Hub : Genes

LOC120098966

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120098966 0.12 0.09 3.0e-04 0.03 0.01 0.04 0.03 1.9e-02 9.3e-02 1.2e-02 1.7e-02
2 NAcc gene expression LOC120098966 0.12 0.09 7.7e-13 0.11 0.12 0.11 0.12 1.9e-12 3.4e-13 1.2e-12 3.4e-13
3 Brain gene expression LOC120098966 0.07 0.05 2.5e-06 0.03 0.05 0.04 0.05 5.6e-04 3.3e-05 8.5e-05 9.5e-06
4 RMTg gene expression LOC120098966 0.25 0.15 4.5e-05 0.1 0.07 0.07 0.06 1.4e-03 5.1e-03 5.9e-03 9.2e-03
5 OFC gene expression LOC120098966 0.28 0.16 2.2e-04 0.1 0.13 0.07 0.11 2.0e-03 5.7e-04 1.2e-02 1.4e-03
6 PL gene expression LOC120098966 0.14 0.1 6.3e-14 0.1 0.12 0.11 0.12 1.7e-11 5.8e-13 2.2e-12 4.4e-13
7 Adipose gene expression LOC120098966 0.23 0.11 0.0e+00 0.23 0.23 0.23 0.23 6.9e-25 3.3e-25 1.5e-25 1.8e-25
8 LHb gene expression LOC120098966 0.5 0.18 3.1e-10 0.24 0.34 0.33 0.31 2.1e-06 9.4e-09 1.3e-08 4.9e-08
9 BLA gene expression LOC120098966 0.09 0.07 1.4e-03 0.06 0.05 0.03 0.05 6.8e-04 1.0e-03 6.7e-03 9.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.91.52.91.7-1.5-1.10.9-1.2-0.91.3-1.20.7
Area under the delay curve2.52.63.4-1.61.51.6-1.51.71.8-1.51.7-1.7
BMI with tail2.27.27.8-2.62.82.7-2.72.72.6-2.72.7-2.6
BMI without tail3.87.99.4-3.03.12.9-2.72.82.7-2.82.8-2.5
Body weight6.226.233.3-5.85.75.2-4.65.24.7-5.25.2-4.4
Weight adjusted by age2.73.04.2-1.82.01.7-1.41.81.7-1.81.9-1.5
Bone surface0.10.10.2-0.50.40.3-0.10.30.2-0.30.3-0.3
Bone volume0.10.20.3-0.30.30.4-0.50.40.4-0.40.4-0.5
Breakpoint value in progressive ratio session1.21.31.61.2-1.3-1.21.2-1.1-1.01.1-1.11.1
Number of licking bursts0.50.60.90.4-0.6-0.81.0-0.8-0.90.8-0.80.8
Context. condit. distance diff. score8.710.512.22.6-3.0-3.43.5-3.3-3.43.3-3.23.5
Locomotion velocity, session 10.30.30.50.4-0.5-0.60.7-0.6-0.70.6-0.60.7
Locomotion distance, session 10.10.10.60.8-0.6-0.30.0-0.30.00.4-0.3-0.1
Locomotion velocity, session 20.00.00.1-0.0-0.1-0.20.3-0.2-0.20.2-0.20.2
Locomotion distance, session 20.20.30.60.8-0.7-0.60.5-0.6-0.40.6-0.60.4
Locomotion velocity, session 30.20.20.4-0.10.20.5-0.60.40.6-0.40.4-0.6
Locomotion distance, session 31.41.62.01.4-1.4-1.31.1-1.3-1.11.3-1.31.1
Stereotopy head waving bouts, day 31.01.22.5-1.61.41.0-0.71.10.7-1.11.1-0.7
Stereotopy head waving duration, day 30.81.01.8-1.31.20.9-0.71.00.8-1.01.0-0.7
Locomotion velocity, session 74.85.25.82.4-2.4-2.32.2-2.3-2.22.3-2.32.1
Locomotion distance, session 73.84.96.22.5-2.4-2.21.9-2.2-2.12.2-2.22.0
Stereotopy head waving bouts, day 72.12.42.8-1.71.71.5-1.41.61.4-1.61.6-1.4
Stereotopy head waving duration, day 72.63.24.1-2.02.01.8-1.61.81.7-1.81.8-1.6
Locomotion velocity, session 80.91.12.2-0.1-0.4-1.01.5-0.9-1.30.9-0.91.4
