Hub : Genes

Apc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Apc 0.02 0.01 9.5e-04 0.03 0.02 0.02 0.03 1.1e-04 1.1e-03 2.4e-03 8.8e-04
2 Eye intron excision ratio chr18_25904466_25907713 0.26 0.14 6.1e-03 0.1 0.08 0.06 0.07 1.4e-02 2.3e-02 4.5e-02 3.7e-02
3 Brain intron excision ratio chr18_25864409_25871423 0.07 0.06 3.9e-03 0.02 0.01 -0 0.01 1.1e-02 3.0e-02 4.3e-01 4.3e-02
4 NAcc intron excision ratio chr18_25864409_25871423 0.02 0.01 8.8e-03 0.01 0.01 0.01 0.01 2.5e-02 2.3e-02 4.0e-02 6.0e-03
5 RMTg gene expression Apc 0.15 0.11 2.6e-03 0.05 0.06 0.04 0.07 1.9e-02 1.1e-02 3.6e-02 6.5e-03
6 BLA intron excision ratio chr18_25903143_25907713 0.05 0.04 6.0e-03 0.05 0.04 0.04 0.05 1.0e-03 2.5e-03 5.7e-03 1.5e-03
7 PL intron excision ratio chr18_25864409_25871423 0.04 0.03 4.0e-03 0.02 0.01 0.02 0.01 1.2e-03 1.5e-02 1.6e-03 1.1e-02
8 OFC intron excision ratio chr18_25864409_25871423 0.17 0.11 5.8e-03 0.07 0.05 0.04 0.04 1.2e-02 2.6e-02 3.6e-02 3.6e-02
9 Brain intron excision ratio chr18_25828942_25871423 0.05 0.03 1.5e-07 0.04 0.08 0.07 0.07 1.0e-04 1.3e-07 8.8e-07 8.8e-07
10 Brain intron excision ratio chr18_25869365_25871423 0.03 0.02 5.1e-04 0.04 0.03 0.04 0.04 2.9e-04 4.3e-04 1.5e-04 1.5e-04
11 BLA intron excision ratio chr18_25828942_25864257 0.09 0.06 7.7e-03 0.03 0.02 0.01 0.02 8.9e-03 3.0e-02 7.6e-02 4.6e-02
12 Brain gene expression Apc 0.05 0.03 1.8e-06 0.04 0.06 0.04 0.05 7.6e-05 6.6e-06 1.4e-04 3.3e-05
13 RMTg alternative TSS XM_006254509.4 0.09 0.07 4.6e-03 0.04 0.1 0.01 0.04 4.1e-02 1.6e-03 1.5e-01 2.4e-02
14 RMTg alternative TSS XM_006254509.4 0.09 0.06 5.8e-03 0.03 0.09 0.01 0.04 6.1e-02 2.6e-03 1.2e-01 3.9e-02
15 Liver mRNA stability Apc 0.02 0.02 4.2e-03 -0 0 -0 -0 4.8e-01 1.4e-01 7.9e-01 7.8e-01
16 Brain mRNA stability Apc 0.03 0.02 3.4e-03 0.01 0.01 0.01 0.01 4.3e-02 1.3e-02 1.8e-02 3.4e-02
17 Brain intron excision ratio chr18_25864409_25869179 0.03 0.02 2.2e-03 0.01 0.01 0.01 0.01 5.1e-02 2.4e-02 2.2e-02 5.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.40.72.6-0.81.10.4-1.10.9-0.40.40.2-0.50.51.60.7-0.6-0.60.5-0.4-1.4
Area under the delay curve3.43.66.2-2.22.12.2-2.01.7-2.42.10.6-2.21.10.92.0-1.9-1.92.3-2.5-1.0
BMI with tail5.216.929.14.6-4.5-5.44.2-4.34.5-4.3-4.34.5-4.2-4.1-4.33.73.6-3.63.30.8
BMI without tail4.39.013.33.2-3.0-3.63.2-3.33.0-3.1-3.63.1-3.4-3.4-3.02.72.6-2.42.11.3
Body weight5.121.338.35.0-4.9-6.24.6-4.75.5-5.2-4.15.1-4.8-3.8-4.74.24.1-4.24.01.2
Weight adjusted by age1.21.32.81.4-1.5-1.31.5-1.21.7-1.4-0.81.2-1.2-0.5-1.00.80.8-0.90.90.4
Bone surface0.91.63.9-1.41.70.6-1.71.4-1.11.21.2-0.91.41.61.0-0.9-0.80.8-0.6-2.0
Bone volume0.61.13.3-1.21.50.4-1.51.2-0.80.90.9-0.61.01.60.8-0.6-0.60.5-0.3-1.8
Breakpoint value in progressive ratio session0.10.10.40.3-0.30.10.4-0.50.3-0.5-0.10.2-0.0-0.4-0.20.20.2-0.30.30.6
Number of licking bursts1.31.53.2-1.51.70.9-1.51.4-0.91.01.3-1.11.31.81.1-1.1-1.01.0-0.7-1.0
Context. condit. distance diff. score0.10.10.8-0.30.50.0-0.2-0.10.00.1-0.9-0.0-0.5-0.5-0.10.10.00.2-0.30.4
Locomotion velocity, session 10.80.82.80.8-0.9-0.80.7-0.30.3-0.3-0.61.1-0.60.0-1.11.21.3-1.51.70.5
Locomotion distance, session 10.10.10.30.00.1-0.20.1-0.30.1-0.2-0.50.2-0.4-0.1-0.30.30.4-0.30.30.5
Locomotion velocity, session 20.40.51.01.0-1.0-1.00.7-0.70.4-0.6-0.00.9-0.3-0.4-0.80.70.7-0.91.0-0.4
Locomotion distance, session 20.40.61.0-1.00.90.7-1.00.8-0.90.90.7-0.71.00.70.7-0.6-0.60.6-0.5-0.7
Locomotion velocity, session 30.50.51.70.4-0.4-0.60.6-0.60.4-0.1-1.30.7-0.9-1.2-0.80.90.8-0.70.50.4
Locomotion distance, session 30.10.10.4-0.60.70.2-0.4-0.20.10.0-0.5-0.2-0.2-0.40.2-0.1-0.10.3-0.50.4
Stereotopy head waving bouts, day 32.32.75.3-1.41.41.7-1.71.8-2.22.31.7-1.61.81.31.6-1.5-1.51.4-1.4-1.3
Stereotopy head waving duration, day 30.20.31.60.2-0.20.6-0.00.5-1.31.10.2-0.40.4-0.10.3-0.3-0.30.2-0.3-0.3
