Hub : Genes

Flot1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Flot1 0.32 0.16 0.0e+00 0.16 0.2 0.19 0.18 2.9e-14 1.2e-18 8.8e-18 2.6e-16
2 LHb gene expression Flot1 0.17 0.11 5.3e-03 0.09 0.1 0.08 0.09 3.2e-03 2.8e-03 7.4e-03 3.8e-03
3 Liver gene expression Flot1 0.31 0.13 0.0e+00 0.21 0.24 0.24 0.24 1.1e-22 3.4e-26 1.5e-26 2.3e-26
4 IL gene expression Flot1 0.55 0.15 2.3e-10 0.27 0.31 0.32 0.31 4.0e-07 2.6e-08 1.9e-08 4.0e-08
5 BLA gene expression Flot1 0.49 0.19 6.6e-15 0.21 0.18 0.18 0.21 2.0e-11 5.6e-10 8.1e-10 2.3e-11
6 BLA intron excision ratio chr20_2927515_2927812 0.12 0.07 2.5e-04 0.05 0.05 0.05 0.05 8.6e-04 1.4e-03 1.0e-03 1.6e-03
7 Adipose gene expression Flot1 0.27 0.14 0.0e+00 0.23 0.23 0.23 0.23 1.3e-25 1.5e-25 9.3e-26 2.0e-25
8 Liver isoform ratio XM_006256024.4 0.03 0.02 1.7e-03 0.02 0.02 0.02 0.02 4.5e-03 5.0e-03 4.8e-03 3.4e-03
9 OFC gene expression Flot1 0.5 0.19 3.8e-07 0.19 0.18 0.17 0.19 2.3e-05 4.8e-05 6.8e-05 3.2e-05
10 NAcc gene expression Flot1 0.05 0.04 6.3e-04 0.04 0.02 0.03 0.03 5.2e-05 1.6e-03 1.5e-04 5.3e-04
11 PL gene expression Flot1 0.49 0.24 0.0e+00 0.25 0.27 0.3 0.27 7.3e-27 5.8e-30 4.0e-33 5.1e-30

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.02.70.50.00.20.90.91.61.10.91.4-1.6-0.0
Area under the delay curve2.02.15.11.21.3-1.3-1.7-1.6-1.0-2.3-1.6-1.50.6-1.1
BMI with tail1.65.37.21.72.2-2.3-2.6-2.6-2.6-2.2-2.7-2.2-0.6-2.7
BMI without tail2.24.58.90.91.7-2.0-2.5-2.5-3.0-2.2-2.6-1.80.3-2.3
Body weight3.615.132.51.02.7-3.7-4.6-4.5-5.7-3.5-4.6-4.20.4-4.4
Weight adjusted by age1.61.84.20.10.7-1.0-1.7-1.7-2.0-1.2-1.6-1.31.1-1.2
Bone surface0.10.10.4-0.4-0.20.1-0.1-0.1-0.5-0.1-0.10.60.6-0.4
Bone volume0.20.31.10.40.5-0.5-0.4-0.4-0.3-0.2-0.40.3-0.6-1.1
Breakpoint value in progressive ratio session0.80.91.3-0.4-0.91.11.11.01.20.81.01.10.50.8
Number of licking bursts1.21.42.8-1.3-1.31.21.01.00.40.21.01.51.61.7
Context. condit. distance diff. score8.610.313.1-3.1-3.53.63.53.52.63.33.53.11.73.6
Locomotion velocity, session 10.40.50.8-0.9-0.80.50.70.70.40.80.70.60.10.8
Locomotion distance, session 10.20.31.00.80.6-0.3-0.00.00.80.10.0-0.0-1.0-0.2
Locomotion velocity, session 20.10.20.3-0.5-0.50.60.30.3-0.00.30.30.10.60.4
Locomotion distance, session 20.20.20.70.0-0.10.40.40.50.80.70.50.5-0.50.2
Locomotion velocity, session 30.40.51.00.80.9-1.0-0.6-0.6-0.1-0.5-0.6-0.6-1.0-0.4
Locomotion distance, session 30.90.91.8-0.3-0.60.81.11.11.31.21.11.1-0.70.9
Stereotopy head waving bouts, day 30.50.62.2-0.7-0.2-0.3-0.7-0.7-1.5-0.8-0.7-0.31.1-0.0
Stereotopy head waving duration, day 30.40.41.6-0.40.0-0.5-0.7-0.7-1.3-0.9-0.7-0.20.8-0.1
Locomotion velocity, session 73.43.76.0-1.0-1.51.82.22.22.32.12.22.5-0.11.9
Locomotion distance, session 72.32.96.2-0.3-1.11.82.01.92.51.51.92.1-0.11.7
Stereotopy head waving bouts, day 71.41.63.00.40.9-1.4-1.4-1.4-1.6-1.2-1.4-1.7-0.2-1.3
Stereotopy head waving duration, day 71.61.93.90.30.9-1.5-1.6-1.6-2.0-1.2-1.6-1.8-0.1-1.5
