LOC102549494

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC102549494 0.3 0.1 0.0e+00 0.19 0.28 0.26 0.26 1.7e-10 2.6e-15 4.1e-14 2.0e-14
2 Liver gene expression LOC102549494 0.02 0.02 6.8e-03 0.01 0.01 0.01 0.01 1.2e-02 7.0e-03 2.1e-02 3.5e-02
3 OFC gene expression LOC102549494 0.69 0.11 5.0e-13 0.48 0.49 0.52 0.52 3.7e-13 2.1e-13 2.3e-14 2.9e-14
4 Brain gene expression LOC102549494 0.37 0.1 0.0e+00 0.24 0.29 0.31 0.32 4.8e-22 2.2e-27 6.4e-29 4.9e-30
5 pVTA gene expression LOC102549494 0.15 0.09 1.0e-04 0.06 0.08 0.07 0.01 1.7e-03 2.3e-04 8.0e-04 1.4e-01
6 Adipose mRNA stability LOC102549494 0.07 0.04 5.0e-06 0.01 0.03 0.04 0.03 8.5e-03 3.5e-04 7.4e-05 1.5e-04
7 PL gene expression LOC102549494 0.3 0.1 0.0e+00 0.23 0.25 0.27 0.27 2.4e-25 1.8e-27 3.4e-29 2.8e-29
8 Adipose isoform ratio XR_595225.2 0.11 0.08 1.7e-06 0.03 0.02 0.01 0.01 2.2e-04 4.1e-03 1.1e-02 5.7e-02
9 Adipose intron excision ratio chr12_4999737_4999823 0.04 0.03 1.3e-03 0 0 -0 0 1.5e-01 1.4e-01 6.0e-01 1.7e-01
10 Brain intron excision ratio chr12_5001884_5002075 0.03 0.02 1.3e-03 0.04 0.03 0.03 0.04 1.9e-04 4.2e-04 1.1e-03 3.2e-04
11 LHb gene expression LOC102549494 0.31 0.13 4.5e-05 0.2 0.18 0.17 0.17 1.6e-05 5.4e-05 9.0e-05 8.2e-05
12 Adipose gene expression LOC102549494 0.69 0.09 0.0e+00 0.46 0.38 0.49 0.22 6.8e-57 6.2e-44 1.0e-61 5.3e-24
13 NAcc gene expression LOC102549494 0.23 0.1 0.0e+00 0.2 0.19 0.2 0.2 4.0e-23 3.2e-21 7.6e-23 4.4e-23
14 Brain intron excision ratio chr12_4999903_5001504 0.18 0.07 1.1e-16 0.15 0.18 0.18 0.18 5.0e-14 1.2e-16 6.0e-17 1.4e-16
15 Adipose isoform ratio XR_005491684.1 0.18 0.1 9.4e-12 0.06 0.06 0.07 0.04 8.9e-07 7.0e-07 8.4e-08 4.5e-05
16 Brain isoform ratio XR_595225.2 0.05 0.03 1.1e-03 0.03 0.03 0.02 0.03 3.8e-04 1.3e-03 9.5e-03 1.5e-03
17 Brain intron excision ratio chr12_5001884_5003419 0.04 0.02 3.7e-04 0.03 0.03 0.03 0.03 7.7e-04 6.2e-04 1.8e-03 1.5e-03
18 Brain alternative TSS XR_595226.2 0.1 0.06 1.4e-04 0.04 0.03 0.02 0.04 1.2e-04 7.5e-04 3.3e-03 1.9e-04
19 Adipose alternative polyA XR_595226.2 0.02 0.02 9.7e-03 0 0 -0 -0 7.4e-02 1.0e-01 3.9e-01 7.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density11.819.724.54.44.4-4.74.64.3-4.84.9-4.93.74.6-4.6-3.9-4.6-4.84.6-4.24.34.0-3.7
Area under the delay curve1.41.42.5-1.4-1.51.2-1.2-1.61.1-1.00.7-1.4-1.21.10.80.91.1-1.11.1-1.3-1.31.4
BMI with tail3.411.014.13.13.3-3.53.63.4-3.33.5-3.82.63.4-3.5-3.2-3.3-3.62.4-3.33.43.5-2.6
BMI without tail0.51.13.91.61.8-1.01.41.7-0.90.4-0.42.00.2-0.2-0.1-0.2-0.9-0.30.10.41.50.5
Body weight15.263.683.08.99.1-8.38.78.8-8.48.0-7.88.47.3-7.5-7.6-7.2-8.27.5-7.27.48.0-6.5
Weight adjusted by age1.41.54.91.51.3-1.31.80.8-2.21.2-1.11.51.0-0.6-1.5-1.2-0.81.3-1.20.40.8-0.5
Bone surface11.019.425.54.54.5-4.74.84.3-5.04.8-4.93.94.6-4.5-3.9-4.5-4.74.3-4.04.13.9-3.5
Bone volume10.517.924.43.93.9-4.54.24.0-4.44.7-4.93.14.7-4.6-3.8-4.6-4.74.0-4.24.33.8-3.5
Breakpoint value in progressive ratio session0.60.61.7-0.2-0.10.9-0.6-0.10.3-1.21.3-0.1-1.30.91.21.20.4-0.21.2-0.30.40.5
Number of licking bursts1.11.33.51.41.0-1.41.31.0-1.11.0-0.71.91.1-1.0-1.8-1.20.50.9-1.1-0.3-0.8-0.6
Context. condit. distance diff. score2.63.26.72.02.3-1.61.02.2-1.71.4-1.31.71.5-1.5-0.8-1.5-2.51.9-1.42.32.6-1.6
Locomotion velocity, session 11.31.43.0-0.8-0.91.4-0.8-1.30.5-1.11.4-0.7-1.71.70.91.71.1-0.61.6-1.2-0.80.8
Locomotion distance, session 10.81.13.1-1.2-1.40.9-0.5-1.80.3-0.80.7-1.3-0.91.00.50.91.0-0.51.0-1.4-1.21.3
Locomotion velocity, session 20.70.93.2-0.4-0.70.7-0.0-1.1-0.1-0.60.9-0.1-1.21.2-0.11.21.50.11.0-1.5-1.80.5
Locomotion distance, session 20.81.14.3-0.6-1.20.60.2-1.6-0.3-0.40.5-0.5-0.91.0-0.20.91.7-0.01.0-2.0-2.11.2
Locomotion velocity, session 30.50.61.10.60.5-0.70.50.5-0.90.8-0.80.30.9-0.9-1.0-0.9-0.91.0-0.90.90.3-0.7
Locomotion distance, session 30.10.10.4-0.0-0.1-0.2-0.0-0.3-0.60.2-0.3-0.20.4-0.2-0.3-0.4-0.40.2-0.20.0-0.20.3
Stereotopy head waving bouts, day 30.50.61.51.11.1-0.81.00.8-0.90.5-0.61.20.4-0.50.2-0.4-0.80.30.10.11.20.3
Stereotopy head waving duration, day 30.00.00.3-0.1-0.10.00.0-0.20.3-0.1-0.1-0.2-0.1-0.10.50.10.0-0.10.2-0.20.40.4
