80.50.80.8-0.9-0.90.9-0.6-0.5-0.7-0.70.70.70.9-0.7-0.4-1.1-1.2
Intermitt. access day 1 inactive lever presses1.81.93.51.7-1.61.81.71.41.6-1.5-1.51.9-1.7-1.4-1.4-1.31.31.11.2-0.3-0.30.60.7
Intermitt. access day 15 inactive lever presses1.82.03.71.2-1.11.10.91.41.3-1.4-1.41.7-1.4-1.4-1.8-1.71.71.51.6-1.9-0.9-0.9-0.9
Intermitt. access escalation Index1.21.06.10.2-0.10.70.5-0.3-0.10.20.20.5-0.10.30.91.1-1.1-1.1-0.51.60.72.32.5
Intermittent access day 1 total infusions1.21.32.41.3-1.51.41.51.21.1-1.1-1.11.0-1.3-1.1-1.1-1.11.11.00.9-1.5-0.1-0.9-1.0
Intermittent access day 15 total infusions3.03.44.41.8-1.81.91.41.81.8-1.8-1.82.0-1.8-1.8-1.9-1.91.91.81.9-2.0-1.1-2.1-2.1
Intermittent access terminal intake (last 3 days)2.83.14.21.7-1.71.81.21.81.8-1.8-1.81.9-1.7-1.7-1.8-1.71.71.62.0-1.7-1.3-2.0-2.0
Intermittent access total infusions1.92.12.81.6-1.71.61.51.51.5-1.5-1.51.5-1.5-1.4-1.5-1.51.51.41.3-1.4-0.4-1.3-1.3
Intermittent access day 1 locomotion1.41.52.51.1-1.11.10.91.31.3-1.3-1.30.9-1.2-1.3-1.5-1.61.61.51.4-1.3-0.8-0.4-0.3
Intermittent access day 15 total locomotion1.01.11.61.0-1.01.20.91.11.1-1.1-1.11.3-1.2-1.2-1.1-1.21.21.11.2-0.9-0.7-0.3-0.2
Intermittent access total locomotion1.61.82.71.6-1.51.31.31.61.6-1.6-1.61.1-1.3-1.4-1.5-1.51.51.41.4-1.2-1.1-0.4-0.2
Intermittent access standard deviation1.61.73.91.0-1.00.90.61.31.1-1.3-1.30.7-0.9-1.0-1.6-1.61.61.41.4-1.6-0.4-1.9-2.0
Left kidney weight0.41.12.0-1.00.8-0.9-1.1-0.8-1.10.90.9-1.11.00.91.21.2-1.2-1.2-0.8-1.11.1-1.1-1.4
Right kidney weight1.54.27.6-2.62.6-2.0-2.8-2.2-2.32.22.1-2.22.02.12.32.2-2.2-2.3-1.60.51.30.60.4
Cocaine induced anxiety1.61.94.5-1.31.4-1.6-1.4-1.3-1.11.21.2-1.01.21.31.11.0-1.0-1.1-0.91.81.72.12.1
Post-drug Anxiety5.35.97.3-2.32.4-2.5-2.5-2.4-2.32.32.3-2.42.52.62.72.6-2.6-2.7-1.92.62.62.32.1
Baseline Anxiety1.41.53.1-1.10.9-0.6-0.7-1.3-1.41.31.3-1.11.11.31.71.8-1.8-1.6-1.60.91.00.1-0.0
Tail length0.51.54.60.6-0.60.80.30.80.8-0.8-0.80.5-0.5-1.2-1.1-1.11.11.01.1-2.1-2.0-2.1-2.1
Length with tail1.14.17.0-2.62.6-2.2-2.5-2.4-2.52.52.4-2.32.31.91.81.8-1.8-1.9-2.01.21.00.30.1
Length without tail6.514.317.8-4.24.2-3.9-3.9-4.1-4.24.24.1-3.83.73.93.83.8-3.8-3.7-3.93.63.62.62.2
Times rat made contact with spout0.10.10.3-0.30.3-0.5-0.5-0.3-0.30.30.3-0.30.30.20.20.2-0.2-0.3-0.0-0.2-0.2-0.5-0.5
Lifetime Intake1.41.62.51.4-1.51.41.41.31.2-1.2-1.21.6-1.4-1.2-1.4-1.31.31.21.1-1.3-0.1-1.0-1.0
Liver weight, left3.04.76.8-1.91.9-2.1-1.8-2.0-1.91.91.9-2.42.42.62.52.4-2.4-2.4-2.11.92.32.12.0
