Hub : Genes

Atp6v1d

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Atp6v1d 0.07 0.04 6.3e-03 0.03 0.03 0.03 0.03 6.8e-04 2.0e-03 1.8e-03 1.1e-03
2 BLA gene expression Atp6v1d 0.58 0.15 0.0e+00 0.31 0.31 0.29 0.31 2.6e-17 2.8e-17 7.0e-16 4.9e-17
3 NAcc gene expression Atp6v1d 0.26 0.1 0.0e+00 0.25 0.24 0.24 0.24 3.3e-28 5.4e-28 1.7e-27 1.2e-27
4 OFC gene expression Atp6v1d 0.5 0.14 4.8e-10 0.33 0.37 0.34 0.33 1.4e-08 1.1e-09 7.9e-09 1.5e-08
5 IL gene expression Atp6v1d 0.73 0.13 9.5e-15 0.37 0.41 0.36 0.42 6.7e-10 5.0e-11 1.9e-09 2.3e-11
6 Brain gene expression Atp6v1d 0.58 0.11 0.0e+00 0.52 0.58 0.59 0.59 2.5e-56 6.4e-66 6.2e-67 6.4e-67
7 pVTA gene expression Atp6v1d 0.34 0.12 2.7e-13 0.29 0.29 0.27 0.28 5.8e-13 6.2e-13 5.2e-12 8.6e-13
8 PL gene expression Atp6v1d 0.32 0.1 0.0e+00 0.33 0.36 0.33 0.34 1.5e-37 2.4e-41 2.7e-37 6.1e-39
9 Liver gene expression Atp6v1d 0.09 0.05 2.3e-10 0.07 0.09 0.1 0.05 1.9e-08 6.1e-10 6.0e-11 1.2e-06
10 LHb gene expression Atp6v1d 0.44 0.15 7.7e-08 0.36 0.3 0.28 0.32 1.6e-09 7.0e-08 2.6e-07 1.7e-08
11 Adipose gene expression Atp6v1d 0.1 0.05 3.3e-11 0.05 0.09 0.08 0.09 5.6e-06 5.1e-10 1.4e-09 8.2e-10
12 Liver mRNA stability Atp6v1d 0.04 0.02 1.5e-04 0.01 0.03 0.03 0.01 4.6e-02 4.3e-04 6.2e-04 8.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.11.93.10.91.61.8-1.4-1.51.41.5-1.51.41.5-1.1-0.1
Area under the delay curve0.00.10.20.20.30.3-0.2-0.20.10.4-0.10.30.10.00.2
BMI with tail1.13.75.62.2-1.7-1.82.32.2-2.3-1.92.4-1.2-2.01.6-0.2
BMI without tail0.20.53.01.7-0.3-0.20.70.6-0.7-0.20.80.1-0.40.50.0
Body weight1.14.536.16.0-0.4-0.41.81.2-1.5-0.51.61.3-0.4-0.2-2.3
Weight adjusted by age1.51.75.52.31.41.2-0.6-1.00.80.9-0.71.71.5-1.4-1.2
Bone surface2.03.55.70.92.32.4-2.2-2.12.12.0-2.01.91.7-1.50.2
Bone volume2.23.75.71.52.22.3-1.8-2.02.02.0-1.82.41.9-2.0-0.8
Breakpoint value in progressive ratio session1.01.17.42.70.20.20.60.2-0.30.10.41.20.4-0.8-1.8
Number of licking bursts1.31.510.3-3.2-0.1-0.1-0.8-0.30.5-0.2-0.6-1.4-0.10.81.9
Context. condit. distance diff. score2.73.35.31.5-1.9-2.02.32.1-2.1-2.02.3-1.2-1.71.3-0.5
Locomotion velocity, session 11.01.12.0-0.11.21.3-1.4-1.21.21.1-1.30.91.0-0.70.4
Locomotion distance, session 11.41.83.1-1.3-1.3-1.20.91.2-1.0-1.41.0-1.8-1.71.71.4
Locomotion velocity, session 20.20.20.4-0.4-0.6-0.30.30.4-0.3-0.40.4-0.6-0.40.60.4
Locomotion distance, session 20.40.62.5-1.6-0.6-0.50.10.4-0.2-0.70.2-1.1-0.70.80.8
Locomotion velocity, session 30.40.43.2-0.1-0.2-0.20.30.00.0-0.30.10.60.1-1.2-1.8
Locomotion distance, session 30.40.41.4-0.60.30.3-0.4-0.50.60.3-0.50.60.4-1.2-1.1
Stereotopy head waving bouts, day 31.31.53.71.91.01.1-0.3-0.80.70.9-0.41.91.2-1.6-1.6
Stereotopy head waving duration, day 30.60.72.11.50.40.5-0.0-0.40.40.4-0.11.30.7-1.2-1.4
Locomotion velocity, session 71.31.42.3-0.2-1.4-1.41.51.3-1.3-1.31.5-0.8-1.20.4-0.9
Locomotion distance, session 71.31.72.5-0.9-1.4-1.31.11.4-1.3-1.21.2-1.6-1.41.61.0
Stereotopy head waving bouts, day 71.11.35.12.30.50.50.1-0.30.30.50.11.70.9-1.4-2.0
Stereotopy head waving duration, day 71.21.56.92.60.30.20.4-0.10.00.30.31.60.5-1.5-2.4
