Spats2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_039078932.1 0.07 0.07 2.4e-05 0.04 0.04 0.04 0.04 2.4e-05 1.3e-05 3.1e-05 2.9e-05
2 OFC gene expression Spats2 0.28 0.17 9.8e-06 0.1 0.16 0.12 0.1 2.9e-03 1.4e-04 8.5e-04 2.1e-03
3 RMTg gene expression Spats2 0.16 0.14 3.3e-03 0.05 0.05 0.03 0.05 2.1e-02 1.5e-02 4.7e-02 1.8e-02
4 RMTg mRNA stability Spats2 0.13 0.12 4.2e-03 0.08 0.09 0.08 0.08 3.8e-03 2.5e-03 4.5e-03 4.2e-03
5 BLA gene expression Spats2 0.23 0.15 3.1e-12 0.21 0.22 0.22 0.21 1.2e-11 3.3e-12 7.5e-12 1.5e-11
6 IL gene expression Spats2 0.16 0.12 7.4e-04 0.13 0.13 0.11 0.12 4.3e-04 4.6e-04 1.4e-03 9.7e-04
7 NAcc gene expression Spats2 0.12 0.06 0.0e+00 0.18 0.18 0.17 0.18 2.1e-20 3.3e-20 7.3e-20 2.6e-20
8 LHb gene expression Spats2 0.26 0.14 2.0e-06 0.25 0.19 0.2 0.21 1.2e-06 3.1e-05 2.2e-05 9.4e-06
9 PL isoform ratio NM_001395111.1 0.02 0.02 8.2e-03 0.01 0.01 0.01 0.01 2.1e-02 1.7e-02 3.0e-02 3.7e-02
10 pVTA gene expression Spats2 0.18 0.13 4.6e-07 0.14 0.16 0.15 0.14 1.2e-06 2.8e-07 3.7e-07 2.0e-06
11 Adipose alternative TSS XM_039078933.1 0.03 0.03 1.7e-03 0.02 0.02 0.02 0.02 4.1e-03 2.9e-03 4.1e-03 4.6e-03
12 Liver gene expression Spats2 0.12 0.11 1.8e-11 0.08 0.09 0.08 0.09 1.2e-09 8.0e-10 1.6e-09 1.1e-09
13 PL gene expression Spats2 0.25 0.13 0.0e+00 0.25 0.26 0.26 0.26 2.0e-27 2.1e-28 2.4e-28 1.9e-28
14 Adipose intron excision ratio chr7_130322428_130323680 0.04 0.04 4.9e-04 0.02 0.02 0.02 0.02 8.8e-04 1.1e-03 1.3e-03 9.9e-04
15 Brain gene expression Spats2 0.15 0.09 1.1e-16 0.19 0.18 0.18 0.18 3.5e-17 1.3e-16 1.5e-16 1.7e-16
16 Adipose gene expression Spats2 0.09 0.08 2.0e-08 0.07 0.06 0.07 0.06 8.2e-08 9.3e-08 7.1e-08 9.0e-08
17 RMTg isoform ratio XM_039078933.1 0.13 0.15 9.1e-03 0.06 0.03 0.04 0.01 9.6e-03 6.3e-02 4.0e-02 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density10.417.419.0-4.2-4.2-4.2-4.2-4.24.24.24.24.2-4.2-4.24.2-4.44.34.2-4.0-3.4
Area under the delay curve1.01.11.4-1.1-1.0-1.0-1.0-1.01.11.11.11.0-1.0-1.01.0-1.01.00.9-1.2-1.0
BMI with tail4.514.417.0-4.0-3.9-3.8-3.8-3.83.83.83.83.8-3.8-3.83.7-3.73.63.7-4.1-3.7
BMI without tail0.00.00.3-0.10.10.10.10.1-0.0-0.0-0.0-0.10.10.1-0.20.2-0.3-0.3-0.4-0.5
Body weight6.225.830.7-5.3-5.2-5.1-5.1-5.15.15.15.15.1-5.2-5.15.0-5.04.94.9-5.5-4.4
Weight adjusted by age1.82.12.7-1.4-1.5-1.5-1.5-1.41.41.41.41.5-1.5-1.51.5-1.51.41.5-1.6-0.8
Bone surface12.321.722.9-4.7-4.7-4.7-4.7-4.74.64.64.64.7-4.7-4.74.7-4.84.84.6-4.5-4.0
Bone volume9.416.016.9-4.1-4.1-4.1-4.1-4.04.04.04.04.0-4.0-4.04.0-4.14.13.9-3.8-3.7
Breakpoint value in progressive ratio session0.20.20.3-0.5-0.5-0.5-0.5-0.50.30.30.30.5-0.5-0.50.5-0.40.40.6-0.4-0.4
Number of licking bursts0.70.81.90.90.80.90.90.9-1.1-1.1-1.1-0.80.80.8-0.80.8-0.8-0.90.31.4
Context. condit. distance diff. score0.20.30.3-0.5-0.5-0.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.50.50.6-0.5-0.4
Locomotion velocity, session 11.41.54.31.41.21.21.21.2-1.2-1.2-1.2-1.11.11.1-1.01.1-1.1-1.01.12.1
Locomotion distance, session 12.83.54.42.01.91.91.91.9-1.8-1.8-1.8-1.91.91.9-1.81.9-1.9-1.72.11.8
Locomotion velocity, session 20.20.20.30.50.50.50.50.5-0.5-0.5-0.5-0.50.50.5-0.50.4-0.4-0.50.50.5
Locomotion distance, session 22.43.33.81.91.91.81.81.8-1.8-1.8-1.8-1.81.81.8-1.81.7-1.7-1.71.92.0
Locomotion velocity, session 34.35.05.52.32.32.22.22.3-2.3-2.3-2.3-2.22.22.2-2.22.1-2.1-2.22.22.3
Locomotion distance, session 35.05.56.52.42.42.42.42.4-2.4-2.4-2.4-2.42.42.4-2.42.2-2.2-2.52.51.7
Stereotopy head waving bouts, day 31.01.11.8-1.0-1.1-1.1-1.1-1.10.90.90.91.1-1.1-1.11.2-1.31.31.1-1.3-0.1
Stereotopy head waving duration, day 30.50.60.8-0.6-0.8-0.8-0.8-0.80.60.60.60.8-0.8-0.80.9-0.90.90.9-0.90.2
Locomotion velocity, session 70.50.62.80.90.70.70.70.7-0.8-0.8-0.8-0.60.60.6-0.60.4-0.4-0.60.61.7