Locomotion velocity, session 70.30.31.0-0.8-0.90.5-0.6-1.0-0.1-0.10.3-0.9-0.20.2-0.00.20.50.90.0-0.5-0.70.3
Locomotion distance, session 70.10.20.4-0.5-0.60.5-0.7-0.6-0.0-0.30.2-0.6-0.30.40.20.30.20.60.1-0.4-0.30.4
Stereotopy head waving bouts, day 73.43.95.3-1.9-1.92.0-2.1-2.11.9-2.32.3-1.7-1.92.01.91.91.9-1.62.0-2.0-1.92.0
Stereotopy head waving duration, day 72.02.44.0-1.5-1.61.4-1.5-1.71.5-1.71.9-1.3-1.41.41.21.42.0-1.11.4-1.7-2.01.3
Locomotion velocity, session 80.50.61.7-0.3-0.30.9-0.4-0.60.1-0.91.2-0.1-1.31.30.71.30.7-0.21.0-0.8-0.50.7
Locomotion distance, session 80.91.44.11.41.3-1.21.20.9-2.01.2-1.01.20.9-0.9-1.0-0.9-1.21.7-0.70.81.0-0.8
Degree of sensitization distance1.01.11.9-1.0-1.11.2-0.9-1.10.9-0.91.0-0.8-1.31.20.91.31.4-0.51.0-1.2-0.90.6
Degree of sensitization stereotypy2.52.84.9-1.6-1.61.7-2.0-1.61.8-2.02.2-1.4-1.51.71.41.51.8-1.21.6-1.4-1.81.2
Conditioned locomotion0.50.63.40.50.7-0.80.70.5-0.40.8-1.10.10.6-0.70.2-0.5-1.4-0.70.10.71.80.3
Cocaine response after cond. corrected0.50.62.1-0.8-0.50.7-1.2-0.21.4-0.80.6-0.9-0.40.41.00.4-0.1-1.50.50.20.40.8
Cocaine response after cond. not corrected0.60.71.7-0.9-0.50.9-1.3-0.21.3-0.80.6-1.1-0.70.71.10.6-0.4-1.10.40.40.80.7
Cocaine response before conditioning0.20.31.40.30.40.00.30.2-0.80.3-0.20.0-0.10.3-0.20.2-0.71.2-0.50.70.8-0.7
Saline control response0.60.84.01.51.2-0.81.20.6-2.00.30.11.80.10.0-0.2-0.0-0.01.0-0.0-0.50.10.3
Bone: connectivity density12.619.829.84.84.7-4.75.04.4-5.54.8-4.74.34.3-4.3-3.9-4.3-4.54.9-3.73.83.9-3.5
Bone: cortical apparent density0.10.10.5-0.3-0.30.1-0.4-0.10.70.2-0.1-0.40.1-0.2-0.2-0.10.1-0.2-0.30.2-0.2-0.7
Bone: cortical area4.36.59.02.42.4-2.92.72.5-2.72.8-3.02.13.0-2.9-2.2-2.9-2.71.9-2.42.42.3-2.0
Bone: cortical porosity1.21.32.7-1.0-1.01.1-1.1-1.10.9-1.21.3-0.8-1.11.11.21.11.0-1.11.7-1.3-1.01.4
Bone: cortical porosity1.61.72.6-1.2-1.31.2-1.3-1.41.0-1.41.4-1.0-1.21.31.41.21.3-1.31.6-1.5-1.41.5
Bone: cortical thickness3.45.67.42.32.3-2.62.52.4-2.42.6-2.72.02.7-2.7-1.9-2.6-2.61.6-2.12.32.3-1.9
Bone: cortical thickness0.30.30.80.80.8-0.60.80.7-0.80.5-0.50.90.5-0.60.3-0.4-0.5-0.3-0.10.10.50.3
Bone: cortical tissue density0.10.10.7-0.4-0.40.2-0.6-0.20.80.00.0-0.4-0.0-0.0-0.10.10.2-0.3-0.20.1-0.2-0.6
Condit. Reinf. active minus inactive responses1.21.32.60.70.6-1.41.20.5-1.01.4-1.40.31.6-1.6-1.5-1.5-0.80.7-1.41.00.7-1.3
Condit. Reinf. active-inactive response ratio1.01.12.40.50.5-1.31.00.6-0.61.2-1.20.21.5-1.5-1.1-1.5-0.70.6-1.31.00.8-1.2
Condit. Reinf. active responses0.10.20.60.20.2-0.60.40.20.00.4-0.40.10.5-0.6-0.8-0.5-0.3-0.0-0.50.40.3-0.4
Condit. Reinf. inactive responses1.11.42.3-0.9-0.91.3-1.3-0.91.5-1.31.3-0.7-1.51.50.81.51.0-1.11.1-1.0-0.91.1
Incentive salience index mean0.40.51.20.20.3-0.90.80.3-0.60.9-1.0-0.11.0-1.1-0.7-1.0-0.8-0.0-0.70.70.8-0.5
Condit. Reinf. lever presses0.20.21.1-0.5-0.20.3-0.3-0.20.3-0.2-0.0-0.7-0.30.20.60.2-0.6-1.10.50.20.80.6
Condit. Reinf. active minus inactive responses0.10.20.70.40.2-0.10.40.0-0.8-0.10.20.7-0.20.20.10.20.40.50.5-0.7-0.40.5
Condit. Reinf. active-inactive response ratio0.50.51.7-0.1-0.50.5-0.1-0.8-0.6-0.50.60.1-0.80.80.40.91.00.00.9-1.3-1.00.9
Condit. Reinf. active responses0.30.41.30.80.7-0.60.80.4-1.20.4-0.21.00.4-0.4-0.5-0.4-0.31.0-0.1-0.00.10.0
Condit. Reinf. inactive responses0.60.71.20.90.9-0.90.80.8-0.80.7-0.60.80.9-0.9-0.7-0.9-1.11.1-0.70.90.9-0.6
Condit. Reinf. lever presses1.31.73.11.11.1-1.51.31.0-1.41.4-1.60.71.6-1.6-1.0-1.6-1.81.0-1.11.31.5-0.7
Condit. Reinf. lever reinforcers received0.20.31.30.70.5-0.70.80.3-1.10.4-0.30.80.5-0.5-0.6-0.5-0.11.1-0.2-0.2-0.1-0.1
Conditioned reinforcement - actives1.01.04.11.61.8-0.50.51.7-1.10.20.52.0-0.20.3-0.3-0.1-0.61.2-0.10.81.0-0.9
Conditioned reinforcement - inactives0.10.10.40.00.10.4-0.40.3-0.1-0.50.60.3-0.60.50.30.20.10.30.00.1-0.30.4
Conditioned locomotion0.50.62.21.11.20.10.21.1-0.7-0.51.01.5-0.71.00.50.4-0.10.40.60.20.70.1
Patch foraging indifference point 0 sec2.84.68.11.61.7-2.52.01.6-1.62.4-2.61.12.8-2.8-2.0-2.7-2.51.7-2.42.22.0-1.5