Locomotion velocity, session 81.01.21.71.3-1.0-1.01.31.3-1.3-1.21.3-0.8-1.01.20.2
Locomotion distance, session 82.84.16.10.4-2.3-2.32.32.3-2.2-2.52.4-1.8-2.21.7-0.0
Degree of sensitization distance1.41.43.5-0.1-1.0-0.90.91.2-1.2-0.81.0-1.4-1.21.91.5
Degree of sensitization stereotypy0.70.74.02.0-0.0-0.10.40.1-0.10.10.41.00.3-0.8-1.6
Conditioned locomotion0.30.42.7-1.60.20.2-0.4-0.50.70.1-0.40.10.1-0.7-0.3
Cocaine response after cond. corrected2.83.14.8-0.8-2.2-2.12.02.0-1.9-2.12.0-1.5-1.91.1-0.6
Cocaine response after cond. not corrected3.64.05.6-0.2-2.4-2.42.22.3-2.3-2.32.3-1.7-2.31.6-0.2
Cocaine response before conditioning0.10.20.90.90.10.00.00.1-0.2-0.10.30.0-0.30.70.7
Saline control response0.20.31.3-0.3-0.3-0.20.10.4-0.3-0.20.3-0.6-0.40.91.1
Bone: connectivity density0.10.10.50.70.40.4-0.2-0.20.20.2-0.20.2-0.2-0.1-0.0
Bone: cortical apparent density3.14.16.9-2.62.12.1-2.5-2.42.42.0-2.50.71.4-1.11.5
Bone: cortical area0.71.02.30.60.80.9-0.9-1.01.00.6-0.91.40.6-1.5-1.3
Bone: cortical porosity0.50.51.51.2-0.7-0.60.90.9-0.9-0.60.8-0.2-0.60.4-0.4
Bone: cortical porosity0.20.21.31.1-0.2-0.20.40.4-0.4-0.20.30.1-0.10.1-0.4
Bone: cortical thickness0.61.02.1-0.9-1.3-1.10.90.9-0.8-1.40.8-0.9-1.40.3-0.5
Bone: cortical thickness3.54.16.2-2.4-2.4-2.31.61.9-1.7-2.41.7-2.5-2.21.90.8
Bone: cortical tissue density3.24.26.8-2.62.12.1-2.5-2.42.52.0-2.50.71.4-1.01.5
Condit. Reinf. active minus inactive responses0.30.41.61.3-0.4-0.40.90.5-0.8-0.40.6-0.0-0.10.1-0.7
Condit. Reinf. active-inactive response ratio0.30.30.70.70.40.40.0-0.40.20.4-0.30.70.7-0.7-0.9
Condit. Reinf. active responses0.50.61.00.7-0.7-0.71.00.8-1.0-0.80.7-0.7-0.50.8-0.0
Condit. Reinf. inactive responses1.41.73.8-0.3-1.1-1.20.91.3-1.2-1.31.0-1.9-1.31.91.6
Incentive salience index mean0.50.61.51.2-0.6-0.71.10.8-1.0-0.70.8-0.4-0.50.4-0.6
Condit. Reinf. lever presses0.10.10.70.90.10.00.10.0-0.2-0.1-0.0-0.0-0.20.0-0.2
Condit. Reinf. active minus inactive responses1.11.48.6-0.5-0.2-0.2-0.10.4-0.3-0.10.2-1.5-0.42.12.9
Condit. Reinf. active-inactive response ratio0.50.53.7-0.30.10.1-0.30.00.00.3-0.1-0.8-0.01.21.9
Condit. Reinf. active responses0.40.53.60.40.50.6-0.6-0.20.30.6-0.4-0.30.31.01.9
Condit. Reinf. inactive responses0.20.20.30.30.50.6-0.4-0.40.50.5-0.50.60.3-0.4-0.0
Condit. Reinf. lever presses1.31.82.81.61.61.7-1.2-1.31.31.5-1.31.51.4-0.90.1
Condit. Reinf. lever reinforcers received0.40.64.00.40.40.5-0.5-0.20.20.5-0.4-0.40.41.12.0
Conditioned reinforcement - actives1.01.01.40.5-1.1-1.11.11.2-1.2-1.01.1-1.1-0.91.10.3
Conditioned reinforcement - inactives0.81.01.4-0.6-1.2-1.20.91.1-1.0-1.01.0-1.1-1.11.00.3
Conditioned locomotion1.11.32.1-0.6-1.4-1.51.21.3-1.3-1.21.2-1.1-1.30.8-0.3
Patch foraging indifference point 0 sec1.52.54.10.91.92.0-1.8-1.71.81.7-1.61.11.7-0.41.4
Patch foraging indifference point AUC0.10.10.3-0.20.10.2-0.2-0.10.10.1-0.3-0.10.20.20.6
Delay disc. indifference point, 0s delay0.60.74.1-0.2-0.2-0.2-0.00.3-0.4-0.20.2-1.1-0.51.52.0
Delay disc. indifference point, 16s delay0.80.81.50.11.01.0-0.8-1.01.01.0-0.71.20.6-1.2-0.7
