Hub : Genes

Pcgf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_008767971.2 0.05 0.05 1.2e-04 0.05 0.03 0.04 0.04 2.3e-05 5.9e-04 4.4e-05 8.3e-05
2 Brain alternative TSS XM_008767971.2 0.04 0.04 2.8e-03 0.03 0.02 0.03 0.03 7.4e-04 6.3e-03 1.6e-03 1.2e-03
3 OFC isoform ratio NM_001105836.2 0.33 0.2 3.5e-04 0.1 0.05 0.06 0.04 1.9e-03 2.1e-02 1.3e-02 3.6e-02
4 Liver alternative polyA NM_001105836.2 0.06 0.04 1.7e-08 0.07 0.07 0.07 0.07 1.2e-08 3.5e-08 2.0e-08 2.8e-08
5 Liver alternative polyA XM_039085606.1 0.06 0.04 1.8e-08 0.07 0.07 0.07 0.07 1.6e-08 5.1e-08 4.1e-08 6.3e-08
6 Liver isoform ratio XM_008767973.3 0.02 0.01 5.6e-03 0.01 0.01 0.01 0.01 2.0e-02 1.5e-02 3.6e-02 4.2e-02
7 Adipose gene expression Pcgf2 0.03 0.03 2.7e-04 0.03 0.03 0.03 0.03 2.5e-04 2.1e-04 5.1e-04 3.4e-04
8 PL alternative polyA NM_001105836.2 0.02 0.02 4.1e-03 0.01 0.02 0.01 0.01 1.5e-02 5.2e-03 3.0e-02 1.7e-02
9 PL alternative polyA XM_039085606.1 0.02 0.02 5.3e-03 0.01 0.02 0.01 0.01 1.3e-02 5.7e-03 3.3e-02 1.9e-02
10 Brain alternative polyA NM_001105836.2 0.04 0.03 2.4e-05 0.03 0.05 0.04 0.04 4.3e-04 4.1e-05 1.3e-04 1.9e-04
11 Brain alternative polyA XM_039085606.1 0.04 0.03 2.3e-05 0.03 0.05 0.04 0.04 4.1e-04 3.8e-05 1.2e-04 2.0e-04
12 PL mRNA stability Pcgf2 0.03 0.02 1.8e-04 0.03 0.03 0.02 0.03 3.7e-04 1.2e-04 2.5e-03 5.1e-04
13 PL isoform ratio NM_001105836.2 0.02 0.02 4.9e-03 0.01 0.01 0.02 0.01 8.3e-03 7.5e-03 5.7e-03 7.7e-03
14 Liver isoform ratio NM_001105836.2 0.04 0.03 3.0e-07 0.06 0.06 0.06 0.06 2.6e-07 1.0e-06 7.2e-07 8.7e-07
15 Brain isoform ratio NM_001105836.2 0.05 0.04 7.2e-05 0.05 0.04 0.05 0.05 2.7e-05 7.2e-05 2.8e-05 2.9e-05
16 BLA gene expression Pcgf2 0.07 0.06 2.6e-03 0.03 0.03 0.03 0.03 6.8e-03 7.7e-03 5.9e-03 1.0e-02
17 Brain gene expression Pcgf2 0.06 0.04 4.5e-06 0.05 0.05 0.06 0.06 1.1e-05 1.0e-05 6.5e-06 6.6e-06
18 OFC alternative polyA NM_001105836.2 0.43 0.22 4.8e-05 0.14 0.04 0.09 0.13 2.9e-04 3.6e-02 4.7e-03 5.8e-04
19 OFC alternative polyA XM_039085606.1 0.45 0.22 6.2e-05 0.14 0.04 0.08 0.13 3.1e-04 3.8e-02 5.0e-03 5.9e-04
20 LHb isoform ratio NM_001105836.2 0.25 0.18 9.0e-04 0.14 0.06 0.15 0.07 3.1e-04 1.3e-02 2.2e-04 7.8e-03
21 LHb mRNA stability Pcgf2 0.13 0.1 1.0e-02 0.01 0 0.04 -0.01 1.4e-01 2.8e-01 4.0e-02 4.9e-01
22 PL gene expression Pcgf2 0.06 0.04 1.1e-06 0.06 0.06 0.06 0.06 3.2e-07 7.2e-07 7.3e-07 1.2e-06
23 NAcc isoform ratio NM_001105836.2 0.03 0.02 7.4e-03 0.01 0.01 0.02 0.01 8.9e-03 1.2e-02 4.3e-03 9.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.93.24.2-2.1-2.12.02.1-2.11.81.9-1.81.8-1.91.91.81.61.61.7-1.6-1.81.5-1.51.5-1.6-1.81.5
Area under the delay curve0.80.81.3-0.9-0.90.80.8-0.81.00.8-0.90.9-0.90.80.71.01.01.1-0.9-1.01.0-1.01.0-0.7-1.00.0
BMI with tail1.23.85.82.42.4-2.4-2.42.4-2.4-1.82.1-2.01.9-1.8-1.4-2.1-2.0-2.12.11.4-1.91.9-1.91.31.10.2
BMI without tail0.10.20.30.30.3-0.3-0.40.4-0.5-0.40.5-0.50.5-0.5-0.4-0.4-0.5-0.60.50.4-0.30.3-0.40.40.4-0.3
Body weight5.623.527.35.25.2-5.2-5.25.2-5.0-5.15.0-5.05.0-5.0-4.9-4.8-4.8-4.74.84.4-4.54.5-4.54.54.3-4.4
Weight adjusted by age0.20.20.50.30.3-0.3-0.30.3-0.4-0.40.4-0.40.4-0.4-0.5-0.5-0.5-0.50.60.6-0.60.6-0.50.50.7-0.6
Bone surface0.00.10.20.00.0-0.1-0.00.0-0.2-0.10.2-0.20.2-0.2-0.2-0.3-0.3-0.30.30.1-0.40.4-0.30.30.1-0.5
Bone volume0.00.10.2-0.4-0.40.40.4-0.40.30.3-0.30.3-0.30.30.30.00.00.1-0.1-0.3-0.10.10.0-0.1-0.30.1
Breakpoint value in progressive ratio session1.21.31.91.21.2-1.4-1.31.3-1.1-1.31.1-1.11.2-1.2-1.3-1.2-0.9-0.81.01.0-1.21.2-1.01.11.0-1.3
Number of licking bursts0.50.60.9-0.9-0.90.90.9-0.90.80.8-0.80.8-0.80.80.80.80.70.7-0.7-0.70.7-0.70.7-0.6-0.60.6
Context. condit. distance diff. score0.40.50.80.70.7-0.6-0.70.7-0.7-0.60.7-0.70.6-0.6-0.6-0.8-0.6-0.60.70.8-0.90.9-0.90.80.8-0.6
Locomotion velocity, session 10.80.91.20.90.9-1.0-0.90.9-1.0-0.91.0-1.01.0-0.9-0.9-1.0-1.1-1.11.00.8-0.90.9-0.90.80.8-0.5
Locomotion distance, session 14.05.15.92.42.4-2.3-2.42.4-2.3-2.42.3-2.42.4-2.4-2.4-2.1-2.3-2.32.22.1-2.02.0-2.02.02.0-2.3
Locomotion velocity, session 20.91.12.10.90.9-0.9-0.90.9-0.9-1.11.0-1.01.0-1.1-1.2-1.0-1.0-1.01.01.1-1.01.0-1.01.21.1-1.5
Locomotion distance, session 21.31.83.41.21.2-1.2-1.31.3-1.2-1.41.4-1.41.4-1.4-1.6-1.2-1.4-1.41.31.3-1.21.2-1.11.41.3-1.8
Locomotion velocity, session 30.10.20.30.50.5-0.5-0.50.5-0.4-0.50.4-0.40.4-0.5-0.5-0.3-0.4-0.30.30.2-0.30.3-0.20.20.2-0.4
Locomotion distance, session 30.80.92.30.80.8-0.8-0.70.7-0.8-1.00.9-0.91.0-1.0-1.1-0.9-0.9-0.90.90.9-0.90.9-0.91.11.0-1.5
Stereotopy head waving bouts, day 34.04.76.2-2.1-2.12.12.0-2.02.12.2-2.22.2-2.22.22.32.22.22.2-2.2-2.12.1-2.12.1-2.2-2.12.5