Patch foraging indifference point AUC0.91.01.81.21.2-1.31.11.1-1.31.1-1.11.21.0-1.0-0.7-1.0-1.20.5-0.40.70.9-0.4
Delay disc. indifference point, 0s delay0.20.20.7-0.1-0.4-0.00.1-0.6-0.40.4-0.7-0.40.2-0.3-0.9-0.40.00.7-0.5-0.0-0.7-0.4
Delay disc. indifference point, 16s delay0.80.82.0-1.2-1.20.8-1.3-1.01.4-0.80.4-1.1-0.60.50.70.50.7-0.60.8-0.7-1.30.9
Delay disc. indifference point, 2s delay2.02.24.3-1.9-1.91.7-1.7-2.11.4-1.41.1-2.1-1.41.41.11.11.2-1.30.8-1.2-1.41.2
Delay disc. indifference point, 24s delay1.41.33.6-1.3-1.51.2-1.2-1.50.9-1.00.9-1.2-1.11.00.50.81.4-0.50.7-1.3-1.90.9
Delay disc. indifference point, 4s delay1.21.33.0-1.5-1.51.2-1.2-1.61.0-0.80.3-1.7-1.00.81.00.80.6-1.21.2-0.9-0.81.4
Delay disc. indifference point, 8s delay0.40.41.3-0.7-0.70.5-0.4-0.80.4-0.40.2-0.6-0.60.50.50.40.7-1.10.6-0.8-0.51.0
Indifference point function ln k0.20.21.10.40.4-0.30.20.40.20.10.20.70.2-0.3-0.7-0.20.21.0-0.50.1-0.1-0.9
Indifference point function log k0.20.21.10.40.4-0.30.20.40.20.10.20.70.2-0.3-0.7-0.20.21.0-0.50.1-0.1-0.9
Patch foraging total patch changes 0 sec2.84.57.81.61.7-2.51.91.7-1.52.3-2.61.12.8-2.8-1.9-2.6-2.51.6-2.32.22.1-1.4
Patch foraging total patch changes 12 sec4.15.39.61.71.8-2.52.21.8-2.22.7-3.11.02.8-2.8-1.9-2.7-3.11.5-2.22.52.1-1.6
Patch foraging total patch changes 18 sec1.11.43.00.81.0-1.40.91.0-0.91.1-1.40.51.7-1.6-0.7-1.6-1.70.6-1.01.31.3-0.5
Patch foraging total patch changes 24 sec1.41.73.21.01.1-1.61.11.0-1.11.3-1.60.51.8-1.7-0.9-1.7-1.80.6-1.31.31.5-0.2
Patch foraging total patch changes 6 sec1.32.04.31.21.4-1.71.41.4-1.11.5-1.80.81.7-1.6-0.8-1.7-2.10.5-1.21.51.9-0.4
Patch foraging time to switch 0 sec2.13.26.6-2.3-2.22.1-2.3-2.12.1-1.71.4-2.6-1.61.81.81.61.2-1.51.5-1.0-1.01.0
Patch foraging water rate 0 sec3.96.210.03.13.1-2.73.13.0-2.92.6-2.33.22.1-2.3-2.2-2.0-2.32.2-2.02.02.0-1.5
Patch foraging water rate 12 sec0.81.22.71.41.1-1.31.51.1-1.51.0-0.71.60.9-1.1-1.6-0.8-0.01.2-1.20.2-0.1-0.7
Patch foraging water rate 18 sec0.30.51.0-0.2-0.30.5-0.1-0.30.3-0.71.00.1-0.90.70.50.91.0-0.50.9-1.0-0.81.0
Patch foraging water rate 24 sec1.11.64.81.91.7-1.71.91.5-1.61.1-0.72.21.1-1.1-0.8-0.9-0.61.0-0.30.10.8-0.2
Patch foraging water rate 6 sec1.72.44.21.61.5-1.71.81.5-2.01.7-1.31.51.5-1.6-1.8-1.4-1.11.8-1.51.30.8-1.5
Seeking ratio, delayed vs. immediate footshock2.02.33.6-1.5-1.41.8-1.9-1.21.9-1.61.6-1.5-1.81.81.71.81.3-1.71.1-0.8-0.81.0
Distance traveled before self-admin0.20.30.9-0.8-0.70.5-0.9-0.40.9-0.40.4-0.9-0.10.10.4-0.00.40.00.10.0-0.5-0.0
Distance traveled after self-admin0.20.20.60.30.3-0.50.40.3-0.50.3-0.20.40.5-0.5-0.8-0.5-0.40.4-0.80.30.40.0
Extensor digitorum longus weight3.011.920.14.14.4-3.42.94.5-2.53.1-3.04.23.0-2.9-3.0-3.0-3.83.3-3.13.63.8-3.0
Bone: elastic displacement0.70.81.6-0.3-0.30.8-0.5-0.40.6-0.91.00.1-1.21.00.91.30.8-0.81.2-1.1-0.91.2
Bone: elastic work2.73.46.52.42.4-1.92.52.2-2.62.0-1.82.61.4-1.5-1.4-1.4-1.71.5-1.11.21.5-1.0
Bone: endosteal estimation0.71.53.21.61.5-1.51.51.3-1.61.3-1.21.81.2-1.1-1.4-1.2-0.71.4-0.90.50.5-0.7
Bone: endosteal perimeter1.73.54.52.02.0-2.12.11.9-2.12.0-2.01.92.0-2.0-1.7-2.0-1.81.6-1.61.51.8-1.1
Epididymis fat weight2.14.98.21.61.8-2.21.62.1-1.22.2-2.51.22.6-2.5-2.6-2.5-2.22.1-2.92.61.9-2.7
Delta time in closed arm before/after self-admin0.30.31.20.60.5-0.50.50.7-0.50.5-0.20.90.3-0.4-0.4-0.40.30.9-0.20.2-0.1-1.1
Delta time in open arm before/after self-admin4.84.68.0-2.7-2.52.3-2.5-2.52.4-2.31.9-2.8-1.91.72.01.81.4-2.51.5-1.4-1.82.3
Diff in mean of infusions in LGA sessions0.30.31.1-0.3-0.20.8-0.6-0.00.4-0.70.7-0.3-1.10.70.80.80.2-0.20.8-0.1-0.10.5
Delay discount exponential model param1.71.82.71.61.6-1.41.41.6-1.31.2-0.81.51.4-1.2-1.0-1.0-1.31.3-1.21.41.4-1.5
Extinction: sum of active levers before priming0.30.31.20.00.1-0.3-0.00.10.00.1-0.1-0.20.5-0.7-0.7-0.6-0.40.4-1.10.70.7-0.8
Active lever presses in extinction session 62.22.24.21.31.4-1.31.11.5-1.11.3-1.31.21.3-1.5-1.8-1.6-1.41.7-1.91.71.2-2.0
Bone: final force2.23.67.52.32.2-2.02.52.0-2.72.2-2.12.21.7-1.6-1.5-1.6-1.71.3-1.61.31.6-1.1
