Hub : Genes

Spats2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Spats2 0.32 0.19 5.0e-06 0.12 0.19 0.14 0.15 7.7e-04 3.2e-05 2.9e-04 1.9e-04
2 IC gene expression Spats2 0.33 0.24 2.8e-10 0.18 0.19 0.21 0.19 3.5e-08 1.9e-08 4.7e-09 2.0e-08
3 BLA gene expression Spats2 0.24 0.16 2.3e-11 0.19 0.19 0.17 0.19 4.0e-10 1.6e-10 2.4e-09 1.7e-10
4 PL alternative TSS XM_039078933.2 0.02 0.03 8.1e-03 0.01 0.02 0.01 0.01 1.7e-02 6.5e-03 7.5e-03 8.0e-03
5 IL gene expression Spats2 0.14 0.11 2.0e-03 0.07 0.11 0.08 0.08 1.0e-02 1.2e-03 6.9e-03 5.0e-03
6 Brain gene expression Spats2 0.14 0.09 5.0e-16 0.17 0.17 0.15 0.17 3.0e-15 4.2e-16 5.5e-14 2.0e-15
7 NAcc gene expression Spats2 0.16 0.09 0.0e+00 0.22 0.22 0.22 0.22 2.1e-32 3.5e-33 4.5e-33 1.1e-32
8 RMTg alternative TSS XM_063263385.1 0.12 0.11 9.2e-03 0.05 0.05 0.02 -0.01 1.7e-02 2.4e-02 8.1e-02 7.0e-01
9 RMTg gene expression Spats2 0.22 0.16 1.2e-04 0.08 0.1 0.04 0.07 3.9e-03 1.5e-03 2.8e-02 5.8e-03
10 LHb gene expression Spats2 0.24 0.14 9.3e-06 0.1 0.16 0.09 0.11 2.0e-03 1.3e-04 3.1e-03 1.7e-03
11 RMTg isoform ratio XM_063263385.1 0.14 0.12 4.2e-03 0.02 0.06 0.05 0.02 1.1e-01 1.5e-02 1.7e-02 9.5e-02
12 RMTg alternative TSS XM_063263385.1 0.13 0.12 4.7e-03 0.05 0.05 0.06 0.03 1.6e-02 2.1e-02 1.4e-02 6.4e-02
13 Liver gene expression Spats2 0.13 0.11 6.6e-12 0.09 0.09 0.09 0.09 6.5e-10 2.2e-10 2.4e-10 3.3e-10
14 Adipose gene expression Spats2 0.1 0.1 1.5e-09 0.07 0.08 0.07 0.07 1.5e-08 8.5e-09 1.1e-08 9.9e-09
15 pVTA gene expression Spats2 0.26 0.19 1.1e-16 0.2 0.2 0.2 0.2 2.9e-16 7.8e-16 3.2e-16 2.3e-16
16 PL gene expression Spats2 0.28 0.15 0.0e+00 0.26 0.26 0.25 0.26 1.7e-28 4.7e-28 2.5e-27 1.6e-28
17 Adipose intron excision ratio chr7_132201302_132202554 0.04 0.04 3.2e-04 0.03 0.03 0.03 0.03 5.4e-04 6.5e-04 6.4e-04 6.1e-04
18 PL isoform ratio XM_039078932.2 0.05 0.05 5.8e-06 0.05 0.05 0.05 0.05 8.5e-06 2.4e-06 2.1e-06 1.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density9.516.317.8-4.2-3.6-4.24.2-4.2-4.1-4.2-4.2-4.2-4.2-4.2-4.24.24.2-4.1-4.0-3.1-3.4
Area under the delay curve0.91.01.8-1.0-1.1-0.90.9-0.9-0.9-0.9-1.3-0.9-0.9-0.9-1.20.90.9-1.0-0.8-1.2-0.9
BMI with tail7.124.326.2-5.1-5.1-5.05.0-4.9-4.9-4.9-5.0-4.9-4.9-4.9-5.04.94.9-5.1-4.6-5.0-4.6
BMI without tail1.75.36.5-2.4-2.4-2.32.3-2.3-2.2-2.3-2.2-2.3-2.3-2.3-2.22.32.3-2.5-2.0-2.4-2.2
Body weight6.930.434.1-5.7-5.6-5.65.5-5.5-5.5-5.5-5.6-5.6-5.5-5.5-5.55.45.5-5.8-5.1-5.2-5.5
Weight adjusted by age2.03.13.7-1.8-1.4-1.81.8-1.8-1.8-1.8-1.8-1.9-1.9-1.9-1.71.91.9-1.9-1.9-1.1-1.0
Bone surface11.420.822.2-4.7-4.4-4.74.7-4.7-4.7-4.7-4.6-4.7-4.7-4.7-4.64.74.7-4.6-4.5-4.0-3.7
Bone volume8.916.017.1-4.1-3.8-4.14.1-4.1-4.1-4.1-4.1-4.1-4.1-4.1-4.14.14.1-4.0-3.9-3.4-3.6
Breakpoint value in progressive ratio session1.31.62.2-1.3-1.3-1.31.3-1.3-1.4-1.3-0.9-1.3-1.3-1.3-0.91.31.3-1.2-1.5-1.1-1.0
Number of licking bursts0.60.92.80.81.50.9-0.90.80.90.80.90.80.80.80.9-0.8-0.70.40.81.71.2
Context. condit. distance diff. score0.20.30.4-0.5-0.3-0.50.5-0.5-0.5-0.5-0.6-0.5-0.5-0.5-0.60.50.5-0.6-0.6-0.2-0.5
Locomotion velocity, session 11.31.44.11.11.51.1-1.11.01.11.01.21.01.01.01.1-0.9-1.01.00.91.52.0
Locomotion distance, session 12.63.34.01.91.91.8-1.81.81.81.81.71.81.81.81.7-1.8-1.82.01.61.62.0
Locomotion velocity, session 20.20.20.30.50.40.5-0.50.50.50.50.50.50.50.50.5-0.5-0.50.50.50.30.5
Locomotion distance, session 22.23.13.91.81.71.8-1.81.81.81.81.71.81.81.81.7-1.7-1.81.91.61.42.0
Locomotion velocity, session 34.45.06.22.32.52.3-2.32.22.32.22.22.22.22.22.2-2.2-2.22.12.12.32.3
Locomotion distance, session 34.75.16.02.42.12.4-2.32.32.32.42.22.42.42.42.2-2.4-2.42.52.31.61.6
Stereotopy head waving bouts, day 30.91.11.5-1.1-0.6-1.11.1-1.1-1.1-1.1-0.9-1.2-1.2-1.2-1.01.21.2-1.2-1.0-0.4-0.2
Stereotopy head waving duration, day 30.50.60.9-0.8-0.4-0.80.8-0.9-0.8-0.9-0.7-0.9-0.9-0.9-0.70.90.9-0.9-0.8-0.20.0
Locomotion velocity, session 70.60.72.40.71.30.7-0.70.60.70.60.80.60.60.60.7-0.5-0.50.60.61.61.5
