Hub : Genes

Atat1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Atat1 0.03 0.03 2.9e-03 0.01 0.03 0.02 0.02 5.5e-02 7.8e-04 9.0e-04 2.3e-03
2 Brain isoform ratio XM_063279206.1 0.03 0.02 3.3e-03 0.01 0.02 0 0 4.3e-02 8.2e-03 1.2e-01 1.2e-01
3 NAcc intron excision ratio chr20_2856337_2858807 0.02 0.01 2.1e-03 0.02 0.01 0.01 0.02 5.2e-04 4.0e-03 2.4e-02 5.7e-04
4 Brain gene expression Atat1 0.31 0.15 0.0e+00 0.25 0.24 0.23 0.24 1.9e-23 3.8e-22 2.2e-21 2.0e-22
5 LHb gene expression Atat1 0.24 0.13 1.3e-04 0.16 0.12 0.09 0.11 1.3e-04 8.2e-04 3.3e-03 1.6e-03
6 pVTA intron excision ratio chr20_2856337_2858807 0.05 0.04 1.4e-03 0.02 0.02 0.02 0.03 6.2e-03 1.8e-02 6.2e-03 4.0e-03
7 pVTA isoform ratio XM_063279206.1 0.06 0.04 1.3e-04 0.03 0.02 0.04 0.03 1.3e-03 9.5e-03 5.5e-04 1.4e-03
8 Brain mRNA stability Atat1 0.06 0.04 1.4e-05 0.04 0.04 0.04 0.04 1.2e-04 6.6e-05 1.5e-04 7.3e-05
9 NAcc gene expression Atat1 0.17 0.07 0.0e+00 0.21 0.22 0.23 0.23 7.2e-31 7.1e-33 8.0e-34 5.4e-34
10 NAcc isoform ratio XM_063279206.1 0.03 0.02 1.6e-04 0.02 0.02 0.03 0.02 2.6e-04 1.9e-04 6.8e-05 2.8e-04
11 pVTA gene expression Atat1 0.42 0.13 0.0e+00 0.36 0.14 0.38 0.22 4.1e-30 2.8e-11 4.8e-32 5.4e-18
12 BLA gene expression Atat1 0.39 0.14 0.0e+00 0.31 0.3 0.29 0.32 4.0e-17 3.0e-16 8.5e-16 2.4e-17
13 IL gene expression Atat1 0.39 0.16 5.5e-07 0.22 0.22 0.23 0.23 6.4e-06 5.9e-06 3.6e-06 2.7e-06
14 OFC gene expression Atat1 0.15 0.1 7.4e-03 0.08 0.04 0.04 0.06 6.2e-03 4.0e-02 4.7e-02 1.3e-02
15 PL gene expression Atat1 0.2 0.07 0.0e+00 0.27 0.28 0.29 0.29 1.5e-29 3.7e-30 2.3e-31 1.9e-31
16 IC gene expression Atat1 0.21 0.09 2.5e-08 0.13 0.14 0.16 0.03 4.9e-06 2.3e-06 4.4e-07 1.9e-02
17 pVTA intron excision ratio chr20_2856337_2856451 0.05 0.04 2.2e-03 0.02 0 -0 -0 1.8e-02 1.5e-01 9.6e-01 5.0e-01
18 Adipose gene expression Atat1 0.08 0.06 1.6e-07 0.07 0.06 0.06 0.06 6.0e-08 6.4e-07 1.1e-07 2.9e-07
19 Liver mRNA stability Atat1 0.07 0.05 1.4e-05 0.01 0.02 0.05 0.02 9.0e-03 8.9e-04 7.8e-06 9.9e-04
20 Adipose isoform ratio NM_212498.1 0.03 0.03 8.7e-03 0.01 0.01 0.01 0 2.3e-02 3.5e-02 6.2e-02 1.1e-01
21 RMTg mRNA stability Atat1 0.11 0.08 8.8e-03 0.1 -0.01 -0.01 0.05 1.3e-03 9.4e-01 9.7e-01 2.3e-02
22 PL alternative polyA XM_063279206.1 0.03 0.03 1.0e-02 0.01 0 0.01 0 3.7e-02 1.1e-01 1.8e-02 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.91.53.71.90.10.80.80.81.50.81.41.40.80.90.81.90.81.10.8-0.81.71.81.61.70.6
Area under the delay curve1.41.62.7-0.7-1.1-1.3-1.3-1.2-1.4-1.1-1.5-1.5-1.5-1.5-1.1-1.3-1.5-1.5-1.31.1-1.6-0.3-0.3-1.4-0.6
BMI with tail1.55.38.20.4-2.9-2.5-2.5-2.5-2.2-2.7-2.1-2.2-2.7-2.5-2.8-2.2-2.7-2.4-2.42.6-2.00.31.2-1.6-2.8
BMI without tail3.19.513.5-0.7-3.2-3.7-3.7-3.6-3.3-3.4-3.3-3.4-3.6-3.5-3.6-2.8-3.3-3.4-3.53.5-2.6-0.20.6-2.3-2.9
Body weight5.122.333.8-4.1-3.1-5.0-4.9-4.9-5.8-4.8-5.8-5.6-4.9-4.6-4.7-5.1-4.4-5.0-4.34.6-5.6-3.8-0.5-4.9-4.6
Weight adjusted by age1.92.84.9-2.0-0.7-1.6-1.6-1.3-1.9-1.5-2.0-2.0-1.6-1.7-1.5-1.9-1.1-1.9-1.41.6-2.2-1.9-1.0-2.2-1.6
Bone surface0.10.10.7-0.80.3-0.1-0.1-0.1-0.4-0.0-0.4-0.40.2-0.1-0.1-0.1-0.1-0.1-0.10.10.1-0.4-0.70.10.4
Bone volume0.10.10.20.1-0.4-0.5-0.4-0.5-0.3-0.4-0.3-0.4-0.3-0.4-0.40.2-0.4-0.3-0.50.40.00.10.20.0-0.0
Breakpoint value in progressive ratio session0.40.41.50.20.70.60.70.60.70.80.70.70.50.70.90.60.90.60.5-0.90.3-0.0-0.30.21.2
Number of licking bursts0.60.93.8-0.81.30.80.80.80.61.10.60.61.00.91.1-0.31.00.90.9-1.10.5-0.4-2.00.51.6
Context. condit. distance diff. score7.99.614.2-0.23.63.43.43.42.93.72.92.93.63.43.62.83.53.53.4-3.52.80.2-1.52.83.8
Locomotion velocity, session 10.50.50.9-0.31.00.90.90.90.50.80.60.60.90.90.90.50.80.70.9-0.80.4-0.2-0.40.40.5
Locomotion distance, session 10.20.31.71.3-0.5-0.0-0.0-0.00.7-0.00.60.5-0.20.00.00.40.10.10.10.00.51.01.00.4-0.1
Locomotion velocity, session 20.10.10.6-0.40.40.40.40.40.10.30.10.10.30.30.3-0.00.30.20.3-0.3-0.2-0.6-0.8-0.30.1
Locomotion distance, session 20.10.20.50.70.20.40.40.40.70.40.60.60.20.40.40.60.50.40.5-0.40.20.30.30.10.0
Locomotion velocity, session 30.20.30.80.7-0.8-0.6-0.6-0.6-0.2-0.6-0.2-0.3-0.6-0.6-0.50.1-0.6-0.4-0.50.50.00.60.90.0-0.3
Locomotion distance, session 31.11.22.51.20.60.90.90.91.31.01.31.30.91.01.01.61.01.21.0-1.01.31.20.81.51.0
Stereotopy head waving bouts, day 31.11.33.9-2.00.1-0.7-0.7-0.7-1.4-0.6-1.4-1.3-0.7-0.8-0.6-1.8-0.7-0.9-0.70.6-1.6-2.0-1.3-1.7-0.3
Stereotopy head waving duration, day 30.91.12.7-1.5-0.1-0.8-0.8-0.8-1.2-0.7-1.2-1.2-0.7-0.8-0.6-1.7-0.7-0.9-0.70.6-1.4-1.6-0.9-1.5-0.4