Bone: final moment1.93.26.22.12.0-1.92.31.9-2.52.0-2.02.11.6-1.5-1.5-1.5-1.61.2-1.51.21.4-1.0
Food consumed during 24 hour testing period1.21.43.4-0.6-0.61.1-1.1-0.60.9-1.41.4-0.3-1.31.41.71.20.9-1.61.6-1.2-0.41.8
Glucose0.10.10.7-0.3-0.40.2-0.1-0.20.50.00.0-0.3-0.10.1-0.60.10.40.3-0.40.1-0.8-0.6
Heart weight0.10.20.70.50.2-0.40.5-0.0-0.50.10.00.80.20.0-0.6-0.10.60.3-0.2-0.7-0.80.2
Delay discount hyperbolic model param1.92.03.11.61.7-1.51.41.8-1.31.2-0.91.61.4-1.3-1.0-1.1-1.31.4-1.21.41.5-1.5
Intermittent access intake day 1-15 change0.20.21.10.70.7-0.30.60.5-1.10.10.10.9-0.00.1-0.30.0-0.30.60.20.10.20.2
Intermittent access intake escalation0.30.31.30.80.8-0.40.80.6-1.10.2-0.00.90.0-0.1-0.30.0-0.30.40.20.00.30.3
Intermittent access intake escalation 20.10.10.40.10.1-0.20.3-0.0-0.6-0.00.10.2-0.00.00.10.1-0.0-0.20.3-0.20.10.6
Intermitt. access day 1 inactive lever presses0.10.10.50.30.2-0.10.10.30.30.1-0.20.70.0-0.2-0.60.00.30.6-0.1-0.3-0.7-0.0
Intermitt. access day 15 inactive lever presses0.60.72.1-1.1-0.81.1-1.4-0.41.5-0.90.7-1.2-0.70.80.80.50.1-0.80.20.2-0.10.5
Intermitt. access escalation Index0.10.10.30.20.0-0.30.4-0.1-0.30.6-0.60.20.4-0.3-0.4-0.00.10.30.0-0.2-0.5-0.4
Intermittent access day 1 total infusions3.13.66.3-1.8-1.72.2-2.2-1.71.7-2.12.1-1.7-2.32.22.52.01.4-1.72.2-1.4-1.11.7
Intermittent access day 15 total infusions1.51.73.8-0.7-0.71.4-1.1-0.90.2-1.51.7-0.5-1.91.81.81.70.9-0.91.9-1.1-0.61.6
Intermittent access terminal intake (last 3 days)2.12.34.6-1.3-1.21.7-1.6-1.20.8-1.72.0-1.2-1.91.92.11.71.0-1.32.0-1.1-0.71.6
Intermittent access total infusions4.14.67.9-1.9-1.82.4-2.4-1.91.6-2.42.6-1.7-2.62.52.82.41.5-1.72.6-1.7-1.22.1
Intermittent access day 1 locomotion3.73.95.6-2.0-2.02.3-2.2-2.01.7-2.02.2-1.9-2.32.42.32.11.8-1.52.2-1.6-1.61.3
Intermittent access day 15 total locomotion2.22.45.0-0.9-0.91.6-1.5-1.11.2-1.82.2-0.5-2.12.11.71.81.6-1.01.8-1.5-1.21.5
Intermittent access total locomotion4.24.87.4-1.9-1.92.5-2.4-2.01.9-2.52.7-1.6-2.72.72.42.42.1-1.42.4-1.9-1.91.8
Intermittent access standard deviation0.10.10.30.30.3-0.20.10.1-0.5-0.00.20.2-0.00.1-0.00.0-0.30.50.20.20.30.1
Left kidney weight9.626.937.36.16.0-5.45.65.9-5.95.1-4.96.14.9-4.7-5.1-4.8-4.75.4-4.54.44.0-4.4
Right kidney weight10.730.038.86.26.1-5.85.96.0-5.85.6-5.26.15.2-5.1-5.6-5.1-4.75.6-5.14.74.4-5.2
Cocaine induced anxiety0.20.31.1-0.3-0.00.5-0.60.10.6-0.50.4-0.5-0.50.70.50.5-0.3-0.70.10.51.0-0.2
Post-drug Anxiety6.06.69.1-2.7-2.62.9-2.8-2.52.6-2.82.7-2.7-2.93.02.62.92.2-2.72.4-1.9-1.31.7
Baseline Anxiety3.73.96.7-2.5-2.62.1-2.2-2.52.1-1.81.7-2.4-1.71.51.41.72.2-1.41.4-1.8-2.51.0
Tail length1.34.115.13.33.4-1.92.42.9-2.51.2-0.83.90.7-0.7-0.9-0.6-1.81.4-0.30.92.3-0.1
Length with tail10.739.161.87.87.9-6.46.77.3-7.06.0-5.47.75.1-5.2-5.7-5.0-6.36.5-4.95.46.2-4.8
Length without tail19.442.449.86.66.6-6.56.46.4-6.76.8-6.75.76.4-6.5-6.8-6.3-6.77.1-6.66.56.0-6.4
Times rat made contact with spout0.30.31.90.80.7-0.10.30.5-0.3-0.30.71.4-0.50.4-0.60.40.9-0.2-0.1-0.7-0.50.1
Lifetime Intake3.64.07.6-1.9-1.72.3-2.4-1.81.8-2.32.4-1.8-2.42.32.82.21.3-1.62.2-1.3-0.91.7
Liver weight, left6.410.212.63.03.0-3.43.22.9-3.33.4-3.52.53.4-3.5-3.3-3.5-3.23.3-3.43.02.9-2.8
Liver weight, right8.013.318.44.34.2-3.94.13.9-3.73.9-3.64.03.2-3.3-4.0-3.1-3.33.7-3.53.13.2-3.2
Locomotor activity0.71.13.71.51.4-1.11.41.4-1.40.8-0.41.90.7-0.6-1.1-0.8-0.31.1-0.60.30.3-0.4
Locomotor testing distance0.40.71.91.21.1-0.91.01.2-0.80.7-0.41.40.8-0.6-1.1-0.7-0.40.6-0.70.50.4-0.3
Locomotor testing rearing0.10.10.3-0.0-0.1-0.20.2-0.2-0.40.2-0.1-0.10.4-0.2-0.6-0.30.10.5-0.4-0.0-0.40.2
Locomotion in novel chamber1.11.33.1-0.2-0.30.9-0.3-0.60.6-1.21.50.5-1.51.61.11.51.5-0.91.6-1.8-1.01.4
Locomotion in novel chamber post-restriction0.60.73.31.11.1-0.10.90.9-0.1-0.30.61.8-0.90.60.51.00.4-0.90.9-0.90.50.9
Fecal boli incidents, locomotor time 11.01.15.31.31.2-0.91.00.9-1.70.7-0.51.40.6-0.7-1.1-0.6-0.72.3-0.40.70.2-1.3
Change in fecal boli incidents, locomotor task0.80.83.0-1.0-0.90.8-1.0-0.61.4-0.80.5-0.9-0.60.70.90.70.6-1.70.5-0.5-0.50.7
Time >=10cm from walls, locomotor time 10.20.21.3-0.8-0.80.3-0.5-0.70.30.0-0.3-1.10.1-0.30.5-0.20.1-0.5-0.10.10.3-0.1
