Flot1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Flot1 0.19 0.11 1.2e-03 0.01 0.03 0.01 0.01 1.0e-02 1.7e-04 2.7e-02 2.8e-02
2 NAcc gene expression Flot1 0.05 0.03 6.5e-05 0.01 0.03 0.01 0.02 3.3e-03 4.0e-05 4.0e-03 1.3e-04
3 Adipose alternative TSS XM_063279499.1 0.08 0.09 6.2e-05 0.04 0.03 0.04 0.04 7.4e-05 4.5e-04 4.6e-05 4.3e-05
4 Brain isoform ratio NM_022701.2 0.04 0.03 4.4e-03 0.01 0.01 0 0.01 3.1e-02 1.6e-02 2.3e-01 7.6e-02
5 Adipose alternative TSS NM_022701.2 0.03 0.02 2.5e-03 0.01 0.01 0.02 0.01 6.9e-03 1.6e-02 5.9e-03 1.8e-02
6 BLA gene expression Flot1 0.4 0.17 2.3e-15 0.18 0.22 0.21 0.22 4.3e-10 7.8e-12 3.5e-11 1.1e-11
7 Liver isoform ratio XM_006256024.5 0.24 0.13 0.0e+00 0.19 0.19 0.2 0.19 4.0e-21 3.9e-21 3.4e-21 4.2e-21
8 IC gene expression Flot1 0.15 0.08 1.1e-05 0.09 0.1 0.1 0.11 1.4e-04 3.6e-05 4.0e-05 3.3e-05
9 Liver alternative TSS XM_063279499.1 0.21 0.11 0.0e+00 0.17 0.18 0.18 0.18 6.4e-19 1.4e-19 1.1e-19 1.3e-19
10 pVTA gene expression Flot1 0.32 0.28 2.5e-05 0.05 0.04 0.06 0.06 7.6e-05 1.9e-04 6.6e-06 1.4e-05
11 Liver gene expression Flot1 0.36 0.13 0.0e+00 0.25 0.27 0.26 0.28 2.6e-27 2.1e-30 1.1e-28 3.7e-31
12 Liver isoform ratio NM_022701.2 0.08 0.05 2.6e-08 0.05 0.06 0.06 0.06 1.5e-06 1.9e-07 1.9e-07 1.4e-07
13 Liver alternative TSS NM_022701.2 0.2 0.11 0.0e+00 0.18 0.17 0.18 0.18 1.4e-19 6.3e-19 3.1e-19 3.8e-19
14 BLA intron excision ratio chr20_2932310_2932607 0.12 0.08 1.6e-04 0.05 0.05 0.04 0.05 1.2e-03 1.7e-03 5.7e-03 1.3e-03
15 Liver alternative TSS NM_022701.2 0.36 0.16 0.0e+00 0.31 0.31 0.32 0.32 2.0e-35 2.2e-35 1.0e-36 1.1e-36
16 Adipose alternative TSS NM_022701.2 0.03 0.02 6.4e-03 0.02 0.01 0 0.01 5.5e-03 5.8e-02 1.5e-01 2.7e-02
17 LHb gene expression Flot1 0.17 0.12 7.1e-03 0.04 0.09 0.06 0.05 4.0e-02 4.3e-03 1.4e-02 2.5e-02
18 Adipose gene expression Flot1 0.21 0.11 0.0e+00 0.21 0.22 0.23 0.22 2.2e-23 1.2e-24 3.6e-25 1.5e-24
19 Liver alternative TSS XM_063279497.1 0.35 0.11 0.0e+00 0.3 0.31 0.31 0.32 5.0e-34 8.4e-35 1.8e-34 9.5e-36
20 Liver isoform ratio XM_063279497.1 0.03 0.02 3.8e-03 0.02 0 0.01 0.01 1.2e-03 1.5e-01 1.7e-02 1.3e-02
21 IL gene expression Flot1 0.74 0.15 9.1e-12 0.25 0.33 0.32 0.32 9.1e-07 1.0e-08 1.3e-08 1.3e-08
22 Liver alternative TSS XM_063279499.1 0.05 0.04 1.7e-05 0.03 0.03 0.03 0.03 2.3e-04 2.1e-04 5.2e-04 7.9e-04
23 Adipose alternative TSS XM_063279497.1 0.05 0.04 5.9e-05 0.04 0.03 0.04 0.04 5.3e-05 9.8e-05 5.7e-05 3.7e-05
24 Brain gene expression Flot1 0.43 0.14 0.0e+00 0.16 0.2 0.2 0.19 6.1e-15 2.5e-18 7.6e-19 1.6e-17
25 OFC gene expression Flot1 0.43 0.15 1.4e-08 0.26 0.28 0.3 0.3 7.1e-07 2.5e-07 8.7e-08 6.7e-08
26 PL gene expression Flot1 0.23 0.08 0.0e+00 0.28 0.27 0.27 0.27 3.0e-30 2.0e-29 4.9e-29 5.5e-30

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.61.14.3-0.71.6-1.91.01.90.20.60.2-0.60.0-0.3-0.70.8-1.50.51.7-0.3-1.4-0.8-1.0-0.60.5-2.1-0.7-0.7-0.8
