Hub : Genes

Pth1r

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio NM_020073.2 0.11 0.08 8.3e-12 0.09 0.1 0.1 0.11 6.7e-10 3.0e-11 1.2e-11 7.7e-12
2 Adipose mRNA stability Pth1r 0.31 0.18 1.1e-07 0.06 0.05 0.05 0.05 1.0e-06 3.1e-06 5.7e-06 5.4e-06
3 Adipose gene expression Pth1r 0.59 0.17 0.0e+00 0.4 0.4 0.4 0.39 8.2e-48 2.0e-47 1.9e-47 1.6e-46
4 Brain intron excision ratio chr8_110706784_110717073 0.09 0.07 7.7e-09 0.1 0.09 0.09 0.09 2.1e-09 8.5e-09 9.3e-09 7.4e-09
5 PL gene expression Pth1r 0.31 0.15 0.0e+00 0.28 0.31 0.31 0.31 2.2e-31 4.7e-35 3.2e-34 4.4e-34
6 Liver mRNA stability Pth1r 0.22 0.14 3.6e-11 0.09 0.09 0.09 0.09 3.1e-10 2.6e-10 3.8e-10 4.0e-10
7 Liver alternative polyA XM_008766651.2 0.07 0.05 1.5e-07 0.05 0.06 0.06 0.05 2.5e-06 5.3e-07 6.1e-07 1.8e-06
8 Liver alternative polyA NM_020073.2 0.06 0.04 4.8e-07 0.05 0.06 0.05 0.05 4.1e-06 1.0e-06 1.1e-06 2.3e-06
9 pVTA gene expression Pth1r 0.16 0.16 2.2e-04 0.07 0.07 0.08 0.06 6.0e-04 7.4e-04 1.7e-04 9.0e-04
10 NAcc gene expression Pth1r 0.17 0.1 0.0e+00 0.18 0.2 0.19 0.18 4.1e-20 2.5e-22 3.1e-21 5.4e-21
11 Brain alternative TSS XM_039082024.1 0.09 0.07 7.9e-10 0.09 0.1 0.09 0.09 9.0e-09 1.8e-09 6.6e-09 7.8e-09
12 NAcc alternative polyA XM_008766651.2 0.02 0.03 6.7e-03 0.01 0.01 0.01 0.01 1.5e-02 1.0e-02 4.3e-02 3.5e-02
13 Brain intron excision ratio chr8_110717192_110718303 0.09 0.06 2.6e-09 0.08 0.09 0.08 0.08 9.8e-08 7.0e-09 4.6e-08 3.7e-08
14 BLA gene expression Pth1r 0.62 0.22 0.0e+00 0.43 0.47 0.47 0.47 3.4e-25 4.8e-28 6.5e-28 5.9e-28
15 OFC gene expression Pth1r 0.28 0.18 7.2e-05 0.07 0.11 0.1 0.1 9.2e-03 1.5e-03 1.9e-03 2.7e-03
16 Liver alternative TSS XM_008766651.2 0.11 0.07 4.8e-14 0.13 0.13 0.13 0.13 2.0e-14 4.3e-14 3.1e-14 2.8e-14
17 Liver alternative TSS XM_039082029.1 0.11 0.07 1.2e-13 0.13 0.12 0.13 0.13 4.4e-14 9.3e-14 7.1e-14 6.2e-14
18 Adipose alternative polyA NM_020073.2 0.13 0.08 0.0e+00 0.16 0.15 0.15 0.15 5.3e-17 3.3e-16 1.9e-16 1.2e-16
19 Adipose alternative polyA XM_008766651.2 0.14 0.09 0.0e+00 0.17 0.16 0.16 0.16 3.7e-18 2.8e-17 1.9e-17 1.3e-17
20 Adipose isoform ratio NM_020073.2 0.13 0.08 0.0e+00 0.16 0.16 0.16 0.16 8.3e-18 2.8e-17 5.1e-17 1.5e-17
21 Brain alternative TSS XM_039082031.1 0.05 0.05 2.5e-04 0.04 0.03 0.02 0.03 2.7e-04 9.8e-04 2.8e-03 5.7e-04
22 Liver gene expression Pth1r 0.07 0.06 1.9e-08 0.07 0.05 0.06 0.06 6.8e-08 1.9e-06 6.3e-07 8.9e-07
23 Brain gene expression Pth1r 0.49 0.17 0.0e+00 0.24 0.25 0.24 0.24 5.1e-22 2.3e-23 1.5e-22 1.1e-22

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.00.00.30.1-0.2-0.20.20.20.2-0.20.2-0.50.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.20.10.2
Area under the delay curve2.22.32.6-1.51.51.5-1.5-1.5-1.61.6-1.61.2-1.5-1.51.5-1.6-1.6-1.61.6-1.61.5-1.51.5-1.4-1.3-1.6
BMI with tail0.41.22.41.2-1.4-1.41.41.21.6-1.21.2-0.51.11.1-1.21.11.01.0-1.11.1-0.80.8-0.80.71.01.1
BMI without tail1.83.74.71.8-2.0-2.02.12.02.2-2.02.0-1.91.91.9-2.01.91.91.9-2.02.0-1.81.8-1.81.81.41.7
Body weight6.728.332.15.4-5.6-5.65.55.55.7-5.55.4-4.95.45.4-5.45.45.45.3-5.35.3-5.25.2-5.25.04.65.1
Weight adjusted by age0.20.30.50.3-0.5-0.50.50.50.6-0.50.5-0.70.50.5-0.50.50.50.5-0.50.5-0.50.5-0.50.5-0.10.6
Bone surface0.00.10.3-0.40.10.1-0.1-0.2-0.20.2-0.20.0-0.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.30.3-0.3-0.6-0.3
Bone volume0.00.00.1-0.2-0.0-0.00.0-0.00.00.1-0.1-0.2-0.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.4-0.1
Breakpoint value in progressive ratio session0.10.10.50.7-0.3-0.30.10.30.2-0.30.3-0.20.30.3-0.20.30.30.3-0.40.4-0.30.3-0.30.30.70.2
Number of licking bursts0.10.20.6-0.30.40.4-0.4-0.5-0.50.4-0.40.8-0.4-0.40.4-0.4-0.4-0.40.3-0.30.4-0.40.4-0.4-0.2-0.2
Context. condit. distance diff. score0.00.00.0-0.0-0.0-0.00.10.00.0-0.00.0-0.00.00.0-0.00.00.00.0-0.00.0-0.00.0-0.00.0-0.20.0
Locomotion velocity, session 10.10.10.1-0.30.10.1-0.1-0.3-0.20.2-0.20.3-0.3-0.30.2-0.3-0.3-0.30.2-0.20.3-0.30.3-0.3-0.3-0.1
Locomotion distance, session 10.91.11.71.1-1.3-1.31.31.11.3-1.11.1-1.01.01.0-1.11.01.01.0-1.11.1-0.80.8-0.80.80.91.0
Locomotion velocity, session 20.30.30.4-0.50.40.4-0.4-0.5-0.40.5-0.50.6-0.6-0.60.6-0.6-0.6-0.60.5-0.50.7-0.70.7-0.7-0.7-0.5
Locomotion distance, session 20.00.00.1-0.1-0.2-0.20.2-0.10.20.0-0.1-0.0-0.1-0.10.1-0.1-0.1-0.1-0.00.00.3-0.30.3-0.3-0.40.1
Locomotion velocity, session 30.10.10.60.2-0.4-0.40.50.40.5-0.30.3-0.80.30.3-0.30.30.30.20.1-0.1-0.20.2-0.20.2-0.10.1
Locomotion distance, session 31.01.11.6-1.10.80.8-0.8-1.0-0.81.0-1.00.6-1.0-1.11.0-1.1-1.1-1.11.3-1.31.2-1.21.2-1.2-1.3-1.0
Stereotopy head waving bouts, day 30.00.00.10.2-0.1-0.10.10.20.2-0.20.20.30.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.20.20.3
