Hub : Traits

Novel to familiar place preference ratio

Novel place preference divided by familiar place preference for males and females [%]

Tags: Behavior · Motivation · Novelty

Project: p50_shelly_flagel_2014

1 locus · 1 gene with independent associations · 1 total associated gene

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr18	969654	2367828	1	1	5.81e-09	5.45e-02	9.63e-03	LOC680026

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI without tail	2.56	1	0	0	0	1e+00	LOC680026
Glucose	2.85	1	0	0	0	1e+00	LOC680026
Number of licking bursts	3.99	1	0	0	0	1e+00	LOC680026
Food consumed during 24 hour testing period	4.38	1	0	0	0	1e+00	LOC680026
Times rat made contact with spout	6.91	1	0	0	0	1e+00	LOC680026
Mean time between licks in bursts	2.84	1	0	0	0	1e+00	LOC680026
Water consumed over 24 hours	10.54	1	0	0	0	1e+00	LOC680026
Reaction time premature initiation rate	3.61	1	0	0	0	1e+00	LOC680026
Reaction time premature initiations	3.68	1	0	0	0	1e+00	LOC680026
Condit. Reinf. active responses	2.98	1	0	0	0	1e+00	LOC680026
Condit. Reinf. inactive responses	5.89	1	0	0	0	1e+00	LOC680026
Condit. Reinf. lever presses	4.96	1	0	0	0	1e+00	LOC680026
Condit. Reinf. lever reinforcers received	2.99	1	0	0	0	1e+00	LOC680026
Locomotion velocity, session 1	3.62	1	0	0	0	1e+00	LOC680026
Locomotion velocity, session 2	4.5	1	0	0	0	1e+00	LOC680026
Locomotion velocity, hab. session 2	3.08	1	0	0	0	1e+00	LOC680026
Novelty place preference	28.12	1	1	100	0	1e+00	LOC680026
Time in novel zone, NPP test	28.01	1	1	100	0	1e+00	LOC680026
Pavlov. Cond. magazine entry latency	5.94	1	0	0	0	1e+00	LOC680026
Pavlov. Cond. index score	5.5	1	0	0	0	1e+00	LOC680026
Pavlov. Cond. latency score	3.38	1	0	0	0	1e+00	LOC680026
Pavlov. Cond. magazine entry number	8.33	1	0	0	0	1e+00	LOC680026
Pavlov. Cond. intertrial magazine entries	10.19	1	0	0	0	1e+00	LOC680026
Pavlov. Cond. lever-magazine prob. diff.	5.48	1	0	0	0	1e+00	LOC680026
Pavlov. Cond. response bias	3.99	1	0	0	0	1e+00	LOC680026
Bone: cortical porosity	4.59	1	0	0	0	1e+00	LOC680026
Bone: cortical porosity	5.5	1	0	0	0	1e+00	LOC680026
Bone: cortical thickness	4.44	1	0	0	0	1e+00	LOC680026
Bone: elastic work	3.21	1	0	0	0	1e+00	LOC680026
Bone: final force	2.78	1	0	0	0	1e+00	LOC680026
Bone: trabecular thickness	6.26	1	0	0	0	1e+00	LOC680026
Time to tail flick, vehicle, before self-admin	4.9	1	0	0	0	1e+00	LOC680026
Time to tail flick, test, before self-admin	4.27	1	0	0	0	1e+00	LOC680026
Total heroin consumption	6.04	1	0	0	0	1e+00	LOC680026
Fecal boli incidents, locomotor time 1	4.68	1	0	0	0	1e+00	LOC680026
Change in fecal boli incidents, locomotor task	13.55	1	0	0	0	1e+00	LOC680026
Seeking ratio, delayed vs. immediate footshock	3.74	1	0	0	0	1e+00	LOC680026
Cd content in liver	3.78	1	0	0	0	1e+00	LOC680026
Fe content in liver	9.78	1	0	0	0	1e+00	LOC680026
K content in liver	4.02	1	0	0	0	1e+00	LOC680026
Mn content in liver	15.69	1	0	0	0	1e+00	LOC680026
Rb content in liver	4.2	1	0	0	0	1e+00	LOC680026

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.05
Adipose	alternative TSS	0	0	1.06
Adipose	gene expression	1	0	1.02
Adipose	isoform ratio	0	0	1.03
Adipose	intron excision ratio	0	0	0.98
Adipose	mRNA stability	0	0	1.07
BLA	alternative polyA	0	0	1.01
BLA	alternative TSS	0	0	1.05
BLA	gene expression	0	0	1.03
BLA	isoform ratio	0	0	1.05
BLA	intron excision ratio	0	0	1
BLA	mRNA stability	0	0	1.03
Brain	alternative polyA	0	0	1.03
Brain	alternative TSS	0	0	1.06
Brain	gene expression	0	0	1.04
Brain	isoform ratio	0	0	1.02
Brain	intron excision ratio	0	0	1.07
Brain	mRNA stability	0	0	1.05
Eye	alternative polyA	0	0	1.07
Eye	alternative TSS	0	0	1.08
Eye	gene expression	0	0	1.06
Eye	isoform ratio	0	0	1.04
Eye	intron excision ratio	0	0	0.94
Eye	mRNA stability	0	0	1.17
IL	alternative polyA	0	0	0.96
IL	alternative TSS	0	0	1.05
IL	gene expression	0	0	1.01
IL	isoform ratio	0	0	0.98
IL	intron excision ratio	0	0	0.95
IL	mRNA stability	0	0	1.02
LHb	alternative polyA	0	0	1.05
LHb	alternative TSS	0	0	0.97
LHb	gene expression	0	0	1.05
LHb	isoform ratio	0	0	1.01
LHb	intron excision ratio	0	0	1
LHb	mRNA stability	0	0	1.08
Liver	alternative polyA	0	0	1.07
Liver	alternative TSS	0	0	1.08
Liver	gene expression	0	0	1.05
Liver	isoform ratio	0	0	1.04
Liver	intron excision ratio	0	0	1.02
Liver	mRNA stability	0	0	1.05
NAcc	alternative polyA	0	0	1.03
NAcc	alternative TSS	0	0	1.06
NAcc	gene expression	0	0	1.03
NAcc	isoform ratio	0	0	1.04
NAcc	intron excision ratio	0	0	1.05
NAcc	mRNA stability	0	0	1.03
OFC	alternative polyA	0	0	0.96
OFC	alternative TSS	0	0	1.07
OFC	gene expression	0	0	1.02
OFC	isoform ratio	0	0	1.01
OFC	intron excision ratio	0	0	0.95
OFC	mRNA stability	0	0	1.03
PL	alternative polyA	0	0	0.97
PL	alternative TSS	0	0	1.04
PL	gene expression	0	0	1.03
PL	isoform ratio	0	0	1.02
PL	intron excision ratio	0	0	1.03
PL	mRNA stability	0	0	1.04
pVTA	alternative polyA	0	0	1.05
pVTA	alternative TSS	0	0	1.03
pVTA	gene expression	0	0	1.03
pVTA	isoform ratio	0	0	1.06
pVTA	intron excision ratio	0	0	1
pVTA	mRNA stability	0	0	0.99
RMTg	alternative polyA	0	0	0.94
RMTg	alternative TSS	0	0	1.07
RMTg	gene expression	0	0	1.09
RMTg	isoform ratio	0	0	0.98
RMTg	intron excision ratio	0	0	1.03
RMTg	mRNA stability	0	0	1.05