Area under the delay curve1.21.42.7-0.5-0.21.30.4-1.31.0-1.40.91.10.81.21.5-1.41.1-1.1-1.61.21.61.41.01.4-1.31.21.11.01.5
BMI with tail1.86.19.3-1.91.40.82.2-0.92.8-2.72.92.93.02.92.7-2.52.2-2.9-1.92.92.32.62.52.7-2.81.12.83.02.7
BMI without tail3.29.713.8-1.10.52.41.9-2.43.0-3.63.23.62.83.63.7-3.53.2-3.5-3.43.43.53.63.43.4-3.42.03.23.53.3
Body weight4.419.236.32.4-2.35.60.1-5.72.4-4.22.84.62.54.34.7-4.66.0-4.5-5.93.85.85.04.53.9-4.15.24.24.84.4
Weight adjusted by age1.42.26.60.9-1.42.4-0.6-2.50.5-1.20.21.20.71.31.9-1.72.0-1.1-2.21.01.91.40.71.0-1.12.61.31.21.1
Bone surface0.10.20.90.9-0.80.8-0.6-0.7-0.4-0.1-0.3-0.0-0.5-0.10.1-0.20.60.0-0.5-0.20.10.1-0.1-0.10.10.3-0.1-0.00.1
Bone volume0.10.10.30.10.20.10.4-0.10.4-0.50.50.40.20.50.5-0.50.4-0.4-0.30.40.20.50.20.4-0.4-0.20.30.40.4
Breakpoint value in progressive ratio session0.30.30.80.2-0.2-0.5-0.40.6-0.60.6-0.4-0.5-0.5-0.4-0.60.7-0.70.50.6-0.7-0.4-0.6-0.4-0.70.7-0.5-0.9-0.7-0.9
Number of licking bursts0.71.12.40.1-1.20.2-1.5-0.1-1.41.1-1.6-1.2-1.2-1.5-1.01.0-0.51.30.4-1.3-0.8-0.9-1.0-1.01.20.6-1.1-1.1-1.0
Context. condit. distance diff. score8.19.713.62.5-1.5-1.0-2.61.4-3.53.5-3.5-3.5-3.6-3.7-3.53.4-2.63.52.4-3.6-3.1-3.4-3.3-3.63.6-1.9-3.7-3.4-3.5
Locomotion velocity, session 10.60.71.01.0-0.6-0.1-0.80.2-1.01.0-0.9-0.9-0.9-0.9-0.90.9-0.50.90.5-0.9-0.7-0.9-1.0-0.90.9-0.2-0.9-0.7-0.8
Locomotion distance, session 10.30.42.0-1.41.3-1.21.01.00.7-0.10.60.10.80.20.1-0.0-0.9-0.10.80.3-0.40.00.00.2-0.2-0.70.10.1-0.1
Locomotion velocity, session 20.10.10.30.5-0.50.2-0.5-0.1-0.50.5-0.5-0.4-0.4-0.5-0.30.40.00.40.0-0.4-0.1-0.3-0.3-0.40.40.2-0.3-0.3-0.3
Locomotion distance, session 20.10.20.6-0.30.5-0.70.30.7-0.10.5-0.1-0.50.0-0.3-0.40.4-0.80.50.7-0.2-0.5-0.5-0.4-0.40.3-0.5-0.4-0.5-0.5
Locomotion velocity, session 30.40.41.0-0.90.9-0.41.00.30.9-0.70.90.70.80.80.6-0.60.0-0.7-0.00.80.20.60.60.7-0.7-0.40.60.60.6
Locomotion distance, session 30.80.82.5-0.10.7-1.20.31.2-0.40.8-0.4-0.8-0.6-0.7-0.90.9-1.30.81.2-0.7-1.2-0.9-0.9-0.90.8-1.6-1.0-1.0-1.0
Stereotopy head waving bouts, day 30.91.14.01.2-1.72.0-1.2-1.8-0.3-0.5-0.30.5-0.10.30.7-0.71.6-0.5-1.70.21.30.80.70.4-0.32.00.50.60.7
Stereotopy head waving duration, day 30.70.83.30.7-1.21.6-0.8-1.5-0.1-0.5-0.10.50.20.40.7-0.81.3-0.5-1.40.31.20.80.60.5-0.41.80.60.70.7
Locomotion velocity, session 73.43.85.80.50.6-1.8-0.32.0-1.42.2-1.5-2.1-1.4-2.0-2.32.3-2.22.02.3-1.9-2.4-2.3-2.2-2.12.0-2.3-2.1-2.0-2.2
Locomotion distance, session 72.43.06.4-0.31.2-2.20.32.2-0.91.7-0.9-1.7-1.0-1.5-1.91.9-2.21.62.4-1.4-2.4-1.9-1.9-1.61.5-2.5-1.7-1.7-1.9
Stereotopy head waving bouts, day 72.12.34.50.4-0.81.9-0.1-1.90.9-1.40.91.51.01.51.6-1.62.0-1.5-2.11.32.11.61.51.4-1.42.11.61.71.7
Stereotopy head waving duration, day 72.02.44.60.5-0.92.0-0.1-1.90.9-1.50.91.61.01.51.7-1.72.1-1.6-2.21.32.11.71.61.4-1.42.11.61.71.6