Locomotion velocity, session 74.24.66.61.41.72.32.32.32.52.22.42.42.42.32.12.62.22.42.3-2.22.41.30.62.41.6
Locomotion distance, session 73.24.06.61.91.11.91.91.92.41.92.32.32.02.01.72.51.92.22.0-1.72.62.01.02.51.4
Stereotopy head waving bouts, day 72.62.94.7-1.5-1.0-1.6-1.6-1.6-2.0-1.7-2.0-1.9-1.6-1.6-1.7-2.1-1.7-1.9-1.71.7-2.0-1.8-0.3-2.2-1.5
Stereotopy head waving duration, day 72.53.05.0-1.5-1.1-1.7-1.7-1.7-2.0-1.7-2.0-2.0-1.6-1.7-1.7-2.1-1.6-1.9-1.71.7-2.1-1.8-0.2-2.2-1.5
Locomotion velocity, session 82.02.38.5-2.42.41.41.41.40.31.60.20.41.31.41.5-0.41.51.11.5-1.5-0.5-2.4-2.9-0.51.7
Locomotion distance, session 84.15.98.20.02.82.72.72.72.32.92.32.32.72.72.82.42.82.72.8-2.82.10.0-1.12.02.7
Degree of sensitization distance0.70.71.3-0.51.11.01.01.00.61.00.60.61.11.00.80.20.90.81.0-0.80.6-0.3-1.20.50.8
Degree of sensitization stereotypy1.21.31.9-0.7-0.9-1.1-1.1-1.1-1.3-1.2-1.3-1.2-1.1-1.2-1.3-1.4-1.2-1.3-1.21.3-1.3-1.0-0.1-1.4-1.1
Conditioned locomotion0.60.72.2-1.1-0.1-0.5-0.5-0.5-0.9-0.5-0.9-0.8-0.7-0.6-0.5-1.0-0.5-0.7-0.60.5-1.5-1.4-0.8-1.3-0.5
Cocaine response after cond. corrected0.40.51.00.70.40.60.60.61.00.70.90.80.50.60.80.70.70.70.7-0.80.70.7-0.50.91.0
Cocaine response after cond. not corrected0.20.32.2-0.90.50.20.20.2-0.10.3-0.2-0.20.10.20.3-0.50.20.10.2-0.3-0.5-0.9-1.5-0.20.6
Cocaine response before conditioning3.23.88.0-2.8-0.5-1.5-1.5-1.5-2.6-1.5-2.5-2.5-1.4-1.6-1.5-2.4-1.5-1.9-1.61.5-2.6-2.8-1.3-2.6-1.3
Saline control response2.33.04.90.5-2.2-1.9-1.9-1.9-1.7-2.2-1.6-1.6-1.8-1.9-2.0-0.9-2.1-1.8-2.02.0-1.10.41.9-0.9-2.1
Bone: connectivity density2.03.25.21.51.21.71.71.72.11.82.12.01.91.71.72.31.71.91.6-1.72.21.50.92.21.5
Bone: cortical apparent density0.81.12.51.1-1.6-1.1-1.1-1.1-0.5-1.3-0.5-0.6-1.3-1.1-1.1-0.1-1.1-1.1-1.11.2-0.60.51.6-0.7-1.3
Bone: cortical area1.42.13.1-1.2-1.0-1.5-1.5-1.5-1.8-1.5-1.8-1.8-1.4-1.5-1.5-1.6-1.5-1.6-1.31.4-1.7-1.2-0.4-1.6-1.3
Bone: cortical porosity0.60.60.9-0.4-0.7-0.8-0.8-0.8-0.9-0.8-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.70.9-1.0-0.1-0.4-0.7-0.4
Bone: cortical porosity0.40.41.1-1.0-0.2-0.5-0.4-0.5-0.8-0.4-0.8-0.8-0.5-0.6-0.6-1.1-0.5-0.6-0.40.5-0.9-0.5-1.0-0.7-0.2
Bone: cortical thickness4.06.610.30.6-3.2-3.0-2.9-3.0-2.3-3.2-2.3-2.4-3.0-2.9-3.0-1.8-3.0-2.9-2.82.9-2.1-0.11.7-2.0-2.8
Bone: cortical thickness2.02.46.21.3-2.3-1.5-1.6-1.5-0.9-1.9-0.9-1.0-1.5-1.6-1.8-0.8-1.8-1.6-1.61.7-0.70.52.5-0.6-2.1
Bone: cortical tissue density0.60.92.11.0-1.4-1.0-1.0-1.0-0.4-1.1-0.4-0.5-1.1-0.9-1.0-0.0-0.9-0.9-1.01.0-0.50.51.4-0.6-1.2
Condit. Reinf. active minus inactive responses0.70.71.40.50.70.90.90.91.00.91.01.00.80.90.91.20.90.91.1-0.80.70.30.20.70.6
Condit. Reinf. active-inactive response ratio0.10.10.30.4-0.5-0.2-0.2-0.2-0.2-0.5-0.1-0.0-0.4-0.3-0.4-0.2-0.4-0.3-0.20.4-0.20.20.2-0.2-0.6
Condit. Reinf. active responses1.11.43.31.00.81.21.21.21.41.11.41.31.11.21.21.81.11.21.1-1.21.20.70.81.20.6
Condit. Reinf. inactive responses1.82.25.61.90.41.11.11.11.81.21.71.61.21.21.32.41.21.41.0-1.41.91.71.91.90.7
Incentive salience index mean1.92.33.4-0.11.81.81.81.81.41.81.41.51.71.81.81.51.71.71.9-1.71.1-0.2-0.71.11.2
Condit. Reinf. lever presses3.65.18.1-0.42.82.62.62.62.02.72.02.22.72.62.62.02.62.62.6-2.51.8-0.2-1.21.82.0
Condit. Reinf. active minus inactive responses0.70.91.8-1.2-0.4-0.7-0.7-0.7-1.2-0.8-1.2-1.2-0.8-0.9-0.7-1.3-0.9-1.1-0.80.6-1.4-1.1-0.8-1.3-0.6
Condit. Reinf. active-inactive response ratio1.72.04.0-2.0-0.3-1.0-1.0-1.0-1.7-1.0-1.7-1.6-1.1-1.1-0.9-2.0-1.1-1.4-1.00.8-2.0-1.8-1.9-2.0-0.4
Condit. Reinf. active responses0.00.10.2-0.10.30.40.40.40.10.30.10.20.40.20.40.30.10.10.3-0.40.2-0.2-0.00.10.1
Condit. Reinf. inactive responses1.41.83.71.30.71.31.31.31.51.21.51.51.41.21.31.91.21.41.2-1.11.71.21.61.80.6
Condit. Reinf. lever presses0.60.91.40.50.81.01.01.01.11.01.01.11.21.01.10.90.91.01.1-1.01.10.50.21.00.6
Condit. Reinf. lever reinforcers received0.10.20.4-0.20.50.50.50.50.30.50.30.30.60.40.60.40.40.30.5-0.60.3-0.1-0.20.20.4
Conditioned reinforcement - actives1.01.84.10.0-1.4-1.8-1.8-1.8-1.2-1.1-1.2-1.1-1.6-1.7-1.5-1.0-2.0-1.4-1.51.5-1.2-0.00.1-1.1-0.6
Conditioned reinforcement - inactives1.32.03.30.2-1.6-1.8-1.8-1.8-1.2-1.1-1.3-1.4-1.8-1.7-1.4-1.0-1.6-1.6-1.81.4-1.60.30.2-1.5-1.0
Conditioned locomotion0.10.20.5-0.4-0.2-0.1-0.1-0.1-0.5-0.2-0.5-0.5-0.1-0.5-0.4-0.2-0.7-0.5-0.50.4-0.6-0.1-0.7-0.40.3
Patch foraging indifference point 0 sec0.71.33.11.2-1.7-1.4-1.5-1.5-0.4-1.1-0.6-0.7-1.5-1.4-1.1-0.7-0.8-1.0-1.21.1-0.40.91.8-0.1-0.9