Locomotion distance, session 72.22.84.61.62.01.6-1.61.61.61.61.71.51.51.51.7-1.5-1.51.51.62.22.0
Stereotopy head waving bouts, day 71.21.31.9-1.2-1.0-1.21.2-1.2-1.1-1.2-1.1-1.2-1.2-1.2-1.21.21.2-1.4-1.1-1.0-0.8
Stereotopy head waving duration, day 71.11.41.6-1.2-1.1-1.21.2-1.2-1.1-1.2-1.2-1.2-1.2-1.2-1.21.21.2-1.3-1.1-1.2-1.1
Locomotion velocity, session 80.10.11.20.10.60.0-0.10.00.0-0.0-0.00.00.00.0-0.10.00.0-0.2-0.11.10.5
Locomotion distance, session 81.11.61.91.31.41.3-1.31.31.31.31.21.31.31.31.2-1.3-1.31.31.11.31.3
Degree of sensitization distance0.30.30.5-0.6-0.3-0.60.6-0.6-0.6-0.6-0.5-0.6-0.6-0.7-0.50.70.7-0.7-0.60.00.0
Degree of sensitization stereotypy0.20.20.6-0.4-0.5-0.40.3-0.3-0.3-0.3-0.5-0.4-0.3-0.4-0.40.30.3-0.5-0.2-0.8-0.7
Conditioned locomotion0.00.00.2-0.00.3-0.00.1-0.1-0.1-0.10.0-0.1-0.1-0.1-0.00.10.1-0.1-0.20.40.4
Cocaine response after cond. corrected0.00.00.00.10.10.1-0.10.10.10.1-0.00.10.10.1-0.0-0.1-0.10.10.1-0.10.0
Cocaine response after cond. not corrected0.50.60.70.80.70.8-0.80.80.80.80.70.80.80.80.7-0.8-0.80.90.90.50.4
Cocaine response before conditioning3.54.24.72.12.02.1-2.12.12.12.12.12.12.12.12.1-2.1-2.12.22.01.91.5
Saline control response0.00.00.4-0.10.2-0.10.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.20.20.2-0.1-0.20.60.1
Bone: connectivity density6.39.911.0-3.3-2.7-3.23.3-3.3-3.2-3.3-3.2-3.3-3.3-3.3-3.33.33.3-3.2-3.2-2.3-2.2
Bone: cortical apparent density0.10.20.30.50.50.4-0.40.40.40.40.40.50.40.50.4-0.5-0.50.60.40.50.3
Bone: cortical area10.315.818.6-4.2-3.6-4.14.1-4.1-4.1-4.1-3.9-4.2-4.1-4.2-3.94.14.2-4.3-4.0-3.0-2.9
Bone: cortical porosity0.50.51.40.80.40.7-0.70.70.70.70.60.80.80.80.6-0.8-0.81.20.70.5-0.1
Bone: cortical porosity0.70.81.90.90.60.9-0.90.90.80.90.81.00.91.00.9-1.0-1.01.40.90.60.1
Bone: cortical thickness3.65.98.6-2.6-1.9-2.52.5-2.6-2.5-2.6-2.4-2.6-2.6-2.6-2.42.62.6-2.9-2.4-1.2-1.7
Bone: cortical thickness0.10.10.2-0.3-0.1-0.20.2-0.2-0.2-0.2-0.1-0.3-0.3-0.3-0.10.30.3-0.4-0.10.20.3
Bone: cortical tissue density0.20.30.50.60.60.5-0.50.50.50.50.50.60.50.60.4-0.5-0.60.70.50.60.4
Condit. Reinf. active minus inactive responses0.10.10.30.20.40.2-0.20.20.20.20.40.20.20.20.3-0.2-0.20.30.20.50.4
Condit. Reinf. active-inactive response ratio0.20.30.4-0.5-0.4-0.50.6-0.6-0.6-0.6-0.5-0.5-0.6-0.6-0.50.60.6-0.3-0.6-0.2-0.2
Condit. Reinf. active responses0.60.81.00.90.90.9-0.90.90.90.91.00.90.90.91.0-0.8-0.80.80.80.90.9
Condit. Reinf. inactive responses2.93.53.81.91.81.9-2.01.92.01.91.91.91.91.91.9-1.9-1.91.71.91.51.6
Incentive salience index mean0.00.00.0-0.10.1-0.10.1-0.1-0.1-0.10.0-0.1-0.1-0.1-0.00.10.1-0.2-0.10.20.1
Condit. Reinf. lever presses0.10.20.4-0.4-0.5-0.40.4-0.4-0.4-0.3-0.4-0.4-0.3-0.3-0.40.30.3-0.5-0.3-0.6-0.7
Condit. Reinf. active minus inactive responses0.00.10.70.0-0.20.0-0.00.00.00.1-0.00.10.10.1-0.0-0.1-0.10.20.2-0.4-0.9
Condit. Reinf. active-inactive response ratio0.20.30.50.40.00.5-0.50.50.50.50.30.50.50.60.4-0.6-0.60.60.7-0.3-0.7
Condit. Reinf. active responses0.10.20.40.40.20.4-0.40.40.40.50.50.50.50.50.5-0.5-0.50.70.6-0.0-0.3
Condit. Reinf. inactive responses0.60.70.90.90.90.9-0.80.80.80.80.90.80.80.80.9-0.8-0.80.90.80.70.8
Condit. Reinf. lever presses0.00.00.1-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.10.0-0.00.1-0.3
Condit. Reinf. lever reinforcers received0.40.61.00.80.60.8-0.70.80.70.80.80.80.80.80.8-0.8-0.81.00.90.40.1
Conditioned reinforcement - actives1.01.62.71.31.01.3-1.41.41.41.41.31.41.41.41.3-1.4-1.41.21.70.50.6
Conditioned reinforcement - inactives4.36.27.22.52.52.6-2.62.62.62.62.42.52.52.52.4-2.5-2.52.32.72.22.3
Conditioned locomotion0.30.40.90.50.50.6-0.60.50.50.50.90.50.50.50.9-0.5-0.50.50.60.40.7
Patch foraging indifference point 0 sec3.15.712.72.23.12.2-2.22.12.22.12.52.12.12.12.4-2.0-2.02.02.03.63.4
Patch foraging indifference point AUC0.81.21.31.11.11.1-1.11.11.11.11.11.11.11.11.1-1.1-1.11.01.11.00.8