Locomotion distance, session 84.66.77.72.2-2.4-2.72.8-2.6-2.72.7-2.62.7
Degree of sensitization distance0.60.60.90.5-0.6-0.80.9-0.8-0.90.8-0.80.9
Degree of sensitization stereotypy1.41.51.7-1.31.31.2-1.21.21.2-1.31.3-1.2
Conditioned locomotion0.40.51.0-1.00.90.6-0.50.70.5-0.70.7-0.6
Cocaine response after cond. corrected0.40.40.70.8-0.8-0.70.5-0.7-0.60.7-0.70.4
Cocaine response after cond. not corrected0.00.00.2-0.40.30.00.10.1-0.1-0.10.10.0
Cocaine response before conditioning3.23.97.2-2.72.41.9-1.52.01.5-2.02.0-1.4
Saline control response1.92.53.4-1.11.41.6-1.81.61.7-1.51.5-1.8
Bone: connectivity density2.64.25.02.2-2.2-2.11.9-2.1-1.92.1-2.11.7
Bone: cortical apparent density1.11.52.4-0.60.91.3-1.51.21.5-1.21.2-1.6
Bone: cortical area2.53.84.2-2.02.02.0-1.82.01.9-2.02.0-1.9
Bone: cortical porosity0.80.91.0-0.70.80.9-1.00.91.0-0.90.9-1.0
Bone: cortical porosity0.50.60.9-0.90.90.7-0.60.80.7-0.80.8-0.6
Bone: cortical thickness5.38.711.0-2.22.63.1-3.23.03.2-2.92.9-3.3
Bone: cortical thickness1.61.93.3-0.61.01.4-1.61.31.7-1.31.3-1.8
Bone: cortical tissue density0.91.21.9-0.50.81.1-1.31.11.3-1.01.0-1.4
Condit. Reinf. active minus inactive responses0.91.01.11.1-1.1-1.01.0-1.0-1.01.0-1.00.9
Condit. Reinf. active-inactive response ratio0.10.10.10.00.10.2-0.30.20.3-0.20.2-0.4
Condit. Reinf. active responses1.31.61.91.4-1.4-1.31.1-1.3-1.21.3-1.31.1
Condit. Reinf. inactive responses1.61.93.01.7-1.6-1.31.1-1.4-1.21.5-1.41.1
Incentive salience index mean2.32.73.21.3-1.5-1.71.8-1.7-1.81.6-1.71.7
Condit. Reinf. lever presses4.05.36.41.7-2.1-2.42.5-2.3-2.42.3-2.32.5
Condit. Reinf. active minus inactive responses1.11.42.0-1.41.41.1-1.01.21.1-1.21.2-1.0
Condit. Reinf. active-inactive response ratio2.12.23.7-1.91.81.4-1.21.51.3-1.51.5-1.2
Condit. Reinf. active responses0.00.00.0-0.00.0-0.10.0-0.0-0.10.0-0.00.1
Condit. Reinf. inactive responses1.61.92.51.6-1.5-1.41.2-1.4-1.31.4-1.41.2
Condit. Reinf. lever presses0.40.50.70.8-0.8-0.80.6-0.7-0.70.7-0.70.7
Condit. Reinf. lever reinforcers received0.00.10.10.2-0.2-0.30.3-0.3-0.30.3-0.30.3
Conditioned reinforcement - actives0.40.40.8-0.60.50.5-0.60.70.8-0.90.7-0.5
Conditioned reinforcement - inactives1.71.92.7-1.31.01.1-1.41.41.6-1.61.3-1.6
Conditioned locomotion0.00.00.20.0-0.1-0.10.00.00.1-0.20.00.5
Patch foraging indifference point 0 sec0.81.32.1-0.50.71.0-1.41.11.3-1.21.1-1.5
Patch foraging indifference point AUC2.42.83.4-1.81.81.6-1.41.71.6-1.81.7-1.7
Delay disc. indifference point, 0s delay0.30.30.6-0.80.70.5-0.30.50.5-0.50.5-0.4
Delay disc. indifference point, 16s delay2.52.53.9-1.11.21.5-1.71.62.0-1.51.6-2.0
Delay disc. indifference point, 2s delay2.02.23.4-1.81.71.5-1.21.41.4-1.31.4-1.4