Locomotion distance, session 72.22.84.81.81.71.71.71.7-1.7-1.7-1.7-1.61.61.6-1.61.4-1.4-1.61.52.2
Stereotopy head waving bouts, day 70.80.91.6-1.0-1.0-1.0-1.0-0.90.80.80.81.0-1.0-1.01.0-1.11.10.9-1.2-0.6
Stereotopy head waving duration, day 71.21.42.0-1.3-1.2-1.2-1.2-1.21.11.11.11.2-1.3-1.21.2-1.21.21.1-1.4-1.0
Locomotion velocity, session 80.00.00.30.10.00.00.00.0-0.1-0.1-0.10.0-0.0-0.00.1-0.0-0.00.1-0.10.5
Locomotion distance, session 81.11.72.11.41.31.31.31.3-1.2-1.2-1.2-1.31.31.3-1.31.3-1.3-1.21.41.3
Degree of sensitization distance0.40.40.7-0.6-0.6-0.6-0.6-0.60.60.60.60.6-0.7-0.70.7-0.70.70.7-0.8-0.0
Degree of sensitization stereotypy0.20.20.6-0.5-0.5-0.4-0.4-0.40.40.40.40.4-0.4-0.40.4-0.30.30.3-0.6-0.8
Conditioned locomotion0.00.00.1-0.1-0.1-0.2-0.2-0.10.00.00.00.2-0.2-0.20.2-0.30.20.1-0.00.1
Cocaine response after cond. corrected0.00.00.00.00.00.00.00.00.00.00.0-0.00.00.0-0.00.1-0.0-0.0-0.0-0.1
Cocaine response after cond. not corrected0.50.50.60.70.70.70.70.7-0.7-0.7-0.7-0.70.70.7-0.80.8-0.7-0.70.70.4
Cocaine response before conditioning3.44.14.42.12.02.02.02.1-2.0-2.0-2.0-2.02.02.0-2.02.0-2.0-2.02.11.7
Saline control response0.10.10.2-0.3-0.4-0.4-0.4-0.40.30.30.30.4-0.4-0.40.4-0.50.50.4-0.30.2
Bone: connectivity density7.311.513.0-3.4-3.5-3.5-3.5-3.53.33.33.33.5-3.5-3.53.5-3.63.63.4-3.3-2.4
Bone: cortical apparent density0.30.40.60.60.60.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.5-0.5-0.60.70.4
Bone: cortical area9.314.016.3-3.8-3.8-3.8-3.8-3.73.63.63.63.8-3.9-3.83.8-3.83.83.7-4.0-2.9
Bone: cortical porosity0.50.61.60.70.80.80.80.8-0.6-0.6-0.6-0.80.80.8-0.80.8-0.8-0.71.3-0.1
Bone: cortical porosity0.91.02.31.01.01.01.01.0-0.9-0.9-0.9-1.11.11.1-1.01.0-1.0-1.01.50.2
Bone: cortical thickness3.15.17.7-2.3-2.3-2.3-2.3-2.22.12.12.12.4-2.4-2.32.3-2.32.32.2-2.8-1.6
Bone: cortical thickness0.10.10.4-0.1-0.2-0.2-0.2-0.20.00.00.00.3-0.3-0.30.3-0.20.30.2-0.60.6
Bone: cortical tissue density0.40.50.80.70.70.70.70.7-0.7-0.7-0.7-0.70.70.7-0.70.6-0.6-0.70.90.5
Condit. Reinf. active minus inactive responses0.10.10.30.30.30.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.2-0.2-0.20.30.5
Condit. Reinf. active-inactive response ratio0.20.20.3-0.4-0.5-0.5-0.5-0.50.50.50.50.5-0.5-0.50.5-0.60.60.5-0.2-0.1
Condit. Reinf. active responses0.60.81.20.90.90.90.90.9-0.9-0.9-0.9-0.90.90.9-0.80.8-0.8-0.90.71.1
Condit. Reinf. inactive responses2.93.43.61.91.91.91.91.9-1.9-1.9-1.9-1.91.91.9-1.81.9-1.9-1.91.61.6
Incentive salience index mean0.00.00.1-0.1-0.1-0.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.10.10.1-0.20.1
Condit. Reinf. lever presses0.10.20.6-0.5-0.4-0.4-0.4-0.40.40.40.40.4-0.4-0.40.3-0.30.30.2-0.6-0.8
Condit. Reinf. active minus inactive responses0.00.10.9-0.10.00.00.00.0-0.0-0.0-0.0-0.00.10.0-0.10.1-0.1-0.10.2-0.9
Condit. Reinf. active-inactive response ratio0.30.30.80.20.40.40.40.5-0.4-0.4-0.4-0.50.50.5-0.60.6-0.6-0.60.5-0.9
Condit. Reinf. active responses0.10.20.30.30.40.40.40.4-0.4-0.4-0.4-0.40.40.4-0.50.4-0.4-0.50.6-0.3
Condit. Reinf. inactive responses0.60.81.00.90.90.90.90.9-0.8-0.8-0.8-0.90.90.9-0.80.8-0.8-0.81.01.0
Condit. Reinf. lever presses0.00.00.0-0.0-0.0-0.0-0.0-0.0-0.0-0.0-0.00.00.0-0.00.0-0.00.1-0.00.2-0.1
Condit. Reinf. lever reinforcers received0.40.61.00.70.80.80.80.8-0.8-0.8-0.8-0.80.80.8-0.80.8-0.8-0.81.00.2
Conditioned reinforcement - actives1.61.62.11.21.31.31.31.3-1.2-1.2-1.2-1.31.31.3-1.31.3-1.5-1.41.10.8
Conditioned reinforcement - inactives2.32.63.01.61.61.61.61.6-1.7-1.7-1.7-1.61.61.6-1.61.5-1.7-1.61.31.5
Conditioned locomotion0.50.61.20.60.70.70.70.7-1.1-1.1-1.1-0.70.70.7-0.70.6-0.9-0.70.60.5
Patch foraging indifference point 0 sec3.04.811.12.42.12.12.12.1-2.3-2.3-2.3-2.12.02.0-2.02.0-2.0-1.91.73.3
Patch foraging indifference point AUC0.30.30.60.50.50.50.50.6-0.8-0.8-0.8-0.50.50.5-0.60.4-0.5-0.70.20.3