Locomotion velocity, session 82.93.57.7-2.8-2.42.01.51.5-0.11.21.51.52.52.1
Locomotion distance, session 84.46.58.7-2.4-2.73.02.82.82.22.82.82.51.12.7
Degree of sensitization distance1.11.12.3-0.9-1.11.40.90.90.60.50.91.01.51.1
Degree of sensitization stereotypy1.11.22.50.50.9-1.1-1.2-1.1-1.3-0.9-1.2-1.6-0.2-1.3
Conditioned locomotion0.20.21.0-0.30.0-0.2-0.5-0.5-1.0-0.4-0.50.20.6-0.2
Cocaine response after cond. corrected0.30.30.70.0-0.30.70.50.60.8-0.00.60.50.60.6
Cocaine response after cond. not corrected0.40.42.6-0.7-0.60.60.10.2-0.3-0.30.20.01.60.5
Cocaine response before conditioning1.61.97.1-0.70.2-0.9-1.4-1.4-2.7-1.2-1.5-1.61.4-0.7
Saline control response2.43.25.01.72.0-2.2-1.8-1.7-1.2-1.2-1.7-1.9-2.0-1.9
Bone: connectivity density1.72.75.0-0.7-1.11.21.91.92.21.91.92.2-0.71.2
Bone: cortical apparent density1.82.44.02.01.9-1.8-1.6-1.5-0.5-1.3-1.5-1.3-1.6-1.6
Bone: cortical area1.52.24.40.71.2-1.2-1.8-1.8-2.0-1.5-1.8-0.80.2-2.1
Bone: cortical porosity0.70.81.50.90.9-0.9-1.0-1.0-0.7-1.2-1.0-1.00.0-0.7
Bone: cortical porosity0.30.31.0-0.00.2-0.4-0.6-0.6-1.0-0.9-0.6-0.40.8-0.1
Bone: cortical thickness5.48.913.83.23.4-3.1-3.3-3.2-2.1-2.8-3.2-2.3-1.9-3.7
Bone: cortical thickness2.53.05.12.32.2-1.8-1.7-1.7-0.5-1.4-1.6-1.3-1.7-2.0
Bone: cortical tissue density1.51.93.21.81.7-1.7-1.4-1.3-0.5-1.2-1.3-1.1-1.4-1.4
Condit. Reinf. active minus inactive responses0.70.81.8-0.5-0.70.90.91.01.01.11.01.3-0.20.7
Condit. Reinf. active-inactive response ratio0.10.10.40.60.5-0.3-0.4-0.30.0-0.4-0.30.1-0.3-0.2
Condit. Reinf. active responses0.91.12.1-0.4-0.71.01.11.11.41.41.11.5-0.50.7
Condit. Reinf. inactive responses0.91.12.90.1-0.30.71.11.11.71.51.11.1-1.10.4
Incentive salience index mean2.53.05.1-1.7-1.82.01.81.81.31.91.82.30.81.5
Condit. Reinf. lever presses4.45.98.6-2.4-2.62.92.52.51.82.82.52.71.32.1
Condit. Reinf. active minus inactive responses0.70.81.90.20.5-0.8-1.0-1.0-1.4-1.2-1.0-0.51.0-0.5
Condit. Reinf. active-inactive response ratio1.11.23.4-0.10.4-0.7-1.2-1.2-1.8-1.4-1.2-0.61.4-0.5
Condit. Reinf. active responses0.00.00.2-0.1-0.1-0.00.00.10.0-0.10.00.40.40.3
Condit. Reinf. inactive responses0.91.12.3-0.3-0.60.71.21.21.51.41.20.9-0.90.8
Condit. Reinf. lever presses0.30.30.9-0.1-0.40.60.60.60.70.30.70.90.30.6
Condit. Reinf. lever reinforcers received0.10.10.4-0.3-0.30.20.30.30.20.00.30.60.60.6
Conditioned reinforcement - actives0.60.62.70.50.4-0.3-0.7-0.7-0.7-1.6-0.6-0.41.1-0.1
Conditioned reinforcement - inactives1.71.95.51.21.4-1.4-1.6-1.5-1.1-2.3-1.3-1.1-0.2-1.3
Conditioned locomotion0.10.10.5-0.2-0.30.20.1-0.1-0.3-0.7-0.00.30.50.7
Patch foraging indifference point 0 sec1.42.33.51.81.9-1.9-1.4-1.3-0.4-1.4-1.3-1.3-1.9-1.5
Patch foraging indifference point AUC1.41.63.30.40.9-1.3-1.6-1.6-1.8-1.7-1.5-1.10.5-0.8
Delay disc. indifference point, 0s delay0.40.42.2-0.2-0.10.0-0.4-0.5-0.5-1.1-0.3-0.01.50.2
Delay disc. indifference point, 16s delay3.33.36.02.32.2-1.9-1.9-1.8-0.4-2.5-1.9-1.7-0.6-1.6
Delay disc. indifference point, 2s delay1.21.32.80.20.4-0.5-1.2-1.3-1.6-1.7-1.1-1.21.6-0.5