Delay disc. indifference point, 24s delay0.70.71.0-0.80.60.7-0.90.91.0-0.90.9-0.9
Delay disc. indifference point, 4s delay2.52.64.5-2.11.71.6-1.31.61.5-1.51.6-1.5
Delay disc. indifference point, 8s delay0.40.40.7-0.60.50.6-0.60.70.9-0.50.7-0.8
Indifference point function ln k0.81.12.10.8-0.8-0.91.0-1.0-1.21.0-1.01.4
Indifference point function log k0.81.12.10.8-0.8-0.91.0-1.0-1.21.0-1.01.4
Patch foraging total patch changes 0 sec1.21.93.0-0.70.91.3-1.71.41.6-1.41.3-1.7
Patch foraging total patch changes 12 sec1.62.13.6-0.91.11.3-1.71.41.6-1.51.4-1.9
Patch foraging total patch changes 18 sec0.91.12.6-0.10.40.9-1.40.91.4-0.90.9-1.6
Patch foraging total patch changes 24 sec0.30.31.10.8-0.6-0.1-0.50.10.7-0.10.0-1.1
Patch foraging total patch changes 6 sec1.42.13.6-0.60.91.3-1.81.41.8-1.41.3-1.9
Patch foraging time to switch 0 sec0.10.10.60.8-0.4-0.10.0-0.30.10.3-0.3-0.3
Patch foraging water rate 0 sec0.50.71.2-0.80.80.9-1.11.00.7-0.91.0-0.6
Patch foraging water rate 12 sec0.10.10.30.5-0.4-0.1-0.50.10.10.10.0-0.0
Patch foraging water rate 18 sec0.20.30.4-0.60.60.5-0.40.50.4-0.60.5-0.3
Patch foraging water rate 24 sec1.82.53.1-1.61.71.7-1.81.71.3-1.61.7-1.3
Patch foraging water rate 6 sec0.10.10.30.10.10.3-0.60.30.2-0.10.3-0.1
Seeking ratio, delayed vs. immediate footshock0.50.60.8-0.80.90.8-0.60.70.8-0.80.7-0.8
Distance traveled before self-admin0.10.10.20.0-0.1-0.30.5-0.3-0.40.3-0.30.4
Distance traveled after self-admin0.00.10.2-0.50.3-0.0-0.10.20.10.10.20.2
Extensor digitorum longus weight0.00.10.2-0.40.2-0.10.4-0.1-0.3-0.0-0.10.3
Bone: elastic displacement0.30.30.5-0.20.40.6-0.70.60.7-0.50.5-0.7
Bone: elastic work2.43.13.3-1.71.71.8-1.71.81.8-1.81.8-1.7
Bone: endosteal estimation0.71.55.7-2.41.80.9-0.21.00.3-1.11.1-0.1
Bone: endosteal perimeter0.51.02.3-0.5-0.1-0.91.4-0.8-1.30.7-0.71.5
Epididymis fat weight4.610.616.2-1.52.43.3-4.03.24.0-3.03.1-3.9
Delta time in closed arm before/after self-admin0.20.20.4-0.50.50.6-0.30.40.3-0.20.4-0.6
Delta time in open arm before/after self-admin0.10.10.2-0.00.10.1-0.40.20.3-0.20.1-0.5
Diff in mean of infusions in LGA sessions3.33.75.52.2-2.3-2.01.5-1.9-1.91.9-1.91.5
Delay discount exponential model param2.42.53.21.6-1.5-1.51.5-1.6-1.81.5-1.61.7
Extinction: sum of active levers before priming0.40.40.80.9-0.7-0.60.5-0.6-0.40.6-0.60.2
Active lever presses in extinction session 60.00.00.20.5-0.10.0-0.20.10.2-0.00.0-0.1
Bone: final force7.812.613.3-3.33.53.7-3.63.63.6-3.53.6-3.5
Bone: final moment7.011.312.0-3.23.43.5-3.43.43.4-3.43.4-3.3
Food consumed during 24 hour testing period0.30.41.2-1.10.90.5-0.20.50.3-0.60.6-0.3
Glucose2.43.66.00.5-1.2-2.02.5-1.9-2.41.7-1.82.4
Heart weight0.10.10.2-0.40.50.4-0.30.30.2-0.30.4-0.3