Stereotopy head waving duration, day 30.80.92.0-0.7-0.70.70.7-0.70.90.9-0.90.9-1.01.01.01.01.00.9-1.0-1.01.0-1.01.0-1.1-1.01.4
Locomotion velocity, session 70.60.71.11.01.0-1.0-1.01.0-0.8-1.00.9-0.90.9-0.9-1.0-0.7-0.7-0.70.70.6-0.60.6-0.50.60.6-1.0
Locomotion distance, session 70.20.21.70.50.5-0.5-0.50.5-0.2-0.50.4-0.40.4-0.5-0.6-0.2-0.1-0.20.20.4-0.20.2-0.20.50.5-1.3
Stereotopy head waving bouts, day 70.91.01.6-1.2-1.21.11.2-1.21.01.2-1.11.1-1.11.11.10.80.90.9-0.9-0.90.7-0.70.8-0.9-0.81.3
Stereotopy head waving duration, day 70.20.30.7-0.7-0.70.60.6-0.60.50.6-0.50.5-0.50.60.60.30.30.4-0.3-0.30.2-0.20.3-0.5-0.30.8
Locomotion velocity, session 86.78.08.83.03.0-2.9-3.03.0-2.9-2.82.9-2.92.8-2.8-2.7-2.9-2.8-2.82.82.7-2.92.9-2.82.72.7-2.3
Locomotion distance, session 81.92.83.31.61.6-1.4-1.61.6-1.6-1.71.7-1.71.7-1.7-1.7-1.7-1.7-1.61.71.7-1.71.7-1.71.71.7-1.8
Degree of sensitization distance0.20.20.40.60.6-0.6-0.60.6-0.4-0.50.4-0.40.4-0.4-0.4-0.3-0.3-0.30.30.4-0.20.2-0.30.30.3-0.4
Degree of sensitization stereotypy1.51.72.2-1.5-1.51.41.5-1.51.41.4-1.41.4-1.41.41.41.11.21.2-1.2-1.11.0-1.01.1-1.1-1.11.3
Conditioned locomotion0.10.10.2-0.2-0.20.30.2-0.20.40.4-0.40.4-0.40.40.40.40.40.4-0.4-0.50.4-0.40.4-0.4-0.40.4
Cocaine response after cond. corrected2.22.43.0-1.7-1.71.71.7-1.71.61.7-1.61.6-1.61.61.61.51.31.3-1.3-1.51.4-1.41.4-1.5-1.51.6
Cocaine response after cond. not corrected3.53.84.7-2.2-2.22.22.2-2.22.12.1-2.02.0-2.02.01.91.91.81.8-1.8-1.91.8-1.81.8-1.8-1.81.6
Cocaine response before conditioning0.91.11.8-1.1-1.11.11.1-1.11.21.0-1.11.1-1.11.00.91.11.31.3-1.3-0.81.1-1.11.0-0.7-0.70.2
Saline control response0.50.61.1-0.6-0.60.60.6-0.60.70.7-0.70.7-0.70.70.70.90.80.8-0.8-1.01.0-1.01.0-1.0-1.00.9
Bone: connectivity density2.54.04.9-2.2-2.22.12.2-2.22.12.1-2.12.1-2.12.12.01.81.92.0-2.0-2.01.7-1.71.8-1.8-2.01.6
Bone: cortical apparent density4.66.07.8-2.8-2.82.82.8-2.82.82.6-2.62.6-2.62.62.42.32.42.5-2.4-2.22.1-2.12.2-2.0-2.01.5
Bone: cortical area0.20.20.5-0.7-0.70.70.7-0.70.50.5-0.50.5-0.50.50.40.50.30.4-0.4-0.30.5-0.50.4-0.2-0.30.0
Bone: cortical porosity0.91.01.4-0.8-0.81.00.8-0.80.90.9-0.90.9-0.90.91.01.10.90.9-1.0-1.01.2-1.21.1-1.1-1.01.1
Bone: cortical porosity1.21.42.1-1.0-1.01.11.0-1.01.11.0-1.11.1-1.11.11.11.41.11.1-1.2-1.21.4-1.41.4-1.3-1.21.2
Bone: cortical thickness1.32.23.7-1.9-1.91.91.9-1.91.61.6-1.51.5-1.51.51.31.41.21.3-1.3-1.11.4-1.41.2-1.0-1.00.5
Bone: cortical thickness4.85.66.9-2.6-2.62.62.6-2.62.62.3-2.42.4-2.42.32.12.52.42.4-2.4-2.22.4-2.42.4-2.0-2.01.1
Bone: cortical tissue density4.66.07.7-2.8-2.82.82.8-2.82.82.6-2.62.6-2.62.62.42.32.42.6-2.5-2.22.1-2.12.2-2.0-2.01.5
Condit. Reinf. active minus inactive responses0.40.40.5-0.7-0.70.60.7-0.70.70.6-0.70.7-0.70.70.60.70.70.7-0.7-0.60.7-0.70.6-0.5-0.60.4
Condit. Reinf. active-inactive response ratio0.80.91.2-0.8-0.80.70.8-0.80.90.9-0.90.9-0.90.91.01.01.11.1-1.1-1.01.0-1.01.0-0.9-1.00.9
Condit. Reinf. active responses0.60.81.0-1.0-1.00.91.0-1.00.90.9-0.90.9-0.90.90.90.90.80.8-0.8-0.80.9-0.90.8-0.7-0.80.6
Condit. Reinf. inactive responses0.50.60.8-0.9-0.90.90.9-0.90.80.8-0.80.8-0.80.80.70.80.60.7-0.7-0.70.8-0.80.8-0.8-0.70.6
Incentive salience index mean1.31.51.8-1.3-1.31.21.3-1.31.31.2-1.31.2-1.21.21.21.31.21.3-1.3-1.21.3-1.31.2-1.1-1.20.9
Condit. Reinf. lever presses1.01.41.7-1.2-1.21.21.2-1.21.21.1-1.21.1-1.11.11.11.31.11.1-1.2-1.11.3-1.31.2-1.1-1.10.9
Condit. Reinf. active minus inactive responses0.70.91.5-0.8-0.80.80.8-0.80.80.8-0.80.8-0.80.80.91.00.90.8-0.8-1.21.0-1.01.1-1.2-1.21.0
Condit. Reinf. active-inactive response ratio0.30.41.0-0.5-0.50.50.5-0.50.40.5-0.50.5-0.50.50.60.60.40.3-0.4-0.80.7-0.70.7-0.8-0.81.0
Condit. Reinf. active responses1.11.62.4-1.1-1.11.11.1-1.11.21.2-1.21.2-1.21.21.21.31.41.2-1.2-1.51.3-1.31.4-1.4-1.51.2
Condit. Reinf. inactive responses2.43.03.7-1.6-1.61.61.6-1.61.81.6-1.71.7-1.71.71.71.71.91.9-1.9-1.91.7-1.71.8-1.8-1.81.4
Condit. Reinf. lever presses0.00.10.2-0.2-0.20.20.2-0.20.20.1-0.20.2-0.20.10.10.30.30.2-0.2-0.40.2-0.20.4-0.4-0.40.0
Condit. Reinf. lever reinforcers received1.01.52.2-1.1-1.11.01.1-1.11.21.1-1.21.2-1.21.21.11.21.31.2-1.2-1.51.2-1.21.4-1.4-1.51.1
Conditioned reinforcement - actives2.02.02.9-1.0-1.01.00.9-0.91.31.3-1.31.3-1.41.41.51.51.61.5-1.5-1.61.6-1.61.6-1.7-1.71.7
Conditioned reinforcement - inactives1.71.93.4-1.0-1.01.00.9-0.91.21.1-1.31.3-1.21.21.31.71.51.4-1.4-1.71.8-1.81.8-1.7-1.71.3
Conditioned locomotion1.82.13.7-1.3-1.31.21.1-1.11.31.4-1.41.4-1.41.41.51.51.51.4-1.3-1.71.6-1.61.6-1.8-1.81.9
Patch foraging indifference point 0 sec1.52.33.1-1.5-1.51.51.5-1.51.51.5-1.51.5-1.51.51.51.51.41.5-1.5-1.81.6-1.61.6-1.7-1.71.5