Locomotion velocity, session 70.10.21.20.3-0.3-0.70.1-0.40.4-0.4-0.00.4-0.2-0.2-0.10.10.1-0.10.1-1.1
Locomotion distance, session 70.40.51.3-0.70.60.3-0.80.5-0.10.30.5-0.70.80.40.9-0.9-0.91.0-1.0-1.2
Stereotopy head waving bouts, day 70.40.41.41.2-1.1-0.40.9-0.40.5-0.6-0.80.5-0.7-0.1-0.60.40.4-0.60.60.3
Stereotopy head waving duration, day 70.10.10.50.7-0.7-0.00.6-0.00.1-0.2-0.40.3-0.40.1-0.30.20.2-0.30.30.4
Locomotion velocity, session 80.50.61.80.7-0.6-0.21.0-0.6-0.30.2-1.10.5-0.8-1.3-0.80.70.7-0.60.51.0
Locomotion distance, session 80.10.10.9-0.40.50.2-0.1-0.1-0.30.4-0.90.0-0.4-0.6-0.20.20.2-0.0-0.10.4
Degree of sensitization distance0.20.21.30.4-0.5-0.40.10.10.4-0.20.60.00.40.30.2-0.3-0.40.2-0.2-1.2
Degree of sensitization stereotypy0.20.30.70.8-0.9-0.20.7-0.10.5-0.6-0.70.3-0.60.5-0.40.20.2-0.40.50.4
Conditioned locomotion0.10.10.7-0.40.3-0.4-0.3-0.00.10.2-0.20.00.00.10.1-0.1-0.10.2-0.2-0.8
Cocaine response after cond. corrected1.41.63.90.5-0.5-1.11.0-1.21.1-1.0-1.71.2-1.2-1.7-1.31.41.4-1.21.02.0
Cocaine response after cond. not corrected0.40.54.0-0.30.3-0.10.3-0.40.6-0.4-0.80.3-0.3-1.0-0.50.70.7-0.40.42.0
Cocaine response before conditioning4.95.97.9-2.52.52.7-2.42.6-2.02.12.7-2.62.82.42.5-2.6-2.52.4-2.3-1.0
Saline control response0.71.01.6-1.11.11.1-0.90.90.1-0.31.2-1.01.31.21.1-1.1-1.00.9-0.80.5
Bone: connectivity density1.62.44.7-1.71.81.3-1.91.9-1.61.70.9-1.41.42.21.4-1.3-1.21.2-1.0-2.0
Bone: cortical apparent density1.01.32.6-0.90.81.4-1.01.3-1.01.01.6-1.21.21.41.2-1.2-1.11.0-0.9-1.0
Bone: cortical area2.84.36.5-2.42.61.9-2.52.1-1.31.62.3-2.12.41.92.2-2.1-2.12.1-2.0-1.1
Bone: cortical porosity1.01.11.81.1-1.0-0.91.2-1.00.9-0.7-0.71.1-0.9-1.2-1.11.21.2-1.21.21.4
Bone: cortical porosity0.90.92.50.9-0.9-0.81.1-0.90.8-0.6-0.70.9-0.7-1.3-0.91.01.0-1.01.01.6
Bone: cortical thickness2.74.45.8-2.22.31.7-2.42.1-1.31.62.1-2.12.22.12.3-2.3-2.32.3-2.2-1.8
Bone: cortical thickness0.40.50.9-1.01.00.5-0.80.7-0.10.20.7-0.70.60.60.8-0.8-0.80.9-0.9-0.4
Bone: cortical tissue density0.81.02.2-0.80.71.2-0.91.2-0.90.91.5-1.11.11.31.0-1.0-1.00.8-0.7-0.9
Condit. Reinf. active minus inactive responses2.02.24.6-1.51.51.6-1.61.6-2.12.10.9-1.41.41.41.3-1.2-1.21.2-1.1-1.5
Condit. Reinf. active-inactive response ratio1.41.52.1-1.21.11.2-1.21.1-1.41.30.7-1.31.10.91.3-1.3-1.31.4-1.5-1.4
Condit. Reinf. active responses1.41.73.9-1.81.81.4-1.71.6-1.82.00.8-1.11.41.20.9-0.6-0.50.6-0.4-0.8
Condit. Reinf. inactive responses0.80.92.5-1.51.60.9-1.31.4-1.11.30.9-0.61.10.90.5-0.1-0.00.00.20.3
Incentive salience index mean1.31.63.1-1.31.31.6-1.41.5-1.81.70.9-1.31.31.51.2-1.0-0.90.9-0.8-0.7
Condit. Reinf. lever presses0.71.02.2-1.11.21.5-1.01.3-0.80.70.9-1.11.11.31.0-0.9-0.80.8-0.60.4
Condit. Reinf. active minus inactive responses1.82.25.6-2.11.82.4-1.31.8-1.51.61.3-1.61.61.01.4-1.0-0.91.0-0.91.1
Condit. Reinf. active-inactive response ratio0.60.65.10.2-0.40.20.8-0.40.3-0.1-0.70.4-0.4-0.9-0.60.80.9-0.80.82.3
Condit. Reinf. active responses5.57.715.0-3.53.33.9-2.73.1-2.72.82.6-3.13.02.22.8-2.4-2.32.4-2.30.4
Condit. Reinf. inactive responses7.79.413.1-3.53.63.6-3.33.4-2.92.83.1-3.33.32.93.1-2.9-2.92.9-2.7-1.3
Condit. Reinf. lever presses1.52.03.8-2.01.91.8-1.71.7-1.11.31.7-1.41.81.21.3-1.0-1.01.0-0.90.6
Condit. Reinf. lever reinforcers received5.07.014.1-3.33.13.8-2.63.0-2.72.82.4-3.02.82.02.6-2.3-2.22.3-2.10.6
Conditioned reinforcement - actives0.40.42.8-0.0-0.30.20.5-0.50.3-0.4-0.70.2-0.5-0.4-0.50.60.6-0.50.51.7
Conditioned reinforcement - inactives0.10.10.6-0.80.40.3-0.4-0.1-0.2-0.2-0.1-0.2-0.10.80.1-0.1-0.10.2-0.3-0.3
Conditioned locomotion0.10.10.9-0.40.50.5-0.20.40.00.1-0.0-0.10.00.3-0.00.20.2-0.20.31.0
Patch foraging indifference point 0 sec1.93.05.2-2.02.32.3-1.91.8-1.51.21.4-2.01.61.21.8-1.8-1.81.9-1.9-0.1