Stereotopy head waving duration, day 30.30.30.50.6-0.5-0.50.50.50.5-0.50.6-0.40.60.6-0.60.60.60.6-0.70.7-0.60.6-0.60.60.50.7
Locomotion velocity, session 70.30.41.20.4-0.6-0.60.70.50.5-0.60.6-1.10.60.6-0.60.60.60.6-0.50.5-0.60.6-0.60.60.10.6
Locomotion distance, session 70.50.71.5-1.00.70.7-0.7-0.8-0.80.8-0.80.3-0.8-0.80.8-0.8-0.8-0.80.8-0.80.9-0.90.9-0.9-1.2-0.7
Stereotopy head waving bouts, day 70.10.10.3-0.30.40.4-0.3-0.2-0.30.3-0.30.2-0.2-0.30.3-0.3-0.3-0.30.3-0.30.2-0.20.2-0.2-0.2-0.5
Stereotopy head waving duration, day 70.20.20.30.5-0.4-0.40.50.50.5-0.50.5-0.50.50.5-0.50.50.50.5-0.40.4-0.50.5-0.50.50.60.2
Locomotion velocity, session 80.20.30.70.5-0.8-0.80.80.60.8-0.60.5-0.60.50.5-0.50.50.50.4-0.40.4-0.30.3-0.30.30.30.5
Locomotion distance, session 80.20.30.80.4-0.9-0.90.90.60.8-0.60.6-0.90.50.5-0.60.50.50.5-0.50.5-0.30.3-0.30.30.00.5
Degree of sensitization distance1.41.41.91.2-1.1-1.11.11.11.0-1.11.1-1.11.21.2-1.21.21.21.2-1.41.4-1.21.2-1.21.21.21.2
Degree of sensitization stereotypy0.00.00.20.10.10.1-0.00.1-0.1-0.00.0-0.30.10.1-0.00.00.00.00.1-0.1-0.20.2-0.20.20.2-0.4
Conditioned locomotion3.13.64.3-2.02.02.0-2.1-1.9-2.01.9-1.91.6-1.9-1.91.9-1.9-1.9-1.91.9-1.91.8-1.81.8-1.8-1.9-1.9
Cocaine response after cond. corrected0.20.20.30.6-0.4-0.40.50.50.5-0.50.50.00.50.5-0.50.50.50.5-0.40.4-0.60.6-0.60.50.60.5
Cocaine response after cond. not corrected1.71.92.11.5-1.3-1.31.51.41.4-1.41.4-0.91.41.4-1.41.41.41.4-1.31.3-1.41.4-1.41.31.41.4
Cocaine response before conditioning1.11.42.11.1-1.3-1.31.31.21.4-1.21.2-1.41.21.2-1.21.21.21.2-1.11.1-1.01.0-1.01.00.91.1
Saline control response1.41.92.71.3-1.2-1.21.21.31.3-1.41.4-1.61.41.4-1.41.41.41.4-1.41.4-1.41.4-1.41.41.31.4
Bone: connectivity density0.20.30.4-0.60.70.7-0.6-0.6-0.60.6-0.60.1-0.5-0.50.6-0.5-0.5-0.50.6-0.60.5-0.50.5-0.4-0.5-0.6
Bone: cortical apparent density0.30.40.5-0.70.70.7-0.7-0.6-0.70.6-0.60.4-0.6-0.60.6-0.6-0.6-0.60.7-0.70.5-0.50.5-0.6-0.6-0.7
Bone: cortical area0.10.20.7-0.50.30.3-0.3-0.4-0.40.4-0.40.7-0.4-0.40.4-0.4-0.4-0.40.3-0.30.4-0.40.4-0.4-0.9-0.3
Bone: cortical porosity0.00.00.1-0.20.30.3-0.3-0.2-0.30.2-0.2-0.2-0.2-0.10.2-0.1-0.1-0.10.1-0.10.0-0.00.00.00.1-0.1
Bone: cortical porosity0.10.10.3-0.40.50.5-0.6-0.5-0.50.4-0.4-0.0-0.4-0.40.4-0.4-0.4-0.40.3-0.30.3-0.30.3-0.2-0.2-0.3
Bone: cortical thickness0.10.10.20.3-0.4-0.40.40.40.4-0.40.40.10.40.4-0.40.40.40.4-0.40.4-0.40.4-0.40.4-0.00.4
Bone: cortical thickness0.00.00.00.1-0.1-0.10.10.10.1-0.10.1-0.00.10.1-0.10.10.10.1-0.10.1-0.10.1-0.10.10.00.1
Bone: cortical tissue density0.30.40.6-0.70.70.7-0.7-0.6-0.70.6-0.60.4-0.6-0.60.6-0.6-0.6-0.60.7-0.70.5-0.50.5-0.6-0.6-0.7
Condit. Reinf. active minus inactive responses0.10.10.20.3-0.2-0.20.20.30.2-0.30.3-0.30.30.3-0.30.40.40.4-0.40.4-0.40.4-0.40.40.20.4
Condit. Reinf. active-inactive response ratio0.20.30.40.5-0.4-0.40.40.50.4-0.50.5-0.40.50.5-0.50.50.50.5-0.60.6-0.60.6-0.60.60.50.6
Condit. Reinf. active responses0.00.00.1-0.20.30.3-0.3-0.1-0.30.2-0.20.1-0.1-0.10.2-0.1-0.1-0.10.2-0.20.0-0.00.0-0.0-0.3-0.3
Condit. Reinf. inactive responses0.70.91.3-1.01.01.0-1.0-0.8-0.90.9-0.90.8-0.9-0.90.9-0.9-0.9-0.91.2-1.20.8-0.80.8-0.8-1.0-1.1
Incentive salience index mean0.10.10.1-0.30.30.3-0.3-0.3-0.20.2-0.20.3-0.2-0.20.2-0.2-0.2-0.20.2-0.20.3-0.30.3-0.3-0.4-0.2
Condit. Reinf. lever presses1.62.12.4-1.51.31.3-1.3-1.4-1.31.4-1.41.5-1.5-1.51.4-1.5-1.5-1.51.4-1.41.6-1.61.6-1.6-1.5-1.2
Condit. Reinf. active minus inactive responses2.22.73.31.8-1.8-1.81.81.71.8-1.71.7-1.41.61.6-1.71.61.61.6-1.71.7-1.51.5-1.51.41.71.7
Condit. Reinf. active-inactive response ratio1.71.82.21.5-1.5-1.51.41.41.4-1.41.4-1.01.41.3-1.41.31.31.3-1.31.3-1.31.3-1.31.21.41.2
Condit. Reinf. active responses1.82.52.81.7-1.7-1.71.61.61.7-1.61.6-1.31.61.6-1.61.61.61.6-1.61.6-1.51.5-1.51.41.61.6
Condit. Reinf. inactive responses0.00.00.1-0.20.10.1-0.2-0.2-0.10.1-0.10.1-0.1-0.10.1-0.1-0.1-0.10.0-0.00.2-0.20.2-0.2-0.20.0
Condit. Reinf. lever presses2.53.44.32.0-2.1-2.12.01.92.0-1.91.9-1.61.81.8-1.91.81.81.8-1.81.8-1.71.7-1.71.71.81.8
Condit. Reinf. lever reinforcers received2.02.93.31.8-1.8-1.81.71.71.8-1.71.7-1.41.71.7-1.71.71.71.7-1.71.7-1.61.6-1.61.51.61.8
Conditioned reinforcement - actives0.30.30.8-0.60.70.7-0.7-0.7-0.40.5-0.50.9-0.6-0.50.4-0.5-0.5-0.50.4-0.40.7-0.70.7-0.7-0.20.1
Conditioned reinforcement - inactives0.91.01.4-1.11.01.0-1.0-1.0-1.01.0-1.01.2-1.0-1.01.0-1.0-1.0-1.01.0-1.01.1-1.11.1-1.0-1.2-0.8
Conditioned locomotion0.40.40.7-0.60.80.8-0.8-0.7-0.50.6-0.60.8-0.7-0.70.6-0.6-0.7-0.70.5-0.50.8-0.80.8-0.8-0.1-0.3