Patch foraging indifference point AUC0.81.22.2-1.0-0.8-0.9-0.9-0.9-1.5-1.2-1.4-1.4-1.1-1.0-1.2-1.0-1.3-1.1-1.11.2-1.0-0.4-0.5-1.0-1.0
Delay disc. indifference point, 0s delay0.30.41.2-0.90.0-0.4-0.4-0.4-0.6-0.3-0.7-0.7-0.6-0.6-0.3-0.7-0.4-0.4-0.20.3-1.1-0.7-1.0-0.80.4
Delay disc. indifference point, 16s delay2.42.65.10.7-2.3-2.0-2.0-1.9-1.4-1.7-1.4-1.7-2.0-1.9-1.6-1.1-2.1-1.9-2.01.5-1.01.01.0-0.9-1.0
Delay disc. indifference point, 2s delay1.41.64.0-1.4-0.5-1.1-1.1-1.1-1.3-0.9-1.4-1.4-1.3-1.3-0.9-2.0-0.9-1.2-1.10.9-1.8-1.1-1.4-1.7-0.1
Delay disc. indifference point, 24s delay0.40.50.90.1-0.9-0.8-0.8-0.6-0.7-0.7-0.6-0.7-0.8-0.7-0.9-0.8-0.7-0.7-0.60.9-0.30.4-0.2-0.5-0.4
Delay disc. indifference point, 4s delay2.22.36.6-1.7-0.7-1.5-1.5-1.5-1.7-1.2-1.9-1.9-1.7-1.5-1.0-1.5-1.6-1.6-1.31.0-2.6-1.4-0.9-2.1-0.5
Delay disc. indifference point, 8s delay0.20.30.6-0.2-0.6-0.4-0.4-0.3-0.7-0.5-0.6-0.6-0.6-0.7-0.5-0.4-0.7-0.7-0.60.5-0.80.0-0.1-0.7-0.3
Indifference point function ln k0.30.51.1-0.41.00.90.80.90.50.80.60.80.90.80.70.00.70.91.1-0.70.4-0.4-0.80.30.7
Indifference point function log k0.30.51.1-0.41.00.90.80.90.50.80.60.80.90.80.70.00.70.91.1-0.70.4-0.4-0.80.30.7
Patch foraging total patch changes 0 sec0.91.84.11.2-2.0-1.6-1.7-1.7-0.6-1.4-0.8-0.9-1.7-1.6-1.4-0.9-1.1-1.3-1.51.4-0.51.01.8-0.2-1.2
Patch foraging total patch changes 12 sec1.31.73.80.9-2.0-1.5-1.4-1.4-0.8-1.5-1.0-1.0-1.6-1.6-1.5-1.0-1.3-1.2-1.41.4-0.61.11.2-0.4-1.4
Patch foraging total patch changes 18 sec1.11.75.82.1-2.1-1.4-1.3-1.3-0.1-1.2-0.2-0.4-1.4-1.1-1.10.1-1.1-0.7-1.11.10.22.02.40.6-1.4
Patch foraging total patch changes 24 sec0.81.37.52.6-1.6-0.5-0.5-0.60.8-0.50.50.5-0.7-0.5-0.60.8-0.3-0.2-0.70.50.92.32.71.0-0.5
Patch foraging total patch changes 6 sec1.42.15.11.6-2.3-1.6-1.6-1.6-0.6-1.5-0.7-0.8-1.8-1.5-1.5-0.9-1.2-1.3-1.71.5-0.41.62.0-0.2-1.7
Patch foraging time to switch 0 sec0.10.32.01.4-0.60.00.0-0.00.6-0.00.50.50.2-0.0-0.00.6-0.00.1-0.2-0.00.30.61.30.5-0.1
Patch foraging water rate 0 sec0.51.02.6-0.4-0.9-1.0-1.0-0.9-1.0-1.1-1.0-0.9-1.0-0.9-1.2-1.6-1.1-1.1-0.71.2-1.0-0.40.0-1.2-1.3
Patch foraging water rate 12 sec0.10.20.70.9-0.7-0.4-0.4-0.40.1-0.30.00.1-0.4-0.3-0.30.4-0.3-0.4-0.30.4-0.10.40.6-0.2-0.7
Patch foraging water rate 18 sec0.20.30.5-0.6-0.2-0.5-0.6-0.5-0.6-0.4-0.6-0.6-0.5-0.3-0.4-0.1-0.4-0.7-0.50.4-0.7-0.60.3-0.7-0.5
Patch foraging water rate 24 sec1.62.23.9-0.7-1.4-1.4-1.4-1.3-1.7-1.8-1.6-1.5-1.3-1.2-1.9-1.4-1.8-1.6-1.31.9-1.3-0.90.1-1.5-2.0
Patch foraging water rate 6 sec0.20.30.80.7-0.9-0.6-0.6-0.5-0.2-0.6-0.2-0.1-0.6-0.4-0.6-0.2-0.8-0.5-0.40.70.10.90.5-0.1-0.9
Seeking ratio, delayed vs. immediate footshock0.40.52.1-0.7-0.3-0.7-0.6-0.4-0.9-0.6-0.7-0.7-0.5-0.5-0.3-0.4-0.5-0.7-0.90.5-1.1-1.4-0.2-0.9-0.4
Distance traveled before self-admin0.20.21.3-1.10.80.50.50.4-0.40.4-0.3-0.20.2-0.00.30.20.50.0-0.2-0.2-0.6-0.9-0.7-0.40.3
Distance traveled after self-admin0.60.82.3-1.50.0-0.8-0.8-1.0-1.1-0.5-1.1-1.2-0.7-0.7-0.5-1.1-0.0-0.7-1.10.6-1.1-1.3-0.7-0.70.2
Extensor digitorum longus weight0.10.21.2-0.90.80.30.30.3-0.10.5-0.1-0.10.50.30.40.20.40.40.5-0.50.5-0.0-1.10.60.5
Bone: elastic displacement0.60.71.30.5-1.1-1.0-0.9-1.0-0.5-0.9-0.5-0.5-1.1-0.8-0.9-0.6-0.8-0.8-0.90.9-0.60.41.1-0.3-0.9
Bone: elastic work2.43.14.4-0.6-1.6-2.0-1.9-2.0-1.8-1.9-1.8-1.8-2.1-1.9-1.9-2.0-1.8-1.9-1.81.9-1.8-0.60.3-1.7-1.9
Bone: endosteal estimation1.32.917.9-4.21.7-0.1-0.0-0.1-1.80.2-1.8-1.60.1-0.1-0.1-2.1-0.0-0.5-0.1-0.0-1.8-3.2-3.7-1.90.3
Bone: endosteal perimeter1.32.810.5-2.92.81.61.61.60.11.80.20.31.71.51.6-0.31.61.31.6-1.70.0-1.9-3.20.11.6
Epididymis fat weight4.214.338.54.7-6.2-4.1-4.1-4.1-1.6-4.5-1.7-2.1-4.1-4.0-4.1-1.5-4.2-3.5-3.93.9-1.42.85.6-1.3-4.2
Delta time in closed arm before/after self-admin0.50.41.2-0.3-0.6-0.6-0.6-0.6-0.7-0.7-0.6-0.7-0.6-0.7-0.7-1.1-0.6-0.7-0.90.7-0.5-0.2-0.2-0.7-0.7
Delta time in open arm before/after self-admin0.20.21.1-0.4-0.2-0.1-0.2-0.3-0.5-0.1-0.5-0.5-0.4-0.5-0.40.1-0.5-0.3-0.20.5-1.0-0.60.7-0.8-0.3
Diff in mean of infusions in LGA sessions3.54.27.32.11.22.01.92.02.72.22.52.41.91.82.12.31.92.11.8-2.12.21.8-0.21.82.7
Delay discount exponential model param1.51.62.80.71.11.31.31.21.41.11.51.51.61.51.21.31.51.51.3-1.11.70.30.41.50.7
Extinction: sum of active levers before priming0.50.63.00.30.70.30.40.41.00.90.90.90.40.70.90.30.90.70.6-0.90.70.7-0.80.41.7
Active lever presses in extinction session 60.30.31.81.1-0.6-0.2-0.1-0.20.3-0.10.30.1-0.3-0.20.00.30.1-0.0-0.2-0.00.81.31.10.60.0
Bone: final force5.48.611.3-1.0-2.9-3.3-3.2-3.3-3.2-3.4-3.2-3.3-3.0-3.3-3.3-3.1-3.2-3.3-3.23.2-2.6-1.20.4-2.7-2.9