Bouts of movement, locomotor time 10.60.71.81.11.2-1.01.01.4-0.90.6-0.61.40.6-0.7-0.2-0.8-0.7-0.4-0.30.50.90.2
Total resting periods, locomotor time 10.70.71.91.11.2-1.11.01.4-0.70.6-0.71.30.7-0.9-0.2-1.0-0.8-0.4-0.30.60.90.3
Rest time, locomotor task time 10.20.21.30.30.40.10.00.3-0.1-0.40.40.4-0.40.40.40.5-0.3-0.81.1-0.10.11.0
Distance moved, locomotor task time 10.10.20.70.1-0.1-0.30.4-0.1-0.30.5-0.30.10.3-0.4-0.5-0.40.20.6-0.7-0.1-0.2-0.8
Vertical activity count, locomotor time 11.11.12.01.10.9-1.11.41.0-1.11.4-1.21.21.0-1.2-1.0-1.0-0.41.1-1.30.60.5-1.2
Time >=10cm from walls, locomotor time 21.61.72.90.90.9-1.41.20.7-1.71.5-1.50.51.6-1.4-1.6-1.7-1.31.5-1.31.20.9-1.2
Bouts of movement, locomotor time 24.64.97.52.22.0-2.52.62.0-2.32.6-2.72.02.4-2.6-2.5-2.4-1.91.6-2.31.71.5-1.8
Total resting periods, locomotor time 24.54.87.42.12.0-2.42.42.0-2.12.5-2.71.92.4-2.6-2.4-2.3-2.01.5-2.41.81.7-1.9
Rest time, locomotor task time 20.60.72.2-0.7-0.30.8-0.9-0.31.3-1.00.6-0.7-0.80.51.11.0-0.2-1.51.0-0.00.81.0
Distance moved, locomotor task time 20.80.92.11.00.6-1.21.40.5-1.51.0-0.71.21.0-0.9-1.2-1.20.31.0-1.0-0.2-0.4-0.8
Vertical activity count, locomotor time 22.72.96.12.21.9-1.92.21.9-2.41.8-1.42.51.5-1.5-1.5-1.5-0.71.9-1.40.70.6-1.4
Light reinforcement 11.11.92.9-1.7-1.71.6-1.7-1.71.4-1.51.6-1.7-1.21.41.21.01.4-0.70.6-1.0-1.50.9
Light reinforcement 20.30.30.8-0.7-0.70.7-0.6-0.50.6-0.60.5-0.6-0.50.60.90.50.7-0.50.3-0.4-0.40.3
Bone: marrow area0.71.43.11.61.5-1.41.41.2-1.51.2-1.11.81.1-1.1-1.3-1.1-0.71.3-0.90.50.5-0.7
Bone: maximum diameter2.85.16.72.32.3-2.62.62.2-2.62.4-2.52.02.6-2.6-1.9-2.5-2.21.6-1.91.92.0-1.5
Bone: maximum force3.66.19.42.62.5-2.82.92.4-3.12.8-3.02.42.6-2.5-2.0-2.6-2.61.8-2.22.02.1-1.6
Bone: maximum moment3.25.48.02.52.4-2.62.72.3-2.82.7-2.82.22.5-2.4-2.0-2.4-2.41.7-2.21.91.9-1.5
Mean time between licks in bursts1.11.52.5-1.4-1.61.1-0.8-1.51.1-0.90.6-1.4-1.01.11.10.91.3-1.41.5-1.4-1.61.2
Mean num. licks in bursts0.80.92.2-0.8-0.51.2-1.0-0.60.8-1.11.0-0.8-1.31.21.51.40.1-1.11.0-0.30.40.8
Cd content in liver1.61.83.6-1.1-1.21.3-0.9-1.21.1-1.21.3-0.7-1.51.61.01.51.9-1.41.4-1.6-1.81.0
Co content in liver1.82.13.8-0.9-0.71.5-1.3-0.71.3-1.71.8-0.5-1.71.71.81.71.2-1.51.9-1.3-0.52.0
Cu content in liver1.92.34.11.41.4-1.61.61.4-1.11.6-1.61.31.6-1.7-2.0-1.6-1.21.5-1.51.50.8-1.9
Fe content in liver12.014.417.43.73.8-3.83.74.0-3.54.0-4.03.13.9-3.9-3.7-3.9-3.83.4-4.14.23.6-3.9
K content in liver0.40.40.8-0.6-0.60.6-0.5-0.70.5-0.70.5-0.7-0.60.50.80.60.2-0.70.7-0.5-0.20.9
Mg content in liver0.60.61.0-0.5-0.50.9-0.7-0.60.4-1.01.0-0.3-1.01.00.91.00.6-0.40.9-0.7-0.70.9
Mn content in liver0.30.41.5-0.5-0.80.4-0.3-1.1-0.2-0.40.6-0.5-0.30.4-0.00.30.90.90.3-0.8-1.2-0.3
Na content in liver0.20.20.70.40.3-0.30.40.1-0.60.6-0.60.10.3-0.4-0.1-0.3-0.60.8-0.20.30.6-0.3
Rb content in liver0.70.83.3-1.5-1.40.9-1.1-1.11.2-0.70.4-1.8-0.30.31.00.30.2-1.10.4-0.1-0.40.3
Se content in liver1.72.04.81.01.2-1.20.91.4-0.81.3-1.60.41.5-1.5-0.8-1.5-2.21.0-1.32.12.2-1.6
Sr content in liver0.10.10.60.60.6-0.40.50.4-0.30.10.10.70.1-0.1-0.3-0.1-0.00.0-0.1-0.10.5-0.0
Zn content in liver3.64.06.82.52.5-2.12.22.5-1.61.9-1.72.61.6-1.7-2.4-1.6-1.52.0-1.91.81.5-2.0
Bone: minimum diameter0.10.20.40.1-0.1-0.50.4-0.1-0.50.4-0.6-0.00.7-0.6-0.4-0.7-0.00.4-0.2-0.0-0.50.1
Time in familiar zone, hab. session 10.40.41.10.1-0.1-0.70.2-0.1-0.50.7-0.5-0.11.1-1.0-0.8-1.1-0.20.8-0.90.3-0.2-0.7
Time in novel zone, hab. session 10.30.30.80.70.7-0.30.70.7-0.40.2-0.10.90.0-0.0-0.9-0.0-0.10.8-0.40.30.1-0.5
Total zone transitions, hab. session 11.62.35.2-1.4-1.71.3-0.6-2.30.1-1.31.3-1.3-1.61.51.01.61.7-0.71.9-2.3-1.81.7
Total locomotion distance, hab. session 10.60.82.8-1.2-1.40.7-0.4-1.7-0.4-0.50.3-1.6-0.50.40.70.50.3-0.21.0-1.0-0.81.3
Locomotion velocity, hab. session 11.92.76.0-2.1-2.21.7-1.3-2.40.6-1.31.0-2.4-1.31.21.71.31.0-1.42.0-1.6-1.42.0
Time in familiar zone, hab. session 21.21.32.90.60.4-1.20.70.7-0.61.1-0.90.41.6-1.5-1.4-1.6-0.41.7-1.51.10.3-1.6
