Hub : Genes

Smarce1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio XM_039086085.1 0.15 0.08 3.7e-04 0.02 0.01 0.02 0.03 9.1e-04 2.2e-02 4.8e-03 2.0e-04
2 NAcc alternative polyA XM_039086085.1 0.04 0.02 7.5e-03 0.01 0 0 0 1.7e-02 7.9e-02 3.3e-01 8.6e-02
3 PL alternative polyA XM_039086082.1 0.03 0.02 8.7e-03 0.01 0.01 0.01 0.01 7.2e-03 1.6e-02 1.0e-02 2.3e-02
4 PL alternative polyA XM_039086082.1 0.03 0.02 7.3e-03 0.02 0.01 0.01 0.01 4.8e-03 1.2e-02 7.5e-03 1.6e-02
5 Liver isoform ratio NM_001399629.1 0.07 0.08 4.5e-03 0.03 0.02 0.01 -0 3.6e-04 1.5e-03 1.0e-02 5.7e-01
6 Liver alternative polyA XM_039086085.1 0.11 0.07 3.9e-03 0.02 0.01 0.01 0.01 3.8e-03 2.0e-02 4.8e-02 2.6e-02
7 Liver alternative polyA XM_039086085.1 0.12 0.07 3.4e-03 0.02 0.01 0.01 0.01 3.9e-03 2.1e-02 5.0e-02 2.7e-02
8 Liver alternative polyA XM_039086082.1 0.12 0.07 3.5e-03 0.02 0.01 0.01 0.01 2.5e-03 2.0e-02 4.3e-02 9.9e-03
9 Liver alternative polyA XM_039086082.1 0.12 0.07 3.2e-03 0.02 0.01 0.01 0.01 2.3e-03 2.2e-02 4.6e-02 9.7e-03
10 Adipose alternative polyA XM_039086082.1 0.02 0.02 5.0e-03 0.02 0 0.01 0.02 3.9e-03 8.8e-02 8.0e-03 3.4e-03
11 PL alternative polyA XM_039086085.1 0.03 0.02 8.7e-03 0.02 0.01 0.02 0.01 5.8e-03 1.3e-02 5.5e-03 2.3e-02
12 Adipose alternative polyA XM_039086082.1 0.02 0.02 5.1e-03 0.02 0 0.01 0.02 4.1e-03 9.9e-02 8.2e-03 5.1e-03
13 Adipose alternative polyA XM_039086085.1 0.02 0.02 4.8e-03 0.02 0 0.01 0.02 3.8e-03 9.0e-02 8.1e-03 5.3e-03
14 Adipose alternative polyA XM_039086085.1 0.02 0.02 5.3e-03 0.02 0 0.01 0.02 4.2e-03 9.2e-02 1.0e-02 4.3e-03
15 Adipose isoform ratio XM_039086085.1 0.02 0.02 6.8e-03 0.02 0.01 0.01 0.01 1.1e-03 6.9e-02 1.5e-02 7.4e-03
16 Adipose gene expression Smarce1 0.05 0.04 9.9e-03 0.02 0.01 0.01 0.02 1.1e-03 3.0e-02 2.7e-02 6.1e-03
17 NAcc alternative polyA XM_039086085.1 0.04 0.03 2.8e-03 0 0.01 0 0.01 1.3e-01 2.1e-02 8.7e-02 5.0e-02
18 NAcc alternative polyA XM_039086082.1 0.04 0.03 4.4e-03 0 0.01 -0 0 1.6e-01 5.6e-02 3.8e-01 1.3e-01
19 NAcc alternative polyA XM_039086082.1 0.05 0.03 1.7e-03 0 0.01 0 0 1.9e-01 1.5e-02 9.9e-02 7.6e-02
20 Brain gene expression Smarce1 0.14 0.07 1.1e-07 0.03 0.07 0.07 0.06 6.9e-04 2.9e-07 7.8e-07 6.3e-06
21 NAcc gene expression Smarce1 0.04 0.03 7.6e-03 0.03 0.01 0.02 0.02 1.9e-04 1.6e-02 4.4e-03 7.7e-04
22 Adipose mRNA stability Smarce1 0.05 0.04 4.0e-03 0.01 0 0 0.01 6.7e-03 3.1e-01 1.6e-01 3.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density2.03.34.42.1-2.02.02.01.6-2.1-2.12.12.1-2.0-2.01.7-1.7-1.7-1.71.81.8-1.9-1.8-1.90.90.5
Area under the delay curve0.10.10.40.5-0.40.40.40.7-0.4-0.40.30.3-0.3-0.20.3-0.3-0.3-0.10.3-0.50.40.5-0.3-0.20.0
BMI with tail1.96.211.9-3.12.8-2.8-2.8-3.52.82.8-2.8-2.82.72.5-3.03.03.03.0-1.5-1.41.11.10.40.71.5
BMI without tail0.20.41.3-0.70.5-0.5-0.5-0.50.70.7-0.6-0.60.40.4-1.21.21.21.1-0.1-0.20.30.20.4-0.5-0.1
Body weight3.815.928.2-4.94.6-4.6-4.6-5.34.54.5-4.6-4.64.44.3-4.64.64.64.6-2.9-2.52.02.00.71.91.7
Weight adjusted by age0.30.31.9-0.60.6-0.6-0.6-0.70.60.6-0.2-0.20.20.6-0.10.10.10.0-0.8-0.1-0.2-0.1-1.31.40.6
Bone surface0.30.53.90.0-0.20.20.2-0.5-0.2-0.20.10.1-0.1-0.3-0.30.30.30.30.61.0-1.2-1.1-1.42.01.0
Bone volume0.61.04.50.4-0.60.60.6-0.4-0.7-0.70.50.5-0.4-0.8-0.20.20.20.21.01.5-1.6-1.6-1.82.11.6
Breakpoint value in progressive ratio session0.30.30.4-0.1-0.60.60.60.40.20.20.50.5-0.6-0.60.6-0.6-0.6-0.60.60.6-0.6-0.6-0.60.40.1
Number of licking bursts0.60.73.20.4-0.30.30.3-0.1-0.5-0.50.40.4-0.6-0.6-0.00.00.00.00.61.4-1.5-1.5-1.21.81.2
Context. condit. distance diff. score1.82.26.2-0.91.3-1.3-1.3-0.41.01.0-1.6-1.61.71.6-0.30.30.30.3-0.7-2.42.52.51.9-2.0-1.2
Locomotion velocity, session 10.40.41.1-0.80.6-0.6-0.6-1.10.60.6-0.5-0.50.70.4-0.90.90.90.90.6-0.0-0.1-0.1-0.61.00.6
Locomotion distance, session 11.82.34.7-1.61.6-1.6-1.6-2.21.41.4-1.4-1.41.61.4-2.12.12.12.1-0.6-0.50.20.2-0.61.71.2
Locomotion velocity, session 20.10.10.3-0.50.4-0.4-0.4-0.30.60.6-0.3-0.30.30.40.1-0.1-0.1-0.10.2-0.40.30.3-0.10.1-0.6
Locomotion distance, session 20.40.53.3-0.40.2-0.2-0.2-0.90.10.10.00.00.00.1-0.70.70.70.7-0.20.5-0.7-0.7-1.31.81.3
Locomotion velocity, session 30.20.20.90.2-0.10.10.10.6-0.1-0.10.20.2-0.20.10.9-0.9-0.9-0.9-0.0-0.20.20.20.1-0.4-0.9
Locomotion distance, session 30.10.10.4-0.40.6-0.6-0.6-0.30.40.4-0.4-0.40.40.6-0.20.20.20.2-0.6-0.20.10.10.00.4-0.2
Stereotopy head waving bouts, day 31.72.03.31.7-1.81.81.81.8-1.5-1.51.51.5-1.6-1.71.6-1.6-1.6-1.61.20.5-0.4-0.3-0.6-0.9-0.4