Bone: final moment4.77.59.8-1.0-2.7-3.0-3.0-3.0-3.0-3.1-3.0-3.1-2.8-3.1-3.1-2.8-3.0-3.1-2.93.0-2.5-1.20.3-2.5-2.7
Food consumed during 24 hour testing period0.40.52.2-1.50.3-0.2-0.2-0.2-1.0-0.3-0.9-0.8-0.1-0.2-0.4-0.6-0.4-0.4-0.20.3-1.0-1.5-0.6-1.1-0.6
Glucose3.14.911.2-2.33.42.52.52.51.12.51.11.32.52.42.41.12.42.12.6-2.40.4-2.2-3.10.52.4
Heart weight1.82.76.5-1.0-1.4-1.7-1.7-1.6-1.9-1.9-1.8-1.9-1.7-1.9-1.9-2.5-1.7-1.7-1.82.0-1.3-0.7-0.8-1.3-0.9
Delay discount hyperbolic model param1.61.73.20.81.11.31.31.31.51.21.51.51.61.51.21.51.51.51.4-1.11.80.40.51.60.7
Intermittent access intake day 1-15 change0.10.10.4-0.10.20.30.30.30.10.10.10.20.60.30.10.30.30.30.4-0.20.5-0.60.50.4-0.6
Intermittent access intake escalation0.10.21.50.1-0.3-0.2-0.3-0.2-0.2-0.4-0.3-0.30.1-0.2-0.20.3-0.1-0.2-0.10.20.2-0.61.20.2-1.0
Intermittent access intake escalation 20.30.42.3-1.10.80.60.60.7-0.00.2-0.1-0.10.90.50.40.30.50.30.5-0.50.3-1.50.00.2-0.7
Intermitt. access day 1 inactive lever presses0.20.64.7-1.50.6-0.3-0.3-0.4-0.40.2-0.6-0.6-0.10.0-0.2-1.10.2-0.5-0.10.2-0.8-0.9-2.2-1.1-0.1
Intermitt. access day 15 inactive lever presses0.61.32.4-1.1-0.7-1.1-1.1-1.1-1.2-1.0-1.4-1.5-1.0-1.0-1.3-1.4-1.2-1.2-1.11.3-0.9-0.7-0.5-1.0-1.5
Intermitt. access escalation Index2.43.45.00.91.81.81.81.82.02.22.12.21.72.01.91.91.82.12.2-2.11.61.5-0.11.61.9
Intermittent access day 1 total infusions0.30.42.11.2-0.5-0.7-0.6-0.60.40.30.50.4-0.7-0.40.00.6-0.20.1-0.0-0.00.01.50.80.21.4
Intermittent access day 15 total infusions0.20.31.80.8-0.7-0.9-0.9-0.8-0.1-0.3-0.1-0.1-0.7-0.6-0.40.5-0.6-0.3-0.30.3-0.30.31.3-0.00.2
Intermittent access terminal intake (last 3 days)0.50.61.50.6-1.0-1.2-1.2-1.1-0.5-0.6-0.5-0.6-1.0-1.0-0.8-0.2-1.0-0.7-0.80.7-0.60.20.8-0.5-0.2
Intermittent access total infusions0.30.41.00.6-0.8-1.0-1.0-0.9-0.3-0.3-0.3-0.3-0.9-0.8-0.50.1-0.8-0.5-0.50.5-0.40.60.8-0.20.4
Intermittent access day 1 locomotion0.20.21.80.40.2-0.0-0.00.00.30.50.40.4-0.20.10.30.9-0.00.30.2-0.4-0.10.60.70.31.3
Intermittent access day 15 total locomotion0.71.22.9-1.1-0.5-1.1-1.2-1.1-1.2-0.6-1.4-1.4-1.0-1.3-0.9-0.6-1.7-1.2-1.40.9-1.5-1.1-0.2-1.0-0.4
Intermittent access total locomotion0.81.02.0-0.8-0.5-1.2-1.3-1.1-1.1-0.6-1.2-1.2-1.1-1.1-0.9-0.3-1.4-1.1-1.00.8-1.4-0.70.2-0.9-0.1
Intermittent access standard deviation1.53.25.0-0.2-1.9-1.9-1.9-1.8-1.9-2.1-1.8-2.0-1.8-2.1-2.0-1.4-1.9-2.0-2.22.1-1.6-0.80.8-1.5-2.0
Left kidney weight3.918.328.0-2.8-3.4-4.1-4.2-4.0-5.3-4.8-5.0-4.9-4.4-4.4-4.6-4.5-4.7-4.6-4.44.5-4.7-2.70.3-4.0-4.5
Right kidney weight4.118.828.1-3.3-3.1-4.4-4.5-4.3-5.3-4.6-5.2-5.1-4.6-4.5-4.4-4.3-4.6-4.7-4.44.4-5.1-3.20.2-4.3-4.5
Cocaine induced anxiety0.71.01.9-0.51.41.11.11.10.81.20.81.01.11.21.20.71.41.11.3-1.20.60.1-0.60.61.0
Post-drug Anxiety0.70.71.7-0.10.81.01.01.00.70.70.80.90.90.90.90.41.30.91.1-0.80.90.4-0.60.80.6
Baseline Anxiety0.30.31.81.3-0.60.20.20.20.6-0.20.70.50.10.00.1-0.20.20.30.1-0.01.01.1-0.10.9-0.0
Tail length2.610.027.0-5.2-0.3-3.0-2.9-2.9-4.1-2.2-4.2-4.0-2.7-2.5-2.3-3.5-2.0-2.9-2.52.3-4.0-4.2-2.6-3.7-1.8
Length with tail3.715.941.7-6.5-0.4-3.6-3.5-3.5-5.2-3.0-5.3-5.0-3.1-3.0-2.9-4.3-2.7-3.6-2.82.9-5.2-5.8-2.8-4.7-2.7
Length without tail3.711.820.9-4.6-1.1-2.9-2.9-2.9-4.4-3.1-4.3-4.1-2.8-2.8-2.9-4.2-2.9-3.3-2.62.8-4.6-4.6-1.8-4.1-3.0
Times rat made contact with spout0.91.14.72.2-0.60.20.20.21.00.11.11.00.30.30.11.00.20.60.2-0.21.62.12.11.5-0.2
Lifetime Intake0.50.61.60.4-0.9-1.3-1.3-1.1-0.6-0.4-0.6-0.6-1.3-1.2-0.7-0.1-0.8-0.7-0.90.7-0.70.50.6-0.50.4
Liver weight, left0.81.38.0-2.81.80.50.50.5-0.60.7-0.7-0.50.30.50.5-0.60.50.20.5-0.6-1.1-2.4-2.1-0.80.7
Liver weight, right1.42.412.6-3.61.0-0.6-0.5-0.6-1.9-0.3-1.9-1.7-0.4-0.6-0.5-1.8-0.3-0.8-0.40.4-2.1-3.3-2.1-1.9-0.0
Locomotor activity0.81.28.0-2.81.30.70.70.8-1.10.1-1.0-0.70.80.30.2-1.00.20.00.2-0.2-1.2-2.6-1.5-0.5-0.6
Locomotor testing distance0.30.52.2-1.51.00.90.80.9-0.30.3-0.2-0.10.90.50.4-0.50.40.40.5-0.4-0.3-1.0-1.20.3-0.2
Locomotor testing rearing0.20.42.5-1.60.60.40.40.5-0.8-0.1-0.7-0.50.10.1-0.1-0.7-0.0-0.10.1-0.1-0.9-1.1-0.9-0.5-0.5
Locomotion in novel chamber0.60.72.3-0.6-0.6-0.8-0.9-0.9-1.1-0.7-1.1-1.1-1.0-1.1-0.8-0.6-1.5-1.0-1.10.7-0.70.10.5-0.4-0.4
Locomotion in novel chamber post-restriction0.91.53.2-0.3-1.2-1.3-1.3-1.5-1.0-1.3-1.2-1.3-1.3-1.5-1.2-1.3-1.3-1.5-1.51.0-1.2-0.60.1-1.2-1.8
Fecal boli incidents, locomotor time 10.50.72.40.80.50.30.30.30.70.71.00.90.70.80.81.00.90.90.5-0.91.10.40.71.11.6