Delay disc. indifference point, 0s delay1.31.51.9-1.3-1.2-1.2-1.2-1.21.11.11.11.2-1.2-1.21.2-1.21.11.1-1.2-1.4
Delay disc. indifference point, 16s delay0.90.91.2-1.0-1.0-1.0-1.0-1.00.70.70.71.0-1.0-1.00.9-0.90.80.9-1.1-1.0
Delay disc. indifference point, 2s delay1.82.03.1-1.4-1.3-1.3-1.3-1.41.81.81.81.3-1.3-1.31.3-1.31.41.3-1.2-1.4
Delay disc. indifference point, 24s delay1.21.21.7-1.1-1.1-1.1-1.1-1.10.90.90.91.2-1.2-1.21.1-1.11.11.1-1.3-0.8
Delay disc. indifference point, 4s delay0.40.41.1-0.7-0.6-0.6-0.6-0.60.80.80.80.6-0.6-0.60.5-0.50.60.5-0.5-1.1
Delay disc. indifference point, 8s delay2.52.63.4-1.6-1.6-1.6-1.6-1.61.61.61.61.6-1.6-1.61.6-1.61.51.5-1.9-1.2
Indifference point function ln k4.36.06.9-2.5-2.5-2.5-2.5-2.52.62.62.62.4-2.4-2.42.4-2.42.42.4-2.1-2.5
Indifference point function log k4.36.06.9-2.5-2.5-2.5-2.5-2.52.62.62.62.4-2.4-2.42.4-2.42.42.4-2.1-2.5
Patch foraging total patch changes 0 sec2.84.610.32.32.12.12.12.1-2.3-2.3-2.3-2.02.02.0-1.92.0-1.9-1.91.73.2
Patch foraging total patch changes 12 sec3.03.88.22.11.91.91.91.9-2.1-2.1-2.1-1.81.81.8-1.81.8-1.8-1.81.32.9
Patch foraging total patch changes 18 sec5.06.59.22.72.52.52.52.6-2.8-2.8-2.8-2.52.42.5-2.42.3-2.3-2.42.23.0
Patch foraging total patch changes 24 sec2.83.45.81.91.81.81.81.8-2.0-2.0-2.0-1.71.71.7-1.71.7-1.6-1.81.42.4
Patch foraging total patch changes 6 sec3.45.011.02.42.22.22.22.2-2.4-2.4-2.4-2.12.12.1-2.02.0-2.0-2.11.73.3
Patch foraging time to switch 0 sec2.33.64.02.02.01.91.91.9-1.9-1.9-1.9-1.91.91.9-1.91.9-1.8-1.82.01.8
Patch foraging water rate 0 sec2.94.75.9-2.3-2.2-2.2-2.2-2.22.02.02.02.2-2.2-2.22.1-2.22.12.0-2.4-2.1
Patch foraging water rate 12 sec3.75.66.4-2.4-2.4-2.4-2.4-2.42.32.32.32.4-2.4-2.42.4-2.52.52.4-2.2-1.8
Patch foraging water rate 18 sec0.30.30.4-0.6-0.6-0.6-0.6-0.60.70.70.70.6-0.6-0.60.6-0.50.50.6-0.5-0.5
Patch foraging water rate 24 sec3.65.06.7-2.4-2.2-2.2-2.2-2.32.32.32.32.2-2.2-2.22.2-2.12.22.1-2.1-2.6
Patch foraging water rate 6 sec4.16.08.0-2.6-2.5-2.5-2.5-2.52.52.52.52.4-2.4-2.42.4-2.42.42.2-2.3-2.8
Seeking ratio, delayed vs. immediate footshock0.30.30.6-0.6-0.6-0.6-0.6-0.60.30.30.30.6-0.6-0.60.6-0.60.50.4-0.6-0.8
Distance traveled before self-admin1.51.52.91.31.21.21.21.2-1.3-1.3-1.3-1.21.21.2-1.11.1-1.1-1.11.21.7
Distance traveled after self-admin0.30.30.80.60.50.50.50.5-0.8-0.8-0.8-0.50.50.5-0.40.4-0.4-0.40.40.9
Extensor digitorum longus weight4.116.018.8-4.3-4.1-4.0-4.0-4.04.04.04.04.0-4.0-4.03.9-3.73.63.8-4.3-4.3
Bone: elastic displacement4.65.37.32.52.32.32.32.2-2.2-2.2-2.2-2.32.32.3-2.22.2-2.2-2.02.52.7
Bone: elastic work0.00.00.1-0.0-0.1-0.1-0.1-0.20.30.30.30.1-0.1-0.10.2-0.10.20.30.40.0
Bone: endosteal estimation8.117.718.6-4.3-4.3-4.3-4.3-4.34.34.34.34.2-4.2-4.24.2-4.34.24.2-3.9-3.8
Bone: endosteal perimeter6.914.315.5-3.9-3.9-3.8-3.8-3.83.73.73.73.8-3.8-3.83.8-3.83.73.7-3.8-3.6
Epididymis fat weight0.10.30.5-0.5-0.6-0.6-0.6-0.60.50.50.50.6-0.6-0.60.6-0.70.70.6-0.6-0.1
Delta time in closed arm before/after self-admin0.20.20.3-0.5-0.5-0.5-0.5-0.50.30.30.30.5-0.5-0.50.5-0.50.50.4-0.5-0.3
Delta time in open arm before/after self-admin4.34.24.62.22.12.12.12.1-1.9-1.9-1.9-2.12.12.1-2.12.1-2.1-2.02.11.9
Diff in mean of infusions in LGA sessions1.82.02.8-1.4-1.4-1.4-1.4-1.41.71.71.71.4-1.4-1.41.4-1.31.31.4-1.2-1.3
Delay discount exponential model param0.91.01.21.01.01.01.01.0-1.1-1.1-1.1-1.01.01.0-0.90.9-0.9-0.91.11.0
Extinction: sum of active levers before priming0.60.60.8-0.7-0.7-0.7-0.7-0.80.90.90.90.7-0.7-0.70.7-0.60.70.8-0.5-0.7
Active lever presses in extinction session 60.40.40.5-0.6-0.7-0.7-0.7-0.70.60.60.60.7-0.7-0.70.7-0.60.60.7-0.6-0.5
Bone: final force11.017.719.1-4.4-4.3-4.2-4.2-4.24.34.34.34.2-4.2-4.24.2-4.14.14.1-4.1-4.1
Bone: final moment11.819.120.6-4.5-4.4-4.4-4.4-4.44.54.54.54.4-4.4-4.44.3-4.34.34.3-4.1-4.4