Patch foraging indifference point AUC3.03.44.9-2.21.52.0-1.72.2-2.21.82.1-1.91.81.91.9-1.8-1.81.7-1.5-1.1
Delay disc. indifference point, 0s delay1.31.42.7-1.51.41.3-1.21.0-1.40.90.5-1.40.70.11.3-1.2-1.31.5-1.7-1.1
Delay disc. indifference point, 16s delay4.94.96.9-2.42.32.4-2.42.1-2.42.41.5-2.41.81.72.3-2.3-2.32.5-2.6-1.7
Delay disc. indifference point, 2s delay0.50.61.3-0.60.60.8-0.70.6-1.10.70.1-0.90.2-0.10.9-0.8-0.81.0-1.1-1.1
Delay disc. indifference point, 24s delay0.60.61.3-0.90.90.8-0.60.4-1.01.1-0.6-0.8-0.1-0.20.6-0.5-0.60.9-1.10.6
Delay disc. indifference point, 4s delay0.50.61.2-0.80.60.9-0.60.6-1.10.80.2-0.90.40.70.8-0.7-0.70.9-1.0-0.4
Delay disc. indifference point, 8s delay4.24.47.6-2.62.62.5-2.31.8-2.52.50.4-2.41.00.62.1-1.9-2.02.5-2.7-0.4
Indifference point function ln k7.110.015.63.5-3.3-3.53.2-3.53.9-3.7-3.03.2-2.9-3.0-3.22.92.9-2.92.71.6
Indifference point function log k7.110.015.63.5-3.3-3.53.2-3.53.9-3.7-3.03.2-2.9-3.0-3.22.92.9-2.92.71.6
Patch foraging total patch changes 0 sec1.93.05.2-2.12.32.2-1.91.7-1.61.31.6-2.01.61.31.8-1.7-1.71.8-1.8-0.5
Patch foraging total patch changes 12 sec8.711.316.6-4.13.93.7-3.73.6-3.63.33.3-3.53.23.03.4-3.2-3.23.2-3.1-1.4
Patch foraging total patch changes 18 sec4.35.58.9-3.02.82.5-2.62.6-2.62.42.0-2.42.11.92.4-2.1-2.12.3-2.2-1.7
Patch foraging total patch changes 24 sec3.34.15.5-2.32.32.1-2.22.0-1.91.72.2-2.12.11.72.1-2.0-2.02.1-2.0-1.5
Patch foraging total patch changes 6 sec3.55.27.8-2.82.72.7-2.42.5-2.21.72.3-2.52.41.82.4-2.2-2.22.3-2.2-1.0
Patch foraging time to switch 0 sec0.20.31.00.6-0.0-0.30.2-0.70.2-0.1-0.80.4-0.2-1.0-0.50.50.5-0.40.30.6
Patch foraging water rate 0 sec0.00.00.1-0.4-0.1-0.1-0.00.10.1-0.1-0.1-0.0-0.20.20.0-0.1-0.10.1-0.1-0.2
Patch foraging water rate 12 sec0.40.62.30.2-0.4-1.00.5-0.81.5-1.0-0.50.9-0.7-0.8-0.80.80.8-0.60.60.0
Patch foraging water rate 18 sec0.50.62.30.4-0.4-0.30.8-0.80.8-0.8-0.80.6-0.8-0.9-0.80.90.9-0.80.71.5
Patch foraging water rate 24 sec0.60.81.6-0.1-0.3-0.50.6-0.70.5-0.4-1.10.9-1.0-1.0-1.11.31.3-1.11.00.9
Patch foraging water rate 6 sec0.10.20.4-0.2-0.1-0.50.1-0.20.5-0.2-0.30.5-0.4-0.4-0.50.60.6-0.50.50.0
Seeking ratio, delayed vs. immediate footshock0.50.61.6-0.50.61.0-0.90.9-0.20.11.3-0.71.11.20.7-0.7-0.60.4-0.10.3
Distance traveled before self-admin0.10.10.50.3-0.20.50.2-0.2-0.40.7-0.3-0.4-0.2-0.10.4-0.3-0.40.4-0.60.5
Distance traveled after self-admin0.50.53.9-0.70.61.4-0.10.1-0.60.2-0.7-0.4-0.1-1.00.10.30.3-0.0-0.22.0
Extensor digitorum longus weight1.66.410.03.0-2.7-2.92.7-2.83.2-3.2-2.42.6-2.5-2.5-2.42.12.0-2.11.91.4
Bone: elastic displacement1.61.82.71.3-1.3-1.01.6-1.51.0-1.2-1.61.2-1.6-1.7-1.41.31.3-1.21.11.5
Bone: elastic work2.12.74.01.5-1.5-1.31.8-1.81.8-2.0-1.91.6-1.8-1.4-1.61.51.5-1.51.41.9
Bone: endosteal estimation0.40.91.9-1.21.40.9-1.21.0-1.31.21.2-0.81.20.60.8-0.6-0.60.6-0.5-0.3
Bone: endosteal perimeter0.10.20.6-0.30.50.4-0.40.3-0.50.60.6-0.40.8-0.20.3-0.2-0.20.3-0.20.5
Epididymis fat weight4.610.713.93.5-3.3-3.33.5-3.42.9-3.1-3.23.4-3.7-3.0-3.53.33.3-3.33.22.7
Delta time in closed arm before/after self-admin3.13.04.72.2-2.1-1.52.0-1.71.4-1.5-1.41.8-1.8-1.5-1.91.71.8-1.91.90.8
Delta time in open arm before/after self-admin2.62.57.5-1.01.10.4-1.41.4-1.11.12.2-1.21.82.11.6-1.7-1.71.5-1.3-2.7
Diff in mean of infusions in LGA sessions1.92.13.70.8-0.8-1.01.1-1.41.7-1.3-1.71.4-1.6-1.6-1.41.71.6-1.51.41.9
Delay discount exponential model param3.63.76.12.2-2.1-2.22.1-1.82.4-2.1-0.72.2-1.2-1.1-2.01.91.9-2.32.51.0
Extinction: sum of active levers before priming0.10.10.30.5-0.4-0.20.3-0.30.40.1-0.20.4-0.1-0.2-0.30.40.4-0.50.50.5
Active lever presses in extinction session 61.81.73.0-1.61.71.5-1.71.2-0.91.31.3-1.31.51.31.3-1.2-1.11.2-1.1-0.7
Bone: final force1.22.02.9-1.61.61.4-1.71.3-1.31.31.4-1.41.51.41.5-1.4-1.41.4-1.3-1.1
