Hub : Genes

Pced1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_063263663.1 0.07 0.1 2.5e-03 0.02 0.02 0.02 0.02 1.4e-03 1.1e-03 1.9e-03 1.4e-03
2 pVTA gene expression Pced1b 0.07 0.05 1.7e-05 0.07 0.06 0.05 0.05 3.4e-06 1.4e-05 1.0e-04 5.1e-05
3 Adipose alternative TSS XM_008765742.4 0.03 0.03 3.2e-04 0.02 0.03 0.02 0.02 1.6e-03 5.9e-04 2.0e-03 2.5e-03
4 Adipose mRNA stability Pced1b 0.1 0.06 0.0e+00 0.14 0.14 0.14 0.14 7.7e-15 3.6e-15 4.7e-15 3.9e-15
5 Adipose alternative TSS XM_008765737.3 0.02 0.02 5.6e-03 0.01 0.01 -0 0.01 1.1e-02 1.0e-02 4.6e-01 2.2e-02
6 Adipose intron excision ratio chr7_130384263_130405718 0.05 0.04 5.5e-07 0.04 0.05 0.04 0.04 9.6e-06 4.7e-06 8.1e-06 1.3e-05
7 Brain mRNA stability Pced1b 0.19 0.15 1.8e-07 0.05 0.04 0.05 0.06 1.9e-05 1.2e-04 8.9e-06 6.6e-06
8 pVTA alternative polyA XM_008765740.4 0.24 0.11 4.8e-04 0.03 0.04 0.04 0.02 2.1e-03 4.2e-04 1.5e-04 1.0e-02
9 NAcc alternative TSS XM_008765737.3 0.04 0.03 3.1e-03 0.02 0.02 0.02 0.02 1.6e-03 1.4e-03 5.0e-04 8.3e-04
10 NAcc gene expression Pced1b 0.08 0.05 4.3e-10 0.06 0.06 0.07 0.06 2.6e-09 4.7e-10 1.9e-10 6.9e-10
11 Adipose gene expression Pced1b 0.1 0.1 8.4e-04 0.03 0.02 0.03 0.03 3.2e-04 1.2e-03 1.3e-04 5.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density6.010.313.1-2.8-3.33.53.5-3.5-3.63.1-3.5-3.1-3.60.9
Area under the delay curve1.01.12.6-1.4-1.20.91.0-1.0-1.00.5-1.6-0.6-0.81.1
BMI with tail5.218.026.0-5.1-4.94.34.4-4.4-4.43.9-4.9-3.2-4.12.5
BMI without tail1.75.29.0-3.0-2.92.22.3-2.2-2.22.0-3.0-1.4-1.81.4
Body weight5.122.435.9-6.0-5.54.95.0-5.0-4.94.4-5.2-3.4-4.13.1
Weight adjusted by age1.11.65.5-2.3-1.31.41.4-1.4-1.30.7-1.2-0.4-0.60.9
Bone surface8.014.516.9-3.9-4.14.04.1-4.0-4.03.8-4.0-3.7-4.01.6
Bone volume5.29.311.4-3.2-3.23.23.3-3.2-3.32.9-3.3-2.9-3.40.8
Breakpoint value in progressive ratio session1.82.23.3-0.4-1.51.61.6-1.6-1.61.7-1.3-1.8-1.70.7
Number of licking bursts0.20.31.30.50.5-0.4-0.50.40.5-0.21.10.31.00.2
Context. condit. distance diff. score0.50.60.8-0.8-0.80.70.8-0.7-0.70.9-0.8-0.8-0.9-0.5
Locomotion velocity, session 10.70.82.20.30.6-0.8-0.80.80.9-1.01.01.11.50.2
Locomotion distance, session 12.93.66.41.81.9-1.9-1.91.91.8-2.51.42.41.7-1.6
Locomotion velocity, session 20.20.20.60.40.2-0.5-0.50.40.4-0.8-0.10.70.40.5
Locomotion distance, session 22.12.95.11.61.4-1.8-1.71.71.6-2.30.92.21.5-1.4
Locomotion velocity, session 32.73.14.31.71.7-1.9-1.91.91.8-2.11.32.01.8-0.8
Locomotion distance, session 34.14.47.22.72.0-2.1-2.12.12.0-2.31.72.41.9-1.7
Stereotopy head waving bouts, day 30.50.61.5-1.2-0.90.60.7-0.6-0.60.7-0.9-0.7-0.60.8
Stereotopy head waving duration, day 30.20.31.0-1.0-0.60.30.3-0.3-0.20.4-0.6-0.4-0.20.7
Locomotion velocity, session 70.00.10.20.2-0.1-0.1-0.10.10.1-0.20.30.30.4-0.3
Locomotion distance, session 71.41.82.41.11.1-1.2-1.21.21.2-1.41.51.51.5-1.5
Stereotopy head waving bouts, day 71.61.82.8-0.9-1.51.41.4-1.4-1.41.7-1.1-1.5-1.20.8
Stereotopy head waving duration, day 72.12.54.0-1.0-1.71.71.6-1.6-1.62.0-1.3-1.9-1.41.4