Food consumed during 24 hour testing period1.82.12.3-1.5-1.5-1.5-1.5-1.51.41.41.41.5-1.5-1.51.5-1.51.51.4-1.4-1.4
Glucose0.10.11.00.1-0.1-0.1-0.1-0.0-0.1-0.1-0.10.1-0.1-0.10.2-0.10.10.1-0.41.0
Heart weight0.10.10.1-0.3-0.3-0.3-0.3-0.30.30.30.30.3-0.3-0.30.3-0.20.20.4-0.1-0.3
Delay discount hyperbolic model param1.01.01.41.11.01.01.01.0-1.2-1.2-1.2-1.01.01.0-0.90.9-0.9-0.91.11.1
Intermittent access intake day 1-15 change1.51.42.01.11.21.21.21.3-1.1-1.1-1.1-1.21.31.3-1.31.2-1.3-1.41.30.3
Intermittent access intake escalation1.01.01.50.91.01.01.01.0-0.9-0.9-0.9-1.01.01.1-1.11.0-1.1-1.21.1-0.1
Intermittent access intake escalation 21.61.52.21.11.31.31.31.3-1.1-1.1-1.1-1.31.31.3-1.41.3-1.4-1.51.30.1
Intermitt. access day 1 inactive lever presses2.12.33.51.51.61.61.61.5-1.3-1.3-1.3-1.61.61.6-1.61.8-1.6-1.41.90.6
Intermitt. access day 15 inactive lever presses1.11.31.61.01.11.11.11.1-1.3-1.3-1.3-1.11.21.1-1.21.1-1.2-1.11.30.2
Intermitt. access escalation Index0.30.31.00.60.50.50.50.5-0.4-0.4-0.4-0.50.50.5-0.50.5-0.3-0.40.61.0
Intermittent access day 1 total infusions1.21.41.71.21.21.21.21.2-1.2-1.2-1.2-1.21.21.2-1.21.2-1.3-1.21.11.2
Intermittent access day 15 total infusions2.93.23.81.81.81.81.81.9-1.7-1.7-1.7-1.81.81.8-1.91.8-1.9-2.01.71.3
Intermittent access terminal intake (last 3 days)3.13.44.11.81.91.91.91.9-1.8-1.8-1.8-1.91.91.9-1.91.8-1.9-2.01.81.2
Intermittent access total infusions2.83.13.71.81.81.81.81.8-1.7-1.7-1.7-1.81.81.8-1.81.8-1.9-1.91.71.4
Intermittent access day 1 locomotion1.11.11.61.11.01.01.01.0-1.2-1.2-1.2-1.01.01.0-0.91.0-1.0-0.91.01.3
Intermittent access day 15 total locomotion1.92.02.61.41.41.41.41.4-1.6-1.6-1.6-1.41.41.4-1.41.3-1.6-1.41.31.2
Intermittent access total locomotion3.94.55.32.22.12.12.12.1-2.3-2.3-2.3-2.12.12.1-2.02.0-2.2-2.02.02.3
Intermittent access standard deviation0.50.50.70.60.70.70.70.7-0.8-0.8-0.8-0.70.70.7-0.80.8-0.8-0.80.7-0.2
Left kidney weight0.51.32.4-1.2-1.1-1.1-1.1-1.11.31.31.31.1-1.1-1.11.0-1.11.01.0-1.2-1.6
Right kidney weight2.77.59.3-2.8-2.8-2.8-2.8-2.82.82.82.82.8-2.8-2.82.7-2.82.62.6-3.1-2.3
Cocaine induced anxiety1.21.42.5-1.2-1.1-1.1-1.1-1.11.61.61.61.1-1.1-1.11.1-1.11.11.1-1.0-1.1
Post-drug Anxiety5.56.17.7-2.5-2.4-2.4-2.4-2.52.82.82.82.4-2.4-2.42.4-2.42.42.4-2.3-2.2
Baseline Anxiety0.91.01.3-1.0-1.0-1.0-1.0-1.00.90.90.91.0-1.0-1.01.0-1.01.01.0-1.1-0.6
Tail length0.10.30.50.50.50.60.60.6-0.5-0.5-0.5-0.50.50.6-0.60.5-0.6-0.70.20.4
Length with tail2.07.37.9-2.8-2.7-2.7-2.7-2.72.82.82.82.7-2.7-2.72.7-2.72.72.6-2.8-2.2
Length without tail7.516.417.1-4.1-4.1-4.1-4.1-4.14.04.04.04.1-4.1-4.14.1-4.14.14.1-4.1-3.2
Times rat made contact with spout0.10.10.20.30.30.30.30.3-0.4-0.4-0.4-0.30.30.3-0.40.4-0.4-0.40.10.1
Lifetime Intake2.93.23.91.81.81.81.81.9-1.8-1.8-1.8-1.81.81.8-1.81.7-1.9-2.01.61.6
Liver weight, left1.82.93.2-1.7-1.7-1.7-1.7-1.71.71.71.71.7-1.7-1.71.7-1.71.61.8-1.6-1.4
Liver weight, right1.52.52.7-1.6-1.6-1.6-1.6-1.61.61.61.61.6-1.6-1.61.6-1.51.61.6-1.5-1.5
Locomotor activity1.22.02.31.51.41.41.41.5-1.3-1.3-1.3-1.41.41.4-1.41.3-1.4-1.51.31.5
Locomotor testing distance3.25.46.22.42.42.42.42.4-2.2-2.2-2.2-2.32.32.3-2.32.2-2.2-2.42.32.5
Locomotor testing rearing2.53.84.12.02.02.02.02.0-1.8-1.8-1.8-2.02.02.0-2.01.9-1.9-2.01.91.9
Locomotion in novel chamber0.81.03.8-1.2-1.0-0.9-0.9-0.90.90.90.90.9-0.9-0.90.8-0.80.80.7-1.0-2.0
Locomotion in novel chamber post-restriction0.10.10.6-0.3-0.2-0.2-0.2-0.20.00.00.00.2-0.2-0.20.1-0.20.20.1-0.1-0.8
Fecal boli incidents, locomotor time 12.12.32.51.61.61.61.61.6-1.4-1.4-1.4-1.61.51.6-1.61.6-1.6-1.61.41.4
Change in fecal boli incidents, locomotor task1.51.41.7-1.1-1.2-1.2-1.2-1.21.21.21.21.2-1.2-1.21.3-1.31.21.3-1.0-0.8
Time >=10cm from walls, locomotor time 10.10.10.3-0.2-0.3-0.3-0.3-0.30.20.20.20.3-0.3-0.30.4-0.40.40.4-0.40.6