Delay discount hyperbolic model param2.42.53.01.7-1.5-1.51.5-1.6-1.71.4-1.61.6
Intermittent access intake day 1-15 change0.70.71.0-1.00.90.9-0.90.90.8-0.90.9-0.6
Intermittent access intake escalation0.10.10.4-0.70.40.3-0.30.40.1-0.30.4-0.0
Intermittent access intake escalation 20.40.41.3-0.2-0.1-0.50.8-0.5-0.90.5-0.41.1
Intermitt. access day 1 inactive lever presses0.00.00.1-0.30.30.10.00.1-0.1-0.20.10.2
Intermitt. access day 15 inactive lever presses2.83.13.9-1.51.81.6-1.81.81.8-1.91.8-2.0
Intermitt. access escalation Index3.32.93.31.7-1.7-1.61.7-1.8-1.81.6-1.81.5
Intermittent access day 1 total infusions0.30.40.90.8-1.0-0.70.5-0.6-0.10.4-0.60.1
Intermittent access day 15 total infusions0.00.00.10.2-0.4-0.20.1-0.10.10.0-0.10.0
Intermittent access terminal intake (last 3 days)0.10.10.3-0.20.10.3-0.30.30.6-0.50.3-0.4
Intermittent access total infusions0.00.00.10.2-0.2-0.0-0.10.00.3-0.20.0-0.1
Intermittent access day 1 locomotion0.30.30.60.3-0.7-0.60.7-0.6-0.30.3-0.60.2
Intermittent access day 15 total locomotion0.40.40.9-0.90.60.5-0.40.60.5-0.70.7-0.3
Intermittent access total locomotion0.20.20.6-0.80.50.4-0.20.50.5-0.60.5-0.2
Intermittent access standard deviation3.13.33.7-1.71.81.9-1.91.91.8-1.91.9-1.5
Left kidney weight4.111.613.3-3.63.63.4-3.13.43.1-3.63.5-3.2
Right kidney weight3.08.412.0-3.53.33.0-2.42.92.4-3.22.9-2.2
Cocaine induced anxiety3.74.35.71.7-1.9-2.12.1-2.1-2.22.0-2.12.4
Post-drug Anxiety1.41.62.11.1-1.0-1.21.2-1.3-1.41.2-1.31.5
Baseline Anxiety0.20.20.5-0.10.40.5-0.60.50.5-0.40.4-0.7
Tail length2.88.517.5-4.23.72.9-2.12.92.1-2.92.9-1.7
Length with tail3.111.520.2-4.54.03.4-2.63.42.7-3.53.5-2.4
Length without tail2.75.98.8-3.02.72.3-1.92.42.1-2.52.5-2.1
Times rat made contact with spout0.50.61.81.4-1.1-0.60.3-0.7-0.30.7-0.70.1
Lifetime Intake0.00.00.20.2-0.2-0.1-0.10.00.4-0.20.0-0.1
Liver weight, left0.10.20.9-1.00.60.20.10.30.2-0.50.4-0.4
Liver weight, right1.52.46.7-2.62.01.3-0.81.51.0-1.61.5-0.8
Locomotor activity0.30.52.1-1.51.10.50.10.50.0-0.60.50.2
Locomotor testing distance0.00.10.3-0.50.40.10.20.1-0.1-0.20.10.2
Locomotor testing rearing0.20.30.9-1.00.70.4-0.10.40.2-0.60.4-0.1
Locomotion in novel chamber0.70.81.3-1.20.90.8-0.70.90.8-1.00.9-1.1
Locomotion in novel chamber post-restriction0.70.91.1-1.00.80.9-1.01.01.1-0.81.0-0.9
Fecal boli incidents, locomotor time 10.80.91.41.2-0.9-0.91.1-1.0-0.91.0-1.00.8
Change in fecal boli incidents, locomotor task0.50.50.8-0.90.70.6-0.70.70.4-0.70.7-0.6
Time >=10cm from walls, locomotor time 10.10.10.4-0.50.60.30.10.30.2-0.40.3-0.2
Bouts of movement, locomotor time 11.61.82.21.1-1.2-1.31.4-1.4-1.51.3-1.41.3
Total resting periods, locomotor time 10.91.01.30.7-0.9-1.01.2-1.0-1.11.0-1.01.0