Time in novel zone, hab. session 21.31.32.6-0.9-0.81.3-0.8-0.91.0-1.10.8-0.8-1.51.41.41.50.6-1.61.5-1.1-0.61.4
Total zone transitions, hab. session 20.91.13.3-0.4-0.70.8-0.0-1.2-0.3-1.01.0-0.0-1.31.40.61.31.3-0.21.6-1.8-1.41.4
Total locomotion distance, hab. session 21.51.93.9-1.4-1.51.4-0.8-1.80.3-1.21.1-1.2-1.41.41.41.41.1-1.21.8-1.8-1.42.0
Locomotion velocity, hab. session 21.62.14.3-1.4-1.51.5-0.8-1.80.3-1.31.1-1.2-1.51.51.41.51.2-1.21.9-1.9-1.62.1
Novel to familiar place preference ratio1.31.32.8-0.8-0.91.3-1.2-0.90.9-1.21.5-0.5-1.51.50.51.51.4-0.80.9-1.1-1.70.5
Novelty place preference1.11.23.8-0.9-1.01.2-1.2-1.00.9-1.01.3-0.6-1.21.20.21.21.5-0.50.7-1.0-1.90.2
Time in novel zone, NPP test0.70.72.7-0.6-0.70.9-0.9-0.70.8-0.81.0-0.3-1.01.0-0.11.01.2-0.10.5-0.8-1.6-0.0
Total zone transitions, NPP test0.10.20.90.0-0.2-0.00.3-0.6-0.4-0.20.20.2-0.20.2-0.10.20.50.70.6-1.0-0.70.7
Total locomotion distance, NPP test0.81.02.8-1.1-1.11.0-0.8-1.40.2-0.90.6-1.2-1.00.81.31.00.4-0.61.3-1.1-0.71.7
Locomotion velocity, NPP test1.01.54.1-1.2-1.21.2-0.8-1.40.2-1.20.9-1.1-1.31.11.51.30.7-0.91.6-1.4-0.92.0
Intraocular pressure0.60.82.61.11.4-0.60.41.5-0.60.4-0.41.10.5-0.5-0.3-0.5-1.30.8-0.51.31.6-0.9
Delta distance traveled before/after self-admin0.30.31.10.70.6-0.81.10.2-1.00.5-0.40.80.5-0.4-0.6-0.3-0.50.2-0.4-0.20.40.5
Delta ambulatory time before/after self-admin0.20.20.60.40.3-0.60.80.0-0.60.5-0.50.40.5-0.3-0.8-0.3-0.40.0-0.6-0.10.20.4
Parametrial fat weight0.20.30.80.60.4-0.50.90.4-0.80.8-0.60.60.2-0.5-0.8-0.1-0.10.7-0.80.2-0.0-0.5
Pavlov. Cond. lever latency4.45.610.22.52.3-2.42.22.4-2.12.3-2.32.52.4-2.2-2.8-2.3-1.63.2-2.62.01.0-2.7
Pavlov. Cond. magazine entry latency0.81.13.9-0.3-0.20.7-0.4-0.30.8-1.01.10.0-1.11.21.31.20.7-2.01.5-1.10.11.5
Pavlov. Cond. change in total contacts0.70.81.9-1.0-0.80.8-0.9-1.01.0-0.80.8-1.1-0.80.81.00.80.3-1.41.0-0.6-0.10.9
Pavlov. Cond. index score1.51.85.7-1.1-0.91.2-1.1-0.91.3-1.41.4-1.0-1.41.51.91.40.7-2.41.7-1.10.11.8
Pavlov. Cond. latency score2.02.67.0-1.4-1.11.5-1.3-1.31.5-1.71.6-1.2-1.71.72.11.60.9-2.72.0-1.4-0.12.1
Pavlov. Cond. lever contacts4.24.910.1-2.3-2.02.3-2.1-2.12.1-2.22.1-2.3-2.32.22.72.21.3-3.22.5-1.7-0.62.5
Pavlov. Cond. magazine entry number0.40.51.80.1-0.1-0.50.30.0-0.60.7-0.9-0.30.9-1.0-1.0-0.9-0.41.4-1.10.7-0.2-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.1-0.2-0.3-0.1-0.2-0.30.1-0.1-0.20.4-0.4-0.8-0.40.10.7-0.70.1-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.41.75.6-1.1-0.81.2-1.1-0.91.3-1.31.3-0.9-1.31.41.91.30.6-2.41.7-1.00.21.6
Pavlov. Cond. response bias1.31.54.7-0.8-0.51.1-0.9-0.61.1-1.31.4-0.5-1.41.51.81.40.5-2.21.7-0.90.41.5
Pavlov. Cond. lever latency0.00.10.20.00.10.3-0.40.20.3-0.10.20.2-0.40.3-0.10.40.10.10.00.1-0.3-0.3
Pavlov. Cond. magazine entry latency0.91.02.3-1.4-1.50.8-0.8-1.51.0-0.70.5-1.5-0.40.60.70.41.1-1.10.7-1.0-1.30.4
Pavlov. Cond. change in total contacts0.20.31.10.40.2-0.50.8-0.0-1.00.5-0.30.20.5-0.4-0.6-0.5-0.01.0-0.40.0-0.1-0.5
Pavlov. Cond. index score0.10.20.6-0.6-0.70.2-0.1-0.80.2-0.20.1-0.70.00.10.3-0.00.4-0.40.3-0.5-0.30.3
Pavlov. Cond. latency score0.10.20.7-0.6-0.70.2-0.1-0.80.2-0.20.1-0.80.10.10.3-0.10.3-0.30.3-0.4-0.30.2
Pavlov. Cond. lever contacts0.10.10.5-0.3-0.2-0.20.1-0.2-0.00.1-0.3-0.60.5-0.30.4-0.4-0.5-0.3-0.10.30.70.5
Pavlov. Cond. magazine entry number0.60.71.81.21.3-0.60.71.3-0.90.6-0.51.20.2-0.4-0.4-0.2-1.10.7-0.40.91.3-0.2
Pavlov. Cond. intertrial magazine entries0.20.21.10.80.8-0.30.60.7-0.70.2-0.11.1-0.1-0.0-0.20.2-0.30.20.10.00.40.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.7-0.6-0.70.2-0.0-0.80.1-0.20.2-0.70.00.10.2-0.00.5-0.40.3-0.6-0.50.3
Pavlov. Cond. response bias0.20.21.0-0.8-0.70.2-0.3-0.60.4-0.30.1-1.00.10.10.7-0.1-0.0-0.70.2-0.10.20.7
Time in closed arm before self-admin1.01.12.41.31.2-1.21.30.9-1.61.0-0.81.41.0-0.7-1.4-0.8-0.61.5-0.40.4-0.0-1.0
Time in closed arm after self-admin2.62.76.22.01.6-1.82.01.4-2.01.7-1.32.21.4-1.3-1.9-1.3-0.32.5-0.90.4-0.1-2.2
Time in open arm before self-admin0.50.61.30.90.8-0.70.80.9-0.60.8-0.61.00.5-0.4-0.7-0.7-0.30.6-1.10.60.9-0.9