Locomotion velocity, session 83.03.69.22.9-2.91.6-3.0-1.4-2.61.8-2.7-1.8-2.4-2.1-1.51.40.21.8-0.3-2.1-0.4-1.4-1.4-1.81.91.3-1.7-1.5-1.5
Locomotion distance, session 84.26.18.32.0-1.0-0.9-1.91.2-2.72.8-2.8-2.9-2.7-2.9-2.82.7-2.12.82.0-2.8-2.5-2.7-2.7-2.82.8-1.6-2.9-2.7-2.8
Degree of sensitization distance0.90.91.70.7-0.80.0-1.20.0-1.21.1-1.3-1.1-1.1-1.3-1.11.0-0.31.10.5-1.1-0.8-1.0-1.1-1.01.10.1-0.9-0.9-0.9
Degree of sensitization stereotypy1.01.11.8-0.1-0.31.10.2-1.10.8-1.00.81.10.91.11.2-1.11.2-1.1-1.31.01.41.21.11.1-1.01.31.21.21.2
Conditioned locomotion0.40.41.50.7-0.91.0-0.6-1.1-0.0-0.4-0.10.40.10.30.6-0.61.0-0.3-0.90.30.90.50.40.3-0.31.20.40.40.5
Cocaine response after cond. corrected0.40.41.0-0.70.4-0.90.00.9-0.30.6-0.4-0.6-0.2-0.7-0.60.6-0.90.71.0-0.5-1.0-0.7-0.7-0.50.6-0.6-0.6-0.6-0.7
Cocaine response after cond. not corrected0.20.21.00.7-1.00.6-0.9-0.6-0.60.3-0.6-0.3-0.5-0.5-0.20.20.20.4-0.3-0.40.0-0.2-0.2-0.30.40.7-0.3-0.2-0.2
Cocaine response before conditioning2.63.19.32.1-2.33.0-1.2-3.00.0-1.20.31.30.01.11.5-1.52.6-1.2-2.80.82.41.51.61.0-1.12.61.21.51.5
Saline control response2.63.45.7-1.01.20.41.9-0.62.2-2.12.42.22.12.42.1-2.01.3-2.2-1.22.21.62.01.92.0-2.20.22.12.02.1
Bone: connectivity density1.62.54.70.00.9-1.90.02.0-1.01.6-1.0-1.6-0.9-1.4-1.71.7-2.01.62.2-1.4-2.1-1.7-1.8-1.51.5-2.1-1.7-1.6-1.7
Bone: cortical apparent density1.11.53.1-1.51.6-0.51.80.41.7-1.21.51.31.61.51.2-1.10.3-1.3-0.31.50.81.11.01.3-1.4-0.21.31.01.1
Bone: cortical area1.21.83.30.4-0.61.60.1-1.60.8-1.40.81.40.71.21.5-1.61.8-1.4-1.81.21.71.51.21.3-1.31.51.41.41.5
Bone: cortical porosity0.50.60.9-0.5-0.20.70.2-0.60.6-0.90.70.80.80.70.9-1.00.9-0.8-1.00.80.80.80.90.9-0.80.80.80.70.8
Bone: cortical porosity0.30.31.10.2-0.81.1-0.5-0.9-0.0-0.40.10.40.20.20.5-0.61.0-0.4-1.00.30.70.50.50.4-0.31.00.40.40.5
Bone: cortical thickness4.47.310.4-2.21.70.72.6-0.93.2-3.13.13.13.03.23.1-3.01.9-3.0-2.03.22.52.92.73.1-3.11.13.22.83.0
Bone: cortical thickness2.73.25.6-2.02.1-0.52.40.22.4-1.72.21.92.32.31.8-1.60.8-2.0-0.62.21.21.61.51.9-2.00.02.12.01.8
Bone: cortical tissue density0.91.22.6-1.41.4-0.51.60.41.5-1.11.41.11.41.41.1-1.00.2-1.1-0.21.30.70.90.91.1-1.2-0.21.20.90.9
Condit. Reinf. active minus inactive responses0.60.71.30.30.2-0.9-0.20.9-0.60.9-0.7-1.0-0.6-0.8-0.90.9-1.11.01.0-0.8-1.0-1.0-1.0-0.90.8-0.8-0.9-1.0-0.9
Condit. Reinf. active-inactive response ratio0.10.20.5-0.70.6-0.30.60.20.5-0.30.50.30.70.40.3-0.2-0.0-0.30.00.40.10.30.20.4-0.40.10.50.40.4
Condit. Reinf. active responses1.01.22.70.30.6-1.30.11.3-0.61.2-0.6-1.2-0.7-0.9-1.21.2-1.61.21.4-0.9-1.3-1.3-1.2-1.11.0-1.5-1.1-1.3-1.1
Condit. Reinf. inactive responses1.31.65.6-0.31.4-1.90.82.0-0.21.0-0.2-1.1-0.4-0.7-1.11.1-2.11.01.8-0.7-1.6-1.2-1.1-0.90.8-2.4-1.1-1.2-1.2
Incentive salience index mean2.22.73.91.5-0.8-0.6-1.30.7-1.81.9-1.8-1.9-1.7-1.9-1.81.8-1.52.01.3-1.8-1.6-1.8-1.8-1.91.8-0.8-1.8-1.9-1.7