Rest time, locomotor task time 10.20.20.4-0.0-0.2-0.60.6-0.4-0.70.3-0.40.6
Distance moved, locomotor task time 10.91.01.3-0.80.91.1-1.11.01.1-1.01.0-0.9
Vertical activity count, locomotor time 10.60.61.1-0.60.81.1-0.70.70.7-1.00.7-0.7
Time >=10cm from walls, locomotor time 20.10.10.2-0.20.20.10.4-0.1-0.3-0.2-0.10.3
Bouts of movement, locomotor time 20.20.31.3-1.10.70.30.20.3-0.1-0.40.30.2
Total resting periods, locomotor time 20.20.20.8-0.90.3-0.10.6-0.1-0.5-0.0-0.00.6
Rest time, locomotor task time 21.11.32.40.1-0.5-1.11.6-1.1-1.51.0-1.01.4
Distance moved, locomotor task time 21.21.42.1-0.70.91.3-1.41.21.4-1.31.2-1.2
Vertical activity count, locomotor time 20.20.20.4-0.10.20.5-0.60.40.5-0.50.4-0.3
Light reinforcement 10.20.30.9-0.20.20.4-1.00.60.5-0.40.6-0.4
Light reinforcement 20.40.51.1-1.10.70.5-0.60.80.5-0.70.8-0.4
Bone: marrow area0.71.55.7-2.41.80.9-0.21.00.4-1.11.1-0.1
Bone: maximum diameter0.10.21.2-1.10.70.10.30.2-0.2-0.30.30.2
Bone: maximum force6.210.811.3-3.23.33.4-3.23.33.3-3.33.3-3.2
Bone: maximum moment5.69.610.2-3.13.23.2-3.03.13.1-3.13.1-3.0
Mean time between licks in bursts0.81.12.10.1-0.5-1.11.5-1.0-1.40.9-0.91.5
Mean num. licks in bursts0.20.20.50.30.00.5-0.70.40.7-0.30.4-0.7
Cd content in liver0.80.91.2-0.70.81.0-1.11.01.1-0.91.0-1.1
Co content in liver2.22.63.4-1.21.41.6-1.71.61.8-1.61.6-1.8
Cu content in liver1.92.35.12.3-1.9-1.40.9-1.5-1.11.6-1.51.0
Fe content in liver0.70.81.1-0.70.70.9-1.00.91.0-0.90.9-1.0
K content in liver0.10.10.20.4-0.4-0.40.3-0.4-0.30.4-0.40.3
Mg content in liver3.53.64.21.5-1.7-2.02.0-1.9-2.01.9-1.92.0
Mn content in liver3.03.45.20.9-1.4-1.92.3-1.8-2.21.8-1.72.2
Na content in liver0.10.10.3-0.20.30.4-0.40.40.5-0.40.4-0.5
Rb content in liver1.01.21.41.1-1.2-1.11.0-1.1-1.11.1-1.11.1
Se content in liver2.12.63.80.7-1.2-1.71.9-1.6-1.91.6-1.51.9
Sr content in liver0.30.20.6-0.80.60.4-0.30.50.4-0.50.5-0.4
Zn content in liver0.00.00.10.1-0.1-0.20.2-0.2-0.20.1-0.20.2
Bone: minimum diameter0.20.31.4-1.20.80.20.30.2-0.2-0.30.30.4
Time in familiar zone, hab. session 11.71.63.92.0-1.7-1.10.7-1.2-0.81.3-1.30.7
Time in novel zone, hab. session 10.70.62.0-1.41.10.7-0.30.70.4-0.80.8-0.3
Total zone transitions, hab. session 10.50.81.11.0-1.0-0.90.8-0.9-0.70.9-0.90.7
Total locomotion distance, hab. session 10.40.60.91.0-0.9-0.70.6-0.8-0.70.7-0.80.6
Locomotion velocity, hab. session 10.10.10.40.6-0.5-0.30.2-0.4-0.20.3-0.40.2
Time in familiar zone, hab. session 20.10.10.40.6-0.5-0.30.1-0.3-0.10.3-0.30.1
Time in novel zone, hab. session 20.30.30.4-0.70.60.5-0.40.50.4-0.60.5-0.4
Total zone transitions, hab. session 20.00.00.10.10.00.2-0.30.10.3-0.10.1-0.4
Total locomotion distance, hab. session 20.81.11.71.3-1.2-1.00.8-1.0-0.91.0-1.10.8