Bone: final moment0.61.01.5-1.21.21.0-1.21.0-0.90.91.0-1.01.11.01.0-0.9-0.90.9-0.8-0.6
Food consumed during 24 hour testing period0.91.02.50.8-0.7-1.60.7-0.81.3-1.3-1.11.2-1.3-0.3-1.01.01.0-1.01.00.0
Glucose7.511.214.53.5-3.5-3.63.6-3.43.7-3.8-2.83.4-3.1-3.4-3.33.33.3-3.33.22.9
Heart weight1.92.76.71.9-1.8-2.61.5-1.52.5-2.3-0.71.8-1.3-1.1-1.51.21.2-1.31.40.3
Delay discount hyperbolic model param3.23.45.42.1-2.0-2.12.0-1.72.3-2.0-0.72.1-1.1-1.0-1.91.81.8-2.12.31.0
Intermittent access intake day 1-15 change0.20.20.50.4-0.4-0.70.3-0.40.5-0.20.00.4-0.30.6-0.40.10.2-0.30.3-0.7
Intermittent access intake escalation0.10.10.60.0-0.1-0.5-0.0-0.10.3-0.00.10.2-0.20.8-0.20.00.0-0.10.1-0.7
Intermittent access intake escalation 20.10.10.30.5-0.3-0.50.3-0.20.5-0.40.10.2-0.10.3-0.1-0.1-0.1-0.00.1-0.4
Intermitt. access day 1 inactive lever presses0.10.10.8-0.10.2-0.1-0.50.10.1-0.10.70.20.40.9-0.10.10.1-0.30.5-0.5
Intermitt. access day 15 inactive lever presses0.10.20.3-0.20.4-0.2-0.3-0.40.5-0.6-0.40.3-0.4-0.1-0.40.40.5-0.40.40.5
Intermitt. access escalation Index1.00.91.81.2-1.0-1.20.9-0.91.0-0.9-0.31.2-0.6-0.5-1.01.01.0-1.21.3-0.2
Intermittent access day 1 total infusions0.20.22.1-0.70.50.7-0.30.2-0.30.1-0.2-0.20.10.1-0.20.30.4-0.30.31.5
Intermittent access day 15 total infusions0.20.21.1-0.80.60.4-0.3-0.0-0.20.1-0.3-0.0-0.20.4-0.30.40.5-0.30.31.0
Intermittent access terminal intake (last 3 days)0.10.10.8-0.50.40.5-0.3-0.0-0.0-0.1-0.2-0.1-0.10.4-0.10.10.1-0.00.00.9
Intermittent access total infusions0.40.42.6-0.20.00.30.2-0.50.2-0.4-0.80.4-0.6-0.0-0.70.80.9-0.70.71.6
Intermittent access day 1 locomotion0.40.42.3-0.20.00.20.4-0.20.2-0.3-0.60.4-0.5-0.4-0.70.90.9-0.80.91.5
Intermittent access day 15 total locomotion2.62.84.41.2-1.2-1.71.4-1.62.0-2.1-1.21.8-1.4-0.8-1.91.91.9-2.02.11.7
Intermittent access total locomotion1.72.04.50.9-1.1-0.91.3-1.11.4-1.6-1.21.3-1.2-0.8-1.61.61.7-1.61.72.1
Intermittent access standard deviation0.10.10.70.4-0.7-0.00.8-0.0-0.30.20.20.20.10.5-0.20.10.1-0.30.40.1
Left kidney weight0.20.51.30.30.1-1.10.5-0.51.1-1.0-0.00.8-0.90.0-0.60.60.6-0.70.81.1
Right kidney weight0.10.41.6-0.00.1-1.00.0-0.11.2-1.30.70.5-0.40.7-0.30.10.1-0.30.50.6
Cocaine induced anxiety0.20.20.60.6-0.6-0.50.4-0.20.10.1-0.10.5-0.3-0.3-0.50.60.6-0.70.8-0.0
Post-drug Anxiety0.80.93.0-0.20.30.2-1.01.0-0.20.41.7-0.51.31.70.8-0.8-0.80.4-0.1-1.7
Baseline Anxiety1.21.32.8-0.70.90.7-1.31.0-0.30.31.5-1.01.31.71.2-1.4-1.41.2-1.1-1.3
Tail length0.10.41.40.2-0.1-0.50.6-0.70.6-0.7-0.80.5-0.9-0.6-0.60.60.6-0.50.41.2
Length with tail0.51.94.21.5-1.5-1.91.4-1.42.0-1.9-0.71.5-1.4-0.7-1.31.11.1-1.21.20.7
Length without tail0.41.02.61.2-1.4-1.51.0-0.71.6-1.3-0.01.1-0.7-0.1-0.90.70.7-0.91.0-0.0
Times rat made contact with spout0.30.30.7-0.40.7-0.6-0.2-0.50.8-0.8-0.80.4-0.5-0.7-0.30.50.5-0.30.10.6
Lifetime Intake0.70.85.3-0.0-0.10.30.5-0.70.3-0.5-1.30.5-0.9-0.6-0.91.11.1-0.90.82.3
Liver weight, left0.20.31.20.1-0.0-0.00.50.10.4-0.70.40.4-0.40.6-0.40.60.7-0.81.10.7
Liver weight, right0.71.12.3-1.31.31.4-1.11.3-1.51.50.6-1.11.00.70.8-0.8-0.70.8-0.70.0
Locomotor activity0.40.62.80.10.4-0.1-0.70.5-0.30.60.4-0.60.90.30.8-0.9-0.90.9-1.0-1.7
Locomotor testing distance0.10.21.10.20.1-0.1-0.30.30.20.20.3-0.30.60.30.4-0.5-0.50.5-0.5-1.0
Locomotor testing rearing0.61.01.9-1.11.20.9-1.21.0-0.50.71.1-1.01.40.71.0-1.0-1.01.0-1.1-0.4
Locomotion in novel chamber0.40.51.90.4-0.00.20.3-0.3-0.60.6-1.40.3-0.8-1.2-0.60.80.8-0.50.31.1
Locomotion in novel chamber post-restriction0.20.31.80.0-0.1-0.4-0.30.20.00.10.7-0.20.50.50.3-0.6-0.60.5-0.5-1.3
Fecal boli incidents, locomotor time 10.50.53.50.3-0.4-0.20.9-0.50.1-0.6-0.80.3-0.5-1.0-0.60.60.6-0.50.41.9
Change in fecal boli incidents, locomotor task0.20.20.50.4-0.20.10.4-0.4-0.2-0.1-0.70.4-0.5-0.4-0.60.70.7-0.60.60.2