Delay disc. indifference point, 2s delay0.50.61.00.7-0.7-0.70.80.9-1.0-0.50.9-0.6-0.61.00.4
Delay disc. indifference point, 24s delay0.10.10.6-0.80.30.3-0.4-0.30.40.3-0.30.10.2-0.20.2
Delay disc. indifference point, 4s delay0.30.30.6-0.80.50.5-0.7-0.60.60.7-0.70.40.5-0.50.1
Delay disc. indifference point, 8s delay0.10.10.80.90.40.4-0.1-0.10.00.5-0.10.50.10.10.2
Indifference point function ln k0.10.10.60.80.30.2-0.3-0.20.20.2-0.10.10.20.20.4
Indifference point function log k0.10.10.60.80.30.2-0.3-0.20.20.2-0.10.10.20.20.4
Patch foraging total patch changes 0 sec1.52.43.90.81.92.0-1.8-1.61.81.7-1.60.91.6-0.21.7
Patch foraging total patch changes 12 sec0.60.81.51.21.01.2-0.8-0.80.90.9-0.71.00.9-0.7-0.0
Patch foraging total patch changes 18 sec1.21.62.70.71.61.7-1.4-1.31.41.5-1.31.11.2-0.60.8
Patch foraging total patch changes 24 sec0.80.92.01.41.21.2-0.7-1.01.10.9-0.61.10.9-0.8-0.1
Patch foraging total patch changes 6 sec0.91.32.0-0.01.31.4-1.4-1.21.31.3-1.20.71.3-0.31.1
Patch foraging time to switch 0 sec0.50.74.5-0.30.10.10.1-0.30.40.1-0.00.9-0.2-1.7-2.1
Patch foraging water rate 0 sec0.50.82.31.5-0.4-0.40.60.7-0.8-0.50.7-0.6-0.31.51.3
Patch foraging water rate 12 sec0.30.52.20.6-0.4-0.30.20.6-0.5-0.30.3-0.70.01.41.5
Patch foraging water rate 18 sec1.82.46.72.6-1.4-1.31.91.6-1.8-1.41.8-0.6-1.11.2-0.5
Patch foraging water rate 24 sec1.41.94.31.8-1.1-1.11.31.5-1.5-1.01.4-1.2-1.02.11.3
Patch foraging water rate 6 sec0.60.85.12.30.80.8-0.4-0.50.30.7-0.40.91.2-0.10.1
Seeking ratio, delayed vs. immediate footshock0.10.20.9-1.0-0.4-0.20.00.20.0-0.30.1-0.5-0.30.30.4
Distance traveled before self-admin0.40.40.70.2-0.7-0.60.70.8-0.8-0.70.7-0.6-0.90.60.1
Distance traveled after self-admin0.30.41.41.20.20.30.2-0.10.00.30.10.80.3-0.7-1.1
Extensor digitorum longus weight0.10.42.11.5-0.3-0.30.60.5-0.6-0.20.80.3-0.70.3-0.2
Bone: elastic displacement0.91.12.5-1.6-1.1-1.10.70.9-0.9-0.90.7-1.3-1.11.00.6
Bone: elastic work2.43.04.6-0.1-2.0-1.91.92.0-2.0-1.91.8-1.7-2.11.60.2
Bone: endosteal estimation3.47.311.41.92.83.0-2.6-2.82.82.8-2.53.43.0-2.9-1.4
Bone: endosteal perimeter2.65.48.32.02.42.5-2.3-2.42.42.2-2.12.92.4-2.5-1.3
Epididymis fat weight0.20.61.71.30.70.9-0.4-0.60.70.6-0.50.90.5-0.8-0.6
Delta time in closed arm before/after self-admin0.40.40.7-0.50.60.6-0.8-0.70.80.4-0.80.20.7-0.50.2
Delta time in open arm before/after self-admin0.10.10.50.60.10.10.20.2-0.30.30.20.1-0.10.60.7
Diff in mean of infusions in LGA sessions0.40.42.41.50.70.8-0.4-0.40.50.5-0.30.40.30.10.7
Delay discount exponential model param0.00.00.1-0.2-0.2-0.20.10.1-0.1-0.40.1-0.3-0.10.0-0.1
Extinction: sum of active levers before priming1.61.65.91.80.70.70.0-0.40.20.8-0.31.91.1-1.8-2.4
Active lever presses in extinction session 61.61.64.32.11.21.4-0.6-0.90.71.3-0.81.81.5-1.1-0.9
Bone: final force1.01.73.71.9-1.3-1.11.51.3-1.3-1.31.5-0.1-1.10.2-1.5
Bone: final moment0.60.93.61.9-0.9-0.71.10.9-0.9-0.81.00.2-0.7-0.0-1.2
Food consumed during 24 hour testing period0.30.31.01.0-0.5-0.50.70.6-0.7-0.40.7-0.1-0.50.3-0.3
Glucose0.60.86.4-2.50.10.1-0.8-0.50.60.1-0.6-0.70.10.21.2
Heart weight2.23.14.8-0.22.12.0-2.1-2.02.02.2-2.11.41.9-1.10.7