Delay disc. indifference point, 24s delay0.90.91.71.00.9-0.8-1.0-0.9-0.5-1.2-1.1-1.00.1-1.3
Delay disc. indifference point, 4s delay1.41.53.80.00.5-0.9-1.4-1.5-1.4-2.0-1.3-1.21.4-0.8
Delay disc. indifference point, 8s delay0.40.40.80.50.6-0.6-0.8-0.8-0.2-0.9-0.6-0.60.2-0.5
Indifference point function ln k0.81.11.9-1.0-1.21.41.11.20.61.01.11.00.80.8
Indifference point function log k0.81.11.9-1.0-1.21.41.11.20.61.01.11.00.80.8
Patch foraging total patch changes 0 sec1.93.14.72.12.2-2.1-1.7-1.6-0.5-1.7-1.6-1.4-2.0-1.8
Patch foraging total patch changes 12 sec2.22.84.12.02.0-2.0-1.8-1.7-0.7-2.0-1.7-1.5-1.3-1.3
Patch foraging total patch changes 18 sec2.53.26.82.52.3-2.2-1.5-1.50.0-1.5-1.4-1.3-2.6-1.2
Patch foraging total patch changes 24 sec1.51.85.12.21.8-1.6-0.8-0.70.9-1.0-0.5-0.5-2.3-0.7
Patch foraging total patch changes 6 sec2.43.56.12.52.4-2.3-1.8-1.7-0.5-1.8-1.7-1.4-2.1-1.6
Patch foraging time to switch 0 sec0.30.52.41.10.8-0.5-0.10.00.70.10.1-0.5-1.5-0.4
Patch foraging water rate 0 sec0.40.61.30.60.7-0.8-0.8-0.9-0.9-1.1-1.0-0.60.3-0.4
Patch foraging water rate 12 sec0.20.30.80.90.7-0.4-0.2-0.20.20.1-0.3-0.2-0.9-0.6
Patch foraging water rate 18 sec0.10.10.4-0.10.2-0.4-0.5-0.5-0.6-0.3-0.40.10.1-0.5
Patch foraging water rate 24 sec1.41.93.01.01.2-1.1-1.5-1.6-1.7-1.5-1.6-1.50.1-1.5
Patch foraging water rate 6 sec0.20.30.90.90.8-0.7-0.4-0.5-0.1-0.3-0.5-0.4-0.8-0.3
Seeking ratio, delayed vs. immediate footshock0.30.31.10.10.3-0.5-0.7-0.8-0.8-0.3-0.5-0.60.0-1.0
Distance traveled before self-admin0.40.41.0-1.0-0.80.70.50.40.00.50.40.90.60.5
Distance traveled after self-admin0.10.10.5-0.7-0.40.3-0.0-0.1-0.50.3-0.3-0.40.20.1
Extensor digitorum longus weight0.20.62.1-1.1-1.00.90.30.4-0.40.20.40.91.40.2
Bone: elastic displacement0.80.92.01.01.0-1.3-0.7-0.7-0.3-0.4-0.7-1.1-1.4-1.0
Bone: elastic work2.02.63.61.11.5-1.9-1.8-1.8-1.7-1.6-1.7-1.6-0.7-1.9
Bone: endosteal estimation1.22.712.0-2.8-1.80.9-0.2-0.2-2.4-0.2-0.20.23.50.3
Bone: endosteal perimeter2.24.611.8-3.3-2.82.41.51.4-0.51.21.41.63.41.8
Epididymis fat weight8.118.935.35.95.5-4.7-4.1-4.0-1.3-3.5-4.0-4.2-4.3-4.7
Delta time in closed arm before/after self-admin0.20.20.70.30.2-0.2-0.3-0.4-0.4-0.8-0.5-0.20.60.1
Delta time in open arm before/after self-admin0.20.21.00.10.3-0.4-0.3-0.1-0.10.2-0.2-0.2-1.0-0.6
Diff in mean of infusions in LGA sessions2.02.24.80.0-0.91.51.71.72.21.21.52.1-0.21.7
Delay discount exponential model param1.92.05.2-1.2-1.31.31.61.61.02.31.61.5-0.61.2
Extinction: sum of active levers before priming0.30.31.10.3-0.20.50.40.40.70.10.60.71.00.5
Active lever presses in extinction session 60.30.30.60.80.6-0.6-0.2-0.30.4-0.6-0.5-0.7-0.5-0.1
Bone: final force5.99.513.32.33.0-3.0-3.6-3.6-3.2-3.2-3.6-3.0-0.5-3.6
Bone: final moment5.28.412.32.12.7-2.8-3.4-3.4-3.0-2.9-3.3-2.8-0.6-3.5
Food consumed during 24 hour testing period0.20.21.2-1.0-0.4-0.2-0.2-0.2-1.10.1-0.2-0.20.40.0
Glucose5.48.214.3-3.7-3.63.52.52.50.62.12.52.53.82.7