Patch foraging indifference point AUC0.20.20.70.10.1-0.1-0.10.1-0.3-0.20.3-0.30.3-0.3-0.3-0.6-0.6-0.50.50.7-0.70.7-0.80.80.7-0.6
Delay disc. indifference point, 0s delay1.21.31.7-1.3-1.31.31.3-1.31.21.1-1.21.2-1.11.11.01.21.01.3-1.1-1.11.2-1.21.2-1.1-1.10.7
Delay disc. indifference point, 16s delay0.60.60.8-0.9-0.90.80.8-0.80.90.8-0.80.8-0.80.80.70.70.80.9-0.8-0.90.6-0.60.6-0.5-0.9-0.0
Delay disc. indifference point, 2s delay2.32.63.2-1.7-1.71.61.6-1.61.71.5-1.61.6-1.51.51.41.81.61.7-1.6-1.71.8-1.81.8-1.5-1.70.8
Delay disc. indifference point, 24s delay0.10.10.7-0.3-0.30.20.2-0.20.30.2-0.20.2-0.20.20.0-0.10.10.3-0.20.0-0.20.2-0.30.50.1-0.9
Delay disc. indifference point, 4s delay0.50.50.9-1.0-1.00.90.9-0.90.80.5-0.60.6-0.50.50.20.80.70.7-0.6-0.50.8-0.80.7-0.2-0.5-0.8
Delay disc. indifference point, 8s delay0.80.81.3-0.7-0.70.60.6-0.60.90.7-0.90.9-0.80.80.81.11.11.2-0.9-1.11.1-1.11.1-0.9-1.10.4
Indifference point function ln k0.00.00.1-0.1-0.10.10.2-0.20.10.1-0.10.1-0.10.10.10.20.30.1-0.2-0.30.3-0.30.3-0.3-0.20.1
Indifference point function log k0.00.00.1-0.1-0.10.10.2-0.20.10.1-0.10.1-0.10.10.10.20.30.1-0.2-0.30.3-0.30.3-0.3-0.20.1
Patch foraging total patch changes 0 sec0.91.52.0-1.2-1.21.21.2-1.21.21.2-1.21.2-1.21.21.11.21.11.2-1.1-1.41.2-1.21.3-1.4-1.41.1
Patch foraging total patch changes 12 sec4.45.76.2-2.4-2.42.52.4-2.42.42.4-2.42.4-2.42.42.32.42.22.3-2.3-2.52.4-2.42.4-2.4-2.52.1
Patch foraging total patch changes 18 sec0.40.51.0-0.9-0.90.90.9-0.90.60.9-0.70.7-0.70.80.80.40.40.5-0.4-0.70.4-0.40.4-0.7-0.81.0
Patch foraging total patch changes 24 sec1.82.23.6-1.9-1.91.91.9-1.91.51.7-1.51.5-1.51.51.51.31.11.3-1.2-1.31.2-1.21.1-1.2-1.31.3
Patch foraging total patch changes 6 sec1.21.82.5-1.6-1.61.61.6-1.61.31.5-1.41.4-1.41.41.41.21.01.2-1.2-1.41.1-1.11.2-1.3-1.51.3
Patch foraging time to switch 0 sec0.10.10.4-0.2-0.20.30.2-0.20.30.3-0.30.3-0.30.30.40.40.30.3-0.3-0.50.4-0.40.5-0.6-0.60.6
Patch foraging water rate 0 sec0.10.10.50.10.1-0.1-0.20.2-0.2-0.20.2-0.20.2-0.2-0.2-0.4-0.2-0.10.20.4-0.50.5-0.60.60.5-0.7
Patch foraging water rate 12 sec0.40.61.40.50.5-0.6-0.50.5-0.7-0.70.7-0.70.7-0.8-0.8-0.6-0.8-0.70.71.0-0.60.6-0.81.01.1-1.2
Patch foraging water rate 18 sec0.50.61.2-0.8-0.80.70.8-0.80.90.7-0.80.8-0.70.70.60.81.01.1-0.9-0.60.9-0.90.8-0.5-0.5-0.1
Patch foraging water rate 24 sec0.30.50.9-0.5-0.50.50.5-0.50.70.6-0.70.7-0.70.70.70.70.80.9-0.8-0.70.8-0.80.6-0.6-0.70.5
Patch foraging water rate 6 sec0.60.91.5-1.1-1.11.11.1-1.11.11.1-1.11.1-1.11.11.00.91.11.2-1.1-0.60.8-0.80.7-0.6-0.50.6
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.0-0.00.10.1-0.1-0.00.1-0.00.0-0.00.00.1-0.2-0.1-0.00.00.2-0.30.3-0.20.10.10.4
Distance traveled before self-admin0.10.10.30.50.5-0.5-0.50.5-0.3-0.50.3-0.30.4-0.4-0.4-0.0-0.1-0.10.1-0.00.1-0.10.2-0.0-0.0-0.2
Distance traveled after self-admin1.61.72.81.71.7-1.6-1.61.6-1.4-1.41.3-1.31.3-1.3-1.2-1.3-1.1-1.11.11.2-1.31.3-1.21.11.2-0.7
Extensor digitorum longus weight7.931.133.75.75.7-5.6-5.75.7-5.8-5.65.7-5.75.7-5.7-5.5-5.7-5.7-5.75.75.3-5.55.5-5.55.45.2-4.8
Bone: elastic displacement0.00.00.1-0.2-0.20.30.2-0.20.10.1-0.10.1-0.10.10.10.20.10.0-0.1-0.30.3-0.30.3-0.3-0.30.3
Bone: elastic work0.00.00.1-0.1-0.10.00.1-0.1-0.0-0.10.1-0.10.1-0.1-0.20.1-0.2-0.10.10.10.1-0.10.00.10.1-0.4
Bone: endosteal estimation1.94.25.42.32.3-2.3-2.32.3-2.1-2.22.1-2.12.1-2.1-2.0-2.0-1.9-1.91.91.9-1.91.9-1.91.91.8-1.8
Bone: endosteal perimeter1.73.54.52.12.1-2.1-2.12.1-2.0-2.02.0-1.91.9-1.9-1.8-1.8-1.8-1.81.81.6-1.81.8-1.71.61.5-1.4
Epididymis fat weight0.30.71.31.11.1-1.1-1.11.1-0.7-0.90.8-0.80.8-0.8-0.8-0.9-0.5-0.40.60.7-0.70.7-0.80.80.7-1.0
Delta time in closed arm before/after self-admin3.53.44.11.91.9-1.9-1.91.9-1.9-1.91.9-1.91.9-1.9-1.8-2.0-1.8-1.81.81.7-2.02.0-1.91.71.8-1.7
Delta time in open arm before/after self-admin0.10.10.2-0.4-0.40.20.2-0.20.20.2-0.20.2-0.20.20.20.40.10.2-0.2-0.20.4-0.40.4-0.3-0.30.4
Diff in mean of infusions in LGA sessions0.20.20.80.80.8-0.8-0.90.9-0.4-0.50.3-0.30.3-0.3-0.2-0.3-0.00.10.00.2-0.10.1-0.10.10.1-0.1
Delay discount exponential model param0.40.40.70.60.6-0.6-0.60.6-0.8-0.50.6-0.60.6-0.6-0.4-0.7-0.7-0.80.60.7-0.70.7-0.70.40.70.3
Extinction: sum of active levers before priming0.90.91.60.90.9-1.1-1.01.0-0.8-0.90.8-0.80.9-0.9-0.9-1.0-0.7-0.60.61.2-1.01.0-1.11.21.3-1.1
Active lever presses in extinction session 60.20.20.3-0.5-0.50.50.5-0.50.50.5-0.50.5-0.50.50.50.20.50.6-0.50.10.0-0.00.1-0.10.20.3
Bone: final force1.21.92.2-1.4-1.41.41.4-1.41.51.4-1.41.4-1.41.41.31.51.31.4-1.4-1.31.4-1.41.3-1.2-1.21.0