Time >=10cm from walls, locomotor time 10.90.91.70.3-0.3-0.60.8-0.90.7-0.9-1.30.9-1.1-1.1-1.01.11.1-1.00.81.1
Bouts of movement, locomotor time 10.91.03.3-1.81.81.2-1.60.8-0.91.0-0.1-1.00.50.20.8-0.6-0.60.9-1.10.3
Total resting periods, locomotor time 10.70.82.7-1.61.61.2-1.30.7-0.90.9-0.2-0.80.2-0.10.6-0.5-0.50.8-1.00.2
Rest time, locomotor task time 10.10.10.4-0.20.3-0.6-0.2-0.40.4-0.4-0.50.4-0.4-0.3-0.40.40.4-0.20.2-0.1
Distance moved, locomotor task time 10.70.83.00.4-0.30.1-0.20.7-0.10.11.7-0.51.21.30.8-1.0-1.00.5-0.3-1.7
Vertical activity count, locomotor time 10.70.85.41.1-1.1-0.30.50.10.6-0.71.10.00.71.10.5-0.7-0.70.20.1-2.3
Time >=10cm from walls, locomotor time 23.84.06.72.4-2.6-2.22.4-2.12.6-2.5-1.02.2-1.5-1.5-1.91.71.7-2.02.10.6
Bouts of movement, locomotor time 20.50.61.7-0.80.80.8-1.30.6-0.60.70.2-0.60.31.10.6-0.6-0.60.6-0.7-1.1
Total resting periods, locomotor time 20.30.31.2-0.50.50.5-1.10.3-0.30.40.0-0.30.00.90.3-0.3-0.30.4-0.4-1.0
Rest time, locomotor task time 21.41.63.41.2-0.9-1.60.8-1.41.2-1.2-1.91.2-1.7-1.5-1.31.21.2-1.00.71.0
Distance moved, locomotor task time 21.41.68.5-0.20.10.4-0.60.9-0.20.22.2-0.81.71.71.2-1.4-1.41.0-0.7-2.9
Vertical activity count, locomotor time 21.51.78.4-0.10.10.7-0.51.0-0.30.32.0-0.81.71.91.3-1.4-1.41.0-0.7-2.9
Light reinforcement 11.22.24.8-2.22.11.7-1.71.3-1.61.50.7-1.61.10.41.5-1.3-1.31.6-1.70.2
Light reinforcement 22.83.76.7-1.92.12.2-2.01.8-2.62.30.9-2.21.61.22.1-1.9-1.92.1-2.2-0.9
Bone: marrow area0.40.91.9-1.21.40.9-1.31.0-1.31.21.2-0.81.20.50.8-0.6-0.60.7-0.6-0.4
Bone: maximum diameter2.13.96.8-2.42.62.1-2.42.0-1.82.02.2-2.02.41.52.0-1.7-1.71.7-1.6-0.8
Bone: maximum force0.40.71.1-1.01.00.8-1.00.7-0.40.31.0-0.91.01.01.0-0.9-0.90.9-0.8-0.6
Bone: maximum moment0.10.20.5-0.60.60.4-0.50.40.0-0.10.7-0.40.60.70.5-0.5-0.50.4-0.3-0.2
Mean time between licks in bursts0.20.32.20.10.1-1.0-0.3-0.30.2-0.10.40.60.2-0.4-0.50.40.4-0.40.4-1.5
Mean num. licks in bursts1.92.25.01.3-1.4-1.31.5-1.81.5-1.5-1.91.3-1.6-2.2-1.41.51.4-1.10.81.3
Cd content in liver0.00.00.3-0.10.10.20.00.0-0.20.50.00.10.1-0.2-0.20.30.3-0.30.30.2
Co content in liver0.40.41.40.5-0.7-0.70.2-0.1-0.00.0-0.10.8-0.30.4-0.70.80.8-1.01.2-0.9
Cu content in liver3.34.05.5-2.22.12.4-2.12.2-1.92.21.6-2.32.01.62.2-2.0-2.02.0-2.0-0.7
Fe content in liver1.92.22.9-1.31.41.2-1.51.7-1.31.51.7-1.51.41.41.7-1.5-1.61.5-1.5-1.6
K content in liver0.20.21.1-0.30.40.6-0.50.7-0.40.30.7-0.40.61.00.3-0.3-0.20.00.20.0
Mg content in liver0.91.02.0-1.31.41.3-1.21.2-1.11.00.5-1.00.81.10.8-0.7-0.60.6-0.5-0.1
Mn content in liver0.40.51.00.4-0.3-0.90.4-0.51.0-0.8-0.70.8-0.6-0.1-0.80.70.8-0.80.90.5
Na content in liver0.00.10.30.1-0.10.40.00.10.00.20.3-0.10.10.30.10.00.1-0.10.20.6
Rb content in liver2.12.65.7-1.91.91.1-2.12.2-1.41.41.8-1.41.82.41.3-1.4-1.21.1-0.8-1.0
Se content in liver0.81.03.0-0.60.70.4-1.31.1-1.01.00.8-0.70.91.50.8-0.9-0.90.7-0.6-1.7
Sr content in liver0.70.71.6-0.60.41.1-0.60.7-1.21.30.5-0.90.80.20.9-0.8-0.80.8-0.9-0.0
Zn content in liver2.22.43.4-1.61.71.8-1.81.5-1.81.81.1-1.61.41.31.6-1.5-1.51.5-1.5-1.3
Bone: minimum diameter0.71.32.5-1.41.61.2-1.31.2-0.40.61.5-1.11.51.11.2-1.0-1.01.0-0.90.0
Time in familiar zone, hab. session 10.10.10.40.2-0.3-0.60.1-0.20.6-0.5-0.20.4-0.60.4-0.20.20.2-0.20.3-0.1
Time in novel zone, hab. session 11.01.01.6-0.80.91.2-0.80.8-1.21.10.9-1.11.1-0.01.1-1.1-1.11.2-1.3-0.6
Total zone transitions, hab. session 12.23.05.61.8-1.8-1.81.6-1.71.5-1.7-1.42.0-1.6-0.9-1.92.02.0-2.22.40.2
Total locomotion distance, hab. session 10.20.41.40.2-0.3-0.10.2-0.3-0.20.0-0.50.6-0.3-0.1-0.60.91.0-1.11.2-0.3
Locomotion velocity, hab. session 10.40.62.10.3-0.3-0.10.4-0.3-0.20.1-0.80.7-0.4-0.2-0.81.21.3-1.31.40.1
Time in familiar zone, hab. session 23.43.56.0-2.52.41.7-2.22.2-1.82.20.9-2.01.31.31.8-1.8-1.82.1-2.2-0.8
