Best TWAS P=2.945675e-07 · Best GWAS P=7.497146e-08 conditioned to 1.170397e-63
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL2 | Myo5c | intron excision ratio | chr8:76048107:76048861 | 0.14 | 0.07 | top1 | 1 | 0.07 | 0.00014 | -5.1 | -5.1 | 2.9e-07 | 0.82 | 0.08 | 0.48 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.