Bone: final moment1.01.61.9-1.3-1.31.31.3-1.31.31.3-1.31.3-1.31.31.21.41.21.3-1.3-1.21.4-1.41.3-1.1-1.20.9
Food consumed during 24 hour testing period1.11.31.80.90.9-0.9-0.90.9-1.1-1.11.2-1.21.2-1.2-1.2-1.1-1.3-1.31.31.2-1.11.1-1.11.21.2-1.2
Glucose0.50.81.1-1.0-1.01.01.0-1.01.00.9-0.90.9-0.90.90.80.90.90.9-0.9-0.71.0-1.00.9-0.7-0.60.4
Heart weight2.83.95.52.32.3-2.3-2.32.3-2.1-2.02.0-2.02.0-2.0-1.8-1.9-1.9-1.71.81.9-1.81.8-1.91.81.8-1.3
Delay discount hyperbolic model param0.60.61.00.80.8-0.7-0.70.7-0.9-0.70.8-0.80.7-0.7-0.5-0.9-0.9-1.00.80.9-1.01.0-0.90.60.90.2
Intermittent access intake day 1-15 change0.20.20.3-0.2-0.20.20.3-0.30.40.4-0.40.4-0.40.50.50.30.60.5-0.6-0.30.5-0.50.2-0.3-0.30.4
Intermittent access intake escalation0.10.10.3-0.1-0.10.10.2-0.20.20.3-0.30.3-0.30.30.40.30.40.3-0.4-0.30.4-0.40.3-0.4-0.30.6
Intermittent access intake escalation 20.10.10.30.30.3-0.3-0.10.1-0.4-0.20.3-0.30.3-0.3-0.2-0.5-0.3-0.40.30.5-0.50.5-0.60.40.5-0.1
Intermitt. access day 1 inactive lever presses1.01.11.9-0.6-0.60.60.6-0.61.00.8-0.91.0-0.90.91.01.31.21.2-1.1-1.21.4-1.41.3-1.2-1.31.0
Intermitt. access day 15 inactive lever presses3.13.44.3-2.1-2.12.02.0-2.01.71.9-1.81.8-1.81.81.91.81.71.6-1.5-1.91.8-1.81.8-1.9-2.02.0
Intermitt. access escalation Index0.70.61.00.70.7-0.7-0.80.8-0.8-0.70.8-0.80.8-0.8-0.7-0.8-1.0-0.90.80.6-0.80.8-0.70.60.6-0.5
Intermittent access day 1 total infusions0.10.10.3-0.2-0.20.30.2-0.20.40.3-0.40.4-0.40.40.40.40.50.5-0.4-0.30.5-0.50.3-0.3-0.30.3
Intermittent access day 15 total infusions0.30.30.6-0.3-0.30.40.3-0.30.50.5-0.50.6-0.60.60.60.60.80.7-0.7-0.50.8-0.80.5-0.5-0.50.6
Intermittent access terminal intake (last 3 days)0.30.30.6-0.4-0.40.40.5-0.50.60.6-0.60.6-0.60.60.70.40.70.7-0.7-0.60.6-0.60.4-0.5-0.50.6
Intermittent access total infusions0.00.10.20.10.1-0.0-0.10.10.20.1-0.20.2-0.20.20.20.20.50.3-0.3-0.20.4-0.40.2-0.2-0.20.2
Intermittent access day 1 locomotion0.40.40.6-0.5-0.50.60.4-0.40.60.5-0.60.6-0.60.60.60.80.80.7-0.7-0.60.8-0.80.7-0.6-0.60.5
Intermittent access day 15 total locomotion0.60.61.1-0.8-0.80.80.7-0.70.80.8-0.80.8-0.80.80.90.81.00.9-0.9-0.50.9-0.90.6-0.6-0.40.7
Intermittent access total locomotion0.80.91.3-0.8-0.80.90.7-0.70.90.9-0.91.0-0.90.91.01.11.11.0-0.9-0.91.1-1.11.0-1.0-0.91.0
Intermittent access standard deviation0.20.20.4-0.3-0.30.30.5-0.50.40.5-0.50.5-0.50.50.50.30.60.5-0.5-0.30.4-0.40.4-0.4-0.30.6
Left kidney weight2.88.011.92.62.6-2.6-2.52.5-2.6-2.82.7-2.82.8-2.8-3.0-2.9-2.8-2.62.83.0-2.92.9-2.93.13.0-3.4
Right kidney weight0.71.93.51.21.2-1.2-1.11.1-1.2-1.31.3-1.31.3-1.3-1.4-1.4-1.4-1.31.31.6-1.41.4-1.51.71.7-1.9
Cocaine induced anxiety2.22.53.01.61.6-1.6-1.51.5-1.6-1.51.6-1.61.6-1.5-1.5-1.7-1.6-1.61.61.6-1.71.7-1.71.61.5-1.3
Post-drug Anxiety0.00.00.00.20.2-0.2-0.20.2-0.2-0.10.1-0.10.1-0.1-0.1-0.2-0.2-0.10.10.0-0.10.1-0.10.0-0.00.2
Baseline Anxiety3.73.95.3-1.9-1.91.91.8-1.81.81.9-1.91.9-1.91.92.02.01.81.9-1.9-2.22.1-2.12.2-2.3-2.22.2
Tail length1.64.818.91.61.6-1.6-1.61.6-1.7-2.32.0-2.12.3-2.3-2.8-1.7-1.9-1.91.92.5-1.71.7-1.82.72.6-4.4
Length with tail5.620.538.94.24.2-4.2-4.24.2-4.1-4.74.5-4.54.7-4.7-5.1-4.3-4.3-4.24.34.7-4.24.2-4.24.94.8-6.2
Length without tail4.710.312.13.53.5-3.4-3.43.4-3.2-3.33.2-3.23.2-3.2-3.2-3.2-3.0-3.03.13.0-3.13.1-3.13.13.0-3.1
Times rat made contact with spout0.81.01.5-1.2-1.21.21.2-1.21.01.0-1.01.0-1.01.00.91.00.80.7-0.8-0.90.9-0.90.9-0.8-0.80.7
Lifetime Intake0.00.00.10.10.1-0.1-0.10.10.10.1-0.10.1-0.10.10.20.10.40.3-0.2-0.10.3-0.30.1-0.1-0.10.1
Liver weight, left0.10.21.30.40.4-0.3-0.40.4-0.3-0.40.4-0.40.4-0.4-0.5-0.4-0.3-0.30.30.5-0.40.4-0.50.80.5-1.1
Liver weight, right0.10.11.6-0.1-0.10.10.1-0.10.2-0.1-0.10.00.0-0.1-0.30.00.20.2-0.20.2-0.00.0-0.10.50.4-1.3
Locomotor activity0.71.11.9-1.1-1.11.11.1-1.11.01.1-1.01.1-1.11.11.20.80.90.9-0.9-1.10.7-0.70.9-1.1-1.11.4
Locomotor testing distance3.55.88.6-2.2-2.22.22.2-2.22.32.5-2.42.5-2.52.52.62.22.42.5-2.5-2.52.2-2.22.3-2.6-2.62.9
Locomotor testing rearing5.28.09.3-2.9-2.93.03.0-3.02.93.0-3.03.0-3.03.03.02.62.93.0-3.0-2.62.5-2.52.5-2.6-2.42.7
Locomotion in novel chamber3.84.79.3-3.1-3.12.93.0-3.02.32.3-2.22.2-2.12.11.92.01.81.8-1.9-1.61.8-1.81.4-1.2-1.40.7
Locomotion in novel chamber post-restriction0.70.91.7-1.0-1.00.91.0-1.00.81.0-0.90.9-1.01.01.10.70.60.7-0.8-1.00.7-0.70.8-1.1-1.01.3
Fecal boli incidents, locomotor time 10.20.30.50.40.4-0.4-0.40.4-0.6-0.40.5-0.50.4-0.4-0.3-0.5-0.7-0.60.60.7-0.60.6-0.60.40.70.3
Change in fecal boli incidents, locomotor task0.10.10.5-0.3-0.30.20.2-0.20.50.3-0.40.4-0.30.30.20.30.50.7-0.5-0.10.3-0.30.20.0-0.0-0.5