Patch foraging indifference point 0 sec1.11.72.81.2-1.4-1.41.31.31.3-1.31.3-1.71.31.3-1.31.31.31.3-1.31.3-1.21.2-1.21.20.91.4
Patch foraging indifference point AUC0.10.10.40.4-0.2-0.20.20.30.3-0.30.3-0.20.30.3-0.30.30.30.3-0.20.2-0.30.3-0.30.20.70.0
Delay disc. indifference point, 0s delay0.00.00.1-0.10.20.2-0.2-0.2-0.10.2-0.20.3-0.2-0.20.2-0.2-0.2-0.20.2-0.20.3-0.30.3-0.20.3-0.1
Delay disc. indifference point, 16s delay1.01.11.6-1.21.01.0-1.0-1.0-1.01.1-1.10.5-1.0-1.11.1-1.1-1.1-1.11.0-1.01.0-1.01.0-0.9-1.3-1.1
Delay disc. indifference point, 2s delay0.30.30.4-0.70.70.7-0.7-0.6-0.60.6-0.60.4-0.6-0.60.6-0.6-0.6-0.60.6-0.60.5-0.50.5-0.5-0.6-0.6
Delay disc. indifference point, 24s delay0.90.81.4-1.10.90.9-0.9-0.9-1.00.9-0.90.5-0.9-0.90.9-0.9-0.9-0.91.0-1.00.8-0.80.8-0.8-1.2-1.0
Delay disc. indifference point, 4s delay2.32.42.6-1.51.61.6-1.6-1.5-1.61.6-1.61.3-1.5-1.61.6-1.6-1.6-1.61.6-1.61.5-1.51.5-1.4-1.3-1.6
Delay disc. indifference point, 8s delay2.12.22.5-1.51.51.5-1.5-1.5-1.51.5-1.51.1-1.5-1.51.5-1.5-1.5-1.51.6-1.61.4-1.41.4-1.3-1.3-1.5
Indifference point function ln k0.20.31.2-0.60.10.1-0.2-0.4-0.20.4-0.40.3-0.5-0.50.4-0.5-0.5-0.50.4-0.40.7-0.70.7-0.7-1.1-0.2
Indifference point function log k0.20.31.2-0.60.10.1-0.2-0.4-0.20.4-0.40.3-0.5-0.50.4-0.5-0.5-0.50.4-0.40.7-0.70.7-0.7-1.1-0.2
Patch foraging total patch changes 0 sec1.22.02.61.3-1.5-1.51.41.41.4-1.41.4-1.61.41.4-1.51.41.41.4-1.51.5-1.31.3-1.31.31.11.6
Patch foraging total patch changes 12 sec0.91.11.61.1-1.1-1.11.01.11.0-1.11.1-1.31.11.1-1.11.11.11.1-0.90.9-1.01.0-1.01.11.10.8
Patch foraging total patch changes 18 sec2.73.44.71.9-1.6-1.61.61.71.8-1.81.9-1.71.91.9-1.91.91.91.9-2.12.1-1.71.7-1.71.82.22.1
Patch foraging total patch changes 24 sec3.23.94.52.1-2.1-2.12.02.02.0-2.02.0-1.82.02.0-2.02.02.02.0-2.02.0-1.81.8-1.82.02.11.8
Patch foraging total patch changes 6 sec0.10.20.50.4-0.5-0.50.30.40.3-0.40.4-0.70.40.4-0.40.40.40.4-0.30.3-0.40.4-0.40.40.40.2
Patch foraging time to switch 0 sec0.10.20.3-0.50.50.5-0.5-0.5-0.60.5-0.50.5-0.5-0.50.5-0.5-0.5-0.50.5-0.50.4-0.40.4-0.2-0.5-0.5
Patch foraging water rate 0 sec0.20.20.60.5-0.5-0.50.50.40.6-0.50.5-0.30.50.5-0.50.50.50.5-0.70.7-0.30.3-0.30.20.50.8
Patch foraging water rate 12 sec0.30.51.00.8-0.9-0.90.90.70.8-0.70.7-0.40.70.7-0.70.70.70.7-1.01.0-0.60.6-0.60.40.70.7
Patch foraging water rate 18 sec0.00.00.20.2-0.4-0.40.50.20.3-0.20.1-0.00.10.1-0.10.10.10.1-0.40.4-0.00.0-0.00.0-0.10.1
Patch foraging water rate 24 sec0.70.91.41.1-0.9-0.90.91.00.9-1.01.0-0.71.01.0-1.01.01.01.0-1.01.0-1.11.1-1.10.81.20.8
Patch foraging water rate 6 sec0.30.50.90.7-1.0-1.00.90.70.8-0.70.7-0.80.70.7-0.70.70.70.6-0.70.7-0.50.5-0.50.60.50.7
Seeking ratio, delayed vs. immediate footshock2.52.84.8-1.41.81.8-1.7-1.8-1.81.8-1.82.2-1.8-1.81.7-1.8-1.7-1.71.7-1.71.4-1.41.4-1.7-0.7-1.5
Distance traveled before self-admin0.00.00.1-0.2-0.2-0.20.30.10.1-0.10.1-0.10.10.1-0.10.10.10.1-0.00.0-0.10.1-0.10.1-0.20.2
Distance traveled after self-admin0.20.20.8-0.70.20.2-0.1-0.4-0.50.4-0.40.4-0.5-0.50.5-0.5-0.4-0.40.5-0.50.4-0.40.4-0.5-0.9-0.4
Extensor digitorum longus weight0.20.61.1-0.80.70.7-0.8-0.8-0.80.8-0.81.1-0.8-0.80.8-0.8-0.8-0.80.8-0.80.9-0.90.9-0.9-0.7-0.6
Bone: elastic displacement0.00.10.10.3-0.2-0.20.20.20.2-0.20.20.00.20.2-0.20.20.20.2-0.30.3-0.20.2-0.20.20.30.3
Bone: elastic work0.50.71.00.8-1.0-1.01.00.81.0-0.90.8-0.60.80.8-0.80.80.80.8-0.80.8-0.70.7-0.70.70.50.9
Bone: endosteal estimation0.10.20.60.4-0.5-0.50.50.40.4-0.40.4-0.70.40.4-0.40.40.50.5-0.60.6-0.50.5-0.50.50.30.6
Bone: endosteal perimeter1.22.43.5-1.71.41.4-1.4-1.6-1.51.6-1.61.4-1.6-1.61.6-1.6-1.6-1.61.4-1.41.6-1.61.6-1.7-1.9-1.4
Epididymis fat weight0.30.71.61.0-0.6-0.60.50.80.8-0.80.8-0.30.80.8-0.80.80.80.8-0.70.7-1.01.0-1.00.91.30.6
Delta time in closed arm before/after self-admin0.10.10.3-0.20.40.4-0.4-0.4-0.40.4-0.40.6-0.4-0.40.4-0.4-0.4-0.40.3-0.30.4-0.40.4-0.3-0.1-0.3
Delta time in open arm before/after self-admin0.30.31.20.0-0.6-0.60.60.50.5-0.50.5-1.10.50.5-0.50.50.60.5-0.50.5-0.60.6-0.60.5-0.40.5
Diff in mean of infusions in LGA sessions0.00.00.30.00.20.2-0.3-0.1-0.10.1-0.10.6-0.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.00.2-0.1
Delay discount exponential model param2.62.73.01.7-1.7-1.71.71.71.7-1.71.7-1.31.61.7-1.71.71.71.7-1.71.7-1.61.6-1.61.51.41.7
Extinction: sum of active levers before priming0.00.00.10.3-0.1-0.1-0.00.10.1-0.10.1-0.10.10.1-0.10.10.20.1-0.20.2-0.20.2-0.20.10.30.3
Active lever presses in extinction session 60.40.41.50.2-0.6-0.60.40.50.5-0.60.6-1.20.50.6-0.60.60.60.6-0.70.7-0.60.6-0.60.50.10.6
Bone: final force0.81.31.61.1-1.2-1.21.31.21.2-1.21.2-0.91.21.1-1.11.11.21.1-1.21.2-1.11.1-1.11.10.81.1