Bouts of movement, locomotor time 10.00.00.0-0.0-0.1-0.1-0.1-0.10.10.10.10.1-0.1-0.10.1-0.1-0.10.20.0-0.1
Total resting periods, locomotor time 10.20.20.30.50.50.40.40.4-0.5-0.5-0.5-0.40.40.4-0.40.4-0.6-0.30.50.6
Rest time, locomotor task time 10.40.50.70.70.70.70.70.6-0.8-0.8-0.8-0.70.60.6-0.60.7-0.7-0.50.50.9
Distance moved, locomotor task time 10.00.00.1-0.1-0.2-0.2-0.2-0.20.20.20.20.2-0.2-0.20.2-0.20.30.2-0.10.1
Vertical activity count, locomotor time 11.41.41.9-1.2-1.2-1.2-1.2-1.11.41.41.41.2-1.2-1.21.2-1.21.21.1-1.2-0.9
Time >=10cm from walls, locomotor time 20.60.60.80.80.80.80.80.8-0.6-0.6-0.6-0.80.80.8-0.80.8-0.8-0.90.80.6
Bouts of movement, locomotor time 22.83.03.4-1.8-1.8-1.8-1.8-1.71.81.81.81.7-1.7-1.71.7-1.71.61.6-1.8-1.7
Total resting periods, locomotor time 23.23.43.7-1.9-1.9-1.9-1.9-1.91.81.81.81.8-1.8-1.81.8-1.81.71.7-1.9-1.8
Rest time, locomotor task time 20.00.00.20.1-0.0-0.0-0.0-0.1-0.0-0.0-0.00.0-0.1-0.10.1-0.10.10.1-0.20.5
Distance moved, locomotor task time 20.00.10.20.20.20.20.20.2-0.2-0.2-0.2-0.20.20.2-0.20.2-0.2-0.20.40.2
Vertical activity count, locomotor time 20.00.00.2-0.2-0.1-0.1-0.1-0.00.00.00.00.1-0.1-0.10.1-0.10.1-0.0-0.2-0.4
Light reinforcement 12.85.05.52.22.32.32.32.3-2.2-2.2-2.2-2.32.32.3-2.32.3-2.3-2.32.31.5
Light reinforcement 20.71.01.40.91.01.01.01.0-0.7-0.7-0.7-1.11.11.1-1.11.1-1.2-1.11.10.0
Bone: marrow area7.917.117.9-4.2-4.2-4.2-4.2-4.24.24.24.24.2-4.2-4.24.2-4.24.24.1-3.9-3.7
Bone: maximum diameter3.36.08.6-2.5-2.5-2.5-2.5-2.42.32.32.32.6-2.6-2.62.5-2.62.52.4-2.9-1.5
Bone: maximum force15.626.928.6-5.3-5.2-5.2-5.2-5.35.35.35.35.2-5.2-5.25.2-5.25.15.1-4.8-4.8
Bone: maximum moment16.628.530.6-5.5-5.4-5.4-5.4-5.45.55.55.55.3-5.3-5.35.3-5.35.35.3-4.8-5.1
Mean time between licks in bursts0.00.00.20.20.20.20.20.2-0.1-0.1-0.1-0.20.20.2-0.20.1-0.1-0.10.50.1
Mean num. licks in bursts0.10.11.0-0.4-0.3-0.3-0.3-0.30.50.50.50.2-0.2-0.20.2-0.20.10.30.2-1.0
Cd content in liver0.80.91.00.90.90.90.90.9-1.0-1.0-1.0-0.90.90.9-0.90.9-0.9-1.00.80.7
Co content in liver0.80.91.20.90.90.90.91.0-1.0-1.0-1.0-0.90.90.9-1.01.1-1.1-1.10.30.7
Cu content in liver0.50.60.9-0.8-0.8-0.8-0.8-0.80.80.80.80.8-0.8-0.80.8-0.70.70.9-0.7-0.4
Fe content in liver0.50.61.10.80.80.80.80.8-0.8-0.8-0.8-0.70.70.7-0.70.8-0.8-0.70.51.1
K content in liver0.10.10.4-0.3-0.4-0.3-0.3-0.40.20.20.20.4-0.4-0.40.4-0.40.30.4-0.60.3
Mg content in liver0.10.10.20.20.20.20.20.2-0.3-0.3-0.3-0.10.10.1-0.20.1-0.1-0.2-0.20.5
Mn content in liver0.10.10.2-0.3-0.3-0.3-0.3-0.40.40.40.40.3-0.3-0.30.3-0.40.40.4-0.2-0.3
Na content in liver0.10.10.30.30.30.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.3-0.3-0.20.20.5
Rb content in liver0.70.92.81.00.90.90.90.9-1.1-1.1-1.1-0.80.80.8-0.80.8-0.8-0.80.51.7
Se content in liver0.91.12.51.11.01.01.01.1-1.3-1.3-1.3-1.01.01.0-0.90.9-0.9-1.00.71.6
Sr content in liver0.20.20.5-0.4-0.4-0.4-0.4-0.30.20.20.20.5-0.5-0.40.4-0.50.50.3-0.7-0.1
Zn content in liver2.42.63.21.71.61.61.61.6-1.8-1.8-1.8-1.61.61.6-1.61.6-1.6-1.61.21.8
Bone: minimum diameter9.317.318.4-4.3-4.2-4.2-4.2-4.24.24.24.24.2-4.2-4.24.1-4.24.14.1-4.0-3.8
Time in familiar zone, hab. session 10.20.20.30.40.40.40.50.4-0.4-0.4-0.4-0.50.50.5-0.50.6-0.5-0.40.6-0.1
Time in novel zone, hab. session 10.20.20.3-0.4-0.5-0.5-0.5-0.50.40.40.40.5-0.5-0.50.5-0.50.50.5-0.6-0.1
Total zone transitions, hab. session 10.30.40.50.60.70.70.70.6-0.6-0.6-0.6-0.70.70.7-0.70.7-0.7-0.60.70.3
Total locomotion distance, hab. session 10.00.00.50.1-0.0-0.0-0.0-0.0-0.0-0.0-0.00.0-0.0-0.10.1-0.20.20.10.10.7
Locomotion velocity, hab. session 10.00.00.30.0-0.1-0.1-0.1-0.10.10.10.10.1-0.1-0.10.2-0.30.30.20.00.5
Time in familiar zone, hab. session 20.50.51.6-0.8-0.7-0.7-0.7-0.70.80.80.80.7-0.7-0.70.6-0.60.60.6-0.5-1.3
Time in novel zone, hab. session 20.50.51.90.80.60.60.60.6-0.7-0.7-0.7-0.60.60.6-0.50.5-0.5-0.50.61.4