Liver weight, right2.13.55.9-1.81.7-1.4-1.3-1.9-1.91.91.9-1.91.92.11.91.8-1.8-1.7-2.01.62.42.22.0
Locomotor activity0.71.11.81.2-1.11.11.11.11.2-1.2-1.21.3-1.3-1.3-0.9-0.80.80.81.0-0.9-1.0-0.10.0
Locomotor testing distance1.82.95.42.0-2.02.02.31.81.8-1.8-1.72.0-2.2-1.9-1.7-1.71.71.61.3-1.0-1.30.30.4
Locomotor testing rearing1.72.65.61.9-1.92.42.41.61.6-1.5-1.42.1-2.2-1.7-1.6-1.51.51.51.1-0.6-0.80.60.7
Locomotion in novel chamber0.30.30.7-0.90.8-0.2-0.8-0.7-0.80.70.7-0.20.30.40.50.6-0.6-0.6-0.50.2-0.0-0.4-0.4
Locomotion in novel chamber post-restriction0.50.61.2-0.90.9-0.8-1.1-0.8-0.70.80.8-0.80.70.70.80.8-0.8-0.8-0.40.8-0.1-0.1-0.1
Fecal boli incidents, locomotor time 10.90.94.70.9-1.10.00.50.80.7-0.8-0.80.3-0.2-0.4-0.2-0.20.20.20.7-1.9-0.8-2.0-2.2
Change in fecal boli incidents, locomotor task0.40.41.3-0.80.90.1-0.6-0.7-0.60.70.70.0-0.2-0.00.40.4-0.4-0.4-0.31.10.31.01.1
Time >=10cm from walls, locomotor time 10.90.92.4-0.90.6-0.9-0.5-1.0-1.21.21.2-1.31.11.00.90.9-0.9-0.9-1.6-0.11.00.30.1
Bouts of movement, locomotor time 10.40.41.6-0.40.3-0.7-0.5-0.3-0.40.30.3-0.71.30.90.80.6-0.6-0.6-0.3-0.2-0.6-1.0-1.0
Total resting periods, locomotor time 10.20.31.50.2-0.2-0.10.00.20.2-0.2-0.2-0.10.70.30.30.2-0.2-0.20.2-0.6-0.8-1.2-1.2
Rest time, locomotor task time 10.00.10.30.1-0.20.40.50.00.00.00.00.4-0.1-0.1-0.10.0-0.0-0.0-0.30.1-0.40.20.3
Distance moved, locomotor task time 10.10.11.40.2-0.40.00.6-0.0-0.10.10.1-0.1-0.00.2-0.0-0.20.20.2-0.6-0.11.20.60.5
Vertical activity count, locomotor time 11.21.23.2-1.10.8-1.2-0.8-1.2-1.41.31.3-1.11.01.21.41.1-1.1-1.1-1.50.21.80.1-0.3
Time >=10cm from walls, locomotor time 20.10.10.50.3-0.50.30.70.10.0-0.0-0.0-0.10.10.20.10.0-0.0-0.0-0.5-0.30.60.30.2
Bouts of movement, locomotor time 23.23.55.0-1.92.0-1.8-1.9-1.8-1.71.81.8-2.12.22.01.91.8-1.8-1.8-1.52.01.41.81.8
Total resting periods, locomotor time 22.93.14.6-1.92.0-1.7-1.9-1.7-1.71.71.7-2.02.11.91.71.6-1.6-1.6-1.41.91.11.71.7
Rest time, locomotor task time 20.10.20.9-0.30.5-0.0-0.6-0.2-0.10.10.10.0-0.2-0.30.00.1-0.1-0.10.40.1-1.0-0.8-0.7
Distance moved, locomotor task time 20.30.32.50.4-0.60.31.0-0.0-0.10.10.2-0.10.40.50.10.1-0.1-0.1-0.90.41.60.80.6
Vertical activity count, locomotor time 20.70.71.4-0.60.5-0.7-0.4-0.8-0.80.80.8-0.80.90.91.10.9-0.9-0.9-1.10.81.20.90.8
Light reinforcement 12.13.75.62.1-2.02.12.02.02.1-2.1-2.02.1-2.3-2.4-2.1-2.02.02.11.9-0.9-1.8-0.9-0.6
Light reinforcement 22.02.75.11.3-1.11.20.51.61.7-1.7-1.71.2-1.5-1.8-1.7-1.51.51.62.3-1.7-2.2-2.1-1.8
Bone: marrow area6.714.518.2-4.14.3-3.8-3.9-4.0-3.93.93.9-3.73.73.83.73.7-3.7-3.8-3.54.03.23.73.6