Stereotopy head waving duration, day 30.10.10.20.2-0.40.40.40.3-0.1-0.10.10.1-0.1-0.40.3-0.3-0.3-0.30.3-0.30.30.3-0.2-0.40.0
Locomotion velocity, session 71.01.12.4-1.11.2-1.2-1.2-1.31.01.0-1.2-1.20.91.0-1.21.21.21.2-1.10.2-0.3-0.3-0.01.60.5
Locomotion distance, session 70.50.63.5-0.80.8-0.8-0.8-0.80.70.7-0.8-0.80.80.8-0.90.90.90.9-1.9-0.00.0-0.10.60.70.1
Stereotopy head waving bouts, day 70.40.41.20.7-0.70.70.70.5-0.8-0.80.70.7-0.7-0.80.6-0.6-0.6-0.61.10.3-0.4-0.3-1.10.30.2
Stereotopy head waving duration, day 70.30.31.60.6-0.50.50.50.4-0.6-0.60.50.5-0.6-0.60.5-0.5-0.5-0.51.30.0-0.1-0.0-1.10.30.0
Locomotion velocity, session 86.07.210.3-3.03.1-3.1-3.1-2.72.92.9-3.1-3.13.23.2-2.52.52.52.5-1.8-2.92.82.82.0-1.0-0.5
Locomotion distance, session 80.91.32.2-1.21.3-1.3-1.3-1.41.11.1-1.3-1.31.51.4-1.01.01.01.0-0.6-1.21.11.10.10.50.3
Degree of sensitization distance1.21.23.1-1.21.0-1.0-1.0-1.01.21.2-1.2-1.21.31.1-1.21.21.21.2-1.7-0.80.80.71.3-0.2-0.1
Degree of sensitization stereotypy0.70.81.61.0-0.90.90.90.6-1.1-1.11.01.0-0.9-1.00.7-0.7-0.7-0.71.20.5-0.6-0.5-1.30.40.4
Conditioned locomotion0.10.20.70.6-0.20.20.20.7-0.5-0.50.40.4-0.5-0.20.4-0.4-0.4-0.40.5-0.00.00.1-0.20.0-0.8
Cocaine response after cond. corrected0.70.84.00.7-0.70.70.7-0.0-0.9-0.90.90.9-0.9-0.70.1-0.1-0.1-0.10.90.7-0.9-0.8-2.01.11.6
Cocaine response after cond. not corrected0.90.94.10.8-0.80.80.80.1-1.0-1.01.11.1-1.0-0.80.2-0.2-0.2-0.20.50.9-1.1-1.0-2.01.31.7
Cocaine response before conditioning0.10.10.70.3-0.30.30.30.5-0.2-0.20.30.3-0.1-0.30.4-0.4-0.4-0.4-0.90.2-0.2-0.20.4-0.2-0.2
Saline control response0.30.41.0-0.60.5-0.5-0.5-0.90.50.5-0.6-0.60.50.4-0.90.90.90.9-0.6-0.30.10.1-0.61.01.0
Bone: connectivity density2.84.46.12.4-2.32.32.32.1-2.4-2.42.52.5-2.3-2.32.1-2.1-2.1-2.11.92.0-2.0-1.9-1.90.80.1
Bone: cortical apparent density4.96.510.73.0-3.03.03.03.3-2.8-2.82.62.6-2.6-2.83.1-3.1-3.1-3.12.01.5-1.1-1.20.0-1.9-1.1
Bone: cortical area0.10.20.40.3-0.10.10.10.2-0.3-0.30.20.2-0.2-0.30.6-0.6-0.6-0.60.40.5-0.5-0.5-0.20.60.1
Bone: cortical porosity0.40.41.70.3-0.30.30.3-0.3-0.4-0.40.20.2-0.4-0.4-0.10.10.10.10.90.7-0.9-0.8-1.31.21.1
Bone: cortical porosity0.40.42.10.1-0.20.20.2-0.6-0.3-0.30.10.1-0.2-0.2-0.40.40.40.40.80.5-0.7-0.6-1.41.31.4
Bone: cortical thickness0.91.43.11.4-1.11.11.11.6-1.3-1.31.21.2-1.2-1.11.8-1.8-1.8-1.81.00.4-0.3-0.2-0.2-0.4-0.6
Bone: cortical thickness4.55.28.92.8-2.62.62.63.0-2.6-2.62.52.5-2.4-2.42.7-2.7-2.7-2.72.40.7-0.7-0.5-1.6-0.4-0.4
Bone: cortical tissue density4.96.510.63.0-3.03.03.03.3-2.8-2.82.62.6-2.6-2.93.1-3.1-3.1-3.12.01.5-1.1-1.2-0.0-1.8-1.0
Condit. Reinf. active minus inactive responses1.11.32.51.1-1.01.01.01.6-0.9-0.91.11.1-1.1-0.91.6-1.6-1.6-1.61.50.10.10.1-0.0-1.2-1.1
Condit. Reinf. active-inactive response ratio1.41.53.41.2-1.01.01.01.8-0.9-0.91.11.1-1.1-0.81.8-1.8-1.8-1.81.30.00.20.20.3-1.3-1.6
Condit. Reinf. active responses1.11.43.01.2-1.11.11.11.5-1.0-1.01.11.1-1.1-0.91.7-1.7-1.7-1.71.50.2-0.1-0.0-0.0-1.2-0.9
Condit. Reinf. inactive responses0.20.20.30.4-0.30.30.30.1-0.5-0.50.40.4-0.4-0.40.5-0.5-0.5-0.50.50.4-0.4-0.4-0.60.10.5
Incentive salience index mean1.72.13.61.6-1.61.61.61.8-1.4-1.41.61.6-1.6-1.51.9-1.9-1.9-1.91.20.9-0.8-0.7-0.5-0.6-0.5
Condit. Reinf. lever presses0.81.01.51.0-1.21.21.21.0-1.0-1.01.11.1-1.1-1.11.1-1.1-1.1-1.1-0.11.2-1.2-1.2-0.60.40.3
Condit. Reinf. active minus inactive responses1.21.42.61.3-1.31.31.31.1-1.3-1.31.41.4-1.3-1.40.8-0.8-0.8-0.80.71.6-1.6-1.6-1.00.70.6
Condit. Reinf. active-inactive response ratio1.01.12.01.1-1.21.21.20.7-1.2-1.21.21.2-1.1-1.10.4-0.4-0.4-0.4-0.21.4-1.4-1.4-1.00.81.1
Condit. Reinf. active responses2.02.84.81.7-1.81.81.81.2-1.7-1.71.81.8-1.8-1.91.2-1.2-1.2-1.21.62.2-2.2-2.2-1.71.41.1
Condit. Reinf. inactive responses2.02.44.61.5-1.61.61.61.2-1.6-1.61.61.6-1.7-1.81.4-1.4-1.4-1.42.11.8-1.8-1.7-1.61.20.8
Condit. Reinf. lever presses0.20.30.60.5-0.40.40.40.6-0.4-0.40.40.4-0.5-0.40.7-0.7-0.7-0.70.80.4-0.4-0.4-0.30.4-0.2
Condit. Reinf. lever reinforcers received2.02.84.11.7-1.81.81.81.4-1.7-1.71.81.8-1.8-1.91.4-1.4-1.4-1.41.82.0-2.0-1.9-1.51.20.7
Conditioned reinforcement - actives0.60.61.11.0-0.90.90.91.0-0.9-0.90.70.7-1.0-0.90.8-0.8-0.8-0.8-0.60.9-0.7-0.80.00.10.2
Conditioned reinforcement - inactives1.82.03.31.8-1.71.71.71.5-1.8-1.81.71.7-1.5-1.81.2-1.2-1.2-1.2-0.41.3-1.0-1.10.5-1.1-0.3
Conditioned locomotion0.50.61.70.7-0.60.60.60.8-0.7-0.70.60.6-1.0-0.70.2-0.2-0.2-0.20.01.3-1.2-1.3-0.51.10.7
Patch foraging indifference point 0 sec1.52.54.71.8-1.61.61.62.1-1.6-1.61.61.6-1.6-1.52.2-2.2-2.2-2.2-0.21.3-1.0-1.10.2-0.3-1.1