Total zone transitions, hab. session 20.30.40.40.60.60.60.60.6-0.6-0.6-0.6-0.60.60.6-0.60.6-0.6-0.60.60.4
Total locomotion distance, hab. session 20.10.10.40.40.30.30.30.3-0.4-0.4-0.4-0.30.30.3-0.30.1-0.1-0.30.50.7
Locomotion velocity, hab. session 20.00.00.20.30.20.20.20.2-0.2-0.2-0.2-0.20.20.2-0.1-0.00.1-0.20.30.5
Novel to familiar place preference ratio1.71.81.9-1.4-1.4-1.4-1.4-1.41.31.31.31.4-1.4-1.41.4-1.31.31.4-1.3-1.1
Novelty place preference1.21.21.4-1.1-1.1-1.1-1.1-1.11.11.11.11.1-1.1-1.11.2-1.11.11.2-1.1-0.8
Time in novel zone, NPP test1.01.01.2-1.0-1.0-1.0-1.0-1.01.01.01.01.0-1.0-1.01.0-1.01.01.1-1.0-0.6
Total zone transitions, NPP test1.52.13.71.61.51.51.51.5-1.5-1.5-1.5-1.41.41.4-1.41.4-1.4-1.31.31.9
Total locomotion distance, NPP test1.92.64.41.81.61.61.61.6-1.7-1.7-1.7-1.61.61.6-1.51.4-1.3-1.51.72.1
Locomotion velocity, NPP test1.11.52.91.41.21.21.21.2-1.3-1.3-1.3-1.21.21.2-1.11.0-1.0-1.11.21.7
Intraocular pressure7.610.511.03.33.33.33.33.3-3.2-3.2-3.2-3.33.33.3-3.33.3-3.3-3.33.22.6
Delta distance traveled before/after self-admin0.10.10.1-0.3-0.3-0.3-0.3-0.30.00.00.00.3-0.3-0.30.3-0.40.30.4-0.3-0.4
Delta ambulatory time before/after self-admin0.00.00.1-0.1-0.1-0.1-0.1-0.1-0.3-0.3-0.30.1-0.1-0.10.0-0.10.00.0-0.1-0.3
Parametrial fat weight2.24.35.02.02.12.12.12.1-2.2-2.2-2.2-2.12.12.1-2.12.1-2.1-2.01.91.5
Pavlov. Cond. lever latency0.10.20.5-0.2-0.3-0.3-0.4-0.40.40.40.40.3-0.3-0.40.5-0.40.40.70.10.5
Pavlov. Cond. magazine entry latency0.10.11.1-0.3-0.2-0.2-0.1-0.20.30.30.30.1-0.1-0.10.1-0.10.00.00.0-1.1
Pavlov. Cond. change in total contacts0.10.11.3-0.4-0.2-0.2-0.2-0.10.20.20.20.1-0.1-0.10.0-0.00.0-0.1-0.4-1.1
Pavlov. Cond. index score0.10.11.0-0.3-0.1-0.1-0.1-0.10.10.10.10.1-0.1-0.1-0.0-0.00.0-0.2-0.4-1.0
Pavlov. Cond. latency score0.10.10.8-0.2-0.0-0.0-0.00.0-0.1-0.1-0.10.0-0.00.0-0.10.0-0.0-0.3-0.4-0.9
Pavlov. Cond. lever contacts0.50.61.10.50.70.80.80.8-0.8-0.8-0.8-0.70.70.8-0.90.9-0.9-1.00.3-0.4
Pavlov. Cond. magazine entry number0.00.00.3-0.0-0.1-0.1-0.1-0.10.10.10.10.1-0.1-0.20.2-0.20.20.3-0.10.6
Pavlov. Cond. intertrial magazine entries0.70.95.41.00.80.80.80.8-0.9-0.9-0.9-0.70.70.7-0.60.6-0.6-0.50.62.3
Pavlov. Cond. lever-magazine prob. diff.0.20.31.5-0.6-0.4-0.4-0.4-0.40.40.40.40.4-0.4-0.40.3-0.30.30.2-0.7-1.2
Pavlov. Cond. response bias0.10.10.30.10.20.30.30.3-0.2-0.2-0.2-0.30.30.3-0.30.3-0.3-0.40.2-0.6
Pavlov. Cond. lever latency0.10.10.9-0.4-0.2-0.3-0.2-0.30.40.40.40.2-0.2-0.20.2-0.20.10.2-0.1-0.9
Pavlov. Cond. magazine entry latency0.91.01.3-0.8-1.0-1.0-1.0-1.00.80.80.81.1-1.1-1.11.1-1.11.11.2-1.10.3
Pavlov. Cond. change in total contacts1.21.62.8-1.3-1.3-1.3-1.3-1.31.11.11.11.3-1.3-1.31.3-1.31.31.2-1.7-0.8
Pavlov. Cond. index score0.30.40.7-0.5-0.6-0.6-0.6-0.60.40.40.40.7-0.7-0.70.8-0.70.80.7-0.90.6
Pavlov. Cond. latency score0.40.50.8-0.5-0.7-0.7-0.7-0.60.40.40.40.7-0.7-0.70.8-0.80.80.8-0.90.6
Pavlov. Cond. lever contacts0.20.30.90.60.50.50.50.5-0.7-0.7-0.7-0.50.50.5-0.50.5-0.4-0.50.40.9
Pavlov. Cond. magazine entry number1.72.12.81.31.51.51.51.5-1.2-1.2-1.2-1.51.61.6-1.61.6-1.6-1.61.7-0.0
Pavlov. Cond. intertrial magazine entries4.96.47.22.52.62.62.62.6-2.5-2.5-2.5-2.62.62.6-2.72.6-2.6-2.72.51.5
Pavlov. Cond. lever-magazine prob. diff.0.60.81.3-0.8-0.9-0.9-0.9-0.90.70.70.71.0-1.0-1.01.0-1.01.01.0-1.10.3
Pavlov. Cond. response bias0.00.10.40.20.20.20.20.2-0.3-0.3-0.3-0.10.10.1-0.10.1-0.1-0.10.00.7
Time in closed arm before self-admin1.31.51.8-1.3-1.3-1.3-1.3-1.31.01.01.01.3-1.3-1.31.3-1.31.21.3-1.2-1.1
Time in closed arm after self-admin0.60.70.8-0.9-0.9-0.9-0.9-0.90.40.40.40.9-0.9-0.90.9-0.90.90.8-0.8-0.8
Time in open arm before self-admin0.70.71.1-0.8-0.8-0.8-0.8-0.81.01.01.00.9-0.9-0.90.9-0.80.90.8-0.8-0.3
Time in open arm after self-admin0.20.20.30.50.50.50.50.5-0.1-0.1-0.1-0.50.50.5-0.50.6-0.6-0.50.50.5