Bone: maximum diameter3.87.18.9-3.03.0-2.8-2.6-2.9-2.92.92.9-2.82.82.82.52.5-2.5-2.6-2.72.51.82.22.1
Bone: maximum force9.616.620.8-4.64.5-4.5-4.5-4.4-4.44.44.3-4.34.34.34.44.3-4.3-4.4-3.83.23.32.11.8
Bone: maximum moment9.516.420.6-4.54.5-4.5-4.5-4.4-4.44.34.3-4.34.34.24.34.3-4.3-4.4-3.73.13.42.11.7
Mean time between licks in bursts0.71.02.80.9-0.90.70.51.11.1-1.1-1.10.7-0.7-0.9-0.7-0.70.70.81.2-1.4-1.7-1.3-1.1
Mean num. licks in bursts0.40.52.7-0.20.0-0.7-0.3-0.2-0.40.20.2-0.70.70.70.60.5-0.5-0.6-0.4-0.70.7-1.3-1.7
Cd content in liver1.11.22.60.7-0.60.90.21.01.1-1.1-1.11.0-1.0-1.1-1.0-1.01.01.01.5-1.0-1.6-1.4-1.3
Co content in liver0.30.31.10.6-0.70.40.50.60.5-0.6-0.60.4-0.4-0.4-0.3-0.30.30.30.3-1.0-0.7-1.0-1.0
Cu content in liver2.42.96.5-1.51.5-1.2-1.1-1.7-1.61.61.7-1.41.41.51.61.6-1.6-1.6-1.82.21.82.52.5
Fe content in liver0.50.63.90.2-0.20.40.7-0.1-0.10.10.20.2-0.20.0-0.0-0.00.00.0-0.61.01.42.02.0
K content in liver0.80.81.4-1.11.0-1.0-1.2-1.0-1.11.11.0-1.01.01.00.90.9-0.9-0.9-0.6-0.30.90.1-0.0
Mg content in liver0.10.10.8-0.1-0.00.10.1-0.1-0.20.20.20.1-0.1-0.1-0.2-0.20.20.2-0.1-0.90.2-0.1-0.2
Mn content in liver0.10.10.5-0.40.5-0.1-0.7-0.2-0.20.10.1-0.30.30.30.30.3-0.3-0.30.2-0.2-0.0-0.4-0.4
Na content in liver0.60.63.3-0.50.6-0.0-0.2-0.6-0.60.60.6-0.10.10.30.10.1-0.1-0.1-0.61.21.21.81.8
Rb content in liver0.30.43.9-0.00.00.10.4-0.1-0.10.20.20.1-0.1-0.1-0.3-0.30.30.3-0.30.40.31.82.0
Se content in liver0.91.12.60.8-0.81.00.51.00.9-1.0-1.01.0-1.0-1.0-0.9-0.90.90.91.2-1.6-0.7-1.5-1.6
Sr content in liver1.31.23.5-1.01.1-1.0-1.1-1.0-0.80.90.9-1.01.01.01.01.0-1.0-1.0-0.71.90.81.51.5
Zn content in liver0.40.41.50.5-0.60.71.00.30.3-0.2-0.20.6-0.6-0.5-0.6-0.70.70.7-0.10.10.31.11.2
Bone: minimum diameter6.211.514.1-3.83.7-3.6-3.4-3.7-3.73.73.7-3.53.53.53.33.3-3.3-3.4-3.53.12.92.62.4
Time in familiar zone, hab. session 10.20.20.60.4-0.50.60.50.40.4-0.4-0.40.5-0.4-0.4-0.5-0.50.50.50.4-0.4-0.3-0.7-0.7
Time in novel zone, hab. session 10.20.21.1-0.30.4-0.4-0.4-0.3-0.10.20.2-0.20.20.10.20.2-0.2-0.2-0.00.60.20.91.0
Total zone transitions, hab. session 10.40.51.00.7-0.70.60.60.70.7-0.7-0.70.4-0.4-0.5-0.6-0.80.80.80.4-0.9-1.0-1.0-0.9
Total locomotion distance, hab. session 10.10.21.30.3-0.30.10.10.30.2-0.3-0.3-0.00.0-0.1-0.2-0.20.20.20.1-0.9-0.2-1.1-1.1
Locomotion velocity, hab. session 10.10.10.70.1-0.20.10.10.10.0-0.1-0.1-0.10.1-0.0-0.2-0.10.10.1-0.3-0.80.1-0.7-0.7
Time in familiar zone, hab. session 20.00.00.3-0.10.10.1-0.0-0.2-0.20.20.20.3-0.3-0.20.10.2-0.2-0.2-0.20.50.30.10.0