Bone: final moment1.11.72.11.3-1.4-1.41.51.41.4-1.31.3-1.01.31.3-1.31.31.31.3-1.41.4-1.31.3-1.31.30.91.3
Food consumed during 24 hour testing period1.51.82.11.3-1.4-1.41.41.31.4-1.41.3-1.21.31.3-1.31.31.31.3-1.41.4-1.21.2-1.21.21.21.3
Glucose0.30.41.00.8-0.7-0.70.70.70.7-0.60.6-0.70.60.6-0.60.60.60.6-0.50.5-0.50.5-0.50.61.00.5
Heart weight2.43.44.42.0-2.1-2.12.12.01.9-1.91.9-1.31.91.9-1.81.91.91.9-1.81.8-1.81.8-1.81.71.61.6
Delay discount hyperbolic model param2.52.73.01.7-1.7-1.71.71.71.7-1.71.7-1.31.61.7-1.71.71.71.7-1.71.7-1.61.6-1.61.51.41.7
Intermittent access intake day 1-15 change0.70.62.1-1.00.80.8-0.8-0.8-0.70.7-0.71.0-0.7-0.70.7-0.7-0.7-0.70.8-0.80.7-0.70.7-0.8-1.4-0.4
Intermittent access intake escalation0.50.52.1-0.90.70.7-0.7-0.7-0.60.6-0.60.8-0.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.60.6-0.7-1.5-0.3
Intermittent access intake escalation 20.10.10.6-0.2-0.1-0.10.10.10.2-0.20.2-0.10.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.1-0.80.4
Intermitt. access day 1 inactive lever presses0.00.00.0-0.10.00.0-0.0-0.0-0.00.0-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.10.10.2-0.20.2-0.0-0.1-0.1
Intermitt. access day 15 inactive lever presses0.70.81.4-1.00.80.8-0.8-0.8-0.90.9-0.90.8-0.9-0.90.9-0.9-0.9-0.90.8-0.80.9-0.90.9-0.8-1.2-1.0
Intermitt. access escalation Index0.00.00.2-0.1-0.0-0.00.00.00.0-0.00.0-0.50.00.0-0.00.00.00.0-0.10.10.0-0.00.00.0-0.20.1
Intermittent access day 1 total infusions0.00.00.1-0.20.20.2-0.2-0.2-0.10.1-0.10.1-0.1-0.10.1-0.1-0.1-0.1-0.00.00.3-0.30.3-0.2-0.10.1
Intermittent access day 15 total infusions0.30.41.6-0.90.70.7-0.7-0.6-0.50.5-0.50.6-0.6-0.50.5-0.5-0.5-0.50.5-0.50.6-0.60.6-0.7-1.3-0.1
Intermittent access terminal intake (last 3 days)0.20.21.0-0.70.50.5-0.5-0.4-0.20.3-0.30.2-0.3-0.30.3-0.3-0.3-0.30.2-0.20.5-0.50.5-0.5-1.00.1
Intermittent access total infusions0.50.51.3-1.00.80.8-0.8-0.8-0.60.7-0.70.6-0.7-0.70.6-0.7-0.7-0.70.5-0.50.9-0.90.9-0.8-1.1-0.2
Intermittent access day 1 locomotion0.10.10.2-0.30.30.3-0.3-0.3-0.30.3-0.30.3-0.3-0.30.3-0.3-0.3-0.30.2-0.20.4-0.40.4-0.3-0.2-0.2
Intermittent access day 15 total locomotion0.50.61.0-0.90.80.8-0.8-0.8-0.70.7-0.70.4-0.8-0.70.7-0.7-0.7-0.70.7-0.70.8-0.80.8-0.8-1.0-0.5
Intermittent access total locomotion1.21.31.6-1.31.21.2-1.2-1.2-1.11.1-1.11.0-1.2-1.11.1-1.1-1.1-1.11.0-1.01.3-1.31.3-1.2-1.1-0.9
Intermittent access standard deviation0.20.20.50.2-0.4-0.40.40.40.5-0.50.5-0.20.50.5-0.50.50.50.5-0.50.5-0.40.4-0.40.4-0.20.7
Left kidney weight0.61.82.81.4-1.6-1.61.71.51.6-1.41.4-1.31.31.3-1.31.31.31.3-1.01.0-1.21.2-1.21.11.10.8
Right kidney weight0.10.40.90.5-0.8-0.80.70.70.8-0.70.6-1.00.60.6-0.60.60.60.6-0.20.2-0.60.6-0.60.40.20.2
Cocaine induced anxiety0.60.70.8-0.90.80.8-0.8-0.8-0.80.8-0.80.9-0.8-0.80.8-0.8-0.8-0.80.9-0.90.8-0.80.8-0.8-0.9-0.8
Post-drug Anxiety0.20.30.6-0.40.40.4-0.4-0.5-0.60.5-0.50.6-0.5-0.50.6-0.5-0.5-0.50.7-0.70.4-0.40.4-0.4-0.5-0.8
Baseline Anxiety0.10.10.3-0.40.30.3-0.3-0.3-0.40.4-0.40.1-0.4-0.40.4-0.4-0.4-0.40.4-0.40.3-0.30.3-0.3-0.5-0.4
Tail length7.021.324.14.6-4.5-4.54.54.74.6-4.74.7-4.94.74.7-4.74.74.74.7-4.64.6-4.74.7-4.74.74.04.2
Length with tail9.735.637.26.0-6.0-6.06.06.16.0-6.16.1-6.16.16.1-6.06.06.16.0-5.95.9-6.06.0-6.05.95.15.6
Length without tail6.514.115.13.9-3.9-3.93.83.83.9-3.83.8-3.43.83.8-3.83.83.83.8-3.73.7-3.83.8-3.83.63.53.7
Times rat made contact with spout0.40.40.50.7-0.6-0.60.40.70.6-0.70.7-0.50.70.7-0.70.70.70.7-0.70.7-0.70.7-0.70.70.70.6
Lifetime Intake0.30.40.7-0.80.70.7-0.7-0.7-0.50.6-0.60.5-0.6-0.60.5-0.6-0.6-0.60.4-0.40.8-0.80.8-0.7-0.8-0.2
Liver weight, left0.10.10.50.3-0.1-0.1-0.10.20.0-0.20.2-0.70.30.3-0.20.20.30.3-0.20.2-0.40.4-0.40.50.50.0
Liver weight, right1.22.02.91.5-1.4-1.41.21.51.4-1.41.4-1.71.51.4-1.41.41.41.4-1.21.2-1.51.5-1.51.61.51.0
Locomotor activity5.99.410.63.0-3.1-3.13.23.13.2-3.23.1-3.03.13.1-3.23.13.13.1-3.13.1-2.92.9-2.92.82.53.3
Locomotor testing distance5.89.611.03.1-3.2-3.23.23.13.2-3.23.2-3.23.13.1-3.23.13.23.1-3.13.1-2.92.9-2.92.92.63.3
Locomotor testing rearing0.30.51.30.6-0.6-0.60.70.60.6-0.70.7-0.70.60.6-0.70.70.70.7-0.80.8-0.50.5-0.50.60.51.1
Locomotion in novel chamber0.20.31.2-0.20.50.5-0.5-0.5-0.40.5-0.51.1-0.5-0.50.4-0.5-0.5-0.50.5-0.50.6-0.60.6-0.60.3-0.2
Locomotion in novel chamber post-restriction0.80.92.01.1-0.9-0.90.91.01.0-1.01.0-0.51.01.0-1.01.01.01.0-0.90.9-0.90.9-0.90.81.41.0
Fecal boli incidents, locomotor time 10.40.50.90.8-0.7-0.70.70.70.7-0.70.7-0.20.70.7-0.70.70.70.7-0.80.8-0.60.6-0.60.60.90.7
Change in fecal boli incidents, locomotor task0.10.10.60.4-0.1-0.10.10.10.1-0.10.10.10.10.1-0.10.10.20.20.1-0.1-0.20.2-0.20.20.80.2