Condit. Reinf. lever presses4.36.08.02.4-1.4-0.6-2.20.8-2.82.8-2.8-2.8-2.8-2.8-2.72.6-1.92.81.8-2.8-2.3-2.7-2.7-2.82.8-1.1-2.8-2.6-2.6
Condit. Reinf. active minus inactive responses0.50.72.30.2-0.91.4-0.4-1.30.2-0.60.20.50.20.40.8-0.81.1-0.5-1.30.51.20.70.60.7-0.61.50.80.50.9
Condit. Reinf. active-inactive response ratio1.21.45.00.4-1.62.1-0.9-1.90.0-0.70.00.70.10.41.0-1.01.6-0.7-1.90.61.61.00.90.8-0.72.20.90.71.1
Condit. Reinf. active responses0.10.10.30.3-0.20.1-0.3-0.0-0.40.4-0.3-0.5-0.3-0.4-0.30.2-0.30.50.1-0.3-0.2-0.4-0.6-0.30.30.0-0.2-0.5-0.1
Condit. Reinf. inactive responses1.01.33.30.30.9-1.50.31.5-0.61.1-0.5-1.2-0.5-0.7-1.11.1-1.61.11.6-0.9-1.5-1.3-1.3-1.11.0-1.8-1.1-1.1-1.2
Condit. Reinf. lever presses0.60.81.60.10.1-0.7-0.30.7-0.81.1-0.8-1.1-0.7-0.9-1.01.0-1.11.01.0-0.9-1.0-1.0-1.3-0.90.9-0.7-0.9-1.0-0.9
Condit. Reinf. lever reinforcers received0.20.20.60.3-0.30.0-0.50.1-0.60.6-0.5-0.8-0.5-0.6-0.50.4-0.50.70.2-0.5-0.3-0.5-0.7-0.50.5-0.1-0.5-0.7-0.4
Conditioned reinforcement - actives1.11.94.6-0.60.30.51.0-0.31.4-1.91.71.50.41.11.7-2.11.1-1.6-1.21.41.51.71.91.5-1.5-0.31.21.12.0
Conditioned reinforcement - inactives1.31.94.2-1.00.50.61.2-0.51.5-1.71.61.30.81.41.5-2.00.9-1.4-1.31.61.71.71.91.7-1.7-0.01.21.11.6
Conditioned locomotion0.10.10.50.1-0.50.3-0.1-0.30.1-0.40.60.1-0.4-0.10.2-0.60.3-0.1-0.30.20.50.10.60.4-0.3-0.30.2-0.30.7
Patch foraging indifference point 0 sec1.12.03.5-1.71.6-0.61.90.51.9-1.61.61.61.81.81.6-1.50.6-1.6-0.51.60.91.51.51.5-1.5-0.41.11.50.8
Patch foraging indifference point AUC0.71.02.5-0.0-0.51.5-0.0-1.60.6-0.80.60.80.30.90.9-0.91.4-0.7-1.40.91.11.00.71.1-1.01.31.20.81.3
Delay disc. indifference point, 0s delay0.30.31.20.5-0.81.1-0.5-1.1-0.1-0.4-0.10.2-0.20.20.8-0.70.5-0.1-0.80.10.70.40.50.3-0.21.00.10.00.4
Delay disc. indifference point, 16s delay2.93.26.6-2.61.30.31.9-0.32.2-2.12.11.82.11.91.9-1.90.8-1.8-1.42.21.62.01.62.2-2.10.41.91.52.1
Delay disc. indifference point, 2s delay1.11.23.80.1-1.01.6-0.5-1.80.3-1.10.10.90.30.71.3-1.31.3-0.8-1.60.71.51.21.30.9-0.82.00.70.90.9
Delay disc. indifference point, 24s delay0.50.61.5-1.20.40.10.6-0.10.8-0.90.60.90.80.70.6-0.70.5-1.0-0.60.90.80.90.61.0-0.90.40.80.80.7
Delay disc. indifference point, 4s delay1.71.84.91.0-1.32.1-0.5-2.20.4-1.20.71.00.41.11.5-1.51.6-0.8-2.10.91.91.51.21.0-1.12.01.01.01.6
Delay disc. indifference point, 8s delay0.20.30.6-0.30.10.40.3-0.50.6-0.70.40.50.30.70.8-0.60.5-0.5-0.70.60.70.40.30.7-0.60.30.50.40.7
Indifference point function ln k0.30.61.20.6-0.6-0.3-0.90.4-1.00.9-0.9-0.8-0.7-1.1-0.80.9-0.30.80.5-1.0-0.6-0.9-0.8-0.91.0-0.1-0.7-0.8-0.7
Indifference point function log k0.30.61.20.6-0.6-0.3-0.90.4-1.00.9-0.9-0.8-0.7-1.1-0.80.9-0.30.80.5-1.0-0.6-0.9-0.8-0.91.0-0.1-0.7-0.8-0.7
Patch foraging total patch changes 0 sec1.42.74.6-2.01.8-0.52.10.42.1-1.91.91.92.02.01.8-1.70.8-1.8-0.71.91.01.71.61.8-1.8-0.31.41.71.1