Time in novel zone, hab. session 20.10.10.30.10.0-0.1-0.20.20.4-0.3-0.3-0.20.20.1-0.2-0.30.30.30.5-0.1-0.30.30.5
Total zone transitions, hab. session 20.30.41.70.4-0.50.40.50.50.3-0.4-0.40.3-0.2-0.3-0.5-0.60.60.60.2-1.3-0.6-1.2-1.2
Total locomotion distance, hab. session 20.40.51.80.5-0.70.60.80.60.4-0.4-0.40.5-0.5-0.5-0.9-0.80.80.80.2-1.4-0.2-1.0-1.0
Locomotion velocity, hab. session 20.20.31.90.3-0.50.40.50.30.1-0.2-0.20.2-0.2-0.3-0.6-0.60.60.6-0.1-1.4-0.1-0.9-1.0
Novel to familiar place preference ratio0.60.61.4-0.91.0-0.9-1.0-0.8-0.80.80.8-0.80.80.60.60.7-0.7-0.7-0.41.20.40.80.9
Novelty place preference0.30.30.8-0.60.7-0.6-0.8-0.5-0.40.50.5-0.50.50.30.30.4-0.4-0.4-0.00.90.10.60.7
Time in novel zone, NPP test0.20.20.8-0.50.6-0.5-0.7-0.4-0.30.30.3-0.40.40.20.20.3-0.3-0.30.10.90.20.60.8
Total zone transitions, NPP test1.21.75.81.2-1.41.11.31.31.1-1.1-1.10.8-0.8-0.8-1.2-1.31.31.30.6-2.4-1.1-1.8-1.8
Total locomotion distance, NPP test2.93.98.12.0-2.11.92.02.01.8-1.8-1.81.8-1.8-1.8-2.1-2.12.12.11.4-2.8-1.3-2.1-2.1
Locomotion velocity, NPP test1.92.76.71.5-1.71.51.61.51.3-1.4-1.41.3-1.3-1.4-1.7-1.71.71.71.0-2.6-1.2-2.1-2.1
Intraocular pressure6.08.313.93.7-3.73.13.73.33.3-3.3-3.33.2-3.2-2.9-2.8-2.82.82.72.2-2.0-1.8-0.9-0.7
Delta distance traveled before/after self-admin0.50.51.9-0.50.5-1.4-0.5-0.6-0.60.60.6-0.70.50.90.60.7-0.7-0.6-1.00.71.20.20.1
Delta ambulatory time before/after self-admin0.30.41.6-0.40.4-1.3-0.5-0.5-0.50.50.5-0.50.30.80.60.7-0.7-0.6-0.70.70.90.20.1
Parametrial fat weight0.40.92.01.2-1.40.61.11.10.9-1.0-1.00.7-0.6-0.8-0.9-0.80.80.80.4-1.00.1-1.1-1.2
Pavlov. Cond. lever latency0.40.52.9-0.30.2-0.10.3-0.4-0.40.50.50.0-0.10.2-0.3-0.20.20.2-0.70.71.41.71.7
Pavlov. Cond. magazine entry latency0.10.10.40.1-0.1-0.20.10.0-0.0-0.0-0.0-0.30.30.30.40.4-0.4-0.4-0.40.10.2-0.5-0.7
Pavlov. Cond. change in total contacts0.20.21.20.10.00.1-0.40.30.3-0.4-0.40.1-0.1-0.20.20.1-0.1-0.10.7-0.0-1.0-1.1-1.0
Pavlov. Cond. index score0.20.30.8-0.30.3-0.5-0.6-0.3-0.20.20.2-0.70.70.50.90.8-0.8-0.8-0.30.4-0.3-0.5-0.5
Pavlov. Cond. latency score0.20.30.8-0.10.2-0.4-0.5-0.1-0.10.0-0.0-0.60.60.40.80.7-0.7-0.7-0.00.1-0.6-0.9-0.9
Pavlov. Cond. lever contacts0.60.72.70.7-0.60.50.20.80.8-0.9-0.90.4-0.4-0.6-0.2-0.30.30.31.0-0.9-1.6-1.6-1.6
Pavlov. Cond. magazine entry number0.10.10.3-0.00.00.30.10.00.00.00.00.3-0.3-0.3-0.5-0.40.40.40.2-0.20.10.50.6
Pavlov. Cond. intertrial magazine entries0.80.91.70.8-0.81.00.70.90.9-0.9-0.91.0-1.0-1.0-1.3-1.21.21.21.1-0.9-0.6-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.60.81.7-0.70.7-0.9-0.9-0.7-0.70.60.6-1.11.10.91.31.2-1.2-1.2-0.80.80.1-0.2-0.2