Time >=10cm from walls, locomotor time 10.10.10.2-0.30.30.3-0.3-0.3-0.40.4-0.40.1-0.4-0.30.4-0.4-0.4-0.40.4-0.40.3-0.30.3-0.3-0.3-0.5
Bouts of movement, locomotor time 10.00.00.20.3-0.1-0.10.10.10.1-0.10.10.00.10.1-0.10.10.10.1-0.20.2-0.10.1-0.10.10.50.1
Total resting periods, locomotor time 10.00.00.40.3-0.1-0.10.10.10.1-0.10.10.10.10.1-0.10.10.10.1-0.20.2-0.10.1-0.10.10.60.2
Rest time, locomotor task time 10.60.61.4-0.40.80.8-0.8-0.8-0.80.8-0.81.2-0.8-0.80.8-0.8-0.8-0.80.7-0.70.9-0.90.9-0.90.3-0.6
Distance moved, locomotor task time 11.71.82.31.2-1.4-1.41.41.41.4-1.41.4-1.41.41.4-1.41.41.31.3-1.51.5-1.41.4-1.41.40.91.2
Vertical activity count, locomotor time 10.80.81.00.9-0.9-0.90.91.00.9-0.90.9-0.90.90.9-0.90.90.90.9-1.01.0-1.01.0-1.01.00.80.7
Time >=10cm from walls, locomotor time 21.61.72.11.3-1.3-1.31.31.31.3-1.31.3-1.31.31.3-1.31.31.31.3-1.41.4-1.31.3-1.31.31.31.2
Bouts of movement, locomotor time 20.00.00.1-0.0-0.1-0.10.10.10.2-0.10.1-0.10.10.1-0.10.10.10.1-0.10.1-0.00.0-0.00.0-0.20.3
Total resting periods, locomotor time 20.00.00.2-0.30.20.2-0.2-0.2-0.10.2-0.20.2-0.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.20.2-0.2-0.40.0
Rest time, locomotor task time 20.00.00.20.00.10.1-0.1-0.2-0.20.2-0.20.5-0.2-0.20.1-0.2-0.1-0.20.2-0.20.2-0.20.2-0.20.4-0.0
Distance moved, locomotor task time 20.91.11.70.9-1.1-1.11.11.11.0-1.01.0-1.21.11.0-1.01.01.01.0-1.31.3-1.11.1-1.11.10.40.7
Vertical activity count, locomotor time 20.10.10.30.1-0.2-0.20.20.30.3-0.20.2-0.50.30.2-0.20.20.20.2-0.60.6-0.30.3-0.30.3-0.10.1
Light reinforcement 10.71.21.51.2-1.2-1.21.21.21.1-1.11.1-1.11.11.1-1.11.11.11.1-1.01.0-1.11.1-1.11.11.00.7
Light reinforcement 20.10.20.6-0.40.10.1-0.0-0.2-0.30.3-0.3-0.1-0.3-0.40.4-0.4-0.4-0.40.7-0.70.2-0.20.2-0.4-0.6-0.8
Bone: marrow area0.10.30.60.4-0.5-0.50.50.40.4-0.50.5-0.80.50.5-0.50.50.50.5-0.60.6-0.50.5-0.50.50.30.6
Bone: maximum diameter0.40.81.3-1.00.80.8-0.8-0.9-0.80.9-0.91.2-0.9-0.90.9-0.9-0.9-0.90.7-0.71.0-1.01.0-1.0-1.1-0.7
Bone: maximum force0.71.21.41.0-1.2-1.21.21.11.1-1.11.1-1.01.11.1-1.11.11.11.1-1.21.2-1.11.1-1.11.10.71.1
Bone: maximum moment0.81.41.71.1-1.3-1.31.31.21.2-1.21.2-1.11.21.2-1.21.21.21.2-1.31.3-1.21.2-1.21.20.71.2
Mean time between licks in bursts1.11.51.9-1.21.11.1-1.0-1.3-1.11.2-1.21.3-1.3-1.31.2-1.3-1.3-1.31.3-1.31.3-1.31.3-1.4-1.1-0.9
Mean num. licks in bursts0.50.61.30.7-0.8-0.80.70.90.9-0.80.8-1.10.80.8-0.80.80.80.8-0.70.7-0.80.8-0.80.80.60.6
Cd content in liver2.42.73.41.7-1.5-1.51.41.51.5-1.61.6-1.21.61.7-1.61.71.71.7-1.81.8-1.71.7-1.71.71.81.8
Co content in liver0.00.10.6-0.1-0.2-0.20.10.10.1-0.10.1-0.40.10.1-0.10.10.10.1-0.20.20.0-0.00.00.1-0.80.3
Cu content in liver4.25.17.12.4-2.2-2.22.22.22.2-2.22.2-2.02.22.3-2.32.32.32.3-2.32.3-2.22.2-2.22.22.72.3
Fe content in liver1.72.03.61.6-1.2-1.21.11.31.2-1.31.4-1.01.41.5-1.41.51.51.5-1.61.6-1.51.5-1.51.51.91.6
K content in liver0.70.71.11.0-1.0-1.00.90.91.0-0.90.9-0.70.80.8-0.80.80.80.8-0.70.7-0.70.7-0.70.81.10.6
Mg content in liver0.00.00.10.1-0.3-0.30.20.10.2-0.10.0-0.0-0.0-0.0-0.0-0.0-0.0-0.00.1-0.10.2-0.20.2-0.10.0-0.0
Mn content in liver0.70.81.70.8-1.1-1.11.00.91.1-0.90.9-1.30.80.8-0.90.80.80.8-0.70.7-0.60.6-0.60.70.40.8
Na content in liver0.40.40.60.6-0.4-0.40.40.60.4-0.60.6-0.80.60.6-0.60.60.60.6-0.70.7-0.70.7-0.70.70.70.6
Rb content in liver1.11.42.01.2-0.9-0.90.81.00.8-1.11.1-1.11.21.2-1.21.21.31.3-1.41.4-1.31.3-1.31.41.21.4
Se content in liver0.00.00.20.2-0.0-0.00.10.20.2-0.10.10.00.20.1-0.10.10.10.10.1-0.1-0.10.1-0.10.20.4-0.2
Sr content in liver0.00.00.10.1-0.3-0.30.30.10.3-0.10.1-0.10.00.0-0.10.00.0-0.00.1-0.10.1-0.10.1-0.1-0.1-0.1
Zn content in liver4.65.16.72.5-2.4-2.42.42.22.4-2.32.3-1.92.22.2-2.32.22.22.2-2.32.3-2.02.0-2.02.12.62.3
Bone: minimum diameter0.30.61.5-0.90.60.6-0.6-0.8-0.70.8-0.80.7-0.8-0.80.8-0.8-0.8-0.80.7-0.70.8-0.80.8-0.8-1.2-0.6
Time in familiar zone, hab. session 11.31.21.6-1.21.21.2-1.3-1.2-1.21.2-1.11.2-1.1-1.11.1-1.1-1.1-1.10.9-0.91.0-1.01.0-1.0-1.2-0.7
Time in novel zone, hab. session 10.50.50.70.7-0.7-0.70.80.80.8-0.80.7-0.80.80.7-0.70.70.70.7-0.60.6-0.80.8-0.80.80.60.4
Total zone transitions, hab. session 10.60.81.50.8-1.1-1.11.11.01.1-1.00.9-1.20.90.9-0.90.90.90.8-0.80.8-0.70.7-0.70.70.50.8
Total locomotion distance, hab. session 10.20.30.50.6-0.6-0.60.60.60.7-0.60.6-0.60.60.5-0.60.50.50.5-0.50.5-0.50.5-0.50.50.60.4
Locomotion velocity, hab. session 10.20.30.50.6-0.6-0.60.60.60.7-0.60.6-0.70.60.6-0.60.60.60.6-0.50.5-0.50.5-0.50.50.60.4
Time in familiar zone, hab. session 20.50.50.9-0.70.70.7-0.7-0.8-0.70.7-0.71.0-0.7-0.70.7-0.7-0.7-0.70.5-0.50.8-0.80.8-0.8-0.7-0.3