Delay disc. indifference point, 0s delay1.31.41.9-1.2-1.4-1.21.2-1.2-1.2-1.2-1.0-1.2-1.2-1.2-1.01.21.2-1.2-1.1-1.4-1.4
Delay disc. indifference point, 16s delay0.80.91.7-0.9-1.2-0.90.9-0.9-0.9-0.9-1.0-0.9-0.9-0.9-0.90.90.9-1.0-0.8-1.3-0.9
Delay disc. indifference point, 2s delay1.61.73.3-1.3-1.3-1.31.3-1.3-1.3-1.3-1.8-1.2-1.2-1.2-1.71.21.2-1.2-1.2-1.3-1.3
Delay disc. indifference point, 24s delay0.91.01.5-1.0-1.0-1.01.0-1.0-1.0-1.0-1.1-1.0-1.0-1.0-1.01.01.1-1.2-1.1-0.8-0.5
Delay disc. indifference point, 4s delay0.60.61.7-0.7-1.1-0.70.7-0.7-0.7-0.7-0.9-0.6-0.6-0.6-0.80.60.6-0.6-0.6-1.3-1.1
Delay disc. indifference point, 8s delay1.82.12.8-1.5-1.5-1.51.4-1.5-1.4-1.5-1.6-1.5-1.5-1.5-1.51.51.5-1.7-1.4-1.4-1.1
Indifference point function ln k3.35.76.3-2.4-2.5-2.42.4-2.4-2.4-2.4-2.4-2.4-2.4-2.3-2.42.32.3-2.3-2.3-2.4-2.5
Indifference point function log k3.35.76.3-2.4-2.5-2.42.4-2.4-2.4-2.4-2.4-2.4-2.4-2.3-2.42.32.3-2.3-2.3-2.4-2.5
Patch foraging total patch changes 0 sec2.95.512.22.23.02.2-2.22.12.22.12.42.12.12.02.3-2.0-2.02.02.03.53.2
Patch foraging total patch changes 12 sec3.54.58.82.02.52.1-2.12.02.12.02.21.91.91.92.2-1.9-1.81.71.82.63.0
Patch foraging total patch changes 18 sec4.56.911.32.53.12.6-2.62.52.52.52.82.52.52.42.7-2.4-2.42.52.33.42.9
Patch foraging total patch changes 24 sec2.44.17.81.92.52.0-1.91.91.91.92.21.81.81.82.1-1.8-1.71.71.82.82.5
Patch foraging total patch changes 6 sec3.95.911.82.33.12.3-2.32.22.32.22.52.12.12.12.4-2.1-2.02.12.13.43.4
Patch foraging time to switch 0 sec1.83.74.02.01.92.0-1.91.91.91.92.01.91.91.92.0-1.9-1.91.91.71.81.8
Patch foraging water rate 0 sec2.65.45.9-2.4-2.4-2.42.3-2.3-2.3-2.3-2.2-2.3-2.3-2.3-2.22.32.3-2.4-2.1-2.4-2.2
Patch foraging water rate 12 sec2.55.35.8-2.4-2.4-2.42.4-2.4-2.4-2.3-2.2-2.4-2.3-2.4-2.22.32.3-2.2-2.3-2.4-1.8
Patch foraging water rate 18 sec0.30.41.1-0.7-0.8-0.70.6-0.6-0.6-0.6-0.7-0.6-0.6-0.6-0.70.60.6-0.6-0.5-1.0-0.5
Patch foraging water rate 24 sec3.75.37.2-2.3-2.5-2.32.3-2.2-2.2-2.2-2.5-2.2-2.2-2.2-2.52.12.1-2.1-2.0-2.6-2.7
Patch foraging water rate 6 sec4.76.89.0-2.6-2.8-2.62.6-2.6-2.6-2.6-2.7-2.6-2.5-2.5-2.62.52.5-2.4-2.3-3.0-2.9
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.4-0.4-0.40.4-0.4-0.4-0.4-0.2-0.4-0.3-0.4-0.20.30.3-0.4-0.2-0.4-0.5
Distance traveled before self-admin1.11.54.21.11.71.1-1.11.11.11.01.11.01.01.01.3-1.0-1.01.01.02.01.6
Distance traveled after self-admin0.50.72.60.71.20.6-0.60.60.60.61.10.60.60.60.9-0.5-0.50.50.51.61.2
Extensor digitorum longus weight4.316.820.3-4.1-4.5-4.14.0-4.0-4.0-4.0-4.2-4.0-3.9-3.9-4.03.93.9-4.3-3.8-4.5-4.5
Bone: elastic displacement4.35.07.22.32.42.2-2.22.22.22.22.22.22.22.22.1-2.1-2.22.31.92.52.7
Bone: elastic work0.00.10.2-0.1-0.1-0.20.2-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.30.20.20.1-0.40.10.2
Bone: endosteal estimation8.418.420.1-4.4-4.5-4.44.4-4.4-4.4-4.3-4.2-4.3-4.3-4.3-4.24.34.3-4.1-4.2-4.4-3.6
Bone: endosteal perimeter7.315.517.3-4.0-4.2-4.04.0-4.0-4.0-4.0-3.8-4.0-3.9-4.0-3.83.93.9-4.0-3.8-4.1-3.5
Epididymis fat weight0.82.73.2-1.7-1.4-1.71.7-1.7-1.7-1.7-1.6-1.8-1.8-1.8-1.61.81.8-1.7-1.7-1.2-0.9
Delta time in closed arm before/after self-admin0.10.10.80.1-0.10.1-0.10.10.10.10.90.10.10.10.7-0.1-0.10.10.1-0.1-0.0
Delta time in open arm before/after self-admin1.11.01.51.11.21.1-1.11.11.11.00.31.11.11.10.6-1.1-1.11.01.01.21.0
Diff in mean of infusions in LGA sessions1.11.31.6-1.2-1.3-1.21.2-1.2-1.2-1.2-1.1-1.2-1.2-1.2-1.11.21.2-1.0-1.2-1.2-0.7
Delay discount exponential model param0.80.91.80.91.10.9-0.90.90.90.91.40.90.80.91.2-0.8-0.81.00.81.20.9
Extinction: sum of active levers before priming1.92.12.7-1.4-1.5-1.51.5-1.4-1.5-1.5-1.6-1.4-1.4-1.4-1.41.41.4-1.2-1.4-1.4-1.4
Active lever presses in extinction session 61.01.01.3-1.0-0.6-1.01.1-1.1-1.1-1.1-0.9-1.1-1.1-1.1-0.91.11.1-1.0-1.1-0.3-0.3
Bone: final force11.919.020.4-4.4-4.5-4.44.4-4.4-4.4-4.4-4.4-4.4-4.4-4.4-4.44.34.3-4.3-4.3-4.1-4.1
Bone: final moment13.020.822.6-4.6-4.8-4.64.6-4.6-4.6-4.6-4.6-4.6-4.6-4.6-4.64.54.5-4.4-4.5-4.4-4.4