Patch foraging total patch changes 12 sec1.82.44.0-2.01.50.11.9-0.22.0-1.71.71.71.81.81.7-1.60.8-1.7-0.81.81.01.51.51.8-1.80.21.51.61.3
Patch foraging total patch changes 18 sec1.62.56.8-2.52.6-1.02.60.82.2-1.42.01.51.91.91.3-1.00.0-1.50.01.80.41.31.01.7-1.7-1.01.41.31.1
Patch foraging total patch changes 24 sec1.12.07.6-2.62.8-1.82.61.61.9-0.91.71.01.61.40.7-0.6-0.7-1.10.81.3-0.30.60.31.1-1.1-1.60.70.80.3
Patch foraging total patch changes 6 sec2.03.06.1-2.52.2-0.52.40.22.4-1.92.11.92.22.21.6-1.70.7-1.8-0.62.11.01.71.42.0-2.0-0.21.71.91.2
Patch foraging time to switch 0 sec0.20.42.0-1.11.4-1.01.20.90.8-0.30.70.30.70.50.2-0.2-0.6-0.30.70.4-0.3-0.00.10.3-0.3-0.90.20.10.0
Patch foraging water rate 0 sec0.40.81.5-0.90.10.50.4-0.60.8-0.80.71.01.20.80.9-0.71.0-1.2-0.91.01.01.10.51.0-1.01.21.21.21.1
Patch foraging water rate 12 sec0.20.41.2-1.11.0-0.81.00.70.8-0.30.80.30.90.40.3-0.3-0.4-0.30.30.6-0.00.4-0.00.5-0.6-0.50.50.10.3
Patch foraging water rate 18 sec0.10.20.70.8-0.40.6-0.1-0.50.1-0.20.20.30.20.50.3-0.20.4-0.4-0.60.30.80.6-0.10.2-0.30.40.30.20.4
Patch foraging water rate 24 sec1.31.83.4-0.30.10.90.7-1.11.3-1.21.31.61.41.51.2-1.11.6-1.6-1.31.51.61.40.81.5-1.51.21.81.71.8
Patch foraging water rate 6 sec0.30.51.8-1.31.0-0.51.00.30.9-0.40.80.61.00.60.4-0.3-0.1-0.70.20.80.10.6-0.00.7-0.7-0.20.90.60.8
Seeking ratio, delayed vs. immediate footshock0.20.30.90.4-0.40.4-0.2-0.50.3-0.40.10.40.60.80.8-0.30.4-0.5-0.60.40.90.60.70.3-0.41.00.30.50.5
Distance traveled before self-admin0.50.63.92.0-1.41.2-1.1-1.1-0.90.2-0.7-0.5-1.4-0.5-0.2-0.10.40.5-0.5-0.60.2-0.5-0.1-0.50.50.5-0.6-0.7-0.5
Distance traveled after self-admin0.60.82.61.3-1.31.4-0.9-1.5-0.2-0.8-0.10.7-0.40.50.7-0.91.3-0.5-1.10.20.80.81.00.3-0.31.60.20.70.0
Extensor digitorum longus weight0.10.42.21.5-1.10.7-1.1-0.5-1.00.3-0.6-0.4-1.1-0.7-0.30.20.30.5-0.2-0.7-0.3-0.3-0.4-0.60.60.0-0.6-0.4-0.4
Bone: elastic displacement0.70.81.4-1.00.8-0.11.10.01.1-1.01.11.11.21.20.9-0.90.4-1.1-0.41.00.71.00.91.0-1.00.20.91.00.8
Bone: elastic work2.12.83.8-0.70.11.20.8-1.31.5-1.91.51.91.71.81.9-1.91.8-1.9-1.71.71.92.01.71.8-1.81.61.81.91.8
Bone: endosteal estimation2.04.318.54.1-4.33.7-3.6-3.4-2.20.4-1.9-0.5-2.2-1.0-0.1-0.02.40.5-2.3-1.21.20.10.1-0.70.82.9-0.6-0.10.0
Bone: endosteal perimeter2.34.914.63.8-3.62.0-3.6-1.6-3.11.9-2.8-2.0-3.0-2.4-1.71.60.41.9-0.4-2.5-0.7-1.5-1.6-2.22.21.1-2.1-1.5-1.6
Epididymis fat weight6.923.750.5-7.16.3-2.26.91.86.6-4.86.35.16.65.64.5-4.01.1-5.2-1.05.72.74.24.25.2-5.3-0.94.84.74.2
Delta time in closed arm before/after self-admin0.50.41.4-0.80.00.70.2-0.80.6-0.40.40.50.80.60.5-0.40.7-0.5-0.70.60.60.60.60.7-0.61.20.70.80.6
Delta time in open arm before/after self-admin0.30.32.21.5-0.40.5-0.0-0.60.0-0.60.50.6-0.60.20.6-0.80.5-0.6-0.50.30.70.40.10.2-0.3-0.30.20.20.5
Diff in mean of infusions in LGA sessions2.83.59.3-1.31.0-2.70.23.0-0.91.2-0.9-1.7-1.3-1.7-1.91.6-2.61.72.3-1.5-2.2-2.0-0.9-1.41.6-2.9-2.0-2.4-1.9