Time in novel zone, hab. session 20.00.00.20.1-0.2-0.20.20.20.1-0.20.2-0.40.20.2-0.20.20.20.2-0.10.1-0.20.2-0.20.20.10.1
Total zone transitions, hab. session 20.10.10.30.2-0.6-0.60.60.30.5-0.30.3-0.30.20.2-0.30.20.20.2-0.10.1-0.00.0-0.00.0-0.10.2
Total locomotion distance, hab. session 20.20.30.50.6-0.7-0.70.70.60.7-0.60.6-0.50.50.5-0.60.50.50.5-0.50.5-0.40.4-0.40.40.70.4
Locomotion velocity, hab. session 20.10.20.30.5-0.5-0.50.50.50.6-0.50.5-0.40.40.4-0.40.40.40.4-0.30.3-0.30.3-0.30.30.60.3
Novel to familiar place preference ratio1.01.02.10.9-1.0-1.01.10.91.0-1.01.0-1.50.90.9-1.00.90.90.9-1.31.3-0.90.9-0.90.91.01.0
Novelty place preference1.01.02.30.9-1.0-1.01.10.91.0-0.90.9-1.50.90.9-0.90.90.90.9-1.31.3-0.90.9-0.90.91.01.0
Time in novel zone, NPP test1.31.32.51.1-1.1-1.11.21.11.1-1.11.1-1.61.11.1-1.11.11.11.1-1.41.4-1.01.0-1.01.01.11.1
Total zone transitions, NPP test2.23.14.71.8-2.1-2.12.11.92.2-1.91.8-2.01.71.7-1.81.71.71.7-1.61.6-1.51.5-1.51.51.41.6
Total locomotion distance, NPP test0.91.31.71.2-1.2-1.21.21.21.3-1.21.2-1.11.11.1-1.11.11.11.1-1.01.0-1.01.0-1.01.01.20.9
Locomotion velocity, NPP test1.01.41.91.3-1.3-1.31.31.31.4-1.21.2-1.21.21.2-1.21.21.11.1-1.11.1-1.01.0-1.01.01.21.0
Intraocular pressure1.11.52.31.3-1.0-1.01.01.21.0-1.21.2-1.11.21.3-1.21.31.31.3-1.31.3-1.31.3-1.31.31.51.3
Delta distance traveled before/after self-admin0.20.20.6-0.50.30.3-0.2-0.4-0.40.4-0.40.3-0.5-0.40.5-0.5-0.5-0.50.4-0.40.4-0.40.4-0.5-0.8-0.6
Delta ambulatory time before/after self-admin0.30.30.50.4-0.6-0.60.70.60.5-0.50.5-0.70.50.5-0.50.50.50.5-0.70.7-0.50.5-0.50.50.00.4
Parametrial fat weight1.02.02.51.5-1.5-1.51.51.61.4-1.51.5-1.61.51.5-1.41.41.41.4-1.31.3-1.41.4-1.41.41.41.0
Pavlov. Cond. lever latency5.56.98.32.6-2.5-2.52.52.62.4-2.62.6-2.92.72.7-2.62.72.72.7-2.62.6-2.82.8-2.82.82.42.5
Pavlov. Cond. magazine entry latency6.88.810.3-3.02.82.8-2.8-3.0-2.83.0-3.03.2-3.0-3.03.0-3.0-3.0-3.02.9-2.93.0-3.03.0-3.0-3.0-2.6
Pavlov. Cond. change in total contacts1.81.93.0-1.31.41.4-1.3-1.4-1.41.4-1.41.7-1.4-1.41.4-1.4-1.4-1.41.3-1.31.4-1.41.4-1.4-1.1-1.1
Pavlov. Cond. index score6.78.510.8-2.92.82.8-2.8-3.0-2.82.9-2.93.3-3.0-3.02.9-3.0-3.0-3.02.8-2.83.0-3.03.0-3.0-2.7-2.6
Pavlov. Cond. latency score6.68.410.1-2.92.82.8-2.8-2.9-2.72.9-2.93.2-2.9-2.92.9-2.9-2.9-2.92.8-2.83.0-3.03.0-3.0-2.7-2.6
Pavlov. Cond. lever contacts3.23.85.0-1.91.81.8-1.8-1.9-1.81.9-1.92.2-2.0-2.01.9-2.0-2.0-2.01.9-1.92.1-2.12.1-2.1-1.7-1.8
Pavlov. Cond. magazine entry number7.89.711.63.1-3.0-3.03.03.23.0-3.13.1-3.43.23.1-3.13.13.13.1-3.03.0-3.23.2-3.23.23.02.7
Pavlov. Cond. intertrial magazine entries0.40.50.80.6-0.7-0.70.70.70.7-0.70.7-0.90.70.7-0.70.70.80.7-0.60.6-0.80.8-0.80.80.50.7
Pavlov. Cond. lever-magazine prob. diff.6.07.510.1-2.72.62.6-2.6-2.8-2.62.7-2.73.2-2.8-2.82.7-2.8-2.8-2.82.6-2.62.9-2.92.9-2.9-2.5-2.4
Pavlov. Cond. response bias7.49.011.4-3.02.92.9-2.9-3.0-2.93.0-3.03.4-3.0-3.03.0-3.0-3.0-3.02.9-2.93.1-3.13.1-3.1-2.8-2.7
Pavlov. Cond. lever latency0.50.61.0-0.81.01.0-1.0-0.8-1.00.8-0.80.7-0.8-0.80.8-0.8-0.8-0.70.9-0.90.6-0.60.6-0.6-0.7-0.9
Pavlov. Cond. magazine entry latency0.10.10.3-0.30.10.1-0.0-0.3-0.10.3-0.30.5-0.4-0.40.3-0.4-0.4-0.40.3-0.30.5-0.50.5-0.5-0.4-0.2
Pavlov. Cond. change in total contacts2.63.64.72.0-2.2-2.22.11.92.1-1.91.9-1.61.91.9-1.91.91.91.9-2.02.0-1.71.7-1.71.71.82.1
Pavlov. Cond. index score0.10.10.40.4-0.6-0.60.60.40.5-0.40.3-0.10.30.3-0.30.30.30.3-0.40.4-0.10.1-0.10.10.30.4
Pavlov. Cond. latency score0.10.10.30.3-0.5-0.50.50.30.5-0.30.3-0.00.20.2-0.30.20.20.2-0.30.3-0.10.1-0.10.10.20.4
Pavlov. Cond. lever contacts1.11.52.01.3-1.4-1.41.41.21.4-1.21.2-1.11.21.2-1.21.21.21.2-1.31.3-1.01.0-1.01.01.21.2
Pavlov. Cond. magazine entry number0.30.40.70.6-0.4-0.40.40.60.4-0.60.6-0.80.70.7-0.60.60.60.7-0.50.5-0.80.8-0.80.80.70.3
Pavlov. Cond. intertrial magazine entries0.40.50.7-0.80.80.8-0.8-0.8-0.90.7-0.70.5-0.7-0.70.7-0.6-0.6-0.60.4-0.40.6-0.60.6-0.6-0.8-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.4-0.6-0.60.60.30.5-0.30.3-0.00.30.2-0.30.30.30.2-0.30.3-0.10.1-0.10.10.20.4
Pavlov. Cond. response bias0.10.10.40.4-0.6-0.60.50.30.5-0.30.3-0.10.30.3-0.30.30.30.2-0.40.4-0.10.1-0.10.10.30.5
Time in closed arm before self-admin1.61.92.61.2-1.4-1.41.31.31.5-1.41.4-1.21.41.4-1.51.41.41.4-1.31.3-1.41.4-1.41.21.01.6
Time in closed arm after self-admin0.00.00.10.3-0.1-0.10.10.10.2-0.10.10.40.10.1-0.20.10.10.1-0.10.1-0.10.1-0.10.10.20.3
Time in open arm before self-admin1.21.31.7-1.11.31.3-1.3-1.1-1.21.2-1.21.0-1.2-1.21.2-1.2-1.2-1.20.8-0.81.2-1.21.2-0.9-0.8-1.3
Time in open arm after self-admin0.20.31.5-0.90.50.5-0.4-0.4-0.40.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.40.3-0.30.4-0.40.4-0.4-1.2-0.4