Bone: periosteal estimation11.924.625.8-5.1-5.1-5.0-5.0-5.04.94.94.95.1-5.1-5.05.0-5.05.04.8-5.0-4.2
Bone: periosteal perimeter10.317.218.4-4.3-4.2-4.2-4.2-4.24.14.14.14.2-4.2-4.24.1-4.24.14.0-4.2-3.7
Bone: post-yield work9.312.713.7-3.6-3.6-3.6-3.6-3.63.73.73.73.6-3.6-3.63.6-3.63.53.6-3.2-3.2
Progressive ratio test 1 active lever presses5.75.99.32.62.42.42.42.5-2.4-2.4-2.4-2.42.42.4-2.32.3-2.4-2.42.13.1
Progressive ratio test 1 breakpoint5.15.37.92.52.32.32.32.4-2.2-2.2-2.2-2.32.32.3-2.22.2-2.3-2.32.02.8
Progressive ratio test 1 inactive lever presses3.53.84.72.02.02.02.02.0-1.8-1.8-1.8-2.02.02.0-2.02.1-2.2-1.91.91.4
Progressive ratio test 2 active lever presses2.62.83.41.81.71.71.71.7-1.6-1.6-1.6-1.71.71.7-1.71.6-1.8-1.81.51.5
Progressive ratio test 2 breakpoint3.33.74.32.02.02.02.02.0-1.8-1.8-1.8-2.02.02.0-2.01.9-2.0-2.11.81.6
Progressive ratio test 2 inactive lever presses2.63.03.61.71.81.81.81.8-1.8-1.8-1.8-1.81.81.8-1.81.7-1.9-1.81.71.1
Incentive Sensitization - Responses0.00.00.2-0.1-0.1-0.1-0.1-0.00.30.30.30.1-0.1-0.00.0-0.2-0.1-0.1-0.3-0.4
Incentive Sensitization - Breakpoint0.00.00.1-0.00.10.10.10.10.10.10.1-0.10.10.1-0.1-0.1-0.2-0.2-0.1-0.3
Sum of active levers in priming session hrs 5-60.10.10.50.30.20.20.20.2-0.5-0.5-0.5-0.20.20.2-0.10.2-0.2-0.00.30.7
Progressive ratio0.10.11.10.40.30.30.30.3-0.3-0.3-0.3-0.30.30.3-0.20.2-0.2-0.40.01.0
Food seeking constrained by brief footshock0.50.62.10.90.80.80.80.8-0.4-0.4-0.4-0.70.70.7-0.70.7-0.8-0.70.61.4
Seeking ratio, punishment vs. effort0.00.00.1-0.00.00.00.00.00.20.20.2-0.10.10.0-0.10.1-0.10.10.2-0.3
Retroperitoneal fat weight0.72.13.01.51.41.41.41.4-1.7-1.7-1.7-1.41.41.4-1.41.4-1.3-1.41.01.6
Reaction time number correct1.72.42.8-1.5-1.6-1.6-1.6-1.61.61.61.61.6-1.5-1.61.6-1.71.71.6-1.1-1.3
Reaction time mean minus median8.511.312.33.43.43.43.43.4-3.5-3.5-3.5-3.43.43.4-3.43.4-3.4-3.43.22.7
Reaction time mean minus median AUC6.17.98.42.92.82.82.82.8-2.9-2.9-2.9-2.82.82.8-2.82.8-2.8-2.72.82.3
Reaction time num false alarms1.72.32.71.61.51.51.51.5-1.6-1.6-1.6-1.51.51.5-1.51.5-1.4-1.51.41.4
Reaction time num false alarms AUC2.33.23.41.81.81.81.81.8-1.8-1.8-1.8-1.81.81.8-1.81.8-1.7-1.81.71.5
Reaction time trials correct on left1.72.42.8-1.5-1.6-1.6-1.6-1.61.61.61.61.6-1.5-1.61.6-1.71.71.6-1.1-1.3
Reaction time trials on left1.31.92.3-1.4-1.4-1.4-1.4-1.41.41.41.41.4-1.4-1.41.4-1.51.51.4-0.9-1.2
Reaction time mean0.81.01.31.11.01.01.01.1-1.1-1.1-1.1-1.01.01.0-1.01.0-1.0-1.00.71.1
Reaction time mean AUC0.40.60.80.80.80.80.80.8-0.8-0.8-0.8-0.80.70.8-0.80.7-0.7-0.80.50.9
Median of all reaction times0.00.00.10.0-0.0-0.0-0.0-0.0-0.0-0.0-0.00.0-0.1-0.00.0-0.10.10.0-0.30.3
Reaction time omissions10.013.614.33.83.83.83.83.8-3.7-3.7-3.7-3.73.73.7-3.73.7-3.7-3.73.73.2
Reaction time false alarm rate2.83.94.22.02.02.02.02.0-2.1-2.1-2.1-2.02.02.0-2.02.0-2.0-2.01.71.7
Reaction time premature initiation rate6.68.810.13.03.03.13.13.1-2.9-2.9-2.9-3.03.03.1-3.13.1-3.2-3.12.72.1
Reaction time premature initiations2.94.04.52.02.12.12.12.1-1.9-1.9-1.9-2.12.12.1-2.12.1-2.1-2.12.01.2
Std. dev. reaction times6.49.09.53.13.03.03.03.0-3.1-3.1-3.1-3.03.03.0-3.03.0-3.0-2.92.82.7
Reaction time trials completed1.31.92.3-1.4-1.4-1.4-1.4-1.41.41.41.41.4-1.4-1.41.4-1.51.51.4-0.9-1.2
Reaction time trials AUC2.13.03.5-1.7-1.7-1.8-1.8-1.81.81.81.81.7-1.7-1.71.8-1.91.91.8-1.2-1.5
Run reversals in cocaine runway, females0.10.11.1-0.3-0.1-0.1-0.1-0.10.30.30.30.1-0.1-0.10.00.1-0.10.10.0-1.0
Run reversals in cocaine runway, males1.61.51.91.21.21.21.21.2-1.4-1.4-1.4-1.21.21.2-1.21.2-1.2-1.21.10.8
Latency to leave start box in cocaine runway0.00.00.00.10.10.10.10.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.1-0.2-0.0-0.0