Food consumed during 24 hour testing period1.52.02.3-1.5-1.1-1.51.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.51.51.5-1.4-1.4-0.8-1.4
Glucose0.10.21.1-0.30.2-0.20.2-0.3-0.2-0.3-0.1-0.3-0.3-0.3-0.20.40.4-0.6-0.40.51.0
Heart weight0.10.20.4-0.3-0.6-0.30.3-0.3-0.3-0.3-0.6-0.3-0.3-0.3-0.50.30.3-0.5-0.3-0.7-0.5
Delay discount hyperbolic model param0.80.91.80.91.10.9-0.90.90.90.91.30.90.90.91.2-0.8-0.81.00.81.20.9
Intermittent access intake day 1-15 change0.10.10.40.3-0.20.3-0.30.30.30.40.10.40.40.40.2-0.4-0.40.40.4-0.4-0.6
Intermittent access intake escalation0.10.11.1-0.0-0.50.0-0.00.10.10.1-0.10.10.10.1-0.0-0.2-0.10.10.1-0.8-1.0
Intermittent access intake escalation 20.20.20.30.40.00.4-0.40.40.40.50.30.50.50.50.4-0.5-0.50.40.6-0.3-0.6
Intermitt. access day 1 inactive lever presses0.20.71.30.90.50.9-0.90.90.90.90.60.90.91.00.6-1.0-1.01.10.80.20.3
Intermitt. access day 15 inactive lever presses0.61.11.71.10.41.1-1.11.21.11.21.01.21.21.21.1-1.2-1.21.21.3-0.20.0
Intermitt. access escalation Index0.40.50.9-0.7-0.2-0.70.7-0.7-0.7-0.8-1.0-0.7-0.8-0.7-1.00.80.8-0.7-0.80.10.0
Intermittent access day 1 total infusions0.91.52.01.31.41.3-1.31.31.31.21.01.21.21.20.9-1.2-1.21.01.21.41.4
Intermittent access day 15 total infusions0.81.21.61.10.91.2-1.21.21.21.21.11.21.21.21.0-1.2-1.21.01.20.70.6
Intermittent access terminal intake (last 3 days)1.31.72.11.31.11.4-1.41.41.41.41.31.41.41.41.3-1.4-1.41.31.40.80.7
Intermittent access total infusions2.02.32.91.61.41.7-1.71.61.71.71.31.61.61.61.4-1.6-1.61.31.61.21.1
Intermittent access day 1 locomotion0.20.31.10.50.70.5-0.50.40.40.40.30.40.40.40.4-0.3-0.30.30.30.91.1
Intermittent access day 15 total locomotion0.20.40.60.60.70.6-0.70.60.60.60.60.60.60.60.6-0.6-0.60.50.50.70.8
Intermittent access total locomotion1.72.02.71.41.61.4-1.41.41.41.41.41.41.41.31.5-1.3-1.31.21.31.61.6
Intermittent access standard deviation0.20.50.60.70.30.7-0.70.80.80.80.60.80.80.80.7-0.8-0.80.70.70.00.0
Left kidney weight1.04.57.0-2.2-2.5-2.12.1-2.0-2.0-2.0-2.1-2.0-2.0-2.0-1.91.92.0-2.3-1.8-2.6-2.6
Right kidney weight4.520.323.4-4.6-4.8-4.54.5-4.5-4.4-4.5-4.5-4.5-4.5-4.5-4.44.44.4-4.7-4.2-4.7-4.4
Cocaine induced anxiety2.63.74.3-2.0-1.8-2.02.0-2.0-2.0-2.0-2.1-2.0-2.0-2.0-2.12.02.0-1.9-1.8-1.7-1.8
Post-drug Anxiety3.43.64.2-2.0-1.8-2.02.0-1.9-1.9-1.9-2.1-1.9-1.9-1.9-1.91.91.9-1.9-1.6-1.9-1.9
Baseline Anxiety0.00.00.1-0.2-0.3-0.20.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.10.10.1-0.2-0.2-0.4-0.4
Tail length0.00.00.3-0.10.2-0.0-0.0-0.00.0-0.00.2-0.1-0.0-0.10.20.00.1-0.30.00.60.1
Length with tail1.66.88.5-2.7-2.4-2.72.6-2.6-2.6-2.6-2.6-2.7-2.6-2.7-2.62.62.7-2.9-2.6-1.9-2.5
Length without tail5.718.520.1-4.4-4.2-4.44.4-4.3-4.3-4.3-4.5-4.3-4.3-4.3-4.44.34.3-4.5-4.2-3.8-4.2
Times rat made contact with spout0.10.10.40.30.60.3-0.30.30.30.30.30.30.30.30.3-0.3-0.30.20.40.50.0
Lifetime Intake2.73.33.91.81.81.9-1.91.92.01.91.61.91.91.91.7-1.9-1.81.51.91.51.5
Liver weight, left10.116.718.4-4.2-4.1-4.14.1-4.1-4.1-4.1-4.1-4.1-4.1-4.1-4.14.04.1-4.3-4.0-3.9-3.9
Liver weight, right3.05.26.0-2.3-2.4-2.32.3-2.3-2.3-2.3-2.3-2.3-2.3-2.3-2.32.22.2-2.2-2.2-2.2-2.4
Locomotor activity1.52.32.81.51.71.5-1.51.51.51.51.51.51.51.51.5-1.5-1.51.51.61.61.3
Locomotor testing distance3.25.86.82.42.62.4-2.42.42.42.42.42.42.42.42.4-2.4-2.32.42.42.52.3
Locomotor testing rearing2.24.35.02.12.22.1-2.12.12.12.12.02.12.12.12.0-2.1-2.12.12.12.21.6
Locomotion in novel chamber2.02.66.8-1.5-2.0-1.51.5-1.4-1.4-1.4-1.7-1.4-1.4-1.4-1.51.31.3-1.4-1.2-2.3-2.6
Locomotion in novel chamber post-restriction0.00.00.40.1-0.20.1-0.10.10.10.1-0.10.10.10.10.0-0.2-0.20.20.2-0.4-0.6
Fecal boli incidents, locomotor time 11.62.22.51.61.31.6-1.61.61.61.51.31.61.61.61.3-1.6-1.61.51.61.11.5
Change in fecal boli incidents, locomotor task0.80.81.0-0.9-0.6-0.90.9-0.9-0.9-0.9-0.9-0.9-1.0-0.9-0.81.01.0-0.9-1.0-0.3-0.6
Time >=10cm from walls, locomotor time 10.10.10.8-0.10.3-0.10.1-0.1-0.1-0.2-0.1-0.2-0.2-0.2-0.20.20.2-0.3-0.20.70.9