Time >=10cm from walls, locomotor time 11.01.01.9-0.8-0.80.90.9-0.90.90.9-0.90.9-0.90.90.91.21.00.9-0.9-0.71.3-1.31.1-1.1-0.71.4
Bouts of movement, locomotor time 10.30.40.90.90.9-0.8-0.80.8-0.6-0.70.6-0.60.6-0.6-0.6-0.6-0.4-0.30.60.3-0.50.5-0.40.40.2-0.6
Total resting periods, locomotor time 10.50.61.21.11.1-1.0-1.01.0-0.8-0.90.8-0.80.8-0.8-0.8-0.7-0.6-0.50.80.5-0.70.7-0.50.50.3-0.8
Rest time, locomotor task time 10.00.00.20.10.1-0.00.0-0.00.0-0.0-0.00.0-0.00.0-0.00.3-0.10.1-0.1-0.20.3-0.30.5-0.4-0.30.1
Distance moved, locomotor task time 10.20.20.5-0.5-0.50.40.4-0.40.50.4-0.50.5-0.40.40.30.40.70.4-0.6-0.40.3-0.30.3-0.2-0.40.1
Vertical activity count, locomotor time 10.00.00.10.10.1-0.1-0.20.2-0.1-0.10.1-0.10.1-0.1-0.1-0.10.2-0.1-0.10.3-0.10.1-0.30.40.3-0.1
Time >=10cm from walls, locomotor time 22.02.12.6-1.6-1.61.61.6-1.61.51.4-1.51.5-1.41.41.31.61.51.5-1.3-1.11.6-1.61.5-1.4-1.11.2
Bouts of movement, locomotor time 20.10.10.3-0.2-0.20.20.3-0.30.30.3-0.40.4-0.40.40.40.30.60.5-0.2-0.50.3-0.30.5-0.5-0.60.5
Total resting periods, locomotor time 20.10.10.30.10.1-0.00.0-0.00.10.1-0.10.2-0.20.20.20.20.40.30.0-0.30.3-0.30.4-0.5-0.50.5
Rest time, locomotor task time 20.91.01.41.21.2-1.2-1.21.2-1.1-1.11.1-1.11.1-1.0-1.0-1.0-1.0-0.91.21.0-0.90.9-0.80.70.9-0.6
Distance moved, locomotor task time 20.00.00.5-0.1-0.10.20.2-0.20.1-0.10.0-0.10.1-0.1-0.2-0.10.0-0.1-0.10.0-0.10.1-0.10.30.1-0.7
Vertical activity count, locomotor time 20.00.00.40.10.1-0.1-0.20.2-0.0-0.20.1-0.10.2-0.2-0.20.00.1-0.1-0.2-0.00.1-0.1-0.00.30.0-0.6
Light reinforcement 12.34.15.8-1.8-1.81.81.7-1.71.92.0-2.02.0-2.02.02.12.12.02.0-2.0-2.22.1-2.12.2-2.3-2.22.4
Light reinforcement 20.60.81.0-0.9-0.90.90.8-0.80.90.9-0.90.9-0.90.90.91.00.91.0-0.9-1.00.9-0.91.0-1.0-1.00.9
Bone: marrow area1.84.05.12.22.2-2.3-2.22.2-2.1-2.12.0-2.02.0-2.0-2.0-1.9-1.9-1.81.81.8-1.91.9-1.91.91.8-1.8
Bone: maximum diameter0.00.00.0-0.2-0.20.20.2-0.20.10.1-0.10.1-0.10.10.10.1-0.00.1-0.1-0.10.1-0.10.0-0.0-0.10.0
Bone: maximum force0.00.10.1-0.3-0.30.20.3-0.30.30.3-0.30.3-0.30.30.20.40.20.3-0.3-0.10.4-0.40.2-0.0-0.0-0.0
Bone: maximum moment0.00.00.1-0.2-0.20.10.2-0.20.20.1-0.20.1-0.10.10.10.30.10.2-0.2-0.00.3-0.30.20.0-0.0-0.2
Mean time between licks in bursts1.21.62.11.41.4-1.4-1.41.4-1.4-1.31.4-1.41.3-1.3-1.2-1.2-1.3-1.41.31.1-1.11.1-1.11.01.0-0.8
Mean num. licks in bursts0.00.00.0-0.0-0.00.00.0-0.00.00.0-0.00.0-0.00.00.00.10.10.0-0.1-0.10.2-0.20.2-0.1-0.10.1
Cd content in liver0.10.10.3-0.2-0.20.20.2-0.20.40.3-0.30.3-0.30.30.30.40.50.5-0.5-0.30.4-0.40.4-0.3-0.30.2
Co content in liver1.41.61.81.31.3-1.3-1.31.3-1.3-1.31.3-1.31.3-1.3-1.2-1.3-1.3-1.31.31.3-1.31.3-1.31.21.3-1.0
Cu content in liver1.01.21.41.21.2-1.2-1.21.2-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.11.11.0-1.11.1-1.01.01.0-1.1
Fe content in liver1.62.03.11.31.3-1.3-1.31.3-1.3-1.41.4-1.41.5-1.5-1.5-1.4-1.4-1.41.41.4-1.41.4-1.31.51.4-1.7
K content in liver0.20.20.4-0.7-0.70.60.7-0.70.50.5-0.50.4-0.50.50.40.30.30.3-0.3-0.20.3-0.30.3-0.3-0.30.3
Mg content in liver0.20.20.5-0.7-0.70.70.7-0.70.50.5-0.50.5-0.50.50.40.40.30.3-0.3-0.40.3-0.30.4-0.4-0.40.2
Mn content in liver0.40.40.7-0.8-0.80.80.8-0.80.70.7-0.70.7-0.70.70.60.60.60.6-0.6-0.50.5-0.50.5-0.5-0.50.5
Na content in liver0.30.30.8-0.5-0.50.50.5-0.50.40.6-0.50.5-0.50.50.60.40.30.3-0.3-0.60.3-0.30.5-0.7-0.60.9
Rb content in liver1.31.62.6-1.1-1.11.11.1-1.11.21.2-1.21.2-1.21.21.31.21.21.2-1.2-1.51.3-1.31.4-1.4-1.61.3
Se content in liver1.92.43.2-1.8-1.81.61.8-1.81.71.7-1.61.6-1.61.61.51.51.51.5-1.5-1.31.3-1.31.4-1.3-1.21.2
Sr content in liver0.30.30.90.40.4-0.4-0.40.4-0.4-0.50.5-0.50.5-0.5-0.6-0.4-0.4-0.40.40.6-0.30.3-0.50.70.7-1.0
Zn content in liver1.92.13.0-1.3-1.31.41.3-1.31.41.4-1.41.4-1.41.41.41.41.41.4-1.4-1.61.4-1.41.6-1.7-1.71.7
Bone: minimum diameter0.50.91.51.01.0-1.0-1.01.0-0.9-1.00.9-0.90.9-1.0-1.0-0.9-0.9-0.80.81.0-0.90.9-1.01.11.1-1.2
Time in familiar zone, hab. session 10.60.60.8-0.6-0.60.70.7-0.70.70.8-0.80.8-0.80.80.80.80.90.9-0.9-0.70.8-0.80.7-0.7-0.60.8
Time in novel zone, hab. session 10.80.71.3-0.9-0.90.80.9-0.90.80.9-0.80.8-0.90.90.90.80.70.8-0.8-0.90.8-0.80.9-1.0-1.01.2
Total zone transitions, hab. session 12.53.55.01.81.8-1.8-1.81.8-1.8-2.01.9-1.92.0-2.0-2.1-1.7-1.9-1.91.91.9-1.71.7-1.71.91.9-2.2
Total locomotion distance, hab. session 10.00.00.30.20.2-0.3-0.20.2-0.1-0.30.2-0.20.3-0.3-0.3-0.0-0.2-0.20.10.10.0-0.00.00.10.2-0.5
Locomotion velocity, hab. session 10.60.91.81.01.0-1.1-1.01.0-0.9-1.11.0-1.01.0-1.0-1.1-0.8-0.9-0.90.90.9-0.70.7-0.70.90.9-1.4
Time in familiar zone, hab. session 20.60.61.2-0.6-0.60.60.6-0.60.70.8-0.80.8-0.80.80.90.80.80.8-0.8-0.90.9-0.90.9-0.9-0.91.1