Patch foraging indifference point AUC0.10.10.3-0.20.4-0.4-0.4-0.20.20.2-0.0-0.00.20.30.0-0.0-0.0-0.00.20.1-0.2-0.2-0.40.5-0.1
Delay disc. indifference point, 0s delay1.01.12.30.9-1.21.21.21.2-0.7-0.70.90.9-1.0-1.11.5-1.5-1.5-1.51.20.8-0.7-0.7-0.80.90.3
Delay disc. indifference point, 16s delay0.80.83.00.5-0.40.40.41.0-0.3-0.30.20.2-0.0-0.00.6-0.6-0.6-0.40.7-1.61.61.70.1-1.7-1.5
Delay disc. indifference point, 2s delay0.91.02.21.0-1.11.11.10.7-1.0-1.00.90.9-0.9-1.10.6-0.6-0.6-0.50.21.3-1.3-1.3-1.11.21.5
Delay disc. indifference point, 24s delay0.30.30.7-0.30.3-0.3-0.30.10.40.4-0.4-0.40.30.6-0.50.50.50.5-0.2-0.80.90.90.7-0.8-0.6
Delay disc. indifference point, 4s delay0.70.71.41.0-0.90.90.91.0-1.0-1.00.90.9-0.9-0.70.9-0.9-0.9-0.80.9-0.1-0.10.1-1.20.60.7
Delay disc. indifference point, 8s delay0.10.10.10.4-0.20.20.20.3-0.4-0.40.20.2-0.2-0.10.3-0.3-0.3-0.10.30.2-0.2-0.2-0.10.3-0.2
Indifference point function ln k0.20.20.9-0.10.0-0.0-0.00.50.30.3-0.3-0.30.10.20.2-0.2-0.2-0.2-0.4-0.70.80.80.9-1.0-0.8
Indifference point function log k0.20.20.9-0.10.0-0.0-0.00.50.30.3-0.3-0.30.10.20.2-0.2-0.2-0.2-0.4-0.70.80.80.9-1.0-0.8
Patch foraging total patch changes 0 sec1.11.83.51.5-1.31.31.31.8-1.4-1.41.41.4-1.3-1.21.9-1.9-1.9-1.9-0.51.2-1.0-1.00.4-0.2-1.1
Patch foraging total patch changes 12 sec4.96.39.02.8-2.62.62.62.4-2.8-2.82.92.9-2.6-2.82.3-2.3-2.3-2.31.43.0-2.9-2.9-2.11.90.6
Patch foraging total patch changes 18 sec0.50.71.80.8-0.50.50.50.9-0.8-0.80.90.9-0.9-0.70.9-0.9-0.9-0.90.31.4-1.2-1.3-0.30.7-0.6
Patch foraging total patch changes 24 sec1.31.62.31.5-1.11.11.11.4-1.5-1.51.41.4-1.3-1.21.5-1.5-1.5-1.50.91.2-1.2-1.1-1.11.0-0.5
Patch foraging total patch changes 6 sec1.62.33.51.8-1.61.61.61.8-1.8-1.81.71.7-1.6-1.51.9-1.9-1.9-1.9-0.21.3-1.2-1.2-0.60.2-0.3
Patch foraging time to switch 0 sec0.10.10.40.3-0.40.40.40.1-0.3-0.30.40.4-0.4-0.40.1-0.1-0.1-0.10.40.4-0.5-0.4-0.70.7-0.2
Patch foraging water rate 0 sec0.10.20.50.4-0.20.20.20.5-0.4-0.40.30.3-0.3-0.20.7-0.7-0.7-0.70.10.1-0.0-0.10.3-0.20.2
Patch foraging water rate 12 sec0.00.10.5-0.0-0.00.00.00.10.10.1-0.1-0.1-0.2-0.10.3-0.3-0.3-0.30.70.1-0.0-0.00.10.2-0.5
Patch foraging water rate 18 sec0.70.92.70.9-1.01.01.00.5-1.0-1.00.80.8-1.0-0.90.5-0.5-0.5-0.50.60.9-1.1-1.0-1.51.61.2
Patch foraging water rate 24 sec0.60.81.41.1-1.21.21.20.9-1.1-1.10.80.8-0.9-1.10.7-0.7-0.7-0.70.10.9-0.9-0.9-0.40.50.8
Patch foraging water rate 6 sec1.52.13.51.9-1.71.71.71.7-1.8-1.81.71.7-1.7-1.61.3-1.3-1.3-1.31.51.2-1.2-1.1-1.10.50.5
Seeking ratio, delayed vs. immediate footshock1.21.36.20.8-0.60.60.61.3-0.6-0.60.40.4-0.4-0.41.5-1.5-1.5-1.50.6-0.91.21.11.4-2.5-2.0
Distance traveled before self-admin0.20.22.0-0.3-0.00.00.0-0.30.30.3-0.1-0.1-0.10.2-0.10.10.10.1-0.9-0.1-0.00.0-0.50.61.4
Distance traveled after self-admin1.41.53.7-1.91.2-1.2-1.2-1.41.91.9-1.3-1.31.11.3-1.21.21.21.2-0.9-1.11.01.00.40.21.0
Extensor digitorum longus weight7.529.742.0-6.56.3-6.3-6.3-5.66.46.4-6.2-6.26.16.2-5.55.55.55.5-4.9-4.64.44.24.1-0.8-1.3
Bone: elastic displacement0.00.00.5-0.0-0.10.10.10.10.00.0-0.0-0.00.0-0.20.2-0.2-0.2-0.2-0.00.3-0.2-0.30.7-0.2-0.1
Bone: elastic work0.20.30.90.4-0.40.40.40.1-0.5-0.50.40.4-0.3-0.50.4-0.4-0.4-0.40.90.5-0.5-0.5-0.80.70.6
Bone: endosteal estimation1.94.28.8-2.42.2-2.2-2.2-3.02.02.0-2.1-2.12.11.8-2.72.72.72.7-1.2-0.2-0.1-0.1-0.42.41.5
Bone: endosteal perimeter1.02.04.0-1.71.6-1.6-1.6-2.01.61.6-1.6-1.61.61.3-1.71.71.71.7-1.0-0.0-0.0-0.10.31.30.5
Epididymis fat weight0.10.32.2-0.20.2-0.2-0.2-0.40.20.2-0.1-0.10.10.0-0.10.10.10.1-1.30.7-0.8-0.8-0.41.50.9
Delta time in closed arm before/after self-admin2.82.74.5-1.92.0-2.0-2.0-2.01.71.7-1.8-1.82.11.9-1.71.71.71.7-0.7-1.61.51.50.8-0.0-0.1
Delta time in open arm before/after self-admin0.10.11.5-0.1-0.20.20.2-0.00.10.1-0.1-0.10.1-0.1-0.00.00.00.0-0.4-0.50.50.50.4-1.20.1
Diff in mean of infusions in LGA sessions0.20.20.5-0.5-0.30.30.30.20.70.70.30.3-0.3-0.30.7-0.7-0.7-0.70.30.5-0.5-0.5-0.40.5-0.0
Delay discount exponential model param0.10.10.5-0.30.2-0.2-0.2-0.50.30.3-0.1-0.10.1-0.0-0.10.10.1-0.1-0.20.7-0.6-0.70.20.3-0.0
Extinction: sum of active levers before priming1.31.32.8-1.41.4-1.4-1.4-1.71.31.3-1.2-1.21.21.2-1.21.21.21.2-1.3-0.40.30.20.20.90.3
Active lever presses in extinction session 63.23.111.51.2-1.21.21.20.3-1.4-1.41.21.2-1.5-1.31.2-1.2-1.2-1.21.71.8-2.1-1.9-3.43.23.1
Bone: final force0.81.45.70.8-0.80.80.80.0-1.1-1.10.80.8-0.9-1.00.3-0.3-0.3-0.30.91.5-1.7-1.6-2.12.41.7