Bouts of movement, locomotor time 10.00.00.10.0-0.1-0.00.0-0.0-0.0-0.00.4-0.0-0.0-0.00.30.00.00.1-0.1-0.10.2
Total resting periods, locomotor time 10.30.30.90.50.50.5-0.50.50.50.50.90.50.50.50.8-0.5-0.50.60.40.50.8
Rest time, locomotor task time 10.50.61.80.70.70.7-0.70.70.70.71.30.60.60.61.3-0.6-0.60.50.60.70.8
Distance moved, locomotor task time 10.00.00.1-0.2-0.0-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.20.2-0.2-0.30.1-0.2
Vertical activity count, locomotor time 10.61.52.3-1.2-1.1-1.21.2-1.2-1.2-1.2-1.5-1.2-1.2-1.2-1.51.21.2-1.3-1.1-1.0-1.0
Time >=10cm from walls, locomotor time 20.50.70.90.90.70.9-1.01.01.00.90.61.01.00.90.5-0.9-0.90.80.80.60.8
Bouts of movement, locomotor time 22.13.33.7-1.9-1.9-1.91.9-1.9-1.9-1.9-1.5-1.9-1.9-1.9-1.61.91.9-1.9-1.8-1.8-1.8
Total resting periods, locomotor time 22.13.74.1-2.0-1.9-2.02.0-2.0-2.0-2.0-1.6-2.0-2.0-2.0-1.61.91.9-2.0-1.8-1.8-1.9
Rest time, locomotor task time 20.10.10.40.10.40.1-0.10.10.10.10.60.00.00.00.5-0.00.0-0.20.00.60.5
Distance moved, locomotor task time 20.00.00.10.2-0.00.2-0.20.20.20.2-0.10.20.20.2-0.1-0.2-0.20.30.1-0.1-0.1
Vertical activity count, locomotor time 20.10.10.3-0.2-0.3-0.20.2-0.2-0.1-0.2-0.5-0.2-0.1-0.2-0.50.10.1-0.2-0.0-0.5-0.5
Light reinforcement 12.15.16.32.31.92.3-2.32.32.32.42.32.42.42.42.4-2.4-2.42.52.41.41.4
Light reinforcement 20.61.01.31.00.71.0-1.01.11.11.10.91.11.11.10.9-1.1-1.11.11.10.2-0.0
Bone: marrow area8.117.719.1-4.3-4.4-4.34.3-4.3-4.3-4.3-4.2-4.3-4.3-4.3-4.24.24.2-4.1-4.2-4.3-3.5
Bone: maximum diameter3.56.68.3-2.7-2.5-2.62.6-2.7-2.6-2.6-2.4-2.7-2.7-2.7-2.42.72.7-2.9-2.5-2.3-1.6
Bone: maximum force16.930.031.5-5.6-5.6-5.65.6-5.6-5.6-5.6-5.5-5.5-5.5-5.5-5.55.55.5-5.3-5.5-4.9-4.9
Bone: maximum moment18.332.033.8-5.8-5.8-5.85.8-5.8-5.8-5.7-5.7-5.7-5.7-5.7-5.75.75.6-5.4-5.7-5.2-5.1
Mean time between licks in bursts0.00.10.40.40.30.3-0.30.40.30.30.20.40.40.40.2-0.3-0.40.60.30.30.2
Mean num. licks in bursts0.10.20.9-0.2-0.7-0.30.3-0.2-0.3-0.2-0.3-0.2-0.2-0.2-0.30.20.10.1-0.2-0.9-0.8
Cd content in liver0.70.80.90.90.70.9-0.90.90.90.90.90.90.90.90.9-0.9-0.91.00.80.70.6
Co content in liver0.30.30.60.50.40.6-0.60.60.60.60.70.60.60.60.8-0.6-0.50.20.70.40.5
Cu content in liver0.91.11.5-1.1-0.5-1.11.1-1.1-1.1-1.1-1.0-1.1-1.1-1.1-1.01.21.2-1.2-1.20.2-0.3
Fe content in liver1.92.32.71.61.41.6-1.61.61.61.61.61.61.61.61.6-1.6-1.61.41.51.11.3
K content in liver0.00.00.2-0.10.0-0.00.0-0.0-0.0-0.1-0.0-0.1-0.0-0.10.00.10.1-0.4-0.10.30.2
Mg content in liver0.20.20.70.30.50.4-0.40.40.40.40.50.30.40.30.5-0.4-0.30.10.40.80.3
Mn content in liver0.00.00.0-0.0-0.1-0.10.1-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.10.10.10.1-0.10.00.1
Na content in liver0.00.00.00.2-0.00.1-0.20.20.20.20.00.20.20.20.1-0.2-0.20.00.10.1-0.1
Rb content in liver0.30.42.30.31.10.3-0.30.30.30.20.50.20.20.20.4-0.2-0.1-0.20.11.51.3
Se content in liver2.12.54.31.51.81.6-1.61.51.61.51.71.51.51.51.7-1.5-1.41.21.51.82.1
Sr content in liver1.21.11.3-1.1-0.6-1.11.1-1.1-1.1-1.1-1.0-1.1-1.1-1.1-1.11.11.2-1.0-1.1-0.1-0.7
Zn content in liver1.11.21.71.11.21.1-1.11.11.11.11.11.11.11.11.1-1.1-1.01.01.11.30.9
Bone: minimum diameter9.617.418.6-4.3-4.1-4.34.3-4.3-4.3-4.3-4.1-4.3-4.3-4.3-4.14.24.2-4.2-4.2-3.7-3.6
Time in familiar zone, hab. session 10.20.20.40.40.40.4-0.40.40.40.40.30.40.40.40.3-0.4-0.40.50.40.6-0.2
Time in novel zone, hab. session 10.20.20.3-0.4-0.3-0.40.4-0.4-0.4-0.4-0.3-0.5-0.5-0.5-0.40.50.5-0.5-0.4-0.40.1
Total zone transitions, hab. session 10.30.40.50.70.40.7-0.70.70.70.70.50.70.70.70.5-0.7-0.70.60.70.10.3
Total locomotion distance, hab. session 10.00.00.4-0.00.2-0.00.1-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.10.10.10.1-0.20.30.6
Locomotion velocity, hab. session 10.00.00.2-0.10.1-0.20.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.20.20.2-0.0-0.30.20.5
Time in familiar zone, hab. session 20.60.61.8-0.7-0.9-0.80.7-0.7-0.8-0.7-0.8-0.7-0.7-0.7-0.70.60.6-0.6-0.7-0.9-1.3