Locomotion velocity, session 80.30.30.7-0.6-0.80.50.5-0.5-0.40.6-0.8-0.5-0.40.8
Locomotion distance, session 80.71.02.21.10.7-1.1-1.01.00.9-1.20.11.20.5-1.5
Degree of sensitization distance0.40.41.9-1.4-0.60.60.6-0.5-0.40.6-0.1-0.6-0.20.4
Degree of sensitization stereotypy1.01.12.4-0.4-1.11.11.0-1.1-1.01.5-0.6-1.4-0.80.9
Conditioned locomotion0.30.40.9-0.40.2-0.5-0.50.50.6-0.50.60.70.90.8
Cocaine response after cond. corrected0.30.31.2-1.1-0.2-0.3-0.10.20.2-0.7-0.70.5-0.20.9
Cocaine response after cond. not corrected1.01.22.60.11.1-1.3-1.21.31.2-1.60.51.30.90.6
Cocaine response before conditioning5.26.211.53.42.8-2.5-2.62.52.5-1.92.91.82.4-1.3
Saline control response0.10.10.30.40.3-0.5-0.40.40.4-0.20.00.20.20.6
Bone: connectivity density4.57.08.6-2.4-2.72.82.8-2.8-2.92.6-2.8-2.6-2.91.5
Bone: cortical apparent density0.60.81.3-0.00.6-1.2-1.11.11.2-1.00.31.11.00.5
Bone: cortical area9.013.817.0-3.5-3.84.14.1-4.1-4.13.6-3.9-3.5-4.01.5
Bone: cortical porosity1.92.13.31.51.8-1.6-1.61.61.6-1.31.61.31.3-0.4
Bone: cortical porosity1.61.82.71.61.7-1.5-1.51.51.5-1.01.41.01.0-0.5
Bone: cortical thickness4.06.68.9-2.2-2.62.72.8-2.8-2.92.3-3.0-2.3-2.91.5
Bone: cortical thickness0.30.30.7-0.3-0.20.50.6-0.6-0.7-0.2-0.90.2-0.8-0.9
Bone: cortical tissue density0.71.01.60.00.7-1.2-1.21.21.2-1.10.41.21.10.4
Condit. Reinf. active minus inactive responses0.20.30.70.00.2-0.5-0.50.50.5-0.60.10.80.4-0.8
Condit. Reinf. active-inactive response ratio0.10.10.2-0.3-0.30.30.3-0.3-0.30.1-0.40.1-0.4-0.3
Condit. Reinf. active responses1.01.23.50.60.7-1.1-1.01.01.0-1.20.61.40.9-1.9
Condit. Reinf. inactive responses3.34.05.11.41.9-2.1-2.02.12.1-2.21.92.12.0-2.3
Incentive salience index mean0.10.10.2-0.4-0.3-0.1-0.00.10.1-0.1-0.40.3-0.1-0.5
Condit. Reinf. lever presses0.20.20.9-0.9-0.70.20.3-0.2-0.20.2-0.8-0.2-0.40.3
Condit. Reinf. active minus inactive responses0.00.10.1-0.00.2-0.2-0.20.20.2-0.30.20.30.3-0.1
Condit. Reinf. active-inactive response ratio0.60.71.90.60.7-0.5-0.50.50.5-1.10.81.10.8-1.4
Condit. Reinf. active responses0.30.40.60.20.5-0.7-0.70.70.8-0.60.60.60.8-0.2
Condit. Reinf. inactive responses0.71.01.70.60.9-1.2-1.21.21.3-0.61.10.71.20.1
Condit. Reinf. lever presses0.10.20.40.4-0.30.30.3-0.3-0.40.4-0.6-0.6-0.60.2
Condit. Reinf. lever reinforcers received0.40.60.80.60.7-0.9-0.90.90.9-0.70.70.70.8-0.5
Conditioned reinforcement - actives0.20.30.90.70.3-0.7-0.60.70.6-0.4-0.00.40.0-0.9
Conditioned reinforcement - inactives1.72.54.42.01.9-1.6-1.61.61.5-1.41.21.01.0-2.1
Conditioned locomotion0.10.10.60.1-0.4-0.2-0.10.20.20.3-0.7-0.2-0.40.1
Patch foraging indifference point 0 sec0.91.75.22.31.6-1.0-1.11.00.9-1.01.61.01.0-1.4
Patch foraging indifference point AUC0.40.51.51.10.6-0.6-0.60.60.6-0.60.30.60.4-1.2
Delay disc. indifference point, 0s delay1.01.12.2-1.5-1.41.11.1-1.1-1.10.6-1.3-0.4-0.51.1
Delay disc. indifference point, 16s delay1.21.32.2-1.5-1.21.01.1-1.0-1.01.0-1.3-1.0-0.91.3