Change in fecal boli incidents, locomotor task0.90.93.7-1.0-0.4-0.7-0.7-0.7-0.6-0.6-1.0-0.9-0.6-0.7-0.8-1.9-0.5-0.9-0.60.7-1.3-1.0-1.8-1.3-0.3
Time >=10cm from walls, locomotor time 10.60.73.2-1.60.5-0.4-0.4-0.5-0.60.1-0.7-0.6-0.2-0.2-0.4-1.4-0.2-0.3-0.30.2-0.9-1.8-1.7-1.00.2
Bouts of movement, locomotor time 11.11.23.0-0.11.31.51.51.50.61.00.91.11.31.31.21.00.81.41.7-1.20.70.1-0.21.10.5
Total resting periods, locomotor time 10.60.71.7-0.41.11.11.11.10.30.80.60.71.01.01.00.70.51.01.3-1.10.2-0.3-0.40.70.7
Rest time, locomotor task time 10.30.32.6-1.30.80.40.40.4-0.10.3-0.3-0.30.40.30.3-0.40.6-0.10.0-0.3-0.9-1.6-0.3-0.5-0.1
Distance moved, locomotor task time 10.60.92.00.2-1.1-1.4-1.4-1.4-0.8-1.1-0.8-0.7-1.2-1.0-1.1-0.9-1.1-0.9-1.11.2-0.10.2-0.0-0.6-0.7
Vertical activity count, locomotor time 10.20.51.50.2-0.9-0.9-0.9-0.9-0.8-1.0-0.6-0.4-0.8-0.7-0.9-0.7-0.8-0.7-0.61.0-0.10.30.3-0.4-1.2
Time >=10cm from walls, locomotor time 20.20.32.7-0.90.60.40.40.5-0.20.2-0.00.20.30.2-0.1-0.80.10.10.4-0.0-0.4-0.9-1.6-0.60.4
Bouts of movement, locomotor time 20.50.85.0-1.80.80.60.60.6-0.8-0.1-0.7-0.40.30.4-0.2-0.6-0.1-0.00.40.2-1.6-2.2-0.2-1.0-1.4
Total resting periods, locomotor time 20.50.95.3-2.01.31.01.01.0-0.60.3-0.4-0.20.60.70.1-0.40.20.30.7-0.2-1.5-2.3-0.4-0.9-1.1
Rest time, locomotor task time 21.41.85.1-1.92.31.71.71.60.51.40.50.61.71.51.30.21.11.21.4-1.4-0.2-2.0-1.20.20.5
Distance moved, locomotor task time 21.51.83.80.9-1.9-1.8-1.8-1.8-1.0-1.6-0.9-0.9-1.8-1.5-1.5-1.1-1.3-1.3-1.41.7-0.30.90.9-0.9-1.2
Vertical activity count, locomotor time 20.20.31.10.8-0.9-0.8-0.8-0.8-0.0-0.5-0.1-0.2-0.7-0.5-0.4-0.40.0-0.4-0.50.50.21.00.3-0.2-0.7
Light reinforcement 10.10.20.80.7-0.9-0.7-0.7-0.70.0-0.5-0.2-0.3-0.3-0.7-0.4-0.3-0.1-0.6-0.60.4-0.1-0.30.7-0.3-0.2
Light reinforcement 20.40.74.3-1.2-0.0-0.5-0.5-0.7-0.8-0.5-0.9-0.9-0.3-0.5-0.4-0.7-0.0-0.8-0.50.4-1.2-2.1-0.2-1.5-0.5
Bone: marrow area1.32.817.4-4.21.6-0.1-0.1-0.1-1.80.2-1.8-1.60.1-0.1-0.1-2.1-0.1-0.5-0.10.0-1.8-3.2-3.5-1.90.2
Bone: maximum diameter0.51.06.9-2.41.40.40.50.4-0.60.6-0.6-0.50.60.40.4-0.90.50.30.5-0.5-0.6-1.6-2.6-0.50.7
Bone: maximum force3.96.99.1-1.3-2.3-2.9-2.8-2.9-3.0-2.9-3.0-3.0-2.7-2.9-2.9-2.8-2.8-2.9-2.72.8-2.5-1.30.2-2.6-2.6
Bone: maximum moment3.45.98.1-1.4-2.1-2.6-2.6-2.6-2.8-2.7-2.8-2.8-2.5-2.6-2.6-2.6-2.6-2.7-2.52.6-2.4-1.3-0.0-2.4-2.3
Mean time between licks in bursts0.81.94.9-1.92.21.51.51.50.51.60.40.51.41.51.50.71.51.11.5-1.5-0.0-1.5-2.0-0.01.5
Mean num. licks in bursts0.71.17.11.8-1.5-0.6-0.6-0.6-0.0-1.0-0.0-0.1-0.8-0.6-0.90.7-0.8-0.5-0.70.90.31.52.70.3-1.6
Cd content in liver0.20.21.51.0-0.5-0.1-0.1-0.10.4-0.10.30.3-0.5-0.1-0.00.3-0.1-0.2-0.2-0.1-0.40.41.2-0.4-0.5
Co content in liver1.31.53.00.8-1.7-1.3-1.3-1.3-0.9-1.4-0.8-0.9-1.6-1.4-1.4-1.0-1.5-1.5-1.61.4-0.90.90.7-0.8-1.4
Cu content in liver1.51.86.32.5-0.30.60.60.61.50.61.51.50.60.60.72.10.70.90.6-0.71.92.51.92.00.5
Fe content in liver1.01.22.20.5-1.5-1.2-1.2-1.2-0.9-1.3-0.9-1.0-1.2-1.2-1.3-0.6-1.1-1.1-1.21.3-0.80.41.1-0.7-1.4
K content in liver0.20.21.30.7-0.30.10.10.10.2-0.10.30.20.40.1-0.10.3-0.20.1-0.10.11.10.90.41.2-0.0
Mg content in liver1.51.62.7-0.21.41.31.31.31.01.41.11.11.51.21.30.91.21.31.2-1.31.50.6-1.51.61.7
Mn content in liver3.84.27.8-1.22.82.32.32.31.42.41.51.72.62.32.31.32.32.12.3-2.21.6-0.4-2.41.82.2
Na content in liver0.80.81.90.8-1.4-0.9-0.9-0.9-0.7-1.2-0.6-0.7-0.9-1.0-1.1-0.5-1.1-0.9-1.21.20.01.10.60.1-0.8
Rb content in liver1.11.33.50.90.60.90.90.91.20.91.21.11.11.01.01.30.81.31.1-1.01.71.60.41.90.9
Se content in liver1.41.75.8-1.72.11.51.51.50.51.40.50.71.31.41.30.11.51.11.4-1.30.1-0.8-2.40.41.2
Sr content in liver0.40.31.1-1.10.1-0.4-0.4-0.4-0.7-0.3-0.7-0.6-0.2-0.4-0.3-0.9-0.4-0.6-0.40.4-0.8-0.9-0.8-0.6-0.2
Zn content in liver0.10.10.2-0.20.40.40.40.40.20.40.20.20.30.30.30.20.30.30.3-0.40.40.2-0.30.50.4
Bone: minimum diameter0.71.27.3-2.71.60.50.50.5-0.70.7-0.7-0.60.70.50.5-1.00.50.20.6-0.6-0.9-2.3-2.2-0.90.4
Time in familiar zone, hab. session 11.91.97.12.6-0.20.80.80.81.70.61.71.60.60.90.71.90.70.90.8-0.71.52.02.71.5-0.2
Time in novel zone, hab. session 11.01.04.4-2.10.5-0.4-0.4-0.4-1.2-0.2-1.2-1.1-0.2-0.4-0.3-1.4-0.3-0.5-0.40.3-1.0-1.7-2.1-1.00.4
Total zone transitions, hab. session 10.50.71.20.80.50.80.80.81.00.81.01.00.80.80.81.10.80.90.8-0.81.10.50.61.10.6
Total locomotion distance, hab. session 10.30.40.80.90.20.50.50.50.90.50.80.80.40.50.50.60.50.60.5-0.50.70.50.80.70.2
Locomotion velocity, hab. session 10.10.10.60.8-0.20.10.10.10.50.10.50.5-0.00.10.10.20.10.20.1-0.10.40.40.70.4-0.0