Time in novel zone, hab. session 20.50.51.90.61.00.6-0.60.60.60.60.60.60.60.50.6-0.5-0.50.50.51.11.4
Total zone transitions, hab. session 20.30.30.40.60.50.6-0.60.60.60.60.50.60.60.60.6-0.6-0.60.50.50.60.4
Total locomotion distance, hab. session 20.10.10.30.30.50.3-0.20.20.20.30.40.30.20.20.3-0.2-0.20.40.20.60.6
Locomotion velocity, hab. session 20.00.00.30.20.40.1-0.10.10.10.10.20.10.10.10.2-0.1-0.10.30.00.50.4
Novel to familiar place preference ratio1.61.72.0-1.4-1.0-1.41.4-1.4-1.4-1.4-1.3-1.4-1.4-1.4-1.41.41.4-1.4-1.4-0.8-0.9
Novelty place preference1.11.21.5-1.2-0.7-1.21.2-1.2-1.2-1.2-1.1-1.2-1.2-1.2-1.11.21.2-1.2-1.2-0.4-0.6
Time in novel zone, NPP test0.91.01.2-1.0-0.6-1.01.0-1.1-1.1-1.1-1.0-1.1-1.1-1.1-1.01.11.1-1.1-1.1-0.3-0.4
Total zone transitions, NPP test1.62.33.91.51.81.5-1.51.51.51.41.41.41.41.41.4-1.4-1.41.31.32.02.0
Total locomotion distance, NPP test2.02.74.61.72.01.6-1.61.51.61.51.61.51.51.51.6-1.5-1.51.61.42.12.1
Locomotion velocity, NPP test1.11.63.31.21.61.2-1.21.11.21.11.31.11.11.11.2-1.1-1.11.21.11.81.7
Intraocular pressure7.210.311.03.23.33.3-3.23.23.23.33.33.23.23.23.3-3.2-3.23.33.33.12.7
Delta distance traveled before/after self-admin0.00.00.1-0.1-0.1-0.10.1-0.1-0.1-0.00.3-0.1-0.1-0.10.10.00.1-0.1-0.1-0.1-0.4
Delta ambulatory time before/after self-admin0.00.10.30.20.10.2-0.20.20.20.20.60.20.20.20.4-0.2-0.20.10.20.1-0.1
Parametrial fat weight0.92.23.01.51.31.6-1.61.61.61.61.31.61.61.61.4-1.6-1.61.41.70.90.7
Pavlov. Cond. lever latency0.20.20.6-0.30.0-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.60.60.5-0.1-0.70.60.4
Pavlov. Cond. magazine entry latency0.10.21.5-0.0-0.90.0-0.00.10.00.1-0.00.10.10.10.0-0.2-0.20.20.2-1.2-1.0
Pavlov. Cond. change in total contacts0.20.21.8-0.2-1.0-0.10.1-0.1-0.1-0.1-0.2-0.1-0.1-0.1-0.0-0.00.0-0.30.1-1.3-1.1
Pavlov. Cond. index score0.10.21.4-0.2-0.8-0.10.1-0.0-0.0-0.0-0.1-0.00.0-0.00.0-0.1-0.0-0.30.2-1.2-0.9
Pavlov. Cond. latency score0.10.11.0-0.1-0.60.0-0.00.00.10.10.00.10.10.10.1-0.1-0.1-0.20.3-1.0-0.8
Pavlov. Cond. lever contacts0.50.61.00.70.10.8-0.80.80.80.80.70.80.80.80.8-0.9-0.90.51.0-0.6-0.3
Pavlov. Cond. magazine entry number0.10.11.00.00.7-0.00.0-0.1-0.0-0.1-0.0-0.1-0.1-0.1-0.10.10.1-0.0-0.21.00.6
Pavlov. Cond. intertrial magazine entries0.91.15.70.91.60.8-0.80.70.80.71.00.70.70.70.9-0.6-0.60.70.51.82.4
Pavlov. Cond. lever-magazine prob. diff.0.20.32.0-0.4-1.0-0.30.3-0.3-0.3-0.3-0.3-0.3-0.2-0.3-0.20.20.2-0.5-0.1-1.4-1.1
Pavlov. Cond. response bias0.20.20.70.3-0.30.4-0.40.40.40.40.40.40.40.40.5-0.5-0.50.30.5-0.8-0.4
Pavlov. Cond. lever latency0.30.31.4-0.5-1.0-0.50.5-0.4-0.5-0.4-0.6-0.4-0.4-0.4-0.60.40.4-0.3-0.4-1.2-0.9
Pavlov. Cond. magazine entry latency0.80.91.4-1.0-0.4-1.01.0-1.1-1.0-1.1-0.8-1.1-1.1-1.1-0.81.21.2-1.1-1.1-0.20.4
Pavlov. Cond. change in total contacts1.11.82.8-1.5-0.9-1.41.4-1.4-1.4-1.4-1.3-1.5-1.5-1.5-1.31.51.5-1.7-1.4-0.5-0.9
Pavlov. Cond. index score0.40.60.9-0.8-0.0-0.80.8-0.8-0.8-0.8-0.5-0.9-0.9-0.9-0.60.90.9-0.9-0.90.50.4
Pavlov. Cond. latency score0.40.50.7-0.70.1-0.70.7-0.7-0.7-0.7-0.4-0.8-0.8-0.8-0.50.80.9-0.9-0.80.50.5
Pavlov. Cond. lever contacts0.10.21.20.30.80.3-0.30.20.30.20.40.20.20.20.4-0.2-0.20.20.31.10.8
Pavlov. Cond. magazine entry number1.82.23.01.60.81.5-1.61.61.61.61.21.71.71.71.3-1.7-1.71.71.70.4-0.0
Pavlov. Cond. intertrial magazine entries5.27.98.92.92.52.9-2.92.92.92.92.73.03.03.02.8-3.0-3.02.93.02.21.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.2-0.9-0.1-0.90.9-1.0-0.9-1.0-0.7-1.0-1.0-1.0-0.71.11.1-1.1-1.00.40.3
Pavlov. Cond. response bias0.10.10.4-0.10.4-0.10.1-0.2-0.2-0.20.1-0.2-0.2-0.2-0.00.20.2-0.2-0.20.70.5
Time in closed arm before self-admin2.32.93.3-1.7-1.5-1.81.8-1.8-1.8-1.8-1.8-1.7-1.7-1.7-1.71.71.7-1.7-1.6-1.4-1.6
Time in closed arm after self-admin0.20.20.8-0.5-0.7-0.50.5-0.4-0.5-0.40.4-0.4-0.4-0.40.30.40.4-0.3-0.3-0.7-0.9
Time in open arm before self-admin0.10.10.60.30.50.3-0.20.20.20.20.50.20.20.20.3-0.2-0.20.30.10.70.8