Bone: final moment0.71.15.10.6-0.60.60.6-0.2-0.9-0.90.70.7-0.7-0.80.1-0.1-0.1-0.10.71.4-1.6-1.5-1.92.31.8
Food consumed during 24 hour testing period0.60.71.3-0.90.8-0.8-0.8-1.00.80.8-1.1-1.11.00.8-0.90.90.90.9-1.2-0.60.60.50.50.30.5
Glucose0.10.20.80.0-0.20.20.2-0.1-0.1-0.1-0.0-0.00.1-0.4-0.20.20.20.20.70.5-0.6-0.6-0.60.70.9
Heart weight3.24.56.7-2.42.1-2.1-2.1-2.32.22.2-2.5-2.52.62.1-2.42.42.42.4-2.3-1.81.81.71.8-0.40.5
Delay discount hyperbolic model param0.10.10.4-0.50.4-0.4-0.4-0.60.40.4-0.2-0.20.30.1-0.30.30.30.2-0.20.5-0.5-0.50.30.1-0.2
Intermittent access intake day 1-15 change1.00.95.01.0-1.01.01.00.9-1.0-1.00.80.8-1.1-1.30.8-0.8-0.8-0.82.20.8-0.6-0.6-0.4-0.7-0.3
Intermittent access intake escalation1.11.06.91.0-1.01.01.00.9-1.0-1.00.80.8-1.1-1.30.8-0.8-0.8-0.82.60.7-0.6-0.6-0.6-0.6-0.1
Intermittent access intake escalation 20.20.22.60.4-0.30.30.30.1-0.4-0.40.30.3-0.3-0.60.0-0.0-0.0-0.01.60.6-0.5-0.5-0.4-0.00.2
Intermitt. access day 1 inactive lever presses2.02.13.11.8-1.71.71.71.5-1.8-1.81.81.8-1.6-1.61.6-1.6-1.6-1.60.50.6-0.7-0.5-1.60.20.5
Intermitt. access day 15 inactive lever presses3.74.16.22.4-2.32.32.32.5-2.3-2.32.32.3-2.4-2.32.3-2.3-2.3-2.31.91.4-1.3-1.2-0.9-0.6-0.3
Intermitt. access escalation Index1.71.52.4-1.61.4-1.4-1.4-1.51.51.5-1.4-1.41.41.5-1.21.21.21.20.3-1.21.01.1-0.30.8-0.1
Intermittent access day 1 total infusions0.20.20.70.5-0.50.50.50.4-0.5-0.50.50.5-0.4-0.30.2-0.2-0.2-0.2-0.50.2-0.2-0.2-0.30.10.8
Intermittent access day 15 total infusions0.80.92.61.1-1.11.11.11.0-1.1-1.11.01.0-1.0-1.10.9-0.9-0.9-0.91.60.1-0.1-0.0-0.6-0.80.0
Intermittent access terminal intake (last 3 days)0.80.81.51.2-1.11.11.10.9-1.2-1.21.11.1-1.1-1.10.8-0.8-0.8-0.81.00.4-0.4-0.3-0.7-0.50.3
Intermittent access total infusions0.30.30.60.8-0.60.60.60.5-0.8-0.80.70.7-0.6-0.50.4-0.4-0.4-0.40.4-0.10.10.1-0.4-0.50.3
Intermittent access day 1 locomotion0.20.20.40.5-0.40.40.40.5-0.4-0.40.40.4-0.5-0.50.3-0.3-0.3-0.3-0.50.7-0.5-0.60.30.00.2
Intermittent access day 15 total locomotion0.40.51.70.8-0.60.60.60.6-0.8-0.80.60.6-0.6-1.0-0.00.00.00.00.01.3-1.1-1.20.30.10.7
Intermittent access total locomotion0.70.71.31.0-0.90.90.91.2-1.0-1.00.90.9-1.1-1.10.7-0.7-0.7-0.70.31.1-0.8-0.90.2-0.5-0.1
Intermittent access standard deviation2.93.16.82.1-1.91.91.91.9-2.1-2.12.02.0-1.9-2.01.8-1.8-1.8-1.82.61.1-0.9-0.9-0.4-1.2-0.8
Left kidney weight0.92.45.0-1.91.8-1.8-1.8-1.42.02.0-1.8-1.81.62.0-0.60.60.60.50.0-2.22.02.20.3-0.3-1.0
Right kidney weight0.20.51.9-0.70.6-0.6-0.6-0.90.60.6-0.4-0.40.50.6-0.40.40.40.51.0-0.80.50.7-1.41.00.4
Cocaine induced anxiety1.92.23.8-1.71.5-1.5-1.5-1.91.51.5-1.4-1.41.51.7-1.81.81.81.80.2-1.20.81.0-1.11.31.4
Post-drug Anxiety0.30.31.0-0.60.5-0.5-0.5-0.70.50.5-0.5-0.50.50.8-0.50.50.50.5-0.1-1.00.80.9-0.6-0.00.5
Baseline Anxiety1.31.43.21.3-1.11.11.11.5-1.1-1.11.01.0-1.1-1.21.5-1.5-1.5-1.5-0.30.5-0.2-0.31.1-1.8-1.6
Tail length0.20.51.0-0.60.8-0.8-0.8-0.10.70.7-0.7-0.70.40.9-0.70.70.70.7-0.3-1.01.01.00.5-0.3-1.0
Length with tail1.76.19.2-2.93.0-3.0-3.0-2.72.82.8-2.9-2.92.73.0-2.22.22.22.2-2.0-2.42.22.20.81.0-0.4
Length without tail2.24.89.7-2.72.6-2.6-2.6-3.12.42.4-2.6-2.62.62.5-1.91.91.92.0-2.0-1.51.11.2-0.32.21.1
Times rat made contact with spout0.70.81.51.1-1.11.11.10.5-1.2-1.20.90.9-1.0-1.20.4-0.4-0.4-0.40.11.2-1.1-1.2-0.40.20.7
Lifetime Intake0.40.40.70.8-0.70.70.70.7-0.8-0.80.80.8-0.7-0.50.6-0.6-0.6-0.60.4-0.20.10.2-0.5-0.50.3
Liver weight, left0.00.10.20.3-0.10.10.10.3-0.3-0.30.20.2-0.3-0.20.1-0.1-0.1-0.00.00.3-0.3-0.2-0.40.4-0.0
Liver weight, right0.50.93.70.9-1.01.01.00.8-0.9-0.91.01.0-0.9-0.80.6-0.6-0.6-0.71.9-0.0-0.20.0-1.90.8-0.0
Locomotor activity0.91.54.61.0-0.90.90.90.4-1.1-1.11.11.1-1.2-1.00.5-0.5-0.5-0.51.61.6-1.7-1.7-2.02.21.3
Locomotor testing distance2.03.35.12.0-1.71.71.71.8-2.0-2.02.02.0-2.1-1.81.9-1.9-1.9-1.92.31.9-1.9-1.8-1.61.00.5
Locomotor testing rearing4.97.612.23.3-2.92.92.93.5-3.1-3.13.13.1-3.2-2.83.2-3.2-3.2-3.22.91.9-1.7-1.6-1.3-0.3-0.9
Locomotion in novel chamber3.54.36.82.4-2.62.62.62.3-2.3-2.32.42.4-2.6-2.32.3-2.3-2.3-2.21.11.2-1.2-1.0-1.7-0.21.0
Locomotion in novel chamber post-restriction1.41.65.91.0-1.31.31.30.5-1.1-1.11.01.0-1.3-1.40.7-0.7-0.7-0.60.81.8-1.8-1.9-1.31.32.4
Fecal boli incidents, locomotor time 10.50.51.3-0.80.5-0.5-0.5-0.70.70.7-0.7-0.70.50.3-1.11.11.11.1-0.90.10.0-0.10.8-0.40.5
Change in fecal boli incidents, locomotor task0.10.10.7-0.20.2-0.2-0.2-0.10.20.2-0.1-0.10.30.20.0-0.0-0.0-0.00.6-0.30.20.3-0.40.80.0