Heart weight0.20.21.30.0-0.10.0-0.2-0.2-0.5-0.7-0.2-0.51.10.5
Delay discount hyperbolic model param1.71.84.8-0.9-1.11.21.61.51.12.21.51.5-0.81.0
Intermittent access intake day 1-15 change0.70.61.20.30.7-1.1-0.7-0.9-0.8-0.9-0.8-0.7-1.0-0.7
Intermittent access intake escalation0.10.10.3-0.6-0.1-0.3-0.1-0.2-0.5-0.3-0.2-0.1-0.4-0.0
Intermittent access intake escalation 21.21.24.3-2.1-1.51.00.90.8-0.10.90.70.90.70.9
Intermitt. access day 1 inactive lever presses0.30.31.7-0.7-0.60.50.00.0-0.5-0.50.1-0.01.3-0.1
Intermitt. access day 15 inactive lever presses2.12.34.10.71.2-1.3-1.7-1.7-2.0-1.7-1.6-1.5-0.2-2.0
Intermitt. access escalation Index2.01.83.3-0.8-1.21.31.61.81.81.21.61.2-0.11.1
Intermittent access day 1 total infusions0.10.20.50.1-0.20.30.30.50.70.20.60.6-0.30.2
Intermittent access day 15 total infusions0.10.10.50.20.1-0.20.1-0.00.2-0.20.10.3-0.70.1
Intermittent access terminal intake (last 3 days)0.10.10.60.40.3-0.4-0.4-0.4-0.2-0.7-0.3-0.1-0.2-0.2
Intermittent access total infusions0.10.10.20.40.3-0.2-0.1-0.2-0.0-0.4-0.10.2-0.3-0.1
Intermittent access day 1 locomotion0.30.40.7-0.8-0.80.50.50.70.50.60.70.8-0.10.3
Intermittent access day 15 total locomotion0.20.21.0-0.8-0.2-0.3-0.4-0.5-1.0-0.2-0.50.1-0.2-0.0
Intermittent access total locomotion0.10.20.7-0.8-0.3-0.3-0.3-0.3-0.80.1-0.30.1-0.3-0.2
Intermittent access standard deviation2.72.93.71.41.7-1.8-1.8-1.9-1.7-1.9-1.9-1.8-0.5-1.8
Left kidney weight2.67.314.31.12.1-2.7-3.1-3.1-3.8-2.6-3.0-3.30.0-2.9
Right kidney weight1.54.312.2-0.01.1-1.9-2.4-2.4-3.5-1.8-2.3-2.20.4-2.4
Cocaine induced anxiety3.64.15.5-2.2-2.22.12.22.21.72.32.22.20.31.9
Post-drug Anxiety1.41.62.4-1.3-1.41.61.41.40.91.21.31.20.71.2
Baseline Anxiety0.60.61.91.40.9-0.4-0.5-0.6-0.2-1.4-0.6-0.70.7-0.5
Tail length1.34.016.8-2.0-0.4-0.9-1.9-1.9-4.1-1.6-1.9-1.32.5-1.1
Length with tail1.55.619.1-1.20.5-1.7-2.6-2.6-4.4-1.8-2.6-2.71.7-2.1
Length without tail1.53.38.2-0.10.8-1.5-2.1-2.1-2.9-1.7-2.0-2.31.0-1.8
Times rat made contact with spout0.80.95.61.10.8-0.50.30.31.40.70.20.2-2.4-0.2
Lifetime Intake0.10.10.40.30.1-0.0-0.1-0.2-0.1-0.6-0.10.30.20.0
Liver weight, left0.30.42.2-1.5-0.80.2-0.10.1-1.00.80.0-0.30.5-0.2
Liver weight, right1.01.77.1-1.9-0.8-0.1-0.8-0.7-2.7-0.4-0.8-1.21.8-0.4
Locomotor activity0.60.94.3-2.1-1.20.30.10.2-1.50.50.1-0.01.20.3
Locomotor testing distance0.10.20.9-1.0-0.70.30.20.3-0.70.30.20.10.60.1
Locomotor testing rearing0.20.31.3-1.1-0.6-0.1-0.10.1-1.00.1-0.0-0.20.60.1
Locomotion in novel chamber0.50.60.90.20.5-0.8-0.9-0.9-0.8-0.8-0.9-0.9-0.4-0.7
Locomotion in novel chamber post-restriction0.60.81.10.80.9-0.9-1.0-1.0-0.7-0.8-1.0-1.1-0.3-0.8
Fecal boli incidents, locomotor time 10.50.61.3-0.3-0.60.80.90.90.81.10.90.7-0.20.3
Change in fecal boli incidents, locomotor task0.60.53.10.20.10.1-0.6-0.5-0.6-1.0-0.7-0.61.8-0.2
Time >=10cm from walls, locomotor time 10.40.41.5-1.1-0.70.40.10.1-0.8-0.1-0.0-0.11.20.2
Bouts of movement, locomotor time 11.61.72.5-1.5-1.41.11.51.41.41.61.21.5-0.01.1