Time in open arm after self-admin0.10.10.50.20.50.2-0.20.20.20.2-0.50.20.20.2-0.4-0.2-0.20.10.00.60.7
Bone: periosteal estimation12.827.029.0-5.4-5.1-5.35.3-5.3-5.3-5.3-5.1-5.3-5.3-5.3-5.15.35.3-5.3-5.1-4.7-4.2
Bone: periosteal perimeter11.119.020.4-4.5-4.4-4.54.5-4.5-4.4-4.4-4.3-4.5-4.4-4.5-4.34.44.4-4.5-4.3-3.9-3.7
Bone: post-yield work9.714.115.7-3.8-4.0-3.83.8-3.8-3.8-3.8-3.8-3.8-3.8-3.8-3.83.83.7-3.6-3.8-3.8-3.3
Progressive ratio test 1 active lever presses6.58.19.02.93.02.9-2.92.92.92.92.82.82.82.82.9-2.8-2.82.62.72.92.8
Progressive ratio test 1 breakpoint6.27.68.62.82.92.8-2.82.82.82.82.82.72.72.72.8-2.7-2.72.52.62.82.7
Progressive ratio test 1 inactive lever presses1.82.63.81.71.31.7-1.81.81.81.81.31.81.81.81.3-1.8-1.81.72.00.70.5
Progressive ratio test 2 active lever presses2.12.42.91.61.51.7-1.71.71.71.71.31.71.71.71.3-1.7-1.61.41.71.21.1
Progressive ratio test 2 breakpoint2.02.32.71.61.41.6-1.61.61.71.61.31.61.61.61.3-1.6-1.61.41.61.21.1
Progressive ratio test 2 inactive lever presses1.11.82.51.41.11.5-1.51.51.51.51.11.51.51.51.2-1.5-1.51.31.60.70.6
Incentive Sensitization - Responses0.20.31.2-0.5-0.5-0.40.4-0.4-0.3-0.4-0.7-0.4-0.4-0.4-0.70.30.4-0.5-0.2-0.7-1.1
Incentive Sensitization - Breakpoint0.10.20.9-0.3-0.4-0.30.3-0.3-0.2-0.3-0.6-0.3-0.3-0.3-0.60.20.2-0.4-0.1-0.6-1.0
Sum of active levers in priming session hrs 5-60.10.10.3-0.10.0-0.10.1-0.1-0.2-0.10.3-0.1-0.2-0.10.40.20.2-0.0-0.40.30.5
Progressive ratio0.40.72.20.71.30.7-0.70.60.70.70.80.60.60.60.7-0.6-0.60.50.71.51.3
Food seeking constrained by brief footshock1.21.53.61.21.71.2-1.21.21.21.11.01.11.11.10.9-1.1-1.10.91.11.91.7
Seeking ratio, punishment vs. effort0.00.00.10.1-0.20.1-0.10.10.10.1-0.10.10.10.1-0.1-0.1-0.10.1-0.0-0.2-0.2
Retroperitoneal fat weight0.41.53.01.21.21.2-1.21.21.21.21.41.21.21.21.4-1.2-1.11.11.21.01.7
Reaction time number correct1.12.22.5-1.5-1.4-1.51.6-1.5-1.6-1.5-1.5-1.5-1.5-1.5-1.61.51.5-1.2-1.5-1.3-1.3
Reaction time mean minus median4.611.412.93.53.33.5-3.43.43.43.53.63.43.43.43.6-3.4-3.43.33.52.82.8
Reaction time mean minus median AUC3.17.88.72.92.62.9-2.82.92.82.93.02.92.82.93.0-2.8-2.82.82.92.32.3
Reaction time num false alarms1.62.32.81.51.61.5-1.51.51.51.51.71.51.51.51.6-1.4-1.41.51.41.61.5
Reaction time num false alarms AUC2.03.13.71.81.81.8-1.81.81.81.81.91.81.81.81.9-1.7-1.71.81.71.71.6
Reaction time trials correct on left1.12.22.5-1.5-1.4-1.51.6-1.5-1.6-1.5-1.5-1.5-1.5-1.5-1.61.51.5-1.2-1.5-1.3-1.3
Reaction time trials on left0.91.72.0-1.3-1.3-1.41.4-1.4-1.4-1.4-1.3-1.3-1.4-1.3-1.41.41.3-1.0-1.3-1.1-1.1
Reaction time mean0.71.21.31.11.11.1-1.11.11.11.11.11.11.11.11.1-1.1-1.00.81.11.01.1
Reaction time mean AUC0.40.70.80.80.90.8-0.80.80.80.80.80.80.80.80.8-0.8-0.80.50.80.80.9
Median of all reaction times0.00.00.10.00.10.0-0.00.00.0-0.0-0.1-0.00.0-0.0-0.10.00.0-0.3-0.00.20.3
Reaction time omissions9.714.115.43.93.63.9-3.93.93.83.83.73.93.93.83.7-3.8-3.83.93.93.23.2
Reaction time false alarm rate2.63.64.21.91.91.9-1.91.92.01.92.01.91.91.92.0-1.9-1.91.81.91.71.7
Reaction time premature initiation rate5.67.79.72.82.32.9-2.92.92.92.93.02.92.92.93.1-2.9-2.92.63.11.81.7
Reaction time premature initiations1.93.44.71.91.41.9-1.91.91.91.92.11.91.91.92.1-2.0-2.01.92.21.00.9
Std. dev. reaction times5.09.310.13.13.03.1-3.13.13.13.13.23.13.13.13.2-3.0-3.02.93.12.82.8
Reaction time trials completed0.91.72.0-1.3-1.3-1.41.4-1.4-1.4-1.4-1.3-1.3-1.4-1.3-1.41.41.3-1.0-1.3-1.1-1.1
Reaction time trials AUC1.52.83.2-1.7-1.6-1.71.8-1.7-1.8-1.7-1.7-1.7-1.7-1.7-1.81.71.7-1.3-1.7-1.4-1.5
Run reversals in cocaine runway, females0.20.21.5-0.3-0.6-0.30.3-0.2-0.3-0.2-0.3-0.2-0.2-0.2-0.40.20.2-0.1-0.3-0.8-1.2
Run reversals in cocaine runway, males1.21.21.51.10.91.1-1.11.11.11.11.21.11.11.11.2-1.1-1.11.11.10.70.7
Latency to leave start box in cocaine runway0.00.00.00.1-0.00.1-0.20.20.20.10.20.10.20.20.2-0.2-0.20.20.2-0.20.0
Latency to leave start box in cocaine runway, F1.01.11.41.10.91.1-1.11.11.11.11.01.11.11.11.0-1.1-1.11.21.10.71.0