Delay discount hyperbolic model param0.00.00.1-0.1-0.1-0.10.00.00.1-0.30.0-0.20.0-0.1-0.1
Intermittent access intake day 1-15 change1.51.54.0-1.6-0.9-0.90.40.8-0.8-0.80.5-1.8-1.11.82.0
Intermittent access intake escalation2.02.04.2-1.5-1.2-1.30.71.1-1.2-1.10.8-2.0-1.32.01.9
Intermittent access intake escalation 20.90.91.6-1.1-1.0-1.10.70.8-0.8-1.00.7-1.3-1.01.00.5
Intermitt. access day 1 inactive lever presses0.10.10.7-0.10.10.1-0.20.1-0.00.2-0.1-0.20.00.50.8
Intermitt. access day 15 inactive lever presses2.32.53.80.6-1.8-1.71.91.9-1.8-1.62.0-1.2-1.81.4-0.2
Intermitt. access escalation Index0.20.10.2-0.1-0.4-0.50.50.4-0.5-0.20.4-0.3-0.30.40.0
Intermittent access day 1 total infusions0.30.41.6-0.10.20.3-0.2-0.40.50.4-0.30.80.4-1.1-1.3
Intermittent access day 15 total infusions0.80.82.2-1.5-0.9-1.00.50.8-0.7-0.70.6-1.3-0.91.00.8
Intermittent access terminal intake (last 3 days)0.10.20.4-0.6-0.5-0.50.30.4-0.3-0.40.3-0.3-0.3-0.0-0.4
Intermittent access total infusions0.20.21.5-1.20.00.0-0.4-0.20.30.3-0.3-0.10.1-0.10.2
Intermittent access day 1 locomotion0.10.10.5-0.70.20.3-0.4-0.20.40.3-0.30.30.3-0.3-0.1
Intermittent access day 15 total locomotion0.30.40.8-0.9-0.6-0.70.40.5-0.6-0.40.4-0.8-0.50.70.5
Intermittent access total locomotion0.10.10.4-0.6-0.3-0.30.20.2-0.2-0.10.2-0.1-0.2-0.0-0.3
Intermittent access standard deviation0.40.41.8-1.3-0.3-0.3-0.20.00.1-0.30.0-0.9-0.70.61.1
Left kidney weight0.30.72.70.80.60.6-0.3-0.60.60.4-0.31.20.4-1.4-1.6
Right kidney weight0.20.42.50.40.20.1-0.0-0.30.40.00.00.9-0.0-1.2-1.6
Cocaine induced anxiety4.85.58.0-0.3-2.8-2.82.72.7-2.7-2.62.8-2.0-2.51.8-0.4
Post-drug Anxiety0.10.10.2-0.3-0.4-0.40.40.4-0.4-0.40.4-0.2-0.50.2-0.2
Baseline Anxiety4.75.07.1-0.92.52.5-2.6-2.62.62.3-2.71.92.2-2.1-0.0
Tail length1.03.011.53.41.31.5-0.6-1.00.91.6-0.72.61.6-1.8-1.9
Length with tail1.03.523.64.90.50.60.6-0.1-0.20.60.32.30.9-1.5-2.9
Length without tail1.22.614.03.7-0.8-0.81.71.1-1.3-1.01.40.7-0.6-0.3-2.4
Times rat made contact with spout0.60.71.81.30.90.9-0.4-0.70.60.9-0.51.30.6-1.0-0.8
Lifetime Intake0.20.21.7-1.30.00.0-0.4-0.20.30.2-0.3-0.10.2-0.20.1
Liver weight, left1.11.82.8-1.61.21.3-1.7-1.31.51.3-1.60.11.2-0.11.7
Liver weight, right0.20.41.0-0.30.50.6-0.5-0.60.70.5-0.60.80.6-1.0-0.8
Locomotor activity1.11.89.93.2-0.6-0.61.61.0-1.2-0.71.30.4-0.8-0.0-1.6
Locomotor testing distance0.30.63.21.8-0.2-0.31.00.5-0.7-0.40.70.2-0.5-0.0-0.9
Locomotor testing rearing0.30.52.01.40.60.50.1-0.30.10.6-0.20.90.5-0.7-1.1
Locomotion in novel chamber0.10.11.3-1.10.1-0.0-0.3-0.20.30.0-0.3-0.3-0.1-0.10.2
Locomotion in novel chamber post-restriction0.40.52.71.5-0.1-0.10.60.2-0.3-0.30.40.5-0.1-0.7-1.6
Fecal boli incidents, locomotor time 11.81.93.30.0-1.6-1.81.61.6-1.6-1.51.6-1.1-1.41.1-0.2
Change in fecal boli incidents, locomotor task1.11.01.9-1.10.80.9-1.1-1.21.30.9-1.00.90.7-1.4-0.6
Time >=10cm from walls, locomotor time 12.12.13.51.6-1.5-1.61.91.7-1.7-1.51.8-0.5-1.20.6-1.2
Bouts of movement, locomotor time 13.33.64.90.72.12.0-1.9-2.01.92.2-2.02.22.2-1.9-0.6
Total resting periods, locomotor time 13.13.44.80.42.12.0-1.9-2.01.92.1-2.02.12.2-1.9-0.5