Pavlov. Cond. response bias0.10.11.10.3-0.3-0.00.10.20.2-0.2-0.3-0.10.10.00.30.3-0.3-0.3-0.0-0.2-0.5-1.0-1.0
Pavlov. Cond. lever latency0.10.10.8-0.10.10.0-0.20.20.2-0.2-0.20.2-0.2-0.2-0.1-0.10.10.00.5-0.9-0.3-0.3-0.2
Pavlov. Cond. magazine entry latency0.20.20.6-0.50.4-0.2-0.3-0.5-0.60.60.6-0.40.40.40.40.4-0.4-0.4-0.60.30.80.20.1
Pavlov. Cond. change in total contacts0.60.91.3-1.01.0-0.8-0.9-1.1-1.11.11.1-1.01.00.91.00.9-0.9-0.9-1.01.20.70.20.1
Pavlov. Cond. index score0.20.30.7-0.40.3-0.3-0.1-0.6-0.70.70.7-0.50.50.50.40.4-0.4-0.4-0.80.70.80.40.2
Pavlov. Cond. latency score0.30.40.9-0.50.4-0.4-0.2-0.7-0.80.80.8-0.60.60.60.50.5-0.5-0.5-0.90.70.90.40.3
Pavlov. Cond. lever contacts0.10.10.50.4-0.60.40.70.20.1-0.1-0.10.3-0.3-0.3-0.4-0.40.40.4-0.20.50.20.0-0.1
Pavlov. Cond. magazine entry number0.80.91.41.1-1.10.71.01.21.2-1.2-1.20.9-0.9-0.9-0.9-0.90.90.90.9-0.8-0.9-0.8-0.7
Pavlov. Cond. intertrial magazine entries1.21.52.51.6-1.60.91.61.51.5-1.5-1.41.3-1.3-1.2-1.3-1.21.21.21.1-0.8-0.8-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.70.5-0.5-0.4-0.8-0.90.91.0-0.70.70.70.60.6-0.6-0.6-1.00.81.00.50.4
Pavlov. Cond. response bias0.10.10.20.3-0.40.40.50.20.1-0.1-0.10.3-0.3-0.3-0.3-0.40.40.4-0.10.30.1-0.1-0.2
Time in closed arm before self-admin0.20.20.8-0.80.8-0.8-0.9-0.5-0.60.60.6-0.70.30.2-0.1-0.20.2-0.0-0.3-0.2-0.5-0.3-0.3
Time in closed arm after self-admin0.10.10.6-0.40.4-0.0-0.1-0.3-0.30.40.40.4-0.5-0.2-0.4-0.40.40.4-0.2-0.2-0.20.60.7
Time in open arm before self-admin0.70.72.3-0.91.1-0.7-0.9-0.8-0.70.80.7-0.60.80.60.30.4-0.4-0.3-0.31.30.91.41.5
Time in open arm after self-admin0.30.41.00.6-0.40.70.30.70.8-0.8-0.80.1-0.1-0.6-0.6-0.60.60.61.0-0.4-0.7-0.5-0.4
Bone: periosteal estimation9.720.124.4-4.94.9-4.8-4.5-4.8-4.84.84.8-4.74.74.74.54.5-4.5-4.5-4.44.03.83.53.2
Bone: periosteal perimeter8.714.418.0-4.24.1-4.1-3.8-4.2-4.24.24.2-4.04.04.03.83.8-3.8-3.8-3.92.93.52.52.2
Bone: post-yield work7.710.412.7-3.43.6-3.6-3.6-3.3-3.23.23.1-3.43.43.33.53.5-3.5-3.6-2.72.82.62.52.4
Progressive ratio test 1 active lever presses1.51.63.51.7-1.81.91.91.51.4-1.4-1.41.2-1.4-1.2-0.9-1.01.01.01.0-1.2-0.4-0.00.0
Progressive ratio test 1 breakpoint1.81.83.81.7-1.81.91.81.51.5-1.5-1.41.2-1.5-1.3-1.1-1.21.21.21.1-1.4-0.6-0.3-0.2
Progressive ratio test 1 inactive lever presses2.22.44.61.6-1.52.01.51.51.5-1.5-1.52.1-1.9-1.7-1.8-1.71.71.61.6-1.3-0.5-0.4-0.3