Time in familiar zone, hab. session 20.20.21.31.0-0.30.10.10.10.50.00.40.4-0.10.10.10.60.10.1-0.0-0.10.40.91.10.4-0.3
Time in novel zone, hab. session 20.20.20.4-0.6-0.1-0.3-0.3-0.3-0.6-0.4-0.5-0.6-0.2-0.4-0.4-0.5-0.4-0.4-0.30.4-0.4-0.6-0.4-0.40.0
Total zone transitions, hab. session 20.10.10.20.5-0.4-0.2-0.2-0.20.1-0.30.0-0.0-0.3-0.3-0.2-0.3-0.2-0.3-0.20.2-0.10.20.3-0.3-0.4
Total locomotion distance, hab. session 20.50.71.51.20.30.70.70.71.20.71.21.10.60.70.70.60.80.80.7-0.71.00.80.70.90.2
Locomotion velocity, hab. session 20.60.81.71.10.40.80.80.81.30.81.21.20.70.80.80.60.90.90.8-0.81.00.80.50.90.3
Novel to familiar place preference ratio0.10.10.20.4-0.5-0.4-0.4-0.4-0.1-0.3-0.1-0.1-0.1-0.4-0.3-0.1-0.3-0.2-0.40.30.30.40.10.30.1
Novelty place preference0.10.10.30.1-0.5-0.5-0.5-0.5-0.3-0.4-0.3-0.3-0.3-0.5-0.5-0.3-0.5-0.4-0.50.40.00.1-0.10.0-0.1
Time in novel zone, NPP test0.20.20.4-0.1-0.5-0.6-0.6-0.6-0.5-0.5-0.4-0.5-0.3-0.6-0.6-0.5-0.5-0.5-0.60.5-0.1-0.2-0.2-0.2-0.2
Total zone transitions, NPP test0.81.21.90.90.81.11.11.11.41.11.31.31.11.11.21.31.21.21.2-1.11.10.50.31.10.8
Total locomotion distance, NPP test0.60.81.91.40.20.70.70.71.20.71.21.20.50.70.71.00.70.90.7-0.71.11.00.81.10.5
Locomotion velocity, NPP test1.11.53.11.80.41.01.01.01.71.01.61.60.91.11.11.51.11.31.1-1.01.51.40.91.50.8
Intraocular pressure0.71.12.31.00.61.11.11.11.01.01.11.10.91.01.01.51.01.00.9-1.10.80.71.31.00.9
Delta distance traveled before/after self-admin1.71.83.4-0.7-1.2-1.8-1.8-1.8-1.3-1.4-1.5-1.6-1.5-1.4-1.3-1.8-1.1-1.4-1.51.3-1.2-0.7-0.2-1.0-0.4
Delta ambulatory time before/after self-admin1.01.33.5-0.9-0.8-1.4-1.4-1.3-1.1-1.1-1.3-1.4-1.2-1.0-1.1-1.9-0.9-1.1-1.10.9-1.3-0.9-0.4-1.1-0.3
Parametrial fat weight1.02.33.8-0.6-1.3-1.8-1.8-1.8-1.9-1.7-1.7-1.6-1.5-1.8-1.9-0.8-2.0-1.3-1.71.8-1.1-0.41.2-0.4-1.4
Pavlov. Cond. lever latency2.02.55.71.6-2.4-1.9-1.9-1.9-0.8-1.8-0.8-1.0-1.8-1.7-1.8-0.9-1.7-1.5-1.71.8-0.51.32.3-0.6-1.4
Pavlov. Cond. magazine entry latency2.53.26.4-1.12.52.12.12.11.32.21.31.42.02.12.21.22.11.92.1-2.20.9-0.7-1.40.91.6
Pavlov. Cond. change in total contacts0.50.53.1-1.80.90.30.30.3-0.60.3-0.5-0.50.20.20.3-0.50.20.00.2-0.3-0.6-1.6-1.6-0.6-0.0
Pavlov. Cond. index score3.03.78.0-1.52.82.32.32.31.32.31.31.42.22.22.31.22.22.02.2-2.30.8-1.1-2.10.81.7
Pavlov. Cond. latency score2.43.06.9-1.72.62.12.12.10.92.01.01.11.92.02.00.91.91.71.9-2.00.6-1.3-2.30.61.5
Pavlov. Cond. lever contacts1.82.15.1-1.72.31.71.71.70.61.60.70.81.61.61.60.51.51.31.6-1.60.3-1.4-2.20.41.2
Pavlov. Cond. magazine entry number3.03.76.30.6-2.5-2.3-2.3-2.3-1.7-2.3-1.7-1.8-2.2-2.3-2.3-1.4-2.3-2.1-2.32.3-1.30.41.2-1.3-1.6
Pavlov. Cond. intertrial magazine entries0.60.73.92.0-1.1-0.4-0.4-0.40.6-0.40.50.4-0.4-0.3-0.21.1-0.3-0.1-0.40.30.61.51.80.8-0.2
Pavlov. Cond. lever-magazine prob. diff.3.23.98.0-1.32.82.42.42.41.42.41.41.52.22.32.41.32.32.12.3-2.41.0-1.0-1.91.01.8
Pavlov. Cond. response bias3.34.17.9-1.12.82.42.42.41.52.41.51.72.42.42.41.42.32.22.4-2.41.1-0.9-1.61.11.8
Pavlov. Cond. lever latency0.20.30.7-0.8-0.1-0.4-0.4-0.4-0.7-0.3-0.7-0.7-0.3-0.4-0.5-0.6-0.3-0.4-0.50.4-0.6-0.6-0.8-0.50.1
Pavlov. Cond. magazine entry latency0.20.30.9-0.90.0-0.4-0.4-0.4-0.6-0.3-0.6-0.6-0.4-0.4-0.3-0.7-0.3-0.5-0.30.3-0.7-0.9-0.5-0.6-0.2
Pavlov. Cond. change in total contacts0.10.20.4-0.0-0.6-0.5-0.5-0.5-0.5-0.6-0.5-0.5-0.5-0.6-0.5-0.7-0.7-0.6-0.40.5-0.40.1-0.1-0.4-0.4
Pavlov. Cond. index score0.00.00.1-0.20.20.10.10.10.00.1-0.00.0-0.00.10.2-0.00.0-0.00.2-0.1-0.1-0.30.0-0.2-0.1
Pavlov. Cond. latency score0.00.00.1-0.1-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.1-0.3-0.2-0.3-0.10.2-0.3-0.20.1-0.3-0.3
Pavlov. Cond. lever contacts0.10.10.40.6-0.00.30.30.30.50.10.40.40.10.20.20.30.10.20.3-0.20.30.50.60.2-0.2
Pavlov. Cond. magazine entry number0.20.30.60.50.20.50.50.50.60.50.60.60.60.50.40.70.50.60.4-0.40.70.60.30.80.5
Pavlov. Cond. intertrial magazine entries1.62.33.7-0.31.91.61.61.61.31.91.31.41.71.71.81.61.81.71.7-1.81.1-0.0-0.91.21.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.10.20.10.10.10.10.10.10.10.00.10.30.00.10.00.2-0.2-0.1-0.20.1-0.10.0
Pavlov. Cond. response bias0.10.20.40.00.50.50.50.50.50.50.40.50.50.50.60.30.40.40.6-0.50.3-0.10.10.20.2
Time in closed arm before self-admin0.10.10.50.00.20.50.30.20.20.10.30.30.50.20.10.0-0.20.40.4-0.20.60.2-0.50.70.3
Time in closed arm after self-admin1.11.12.20.3-1.3-1.0-1.1-1.0-0.8-1.2-0.9-1.0-1.1-1.4-1.3-1.2-1.5-1.2-1.41.1-0.40.70.2-0.5-1.2
Time in open arm before self-admin0.60.61.2-0.10.90.80.91.00.81.00.70.70.71.01.00.70.70.70.9-1.00.7-0.0-0.40.41.1