Rest time, locomotor task time 10.70.81.1-0.90.90.9-1.1-1.01.01.0-1.10.80.9-0.90.0
Distance moved, locomotor task time 10.40.50.70.7-0.7-0.50.80.7-0.7-0.80.7-0.8-0.70.7-0.0
Vertical activity count, locomotor time 12.52.63.40.2-1.8-1.71.71.8-1.7-1.81.8-1.7-1.81.70.4
Time >=10cm from walls, locomotor time 26.77.19.50.4-3.0-3.13.03.1-3.1-3.03.0-2.5-2.92.4-0.1
Bouts of movement, locomotor time 22.93.15.3-1.02.01.9-2.3-2.02.02.1-2.21.21.8-0.91.2
Total resting periods, locomotor time 23.73.96.6-1.42.22.1-2.6-2.22.32.2-2.41.21.9-1.01.4
Rest time, locomotor task time 20.70.95.4-2.30.20.0-0.8-0.50.60.3-0.7-0.80.10.51.5
Distance moved, locomotor task time 20.50.63.21.8-0.5-0.20.90.7-0.8-0.70.8-0.1-0.40.3-0.6
Vertical activity count, locomotor time 21.01.11.50.7-1.1-0.91.21.2-1.2-1.21.2-0.9-1.21.0-0.0
Light reinforcement 11.12.012.33.5-0.8-0.81.61.2-1.7-1.01.30.0-0.30.8-0.9
Light reinforcement 20.60.81.70.9-0.9-1.01.11.0-1.3-1.10.9-0.7-0.50.9-0.1
Bone: marrow area3.67.912.22.03.03.1-2.7-2.92.92.9-2.63.53.1-3.0-1.4
Bone: maximum diameter2.54.76.41.02.32.4-2.5-2.42.52.0-2.22.52.1-2.4-0.9
Bone: maximum force0.81.47.02.0-0.5-0.40.90.5-0.5-0.60.81.1-0.4-1.2-2.6
Bone: maximum moment0.61.15.51.9-0.00.10.40.00.0-0.10.31.30.1-1.4-2.3
Mean time between licks in bursts0.40.54.8-2.2-0.4-0.4-0.1-0.10.2-0.2-0.2-0.6-0.6-0.10.1
Mean num. licks in bursts1.82.213.53.70.50.50.6-0.0-0.20.60.42.00.3-1.3-2.3
Cd content in liver2.02.23.6-0.6-1.6-1.71.51.6-1.5-1.71.5-1.9-1.51.60.6
Co content in liver0.50.62.41.50.60.7-0.4-0.60.60.6-0.30.90.5-0.8-0.8
Cu content in liver1.51.83.80.2-1.3-1.31.21.4-1.5-1.21.2-1.7-0.91.91.3
Fe content in liver2.02.33.4-0.61.81.7-1.9-1.71.81.7-1.81.21.7-1.20.4
K content in liver0.30.30.8-0.30.60.5-0.7-0.60.60.6-0.80.30.9-0.40.1
Mg content in liver1.61.63.1-0.91.51.3-1.6-1.41.41.4-1.80.41.4-0.51.0
Mn content in liver1.31.52.4-0.31.21.2-1.5-1.51.41.3-1.60.91.6-1.00.0
Na content in liver0.20.20.50.20.50.4-0.5-0.30.30.3-0.50.20.7-0.10.3
Rb content in liver1.11.32.6-1.11.11.0-1.5-1.31.31.0-1.3-0.01.20.01.6
Se content in liver0.30.30.8-0.4-0.5-0.60.30.5-0.4-0.50.4-0.9-0.50.80.8
Sr content in liver0.70.71.1-0.1-1.0-0.91.10.9-0.9-1.01.0-0.7-0.70.4-0.4
Zn content in liver0.20.30.6-0.20.50.5-0.5-0.50.30.6-0.8-0.20.70.20.8
Bone: minimum diameter4.48.112.91.42.93.1-2.8-3.03.02.9-2.83.63.0-3.4-1.9
Time in familiar zone, hab. session 12.62.53.6-1.41.61.7-1.8-1.81.81.7-1.90.91.8-1.10.5
Time in novel zone, hab. session 12.32.33.31.5-1.5-1.61.81.7-1.8-1.61.8-0.7-1.60.9-0.9
Total zone transitions, hab. session 10.60.81.4-0.2-1.1-1.11.11.1-1.0-1.21.2-0.5-1.00.4-0.5
Total locomotion distance, hab. session 11.62.33.5-1.1-1.9-1.81.61.6-1.4-1.81.8-1.4-1.71.0-0.1
Locomotion velocity, hab. session 11.42.03.0-1.1-1.7-1.61.51.5-1.3-1.71.6-1.4-1.61.10.1
Time in familiar zone, hab. session 21.01.01.80.71.21.1-0.9-1.00.91.3-1.01.21.3-0.70.1
Time in novel zone, hab. session 22.52.53.7-0.3-1.8-1.81.61.7-1.6-1.81.7-1.8-1.91.50.3
Total zone transitions, hab. session 20.70.91.30.5-1.0-0.91.01.1-1.1-1.01.1-0.8-1.11.00.3