Delay disc. indifference point, 2s delay0.50.52.1-1.4-1.00.50.6-0.6-0.50.2-1.2-0.1-0.10.3
Delay disc. indifference point, 24s delay0.91.02.1-1.2-1.01.01.0-1.0-0.90.9-0.8-0.9-0.61.5
Delay disc. indifference point, 4s delay0.40.41.5-1.2-0.80.40.5-0.4-0.40.2-1.1-0.2-0.4-0.1
Delay disc. indifference point, 8s delay2.53.05.7-1.9-2.11.71.8-1.7-1.71.2-2.4-1.1-1.51.3
Indifference point function ln k1.62.85.5-2.3-1.91.91.8-1.8-1.71.5-1.4-1.0-1.01.6
Indifference point function log k1.62.85.5-2.3-1.91.91.8-1.8-1.71.5-1.4-1.0-1.01.6
Patch foraging total patch changes 0 sec0.91.75.22.31.5-1.0-1.11.00.9-0.91.51.00.9-1.3
Patch foraging total patch changes 12 sec0.70.94.72.21.1-0.7-0.70.70.6-0.31.00.10.3-1.2
Patch foraging total patch changes 18 sec1.92.96.72.62.0-1.5-1.61.51.5-0.92.20.61.4-2.1
Patch foraging total patch changes 24 sec0.61.02.21.21.1-0.9-1.01.01.1-0.31.50.21.0-1.0
Patch foraging total patch changes 6 sec1.92.86.72.62.0-1.5-1.51.51.4-1.51.71.41.4-1.8
Patch foraging time to switch 0 sec2.04.05.21.92.2-2.3-2.22.32.3-1.82.11.51.8-1.2
Patch foraging water rate 0 sec3.57.48.8-2.3-2.93.02.9-3.0-3.02.8-2.9-2.4-2.71.7
Patch foraging water rate 12 sec2.24.66.2-2.3-2.52.32.2-2.2-2.12.2-2.2-1.7-1.72.1
Patch foraging water rate 18 sec0.71.23.6-1.4-1.21.00.9-1.0-0.90.8-1.0-0.4-0.61.9
Patch foraging water rate 24 sec4.15.87.6-1.4-2.82.62.6-2.6-2.62.7-2.4-2.4-2.51.3
Patch foraging water rate 6 sec5.07.310.4-2.3-3.23.03.0-3.0-3.02.8-2.8-2.4-2.41.4
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.5-0.40.10.2-0.1-0.20.2-0.5-0.3-0.0-0.2
Distance traveled before self-admin0.30.51.91.40.7-0.4-0.40.40.3-0.30.7-0.00.2-1.2
Distance traveled after self-admin0.50.61.61.2-0.30.30.4-0.4-0.50.8-0.8-1.0-1.3-0.6
Extensor digitorum longus weight5.321.025.1-5.0-4.84.84.9-4.8-4.84.4-4.7-4.3-4.43.4
Bone: elastic displacement3.54.18.22.92.2-1.9-1.91.91.8-1.72.11.61.5-2.3
Bone: elastic work0.10.20.70.80.30.00.0-0.0-0.10.1-0.1-0.3-0.5-0.8
Bone: endosteal estimation6.414.116.9-3.9-4.14.14.1-4.1-4.04.1-3.3-3.9-3.71.1
Bone: endosteal perimeter6.012.815.5-3.6-3.83.93.9-3.9-3.93.8-3.3-3.7-3.60.8
Epididymis fat weight1.65.48.0-2.8-2.82.02.1-2.0-1.92.7-2.6-2.1-1.92.3
Delta time in closed arm before/after self-admin0.10.10.10.10.1-0.3-0.30.30.30.20.40.10.2-0.2
Delta time in open arm before/after self-admin0.70.71.20.91.0-0.8-0.80.70.7-1.10.70.80.6-0.7
Diff in mean of infusions in LGA sessions0.30.30.8-0.9-0.50.60.7-0.6-0.70.3-0.70.0-0.30.2
Delay discount exponential model param0.80.92.31.31.1-0.9-0.90.90.9-0.51.50.50.8-0.8
Extinction: sum of active levers before priming1.61.72.9-0.8-1.11.51.5-1.5-1.51.4-0.8-1.7-1.40.1
Active lever presses in extinction session 61.41.42.1-0.4-1.51.41.4-1.4-1.51.1-1.1-0.9-1.0-0.7
Bone: final force8.513.615.7-3.8-3.83.94.0-3.9-3.93.6-3.8-3.6-3.82.0
Bone: final moment8.814.116.3-3.9-3.94.04.0-4.0-4.03.7-3.8-3.7-3.92.0
Food consumed during 24 hour testing period1.01.42.4-1.2-1.21.11.2-1.1-1.21.1-1.5-1.0-1.40.1
Glucose0.10.21.2-1.1-0.50.20.2-0.2-0.10.2-0.4-0.10.10.8