Latency to leave start box in cocaine runway, F1.81.92.21.41.41.41.41.4-1.3-1.3-1.3-1.41.41.4-1.41.3-1.3-1.51.41.2
Latency to leave start box in cocaine runway, M2.12.12.5-1.5-1.5-1.5-1.5-1.41.31.31.31.5-1.5-1.51.4-1.41.41.4-1.6-1.5
Std. dev. time between licks in bursts1.31.51.71.31.21.21.21.3-1.3-1.3-1.3-1.21.21.2-1.21.1-1.1-1.31.01.3
Total sessions with >9 infusions1.31.42.01.21.21.21.21.3-1.2-1.2-1.2-1.21.11.2-1.21.0-1.3-1.40.81.3
Short access day 1 total inactive lever presses1.71.92.21.41.41.41.41.4-1.5-1.5-1.5-1.41.41.4-1.41.4-1.4-1.41.21.1
Short access day 10 total inactive lever presses0.10.20.40.30.40.40.40.3-0.4-0.4-0.4-0.40.40.4-0.40.5-0.4-0.20.6-0.3
Short access day 1 total infusions0.10.10.60.40.40.40.40.4-0.2-0.2-0.2-0.40.30.4-0.30.3-0.4-0.50.10.8
Short access day 10 total infusions1.51.63.31.31.21.31.21.3-1.4-1.4-1.4-1.21.21.2-1.21.1-1.3-1.30.91.8
Short access total infusions0.80.91.61.01.01.01.01.0-0.9-0.9-0.9-0.90.90.9-0.90.8-1.0-1.10.61.3
Short access day 1 locomotion0.20.20.30.40.40.40.40.4-0.5-0.5-0.5-0.40.40.4-0.40.4-0.5-0.50.30.5
Short access day 10 total locomotion0.20.20.50.40.40.40.40.4-0.7-0.7-0.7-0.40.40.4-0.40.5-0.4-0.30.50.5
Short access total locomotion0.60.60.90.80.70.80.80.8-0.9-0.9-0.9-0.70.70.7-0.70.8-0.9-0.70.70.7
One hour access (0.3 mA shock)0.30.30.70.40.60.60.60.6-0.5-0.5-0.5-0.60.60.6-0.70.6-0.8-0.80.4-0.5
Compulsive drug intake1.31.42.6-1.2-1.1-1.1-1.1-1.21.21.21.21.1-1.1-1.11.1-1.01.21.1-1.1-1.6
One hour access (shock baseline)0.20.30.50.40.50.50.50.6-0.5-0.5-0.5-0.50.50.5-0.60.4-0.7-0.70.40.0
Social response proportion0.10.20.20.40.40.40.40.4-0.4-0.4-0.4-0.40.40.4-0.40.4-0.5-0.40.2-0.1
Social responses8.210.511.13.33.33.33.33.3-3.3-3.3-3.3-3.33.33.3-3.33.3-3.3-3.33.02.6
Social time0.00.10.5-0.2-0.1-0.1-0.1-0.10.30.30.30.0-0.0-0.00.00.1-0.20.10.1-0.7
Soleus weight0.72.02.8-1.5-1.4-1.4-1.4-1.41.41.41.41.4-1.4-1.41.4-1.31.31.4-1.4-1.7
Bone: stiffness18.328.931.1-5.6-5.4-5.4-5.4-5.45.55.55.55.4-5.4-5.45.3-5.45.35.2-5.1-5.3
Tibialis anterior weight1.13.711.0-2.2-1.8-1.8-1.8-1.82.02.02.01.8-1.8-1.71.6-1.41.41.4-2.2-3.3
Time to tail flick, vehicle, before self-admin0.80.81.10.90.90.90.90.9-0.7-0.7-0.7-0.90.90.9-0.91.0-0.9-0.91.00.7
Time to tail flick, vehicle, after self-admin0.30.31.1-0.6-0.6-0.6-0.6-0.60.50.50.50.5-0.5-0.50.5-0.50.50.5-0.3-1.1
Time to tail flick, test, before self-admin0.20.20.50.40.50.50.50.4-0.1-0.1-0.1-0.50.50.5-0.50.5-0.6-0.40.70.2
Time to tail flick, test, after self-admin0.30.30.8-0.6-0.5-0.5-0.5-0.50.80.80.80.5-0.5-0.50.5-0.50.40.5-0.4-0.9
Delta time to tail flick, vehicle, before/after SA0.40.40.9-0.7-0.7-0.7-0.7-0.70.40.40.40.6-0.6-0.60.6-0.70.60.7-0.6-1.0
Delta time to tail flick, test, before/after SA0.20.20.7-0.5-0.4-0.4-0.4-0.40.20.20.20.4-0.4-0.40.4-0.40.40.3-0.5-0.8
Tibia length7.019.624.1-4.5-4.5-4.5-4.5-4.54.24.24.24.6-4.6-4.54.5-4.64.54.3-4.9-3.2
Ambulatory time before self-admin4.24.34.92.22.12.12.12.1-2.0-2.0-2.0-2.12.12.1-2.02.1-2.0-1.92.12.2
Ambulatory time after self-admin2.32.53.61.61.51.51.51.5-1.9-1.9-1.9-1.51.51.5-1.51.4-1.4-1.41.41.6
Bone: tissue strength1.61.52.0-1.2-1.2-1.2-1.2-1.31.41.41.41.2-1.2-1.21.2-1.21.21.3-0.8-1.4
Total heroin consumption1.82.12.4-1.5-1.5-1.5-1.5-1.51.21.21.21.5-1.5-1.51.5-1.41.41.6-1.4-1.2
Bone: trabecular number6.610.311.9-3.2-3.3-3.3-3.3-3.33.23.23.23.3-3.3-3.33.3-3.43.43.2-2.9-2.4
Bone: trabecular spacing2.53.23.71.81.81.81.81.8-1.9-1.9-1.9-1.81.81.8-1.81.9-1.9-1.81.61.3
Bone: trabecular thickness0.10.10.70.10.20.20.20.2-0.1-0.1-0.1-0.30.30.3-0.30.3-0.3-0.40.4-0.8
Bone: trabecular tissue density0.10.11.2-0.00.10.10.20.2-0.1-0.1-0.1-0.20.20.2-0.30.2-0.2-0.30.4-1.1
Water consumed over 24 hours0.00.00.1-0.0-0.1-0.1-0.1-0.10.00.00.00.1-0.1-0.10.1-0.20.20.10.10.3
Number of responses in last shaping day0.10.10.4-0.2-0.1-0.1-0.1-0.10.40.40.40.1-0.1-0.10.0-0.10.0-0.00.0-0.6