Total locomotion distance, hab. session 21.72.23.0-0.2-1.6-1.51.41.6-1.5-1.71.6-1.6-1.71.70.8
Locomotion velocity, hab. session 21.41.92.7-0.2-1.5-1.51.41.5-1.4-1.61.5-1.4-1.61.40.5
Novel to familiar place preference ratio1.11.11.8-0.3-1.3-1.31.21.1-1.0-1.11.3-0.4-1.2-0.0-1.2
Novelty place preference0.70.72.30.0-1.0-1.00.90.7-0.7-0.71.00.0-0.9-0.4-1.5
Time in novel zone, NPP test0.80.81.5-0.1-1.1-1.11.10.9-0.9-0.91.1-0.2-1.0-0.1-1.2
Total zone transitions, NPP test0.60.91.40.9-0.8-0.80.91.1-1.0-0.91.1-0.8-1.01.20.6
Total locomotion distance, NPP test1.82.54.21.3-1.7-1.61.91.8-1.8-1.82.1-0.9-1.81.1-0.5
Locomotion velocity, NPP test1.72.44.11.3-1.7-1.61.91.8-1.7-1.82.0-0.7-1.80.8-1.0
Intraocular pressure4.15.78.1-0.1-2.8-2.62.52.7-2.4-2.82.7-2.6-2.42.40.6
Delta distance traveled before/after self-admin1.31.42.41.01.31.4-1.0-1.21.11.4-1.11.41.5-1.0-0.3
Delta ambulatory time before/after self-admin1.31.42.30.81.41.4-1.1-1.31.21.4-1.21.31.5-1.0-0.2
Parametrial fat weight0.30.62.51.30.30.30.0-0.30.20.2-0.11.00.5-1.1-1.6
Pavlov. Cond. lever latency0.50.61.0-0.8-1.0-0.91.00.8-0.7-0.90.9-0.4-0.6-0.1-0.9
Pavlov. Cond. magazine entry latency1.01.33.92.01.31.2-0.8-0.90.81.1-0.81.60.8-1.0-0.6
Pavlov. Cond. change in total contacts1.51.66.12.51.41.3-0.8-0.90.71.3-0.91.51.3-0.8-0.4
Pavlov. Cond. index score0.81.03.31.81.21.1-0.8-0.90.71.1-0.91.20.9-0.6-0.2
Pavlov. Cond. latency score0.91.12.71.61.31.2-1.0-1.00.91.2-1.01.20.9-0.7-0.1
Pavlov. Cond. lever contacts1.11.32.21.11.51.4-1.4-1.21.11.4-1.30.91.0-0.30.8
Pavlov. Cond. magazine entry number0.70.94.2-2.1-1.1-1.00.60.6-0.5-1.00.6-1.1-0.80.3-0.0
Pavlov. Cond. intertrial magazine entries1.41.72.9-0.5-1.4-1.41.21.4-1.3-1.31.3-1.6-1.01.71.1
Pavlov. Cond. lever-magazine prob. diff.0.91.12.51.61.31.2-0.9-0.90.81.1-1.01.21.0-0.7-0.1
Pavlov. Cond. response bias0.70.84.82.21.00.9-0.5-0.50.30.9-0.51.00.6-0.10.2
Pavlov. Cond. lever latency0.81.11.8-1.1-1.3-1.30.91.1-1.0-1.31.0-1.0-1.30.6-0.2
Pavlov. Cond. magazine entry latency0.10.10.60.80.10.10.40.0-0.30.10.00.20.1-0.1-0.4
Pavlov. Cond. change in total contacts1.62.23.51.51.81.9-1.3-1.51.31.8-1.51.41.9-0.90.3
Pavlov. Cond. index score0.40.61.01.00.91.0-0.5-0.70.60.9-0.70.61.0-0.30.2
Pavlov. Cond. latency score0.50.61.11.01.01.0-0.5-0.70.60.9-0.70.71.1-0.5-0.0
Pavlov. Cond. lever contacts0.81.12.31.51.21.3-0.8-1.00.91.2-0.91.21.1-0.8-0.1
Pavlov. Cond. magazine entry number0.10.10.2-0.5-0.0-0.0-0.4-0.20.40.00.00.4-0.2-0.5-0.3
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.0-0.1-0.1-0.10.1-0.0-0.10.1-0.2-0.50.40.6
Pavlov. Cond. lever-magazine prob. diff.0.50.71.20.91.01.1-0.6-0.80.71.0-0.80.71.1-0.40.2
Pavlov. Cond. response bias0.60.81.51.21.11.1-0.6-0.80.71.0-0.80.81.0-0.50.1
Time in closed arm before self-admin0.20.20.70.8-0.4-0.40.60.6-0.6-0.30.6-0.1-0.50.4-0.1
Time in closed arm after self-admin0.10.10.20.40.30.4-0.3-0.40.50.1-0.40.20.3-0.4-0.1
Time in open arm before self-admin0.20.21.1-0.1-0.2-0.00.1-0.10.2-0.50.10.2-0.0-0.7-1.1
Time in open arm after self-admin1.01.11.80.51.31.3-0.9-1.11.01.3-0.91.31.2-0.8-0.0
Bone: periosteal estimation2.45.08.51.62.22.4-2.2-2.32.42.1-2.02.92.2-2.6-1.5