Time >=10cm from walls, locomotor time 10.40.41.60.3-0.20.20.20.7-0.1-0.10.30.3-0.3-0.11.1-1.1-1.1-1.10.6-0.10.20.20.6-0.9-1.3
Bouts of movement, locomotor time 10.30.41.1-0.51.1-1.1-1.1-0.70.40.4-0.4-0.40.31.0-0.40.40.40.4-0.5-0.40.30.3-0.30.6-0.3
Total resting periods, locomotor time 10.80.92.1-0.91.5-1.5-1.5-1.20.70.7-0.7-0.70.81.4-1.11.11.11.1-1.2-0.50.30.3-0.10.80.1
Rest time, locomotor task time 10.40.51.60.1-0.10.10.1-0.3-0.2-0.20.10.1-0.2-0.3-0.80.80.80.8-1.31.1-1.1-1.1-0.31.30.6
Distance moved, locomotor task time 10.30.42.80.1-0.40.40.40.2-0.1-0.10.00.00.0-0.10.6-0.6-0.6-0.71.7-0.90.91.0-0.3-0.9-0.2
Vertical activity count, locomotor time 10.10.10.3-0.40.3-0.3-0.3-0.30.40.4-0.3-0.30.40.3-0.30.30.30.30.6-0.50.40.50.1-0.30.2
Time >=10cm from walls, locomotor time 21.31.42.21.2-0.90.90.91.0-1.2-1.21.21.2-1.3-1.11.4-1.4-1.4-1.41.01.5-1.5-1.4-1.11.1-0.2
Bouts of movement, locomotor time 20.60.72.30.6-0.10.10.10.8-0.4-0.40.60.6-0.8-0.01.4-1.4-1.4-1.3-1.40.2-0.2-0.2-0.40.0-1.5
Total resting periods, locomotor time 20.60.62.90.40.1-0.1-0.10.8-0.3-0.30.40.4-0.60.21.3-1.3-1.3-1.3-1.6-0.10.10.1-0.2-0.3-1.7
Rest time, locomotor task time 20.70.82.9-0.91.0-1.0-1.0-0.90.80.8-0.8-0.80.80.9-1.21.21.21.1-1.7-0.40.30.30.40.2-0.1
Distance moved, locomotor task time 20.20.21.5-0.50.1-0.1-0.1-0.70.40.4-0.5-0.50.50.2-0.30.30.30.21.2-0.60.50.6-0.50.20.4
Vertical activity count, locomotor time 20.50.51.1-0.80.5-0.5-0.5-0.70.80.8-0.6-0.60.60.5-1.11.11.11.00.9-0.70.70.70.4-0.60.1
Light reinforcement 12.44.47.22.6-2.22.22.22.4-2.5-2.52.72.7-2.4-2.21.9-1.9-1.9-1.92.01.9-1.9-1.8-1.60.70.2
Light reinforcement 20.60.82.60.8-0.80.80.80.2-0.9-0.91.01.0-0.6-0.80.1-0.1-0.1-0.10.80.6-0.8-0.7-1.61.31.6
Bone: marrow area1.83.98.3-2.32.1-2.1-2.1-2.92.02.0-2.0-2.02.01.8-2.62.62.62.6-1.2-0.2-0.0-0.1-0.42.31.4
Bone: maximum diameter0.10.21.10.2-0.10.10.1-0.0-0.2-0.20.20.2-0.3-0.30.3-0.3-0.3-0.30.50.7-0.8-0.8-0.71.00.3
Bone: maximum force0.30.54.0-0.30.2-0.2-0.2-0.80.10.1-0.3-0.30.20.0-0.40.40.40.40.10.7-0.9-0.9-1.12.01.2
Bone: maximum moment0.30.53.2-0.50.4-0.4-0.4-1.00.30.3-0.4-0.40.40.2-0.60.60.60.6-0.10.5-0.7-0.7-0.91.81.2
Mean time between licks in bursts1.01.42.1-1.51.2-1.2-1.2-1.41.41.4-1.2-1.21.20.9-1.41.41.41.4-1.10.5-0.4-0.60.81.10.4
Mean num. licks in bursts0.30.43.00.4-0.50.50.50.5-0.4-0.40.20.2-0.1-0.30.3-0.3-0.3-0.3-0.5-0.70.80.80.9-1.7-0.4
Cd content in liver0.10.10.30.5-0.20.20.20.3-0.6-0.60.20.2-0.3-0.20.2-0.2-0.2-0.2-0.4-0.30.30.30.0-0.50.2
Co content in liver0.91.04.2-0.70.6-0.6-0.6-0.50.70.7-0.7-0.70.90.8-0.50.50.50.5-1.3-1.51.61.51.5-2.0-0.7
Cu content in liver0.40.42.90.3-0.10.10.10.5-0.3-0.3-0.0-0.0-0.00.30.7-0.7-0.7-0.7-0.1-0.90.91.00.8-1.7-0.8
Fe content in liver0.81.01.6-1.21.1-1.1-1.1-1.21.11.1-1.0-1.01.01.1-1.21.21.21.2-0.5-0.90.60.7-0.40.90.4
K content in liver1.61.65.61.3-1.11.11.11.3-1.2-1.21.51.5-1.4-1.11.3-1.3-1.3-1.32.40.8-0.9-0.7-1.70.70.1
Mg content in liver1.81.85.81.3-0.90.90.91.9-1.1-1.11.31.3-1.2-0.71.9-1.9-1.9-1.92.4-0.10.20.3-0.2-1.4-1.5
Mn content in liver2.83.29.02.0-1.61.61.62.2-1.8-1.81.91.9-1.8-1.62.2-2.2-2.2-2.23.01.2-1.1-1.0-1.20.0-0.8
Na content in liver0.91.04.70.4-0.50.50.5-0.2-0.6-0.60.70.7-0.7-0.6-0.20.20.20.21.61.2-1.4-1.3-2.21.81.5
Rb content in liver1.11.42.21.4-1.41.41.41.4-1.3-1.31.31.3-1.2-1.31.5-1.5-1.5-1.50.80.6-0.4-0.4-0.0-0.7-0.2
Se content in liver4.85.98.52.9-2.82.82.82.9-2.7-2.72.72.7-2.8-2.62.7-2.7-2.7-2.72.91.3-1.2-1.0-1.6-0.7-0.4
Sr content in liver0.30.30.90.5-0.30.30.30.8-0.3-0.30.30.3-0.3-0.40.7-0.7-0.7-0.7-0.3-0.00.20.10.7-0.6-1.0
Zn content in liver2.62.95.12.1-2.32.32.31.8-2.1-2.12.02.0-1.9-2.21.7-1.7-1.7-1.70.51.1-1.0-1.0-0.7-0.40.2
Bone: minimum diameter0.40.71.7-1.21.0-1.0-1.0-1.31.11.1-1.0-1.01.00.7-0.80.80.80.80.1-0.1-0.0-0.0-0.21.20.6
Time in familiar zone, hab. session 11.11.05.30.3-0.60.60.6-0.5-0.5-0.50.20.2-0.3-0.8-0.70.70.70.70.70.9-1.2-1.1-2.02.12.3
Time in novel zone, hab. session 11.41.45.10.9-0.60.60.61.5-0.6-0.60.60.6-0.6-0.51.7-1.7-1.7-1.70.3-0.10.50.31.8-2.3-1.8
Total zone transitions, hab. session 11.52.03.4-1.41.3-1.3-1.3-1.41.31.3-1.7-1.71.71.5-1.21.21.21.2-1.7-1.81.81.81.2-0.9-0.3
Total locomotion distance, hab. session 10.10.20.80.3-0.20.20.20.2-0.3-0.3-0.2-0.20.3-0.00.3-0.3-0.3-0.3-0.1-0.80.80.90.4-0.9-0.0
Locomotion velocity, hab. session 10.20.31.3-0.40.4-0.4-0.4-0.30.40.4-0.5-0.50.60.5-0.20.20.20.2-0.4-1.11.01.10.3-0.7-0.2
Time in familiar zone, hab. session 20.70.73.60.8-0.90.90.90.3-0.9-0.90.80.8-0.7-0.90.1-0.1-0.1-0.11.90.2-0.3-0.2-1.60.61.0