Time in novel zone, hab. session 20.00.00.1-0.3-0.30.20.3-0.30.20.1-0.20.2-0.10.10.10.10.10.2-0.1-0.10.0-0.00.1-0.1-0.1-0.1
Total zone transitions, hab. session 20.60.80.90.90.9-0.9-1.01.0-0.9-1.00.9-0.90.9-0.9-1.0-0.8-0.9-0.90.90.9-0.80.8-0.80.80.9-0.9
Total locomotion distance, hab. session 20.10.10.20.40.4-0.4-0.50.5-0.3-0.30.3-0.30.3-0.3-0.3-0.1-0.2-0.20.20.1-0.10.1-0.00.00.10.0
Locomotion velocity, hab. session 20.20.30.50.70.7-0.7-0.70.7-0.5-0.60.5-0.50.6-0.6-0.6-0.4-0.4-0.40.40.4-0.30.3-0.30.30.4-0.4
Novel to familiar place preference ratio1.91.93.01.11.1-1.1-1.21.2-1.2-1.31.3-1.31.3-1.3-1.4-1.5-1.3-1.31.41.6-1.61.6-1.61.61.7-1.7
Novelty place preference1.21.22.30.90.9-0.8-0.90.9-0.9-1.01.0-1.01.0-1.0-1.1-1.2-0.9-0.91.01.3-1.31.3-1.31.41.4-1.5
Time in novel zone, NPP test0.40.41.00.40.4-0.3-0.40.4-0.4-0.50.5-0.50.5-0.5-0.6-0.7-0.5-0.50.50.8-0.80.8-0.80.80.9-1.0
Total zone transitions, NPP test0.40.51.10.70.7-0.8-0.70.7-0.7-0.80.8-0.80.8-0.8-0.9-0.6-0.7-0.70.70.7-0.50.5-0.50.70.7-1.0
Total locomotion distance, NPP test0.00.00.1-0.0-0.00.0-0.00.00.1-0.0-0.00.00.0-0.0-0.10.2-0.00.0-0.1-0.10.3-0.30.3-0.2-0.1-0.1
Locomotion velocity, NPP test0.30.40.70.60.6-0.7-0.70.7-0.6-0.70.7-0.70.7-0.7-0.8-0.4-0.7-0.60.60.5-0.40.4-0.40.50.5-0.9
Intraocular pressure1.41.92.91.41.4-1.4-1.41.4-1.2-1.41.3-1.31.3-1.3-1.4-1.5-1.1-1.11.21.5-1.51.5-1.51.51.6-1.7
Delta distance traveled before/after self-admin1.11.21.71.31.3-1.2-1.11.1-1.1-1.01.0-1.01.0-1.0-0.8-1.2-1.0-1.01.01.1-1.31.3-1.31.11.1-0.4
Delta ambulatory time before/after self-admin0.30.30.60.80.8-0.7-0.70.7-0.6-0.40.5-0.50.4-0.4-0.3-0.7-0.5-0.50.50.5-0.70.7-0.70.50.5-0.0
Parametrial fat weight0.71.42.4-0.7-0.70.80.8-0.81.11.0-1.11.1-1.11.11.11.21.41.4-1.3-1.51.4-1.41.5-1.4-1.61.1
Pavlov. Cond. lever latency3.03.84.42.02.0-2.0-2.02.0-2.0-1.91.9-1.91.9-1.9-1.8-2.1-1.9-1.92.02.0-2.12.1-2.11.92.0-1.5
Pavlov. Cond. magazine entry latency10.012.914.5-3.7-3.73.83.8-3.83.83.7-3.73.7-3.73.73.63.63.63.7-3.6-3.53.5-3.53.5-3.4-3.33.0
Pavlov. Cond. change in total contacts7.27.79.6-3.1-3.13.13.1-3.13.02.9-2.92.9-2.92.92.72.72.82.8-2.8-2.52.5-2.52.5-2.3-2.31.9
Pavlov. Cond. index score8.610.911.9-3.4-3.43.53.4-3.43.43.3-3.43.4-3.33.33.23.33.33.3-3.3-3.33.3-3.33.3-3.1-3.12.7
Pavlov. Cond. latency score6.78.59.6-3.1-3.13.13.1-3.13.02.9-3.03.0-2.92.92.82.92.92.9-2.9-2.92.9-2.92.9-2.8-2.82.3
Pavlov. Cond. lever contacts2.63.13.4-1.8-1.81.81.8-1.81.81.7-1.81.8-1.71.71.61.81.71.7-1.8-1.81.8-1.81.8-1.7-1.71.3
Pavlov. Cond. magazine entry number12.515.617.94.24.2-4.2-4.24.2-4.1-4.14.1-4.14.0-4.0-3.9-3.9-3.9-3.93.93.8-3.83.8-3.83.73.7-3.4
Pavlov. Cond. intertrial magazine entries1.51.92.11.31.3-1.4-1.31.3-1.4-1.41.4-1.41.4-1.4-1.4-1.3-1.4-1.41.41.4-1.31.3-1.31.41.3-1.3
Pavlov. Cond. lever-magazine prob. diff.9.712.113.2-3.6-3.63.63.6-3.63.63.5-3.63.5-3.53.53.43.53.53.5-3.5-3.43.4-3.43.4-3.3-3.32.8
Pavlov. Cond. response bias9.611.712.7-3.5-3.53.63.5-3.53.53.5-3.53.5-3.53.53.43.43.43.4-3.4-3.43.4-3.43.4-3.3-3.32.9
Pavlov. Cond. lever latency0.20.30.40.60.6-0.6-0.60.6-0.5-0.60.5-0.50.5-0.5-0.6-0.5-0.5-0.40.40.7-0.40.4-0.50.70.6-0.7
Pavlov. Cond. magazine entry latency0.10.10.40.00.0-0.0-0.00.0-0.1-0.20.2-0.20.2-0.2-0.3-0.1-0.2-0.30.20.3-0.10.1-0.20.30.3-0.6
Pavlov. Cond. change in total contacts0.50.71.0-0.8-0.80.70.8-0.80.70.8-0.80.8-0.80.80.80.90.80.7-0.7-1.00.9-0.90.9-1.0-1.00.9
Pavlov. Cond. index score0.10.20.3-0.6-0.60.50.6-0.60.40.4-0.40.4-0.40.40.40.50.40.3-0.3-0.40.4-0.40.4-0.4-0.40.2
Pavlov. Cond. latency score0.10.10.2-0.4-0.40.40.4-0.40.30.3-0.30.3-0.30.30.20.30.30.2-0.2-0.30.3-0.30.3-0.2-0.20.0
Pavlov. Cond. lever contacts0.81.11.4-1.1-1.11.01.1-1.11.01.1-1.01.0-1.01.01.11.01.10.9-1.0-1.20.9-0.91.0-1.2-1.11.1
Pavlov. Cond. magazine entry number0.10.10.20.40.4-0.4-0.40.4-0.4-0.30.3-0.30.3-0.3-0.2-0.5-0.3-0.20.30.4-0.50.5-0.50.30.30.0
Pavlov. Cond. intertrial magazine entries1.41.82.01.41.4-1.4-1.41.4-1.4-1.41.4-1.41.4-1.4-1.4-1.3-1.4-1.31.31.3-1.31.3-1.21.31.2-1.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.4-0.40.40.4-0.40.30.3-0.30.3-0.30.30.20.30.20.1-0.2-0.30.3-0.30.3-0.3-0.20.1
Pavlov. Cond. response bias0.91.31.6-1.2-1.21.21.2-1.21.11.1-1.11.1-1.11.11.11.11.10.9-1.0-1.21.0-1.01.1-1.2-1.21.0
Time in closed arm before self-admin1.51.73.4-1.0-1.01.01.1-1.11.21.2-1.21.2-1.21.21.31.31.11.2-1.2-1.81.3-1.31.5-1.6-1.81.4
Time in closed arm after self-admin0.50.60.80.90.9-0.8-0.70.7-0.8-0.80.8-0.80.8-0.8-0.7-0.8-0.9-0.80.80.3-0.80.8-0.70.50.3-0.6
Time in open arm before self-admin3.13.33.82.02.0-1.8-1.81.8-1.9-1.81.8-1.81.8-1.8-1.8-1.9-1.7-1.81.81.9-1.91.9-1.91.71.9-1.3