Bone: periosteal perimeter3.04.98.52.42.32.4-2.1-2.22.22.0-1.92.92.2-2.4-1.4
Bone: post-yield work0.60.82.10.70.70.6-0.6-0.80.80.5-0.41.50.5-1.5-1.5
Progressive ratio test 1 active lever presses0.00.00.2-0.4-0.2-0.20.00.10.0-0.00.10.1-0.2-0.2-0.2
Progressive ratio test 1 breakpoint0.10.10.2-0.30.20.1-0.2-0.20.30.3-0.10.40.1-0.5-0.4
Progressive ratio test 1 inactive lever presses0.30.30.5-0.60.50.5-0.7-0.60.70.7-0.60.40.6-0.40.3
Progressive ratio test 2 active lever presses0.50.50.9-0.3-0.9-0.90.70.8-0.6-0.90.9-0.7-0.90.5-0.1
Progressive ratio test 2 breakpoint0.30.30.60.0-0.7-0.70.60.7-0.5-0.70.7-0.5-0.80.4-0.1
Progressive ratio test 2 inactive lever presses0.91.11.8-0.7-1.3-1.31.01.2-0.9-1.21.2-1.0-1.20.7-0.1
Incentive Sensitization - Responses0.90.91.50.3-1.1-1.11.11.0-0.9-1.11.2-0.8-1.20.7-0.2
Incentive Sensitization - Breakpoint1.11.11.70.4-1.2-1.21.21.1-1.0-1.21.3-0.9-1.30.9-0.0
Sum of active levers in priming session hrs 5-61.91.88.83.00.30.40.60.1-0.30.40.21.70.7-1.4-2.6
Progressive ratio0.20.20.91.00.40.4-0.2-0.40.40.3-0.10.70.4-0.6-0.6
Food seeking constrained by brief footshock0.30.30.70.4-0.5-0.30.60.6-0.5-0.70.7-0.5-0.80.70.4
Seeking ratio, punishment vs. effort0.30.40.6-0.2-0.7-0.60.60.8-0.7-0.60.7-0.7-0.80.80.4
Retroperitoneal fat weight0.41.31.91.1-1.0-0.91.31.3-1.4-1.01.2-1.0-1.21.40.4
Reaction time number correct3.85.48.40.1-2.6-2.62.42.5-2.5-2.92.5-2.5-2.42.50.7
Reaction time mean minus median0.70.92.3-1.51.00.9-1.1-1.21.30.8-1.00.20.2-0.50.8
Reaction time mean minus median AUC0.60.82.2-1.50.90.8-1.0-1.01.10.6-0.9-0.00.1-0.11.1
Reaction time num false alarms1.11.52.40.3-1.4-1.31.51.4-1.4-1.41.4-1.2-1.11.10.0
Reaction time num false alarms AUC1.62.23.60.7-1.6-1.61.91.7-1.7-1.61.7-1.3-1.51.3-0.1
Reaction time trials correct on left3.85.48.40.1-2.6-2.62.42.5-2.5-2.92.5-2.5-2.42.50.7
Reaction time trials on left3.65.27.9-0.1-2.5-2.52.32.4-2.3-2.82.4-2.5-2.42.50.9
Reaction time mean4.46.29.3-1.93.02.8-3.1-3.03.02.7-2.91.62.0-1.61.3
Reaction time mean AUC4.15.58.3-1.92.82.7-2.9-2.82.92.5-2.71.41.8-1.51.4
Median of all reaction times5.17.010.5-1.63.23.0-3.2-3.13.23.0-3.11.82.3-1.81.3
Reaction time omissions2.02.87.0-2.61.51.5-2.1-1.71.91.3-1.8-0.10.6-0.02.4
Reaction time false alarm rate0.10.10.30.6-0.2-0.10.50.3-0.40.00.3-0.0-0.10.0-0.3
Reaction time premature initiation rate0.81.04.82.2-0.5-0.61.00.8-0.9-0.21.00.7-0.4-0.4-1.7
Reaction time premature initiations2.23.14.72.0-1.8-1.92.12.0-2.1-1.82.2-0.7-1.61.0-1.0
Std. dev. reaction times1.82.55.1-2.31.71.5-2.0-1.81.91.4-1.80.30.7-0.51.6
Reaction time trials completed3.65.27.9-0.1-2.5-2.52.32.4-2.3-2.82.4-2.5-2.42.50.9
Reaction time trials AUC3.95.68.3-0.3-2.6-2.62.32.5-2.4-2.92.4-2.7-2.52.71.2
Run reversals in cocaine runway, females0.90.81.50.31.01.2-0.9-0.90.81.2-1.00.91.2-0.70.0
Run reversals in cocaine runway, males1.00.91.4-0.51.11.1-1.2-1.11.11.1-1.20.21.0-0.11.0
Latency to leave start box in cocaine runway1.61.82.9-1.11.41.5-1.7-1.41.51.6-1.60.61.0-0.11.7
Latency to leave start box in cocaine runway, F1.21.32.0-0.41.31.3-1.4-1.31.31.3-1.30.91.0-0.50.8