Time in novel zone, hab. session 23.13.15.12.3-2.2-1.52.0-2.01.4-1.7-0.91.8-1.3-1.5-1.81.81.8-2.02.11.0
Total zone transitions, hab. session 20.20.30.60.3-0.2-0.40.4-0.50.6-0.8-0.60.5-0.4-0.6-0.50.60.6-0.50.50.6
Total locomotion distance, hab. session 20.20.20.9-0.81.00.5-0.60.4-0.40.6-0.4-0.30.2-0.20.10.10.10.0-0.10.3
Locomotion velocity, hab. session 20.10.20.5-0.50.60.2-0.2-0.0-0.20.3-0.70.1-0.1-0.5-0.30.50.5-0.40.30.5
Novel to familiar place preference ratio1.71.73.51.8-1.8-0.91.9-1.81.4-1.6-1.51.0-1.5-1.6-0.90.80.7-0.60.30.7
Novelty place preference2.02.04.02.0-2.0-1.02.0-1.91.4-1.7-1.61.1-1.6-1.7-1.00.90.7-0.70.40.7
Time in novel zone, NPP test1.71.73.51.9-1.8-0.91.9-1.81.3-1.6-1.41.0-1.5-1.8-0.90.70.6-0.60.30.6
Total zone transitions, NPP test0.10.20.8-0.10.2-0.2-0.0-0.10.2-0.40.20.40.20.3-0.40.50.6-0.70.90.6
Total locomotion distance, NPP test0.20.31.1-0.91.00.7-0.70.5-0.70.6-0.1-0.20.40.80.10.20.3-0.30.40.5
Locomotion velocity, NPP test0.30.41.4-1.11.20.8-0.80.6-0.80.60.1-0.40.60.90.20.10.2-0.20.30.4
Intraocular pressure3.34.67.92.4-2.5-2.82.1-2.62.2-2.3-1.72.4-1.7-2.6-2.21.91.9-1.91.70.7
Delta distance traveled before/after self-admin1.11.24.6-1.92.01.5-1.10.6-1.10.6-0.9-0.60.0-1.10.10.50.50.0-0.22.1
Delta ambulatory time before/after self-admin1.11.24.8-1.91.91.6-1.00.7-1.10.6-0.8-0.70.1-1.10.20.40.40.1-0.32.2
Parametrial fat weight1.63.19.01.6-1.9-0.82.3-1.41.0-1.1-2.71.3-1.8-2.2-1.61.61.6-1.41.13.0
Pavlov. Cond. lever latency0.10.20.9-0.10.30.20.0-0.2-0.30.3-0.1-0.30.0-1.00.3-0.3-0.40.6-0.8-0.3
Pavlov. Cond. magazine entry latency0.50.62.1-0.40.20.6-0.60.8-0.20.20.8-0.80.71.50.9-1.1-1.10.9-0.7-0.2
Pavlov. Cond. change in total contacts0.20.21.00.0-0.10.2-0.30.6-0.40.40.6-0.30.61.00.5-0.5-0.50.3-0.2-0.7
Pavlov. Cond. index score0.10.11.30.1-0.30.1-0.10.50.0-0.00.3-0.10.21.10.1-0.2-0.1-0.10.30.2
Pavlov. Cond. latency score0.10.10.80.3-0.6-0.10.20.20.1-0.2-0.00.2-0.10.9-0.10.10.1-0.30.50.3
Pavlov. Cond. lever contacts0.20.22.0-0.1-0.10.4-0.20.6-0.20.10.6-0.10.31.40.2-0.2-0.1-0.20.40.5
Pavlov. Cond. magazine entry number0.30.41.40.4-0.1-0.40.5-0.80.5-0.6-0.50.6-0.5-1.2-0.60.70.7-0.60.50.4
Pavlov. Cond. intertrial magazine entries0.20.20.6-0.60.70.2-0.50.4-0.40.20.7-0.00.60.50.10.20.3-0.30.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.21.4-0.1-0.10.3-0.20.6-0.20.20.4-0.30.31.20.3-0.4-0.30.10.00.2
Pavlov. Cond. response bias0.20.32.0-0.40.20.3-0.50.8-0.20.30.7-0.40.51.40.5-0.5-0.50.3-0.10.1
Pavlov. Cond. lever latency0.70.92.21.2-1.3-1.51.0-1.00.9-0.9-0.71.0-1.0-0.5-0.90.60.5-0.60.5-1.2
Pavlov. Cond. magazine entry latency0.10.10.5-0.40.20.3-0.20.1-0.50.70.2-0.10.2-0.10.00.20.2-0.10.2-0.1
Pavlov. Cond. change in total contacts1.21.73.6-1.21.21.9-1.21.3-1.61.51.6-1.51.60.91.3-1.1-1.11.0-1.00.4
Pavlov. Cond. index score0.40.51.2-0.70.71.1-0.70.7-1.01.10.7-0.70.90.50.6-0.4-0.30.3-0.20.4
Pavlov. Cond. latency score0.40.51.1-0.60.61.1-0.60.8-1.01.00.8-0.70.90.60.6-0.4-0.30.3-0.20.3
Pavlov. Cond. lever contacts0.70.92.4-1.41.51.4-1.11.0-0.90.90.8-0.91.10.50.7-0.4-0.40.5-0.41.0
Pavlov. Cond. magazine entry number0.81.02.31.0-0.9-1.31.0-1.01.4-1.5-0.91.0-1.1-0.8-0.90.80.8-0.80.70.3
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.20.2-0.1-0.20.10.1-0.20.20.0-0.10.10.10.0-0.00.1-0.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.70.71.1-0.70.8-1.11.20.8-0.70.90.50.6-0.4-0.30.3-0.20.3
Pavlov. Cond. response bias1.31.83.5-1.71.91.9-1.51.4-1.41.61.3-1.41.50.81.3-1.0-0.91.0-1.00.5
Time in closed arm before self-admin0.30.41.30.4-0.3-1.20.4-0.51.0-1.0-0.20.7-0.4-0.1-0.50.40.4-0.40.5-0.8
Time in closed arm after self-admin1.11.23.01.1-1.0-1.11.2-1.01.2-1.7-0.91.1-1.2-0.9-1.01.01.0-1.01.10.2
Time in open arm before self-admin0.60.63.7-0.2-0.10.40.3-0.4-0.30.5-1.30.2-0.8-1.3-0.60.70.7-0.40.21.9
Time in open arm after self-admin0.91.03.2-0.60.70.1-1.11.0-0.40.81.8-0.61.41.40.9-1.0-0.90.7-0.5-1.8