Time in novel zone, hab. session 20.40.41.00.4-0.30.30.30.7-0.2-0.20.40.4-0.5-0.41.0-1.0-1.0-1.0-0.80.7-0.5-0.60.8-0.4-0.9
Total zone transitions, hab. session 20.91.12.4-1.11.1-1.1-1.1-1.30.90.9-1.0-1.01.31.1-1.41.41.41.4-1.6-0.70.70.60.70.10.4
Total locomotion distance, hab. session 20.30.41.2-0.40.3-0.3-0.3-0.90.30.3-0.3-0.30.70.3-1.01.01.01.0-0.8-0.10.0-0.00.10.51.1
Locomotion velocity, hab. session 20.40.61.4-0.70.6-0.6-0.6-1.10.50.5-0.5-0.50.90.6-1.21.21.21.2-1.0-0.30.20.20.20.41.0
Novel to familiar place preference ratio1.11.12.7-1.11.2-1.2-1.2-0.41.21.2-1.0-1.00.81.4-0.30.30.30.3-0.1-1.51.41.50.6-0.9-1.7
Novelty place preference1.11.24.1-1.01.2-1.2-1.2-0.21.21.2-0.9-0.90.71.4-0.10.10.10.1-0.2-1.51.51.50.9-1.2-2.0
Time in novel zone, NPP test0.60.73.4-0.60.7-0.7-0.70.10.80.8-0.6-0.60.31.00.2-0.2-0.2-0.20.2-1.21.21.20.6-1.1-1.8
Total zone transitions, NPP test0.81.12.8-0.70.7-0.7-0.7-1.50.40.4-0.8-0.81.10.5-1.71.71.71.7-1.60.1-0.2-0.3-0.31.41.4
Total locomotion distance, NPP test0.30.42.30.0-0.20.20.2-0.8-0.3-0.3-0.0-0.00.4-0.3-0.80.80.80.8-0.60.5-0.6-0.6-0.51.21.5
Locomotion velocity, NPP test0.40.61.6-0.50.4-0.4-0.4-1.20.30.3-0.6-0.61.00.3-1.31.31.31.3-1.2-0.10.0-0.00.10.81.2
Intraocular pressure3.24.57.8-2.22.0-2.0-2.0-1.92.22.2-2.2-2.22.02.2-2.52.52.52.5-2.8-2.12.01.92.1-1.5-0.3
Delta distance traveled before/after self-admin1.41.52.1-1.41.4-1.4-1.4-1.11.41.4-1.3-1.31.31.3-1.31.31.31.30.3-1.21.21.20.9-0.5-0.7
Delta ambulatory time before/after self-admin1.21.32.3-1.41.4-1.4-1.4-1.21.41.4-1.1-1.11.11.2-1.51.51.51.50.5-0.70.60.60.20.3-0.3
Parametrial fat weight1.73.45.42.2-2.12.12.11.4-2.3-2.31.91.9-2.1-2.11.3-1.3-1.3-1.31.01.9-2.0-1.9-2.01.31.6
Pavlov. Cond. lever latency2.22.84.3-1.62.0-2.0-2.0-1.01.71.7-1.8-1.81.91.9-1.11.11.11.1-0.2-1.92.02.02.1-1.5-1.6
Pavlov. Cond. magazine entry latency7.69.914.13.6-3.83.83.82.9-3.6-3.63.63.6-3.6-3.62.9-2.9-2.9-2.92.72.9-2.9-2.7-2.80.81.3
Pavlov. Cond. change in total contacts6.56.910.73.1-3.33.33.33.2-2.9-2.92.82.8-2.9-2.93.2-3.2-3.2-3.21.31.4-1.3-1.2-1.1-0.9-0.4
Pavlov. Cond. index score6.07.611.43.1-3.43.43.42.3-3.2-3.23.13.1-3.2-3.32.3-2.3-2.3-2.31.42.8-2.9-2.8-2.51.21.7
Pavlov. Cond. latency score4.55.78.52.6-2.92.92.91.8-2.7-2.72.72.7-2.7-2.91.8-1.8-1.8-1.81.02.6-2.6-2.6-2.41.31.8
Pavlov. Cond. lever contacts1.92.33.91.4-1.81.81.80.8-1.5-1.51.51.5-1.7-1.70.9-0.9-0.9-0.9-0.21.9-2.0-1.9-1.71.61.8
Pavlov. Cond. magazine entry number9.111.317.1-4.04.1-4.1-4.1-3.34.04.0-3.8-3.83.84.0-3.23.23.23.2-2.6-2.92.82.72.5-0.3-1.2
Pavlov. Cond. intertrial magazine entries1.31.52.2-1.31.5-1.5-1.5-0.81.41.4-1.3-1.31.31.5-0.80.80.80.8-0.4-1.31.41.41.4-1.4-1.3
Pavlov. Cond. lever-magazine prob. diff.6.78.312.33.3-3.53.53.52.6-3.3-3.33.33.3-3.3-3.42.6-2.6-2.6-2.61.52.9-2.9-2.8-2.40.91.5
Pavlov. Cond. response bias6.78.212.33.4-3.53.53.52.9-3.3-3.33.23.2-3.2-3.32.9-2.9-2.9-2.91.82.4-2.4-2.3-2.20.51.0
Pavlov. Cond. lever latency0.50.71.3-0.80.8-0.8-0.8-0.60.80.8-0.7-0.70.80.9-0.80.80.80.8-1.2-1.01.01.00.6-0.7-0.6
Pavlov. Cond. magazine entry latency0.10.10.6-0.00.2-0.2-0.2-0.2-0.0-0.0-0.2-0.20.20.2-0.30.30.30.3-0.1-0.00.0-0.0-0.00.20.8
Pavlov. Cond. change in total contacts0.70.91.51.0-1.11.11.11.2-0.8-0.80.70.7-0.9-1.21.2-1.2-1.2-1.20.91.1-0.9-1.00.0-0.10.0
Pavlov. Cond. index score0.30.30.90.5-0.50.50.50.3-0.5-0.50.40.4-0.4-0.70.2-0.2-0.2-0.20.80.8-0.8-0.8-0.50.71.0
Pavlov. Cond. latency score0.20.20.80.3-0.40.40.40.1-0.4-0.40.20.2-0.3-0.50.1-0.1-0.1-0.10.60.8-0.7-0.7-0.40.60.9
Pavlov. Cond. lever contacts0.91.32.11.0-1.11.11.10.7-1.1-1.11.01.0-1.1-1.30.9-0.9-0.9-0.91.31.5-1.4-1.4-1.21.21.1
Pavlov. Cond. magazine entry number0.10.10.6-0.20.1-0.1-0.1-0.10.30.3-0.1-0.10.10.3-0.00.00.00.0-0.8-0.20.20.20.3-0.3-0.7
Pavlov. Cond. intertrial magazine entries1.52.04.2-1.41.4-1.4-1.4-0.41.61.6-1.3-1.31.31.6-0.40.40.40.4-2.1-1.71.71.71.9-1.4-2.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.90.3-0.40.40.40.2-0.4-0.40.20.2-0.3-0.60.1-0.1-0.1-0.10.70.7-0.6-0.7-0.40.61.0
Pavlov. Cond. response bias1.21.62.21.3-1.31.31.31.0-1.4-1.41.31.3-1.3-1.41.1-1.1-1.1-1.11.51.4-1.4-1.4-1.31.01.2
Time in closed arm before self-admin0.50.62.10.5-1.11.11.11.3-0.2-0.20.60.6-0.9-1.00.6-0.6-0.6-0.61.50.5-0.3-0.40.1-0.1-0.8
Time in closed arm after self-admin0.90.94.0-0.80.8-0.8-0.8-0.11.01.0-0.9-0.90.90.8-0.40.40.40.41.2-1.21.31.31.1-0.8-2.0
Time in open arm before self-admin0.80.81.7-1.01.3-1.3-1.3-1.30.90.9-1.0-1.01.21.2-0.60.60.60.6-0.9-0.70.60.6-0.10.80.2