Total resting periods, locomotor time 11.11.22.1-1.4-1.30.91.11.11.11.40.91.30.20.9
Rest time, locomotor task time 10.70.72.7-1.6-1.10.70.70.6-0.21.30.40.7-0.00.4
Distance moved, locomotor task time 11.01.11.71.21.2-1.1-1.2-1.1-0.9-1.3-1.1-1.1-0.1-0.9
Vertical activity count, locomotor time 10.80.81.71.01.0-1.1-0.8-0.7-0.7-1.3-0.8-1.0-0.1-0.6
Time >=10cm from walls, locomotor time 20.30.31.3-0.7-0.70.60.40.4-0.40.10.30.11.10.2
Bouts of movement, locomotor time 20.30.42.2-1.5-0.9-0.00.10.0-0.80.40.1-0.20.20.1
Total resting periods, locomotor time 20.70.73.6-1.9-1.30.40.50.4-0.50.70.50.30.60.5
Rest time, locomotor task time 22.52.88.0-2.8-2.31.71.61.60.11.81.51.41.01.3
Distance moved, locomotor task time 21.82.04.22.01.8-1.5-1.5-1.4-0.8-1.7-1.5-1.3-0.5-1.0
Vertical activity count, locomotor time 20.50.51.61.30.9-0.7-0.6-0.5-0.1-1.0-0.8-0.6-0.0-0.2
Light reinforcement 10.40.81.61.31.1-0.8-0.7-0.8-0.2-0.5-0.9-1.1-1.1-0.5
Light reinforcement 20.20.30.8-0.40.2-0.6-0.6-0.8-0.90.0-0.7-0.6-0.6-0.4
Bone: marrow area1.22.611.9-2.7-1.70.8-0.2-0.2-2.3-0.2-0.20.23.50.3
Bone: maximum diameter0.71.35.1-1.9-1.41.20.30.3-1.00.30.31.02.30.3
Bone: maximum force4.47.611.11.82.5-2.8-3.3-3.2-3.1-2.7-3.2-2.6-0.6-3.3
Bone: maximum moment3.86.610.11.52.3-2.6-3.0-3.0-3.0-2.4-3.0-2.4-0.5-3.2
Mean time between licks in bursts2.13.06.9-2.6-2.32.01.51.50.01.31.41.52.11.4
Mean num. licks in bursts1.72.08.11.61.6-1.5-0.7-0.80.30.2-0.9-1.4-2.8-1.6
Cd content in liver1.11.32.01.21.4-1.3-1.1-1.2-0.6-0.6-1.1-0.7-1.4-1.4
Co content in liver2.42.83.81.92.0-1.9-1.9-1.8-1.1-1.8-1.7-1.6-0.9-1.5
Cu content in liver1.11.34.51.10.30.31.01.02.11.11.10.5-2.00.6
Fe content in liver1.21.52.61.21.3-1.5-1.0-1.1-0.6-0.8-1.0-1.6-1.5-1.3
K content in liver0.30.31.1-0.1-0.30.60.30.30.4-0.10.40.61.10.7
Mg content in liver4.44.56.5-2.0-2.32.52.12.01.51.52.12.52.32.4
Mn content in liver5.66.311.3-3.1-3.12.82.32.20.71.82.22.23.42.8
Na content in liver0.20.20.50.60.5-0.0-0.4-0.5-0.2-0.7-0.4-0.30.3-0.4
Rb content in liver0.60.81.3-0.3-0.60.91.01.01.20.81.01.0-0.11.1
Se content in liver4.04.97.5-2.7-2.72.72.01.80.81.62.02.52.62.1
Sr content in liver0.30.31.5-0.6-0.40.3-0.4-0.4-0.8-0.5-0.3-0.41.2-0.0
Zn content in liver0.20.20.8-0.2-0.40.60.20.10.0-0.20.20.40.90.4
Bone: minimum diameter1.01.87.5-2.1-1.61.40.30.3-1.10.30.31.32.70.3
Time in familiar zone, hab. session 11.00.93.81.10.40.10.70.72.00.80.70.4-1.70.1
Time in novel zone, hab. session 10.60.62.0-1.2-0.6-0.2-0.3-0.3-1.4-0.4-0.3-0.31.30.5
Total zone transitions, hab. session 10.30.41.3-0.1-0.40.60.70.81.10.90.80.6-0.20.3
Total locomotion distance, hab. session 10.20.31.00.1-0.20.60.60.61.00.60.60.4-0.10.1
Locomotion velocity, hab. session 10.10.10.50.50.10.30.20.20.70.10.20.1-0.1-0.4
Time in familiar zone, hab. session 20.10.10.40.50.30.10.10.10.60.20.1-0.4-0.5-0.1
Time in novel zone, hab. session 20.20.20.8-0.10.2-0.9-0.4-0.4-0.7-0.1-0.40.0-0.6-0.3
Total zone transitions, hab. session 20.10.20.50.60.5-0.3-0.3-0.30.2-0.2-0.3-0.7-0.3-0.5