Bone: periosteal estimation0.00.00.10.0-0.2-0.20.30.10.2-0.20.1-0.20.10.1-0.20.10.20.1-0.30.3-0.10.1-0.10.1-0.30.3
Bone: periosteal perimeter1.22.03.2-1.61.31.3-1.3-1.4-1.41.4-1.41.4-1.4-1.41.4-1.4-1.4-1.41.3-1.31.5-1.51.5-1.5-1.8-1.2
Bone: post-yield work0.00.00.10.2-0.3-0.30.30.20.2-0.20.2-0.30.20.2-0.20.20.20.2-0.30.3-0.20.2-0.20.1-0.00.2
Progressive ratio test 1 active lever presses0.00.00.1-0.10.20.2-0.2-0.10.00.0-0.0-0.1-0.1-0.0-0.0-0.0-0.0-0.0-0.10.10.2-0.20.2-0.2-0.00.3
Progressive ratio test 1 breakpoint0.00.00.1-0.20.20.2-0.2-0.2-0.10.1-0.10.1-0.2-0.20.1-0.1-0.1-0.10.1-0.10.3-0.30.3-0.2-0.10.1
Progressive ratio test 1 inactive lever presses0.40.40.9-0.60.70.7-0.7-0.7-0.60.6-0.61.0-0.6-0.60.6-0.6-0.6-0.60.5-0.50.7-0.70.7-0.7-0.4-0.4
Progressive ratio test 2 active lever presses1.01.01.3-1.11.11.1-1.1-1.0-0.91.0-1.00.9-1.0-1.01.0-1.0-1.0-1.00.9-0.91.1-1.11.1-1.1-1.1-0.7
Progressive ratio test 2 breakpoint0.80.91.1-1.11.01.0-1.0-1.0-0.80.9-0.90.9-0.9-0.90.9-0.9-0.9-0.90.8-0.81.0-1.01.0-1.0-1.0-0.6
Progressive ratio test 2 inactive lever presses2.22.53.5-1.81.61.6-1.6-1.6-1.41.5-1.51.7-1.6-1.61.5-1.5-1.5-1.51.4-1.41.7-1.71.7-1.6-1.9-1.1
Incentive Sensitization - Responses1.81.81.9-1.41.41.4-1.4-1.3-1.31.4-1.41.3-1.4-1.41.4-1.4-1.4-1.41.3-1.31.4-1.41.4-1.4-1.2-1.3
Incentive Sensitization - Breakpoint1.71.81.8-1.41.41.4-1.4-1.3-1.31.3-1.31.3-1.3-1.31.4-1.3-1.3-1.31.3-1.31.3-1.31.3-1.4-1.3-1.3
Sum of active levers in priming session hrs 5-60.50.51.00.6-0.7-0.70.50.70.6-0.70.7-1.00.70.7-0.70.70.70.7-0.80.8-0.70.7-0.70.70.70.5
Progressive ratio3.64.15.32.2-2.1-2.12.12.02.1-2.02.0-1.82.02.0-2.12.02.02.0-1.91.9-1.91.9-1.92.02.32.1
Food seeking constrained by brief footshock0.81.01.9-1.21.01.0-0.9-1.0-0.91.0-1.00.8-1.0-1.00.9-1.0-1.0-1.00.9-0.91.0-1.01.0-1.1-1.4-0.8
Seeking ratio, punishment vs. effort5.66.99.1-2.82.62.6-2.7-2.6-2.62.6-2.62.4-2.6-2.62.6-2.6-2.6-2.62.4-2.42.6-2.62.6-2.7-3.0-2.6
Retroperitoneal fat weight0.61.92.41.4-1.5-1.51.41.51.4-1.41.4-1.61.41.4-1.41.41.41.4-1.21.2-1.51.5-1.51.41.01.0
Reaction time number correct0.30.41.1-0.80.60.6-0.6-0.7-0.70.7-0.70.6-0.7-0.60.7-0.6-0.6-0.60.2-0.20.6-0.60.6-0.8-1.0-0.5
Reaction time mean minus median0.00.00.20.3-0.2-0.20.20.30.3-0.20.2-0.00.20.2-0.20.20.20.20.2-0.2-0.20.2-0.20.10.40.1
Reaction time mean minus median AUC0.20.31.00.7-0.5-0.50.50.50.5-0.50.5-0.30.50.5-0.50.50.50.5-0.20.2-0.50.5-0.50.41.00.4
Reaction time num false alarms0.30.41.4-0.80.70.7-0.6-0.6-0.70.6-0.60.4-0.6-0.60.6-0.6-0.6-0.60.5-0.50.5-0.50.5-0.6-1.2-0.4
Reaction time num false alarms AUC0.10.10.9-0.50.40.4-0.3-0.3-0.40.3-0.3-0.1-0.3-0.20.3-0.2-0.2-0.20.2-0.20.1-0.10.1-0.2-0.9-0.3
Reaction time trials correct on left0.30.41.1-0.80.60.6-0.6-0.7-0.70.7-0.70.6-0.7-0.60.7-0.6-0.6-0.60.2-0.20.6-0.60.6-0.8-1.0-0.5
Reaction time trials on left0.30.51.1-0.80.60.6-0.7-0.7-0.70.7-0.70.6-0.7-0.70.7-0.7-0.7-0.70.2-0.20.6-0.60.6-0.8-1.1-0.5
Reaction time mean0.00.00.10.10.10.1-0.10.10.1-0.10.1-0.10.10.1-0.10.10.10.1-0.00.0-0.20.2-0.20.10.30.3
Reaction time mean AUC0.00.00.00.00.20.2-0.2-0.00.0-0.00.0-0.10.00.0-0.00.00.00.00.1-0.1-0.10.1-0.10.00.20.1
Median of all reaction times0.00.00.10.00.10.1-0.10.10.1-0.10.1-0.20.10.1-0.10.10.10.1-0.20.2-0.20.2-0.20.20.10.2
Reaction time omissions0.30.40.9-0.60.90.9-1.0-0.6-0.80.6-0.60.6-0.6-0.60.6-0.6-0.6-0.50.4-0.40.4-0.40.4-0.4-0.2-0.6
Reaction time false alarm rate0.00.00.3-0.30.30.3-0.2-0.2-0.20.2-0.2-0.0-0.1-0.10.2-0.1-0.1-0.10.3-0.30.1-0.10.1-0.1-0.5-0.2
Reaction time premature initiation rate1.92.63.11.7-1.6-1.61.61.71.6-1.71.7-1.61.71.7-1.61.71.61.7-1.51.5-1.71.7-1.71.61.61.3
Reaction time premature initiations0.91.31.51.1-1.2-1.21.11.21.1-1.11.1-1.21.11.2-1.11.11.11.1-1.21.2-1.21.2-1.21.00.80.8
Std. dev. reaction times0.10.10.30.4-0.2-0.20.10.30.4-0.40.4-0.30.30.4-0.40.40.30.4-0.10.1-0.40.4-0.40.20.50.4
Reaction time trials completed0.30.51.1-0.80.60.6-0.7-0.7-0.70.7-0.70.6-0.7-0.70.7-0.7-0.7-0.70.2-0.20.6-0.60.6-0.8-1.1-0.5
Reaction time trials AUC0.40.61.3-0.90.80.8-0.7-0.8-0.80.8-0.80.7-0.8-0.80.8-0.8-0.8-0.80.2-0.20.7-0.70.7-0.9-1.1-0.5
Run reversals in cocaine runway, females2.02.02.7-1.61.51.5-1.5-1.3-1.41.4-1.41.0-1.3-1.31.4-1.4-1.4-1.41.6-1.61.2-1.21.2-1.2-1.6-1.5
Run reversals in cocaine runway, males0.50.50.80.8-0.8-0.80.90.80.7-0.70.7-0.60.70.7-0.70.70.70.7-0.80.8-0.80.8-0.80.80.60.5
Latency to leave start box in cocaine runway0.40.41.20.9-0.7-0.70.70.60.6-0.60.6-0.30.60.6-0.60.60.50.6-0.60.6-0.40.4-0.40.81.10.4
Latency to leave start box in cocaine runway, F1.31.41.91.3-1.4-1.41.41.21.3-1.21.2-0.81.21.2-1.21.21.21.2-1.31.3-1.01.0-1.01.11.01.1