Delay discount exponential model param1.31.42.80.50.3-1.3-0.31.4-0.91.3-0.9-1.1-0.8-1.2-1.41.3-1.11.11.7-1.2-1.6-1.4-0.9-1.41.3-1.3-1.1-1.1-1.5
Extinction: sum of active levers before priming0.40.51.1-1.1-0.1-0.7-0.40.6-0.60.5-0.6-0.7-0.2-0.7-0.70.7-0.80.80.6-0.8-0.6-0.5-0.8-0.60.8-0.2-0.8-1.0-0.9
Active lever presses in extinction session 60.40.41.4-1.11.2-0.91.00.70.7-0.60.60.50.70.50.3-0.6-0.5-0.50.40.4-0.20.20.10.4-0.4-0.70.10.4-0.1
Bone: final force5.28.411.7-0.90.32.21.5-2.32.7-3.32.73.42.63.23.4-3.43.1-3.4-3.13.13.23.32.93.1-3.12.33.33.43.2
Bone: final moment4.57.210.1-0.60.22.11.3-2.22.4-3.12.53.12.32.93.2-3.12.9-3.1-3.02.83.03.12.72.9-2.92.13.03.13.0
Food consumed during 24 hour testing period0.50.64.42.1-1.31.5-0.9-1.4-0.5-0.1-0.30.2-0.70.10.2-0.21.2-0.2-1.1-0.10.80.20.0-0.1-0.00.90.10.30.4
Glucose4.67.213.83.7-3.21.1-3.6-0.7-3.62.9-3.5-2.9-3.5-3.1-2.62.5-0.82.90.6-3.1-1.5-2.6-2.5-2.92.90.5-2.8-2.8-2.4
Heart weight1.52.44.2-1.1-0.41.00.2-1.01.2-2.01.01.91.21.31.8-1.92.1-1.8-1.71.41.61.71.91.7-1.51.71.81.81.7
Delay discount hyperbolic model param1.41.52.80.50.3-1.4-0.31.5-1.01.3-0.9-1.2-0.9-1.2-1.51.4-1.21.11.7-1.3-1.7-1.4-1.0-1.41.3-1.4-1.2-1.1-1.5
Intermittent access intake day 1-15 change0.00.10.50.70.0-0.1-0.10.1-0.30.4-0.3-0.3-0.2-0.3-0.00.3-0.40.20.4-0.2-0.3-0.3-0.5-0.40.20.0-0.1-0.1-0.3
Intermittent access intake escalation0.00.10.40.60.40.00.4-0.10.3-0.20.30.20.40.40.5-0.2-0.1-0.40.00.40.20.2-0.00.1-0.30.10.30.40.1
Intermittent access intake escalation 20.50.64.82.2-0.90.6-1.0-0.7-1.00.7-0.9-0.6-0.6-0.6-0.30.4-0.20.50.0-0.7-0.2-0.6-0.9-0.80.60.7-0.4-0.2-0.5
Intermitt. access day 1 inactive lever presses0.10.52.40.5-1.61.0-1.3-0.9-0.70.5-0.9-0.5-0.7-0.7-0.30.40.80.5-0.6-0.40.30.2-0.3-0.10.31.0-0.2-0.2-0.2
Intermitt. access day 15 inactive lever presses0.51.02.30.4-0.61.3-0.1-1.30.5-0.70.70.90.60.81.0-0.81.4-1.0-1.30.91.21.20.70.9-0.91.51.11.31.2
Intermitt. access escalation Index2.33.34.60.6-0.0-1.6-0.81.5-1.61.9-1.5-1.9-1.9-1.9-2.12.0-2.11.92.1-1.9-2.1-1.9-2.0-1.91.9-2.0-2.1-2.0-1.8
Intermittent access day 1 total infusions0.40.63.5-0.90.8-1.00.91.20.6-0.81.10.5-0.40.20.3-0.7-0.6-0.40.20.30.20.51.50.4-0.3-1.9-0.3-0.30.2
Intermittent access day 15 total infusions0.30.52.0-0.10.7-0.40.90.50.8-0.91.10.70.10.60.8-0.9-0.3-0.7-0.20.60.60.71.40.5-0.6-1.00.10.20.6
Intermittent access terminal intake (last 3 days)0.70.92.7-0.70.7-0.11.00.21.1-1.31.31.00.40.81.1-1.4-0.0-1.0-0.51.00.81.11.61.0-1.0-0.60.70.61.0
Intermittent access total infusions0.50.62.2-0.30.5-0.20.80.30.8-1.21.20.8-0.20.60.9-1.2-0.0-0.9-0.50.70.70.91.50.7-0.8-1.10.30.30.8
Intermittent access day 1 locomotion0.10.21.00.6-0.1-0.30.00.3-0.2-0.20.50.0-0.5-0.1-0.1-0.1-0.60.10.3-0.30.1-0.10.7-0.30.2-1.0-0.7-0.60.0
Intermittent access day 15 total locomotion0.61.02.91.6-1.01.5-0.2-1.20.3-0.91.10.7-0.50.51.1-1.21.0-0.8-1.50.61.51.01.40.8-0.90.20.60.61.7