Bone: periosteal estimation1.42.84.9-2.02.21.6-2.11.7-1.41.61.9-1.62.01.41.7-1.6-1.51.6-1.4-0.9
Bone: periosteal perimeter0.71.12.2-1.21.31.1-1.21.0-0.60.91.3-1.11.50.61.1-1.0-1.01.0-1.00.3
Bone: post-yield work0.10.20.7-0.50.40.5-0.30.5-0.1-0.00.3-0.40.40.80.5-0.5-0.40.4-0.3-0.5
Progressive ratio test 1 active lever presses0.70.72.7-0.1-0.3-0.10.5-0.70.4-0.6-1.00.6-1.0-0.7-0.91.11.2-1.01.01.7
Progressive ratio test 1 breakpoint0.70.83.00.0-0.4-0.00.5-0.80.4-0.6-1.10.7-1.0-0.8-0.91.21.2-1.01.01.7
Progressive ratio test 1 inactive lever presses0.20.20.8-0.60.40.7-0.2-0.2-0.50.2-0.60.0-0.5-0.0-0.30.50.5-0.40.30.9
Progressive ratio test 2 active lever presses1.31.44.40.3-0.3-0.20.7-1.10.7-0.9-1.41.0-1.3-0.8-1.31.61.6-1.41.42.1
Progressive ratio test 2 breakpoint1.41.64.00.6-0.6-0.40.9-1.20.9-1.0-1.31.1-1.3-0.7-1.41.61.7-1.61.62.0
Progressive ratio test 2 inactive lever presses0.60.71.9-0.0-0.4-0.10.4-0.50.5-0.7-0.60.8-0.6-0.1-1.01.21.3-1.31.41.3
Incentive Sensitization - Responses0.20.20.50.2-0.2-0.20.2-0.60.4-0.4-0.20.5-0.40.1-0.50.60.7-0.60.70.5
Incentive Sensitization - Breakpoint0.20.20.50.3-0.2-0.30.2-0.60.4-0.4-0.30.5-0.50.1-0.50.70.7-0.70.70.5
Sum of active levers in priming session hrs 5-61.61.54.3-1.71.21.9-0.80.9-1.82.1-0.2-1.30.5-0.61.0-0.6-0.71.0-1.21.4
Progressive ratio0.50.63.30.3-0.30.40.7-0.3-0.10.2-1.40.0-0.8-1.4-0.40.40.4-0.2-0.11.8
Food seeking constrained by brief footshock0.20.30.5-0.20.30.5-0.30.3-0.50.70.5-0.60.60.50.6-0.6-0.70.6-0.7-0.3
Seeking ratio, punishment vs. effort0.60.73.4-0.40.5-0.1-0.90.4-0.20.21.5-0.41.11.50.6-0.8-0.80.6-0.4-1.8
Retroperitoneal fat weight3.511.516.04.0-3.7-3.73.9-3.43.3-3.1-3.13.5-3.5-3.7-3.43.23.1-3.13.02.7
Reaction time number correct0.91.42.11.0-1.2-1.50.9-1.21.2-1.4-0.61.4-0.6-1.3-1.31.31.3-1.31.2-0.6
Reaction time mean minus median0.30.41.3-0.50.30.4-0.50.4-0.81.10.2-0.60.6-0.50.7-0.6-0.70.9-1.1-0.7
Reaction time mean minus median AUC0.20.32.20.0-0.3-0.00.3-0.3-0.10.7-1.00.1-0.3-1.5-0.10.30.20.1-0.40.4
Reaction time num false alarms1.31.84.11.4-1.5-0.91.8-1.40.6-0.8-2.01.1-1.8-1.6-1.31.31.3-1.10.91.1
Reaction time num false alarms AUC2.12.95.61.8-1.9-1.22.2-1.80.9-1.1-2.41.5-2.1-2.0-1.71.71.7-1.51.31.5
Reaction time trials correct on left0.91.42.11.0-1.2-1.50.9-1.21.2-1.4-0.61.4-0.6-1.3-1.31.31.3-1.31.2-0.6
Reaction time trials on left1.01.42.21.0-1.2-1.51.0-1.31.2-1.3-0.71.4-0.6-1.4-1.31.31.3-1.31.2-0.6
Reaction time mean0.40.61.51.1-1.2-0.71.0-0.70.30.1-1.10.6-0.9-1.2-0.60.50.5-0.40.20.0
Reaction time mean AUC0.30.41.50.9-0.9-0.40.8-0.5-0.00.5-1.20.4-0.8-1.2-0.50.50.4-0.30.00.1
Median of all reaction times1.01.42.71.7-1.6-1.01.5-1.20.7-0.4-1.61.0-1.5-1.5-1.11.01.0-0.90.70.5
Reaction time omissions0.10.11.2-0.1-0.00.2-0.20.3-0.51.1-0.1-0.20.1-0.30.1-0.1-0.20.3-0.4-0.5
Reaction time false alarm rate0.81.12.91.2-1.2-0.41.5-1.00.3-0.4-1.70.6-1.5-1.1-0.80.80.8-0.70.51.4
Reaction time premature initiation rate3.24.211.2-2.62.41.3-2.52.5-1.01.52.8-1.72.13.41.9-1.8-1.71.5-1.0-1.7
Reaction time premature initiations1.42.05.5-1.91.60.7-1.81.7-0.50.82.1-0.91.62.31.1-1.0-0.90.8-0.4-1.6
Std. dev. reaction times0.20.31.80.5-0.6-0.70.3-0.50.10.6-1.00.4-0.5-1.4-0.30.40.3-0.0-0.3-0.5
Reaction time trials completed1.01.42.21.0-1.2-1.51.0-1.31.2-1.3-0.71.4-0.6-1.4-1.31.31.3-1.31.2-0.6
Reaction time trials AUC1.01.42.11.0-1.2-1.51.0-1.31.2-1.4-0.71.4-0.6-1.4-1.31.31.3-1.21.2-0.6
Run reversals in cocaine runway, females0.60.61.0-0.20.70.9-0.50.7-0.90.90.3-0.90.50.20.9-0.9-0.90.9-1.0-0.8
Run reversals in cocaine runway, males0.10.10.50.3-0.30.30.10.3-0.40.40.1-0.30.20.10.2-0.4-0.40.3-0.3-0.7
Latency to leave start box in cocaine runway1.51.72.6-1.51.61.4-1.21.2-1.11.00.9-1.41.10.81.4-1.4-1.41.6-1.6-0.8