Progressive ratio test 2 active lever presses1.01.12.41.2-1.21.51.21.01.1-1.0-1.01.4-1.4-1.1-0.9-0.90.90.81.1-0.3-0.10.40.5
Progressive ratio test 2 breakpoint1.21.43.11.4-1.41.81.41.31.3-1.3-1.31.4-1.5-1.2-1.0-1.01.00.91.3-0.4-0.20.20.3
Progressive ratio test 2 inactive lever presses2.32.64.71.8-1.82.11.71.71.7-1.6-1.62.2-2.0-1.7-1.7-1.71.71.61.7-1.3-0.5-0.6-0.5
Incentive Sensitization - Responses0.10.10.3-0.20.30.4-0.3-0.2-0.10.10.10.2-0.2-0.10.00.2-0.2-0.20.40.50.60.50.5
Incentive Sensitization - Breakpoint0.10.10.4-0.00.20.6-0.1-0.00.0-0.0-0.00.4-0.4-0.2-0.10.1-0.1-0.10.50.50.40.50.6
Sum of active levers in priming session hrs 5-60.10.10.50.2-0.10.10.20.10.2-0.2-0.1-0.00.20.20.40.4-0.4-0.4-0.20.70.00.30.4
Progressive ratio0.10.10.3-0.20.00.30.2-0.3-0.30.30.40.2-0.30.10.20.3-0.3-0.3-0.60.30.1-0.1-0.2
Food seeking constrained by brief footshock0.81.02.2-0.50.4-0.7-0.0-0.9-0.90.91.0-1.01.01.00.80.9-0.9-0.9-1.51.41.51.21.1
Seeking ratio, punishment vs. effort0.20.20.7-0.20.2-0.7-0.4-0.2-0.10.10.1-0.80.80.40.30.3-0.3-0.3-0.00.50.50.70.8
Retroperitoneal fat weight0.20.54.70.3-0.40.2-0.00.30.2-0.3-0.3-0.2-0.10.20.10.1-0.1-0.10.1-1.0-0.4-1.9-2.2
Reaction time number correct0.60.81.9-0.91.0-1.4-0.8-1.0-0.91.01.0-1.00.90.60.60.6-0.6-0.7-1.01.30.21.01.0
Reaction time mean minus median8.210.914.93.6-3.53.42.93.73.7-3.8-3.93.0-3.0-2.8-2.6-2.72.72.73.7-3.4-3.0-3.7-3.6
Reaction time mean minus median AUC5.57.210.43.0-2.92.72.33.13.1-3.2-3.22.4-2.5-2.2-2.0-2.02.02.03.1-2.7-2.6-3.0-2.9
Reaction time num false alarms2.22.94.61.6-1.81.52.11.51.3-1.3-1.31.7-1.6-1.9-2.0-2.02.02.00.8-2.0-1.7-1.6-1.6
Reaction time num false alarms AUC3.34.66.92.1-2.42.02.62.01.8-1.8-1.82.1-2.0-2.2-2.3-2.32.32.31.2-2.5-2.1-2.3-2.3
Reaction time trials correct on left0.60.81.9-0.91.0-1.4-0.8-1.0-0.91.01.0-1.00.90.60.60.6-0.6-0.7-1.01.30.21.01.0
Reaction time trials on left0.40.61.5-0.80.8-1.2-0.6-0.8-0.70.80.8-0.90.80.50.50.5-0.5-0.6-0.91.20.10.90.8
Reaction time mean0.50.71.91.0-1.00.80.41.01.1-1.2-1.20.1-0.1-0.10.10.0-0.0-0.01.2-0.7-0.5-1.4-1.4
Reaction time mean AUC0.30.41.40.8-0.70.60.20.70.7-0.8-0.9-0.20.20.10.40.3-0.3-0.30.8-0.3-0.2-1.1-1.2
Median of all reaction times0.20.31.00.00.1-0.2-0.5-0.00.0-0.1-0.1-0.91.00.81.00.9-0.9-0.90.20.30.4-0.3-0.4
Reaction time omissions5.77.812.33.5-3.53.53.23.33.2-3.3-3.32.7-2.8-2.4-2.2-2.22.22.22.7-2.5-1.7-2.3-2.3
Reaction time false alarm rate2.63.75.71.9-2.12.12.31.81.6-1.6-1.61.9-1.8-1.8-1.9-1.91.92.01.2-2.4-1.7-2.2-2.2
Reaction time premature initiation rate1.82.44.22.0-2.01.62.01.71.7-1.7-1.71.4-1.4-1.6-1.7-1.61.61.61.0-0.9-1.2-0.6-0.4