Time in open arm after self-admin0.40.50.80.80.8-0.8-0.90.9-0.8-0.70.7-0.70.7-0.7-0.6-0.5-0.7-0.70.60.8-0.50.5-0.50.50.7-0.0
Bone: periosteal estimation0.20.30.40.60.6-0.6-0.60.6-0.6-0.60.6-0.60.6-0.6-0.6-0.5-0.6-0.50.50.5-0.50.5-0.60.60.5-0.7
Bone: periosteal perimeter0.61.01.11.01.0-1.0-1.01.0-1.0-1.01.0-1.01.0-1.0-1.0-0.9-1.0-1.01.01.0-0.90.9-1.01.00.9-0.9
Bone: post-yield work0.91.21.71.21.2-1.3-1.21.2-1.1-1.11.1-1.11.1-1.1-1.1-1.0-1.1-0.90.91.1-1.01.0-1.11.11.1-0.9
Progressive ratio test 1 active lever presses1.11.11.4-1.2-1.21.11.1-1.11.21.1-1.11.1-1.11.11.01.11.21.1-1.0-1.01.1-1.11.1-1.0-1.00.7
Progressive ratio test 1 breakpoint1.11.11.5-1.0-1.01.01.0-1.01.21.0-1.11.1-1.11.11.01.11.21.1-1.1-1.01.2-1.21.2-1.1-1.00.7
Progressive ratio test 1 inactive lever presses1.21.42.3-0.9-0.90.90.8-0.81.11.0-1.11.1-1.11.11.11.31.31.1-1.1-1.41.5-1.51.5-1.4-1.51.1
Progressive ratio test 2 active lever presses1.11.21.6-1.1-1.11.11.1-1.11.11.1-1.11.1-1.11.11.11.11.21.1-1.0-1.01.3-1.31.1-1.0-1.01.0
Progressive ratio test 2 breakpoint1.01.11.5-1.1-1.11.11.1-1.11.11.1-1.11.1-1.11.11.01.11.21.1-1.0-0.91.2-1.20.9-0.8-0.80.8
Progressive ratio test 2 inactive lever presses0.00.00.1-0.3-0.30.30.2-0.20.10.2-0.20.2-0.20.20.20.20.30.1-0.00.00.4-0.40.0-0.00.00.2
Incentive Sensitization - Responses1.11.11.5-1.2-1.21.21.2-1.21.01.1-1.11.0-1.01.01.01.11.00.9-0.9-0.91.2-1.20.9-0.9-0.90.8
Incentive Sensitization - Breakpoint1.01.01.5-1.2-1.21.21.2-1.21.01.0-1.01.0-1.01.01.01.01.00.9-0.9-0.81.1-1.10.8-0.8-0.80.7
Sum of active levers in priming session hrs 5-60.30.30.7-0.6-0.60.50.5-0.50.70.5-0.60.6-0.60.60.50.50.70.8-0.7-0.10.5-0.50.20.10.1-0.3
Progressive ratio0.00.00.20.00.0-0.2-0.10.10.0-0.10.0-0.00.0-0.0-0.00.3-0.0-0.0-0.2-0.40.3-0.30.4-0.3-0.40.1
Food seeking constrained by brief footshock0.20.30.9-0.3-0.30.40.4-0.40.50.5-0.50.5-0.50.50.60.70.50.4-0.4-0.40.8-0.80.7-0.6-0.50.9
Seeking ratio, punishment vs. effort0.10.20.4-0.5-0.50.70.6-0.60.50.5-0.50.5-0.50.50.50.20.50.4-0.20.10.2-0.20.1-0.00.10.3
Retroperitoneal fat weight0.10.30.70.80.8-0.8-0.80.8-0.4-0.60.5-0.50.5-0.5-0.6-0.3-0.2-0.20.30.2-0.20.2-0.20.40.1-0.7
Reaction time number correct0.60.91.21.01.0-1.0-1.01.0-1.1-1.01.0-1.01.0-1.0-1.0-0.9-1.0-1.11.00.8-0.80.8-0.70.70.7-0.7
Reaction time mean minus median0.00.00.10.20.2-0.2-0.20.2-0.2-0.10.2-0.20.1-0.1-0.1-0.1-0.1-0.10.2-0.3-0.00.00.2-0.3-0.30.3
Reaction time mean minus median AUC0.50.61.3-0.6-0.60.60.6-0.60.60.7-0.70.7-0.70.70.70.80.70.7-0.7-1.10.8-0.81.0-1.1-1.11.1
Reaction time num false alarms0.71.01.4-1.0-1.01.01.0-1.01.11.0-1.11.1-1.11.01.01.01.21.1-1.1-0.71.0-1.01.0-0.9-0.70.9
Reaction time num false alarms AUC0.60.81.1-0.9-0.90.90.9-0.91.00.9-0.90.9-0.90.90.90.91.01.0-1.0-0.70.9-0.90.9-0.9-0.70.7
Reaction time trials correct on left0.60.91.21.01.0-1.0-1.01.0-1.1-1.01.0-1.01.0-1.0-1.0-0.9-1.0-1.11.00.8-0.80.8-0.70.70.7-0.7
Reaction time trials on left0.60.81.20.90.9-1.0-0.90.9-1.0-1.01.0-1.01.0-1.0-1.0-0.9-1.0-1.11.00.7-0.80.8-0.60.60.6-0.7
Reaction time mean0.00.10.4-0.3-0.30.30.2-0.20.00.2-0.10.1-0.20.20.30.0-0.0-0.00.0-0.4-0.00.00.2-0.4-0.40.6
Reaction time mean AUC0.00.00.3-0.2-0.20.20.1-0.1-0.00.1-0.00.1-0.10.10.2-0.0-0.1-0.10.1-0.3-0.10.10.1-0.3-0.30.5
Median of all reaction times0.30.40.9-0.8-0.80.80.8-0.80.50.7-0.60.6-0.60.60.70.40.40.3-0.3-0.60.3-0.30.4-0.7-0.71.0
Reaction time omissions0.70.91.1-0.9-0.90.91.0-1.01.00.9-0.90.9-0.90.90.91.01.00.7-0.9-1.01.0-1.01.0-1.0-1.00.9
Reaction time false alarm rate1.11.62.2-1.3-1.31.31.3-1.31.41.3-1.31.3-1.31.31.31.21.51.4-1.3-1.01.2-1.21.2-1.1-0.91.1
Reaction time premature initiation rate0.40.50.9-0.5-0.50.50.5-0.50.80.6-0.70.7-0.70.60.60.80.50.8-0.9-0.90.7-0.71.0-0.9-0.80.5
Reaction time premature initiations0.00.00.10.30.3-0.3-0.20.2-0.1-0.20.2-0.20.2-0.2-0.20.0-0.3-0.0-0.1-0.20.0-0.00.3-0.2-0.2-0.1
Std. dev. reaction times0.00.10.2-0.1-0.10.20.1-0.10.10.2-0.10.1-0.10.10.20.10.10.1-0.1-0.50.2-0.20.4-0.4-0.50.4
Reaction time trials completed0.60.81.20.90.9-1.0-0.90.9-1.0-1.01.0-1.01.0-1.0-1.0-0.9-1.0-1.11.00.7-0.80.8-0.60.60.6-0.7
Reaction time trials AUC0.40.60.90.80.8-0.8-0.80.8-0.9-0.90.9-0.90.9-0.9-0.9-0.8-0.9-1.00.80.6-0.70.7-0.60.50.5-0.6
Run reversals in cocaine runway, females2.32.22.71.51.5-1.6-1.61.6-1.5-1.61.5-1.51.5-1.5-1.5-1.4-1.2-1.31.41.6-1.31.3-1.51.61.6-1.6
Run reversals in cocaine runway, males0.80.81.8-0.9-0.90.90.9-0.90.70.9-0.80.8-0.90.91.00.80.70.7-0.8-0.80.8-0.80.8-1.0-0.91.3
Latency to leave start box in cocaine runway2.83.14.21.81.8-1.8-1.81.8-1.9-1.71.8-1.81.8-1.7-1.6-1.9-1.8-1.92.01.5-2.02.0-1.81.41.5-0.7