Intermittent access total locomotion0.80.92.21.4-0.71.1-0.0-0.90.3-1.01.20.8-0.30.61.1-1.20.8-0.9-1.30.61.51.11.40.7-0.8-0.10.50.51.4
Intermittent access standard deviation1.53.25.3-0.80.50.91.3-1.01.9-2.21.92.11.62.02.2-2.31.4-2.2-1.62.01.91.82.22.0-2.01.02.01.91.9
Left kidney weight3.516.327.41.0-1.14.11.0-4.32.9-4.23.44.53.04.24.6-4.35.2-4.5-4.93.95.04.24.33.9-4.04.04.44.74.7
Right kidney weight3.616.427.62.0-1.64.60.6-4.72.6-4.23.14.32.54.34.7-4.55.3-4.2-5.23.65.24.54.53.6-3.94.14.14.44.6
Cocaine induced anxiety1.01.42.41.4-0.9-0.3-1.20.4-1.51.5-1.4-1.3-1.3-1.3-1.31.5-0.51.10.7-1.4-0.8-1.0-1.6-1.31.3-0.3-1.3-1.3-1.4
Post-drug Anxiety0.60.72.1-0.0-0.1-0.4-0.70.3-0.81.1-1.0-0.9-0.1-0.8-0.71.2-0.50.80.6-0.9-0.8-1.0-1.5-0.91.00.3-0.8-0.8-1.3
Baseline Anxiety0.70.88.9-3.01.6-1.21.00.90.8-0.30.30.21.80.20.4-0.2-0.8-0.00.80.4-0.7-0.3-0.20.3-0.20.10.40.1-0.2
Tail length2.49.432.74.7-4.45.7-2.6-5.5-0.5-1.9-0.01.8-0.71.52.5-2.44.6-1.6-4.81.04.02.72.41.3-1.44.61.42.02.0
Length with tail3.314.447.56.0-5.36.9-3.1-6.7-0.5-2.30.12.4-0.62.03.0-3.05.7-2.2-5.81.34.93.43.01.6-1.85.72.12.82.7
Length without tail3.09.624.23.4-3.34.9-1.6-4.90.4-2.40.82.60.72.22.9-3.04.6-2.5-4.41.74.13.03.01.9-2.14.82.63.02.9
Times rat made contact with spout0.91.04.5-1.52.1-1.91.61.70.9-0.10.80.20.80.4-0.20.2-1.2-0.31.40.3-1.0-0.1-0.10.1-0.2-1.80.10.2-0.2
Lifetime Intake0.70.93.8-0.20.30.20.8-0.00.9-1.51.21.1-0.30.81.3-1.60.2-1.0-0.80.81.11.12.00.9-0.9-0.90.30.40.8
Liver weight, left1.62.615.23.9-3.12.3-2.7-2.1-2.10.8-1.7-0.7-2.1-1.1-0.50.41.10.8-1.0-1.40.4-0.4-0.3-1.31.21.5-1.0-0.4-0.5
Liver weight, right1.93.314.23.8-3.43.5-2.6-3.2-1.4-0.3-1.10.3-1.5-0.10.7-0.92.3-0.3-2.4-0.51.70.60.8-0.30.22.6-0.20.40.3
Locomotor activity1.62.413.03.6-2.72.7-2.4-2.8-1.70.9-1.6-0.7-1.6-0.6-0.30.41.50.5-1.2-1.00.5-0.5-0.9-0.90.82.1-0.30.1-0.2
Locomotor testing distance0.51.03.01.7-1.51.4-1.5-1.5-1.21.0-1.3-0.7-1.1-0.7-0.50.60.60.7-0.4-0.8-0.2-0.7-1.2-0.80.81.2-0.3-0.3-0.4
Locomotor testing rearing0.40.73.71.9-1.51.6-1.2-1.6-0.90.4-0.7-0.1-0.7-0.3-0.10.20.90.1-0.9-0.40.6-0.3-0.5-0.40.31.20.10.10.0
Locomotion in novel chamber0.60.82.30.6-0.31.20.2-1.50.5-0.90.90.8-0.00.81.0-1.10.9-0.7-1.00.70.70.90.90.8-0.80.60.80.91.5
Locomotion in novel chamber post-restriction0.91.43.0-0.60.40.90.7-1.21.2-1.21.01.21.31.31.7-1.50.9-1.1-1.01.31.21.31.11.2-1.31.31.31.51.3
Fecal boli incidents, locomotor time 10.40.61.8-0.20.4-1.30.01.3-0.30.6-0.5-0.5-0.6-0.5-1.01.0-1.10.31.0-0.6-0.7-0.20.4-0.60.6-1.3-1.1-0.8-0.9
Change in fecal boli incidents, locomotor task0.50.52.7-0.6-0.70.9-0.4-0.80.2-0.50.00.60.70.10.8-0.71.1-0.6-1.00.50.70.70.40.7-0.51.70.81.00.5
Time >=10cm from walls, locomotor time 10.60.62.51.4-1.61.3-1.3-1.1-0.6-0.1-0.50.2-0.6-0.40.2-0.11.0-0.2-1.0-0.30.80.40.3-0.20.21.2-0.10.50.2
Bouts of movement, locomotor time 11.11.23.11.4-0.4-0.1-0.90.0-1.31.1-1.1-1.2-1.2-1.2-1.30.8-1.21.20.8-1.3-1.2-1.4-1.8-1.41.3-0.4-1.0-1.0-0.8