Locomotion velocity, hab. session 20.91.31.91.4-1.3-1.10.9-1.1-1.01.1-1.10.9
Novel to familiar place preference ratio0.10.10.1-0.00.10.3-0.30.20.3-0.20.2-0.3
Novelty place preference0.20.20.2-0.30.30.4-0.50.40.4-0.40.4-0.4
Time in novel zone, NPP test0.20.20.3-0.40.50.5-0.50.50.5-0.50.5-0.5
Total zone transitions, NPP test1.11.62.01.4-1.4-1.31.2-1.3-1.21.3-1.31.1
Total locomotion distance, NPP test0.81.11.91.4-1.3-1.00.8-1.1-0.91.0-1.10.9
Locomotion velocity, NPP test1.52.13.41.8-1.7-1.41.1-1.4-1.31.5-1.51.2
Intraocular pressure0.91.31.81.3-1.1-1.11.1-1.1-0.91.3-1.10.9
Delta distance traveled before/after self-admin1.01.11.4-1.11.00.9-1.21.11.1-1.11.1-0.8
Delta ambulatory time before/after self-admin0.20.30.6-0.80.50.4-0.50.50.4-0.60.6-0.1
Parametrial fat weight2.65.26.0-2.12.52.5-2.32.32.2-2.22.3-2.1
Pavlov. Cond. lever latency1.92.43.7-0.71.11.6-1.91.51.8-1.51.5-1.8
Pavlov. Cond. magazine entry latency2.22.94.10.9-1.3-1.82.0-1.7-2.01.6-1.62.0
Pavlov. Cond. change in total contacts0.10.10.6-0.80.50.10.30.1-0.1-0.10.20.2
Pavlov. Cond. index score2.63.35.00.9-1.3-1.92.2-1.8-2.11.8-1.82.1
Pavlov. Cond. latency score1.82.33.70.6-1.0-1.61.9-1.5-1.81.4-1.41.9
Pavlov. Cond. lever contacts1.01.22.10.2-0.6-1.21.5-1.1-1.31.0-1.01.4
Pavlov. Cond. magazine entry number2.93.64.5-1.31.62.0-2.11.92.1-1.91.9-2.1
Pavlov. Cond. intertrial magazine entries0.10.10.60.8-0.50.0-0.3-0.10.20.2-0.1-0.3
Pavlov. Cond. lever-magazine prob. diff.2.93.65.21.0-1.4-2.02.3-1.9-2.21.9-1.82.2
Pavlov. Cond. response bias3.13.85.21.1-1.5-2.02.3-1.9-2.21.9-1.92.2
Pavlov. Cond. lever latency0.20.20.5-0.70.60.5-0.30.50.4-0.50.5-0.4
Pavlov. Cond. magazine entry latency0.40.50.8-0.90.90.7-0.50.70.5-0.80.7-0.5
Pavlov. Cond. change in total contacts0.30.40.6-0.40.60.6-0.70.70.7-0.70.6-0.8
Pavlov. Cond. index score0.00.00.0-0.10.10.1-0.10.10.1-0.10.1-0.1
Pavlov. Cond. latency score0.10.10.1-0.20.30.3-0.30.30.3-0.40.3-0.3
Pavlov. Cond. lever contacts0.00.00.20.5-0.2-0.0-0.2-0.00.10.0-0.1-0.2
Pavlov. Cond. magazine entry number0.40.40.50.7-0.7-0.70.6-0.7-0.60.7-0.70.6
Pavlov. Cond. intertrial magazine entries2.33.03.81.2-1.6-1.81.9-1.7-1.91.8-1.72.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.10.10.1-0.10.10.1-0.10.1-0.1
Pavlov. Cond. response bias0.00.00.10.3-0.2-0.20.1-0.2-0.10.1-0.20.1
Time in closed arm before self-admin0.00.00.00.2-0.0-0.10.1-0.10.10.1-0.10.2
Time in closed arm after self-admin1.21.32.2-0.81.01.2-1.11.11.3-1.01.1-1.5
Time in open arm before self-admin0.50.60.90.4-0.7-0.90.9-0.7-1.00.4-0.70.9
Time in open arm after self-admin1.01.11.40.9-1.2-1.21.1-1.1-1.10.8-1.10.7
Bone: periosteal estimation1.73.47.2-2.72.31.7-1.21.81.4-1.91.9-1.2