Time in open arm after self-admin0.50.61.4-0.41.00.91.00.80.61.00.50.60.60.80.90.60.80.71.0-0.9-0.2-0.6-0.1-0.11.2
Bone: periosteal estimation1.32.810.7-3.30.4-1.0-0.9-1.0-2.2-0.8-2.1-2.0-0.8-1.0-1.0-2.3-0.9-1.3-0.90.9-2.2-2.7-2.5-2.2-0.7
Bone: periosteal perimeter0.50.95.5-2.30.9-0.1-0.0-0.1-1.00.1-1.0-0.9-0.1-0.1-0.1-1.1-0.0-0.30.0-0.0-1.1-1.7-2.2-1.00.1
Bone: post-yield work1.21.74.5-1.72.11.51.61.50.51.50.50.61.51.41.40.51.41.31.6-1.40.4-1.1-1.60.31.1
Progressive ratio test 1 active lever presses0.40.51.60.7-0.7-1.3-1.3-1.2-0.2-0.3-0.1-0.1-1.1-0.8-0.5-0.2-0.7-0.4-0.40.5-0.40.90.3-0.30.7
Progressive ratio test 1 breakpoint0.40.51.80.7-0.7-1.3-1.3-1.3-0.2-0.4-0.1-0.1-1.2-0.9-0.5-0.3-0.7-0.5-0.40.5-0.40.80.2-0.30.7
Progressive ratio test 1 inactive lever presses0.50.71.71.3-1.3-1.3-1.3-1.20.0-0.6-0.1-0.3-1.0-0.8-0.8-0.1-1.0-0.6-0.80.90.21.30.60.1-0.2
Progressive ratio test 2 active lever presses0.20.21.21.1-0.3-0.4-0.3-0.30.50.30.50.5-0.4-0.20.10.7-0.30.10.0-0.10.10.90.40.20.5
Progressive ratio test 2 breakpoint0.20.21.31.1-0.4-0.4-0.4-0.40.50.20.40.4-0.4-0.30.00.7-0.40.1-0.1-0.10.10.90.50.20.4
Progressive ratio test 2 inactive lever presses0.30.40.9-0.3-0.3-0.9-0.9-0.9-0.6-0.1-0.6-0.6-0.8-1.0-0.6-0.7-0.9-0.6-0.80.6-0.5-0.1-0.7-0.60.4
Incentive Sensitization - Responses0.30.41.10.80.40.50.60.51.10.90.90.80.60.70.80.80.50.80.4-0.70.60.3-0.00.60.4
Incentive Sensitization - Breakpoint0.40.51.10.80.40.50.60.61.00.90.90.80.60.70.71.00.50.80.4-0.70.60.40.10.60.3
Sum of active levers in priming session hrs 5-60.40.41.30.10.60.70.70.80.70.70.70.70.60.70.80.30.80.50.4-0.80.3-0.40.10.11.1
Progressive ratio4.67.39.7-1.1-2.4-2.8-2.8-3.1-3.0-2.7-2.9-2.9-3.0-3.0-2.9-2.8-2.8-2.9-3.13.1-2.7-1.31.3-2.6-2.5
Food seeking constrained by brief footshock0.10.10.50.3-0.00.30.30.1-0.1-0.00.20.20.20.10.00.3-0.20.3-0.00.00.60.70.60.70.1
Seeking ratio, punishment vs. effort4.15.98.31.12.02.72.72.92.62.32.72.72.82.82.42.32.32.62.7-2.62.71.5-1.32.62.3
Retroperitoneal fat weight0.41.62.5-0.5-1.2-1.5-1.5-1.6-1.4-1.4-1.5-1.4-1.2-1.5-1.4-0.8-1.5-1.2-1.21.3-1.4-1.00.9-0.8-1.2
Reaction time number correct0.51.02.51.2-1.6-0.9-1.0-1.0-0.4-1.2-0.4-0.5-0.9-0.9-1.3-0.5-1.3-0.9-1.11.30.01.01.5-0.2-1.4
Reaction time mean minus median0.92.37.0-2.42.61.61.61.70.31.70.30.61.31.71.71.31.61.21.8-1.8-0.6-2.3-1.0-0.00.7
Reaction time mean minus median AUC0.71.85.3-1.82.31.61.61.60.51.50.50.71.11.61.61.21.41.21.7-1.6-0.4-1.6-0.90.00.4
Reaction time num false alarms0.30.41.6-0.8-0.1-0.5-0.5-0.5-0.7-0.4-0.7-0.7-0.3-0.5-0.5-1.0-0.5-0.5-0.30.5-0.9-1.3-0.6-1.1-0.3
Reaction time num false alarms AUC0.50.71.8-1.0-0.2-0.8-0.8-0.7-0.9-0.6-0.9-0.9-0.5-0.8-0.7-1.3-0.7-0.7-0.50.7-1.0-1.3-1.1-1.3-0.2
Reaction time trials correct on left0.51.02.51.2-1.6-0.9-1.0-1.0-0.4-1.2-0.4-0.5-0.9-0.9-1.3-0.5-1.3-0.9-1.11.30.01.01.5-0.2-1.4
Reaction time trials on left0.51.02.31.1-1.5-0.9-0.9-1.0-0.5-1.2-0.5-0.5-0.9-0.9-1.3-0.5-1.3-0.9-1.01.3-0.10.91.4-0.3-1.4
Reaction time mean2.03.28.1-2.12.81.91.92.00.92.10.80.91.81.92.11.42.01.52.0-2.1-0.1-2.1-2.10.41.7
Reaction time mean AUC2.03.38.2-2.12.92.02.02.00.92.10.80.91.82.02.11.42.01.52.0-2.2-0.2-2.3-2.00.31.6
Median of all reaction times1.62.35.2-1.62.31.61.61.70.81.70.70.71.61.61.71.01.61.31.6-1.70.1-1.6-2.20.41.6
Reaction time omissions1.31.95.1-1.82.21.41.41.40.61.70.50.61.01.41.50.91.71.21.7-1.6-0.3-1.3-1.8-0.01.5
Reaction time false alarm rate0.50.63.5-1.60.8-0.1-0.1-0.0-0.50.2-0.5-0.50.1-0.10.2-0.90.2-0.10.2-0.2-0.9-1.8-1.9-1.00.7
Reaction time premature initiation rate1.41.93.0-0.7-1.2-1.6-1.6-1.6-1.7-1.6-1.5-1.4-1.2-1.6-1.7-1.7-1.5-1.5-1.61.6-1.1-0.7-0.4-1.1-1.1
Reaction time premature initiations1.93.45.6-0.1-2.1-2.1-2.1-2.2-1.9-2.3-1.8-1.7-1.8-2.1-2.4-2.0-2.2-2.0-2.12.3-1.1-0.00.4-1.3-1.9
Std. dev. reaction times1.32.47.3-2.72.71.51.51.60.21.60.20.41.11.51.70.81.61.11.7-1.7-1.0-2.5-2.0-0.41.2
Reaction time trials completed0.51.02.31.1-1.5-0.9-0.9-1.0-0.5-1.2-0.5-0.5-0.9-0.9-1.3-0.5-1.3-0.9-1.01.3-0.10.91.4-0.3-1.4
Reaction time trials AUC0.50.92.21.1-1.5-0.8-0.9-0.9-0.4-1.1-0.4-0.4-0.8-0.8-1.2-0.4-1.3-0.9-1.01.20.10.91.4-0.2-1.3
Run reversals in cocaine runway, females0.40.41.81.0-0.9-0.4-0.4-0.40.0-0.3-0.0-0.1-0.6-0.7-0.40.2-0.7-0.5-0.90.20.51.31.10.20.3
Run reversals in cocaine runway, males0.80.84.8-2.21.0-0.2-0.2-0.2-1.00.3-1.0-0.8-0.40.0-0.0-0.40.3-0.4-0.20.0-1.5-1.7-1.0-1.3-0.2
Latency to leave start box in cocaine runway0.30.31.50.10.30.80.80.90.40.40.30.40.80.30.1-0.70.30.40.5-0.20.50.3-1.20.4-0.2