Latency to leave start box in cocaine runway, M1.81.72.0-1.4-1.3-1.31.3-1.3-1.3-1.3-1.0-1.3-1.3-1.3-1.11.31.3-1.4-1.3-1.2-1.3
Std. dev. time between licks in bursts1.11.52.11.21.51.2-1.21.21.21.21.31.21.21.21.3-1.2-1.21.01.31.41.3
Total sessions with >9 infusions2.73.33.91.81.81.9-1.91.92.01.91.61.91.91.81.8-1.9-1.81.52.01.51.5
Short access day 1 total inactive lever presses1.92.52.91.61.61.7-1.71.71.71.71.41.71.71.71.6-1.7-1.71.51.61.41.1
Short access day 10 total inactive lever presses0.00.10.20.30.00.2-0.20.30.20.30.50.30.30.30.4-0.3-0.30.50.3-0.1-0.1
Short access day 1 total infusions0.91.21.81.11.41.1-1.11.11.21.10.81.11.11.10.9-1.1-1.00.91.21.31.1
Short access day 10 total infusions2.02.53.01.61.61.7-1.71.61.71.71.71.61.61.61.7-1.6-1.61.21.51.41.4
Short access total infusions3.24.04.82.02.22.1-2.12.12.12.11.82.02.02.01.9-2.0-2.01.62.12.02.0
Short access day 1 locomotion0.30.30.50.60.70.6-0.60.60.60.60.40.60.60.60.5-0.6-0.50.40.70.70.5
Short access day 10 total locomotion0.20.30.40.60.60.6-0.60.60.60.60.50.60.60.60.6-0.6-0.60.60.50.50.6
Short access total locomotion1.01.31.41.11.11.2-1.21.21.21.21.11.11.11.11.2-1.1-1.11.01.11.00.9
One hour access (0.3 mA shock)0.20.20.50.3-0.20.4-0.40.40.50.50.40.50.50.50.2-0.5-0.50.30.6-0.7-0.6
Compulsive drug intake0.00.10.4-0.1-0.5-0.10.1-0.1-0.1-0.10.2-0.1-0.0-0.00.00.00.0-0.0-0.1-0.6-0.5
One hour access (shock baseline)0.00.10.40.0-0.20.1-0.10.10.20.2-0.10.10.10.1-0.1-0.2-0.2-0.00.4-0.6-0.7
Social response proportion0.20.30.50.50.70.5-0.50.50.50.50.50.50.50.50.5-0.5-0.50.30.60.70.4
Social responses7.810.111.23.23.23.2-3.23.23.33.33.33.23.23.23.3-3.2-3.23.03.32.92.5
Social time0.10.10.5-0.2-0.5-0.20.2-0.2-0.2-0.2-0.5-0.2-0.1-0.1-0.50.10.1-0.1-0.1-0.7-0.7
Soleus weight0.72.13.5-1.4-1.9-1.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.31.31.3-1.4-1.4-1.7-1.6
Bone: stiffness19.632.034.1-5.8-5.8-5.85.8-5.7-5.7-5.7-5.7-5.7-5.7-5.7-5.75.65.6-5.5-5.5-5.3-5.6
Tibialis anterior weight1.24.111.2-1.9-2.6-1.81.8-1.7-1.7-1.7-2.1-1.7-1.6-1.7-1.91.61.6-2.1-1.5-3.0-3.3
Time to tail flick, vehicle, before self-admin1.41.41.91.31.11.2-1.21.21.21.21.11.21.21.21.0-1.2-1.31.41.31.01.0
Time to tail flick, vehicle, after self-admin0.20.31.2-0.4-0.8-0.40.4-0.4-0.4-0.4-0.5-0.3-0.3-0.3-0.40.30.3-0.2-0.4-1.1-0.9
Time to tail flick, test, before self-admin0.10.10.30.50.30.4-0.40.40.40.40.10.40.40.40.1-0.4-0.50.50.20.40.2
Time to tail flick, test, after self-admin1.01.02.1-0.9-1.1-0.91.0-0.9-1.0-0.9-1.2-0.9-0.9-0.9-1.30.90.9-0.8-0.9-1.1-1.4
Delta time to tail flick, vehicle, before/after SA0.50.51.1-0.7-0.9-0.70.7-0.7-0.7-0.7-0.4-0.7-0.7-0.7-0.40.70.7-0.7-0.7-1.0-0.9
Delta time to tail flick, test, before/after SA0.30.30.6-0.6-0.6-0.50.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.40.50.5-0.5-0.2-0.7-0.7
Tibia length7.019.224.5-4.6-3.8-4.54.5-4.6-4.5-4.5-4.3-4.6-4.6-4.6-4.44.64.6-4.9-4.5-2.9-3.2
Ambulatory time before self-admin2.02.94.71.72.01.7-1.71.71.61.61.51.71.61.61.6-1.6-1.61.71.62.21.9
Ambulatory time after self-admin1.72.03.41.31.61.3-1.31.31.31.31.81.31.31.31.7-1.2-1.21.21.21.81.5
Bone: tissue strength1.51.51.9-1.2-1.3-1.21.2-1.2-1.3-1.2-1.4-1.2-1.2-1.2-1.41.21.1-1.0-1.3-1.2-1.2
Total heroin consumption0.81.01.5-1.0-0.9-1.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.71.01.0-1.0-1.2-0.7-0.6
Bone: trabecular number6.09.910.9-3.3-2.8-3.33.3-3.3-3.3-3.3-3.2-3.3-3.3-3.3-3.33.33.3-3.2-3.2-2.2-2.4
Bone: trabecular spacing2.53.33.91.81.61.9-1.91.91.91.91.91.91.91.92.0-1.9-1.91.71.91.31.5
Bone: trabecular thickness0.10.10.90.1-0.00.2-0.20.20.20.2-0.00.20.20.20.0-0.3-0.30.20.3-0.2-0.9
Bone: trabecular tissue density0.00.11.2-0.0-0.2-0.00.0-0.0-0.00.0-0.00.00.00.00.0-0.1-0.10.10.0-0.2-1.1
Water consumed over 24 hours0.10.10.2-0.30.3-0.30.3-0.3-0.3-0.3-0.2-0.3-0.3-0.3-0.30.30.3-0.2-0.40.4-0.2
Number of responses in last shaping day0.10.10.20.30.30.4-0.40.40.40.40.10.40.40.40.1-0.4-0.40.30.40.2-0.3