Time in open arm after self-admin1.31.53.3-1.4-1.21.3-1.4-1.01.3-1.41.3-1.4-1.11.01.51.10.7-1.80.8-0.6-0.41.6
Bone: periosteal estimation2.34.76.32.42.3-2.52.52.2-2.52.3-2.32.42.3-2.3-2.1-2.3-1.91.8-1.91.61.5-1.5
Bone: periosteal perimeter3.35.57.82.22.1-2.62.52.1-2.62.7-2.81.82.8-2.7-2.2-2.7-2.31.8-2.32.11.9-1.8
Bone: post-yield work0.81.13.00.80.9-1.20.70.9-0.81.1-1.30.41.4-1.3-0.6-1.4-1.70.1-0.91.31.5-0.4
Progressive ratio test 1 active lever presses0.20.20.60.20.20.2-0.20.30.2-0.50.70.4-0.60.70.80.40.2-0.30.7-0.20.20.4
Progressive ratio test 1 breakpoint0.30.30.9-0.00.00.4-0.3-0.00.3-0.70.90.2-0.80.90.90.60.4-0.50.9-0.6-0.00.8
Progressive ratio test 1 inactive lever presses0.10.10.80.40.40.00.10.60.20.00.10.9-0.30.30.10.20.20.00.1-0.2-0.20.3
Progressive ratio test 2 active lever presses0.70.82.10.20.30.7-0.40.10.3-1.01.30.7-1.41.11.41.30.5-0.51.4-0.8-0.21.0
Progressive ratio test 2 breakpoint1.41.63.4-0.3-0.31.1-0.8-0.40.7-1.51.80.3-1.91.61.71.61.1-0.91.8-1.3-0.81.5
Progressive ratio test 2 inactive lever presses0.40.42.30.91.00.10.11.0-0.3-0.30.61.5-0.90.70.50.7-0.00.20.6-0.10.20.3
Incentive Sensitization - Responses1.61.63.0-0.8-0.81.2-1.1-0.91.3-1.41.5-0.5-1.61.41.71.51.1-1.11.6-1.3-1.01.5
Incentive Sensitization - Breakpoint1.51.52.8-0.8-0.71.2-1.1-0.81.2-1.41.5-0.4-1.61.41.71.41.0-1.01.6-1.2-1.01.4
Sum of active levers in priming session hrs 5-60.20.20.6-0.3-0.2-0.2-0.2-0.50.10.2-0.4-0.80.2-0.8-0.2-0.2-0.8-0.0-0.50.40.8-0.1
Progressive ratio1.61.84.5-1.3-1.11.6-1.9-1.12.1-1.71.7-1.2-1.61.50.81.41.1-1.30.7-0.7-0.90.8
Food seeking constrained by brief footshock0.20.20.60.20.3-0.60.70.4-0.60.6-0.60.10.5-0.8-0.5-0.5-0.3-0.2-0.30.40.4-0.5
Seeking ratio, punishment vs. effort2.12.66.21.61.4-2.02.31.4-2.52.0-1.81.51.8-1.8-1.1-1.5-1.21.2-0.70.81.1-1.0
Retroperitoneal fat weight1.23.910.20.50.6-1.61.10.9-0.61.9-2.4-0.52.4-2.3-2.8-2.5-2.01.5-3.22.71.7-2.9
Reaction time number correct1.11.72.91.51.4-1.61.61.3-1.51.3-1.11.71.3-1.5-1.4-1.4-0.71.1-1.20.60.6-0.7
Reaction time mean minus median3.03.97.6-1.5-1.42.4-1.9-1.61.4-2.32.5-1.1-2.72.82.22.61.7-1.32.1-1.8-1.31.8
Reaction time mean minus median AUC3.44.47.0-1.9-1.92.6-2.2-1.91.5-2.32.4-1.5-2.62.72.22.52.0-1.51.9-1.9-1.91.7
Reaction time num false alarms0.40.61.6-0.5-0.40.7-0.7-0.51.0-0.91.0-0.3-1.00.81.10.80.8-0.81.2-0.7-0.40.3
Reaction time num false alarms AUC0.10.10.5-0.10.10.3-0.40.10.7-0.40.50.0-0.40.30.60.20.1-0.40.70.00.3-0.2
Reaction time trials correct on left1.11.72.91.51.4-1.61.61.3-1.51.3-1.11.71.3-1.5-1.4-1.4-0.71.1-1.20.60.6-0.7
Reaction time trials on left1.11.52.71.51.3-1.51.51.3-1.51.3-1.11.61.2-1.4-1.3-1.3-0.61.1-1.20.60.5-0.7
Reaction time mean6.18.511.4-3.3-3.43.3-3.2-3.22.7-3.02.8-3.1-2.93.02.92.72.7-2.22.8-2.5-3.12.2
Reaction time mean AUC5.98.010.7-3.2-3.33.3-3.1-3.12.6-2.82.6-3.1-2.92.92.92.72.6-2.22.7-2.4-2.82.1
Median of all reaction times5.67.712.5-3.4-3.53.0-3.1-3.32.7-2.72.3-3.4-2.42.52.72.22.6-2.22.5-2.3-3.21.9
Reaction time omissions2.02.73.8-1.8-1.91.9-1.6-1.81.3-1.61.6-1.7-1.81.81.91.71.6-1.11.5-1.5-1.61.2
Reaction time false alarm rate0.40.61.5-0.7-0.50.9-1.0-0.41.2-0.90.9-0.7-0.90.91.00.80.4-0.61.0-0.2-0.0-0.1
Reaction time premature initiation rate4.45.99.2-2.0-1.92.7-2.3-2.31.9-2.82.9-1.7-2.92.93.02.82.0-1.92.8-2.2-1.22.6
Reaction time premature initiations1.82.54.6-1.1-1.01.6-1.2-1.40.9-1.82.0-0.8-1.91.92.11.81.4-1.32.0-1.7-0.72.1
Std. dev. reaction times4.15.79.1-2.3-2.32.9-2.4-2.31.8-2.62.7-1.9-2.93.02.52.82.2-1.52.4-2.1-2.21.8
Reaction time trials completed1.11.52.71.51.3-1.51.51.3-1.51.3-1.11.61.2-1.4-1.3-1.3-0.61.1-1.20.60.5-0.7
Reaction time trials AUC1.11.62.51.51.3-1.51.51.3-1.51.3-1.11.61.3-1.5-1.4-1.4-0.71.2-1.20.70.5-0.8
Run reversals in cocaine runway, females1.51.52.1-1.4-1.31.4-1.5-1.31.4-1.11.1-1.3-1.21.41.11.01.0-0.90.8-1.0-1.11.2
Run reversals in cocaine runway, males1.51.52.41.11.0-1.31.41.1-1.51.2-1.21.11.5-1.3-1.3-1.3-0.81.2-1.30.91.0-1.3
Latency to leave start box in cocaine runway0.30.42.00.00.1-0.1-0.20.50.50.3-0.1-0.00.4-0.4-1.0-0.4-0.10.9-1.11.00.2-1.4