Latency to leave start box in cocaine runway, F0.60.71.90.20.61.31.31.40.80.70.80.81.20.80.6-0.10.60.90.8-0.71.00.7-1.21.0-0.1
Latency to leave start box in cocaine runway, M0.60.61.7-0.4-0.6-0.6-0.6-0.7-0.8-0.6-0.9-0.9-0.6-0.9-1.0-1.3-0.8-0.9-0.60.9-0.7-0.6-0.3-0.8-0.7
Std. dev. time between licks in bursts1.11.56.7-2.22.01.11.11.10.11.20.10.21.21.11.1-0.51.10.71.1-1.2-0.1-1.6-2.6-0.31.4
Total sessions with >9 infusions0.60.71.60.2-0.8-1.3-1.2-1.2-0.7-0.5-0.6-0.7-1.3-1.1-0.7-0.4-0.8-0.9-1.10.7-0.70.30.5-0.6-0.2
Short access day 1 total inactive lever presses1.41.94.2-2.0-0.1-1.1-1.1-1.0-1.5-0.6-1.7-1.7-1.1-1.1-1.1-1.5-1.4-1.3-1.11.1-2.0-1.8-1.5-1.9-0.4
Short access day 10 total inactive lever presses0.10.30.70.20.50.50.50.40.60.70.50.30.70.70.50.70.90.50.4-0.30.70.4-0.20.40.4
Short access day 1 total infusions0.00.10.20.4-0.1-0.2-0.1-0.10.10.20.10.1-0.5-0.40.1-0.00.1-0.1-0.3-0.0-0.40.40.1-0.20.4
Short access day 10 total infusions0.50.61.50.5-0.8-1.2-1.2-1.1-0.4-0.5-0.5-0.6-1.1-1.0-0.60.0-1.1-0.7-1.00.5-0.40.40.8-0.3-0.0
Short access total infusions0.70.82.10.4-1.0-1.3-1.3-1.2-0.7-0.5-0.7-0.7-1.5-1.4-0.8-0.4-1.0-0.9-1.10.8-0.90.50.5-0.80.2
Short access day 1 locomotion1.01.32.31.10.80.90.90.81.51.41.41.30.90.91.31.41.01.20.9-1.31.01.0-0.01.11.5
Short access day 10 total locomotion0.20.42.6-1.40.40.1-0.00.1-0.6-0.2-0.6-0.60.0-0.3-0.2-0.8-0.5-0.3-0.20.1-0.7-1.1-1.6-0.6-0.2
Short access total locomotion0.10.10.9-0.30.3-0.1-0.2-0.1-0.00.30.0-0.0-0.0-0.20.1-0.0-0.2-0.0-0.1-0.1-0.10.1-0.90.00.9
One hour access (0.3 mA shock)1.11.32.71.10.70.60.70.81.41.31.41.50.80.81.11.41.01.21.0-1.11.51.20.41.41.6
Compulsive drug intake3.74.56.90.42.22.22.22.22.22.42.32.42.22.42.21.62.42.32.3-2.12.21.4-1.41.82.6
One hour access (shock baseline)0.40.72.30.3-0.9-1.2-1.2-1.1-0.6-0.7-0.7-0.6-1.0-1.0-0.70.0-0.9-0.7-0.80.6-0.7-0.41.5-0.4-0.7
Social response proportion0.20.21.4-0.90.5-0.1-0.1-0.1-0.20.2-0.20.00.10.10.3-0.70.2-0.10.2-0.3-0.5-1.0-1.2-0.70.3
Social responses0.30.41.4-0.7-0.2-0.6-0.6-0.5-0.6-0.5-0.6-0.4-0.3-0.4-0.4-1.2-0.5-0.6-0.40.2-0.6-0.7-1.0-0.8-0.1
Social time1.01.45.3-2.32.01.11.11.1-0.11.2-0.00.21.01.11.0-0.41.10.81.1-1.0-0.2-1.3-2.3-0.21.0
Soleus weight0.82.519.0-3.42.40.70.80.7-0.51.2-0.5-0.41.00.70.9-1.40.90.60.9-0.9-0.3-2.1-4.4-0.41.7
Bone: stiffness0.91.42.3-0.0-1.4-1.3-1.3-1.3-1.2-1.5-1.2-1.3-1.2-1.3-1.4-0.8-1.4-1.4-1.31.3-0.8-0.20.8-1.1-1.5
Tibialis anterior weight0.31.12.91.3-1.6-1.0-1.1-1.1-0.5-1.1-0.4-0.6-0.9-1.1-1.1-0.1-1.1-0.8-1.01.00.51.71.40.5-0.9
Time to tail flick, vehicle, before self-admin1.21.22.80.31.11.41.31.30.80.81.11.11.41.21.01.41.01.41.4-0.91.10.30.11.70.3
Time to tail flick, vehicle, after self-admin0.91.12.0-0.41.41.31.41.30.91.30.91.01.11.11.10.71.01.21.1-1.20.80.1-0.61.11.3
Time to tail flick, test, before self-admin0.20.20.70.30.10.40.30.30.20.20.20.20.20.20.30.60.30.30.2-0.30.50.80.70.80.0
Time to tail flick, test, after self-admin0.70.82.2-0.11.01.00.81.20.70.90.60.60.81.01.01.51.10.80.9-1.00.4-0.21.20.60.2
Delta time to tail flick, vehicle, before/after SA0.10.10.40.5-0.1-0.2-0.1-0.10.30.40.20.2-0.2-0.10.10.00.2-0.0-0.2-0.10.10.60.6-0.00.5
Delta time to tail flick, test, before/after SA0.20.20.60.70.10.20.30.40.70.30.60.50.40.50.30.80.10.40.4-0.30.3-0.10.70.2-0.2
Tibia length1.43.713.2-3.60.3-1.2-1.2-1.2-2.5-1.2-2.5-2.3-1.2-1.2-1.2-2.6-1.2-1.6-1.11.1-2.5-3.0-2.4-2.5-1.1
Ambulatory time before self-admin0.10.10.5-0.70.30.20.2-0.0-0.50.1-0.4-0.3-0.2-0.30.00.30.3-0.2-0.40.1-0.7-0.6-0.1-0.6-0.1
Ambulatory time after self-admin0.91.12.3-1.5-0.2-0.9-0.9-1.2-1.3-0.8-1.3-1.4-1.0-1.0-0.7-1.4-0.2-1.0-1.20.8-1.4-1.3-0.3-1.10.1
Bone: tissue strength3.73.85.7-1.0-1.8-2.2-2.1-2.2-2.4-2.2-2.3-2.3-2.0-2.2-2.1-2.0-2.1-2.1-2.12.1-1.7-0.7-0.1-1.6-1.7
Total heroin consumption0.10.10.5-0.50.50.20.3-0.1-0.10.2-0.0-0.10.20.20.2-0.10.20.10.0-0.2-0.2-0.7-0.3-0.20.6
Bone: trabecular number0.91.54.62.1-0.10.60.60.61.40.61.41.30.70.70.71.90.70.90.6-0.71.71.92.21.70.5
Bone: trabecular spacing2.63.46.0-2.4-0.6-1.6-1.6-1.6-2.4-1.5-2.3-2.2-1.5-1.6-1.6-2.5-1.6-1.8-1.61.6-2.3-1.9-2.1-2.2-1.1
Bone: trabecular thickness0.81.03.01.50.10.80.80.81.30.61.21.20.50.80.71.70.70.80.7-0.71.11.11.50.90.3
Bone: trabecular tissue density1.62.34.2-1.0-1.1-1.4-1.4-1.4-1.6-1.6-1.6-1.6-1.7-1.5-1.5-2.0-1.4-1.7-1.61.5-2.0-1.2-0.3-2.0-1.6
Water consumed over 24 hours0.10.10.7-0.40.20.10.10.1-0.20.1-0.0-0.00.30.0-0.0-0.60.00.20.1-0.10.3-0.0-0.80.30.1
Number of responses in last shaping day0.70.83.9-0.9-0.2-0.9-0.9-1.0-0.6-0.2-0.7-0.8-0.9-0.8-0.5-1.7-0.5-0.7-0.40.4-1.2-0.5-2.0-1.30.2