Latency to leave start box in cocaine runway, F1.61.82.9-1.51.51.0-1.31.2-0.70.71.7-1.31.51.21.4-1.5-1.51.5-1.4-1.2
Latency to leave start box in cocaine runway, M0.30.31.90.4-0.30.40.4-0.3-0.1-0.1-1.40.0-0.8-0.9-0.20.40.3-0.1-0.20.8
Std. dev. time between licks in bursts0.10.10.5-0.20.40.1-0.30.3-0.40.30.6-0.20.60.30.2-0.2-0.20.1-0.1-0.7
Total sessions with >9 infusions1.61.82.91.1-1.4-0.71.5-1.41.0-1.1-1.61.2-1.7-0.9-1.41.51.5-1.41.41.6
Short access day 1 total inactive lever presses0.40.53.7-0.60.60.9-0.70.1-0.40.4-0.4-0.0-0.00.3-0.20.70.7-0.60.71.9
Short access day 10 total inactive lever presses0.50.61.4-0.91.10.3-1.20.5-0.20.21.1-0.51.01.00.7-0.6-0.60.5-0.4-1.0
Short access day 1 total infusions2.12.313.30.6-0.70.51.3-1.30.1-0.3-2.20.7-1.6-2.1-1.21.51.5-1.21.03.7
Short access day 10 total infusions0.10.10.7-0.40.00.30.0-0.20.1-0.1-0.40.1-0.20.3-0.20.40.4-0.30.30.8
Short access total infusions0.60.75.6-0.2-0.10.70.4-0.5-0.20.0-1.20.1-0.8-0.8-0.60.70.7-0.50.32.4
Short access day 1 locomotion3.33.56.81.0-1.4-1.01.9-1.81.3-1.2-2.61.7-2.3-1.9-2.02.32.3-1.91.82.5
Short access day 10 total locomotion1.51.73.51.4-1.7-1.61.9-1.21.4-1.6-0.61.4-1.1-0.5-1.31.11.1-1.31.3-0.5
Short access total locomotion1.21.32.10.9-1.2-0.81.5-1.01.0-1.0-1.21.1-1.3-0.6-1.31.21.2-1.21.21.1
One hour access (0.3 mA shock)0.80.92.90.3-0.6-0.20.7-1.10.7-1.0-1.70.6-1.2-0.7-1.01.01.0-0.80.61.5
Compulsive drug intake0.90.92.61.0-1.0-0.71.3-1.30.8-0.7-1.40.7-1.1-1.6-0.70.70.6-0.50.21.1
One hour access (shock baseline)0.10.10.4-0.40.10.3-0.2-0.0-0.1-0.0-0.30.1-0.20.6-0.40.40.5-0.40.50.5
Social response proportion0.80.92.71.5-1.7-0.81.0-0.70.5-0.7-1.20.7-0.5-1.5-0.80.60.5-0.50.3-0.7
Social responses0.30.41.8-0.10.11.4-0.31.0-1.10.9-0.2-0.80.70.10.5-0.4-0.40.4-0.50.2
Social time0.30.41.70.8-0.7-0.10.7-0.50.6-0.3-1.30.2-0.5-0.9-0.50.30.2-0.1-0.10.9
Soleus weight1.44.17.82.7-2.8-1.92.5-2.22.2-2.3-1.51.9-1.8-1.7-1.91.61.6-1.81.71.8
Bone: stiffness1.01.62.7-1.31.31.0-1.51.2-0.90.91.6-1.21.41.41.3-1.3-1.31.2-1.0-1.2
Tibialis anterior weight0.72.24.81.5-1.5-2.21.4-1.62.1-1.7-1.51.7-1.4-1.3-1.61.21.2-1.21.10.2
Time to tail flick, vehicle, before self-admin3.43.55.6-1.61.41.9-1.51.9-1.71.81.4-2.01.61.32.1-2.1-2.22.3-2.4-2.1
Time to tail flick, vehicle, after self-admin0.20.20.5-0.4-0.10.4-0.00.5-0.70.70.5-0.50.50.70.5-0.5-0.50.4-0.4-0.2
Time to tail flick, test, before self-admin0.20.20.70.4-0.5-0.30.5-0.50.8-0.8-0.20.3-0.1-0.6-0.30.40.4-0.40.40.4
Time to tail flick, test, after self-admin0.50.51.9-0.70.91.4-0.50.8-0.70.20.3-0.90.70.00.7-0.6-0.60.7-0.70.3
Delta time to tail flick, vehicle, before/after SA0.70.71.50.5-0.6-0.90.6-0.70.8-0.8-0.30.9-0.5-0.3-1.00.91.0-1.01.11.2
Delta time to tail flick, test, before/after SA0.20.10.50.20.10.7-0.10.6-0.50.30.1-0.50.10.10.3-0.5-0.40.4-0.50.2
Tibia length0.61.74.01.2-1.2-2.01.0-1.21.4-0.9-1.51.5-1.6-1.5-1.41.31.3-1.11.00.4
Ambulatory time before self-admin0.10.10.30.3-0.30.30.1-0.2-0.00.4-0.1-0.3-0.1-0.00.4-0.4-0.40.4-0.60.0
Ambulatory time after self-admin0.50.54.2-0.60.91.2-0.30.1-0.40.2-0.7-0.5-0.1-0.80.30.10.10.2-0.42.1
Bone: tissue strength0.00.00.20.2-0.2-0.10.3-0.20.2-0.0-0.20.1-0.3-0.4-0.10.10.1-0.10.00.1
Total heroin consumption0.50.61.70.7-0.60.11.0-1.2-0.30.5-1.30.3-0.8-1.3-0.40.50.5-0.30.11.2
Bone: trabecular number0.30.42.0-0.71.00.1-1.00.7-0.20.20.2-0.30.41.40.4-0.4-0.30.3-0.1-1.1
Bone: trabecular spacing0.10.20.6-0.10.20.1-0.20.4-0.30.50.8-0.40.7-0.10.3-0.5-0.50.5-0.60.2
Bone: trabecular thickness0.40.52.0-0.80.80.3-0.80.9-0.20.30.2-0.40.41.40.6-0.5-0.50.5-0.3-1.2
Bone: trabecular tissue density0.10.21.50.5-0.5-0.50.1-0.3-0.10.00.40.00.2-0.10.1-0.3-0.40.3-0.3-1.2
Water consumed over 24 hours0.10.20.7-0.70.8-0.2-0.70.30.3-0.1-0.2-0.1-0.10.40.3-0.1-0.20.3-0.3-0.4
Number of responses in last shaping day0.50.52.4-1.51.30.8-0.70.7-0.90.8-0.3-0.4-0.0-0.30.00.20.30.1-0.10.9