Latency to leave start box in cocaine runway, M1.11.01.7-1.20.91.1-1.3-1.01.21.2-1.20.50.7-0.31.1
Std. dev. time between licks in bursts0.70.92.2-1.00.70.7-0.6-0.90.91.0-0.91.00.8-1.5-1.0
Total sessions with >9 infusions0.30.40.80.20.60.6-0.5-0.50.40.9-0.60.80.8-0.6-0.4
Short access day 1 total inactive lever presses0.70.81.30.21.10.9-0.9-1.01.00.8-1.00.91.1-1.0-0.4
Short access day 10 total inactive lever presses2.02.33.10.0-1.7-1.61.61.7-1.7-1.71.6-1.5-1.81.50.2
Short access day 1 total infusions0.60.61.10.30.70.7-0.5-0.70.70.8-0.61.01.0-1.1-0.9
Short access day 10 total infusions0.91.01.4-0.41.11.1-1.2-1.11.21.2-1.20.91.1-1.0-0.1
Short access total infusions0.50.50.7-0.70.70.6-0.8-0.80.80.8-0.80.60.8-0.8-0.2
Short access day 1 locomotion0.20.20.70.70.20.30.0-0.00.00.4-0.10.80.5-0.6-0.9
Short access day 10 total locomotion1.51.73.51.41.31.3-0.8-1.11.01.3-0.91.91.4-1.7-1.4
Short access total locomotion1.61.62.80.51.41.4-1.2-1.21.11.6-1.31.51.7-1.3-0.5
One hour access (0.3 mA shock)0.30.40.80.2-0.8-0.70.80.8-0.9-0.60.6-0.5-0.40.4-0.4
Compulsive drug intake0.20.21.31.10.30.30.0-0.20.00.2-0.20.40.6-0.4-0.6
One hour access (shock baseline)0.10.10.2-0.4-0.5-0.40.30.4-0.4-0.20.3-0.4-0.30.30.0
Social response proportion0.30.30.4-0.50.60.5-0.6-0.50.50.4-0.60.60.6-0.5-0.2
Social responses0.20.21.6-0.40.30.2-0.2-0.1-0.10.3-0.3-0.30.30.81.3
Social time1.31.710.3-3.20.80.6-1.5-1.21.30.8-1.3-0.00.6-0.41.1
Soleus weight0.72.113.83.70.30.40.60.1-0.40.30.41.90.1-1.1-2.4
Bone: stiffness0.81.25.41.10.40.5-0.2-0.60.60.3-0.31.50.6-1.9-2.3
Tibialis anterior weight1.03.426.55.2-0.6-0.41.71.3-1.6-0.31.71.1-0.70.5-1.3
Time to tail flick, vehicle, before self-admin0.40.41.8-1.30.10.4-0.7-0.60.70.2-0.7-0.40.2-0.10.7
Time to tail flick, vehicle, after self-admin3.03.35.71.2-1.7-1.81.61.8-1.7-1.71.9-2.1-1.92.41.5
Time to tail flick, test, before self-admin3.33.24.8-0.6-2.2-2.12.02.1-2.0-2.02.0-1.7-2.01.4-0.2
Time to tail flick, test, after self-admin0.80.82.9-1.7-0.8-0.80.20.4-0.2-0.90.4-1.3-1.10.91.1
Delta time to tail flick, vehicle, before/after SA3.63.65.91.2-1.7-2.01.92.1-2.1-1.82.1-1.9-1.92.41.3
Delta time to tail flick, test, before/after SA0.30.30.7-0.80.40.3-0.7-0.60.70.4-0.5-0.20.1-0.10.7
Tibia length0.30.91.70.6-1.2-1.11.01.1-1.0-1.31.2-0.6-0.50.5-0.6
Ambulatory time before self-admin0.20.20.30.2-0.4-0.40.40.5-0.5-0.30.4-0.4-0.50.50.3
Ambulatory time after self-admin0.40.43.31.80.10.10.40.2-0.30.10.30.70.2-0.3-0.8
Bone: tissue strength1.01.02.3-0.3-0.9-0.80.81.1-1.0-0.80.8-1.2-1.01.51.2
Total heroin consumption1.82.111.73.40.20.40.80.2-0.30.20.61.90.4-1.4-2.7
Bone: trabecular number1.21.93.0-0.41.71.7-1.7-1.71.71.5-1.71.01.3-1.00.4
Bone: trabecular spacing2.02.64.10.2-2.0-2.02.01.9-2.0-1.81.8-1.0-1.50.7-1.2
Bone: trabecular thickness1.51.82.81.01.61.6-1.2-1.41.31.3-1.21.71.7-1.3-0.5
Bone: trabecular tissue density4.76.69.7-0.02.93.0-2.7-2.82.72.8-2.82.73.1-2.5-0.4
Water consumed over 24 hours0.30.31.61.3-0.2-0.20.50.5-0.6-0.30.5-0.1-0.70.80.5
Number of responses in last shaping day1.11.22.51.61.11.2-0.7-0.80.81.2-0.71.61.0-1.1-0.8