Latency to leave start box in cocaine runway, F2.32.53.51.61.6-1.7-1.61.6-1.8-1.61.7-1.71.6-1.6-1.5-1.7-1.8-1.81.91.2-1.71.7-1.51.11.2-0.5
Latency to leave start box in cocaine runway, M0.50.41.00.40.4-0.4-0.40.4-0.6-0.50.5-0.50.5-0.5-0.5-0.8-0.6-0.60.81.0-1.01.0-1.00.90.9-0.4
Std. dev. time between licks in bursts0.20.30.50.50.5-0.5-0.50.5-0.6-0.50.6-0.50.5-0.5-0.4-0.5-0.6-0.70.60.3-0.60.6-0.40.30.30.1
Total sessions with >9 infusions0.80.91.2-0.9-0.90.80.7-0.71.00.9-1.01.0-1.01.00.91.01.11.0-1.0-0.81.1-1.11.0-0.9-0.80.8
Short access day 1 total inactive lever presses1.61.83.0-1.1-1.11.11.0-1.01.41.2-1.31.3-1.31.31.31.51.71.6-1.4-1.51.7-1.71.5-1.3-1.60.8
Short access day 10 total inactive lever presses0.40.40.90.80.8-0.9-1.01.0-0.8-0.80.7-0.70.7-0.7-0.6-0.5-0.5-0.60.70.3-0.40.4-0.40.30.2-0.3
Short access day 1 total infusions0.10.10.4-0.2-0.20.20.2-0.20.40.4-0.40.4-0.40.40.40.30.50.6-0.5-0.40.4-0.40.3-0.3-0.40.3
Short access day 10 total infusions0.10.10.2-0.4-0.40.40.3-0.30.40.4-0.40.4-0.40.40.40.20.50.5-0.4-0.00.2-0.2-0.10.00.00.2
Short access total infusions0.00.00.00.20.2-0.1-0.20.20.0-0.0-0.00.0-0.00.00.0-0.00.10.2-0.10.10.1-0.1-0.10.10.1-0.0
Short access day 1 locomotion2.22.42.7-1.5-1.51.61.6-1.61.61.6-1.61.6-1.61.61.51.71.51.5-1.5-1.51.5-1.51.6-1.4-1.51.2
Short access day 10 total locomotion1.92.12.5-1.5-1.51.51.2-1.21.51.5-1.51.5-1.51.51.51.51.51.6-1.6-1.31.4-1.41.5-1.4-1.31.4
Short access total locomotion0.60.61.0-0.4-0.40.50.3-0.30.70.6-0.70.7-0.70.70.80.90.90.9-0.9-0.80.9-0.91.0-0.9-0.80.9
One hour access (0.3 mA shock)0.10.10.30.10.1-0.0-0.00.00.30.1-0.20.2-0.20.20.20.20.50.4-0.3-0.40.3-0.30.2-0.3-0.40.1
Compulsive drug intake0.10.10.60.30.3-0.4-0.30.3-0.1-0.40.2-0.20.3-0.3-0.40.1-0.0-0.10.1-0.2-0.00.00.20.1-0.2-0.8
One hour access (shock baseline)0.30.31.0-0.2-0.20.30.3-0.30.40.5-0.50.5-0.60.60.70.40.80.7-0.6-0.60.6-0.60.5-0.7-0.61.0
Social response proportion0.10.10.5-0.0-0.0-0.00.0-0.00.2-0.1-0.10.1-0.00.0-0.10.50.20.1-0.3-0.30.6-0.60.7-0.4-0.3-0.1
Social responses0.10.20.4-0.3-0.30.20.3-0.30.30.3-0.30.3-0.30.30.30.60.40.3-0.4-0.40.6-0.60.6-0.5-0.30.5
Social time0.00.00.40.10.1-0.1-0.10.1-0.10.00.00.0-0.00.00.10.10.00.10.0-0.10.1-0.10.1-0.2-0.10.6
Soleus weight0.51.51.8-1.3-1.31.31.3-1.31.21.2-1.21.2-1.21.21.21.31.11.1-1.2-1.31.2-1.21.2-1.3-1.31.1
Bone: stiffness0.00.10.1-0.2-0.20.20.2-0.20.30.2-0.30.3-0.30.30.20.30.20.4-0.3-0.10.3-0.30.3-0.1-0.00.0
Tibialis anterior weight1.34.55.51.91.9-1.9-1.91.9-2.1-2.12.2-2.22.2-2.2-2.2-2.2-2.2-2.22.22.1-2.12.1-2.22.32.1-2.3
Time to tail flick, vehicle, before self-admin0.10.10.3-0.5-0.50.40.4-0.40.40.4-0.40.4-0.40.40.30.20.60.5-0.3-0.10.1-0.10.00.0-0.0-0.1
Time to tail flick, vehicle, after self-admin0.10.10.3-0.5-0.50.50.5-0.50.30.4-0.30.3-0.30.30.30.30.20.1-0.2-0.30.2-0.20.3-0.2-0.30.5
Time to tail flick, test, before self-admin0.60.60.91.01.0-0.8-0.90.9-0.8-0.80.8-0.80.7-0.7-0.7-0.8-0.7-0.60.60.9-0.70.7-0.80.80.8-0.7
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.30.40.4-0.40.20.2-0.10.1-0.10.10.0-0.2-0.00.00.10.4-0.40.4-0.30.40.5-0.3
Delta time to tail flick, vehicle, before/after SA0.40.40.7-0.6-0.60.60.6-0.60.60.6-0.60.6-0.60.60.60.80.50.5-0.7-0.50.8-0.80.7-0.7-0.60.9
Delta time to tail flick, test, before/after SA1.51.32.5-1.6-1.61.51.6-1.61.31.2-1.21.2-1.11.11.01.11.01.0-1.0-1.00.9-0.91.0-0.9-0.90.4
Tibia length0.82.22.91.41.4-1.4-1.41.4-1.5-1.51.5-1.51.5-1.5-1.5-1.5-1.6-1.51.51.6-1.41.4-1.61.71.6-1.6
Ambulatory time before self-admin0.30.30.50.70.7-0.7-0.70.7-0.6-0.70.6-0.60.7-0.7-0.6-0.3-0.4-0.40.50.4-0.20.2-0.10.20.3-0.4
Ambulatory time after self-admin3.13.44.42.12.1-2.1-2.02.0-1.9-1.81.8-1.81.8-1.8-1.7-1.9-1.7-1.71.71.8-2.02.0-1.81.71.8-1.2
Bone: tissue strength0.40.40.70.50.5-0.6-0.50.5-0.6-0.50.6-0.60.6-0.6-0.5-0.8-0.8-0.70.70.7-0.80.8-0.80.70.7-0.4
Total heroin consumption0.20.20.5-0.7-0.70.70.7-0.70.60.6-0.50.5-0.50.50.40.20.50.5-0.4-0.00.0-0.00.1-0.0-0.10.0
Bone: trabecular number4.87.48.6-2.9-2.92.92.9-2.92.82.9-2.82.8-2.82.82.82.62.62.7-2.6-2.72.5-2.52.5-2.5-2.72.4
Bone: trabecular spacing0.70.91.71.11.1-1.3-1.11.1-1.0-1.01.0-1.00.9-0.9-0.9-0.8-0.9-0.90.80.9-0.70.7-0.70.60.9-0.3
Bone: trabecular thickness0.00.00.1-0.3-0.30.30.3-0.30.10.2-0.10.1-0.10.10.1-0.0-0.1-0.00.0-0.1-0.10.1-0.10.0-0.1-0.1
Bone: trabecular tissue density0.00.00.1-0.1-0.10.20.1-0.10.10.1-0.10.1-0.10.10.10.20.10.1-0.2-0.10.2-0.20.3-0.2-0.10.1
Water consumed over 24 hours0.00.00.0-0.1-0.10.10.1-0.10.00.00.0-0.0-0.00.00.00.2-0.1-0.10.0-0.20.1-0.10.2-0.2-0.20.1
Number of responses in last shaping day0.10.10.40.20.2-0.00.1-0.1-0.2-0.10.2-0.20.2-0.2-0.1-0.3-0.2-0.30.30.6-0.30.3-0.40.30.60.1