Reaction time premature initiations0.91.32.41.5-1.41.01.51.21.3-1.2-1.20.9-1.0-1.2-1.4-1.31.31.20.7-0.3-1.1-0.1-0.0
Std. dev. reaction times5.57.711.73.2-3.02.92.33.23.2-3.4-3.42.3-2.3-2.2-2.0-2.02.02.13.3-2.8-2.6-3.2-3.1
Reaction time trials completed0.40.61.5-0.80.8-1.2-0.6-0.8-0.70.80.8-0.90.80.50.50.5-0.5-0.6-0.91.20.10.90.8
Reaction time trials AUC0.81.12.4-1.11.1-1.6-0.9-1.2-1.11.21.2-1.21.10.70.70.7-0.7-0.8-1.21.40.41.11.0
Run reversals in cocaine runway, females0.50.51.80.5-0.60.91.20.30.2-0.2-0.11.3-1.2-0.6-0.5-0.50.50.5-0.2-0.20.10.91.0
Run reversals in cocaine runway, males3.33.212.71.3-1.41.00.81.51.3-1.4-1.51.1-1.1-1.3-1.1-1.11.11.11.6-2.8-2.5-3.6-3.6
Latency to leave start box in cocaine runway0.20.21.70.2-0.00.1-0.10.30.4-0.4-0.40.3-0.2-0.4-0.4-0.30.30.30.6-0.4-1.3-0.6-0.5
Latency to leave start box in cocaine runway, F1.81.93.21.4-1.41.41.41.41.4-1.4-1.41.5-1.5-1.5-1.4-1.31.31.31.3-1.3-1.8-1.1-1.0
Latency to leave start box in cocaine runway, M1.81.72.7-1.51.6-1.6-1.6-1.4-1.31.31.3-1.61.61.41.21.2-1.2-1.2-1.21.20.50.90.8
Std. dev. time between licks in bursts0.40.41.01.0-1.00.50.90.90.9-0.9-0.90.5-0.5-0.5-0.3-0.30.30.40.5-0.4-0.8-0.2-0.1
Total sessions with >9 infusions0.40.41.20.6-0.90.91.10.50.3-0.4-0.30.7-0.7-0.6-0.7-0.70.70.60.0-1.10.80.20.2
Short access day 1 total inactive lever presses0.30.31.00.7-0.90.41.00.50.3-0.4-0.30.9-0.5-0.3-0.6-0.50.50.4-0.0-0.60.6-0.2-0.3
Short access day 10 total inactive lever presses0.30.32.10.3-0.30.20.60.10.2-0.1-0.10.5-0.3-0.2-0.4-0.20.20.1-0.30.30.71.41.4
Short access day 1 total infusions0.10.10.4-0.0-0.10.50.2-0.0-0.20.10.10.4-0.2-0.1-0.2-0.10.10.0-0.1-0.60.2-0.4-0.5
Short access day 10 total infusions1.61.84.81.0-1.21.00.81.21.0-1.1-1.11.2-1.2-1.3-1.6-1.51.51.41.3-2.2-0.7-1.9-1.9
Short access total infusions0.20.20.60.4-0.50.60.60.40.2-0.3-0.20.7-0.5-0.4-0.7-0.60.60.50.2-0.80.4-0.4-0.5
Short access day 1 locomotion0.90.92.20.4-0.30.50.20.70.6-0.7-0.70.7-0.8-1.0-1.2-1.21.21.21.0-1.5-1.3-1.4-1.3
Short access day 10 total locomotion0.70.81.80.6-0.50.40.30.80.8-0.8-0.80.0-0.6-0.9-1.3-1.31.31.21.0-1.3-1.1-0.7-0.6
Short access total locomotion0.90.93.30.6-0.70.40.50.80.7-0.7-0.70.2-0.6-0.9-1.3-1.31.31.30.8-1.8-1.0-1.1-1.1
One hour access (0.3 mA shock)0.30.41.10.5-0.50.90.20.50.4-0.5-0.51.1-0.7-0.4-0.3-0.30.30.20.9-0.40.6-0.9-1.0
Compulsive drug intake0.40.40.6-0.70.8-0.5-0.8-0.7-0.70.70.7-0.50.60.60.60.6-0.6-0.7-0.50.80.60.60.6
One hour access (shock baseline)0.10.10.70.2-0.10.5-0.10.20.1-0.2-0.20.8-0.4-0.1-0.1-0.00.0-0.00.6-0.10.7-0.4-0.5