Latency to leave start box in cocaine runway, F0.80.93.50.50.6-0.50.21.0-0.20.9-0.70.30.8-1.0-1.1-0.8-0.71.5-1.01.40.6-1.9
Latency to leave start box in cocaine runway, M0.20.20.6-0.2-0.20.3-0.3-0.30.8-0.60.7-0.1-0.50.6-0.10.40.8-0.6-0.2-0.40.00.4
Std. dev. time between licks in bursts0.00.00.30.10.1-0.10.00.2-0.2-0.10.00.30.1-0.00.3-0.10.10.30.5-0.1-0.40.2
Total sessions with >9 infusions0.20.21.3-0.2-0.00.5-0.5-0.10.2-0.30.5-0.3-0.60.61.10.6-0.2-0.10.50.20.70.1
Short access day 1 total inactive lever presses0.40.51.8-0.1-0.10.9-0.6-0.20.3-0.81.00.2-1.41.30.70.90.70.20.5-0.5-0.50.2
Short access day 10 total inactive lever presses0.20.21.00.60.70.10.10.7-0.1-0.30.41.0-0.50.40.20.7-0.2-0.00.4-0.10.50.6
Short access day 1 total infusions1.11.23.4-1.4-1.21.3-1.8-1.21.4-1.11.1-1.7-1.01.11.20.70.2-0.80.4-0.10.10.5
Short access day 10 total infusions2.22.54.7-1.6-1.41.8-2.2-1.51.7-1.92.0-1.8-1.81.82.01.60.7-1.11.5-0.7-0.11.1
Short access total infusions2.02.24.6-1.6-1.41.7-2.2-1.41.7-1.71.7-1.8-1.61.72.01.30.7-1.21.3-0.6-0.21.0
Short access day 1 locomotion2.93.15.0-1.8-1.82.0-2.2-1.82.1-1.91.9-1.6-2.02.11.41.71.9-1.11.3-1.4-1.71.0
Short access day 10 total locomotion0.30.30.7-0.6-0.70.6-0.8-0.80.5-0.30.5-0.8-0.20.60.20.20.30.80.3-0.0-0.8-0.8
Short access total locomotion2.22.34.2-1.6-1.61.7-2.1-1.71.7-1.61.7-1.7-1.61.81.41.41.3-0.91.3-1.1-1.10.8
One hour access (0.3 mA shock)3.64.37.9-1.3-1.32.2-2.0-1.31.1-2.42.8-0.7-2.62.62.62.42.1-1.52.7-2.1-1.82.1
Compulsive drug intake2.32.45.0-1.7-1.81.7-1.5-1.62.2-1.41.2-1.5-1.51.31.21.61.9-1.51.1-1.5-1.50.9
One hour access (shock baseline)0.40.51.50.20.20.5-0.40.0-0.5-0.91.20.5-0.91.11.00.70.4-0.21.1-0.6-0.30.9
Social response proportion0.40.53.01.21.0-0.50.90.9-1.00.20.11.7-0.00.2-0.3-0.10.20.40.0-0.4-0.00.3
Social responses0.30.41.00.50.60.4-0.10.4-0.1-0.70.90.9-0.91.00.50.70.20.20.4-0.40.10.9
Social time1.41.94.5-1.7-2.01.3-1.2-1.80.9-1.11.0-1.6-1.11.10.70.82.0-1.00.8-1.5-2.11.0
Soleus weight1.74.87.22.42.7-2.21.52.7-1.22.0-2.12.32.1-2.1-2.0-2.1-2.71.8-2.12.52.5-2.2
Bone: stiffness1.32.13.41.41.3-1.71.51.2-1.71.7-1.81.11.7-1.6-1.1-1.7-1.61.1-1.31.21.3-1.0
Tibialis anterior weight3.813.021.24.54.6-3.73.74.3-3.33.6-3.44.43.1-3.1-3.0-3.2-3.83.4-2.73.23.9-2.9
Time to tail flick, vehicle, before self-admin0.30.30.9-0.6-0.60.6-0.3-0.60.4-0.50.5-0.5-0.70.50.30.80.7-0.20.9-0.5-0.60.2
Time to tail flick, vehicle, after self-admin0.30.31.70.1-0.0-0.10.1-0.4-0.60.3-0.2-0.10.3-0.1-1.0-0.2-0.21.3-1.20.2-0.1-1.0
Time to tail flick, test, before self-admin2.52.45.01.51.5-1.61.21.2-1.51.6-1.51.21.7-1.2-1.4-1.8-1.72.2-1.71.41.5-1.7
Time to tail flick, test, after self-admin0.40.41.10.30.4-0.40.30.3-0.40.6-0.6-0.10.5-0.5-0.3-0.5-1.10.7-0.91.01.0-1.0
Delta time to tail flick, vehicle, before/after SA0.60.62.70.10.1-0.40.1-0.1-0.70.7-0.8-0.30.9-0.7-0.8-0.9-0.81.3-1.70.80.2-0.9
Delta time to tail flick, test, before/after SA0.70.61.3-0.9-0.80.9-0.7-0.80.9-0.80.7-0.9-0.90.40.71.00.5-1.10.7-0.5-0.60.7
Tibia length4.111.617.74.03.8-3.63.83.9-3.73.6-3.54.23.1-3.1-3.7-3.0-2.43.4-3.22.52.1-2.9
Ambulatory time before self-admin0.20.20.7-0.6-0.50.5-0.8-0.40.7-0.50.5-0.6-0.40.30.50.00.30.10.2-0.0-0.10.2
Ambulatory time after self-admin0.10.10.30.20.2-0.30.10.1-0.10.00.10.10.3-0.2-0.5-0.4-0.40.3-0.50.30.50.1
Bone: tissue strength1.00.91.60.80.7-1.01.10.6-1.11.2-1.20.61.0-0.9-1.2-1.0-1.01.2-0.90.80.3-1.3
Total heroin consumption3.84.46.5-2.5-2.32.5-2.5-2.22.4-2.52.4-2.4-2.22.01.62.01.7-1.91.6-1.3-1.81.4
Bone: trabecular number10.616.623.04.24.1-4.34.53.9-4.84.5-4.53.64.2-4.1-3.6-4.1-4.14.2-3.83.63.5-3.3
Bone: trabecular spacing2.32.95.1-2.2-2.31.7-2.2-2.22.2-1.71.6-2.2-1.31.31.01.31.8-1.51.1-1.4-1.80.8
Bone: trabecular thickness8.29.812.73.23.4-3.33.23.5-2.83.3-3.42.93.2-3.1-2.4-3.1-3.62.6-2.83.33.3-2.6
Bone: trabecular tissue density0.10.20.9-0.3-0.30.1-0.5-0.20.30.2-0.3-0.40.4-0.4-0.5-0.4-0.00.7-0.50.4-0.7-0.9
Water consumed over 24 hours0.91.13.71.51.4-1.21.41.2-1.70.9-0.81.90.8-0.8-0.9-0.9-0.40.7-0.70.10.5-0.2
Number of responses in last shaping day0.10.10.40.30.3-0.20.40.3-0.60.1-0.20.40.0-0.0-0.1-0.4-0.10.5-0.30.2-0.2-0.1