Bone: periosteal perimeter0.50.82.4-1.61.20.7-0.30.80.4-0.80.8-0.3
Bone: post-yield work0.30.40.9-0.1-0.2-0.60.9-0.6-0.80.6-0.60.9
Progressive ratio test 1 active lever presses0.10.10.20.3-0.5-0.40.4-0.40.00.1-0.4-0.1
Progressive ratio test 1 breakpoint0.10.10.20.4-0.4-0.30.4-0.30.2-0.0-0.3-0.2
Progressive ratio test 1 inactive lever presses0.10.10.40.1-0.10.1-0.30.20.7-0.30.2-0.4
Progressive ratio test 2 active lever presses0.50.51.00.9-1.0-0.80.7-0.7-0.30.7-0.70.2
Progressive ratio test 2 breakpoint0.80.91.61.3-1.3-1.00.8-0.9-0.51.0-0.90.5
Progressive ratio test 2 inactive lever presses0.30.30.7-0.50.50.4-0.30.50.8-0.70.5-0.8
Incentive Sensitization - Responses0.60.60.90.9-1.0-0.90.7-0.7-0.70.9-0.80.4
Incentive Sensitization - Breakpoint0.80.81.11.0-1.1-1.00.8-0.9-0.81.0-0.90.5
Sum of active levers in priming session hrs 5-60.50.50.60.8-0.8-0.70.6-0.6-0.60.6-0.60.6
Progressive ratio5.86.87.6-2.72.82.7-2.42.62.4-2.62.6-2.7
Food seeking constrained by brief footshock0.00.00.00.1-0.1-0.10.1-0.1-0.1-0.1-0.20.1
Seeking ratio, punishment vs. effort5.06.16.62.6-2.6-2.52.3-2.5-2.42.4-2.52.6
Retroperitoneal fat weight0.51.62.0-1.21.21.3-1.21.21.2-1.31.2-1.4
Reaction time number correct0.30.51.1-0.10.40.8-1.00.70.7-0.60.6-0.7
Reaction time mean minus median1.11.53.3-0.1-0.6-1.31.8-1.1-1.41.0-1.11.5
Reaction time mean minus median AUC1.11.52.90.3-0.8-1.31.7-1.2-1.41.0-1.11.5
Reaction time num false alarms0.30.40.7-0.90.70.6-0.60.70.3-0.70.7-0.1
Reaction time num false alarms AUC0.50.71.2-1.10.90.8-0.70.90.5-0.90.9-0.4
Reaction time trials correct on left0.30.51.1-0.10.40.8-1.00.70.7-0.60.6-0.7
Reaction time trials on left0.30.41.1-0.10.50.8-1.00.70.6-0.60.6-0.7
Reaction time mean1.62.34.00.5-1.0-1.62.0-1.5-1.81.4-1.42.0
Reaction time mean AUC1.72.33.90.4-1.0-1.62.0-1.5-1.81.3-1.41.9
Median of all reaction times1.21.72.80.5-0.9-1.31.6-1.3-1.51.2-1.21.7
Reaction time omissions0.91.32.30.2-0.7-1.21.5-1.1-1.31.1-1.11.3
Reaction time false alarm rate0.10.20.7-0.90.50.3-0.00.40.0-0.40.40.1
Reaction time premature initiation rate1.52.02.4-1.41.31.3-1.31.51.5-1.41.5-1.3
Reaction time premature initiations2.33.23.7-1.51.71.8-1.91.91.9-1.81.9-1.7
Std. dev. reaction times0.91.33.0-0.2-0.5-1.21.7-1.1-1.40.9-1.01.5
Reaction time trials completed0.30.41.1-0.10.50.8-1.00.70.6-0.60.6-0.7
Reaction time trials AUC0.30.40.9-0.00.40.7-1.00.60.6-0.60.6-0.6
Run reversals in cocaine runway, females0.40.40.70.10.30.6-0.80.60.7-0.50.5-0.8
Run reversals in cocaine runway, males0.20.20.7-0.90.60.10.40.1-0.2-0.50.20.3
Latency to leave start box in cocaine runway0.10.10.3-0.20.30.2-0.30.20.2-0.40.2-0.5
Latency to leave start box in cocaine runway, F0.20.30.40.6-0.5-0.60.5-0.6-0.40.5-0.60.3