Heart weight0.20.31.8-1.3-0.70.00.0-0.00.10.1-0.60.30.40.4
Delay discount hyperbolic model param0.70.82.21.41.0-0.7-0.80.80.8-0.31.50.40.7-0.8
Intermittent access intake day 1-15 change0.10.20.7-0.4-0.0-0.3-0.30.30.3-0.4-0.40.50.50.8
Intermittent access intake escalation0.10.20.9-0.7-0.20.00.1-0.0-0.0-0.2-0.60.20.10.9
Intermittent access intake escalation 20.10.10.40.1-0.00.10.2-0.2-0.20.0-0.7-0.4-0.6-0.1
Intermitt. access day 1 inactive lever presses0.52.14.31.31.7-1.3-1.41.41.4-1.02.10.91.4-1.5
Intermitt. access day 15 inactive lever presses0.91.82.90.91.5-1.3-1.31.31.2-1.41.21.61.1-1.7
Intermitt. access escalation Index0.71.02.90.2-0.41.11.0-1.1-1.11.20.3-1.7-0.9-1.1
Intermittent access day 1 total infusions1.01.64.01.21.3-1.1-1.11.11.0-1.41.11.50.7-2.0
Intermittent access day 15 total infusions0.40.71.20.41.0-0.8-0.80.80.8-1.10.71.10.7-0.6
Intermittent access terminal intake (last 3 days)0.91.11.60.61.2-1.2-1.21.21.2-1.30.91.31.1-0.3
Intermittent access total infusions0.91.11.71.21.2-1.0-1.01.00.9-1.10.91.10.7-1.3
Intermittent access day 1 locomotion0.10.10.4-0.10.3-0.3-0.40.30.4-0.10.60.30.4-0.1
Intermittent access day 15 total locomotion0.00.10.1-0.20.3-0.2-0.30.30.3-0.20.30.20.40.0
Intermittent access total locomotion0.20.30.50.30.6-0.6-0.70.70.7-0.40.50.30.4-0.1
Intermittent access standard deviation0.20.51.00.10.7-0.7-0.70.70.7-1.00.21.00.2-0.9
Left kidney weight0.73.56.2-2.5-1.91.92.0-1.9-2.01.3-2.5-1.0-2.0-0.2
Right kidney weight3.214.424.0-4.9-4.04.14.2-4.2-4.23.4-3.9-3.0-3.61.3
Cocaine induced anxiety2.94.15.8-2.1-2.42.02.0-2.0-1.92.4-1.9-2.0-1.81.5
Post-drug Anxiety4.95.27.3-1.8-2.52.22.2-2.2-2.22.7-2.6-2.6-2.41.6
Baseline Anxiety0.20.20.60.0-0.30.40.5-0.4-0.60.3-0.7-0.6-0.8-0.1
Tail length0.10.31.1-1.0-0.50.0-0.0-0.00.10.2-0.40.40.81.0
Length with tail1.25.28.8-3.0-2.62.52.4-2.5-2.42.0-2.3-1.3-1.61.9
Length without tail5.216.720.2-4.5-4.44.44.5-4.4-4.43.9-4.1-3.3-3.92.6
Times rat made contact with spout0.10.10.2-0.4-0.40.30.4-0.3-0.40.3-0.4-0.4-0.50.2
Lifetime Intake1.01.23.31.41.2-0.9-0.90.90.9-1.10.81.10.6-1.8
Liver weight, left6.310.512.7-3.6-3.53.43.4-3.4-3.33.4-3.2-3.4-3.21.2
Liver weight, right2.23.95.7-1.6-1.82.32.3-2.3-2.41.8-1.7-1.9-2.3-0.3
Locomotor activity0.81.31.71.21.2-1.2-1.21.21.2-1.11.31.01.0-1.1
Locomotor testing distance1.93.56.02.32.2-1.7-1.81.81.7-1.62.51.21.5-2.0
Locomotor testing rearing1.93.97.02.72.4-1.6-1.71.61.6-1.62.61.21.5-2.5
Locomotion in novel chamber1.21.62.2-1.3-1.51.41.4-1.4-1.51.0-1.2-1.0-1.10.7
Locomotion in novel chamber post-restriction0.30.63.0-0.9-1.10.40.4-0.4-0.30.5-0.7-0.3-0.01.7
Fecal boli incidents, locomotor time 10.30.41.00.60.4-0.9-0.80.80.7-0.8-0.51.00.20.1
Change in fecal boli incidents, locomotor task0.20.20.8-0.6-0.00.50.3-0.4-0.30.30.9-0.40.60.3
Time >=10cm from walls, locomotor time 10.80.92.3-0.1-1.20.91.0-1.0-1.10.7-1.5-0.6-1.10.1
Bouts of movement, locomotor time 10.40.54.3-0.6-0.20.20.3-0.3-0.30.1-0.3-0.2-0.42.1
