Best TWAS P=1.596035e-07 · Best GWAS P=7.456127e-07 conditioned to 0.03842199
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Otub1 | alternative polyA | ENSRNOT00000114563 | 0.16 | 0.08 | enet | 97 | 0.09 | 1.9e-10 | -4.2 | 5.2 | 1.6e-07 | -0.64 | 0.48 | 0.5 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.