Total locomotion distance, hab. session 20.40.51.90.2-0.30.60.80.81.40.80.80.4-0.40.5
Locomotion velocity, hab. session 20.50.62.10.1-0.40.90.90.91.40.80.90.5-0.20.5
Novel to familiar place preference ratio0.10.20.40.50.5-0.5-0.3-0.3-0.0-0.3-0.3-0.0-0.6-0.2
Novelty place preference0.20.20.30.40.5-0.6-0.4-0.5-0.3-0.5-0.5-0.1-0.5-0.3
Time in novel zone, NPP test0.20.20.40.30.5-0.6-0.5-0.5-0.4-0.5-0.5-0.2-0.5-0.3
Total zone transitions, NPP test0.71.02.1-0.4-0.70.81.11.11.51.41.20.9-0.60.7
Total locomotion distance, NPP test0.40.62.00.3-0.20.40.80.81.40.90.80.7-1.00.4
Locomotion velocity, NPP test0.81.13.50.2-0.30.71.21.11.91.21.11.0-1.00.7
Intraocular pressure0.91.23.8-0.4-0.50.61.21.11.22.01.01.0-1.50.2
Delta distance traveled before/after self-admin1.01.12.30.50.8-1.1-1.1-1.0-1.2-0.9-1.2-1.5-0.5-1.1
Delta ambulatory time before/after self-admin0.20.31.1-0.20.1-0.4-0.4-0.3-0.8-0.4-0.6-1.1-0.1-0.4
Parametrial fat weight2.03.95.51.31.9-2.3-2.2-2.2-2.4-1.8-2.1-2.3-0.9-1.8
Pavlov. Cond. lever latency3.34.27.12.62.5-2.7-1.8-1.9-0.7-1.9-1.9-2.0-2.3-1.7
Pavlov. Cond. magazine entry latency3.24.26.7-2.6-2.52.52.02.00.92.22.01.81.61.8
Pavlov. Cond. change in total contacts0.80.83.2-1.4-1.11.20.20.2-0.70.40.30.41.8-0.0
Pavlov. Cond. index score4.35.59.4-2.9-2.93.12.22.20.92.32.22.32.31.9
Pavlov. Cond. latency score3.64.68.1-2.8-2.62.81.91.90.51.91.92.12.41.6
Pavlov. Cond. lever contacts2.73.16.0-2.3-2.22.51.41.40.11.51.51.62.51.1
Pavlov. Cond. magazine entry number3.34.16.12.22.3-2.5-2.1-2.1-1.3-2.3-2.1-1.9-1.4-1.7
Pavlov. Cond. intertrial magazine entries0.80.94.11.41.2-1.3-0.3-0.30.8-0.1-0.30.1-2.0-0.3
Pavlov. Cond. lever-magazine prob. diff.4.55.69.6-2.9-2.83.12.22.31.02.42.32.32.21.8
Pavlov. Cond. response bias4.45.38.5-2.7-2.72.92.22.31.12.42.32.22.01.9
Pavlov. Cond. lever latency0.10.10.3-0.10.0-0.1-0.3-0.4-0.5-0.4-0.4-0.40.4-0.1
Pavlov. Cond. magazine entry latency0.20.31.0-0.20.10.0-0.5-0.5-1.0-0.6-0.5-0.80.4-0.4
Pavlov. Cond. change in total contacts0.40.50.70.80.9-0.8-0.7-0.7-0.5-0.7-0.7-0.7-0.6-0.8
Pavlov. Cond. index score0.00.00.10.10.10.0-0.1-0.0-0.2-0.1-0.1-0.3-0.2-0.3
Pavlov. Cond. latency score0.10.10.20.20.3-0.1-0.3-0.3-0.4-0.3-0.3-0.5-0.1-0.5
Pavlov. Cond. lever contacts0.20.31.70.80.7-0.5-0.2-0.10.30.1-0.1-0.3-1.3-0.5
Pavlov. Cond. magazine entry number0.30.30.9-0.2-0.50.40.60.60.80.60.60.90.40.6
Pavlov. Cond. intertrial magazine entries2.63.54.6-2.0-2.22.02.01.91.31.81.92.01.41.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.10.10.0-0.1-0.1-0.2-0.0-0.1-0.3-0.2-0.3
Pavlov. Cond. response bias0.10.10.80.20.2-0.10.10.10.20.30.1-0.2-0.9-0.2
Time in closed arm before self-admin0.00.00.10.10.10.20.0-0.00.00.10.00.00.2-0.1
Time in closed arm after self-admin1.11.11.71.21.2-1.1-1.1-1.2-0.7-1.3-1.2-0.8-0.1-1.1
Time in open arm before self-admin0.60.71.7-1.3-1.10.50.70.90.50.80.90.8-0.10.8
Time in open arm after self-admin0.91.01.6-1.3-1.10.80.91.31.01.11.20.9-0.40.7