Time in open arm after self-admin0.30.32.0-0.50.4-0.4-0.4-0.60.40.4-0.5-0.50.70.4-0.50.50.50.5-1.4-0.40.40.40.6-0.60.4
Bone: periosteal estimation0.40.83.7-0.80.8-0.8-0.8-1.30.60.6-0.7-0.70.70.5-0.90.90.90.9-0.10.5-0.6-0.6-0.81.91.1
Bone: periosteal perimeter0.61.13.2-1.11.0-1.0-1.0-1.60.90.9-1.1-1.11.00.7-1.21.21.21.2-0.30.4-0.5-0.5-0.41.81.1
Bone: post-yield work1.21.72.7-1.51.5-1.5-1.5-1.51.41.4-1.6-1.61.61.4-1.31.31.31.3-1.5-0.70.60.60.60.80.1
Progressive ratio test 1 active lever presses0.30.30.50.7-0.60.60.60.7-0.7-0.70.70.7-0.7-0.50.7-0.7-0.7-0.7-0.00.0-0.00.0-0.3-0.40.1
Progressive ratio test 1 breakpoint0.20.20.40.6-0.50.50.50.6-0.6-0.60.60.6-0.6-0.40.6-0.6-0.6-0.6-0.0-0.00.00.1-0.3-0.40.2
Progressive ratio test 1 inactive lever presses1.41.62.71.5-1.41.41.41.5-1.4-1.41.51.5-1.4-1.31.6-1.6-1.6-1.6-0.10.4-0.4-0.3-0.6-0.4-0.3
Progressive ratio test 2 active lever presses1.21.22.01.4-1.41.41.41.3-1.3-1.31.31.3-1.4-1.31.1-1.1-1.1-1.1-0.10.9-0.7-0.8-0.0-0.6-0.1
Progressive ratio test 2 breakpoint0.80.91.41.2-1.21.21.21.1-1.1-1.11.11.1-1.2-1.21.0-1.0-1.0-1.0-0.20.8-0.6-0.7-0.0-0.6-0.1
Progressive ratio test 2 inactive lever presses0.60.71.21.1-1.01.01.00.8-1.1-1.11.11.1-0.9-1.00.8-0.8-0.8-0.80.20.6-0.5-0.5-0.1-0.60.3
Incentive Sensitization - Responses1.51.52.81.4-1.51.51.51.2-1.4-1.41.41.4-1.3-1.60.8-0.8-0.8-0.8-0.51.7-1.4-1.60.3-0.30.2
Incentive Sensitization - Breakpoint1.41.42.81.4-1.41.41.41.1-1.4-1.41.31.3-1.3-1.60.8-0.8-0.8-0.8-0.31.7-1.4-1.60.2-0.20.3
Sum of active levers in priming session hrs 5-60.60.62.30.7-0.80.80.80.3-0.8-0.80.60.6-0.5-0.80.6-0.6-0.6-0.61.30.3-0.5-0.4-1.50.70.6
Progressive ratio0.20.31.30.1-0.10.10.10.2-0.1-0.10.60.6-0.5-0.2-0.10.10.10.00.60.8-0.9-0.8-1.01.10.1
Food seeking constrained by brief footshock0.40.52.40.4-0.40.40.40.2-0.5-0.50.60.6-0.5-0.5-0.10.10.10.11.20.7-0.8-0.7-1.31.60.7
Seeking ratio, punishment vs. effort0.00.00.10.00.0-0.0-0.0-0.1-0.1-0.1-0.2-0.20.30.0-0.00.00.00.00.1-0.30.40.40.4-0.30.0
Retroperitoneal fat weight0.10.20.7-0.30.4-0.4-0.4-0.70.20.2-0.3-0.30.50.4-0.70.70.70.7-0.4-0.1-0.00.0-0.40.80.8
Reaction time number correct0.50.71.9-0.80.9-0.9-0.9-1.20.60.6-0.9-0.91.00.8-0.90.90.90.9-1.4-0.10.10.00.30.81.0
Reaction time mean minus median0.40.52.8-0.80.6-0.6-0.6-0.40.90.9-0.4-0.40.50.5-0.80.80.80.8-1.7-0.10.20.01.3-0.5-0.6
Reaction time mean minus median AUC0.10.21.4-0.20.1-0.1-0.10.00.20.20.10.10.10.1-0.30.30.30.3-1.20.2-0.0-0.20.9-0.6-0.4
Reaction time num false alarms0.81.12.90.9-0.70.70.70.2-1.1-1.11.11.1-0.7-0.90.0-0.0-0.0-0.01.21.7-1.7-1.7-1.51.51.1
Reaction time num false alarms AUC0.91.24.00.8-0.60.60.60.1-0.9-0.91.01.0-0.7-0.80.1-0.1-0.1-0.11.01.9-2.0-2.0-1.41.91.2
Reaction time trials correct on left0.50.71.9-0.80.9-0.9-0.9-1.20.60.6-0.9-0.91.00.8-0.90.90.90.9-1.4-0.10.10.00.30.81.0
Reaction time trials on left0.50.71.9-0.80.8-0.8-0.8-1.20.60.6-0.9-0.91.00.8-0.90.90.90.9-1.4-0.10.0-0.00.30.81.0
Reaction time mean0.40.51.80.6-0.70.70.71.1-0.4-0.40.70.7-0.7-0.60.7-0.7-0.7-0.70.6-0.10.30.20.5-1.4-1.3
Reaction time mean AUC0.40.52.00.6-0.70.70.71.1-0.4-0.40.70.7-0.7-0.50.7-0.7-0.7-0.70.5-0.20.40.40.5-1.4-1.2
Median of all reaction times1.11.52.91.4-1.41.41.41.7-1.2-1.21.31.3-1.4-1.21.3-1.3-1.3-1.31.40.3-0.1-0.1-0.1-1.3-1.1
Reaction time omissions0.91.22.41.4-1.31.31.31.1-1.4-1.41.61.6-1.2-1.30.7-0.7-0.7-0.70.51.1-1.0-1.0-0.80.10.6
Reaction time false alarm rate0.91.33.01.0-0.90.90.90.7-1.1-1.11.31.3-1.1-1.10.5-0.5-0.5-0.51.61.7-1.7-1.7-1.41.30.5
Reaction time premature initiation rate0.60.94.70.9-0.90.90.90.8-0.9-0.90.90.9-1.0-0.70.8-0.8-0.8-0.82.2-0.20.00.3-1.60.00.8
Reaction time premature initiations0.10.21.40.2-0.20.20.2-0.1-0.3-0.30.00.0-0.1-0.10.1-0.1-0.1-0.11.0-0.50.30.4-1.00.31.2
Std. dev. reaction times0.10.10.6-0.2-0.10.10.10.20.30.30.10.1-0.1-0.1-0.10.10.10.1-0.70.3-0.1-0.20.8-0.7-0.5
Reaction time trials completed0.50.71.9-0.80.8-0.8-0.8-1.20.60.6-0.9-0.91.00.8-0.90.90.90.9-1.4-0.10.0-0.00.30.81.0
Reaction time trials AUC0.40.61.7-0.70.8-0.8-0.8-1.10.60.6-0.9-0.91.00.7-0.70.70.70.7-1.3-0.10.0-0.00.50.70.8
Run reversals in cocaine runway, females2.72.77.8-1.31.3-1.3-1.3-1.11.31.3-1.6-1.61.61.7-0.50.50.50.5-1.2-2.82.72.81.7-2.4-1.5
Run reversals in cocaine runway, males0.30.30.80.7-0.80.80.80.6-0.8-0.80.50.5-0.5-0.50.5-0.5-0.5-0.50.2-0.20.20.3-0.1-0.90.5
Latency to leave start box in cocaine runway0.91.02.0-1.21.1-1.1-1.1-1.21.11.1-1.4-1.41.41.1-0.60.60.60.6-0.2-1.01.01.00.8-0.00.0