Latency to leave start box in cocaine runway, M0.40.40.6-0.20.60.6-0.8-0.6-0.60.6-0.60.4-0.6-0.60.6-0.6-0.6-0.60.7-0.70.6-0.60.6-0.20.4-0.8
Std. dev. time between licks in bursts3.84.56.1-2.11.91.9-1.9-2.2-2.02.1-2.12.5-2.2-2.22.1-2.2-2.1-2.22.0-2.02.3-2.32.3-2.3-2.2-1.6
Total sessions with >9 infusions0.10.10.8-0.10.30.3-0.3-0.3-0.20.2-0.20.9-0.3-0.20.2-0.2-0.2-0.20.1-0.10.3-0.30.3-0.30.10.1
Short access day 1 total inactive lever presses3.53.95.3-1.92.02.0-2.0-2.1-1.92.0-2.02.3-2.0-2.01.9-2.0-2.0-2.01.8-1.82.1-2.12.1-2.0-1.7-1.4
Short access day 10 total inactive lever presses0.00.00.1-0.0-0.0-0.00.0-0.1-0.10.1-0.10.3-0.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.10.0-0.2-0.3
Short access day 1 total infusions0.90.91.6-0.81.01.0-1.0-1.0-1.01.0-1.01.3-1.0-1.01.0-1.0-1.0-1.00.9-0.91.0-1.01.0-1.0-0.4-0.8
Short access day 10 total infusions0.10.10.2-0.30.30.3-0.3-0.2-0.10.2-0.20.2-0.2-0.20.1-0.2-0.2-0.2-0.00.00.4-0.40.4-0.3-0.30.2
Short access total infusions0.50.50.7-0.80.80.8-0.8-0.8-0.70.7-0.70.7-0.7-0.70.7-0.7-0.7-0.70.6-0.60.8-0.80.8-0.8-0.6-0.4
Short access day 1 locomotion0.10.10.2-0.10.30.3-0.3-0.2-0.20.2-0.20.5-0.2-0.20.2-0.2-0.2-0.20.1-0.10.3-0.30.3-0.30.2-0.1
Short access day 10 total locomotion0.00.00.30.2-0.1-0.10.10.10.2-0.20.2-0.10.20.2-0.20.20.20.2-0.20.2-0.10.1-0.10.10.60.3
Short access total locomotion0.00.00.20.00.20.2-0.2-0.1-0.00.1-0.10.3-0.1-0.10.1-0.1-0.1-0.1-0.00.00.2-0.20.2-0.20.50.1
One hour access (0.3 mA shock)0.10.20.7-0.60.50.5-0.5-0.4-0.20.3-0.30.0-0.4-0.30.3-0.3-0.3-0.30.2-0.20.4-0.40.4-0.5-0.80.1
Compulsive drug intake0.00.00.2-0.0-0.0-0.00.0-0.1-0.10.1-0.1-0.4-0.1-0.10.1-0.1-0.1-0.10.1-0.1-0.00.0-0.00.0-0.0-0.2
One hour access (shock baseline)0.10.10.6-0.50.40.4-0.4-0.3-0.10.2-0.20.2-0.2-0.20.1-0.2-0.2-0.20.0-0.00.4-0.40.4-0.4-0.80.3
Social response proportion0.40.50.90.6-0.6-0.60.60.70.5-0.70.7-0.90.70.7-0.60.70.70.7-0.70.7-0.80.8-0.80.80.40.3
Social responses0.40.50.80.6-0.7-0.70.70.70.7-0.70.7-0.90.70.7-0.60.70.70.7-0.80.8-0.60.6-0.60.60.40.4
Social time0.50.71.9-1.00.80.8-0.6-0.7-0.90.8-0.80.4-0.8-0.80.9-0.8-0.8-0.80.9-0.90.7-0.70.7-0.6-1.4-1.2
Soleus weight4.011.613.23.6-3.6-3.63.63.53.6-3.53.4-3.23.43.4-3.43.43.43.4-3.43.4-3.23.2-3.23.33.23.3
Bone: stiffness0.10.20.30.4-0.4-0.40.40.40.4-0.40.4-0.50.50.5-0.40.50.50.5-0.50.5-0.50.5-0.50.50.20.4
Tibialis anterior weight0.00.00.10.2-0.2-0.20.20.20.2-0.20.20.10.10.1-0.20.20.10.1-0.10.1-0.20.2-0.20.10.10.2
Time to tail flick, vehicle, before self-admin2.02.13.71.8-1.4-1.41.41.41.4-1.41.4-1.11.41.4-1.41.41.41.4-1.31.3-1.41.4-1.41.61.91.3
Time to tail flick, vehicle, after self-admin0.60.60.90.6-0.9-0.90.80.80.8-0.80.8-0.90.80.8-0.70.70.70.7-0.80.8-0.70.7-0.70.60.80.6
Time to tail flick, test, before self-admin0.10.10.40.2-0.2-0.20.20.30.1-0.10.1-0.70.20.1-0.10.10.10.1-0.30.3-0.20.2-0.20.30.2-0.4
Time to tail flick, test, after self-admin0.20.20.3-0.40.60.6-0.5-0.4-0.40.4-0.40.5-0.4-0.40.4-0.4-0.4-0.40.1-0.10.5-0.50.5-0.2-0.1-0.3
Delta time to tail flick, vehicle, before/after SA0.50.50.9-0.90.60.6-0.6-0.7-0.70.7-0.70.6-0.7-0.70.7-0.7-0.7-0.70.6-0.60.7-0.70.7-0.9-0.8-0.7
Delta time to tail flick, test, before/after SA0.30.30.9-0.40.60.6-0.6-0.6-0.40.5-0.51.0-0.5-0.50.4-0.5-0.5-0.50.5-0.50.6-0.60.6-0.6-0.3-0.1
Tibia length6.819.122.94.5-4.8-4.84.84.64.7-4.54.5-4.34.44.4-4.44.44.44.4-4.24.2-4.14.1-4.14.13.84.1
Ambulatory time before self-admin0.00.00.3-0.30.10.1-0.1-0.3-0.20.2-0.20.3-0.2-0.20.2-0.2-0.2-0.20.3-0.30.2-0.20.2-0.2-0.5-0.0
Ambulatory time after self-admin0.00.00.4-0.4-0.1-0.10.1-0.1-0.20.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.0-0.00.0-0.1-0.7-0.1
Bone: tissue strength3.23.13.41.8-1.8-1.81.81.81.8-1.81.8-1.51.81.8-1.81.81.81.8-1.81.8-1.71.7-1.71.71.41.8
Total heroin consumption1.31.52.31.2-1.3-1.31.11.21.2-1.21.2-1.21.21.2-1.21.21.21.2-1.51.5-1.21.2-1.21.10.81.1
Bone: trabecular number0.60.91.2-1.10.90.9-0.9-0.9-0.90.9-0.90.4-0.9-0.90.9-0.9-1.0-1.01.0-1.01.0-1.01.0-1.0-1.1-0.9
Bone: trabecular spacing1.31.72.01.4-1.3-1.31.31.41.2-1.31.3-1.01.41.3-1.31.31.41.3-1.41.4-1.41.4-1.41.41.31.1
Bone: trabecular thickness0.00.00.20.2-0.2-0.20.20.20.2-0.20.1-0.40.10.1-0.10.10.10.1-0.00.0-0.10.1-0.10.10.2-0.0
Bone: trabecular tissue density0.20.30.60.5-0.6-0.60.60.60.6-0.60.6-0.70.60.6-0.60.60.60.6-0.60.6-0.60.6-0.60.50.40.4
Water consumed over 24 hours0.00.00.2-0.1-0.0-0.0-0.2-0.1-0.00.1-0.10.4-0.1-0.10.1-0.1-0.1-0.10.0-0.00.2-0.20.2-0.2-0.2-0.1
Number of responses in last shaping day0.80.81.5-1.00.90.9-0.9-0.9-0.80.9-0.90.9-0.9-0.90.8-0.9-0.8-0.90.8-0.80.9-0.90.9-0.9-1.2-0.6