Total resting periods, locomotor time 10.20.21.9-0.10.3-0.3-0.30.30.2-0.40.20.30.01.4
Rest time, locomotor task time 10.10.10.50.40.4-0.2-0.20.20.1-0.20.70.10.20.7
Distance moved, locomotor task time 10.30.43.40.9-0.1-0.0-0.0-0.0-0.1-0.1-0.40.0-0.3-1.9
Vertical activity count, locomotor time 10.71.62.9-0.6-1.21.21.3-1.3-1.40.8-1.7-0.9-1.7-1.1
Time >=10cm from walls, locomotor time 20.20.31.51.10.4-0.2-0.20.20.1-0.20.2-0.1-0.3-1.2
Bouts of movement, locomotor time 22.13.34.2-2.0-2.02.01.9-1.9-1.91.9-1.4-2.0-1.71.1
Total resting periods, locomotor time 21.83.24.8-2.2-2.01.91.9-1.9-1.81.8-1.4-1.8-1.51.4
Rest time, locomotor task time 20.40.43.9-0.7-0.10.10.1-0.10.00.30.4-0.00.52.0
Distance moved, locomotor task time 20.70.85.61.50.4-0.1-0.10.1-0.1-0.3-0.1-0.2-0.9-2.4
Vertical activity count, locomotor time 20.40.61.7-0.1-0.50.80.8-0.8-0.80.7-0.6-1.1-1.3-0.5
Light reinforcement 11.63.95.12.12.1-2.1-2.22.12.2-1.62.21.72.2-0.2
Light reinforcement 21.32.03.40.11.3-1.5-1.51.51.6-1.41.41.61.91.1
Bone: marrow area6.514.217.1-3.9-4.14.14.1-4.1-4.04.1-3.3-3.9-3.71.1
Bone: maximum diameter4.17.79.8-2.8-2.83.13.1-3.1-3.12.8-2.4-2.8-2.81.0
Bone: maximum force10.618.821.9-4.5-4.54.64.7-4.6-4.64.3-4.3-4.2-4.32.5
Bone: maximum moment10.818.922.0-4.6-4.54.64.7-4.7-4.64.3-4.3-4.2-4.42.3
Mean time between licks in bursts0.40.91.30.50.8-1.1-1.11.11.2-0.80.80.91.10.6
Mean num. licks in bursts0.20.31.1-0.2-0.20.10.3-0.2-0.4-0.0-1.1-0.1-1.0-0.6
Cd content in liver1.82.03.80.31.2-1.4-1.41.41.4-1.61.32.01.9-0.7
Co content in liver0.20.21.30.30.2-0.4-0.20.30.2-0.7-0.30.6-0.1-1.2
Cu content in liver2.52.93.9-1.0-1.72.01.9-2.0-2.01.9-1.5-1.9-1.8-0.1
Fe content in liver1.11.42.51.31.1-1.1-1.21.21.2-0.91.60.81.2-1.2
K content in liver0.70.61.0-1.0-0.90.90.9-0.9-1.00.4-0.9-0.4-0.7-0.0
Mg content in liver0.10.10.80.30.00.20.2-0.2-0.3-0.3-0.00.30.1-0.9
Mn content in liver0.10.10.3-0.60.00.00.0-0.00.0-0.10.20.00.30.5
Na content in liver0.30.30.7-0.0-0.40.70.6-0.6-0.60.80.2-0.7-0.2-0.6
Rb content in liver0.10.20.4-0.1-0.20.60.5-0.5-0.50.50.3-0.6-0.0-0.1
Se content in liver0.80.91.40.50.7-1.0-1.01.01.0-1.10.61.21.1-1.2
Sr content in liver2.11.82.3-1.2-1.41.41.4-1.4-1.41.4-1.4-1.3-1.50.6
Zn content in liver0.30.31.70.60.4-0.2-0.20.20.1-0.50.50.50.5-1.3
Bone: minimum diameter6.812.315.2-3.4-3.73.93.9-3.9-3.93.5-3.4-3.4-3.61.2
Time in familiar zone, hab. session 10.40.31.90.30.4-0.4-0.30.40.3-0.80.10.70.1-1.4
Time in novel zone, hab. session 10.30.31.7-0.3-0.30.20.1-0.2-0.10.80.3-0.70.21.3
Total zone transitions, hab. session 10.30.40.60.40.2-0.7-0.70.70.7-0.80.20.80.8-0.3
Total locomotion distance, hab. session 10.10.10.40.1-0.2-0.3-0.20.20.2-0.5-0.40.60.1-0.6
Locomotion velocity, hab. session 10.10.10.30.1-0.3-0.1-0.10.10.0-0.4-0.40.50.1-0.5
Time in familiar zone, hab. session 20.10.10.6-0.0-0.00.10.2-0.1-0.20.0-0.10.0-0.2-0.8
Time in novel zone, hab. session 20.10.10.8-0.20.0-0.2-0.30.20.30.20.3-0.20.40.9
Total zone transitions, hab. session 20.20.20.70.20.1-0.4-0.30.30.3-0.8-0.10.80.3-0.7