Latency to leave start box in cocaine runway, M2.01.92.4-1.11.31.5-1.61.41.1-1.41.4-1.5
Std. dev. time between licks in bursts0.50.61.5-0.3-0.1-0.71.0-0.6-1.00.5-0.61.2
Total sessions with >9 infusions0.10.10.3-0.20.00.1-0.10.20.5-0.40.2-0.4
Short access day 1 total inactive lever presses0.10.10.2-0.4-0.2-0.50.5-0.2-0.40.0-0.20.4
Short access day 10 total inactive lever presses0.10.10.4-0.1-0.0-0.20.2-0.2-0.50.1-0.20.6
Short access day 1 total infusions0.40.40.80.6-0.9-0.80.7-0.6-0.40.3-0.60.6
Short access day 10 total infusions0.10.10.5-0.10.10.1-0.40.30.7-0.30.3-0.3
Short access total infusions0.10.10.4-0.10.00.1-0.30.30.7-0.50.3-0.3
Short access day 1 locomotion3.74.04.82.1-2.2-2.11.9-2.0-1.72.1-2.01.9
Short access day 10 total locomotion0.10.10.3-0.10.0-0.30.4-0.2-0.50.3-0.20.5
Short access total locomotion0.20.20.40.5-0.4-0.50.6-0.5-0.30.4-0.50.4
One hour access (0.3 mA shock)0.60.71.21.0-1.1-1.00.9-0.9-0.60.6-0.90.4
Compulsive drug intake3.83.84.12.0-1.9-1.91.9-2.0-2.01.9-2.01.9
One hour access (shock baseline)0.50.50.8-0.80.70.6-0.50.70.9-0.90.7-0.9
Social response proportion0.00.00.1-0.20.0-0.10.1-0.0-0.1-0.0-0.00.1
Social responses0.10.20.2-0.50.40.4-0.40.40.3-0.40.4-0.3
Social time0.40.51.5-0.4-0.1-0.71.2-0.6-0.90.4-0.51.0
Soleus weight0.20.51.3-1.00.3-0.51.0-0.4-0.90.1-0.31.1
Bone: stiffness1.72.73.0-1.41.61.7-1.71.71.7-1.71.7-1.6
Tibialis anterior weight0.10.30.60.00.30.6-0.80.50.7-0.50.5-0.7
Time to tail flick, vehicle, before self-admin0.30.30.50.1-0.4-0.40.7-0.5-0.60.5-0.50.7
Time to tail flick, vehicle, after self-admin1.41.52.10.8-0.9-1.21.4-1.2-1.31.3-1.21.5
Time to tail flick, test, before self-admin0.20.20.5-0.10.30.4-0.40.30.4-0.20.3-0.7
Time to tail flick, test, after self-admin1.51.52.10.7-1.1-1.31.4-1.3-1.41.2-1.21.4
Delta time to tail flick, vehicle, before/after SA0.80.81.11.0-0.7-0.90.9-0.9-0.81.0-0.91.0
Delta time to tail flick, test, before/after SA1.31.21.40.9-1.1-1.11.1-1.1-1.11.1-1.11.2
Tibia length1.43.98.7-2.92.51.9-1.31.91.4-2.02.0-1.2
Ambulatory time before self-admin0.00.00.1-0.30.10.10.1-0.0-0.1-0.2-0.0-0.2
Ambulatory time after self-admin0.00.00.1-0.30.1-0.10.00.1-0.0-0.00.10.3
Bone: tissue strength5.35.25.5-2.22.32.3-2.22.32.2-2.32.3-2.2
Total heroin consumption0.00.00.20.1-0.1-0.10.1-0.1-0.4-0.1-0.10.1
Bone: trabecular number0.91.32.91.7-1.5-1.10.8-1.1-0.81.2-1.20.6
Bone: trabecular spacing3.24.26.5-2.62.42.0-1.72.11.8-2.22.1-1.6
Bone: trabecular thickness0.80.91.81.3-1.2-0.90.7-1.0-0.81.0-1.00.7
Bone: trabecular tissue density2.23.03.3-1.71.81.8-1.71.81.7-1.81.8-1.6
Water consumed over 24 hours0.00.00.0-0.1-0.0-0.10.2-0.1-0.20.1-0.10.1
Number of responses in last shaping day0.10.10.3-0.60.30.3-0.20.30.5-0.30.4-0.4