Latency to leave start box in cocaine runway, F1.01.01.8-1.21.2-1.2-1.2-1.31.11.1-1.3-1.31.31.2-0.60.60.60.6-0.4-1.31.21.20.4-0.20.5
Latency to leave start box in cocaine runway, M0.40.31.00.5-0.40.40.40.7-0.4-0.40.10.1-0.2-0.51.0-1.0-1.0-1.01.00.2-0.0-0.10.5-0.1-0.8
Std. dev. time between licks in bursts0.20.32.2-0.20.2-0.2-0.2-0.40.10.10.00.00.0-0.1-0.30.30.30.30.31.0-1.0-1.1-0.41.50.6
Total sessions with >9 infusions0.60.71.01.0-0.90.90.91.0-1.0-1.00.90.9-0.9-0.71.0-1.0-1.0-1.00.7-0.20.20.3-0.2-0.7-0.6
Short access day 1 total inactive lever presses1.92.23.71.9-1.81.81.81.6-1.9-1.91.91.9-1.5-1.61.5-1.5-1.5-1.5-1.00.6-0.5-0.5-0.4-0.80.0
Short access day 10 total inactive lever presses0.10.10.50.1-0.00.00.0-0.2-0.2-0.20.20.20.10.1-0.00.00.00.0-0.7-0.40.30.4-0.30.1-0.3
Short access day 1 total infusions0.80.91.61.1-1.01.01.01.1-1.1-1.11.01.0-1.0-0.71.3-1.3-1.3-1.30.2-0.50.50.6-0.6-0.7-0.2
Short access day 10 total infusions0.30.40.70.7-0.70.70.70.5-0.7-0.70.80.8-0.7-0.60.3-0.3-0.3-0.30.50.4-0.5-0.4-0.80.50.8
Short access total infusions0.50.60.90.9-0.80.80.80.9-0.8-0.80.80.8-0.8-0.51.0-1.0-1.0-1.00.6-0.60.50.6-0.5-0.7-0.2
Short access day 1 locomotion3.23.45.02.2-2.22.22.22.2-2.1-2.12.22.2-2.2-2.02.1-2.1-2.1-2.10.91.2-1.1-1.1-1.10.30.1
Short access day 10 total locomotion1.11.33.51.1-1.11.11.11.2-1.1-1.11.21.2-1.3-1.50.7-0.7-0.7-0.70.21.9-1.7-1.8-0.30.60.3
Short access total locomotion0.50.51.00.9-0.80.80.81.0-0.8-0.80.80.8-0.8-0.80.8-0.8-0.8-0.8-0.20.5-0.4-0.40.4-0.4-0.7
One hour access (0.3 mA shock)0.00.00.20.1-0.10.10.10.2-0.1-0.10.10.1-0.3-0.10.2-0.2-0.2-0.20.0-0.10.10.10.3-0.5-0.4
Compulsive drug intake1.21.25.7-0.60.5-0.5-0.5-0.10.70.7-0.7-0.70.60.60.1-0.1-0.1-0.1-1.9-1.01.21.12.4-2.1-2.4
One hour access (shock baseline)0.40.51.70.8-0.60.60.60.4-0.8-0.80.70.7-0.7-0.60.4-0.4-0.4-0.41.00.5-0.6-0.5-1.30.81.1
Social response proportion0.50.50.8-0.80.8-0.8-0.8-0.90.70.7-0.9-0.90.90.9-0.60.60.60.6-0.5-0.90.80.90.1-0.0-0.1
Social responses0.20.21.9-0.1-0.20.20.2-0.4-0.0-0.00.00.0-0.0-0.2-0.30.30.30.30.30.3-0.4-0.3-1.01.41.0
Social time0.50.73.4-0.10.1-0.1-0.1-1.1-0.2-0.20.10.10.1-0.1-1.01.01.01.0-0.50.8-1.0-1.0-0.71.61.8
Soleus weight0.51.37.2-0.60.3-0.3-0.3-1.30.30.3-0.1-0.10.1-0.0-1.51.51.51.50.41.1-1.3-1.3-1.72.71.8
Bone: stiffness0.20.22.2-0.10.2-0.2-0.2-0.5-0.1-0.1-0.2-0.20.10.1-0.30.30.30.30.10.1-0.4-0.3-1.21.50.9
Tibialis anterior weight1.44.77.7-2.62.3-2.3-2.3-2.72.52.5-2.2-2.22.22.2-2.82.82.82.8-1.6-1.81.51.50.20.70.6
Time to tail flick, vehicle, before self-admin0.30.32.30.1-0.30.30.3-0.1-0.2-0.2-0.1-0.10.0-0.3-0.20.20.20.2-1.50.5-0.4-0.50.90.11.1
Time to tail flick, vehicle, after self-admin0.20.21.50.1-0.20.20.2-0.0-0.2-0.20.10.1-0.3-0.1-0.20.20.20.2-1.20.5-0.6-0.6-0.10.71.1
Time to tail flick, test, before self-admin1.01.01.8-0.91.1-1.1-1.1-1.00.80.8-1.1-1.11.11.0-1.41.41.41.4-0.5-0.70.60.60.6-0.20.1
Time to tail flick, test, after self-admin0.30.34.1-0.0-0.30.30.3-0.2-0.1-0.10.10.10.1-0.3-0.20.20.20.2-0.40.7-0.6-0.7-0.01.02.0
Delta time to tail flick, vehicle, before/after SA0.60.62.70.4-0.30.30.3-0.0-0.5-0.50.50.5-0.6-0.5-0.00.00.00.00.11.2-1.3-1.3-1.41.51.7
Delta time to tail flick, test, before/after SA1.31.22.11.0-1.41.41.41.1-1.0-1.01.31.3-1.0-1.31.1-1.1-1.1-1.1-0.11.0-0.9-1.0-0.40.51.2
Tibia length1.64.59.0-2.52.1-2.1-2.1-3.02.22.2-2.1-2.12.22.1-2.82.82.82.8-1.6-1.31.01.0-0.21.31.6
Ambulatory time before self-admin0.20.22.4-0.1-0.00.00.0-0.20.10.1-0.2-0.20.00.2-0.00.00.0-0.1-1.6-0.30.30.30.3-0.20.8
Ambulatory time after self-admin2.42.64.9-2.21.5-1.5-1.5-1.92.22.2-1.6-1.61.41.5-2.02.02.02.0-1.3-1.21.01.00.30.41.4
Bone: tissue strength0.90.92.2-1.11.2-1.2-1.2-1.01.11.1-1.0-1.01.01.1-0.90.90.90.9-1.5-0.00.1-0.01.10.4-0.1
Total heroin consumption3.33.86.81.7-2.12.12.11.0-1.9-1.91.81.8-1.7-2.31.2-1.2-1.2-1.20.92.5-2.6-2.6-2.42.32.6
Bone: trabecular number4.46.99.53.0-2.92.92.92.2-3.0-3.03.13.1-2.9-2.92.1-2.1-2.1-2.12.62.7-2.7-2.6-2.91.41.1
Bone: trabecular spacing1.72.24.3-1.61.3-1.3-1.3-2.11.31.3-1.4-1.41.51.3-2.02.02.02.0-1.7-1.00.80.80.20.71.4
Bone: trabecular thickness0.30.31.00.4-0.60.60.60.3-0.4-0.40.50.5-0.3-0.70.3-0.3-0.3-0.30.91.0-0.9-1.0-0.30.50.1
Bone: trabecular tissue density0.70.95.50.10.2-0.2-0.20.90.20.2-0.3-0.30.10.40.8-0.8-0.8-0.8-1.0-1.11.31.21.7-1.8-2.3
Water consumed over 24 hours0.10.10.3-0.00.1-0.1-0.1-0.5-0.1-0.1-0.5-0.50.4-0.0-0.30.30.30.3-0.30.4-0.3-0.40.10.50.5
Number of responses in last shaping day0.90.92.00.9-0.90.90.91.0-0.8-0.80.90.9-0.9-1.01.3-1.3-1.3-1.31.30.10.10.10.2-1.4-1.1