Bone: periosteal estimation0.91.96.8-1.2-0.3-0.3-1.2-1.3-2.6-1.1-1.2-0.42.2-1.1
Bone: periosteal perimeter0.60.94.5-1.4-0.80.5-0.3-0.4-1.5-0.3-0.30.32.1-0.2
Bone: post-yield work0.91.23.5-1.9-1.51.10.90.90.01.20.91.10.81.0
Progressive ratio test 1 active lever presses0.10.10.40.0-0.20.20.10.30.4-0.50.40.40.50.6
Progressive ratio test 1 breakpoint0.10.20.50.1-0.10.10.00.20.4-0.70.30.40.70.5
Progressive ratio test 1 inactive lever presses0.30.31.11.00.8-0.4-0.4-0.40.1-1.0-0.30.0-0.4-0.5
Progressive ratio test 2 active lever presses0.20.30.70.2-0.20.40.60.50.80.10.60.7-0.20.7
Progressive ratio test 2 breakpoint0.40.51.20.2-0.20.50.80.71.10.40.81.0-0.50.7
Progressive ratio test 2 inactive lever presses0.20.20.6-0.10.2-0.3-0.6-0.6-0.8-0.6-0.4-0.1-0.1-0.4
Incentive Sensitization - Responses0.30.30.7-0.0-0.30.60.70.60.80.60.70.7-0.30.7
Incentive Sensitization - Breakpoint0.50.50.8-0.1-0.40.70.80.70.90.80.80.8-0.40.7
Sum of active levers in priming session hrs 5-60.20.20.50.1-0.40.60.50.40.60.10.50.50.00.7
Progressive ratio4.34.97.51.31.9-2.5-2.4-2.7-2.7-2.3-2.3-2.5-0.7-2.2
Food seeking constrained by brief footshock0.00.00.1-0.1-0.1-0.10.10.1-0.20.40.2-0.0-0.3-0.1
Seeking ratio, punishment vs. effort3.64.46.9-1.1-1.82.42.32.62.42.22.32.30.62.1
Retroperitoneal fat weight0.41.21.90.71.0-1.2-1.3-1.2-1.1-1.0-1.2-1.4-0.3-1.1
Reaction time number correct0.81.23.01.71.4-1.2-0.8-0.9-0.1-1.1-0.9-1.1-0.9-1.0
Reaction time mean minus median2.73.612.1-3.5-2.61.71.61.60.22.51.71.40.81.2
Reaction time mean minus median AUC2.22.88.2-2.9-2.31.61.51.50.42.01.61.31.01.1
Reaction time num false alarms0.20.30.90.10.1-0.2-0.4-0.5-1.0-0.6-0.7-0.30.9-0.2
Reaction time num false alarms AUC0.40.51.50.10.2-0.3-0.6-0.7-1.2-0.9-0.9-0.51.2-0.3
Reaction time trials correct on left0.81.23.01.71.4-1.2-0.8-0.9-0.1-1.1-0.9-1.1-0.9-1.0
Reaction time trials on left0.81.12.61.61.4-1.2-0.8-0.8-0.2-1.1-0.9-1.1-0.8-0.9
Reaction time mean3.04.210.4-3.2-2.72.11.91.90.62.51.92.01.21.4
Reaction time mean AUC3.14.210.6-3.3-2.72.01.91.90.62.51.91.91.11.4
Median of all reaction times2.12.96.1-2.5-2.21.81.61.50.62.01.51.81.11.2
Reaction time omissions2.23.17.3-2.7-2.31.91.51.50.21.81.61.61.51.5
Reaction time false alarm rate0.40.53.2-0.9-0.70.5-0.0-0.0-0.9-0.3-0.20.21.80.5
Reaction time premature initiation rate1.21.62.50.91.1-0.9-1.5-1.6-1.6-1.5-1.3-1.30.4-1.4
Reaction time premature initiations2.33.24.61.81.8-1.6-2.0-2.1-1.7-2.1-1.8-1.90.0-1.9
Std. dev. reaction times2.63.612.1-3.5-2.71.81.51.50.12.21.61.51.31.2
Reaction time trials completed0.81.12.61.61.4-1.2-0.8-0.8-0.2-1.1-0.9-1.1-0.8-0.9
Reaction time trials AUC0.71.02.61.61.3-1.1-0.8-0.8-0.1-1.0-0.8-1.0-0.9-0.9
Run reversals in cocaine runway, females0.80.81.61.31.2-1.1-0.8-0.8-0.1-0.7-0.8-0.5-1.0-0.9
Run reversals in cocaine runway, males0.80.73.7-1.9-1.20.30.30.4-1.20.90.40.20.4-0.1
Latency to leave start box in cocaine runway0.20.21.30.30.10.1-0.3-0.1-0.3-0.6-0.3-0.31.1-0.1
Latency to leave start box in cocaine runway, F0.40.41.3-0.3-0.60.70.50.70.50.40.40.61.10.6