Total locomotion distance, hab. session 20.30.41.40.50.4-0.5-0.40.40.3-1.00.21.20.4-1.1
Locomotion velocity, hab. session 20.20.21.00.30.1-0.2-0.20.20.1-0.8-0.11.00.2-0.8
Novel to familiar place preference ratio0.70.71.8-1.0-0.70.90.8-0.9-0.80.9-0.2-0.8-0.41.3
Novelty place preference0.30.31.2-0.8-0.40.60.5-0.5-0.50.70.0-0.6-0.11.1
Time in novel zone, NPP test0.20.20.8-0.7-0.30.50.4-0.4-0.30.60.2-0.5-0.00.9
Total zone transitions, NPP test0.91.32.81.10.8-1.2-1.11.21.1-1.70.31.60.9-0.9
Total locomotion distance, NPP test2.53.56.21.81.6-1.9-1.91.81.7-2.41.12.51.7-1.6
Locomotion velocity, NPP test1.52.14.71.41.1-1.4-1.41.41.3-2.10.72.21.3-1.1
Intraocular pressure6.79.716.94.13.1-3.4-3.33.43.3-2.82.52.62.3-3.0
Delta distance traveled before/after self-admin0.20.20.50.1-0.40.30.3-0.3-0.30.5-0.7-0.2-0.50.5
Delta ambulatory time before/after self-admin0.10.20.40.1-0.50.20.2-0.2-0.20.6-0.7-0.3-0.40.6
Parametrial fat weight0.10.21.31.2-0.0-0.5-0.50.50.4-0.2-0.20.3-0.1-0.4
Pavlov. Cond. lever latency0.10.20.80.1-0.10.50.4-0.4-0.40.30.3-0.20.0-0.9
Pavlov. Cond. magazine entry latency0.10.10.20.40.3-0.3-0.20.30.2-0.3-0.10.1-0.3-0.4
Pavlov. Cond. change in total contacts0.10.10.3-0.5-0.1-0.3-0.30.30.3-0.1-0.10.20.20.5
Pavlov. Cond. index score0.20.20.5-0.4-0.40.20.3-0.2-0.20.4-0.6-0.5-0.60.7
Pavlov. Cond. latency score0.10.10.5-0.3-0.30.00.1-0.1-0.10.2-0.6-0.4-0.50.7
Pavlov. Cond. lever contacts0.40.40.80.20.4-0.9-0.80.90.9-0.60.20.50.60.7
Pavlov. Cond. magazine entry number0.00.10.3-0.10.1-0.0-0.10.00.1-0.10.40.20.60.1
Pavlov. Cond. intertrial magazine entries0.60.81.30.40.7-0.9-0.90.90.9-1.00.61.10.9-1.1
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.6-0.60.60.6-0.6-0.60.7-0.8-0.9-0.90.8
Pavlov. Cond. response bias0.10.10.20.30.3-0.5-0.40.40.4-0.3-0.10.2-0.10.2
Pavlov. Cond. lever latency0.10.10.9-0.9-0.10.20.2-0.2-0.10.10.30.10.20.1
Pavlov. Cond. magazine entry latency0.10.20.3-0.1-0.30.50.5-0.5-0.60.2-0.5-0.3-0.5-0.3
Pavlov. Cond. change in total contacts0.81.31.9-0.8-1.21.21.2-1.2-1.21.0-1.4-1.2-1.20.5
Pavlov. Cond. index score0.30.51.00.1-0.60.70.7-0.7-0.80.5-1.0-0.6-0.9-0.1
Pavlov. Cond. latency score0.30.40.80.2-0.60.70.7-0.7-0.80.5-0.9-0.6-0.90.1
Pavlov. Cond. lever contacts0.10.10.80.9-0.00.00.0-0.0-0.1-0.0-0.4-0.2-0.4-0.4
Pavlov. Cond. magazine entry number0.91.21.50.91.1-1.2-1.21.21.2-0.91.11.11.0-0.5
Pavlov. Cond. intertrial magazine entries1.92.84.12.01.7-1.9-1.91.91.8-1.51.51.61.3-1.2
Pavlov. Cond. lever-magazine prob. diff.0.50.61.20.0-0.80.80.8-0.9-1.00.6-1.1-0.7-1.00.1
Pavlov. Cond. response bias0.10.10.30.5-0.10.10.1-0.2-0.20.1-0.5-0.2-0.4-0.4
Time in closed arm before self-admin0.71.02.7-1.6-1.01.01.0-1.0-1.00.2-1.00.2-0.21.3
Time in closed arm after self-admin0.10.20.6-0.10.3-0.0-0.10.00.1-0.30.70.60.8-0.1
Time in open arm before self-admin0.20.20.7-0.2-0.0-0.0-0.10.10.30.70.9-0.40.60.1
Time in open arm after self-admin0.10.10.2-0.30.2-0.3-0.30.30.4-0.00.5-0.10.30.2