Social response proportion1.11.23.30.9-1.01.61.10.90.8-0.8-0.81.7-1.8-1.7-1.0-1.01.00.90.9-0.8-0.4-0.6-0.5
Social responses7.910.215.93.4-3.43.93.53.33.2-3.2-3.23.9-4.0-3.5-3.3-3.33.33.23.0-2.6-2.3-1.8-1.6
Social time1.72.25.41.4-1.21.80.61.61.6-1.7-1.71.3-1.4-1.3-1.1-1.21.21.22.3-1.4-1.4-1.7-1.7
Soleus weight0.92.63.8-1.81.8-2.0-1.9-1.6-1.61.61.6-2.02.01.81.71.7-1.7-1.8-1.41.20.80.50.5
Bone: stiffness11.317.923.0-4.84.8-4.5-4.8-4.6-4.64.54.5-4.44.44.44.54.5-4.5-4.5-3.93.73.42.11.8
Tibialis anterior weight1.96.48.9-3.03.0-2.8-3.0-2.8-2.82.82.8-2.72.72.62.62.6-2.6-2.6-2.32.21.71.00.8
Time to tail flick, vehicle, before self-admin0.40.41.20.9-1.01.11.00.70.6-0.7-0.70.5-0.5-0.4-0.1-0.20.20.00.3-0.80.3-0.6-0.7
Time to tail flick, vehicle, after self-admin0.10.10.40.10.10.40.10.10.1-0.1-0.10.3-0.0-0.1-0.1-0.00.00.10.20.60.10.50.6
Time to tail flick, test, before self-admin1.11.13.00.9-1.01.41.30.80.6-0.7-0.71.7-1.5-1.1-1.0-1.11.11.20.7-1.2-0.4-0.9-1.0
Time to tail flick, test, after self-admin0.20.20.7-0.20.50.0-0.50.10.2-0.2-0.20.4-0.4-0.3-0.2-0.30.30.20.80.4-0.40.70.8
Delta time to tail flick, vehicle, before/after SA0.40.42.4-0.50.6-0.4-0.6-0.5-0.40.40.4-0.30.50.50.40.6-0.6-0.4-0.21.60.51.01.1
Delta time to tail flick, test, before/after SA0.30.31.4-0.50.8-0.7-1.2-0.10.1-0.1-0.1-0.80.40.10.10.1-0.1-0.20.70.5-0.60.50.7
Tibia length6.418.022.0-4.34.2-3.9-3.4-4.5-4.54.54.6-3.93.94.24.14.1-4.1-4.1-4.74.54.34.64.4
Ambulatory time before self-admin2.42.55.81.8-1.92.22.41.51.5-1.4-1.31.7-1.6-1.7-1.7-1.81.81.80.8-0.9-0.40.40.5
Ambulatory time after self-admin0.50.52.20.7-0.90.11.30.20.2-0.2-0.10.1-0.00.20.10.1-0.10.0-0.80.61.51.41.3
Bone: tissue strength0.30.30.8-0.60.7-0.5-0.9-0.5-0.40.40.4-0.60.60.50.70.7-0.7-0.8-0.10.80.20.10.1
Total heroin consumption3.44.06.5-1.91.9-2.1-1.6-2.0-1.92.02.0-2.12.11.91.61.7-1.7-1.7-2.12.32.32.52.5
Bone: trabecular number3.25.06.9-2.42.2-2.3-2.2-2.4-2.62.52.5-2.22.22.32.42.4-2.4-2.4-2.31.42.50.40.0
Bone: trabecular spacing0.81.01.71.0-0.81.00.91.11.3-1.2-1.20.8-0.8-0.9-1.0-1.01.01.01.10.2-1.30.81.2
Bone: trabecular thickness0.80.92.60.8-1.00.90.90.80.6-0.7-0.71.0-1.0-0.8-0.9-0.90.90.90.6-1.50.0-1.4-1.6
Bone: trabecular tissue density0.40.62.60.5-0.40.40.00.60.7-0.7-0.70.3-0.3-0.5-0.4-0.40.40.40.9-1.1-1.6-1.3-1.2
Water consumed over 24 hours0.20.20.8-0.40.5-0.5-0.9-0.3-0.20.20.1-0.60.60.40.50.4-0.4-0.50.30.1-0.6-0.7-0.7
Number of responses in last shaping day0.50.51.9-0.30.2-0.1-0.50.1-0.0-0.0-0.10.1-0.3-0.5-0.9-0.90.90.90.6-1.3-0.6-1.3-1.4