Latency to leave start box in cocaine runway, M1.81.82.51.21.3-1.3-1.5-1.5-1.2-1.5-1.6-1.5-0.2-1.3
Std. dev. time between licks in bursts2.22.67.8-2.3-2.11.71.11.1-0.30.51.01.32.81.7
Total sessions with >9 infusions0.20.20.90.20.10.0-0.3-0.3-0.2-0.9-0.30.30.80.3
Short access day 1 total inactive lever presses0.80.92.8-1.5-1.31.10.50.4-0.40.20.40.91.70.8
Short access day 10 total inactive lever presses0.20.20.6-0.8-0.60.30.30.3-0.10.20.40.30.50.1
Short access day 1 total infusions0.40.51.5-0.2-0.60.90.50.50.5-0.30.40.81.20.9
Short access day 10 total infusions0.10.10.30.40.3-0.1-0.4-0.4-0.3-0.6-0.50.10.5-0.0
Short access total infusions0.20.21.00.30.10.1-0.4-0.4-0.4-1.0-0.40.21.00.0
Short access day 1 locomotion2.83.04.9-0.9-1.52.01.91.92.11.41.72.20.82.0
Short access day 10 total locomotion1.01.15.7-1.2-1.21.20.60.5-0.20.00.30.72.40.9
Short access total locomotion0.60.61.9-0.6-0.80.90.50.50.4-0.00.41.01.40.9
One hour access (0.3 mA shock)0.40.51.0-0.5-0.70.60.80.80.80.30.91.0-0.20.6
Compulsive drug intake2.72.83.9-1.0-1.61.91.91.91.71.32.01.71.11.8
One hour access (shock baseline)0.30.40.8-0.30.3-0.7-0.6-0.6-0.9-0.4-0.6-0.4-0.8-0.8
Social response proportion0.30.31.4-0.7-0.70.60.20.3-0.1-0.10.3-0.11.20.3
Social responses0.20.21.40.1-0.00.1-0.3-0.2-0.4-0.7-0.2-0.61.2-0.2
Social time1.92.57.1-2.5-2.11.61.01.1-0.40.91.10.82.71.3
Soleus weight1.54.313.7-3.2-2.72.21.01.1-1.10.51.11.83.71.6
Bone: stiffness1.52.34.31.31.6-1.5-1.7-1.7-1.3-1.4-1.7-1.2-0.7-2.1
Tibialis anterior weight0.31.02.71.61.4-0.9-0.8-0.7-0.0-0.7-0.8-0.1-1.3-1.2
Time to tail flick, vehicle, before self-admin0.40.41.1-0.8-0.70.60.50.50.11.00.60.5-0.11.0
Time to tail flick, vehicle, after self-admin2.02.13.6-1.7-1.61.61.61.40.81.91.31.60.11.6
Time to tail flick, test, before self-admin0.20.20.40.50.6-0.6-0.5-0.20.1-0.3-0.3-0.6-0.6-0.3
Time to tail flick, test, after self-admin1.71.83.2-1.7-1.40.91.41.41.01.81.31.6-0.90.9
Delta time to tail flick, vehicle, before/after SA0.70.71.4-0.5-0.60.71.10.81.01.20.90.9-0.50.4
Delta time to tail flick, test, before/after SA1.00.91.9-0.7-0.70.71.11.00.91.40.91.3-0.80.7
Tibia length0.82.27.7-1.4-0.5-0.2-1.2-1.3-2.8-1.1-1.3-1.22.5-0.9
Ambulatory time before self-admin0.00.10.2-0.5-0.2-0.10.10.0-0.1-0.3-0.00.4-0.20.0
Ambulatory time after self-admin0.10.10.6-0.8-0.40.20.10.1-0.60.4-0.1-0.3-0.30.1
Bone: tissue strength4.14.05.41.31.8-2.2-2.3-2.2-2.3-2.1-2.2-2.3-0.5-1.9
Total heroin consumption0.10.10.4-0.2-0.1-0.20.10.10.1-0.10.10.6-0.40.1
Bone: trabecular number0.71.14.60.60.2-0.00.80.81.61.10.81.3-2.1-0.0
Bone: trabecular spacing2.02.66.40.00.6-0.7-1.7-1.7-2.5-1.9-1.7-2.21.7-1.0
Bone: trabecular thickness0.60.72.10.3-0.00.20.70.71.31.10.71.0-1.4-0.2
Bone: trabecular tissue density1.52.13.30.91.2-1.0-1.7-1.7-1.7-1.8-1.7-1.70.5-1.5
Water consumed over 24 hours0.10.20.6-0.5-0.40.30.20.3-0.1-0.10.30.30.70.8
Number of responses in last shaping day0.40.43.2-0.1-0.20.5-0.2-0.2-0.4-0.9-0.40.21.80.2