Bone: periosteal estimation10.622.426.9-4.7-5.05.25.2-5.2-5.14.9-4.5-4.7-4.81.6
Bone: periosteal perimeter9.716.821.0-4.0-4.24.54.6-4.5-4.63.9-4.1-3.9-4.41.0
Bone: post-yield work7.711.313.7-3.7-3.43.53.5-3.5-3.43.5-3.0-3.5-3.22.8
Progressive ratio test 1 active lever presses2.32.94.92.21.6-1.7-1.71.71.6-1.61.41.61.2-2.1
Progressive ratio test 1 breakpoint2.02.44.42.11.5-1.5-1.61.51.5-1.51.31.51.1-1.9
Progressive ratio test 1 inactive lever presses1.42.06.01.11.5-1.1-1.11.11.1-1.41.71.31.1-2.4
Progressive ratio test 2 active lever presses0.91.01.91.11.1-0.9-0.90.90.9-0.71.30.70.9-1.4
Progressive ratio test 2 breakpoint0.91.01.91.01.2-0.9-0.90.90.9-0.71.40.60.9-1.3
Progressive ratio test 2 inactive lever presses1.01.64.71.41.3-1.0-1.11.01.0-1.01.31.01.0-2.2
Incentive Sensitization - Responses0.10.20.3-0.50.00.60.5-0.5-0.50.40.5-0.5-0.1-0.5
Incentive Sensitization - Breakpoint0.10.20.5-0.30.20.40.4-0.4-0.40.40.7-0.50.0-0.6
Sum of active levers in priming session hrs 5-60.10.10.30.30.3-0.1-0.10.10.20.10.4-0.50.10.1
Progressive ratio0.10.10.60.80.3-0.0-0.10.0-0.0-0.30.10.10.4-0.1
Food seeking constrained by brief footshock0.40.51.21.1-0.30.50.5-0.5-0.60.8-0.7-0.9-1.10.3
Seeking ratio, punishment vs. effort0.10.10.3-0.2-0.30.10.1-0.1-0.00.6-0.1-0.5-0.60.4
Retroperitoneal fat weight0.10.31.2-0.6-0.2-0.6-0.60.60.70.1-0.20.40.51.1
Reaction time number correct0.51.02.2-0.7-1.11.00.9-0.9-0.91.5-1.0-0.9-0.91.2
Reaction time mean minus median4.711.715.22.83.9-3.9-3.73.83.7-3.73.13.12.7-3.1
Reaction time mean minus median AUC3.17.810.72.43.3-3.2-3.13.23.1-2.92.62.32.1-2.2
Reaction time num false alarms1.42.03.91.81.3-1.3-1.31.31.2-1.70.82.01.4-0.9
Reaction time num false alarms AUC2.13.25.52.31.8-1.8-1.71.71.6-2.21.02.31.5-1.4
Reaction time trials correct on left0.51.02.2-0.7-1.11.00.9-0.9-0.91.5-1.0-0.9-0.91.2
Reaction time trials on left0.40.81.7-0.5-0.90.80.7-0.8-0.71.3-0.9-0.8-0.81.1
Reaction time mean0.50.81.50.71.1-1.2-1.01.21.1-1.10.50.30.1-0.9
Reaction time mean AUC0.30.40.80.60.7-0.9-0.70.80.7-0.80.10.1-0.2-0.7
Median of all reaction times0.10.20.7-0.2-0.20.00.1-0.0-0.10.1-0.6-0.7-0.90.0
Reaction time omissions7.410.814.83.63.9-3.6-3.43.53.3-3.52.72.62.0-3.7
Reaction time false alarm rate2.12.85.22.01.7-1.6-1.61.51.4-2.31.02.21.5-1.4
Reaction time premature initiation rate1.82.45.22.31.7-1.7-1.71.71.6-1.51.41.41.2-0.8
Reaction time premature initiations0.71.23.21.81.2-1.2-1.21.21.2-0.80.90.80.7-0.3
Std. dev. reaction times4.68.511.82.43.4-3.4-3.23.43.2-3.12.62.42.1-2.4
Reaction time trials completed0.40.81.7-0.5-0.90.80.7-0.8-0.71.3-0.9-0.8-0.81.1
Reaction time trials AUC0.71.42.6-0.8-1.31.21.1-1.1-1.11.6-1.2-1.1-1.11.3
Run reversals in cocaine runway, females0.60.61.91.10.9-0.3-0.40.30.3-0.71.10.50.7-1.4
Run reversals in cocaine runway, males1.21.32.30.41.0-1.3-1.21.21.1-1.50.51.50.91.1
Latency to leave start box in cocaine runway0.20.21.4-0.30.1-0.3-0.30.40.40.10.10.00.41.2
Latency to leave start box in cocaine runway, F0.91.01.40.91.2-1.2-1.21.21.2-0.91.10.71.0-0.2
Latency to leave start box in cocaine runway, M2.01.92.9-1.6-1.61.31.3-1.3-1.21.5-1.3-1.3-0.91.7
Std. dev. time between licks in bursts0.50.61.31.10.8-1.0-0.91.00.9-0.50.80.30.5-0.0
Total sessions with >9 infusions1.01.23.70.90.8-0.8-0.80.70.6-1.40.61.70.8-1.9
Short access day 1 total inactive lever presses1.11.54.11.51.2-1.0-1.01.00.8-1.40.71.40.8-2.0
Short access day 10 total inactive lever presses0.10.21.30.70.3-0.2-0.20.20.2-0.20.2-0.00.1-1.1
Short access day 1 total infusions0.30.42.40.60.5-0.3-0.30.20.2-0.70.40.80.3-1.5
Short access day 10 total infusions1.21.54.50.50.8-1.1-1.11.11.1-1.60.72.11.3-1.3
Short access total infusions1.01.33.91.31.1-0.9-0.90.90.8-1.20.91.30.8-2.0
Short access day 1 locomotion0.10.20.9-0.6-0.1-0.1-0.10.10.1-0.40.10.90.6-0.1
Short access day 10 total locomotion0.20.51.3-0.5-0.0-0.7-0.70.70.8-0.60.11.11.00.4
Short access total locomotion0.40.51.7-0.10.2-0.7-0.70.70.7-0.80.21.30.8-0.1
One hour access (0.3 mA shock)0.40.43.60.20.6-0.2-0.10.20.1-0.50.30.2-0.0-1.9
Compulsive drug intake0.20.20.40.20.4-0.4-0.50.40.4-0.40.50.50.60.2
One hour access (shock baseline)0.10.10.5-0.5-0.10.30.3-0.3-0.30.1-0.1-0.3-0.4-0.7
Social response proportion1.11.22.20.91.1-0.8-0.80.80.8-1.51.31.31.1-1.4
Social responses8.210.613.03.33.6-3.2-3.23.23.1-3.53.53.33.1-2.8
Social time1.21.62.40.21.4-1.4-1.31.41.4-1.51.11.41.0-1.1
Soleus weight1.03.04.6-2.1-1.91.71.7-1.7-1.71.6-1.8-1.7-1.61.4
Bone: stiffness12.620.423.9-4.9-4.74.84.9-4.8-4.84.5-4.4-4.4-4.42.8
Tibialis anterior weight2.27.39.5-3.1-3.02.92.9-2.9-2.82.5-2.8-2.4-2.52.0
Time to tail flick, vehicle, before self-admin1.71.86.82.21.4-1.2-1.11.11.0-0.70.90.30.3-2.6
Time to tail flick, vehicle, after self-admin0.20.31.10.20.6-0.3-0.30.30.3-0.51.00.30.5-1.0
Time to tail flick, test, before self-admin0.91.01.91.01.1-0.7-0.70.70.6-1.21.11.11.0-1.4
Time to tail flick, test, after self-admin0.30.31.4-1.10.40.10.1-0.10.00.11.20.10.5-0.0
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.7-0.40.40.4-0.4-0.40.3-0.1-0.3-0.30.4
Delta time to tail flick, test, before/after SA0.40.42.3-1.5-0.10.10.1-0.00.10.30.4-0.10.21.4
Tibia length5.715.720.3-3.1-4.04.54.4-4.5-4.44.5-3.3-4.3-3.91.8
Ambulatory time before self-admin1.01.64.12.01.2-1.0-1.11.00.9-0.91.20.80.9-2.0
Ambulatory time after self-admin0.50.63.82.00.2-0.1-0.10.1-0.10.5-0.3-0.8-0.8-1.3
Bone: tissue strength0.50.52.1-0.8-0.60.50.4-0.4-0.40.8-0.4-0.9-0.31.5
Total heroin consumption1.31.62.8-0.7-1.41.51.4-1.4-1.41.7-0.9-1.4-1.00.5
Bone: trabecular number3.76.18.5-2.1-2.52.62.7-2.6-2.72.3-2.8-2.4-2.90.9
Bone: trabecular spacing1.11.53.20.81.3-1.2-1.31.31.5-0.81.80.81.50.1
Bone: trabecular thickness0.50.62.90.70.7-0.6-0.50.50.4-1.00.11.00.3-1.7
Bone: trabecular tissue density0.20.20.6-0.20.3-0.5-0.50.50.6-0.30.40.50.80.4
Water consumed over 24 hours0.40.51.0-1.0-0.70.50.5-0.5-0.50.7-0.9-0.9-0.70.8
Number of responses in last shaping day0.30.41.6-1.2-0.2-0.2-0.20.20.3-0.40.01.10.9-0.1