Total resting periods, locomotor time 10.70.82.21.5-0.70.1-1.0-0.1-1.20.7-0.8-0.9-1.0-0.9-1.10.5-1.01.00.4-1.1-0.8-0.9-1.1-1.21.1-0.2-0.9-0.8-0.5
Rest time, locomotor task time 10.50.64.12.0-1.31.2-1.2-1.3-0.90.5-0.9-0.4-0.8-0.4-0.40.10.30.4-0.4-0.60.2-0.2-0.2-0.60.51.0-0.60.0-0.6
Distance moved, locomotor task time 10.71.02.1-1.50.50.10.90.01.1-1.41.11.21.01.01.0-1.31.1-1.1-0.61.10.81.31.01.2-1.10.31.20.91.1
Vertical activity count, locomotor time 10.30.61.3-1.00.6-0.10.80.10.9-0.80.90.91.10.80.8-0.70.7-0.9-0.40.90.70.70.20.9-0.90.21.10.90.8
Time >=10cm from walls, locomotor time 20.20.21.10.4-1.00.3-1.0-0.1-0.70.2-0.8-0.1-0.6-0.6-0.20.30.60.1-0.2-0.50.1-0.40.0-0.40.50.7-0.2-0.0-0.1
Bouts of movement, locomotor time 20.71.29.73.1-1.61.7-1.4-1.8-1.00.8-0.8-0.3-0.6-0.1-0.40.41.10.3-0.7-0.60.6-0.5-0.6-0.70.51.6-0.00.20.1
Total resting periods, locomotor time 21.01.712.13.5-2.01.8-1.8-2.0-1.51.3-1.2-0.8-1.0-0.6-0.80.80.90.7-0.5-1.00.3-0.9-1.1-1.10.91.6-0.4-0.1-0.2
Rest time, locomotor task time 22.53.212.03.5-2.41.1-2.6-1.2-2.51.9-2.0-1.8-2.0-1.9-1.71.5-0.31.70.3-2.0-0.7-1.6-1.5-2.11.90.7-1.6-1.2-1.1
Distance moved, locomotor task time 22.22.65.6-2.41.5-0.11.80.12.0-2.01.71.91.81.91.7-1.91.3-1.7-0.81.91.11.71.51.9-1.80.31.71.61.3
Vertical activity count, locomotor time 20.40.63.1-1.81.0-0.81.00.81.0-0.70.50.71.00.70.7-0.50.2-0.70.10.80.20.6-0.10.9-0.7-0.20.70.7-0.0
Light reinforcement 10.20.51.7-1.30.9-0.40.90.41.0-0.70.60.70.90.80.8-0.60.1-0.7-0.10.80.40.60.80.8-0.80.00.50.50.1
Light reinforcement 20.30.41.81.3-1.01.0-0.6-1.0-0.1-0.3-0.20.5-0.00.50.7-0.50.8-0.5-1.00.21.10.50.40.2-0.31.00.20.40.0
Bone: marrow area1.94.218.04.1-4.23.7-3.5-3.4-2.20.4-1.8-0.4-2.1-1.0-0.1-0.12.40.4-2.3-1.21.20.10.1-0.70.82.9-0.6-0.00.1
Bone: maximum diameter0.91.77.02.4-2.61.9-2.4-1.7-1.70.7-1.5-0.7-1.8-1.2-0.60.41.00.7-1.0-1.20.2-0.4-0.4-0.91.01.4-0.8-0.5-0.5
Bone: maximum force3.66.39.0-0.1-0.22.30.9-2.42.1-2.92.22.92.02.73.0-3.02.9-2.9-2.92.62.92.92.52.6-2.62.22.82.92.8
Bone: maximum moment3.05.37.90.2-0.42.30.7-2.41.8-2.61.92.61.62.42.7-2.72.7-2.6-2.82.32.72.62.32.3-2.42.12.52.72.6
Mean time between licks in bursts1.33.210.03.2-2.51.2-2.6-0.9-2.41.8-2.2-1.8-2.4-1.8-1.61.5-0.21.80.0-2.0-0.6-1.5-1.7-1.91.80.5-1.8-1.5-1.5
Mean num. licks in bursts1.01.54.8-0.82.1-1.12.21.01.6-1.01.91.21.51.50.9-0.8-0.0-1.30.31.30.30.70.80.9-1.2-1.41.01.20.8
Cd content in liver0.20.20.9-0.60.9-0.50.90.60.6-0.10.70.20.80.50.1-0.1-0.4-0.30.10.40.30.10.20.2-0.4-0.60.20.20.1
Co content in liver1.72.04.4-2.11.2-0.11.60.01.8-1.41.81.41.91.51.3-1.30.7-1.4-0.71.71.11.41.51.6-1.60.31.51.31.5
Cu content in liver1.31.55.9-1.82.2-2.31.62.30.70.40.5-0.50.4-0.1-0.60.7-1.70.51.70.0-1.3-0.6-0.6-0.20.2-2.4-0.4-0.9-0.7
Fe content in liver1.11.42.3-1.01.0-0.01.3-0.11.5-1.21.51.41.51.41.3-1.20.9-1.4-0.61.40.91.21.01.3-1.40.11.41.31.1
K content in liver0.20.21.1-1.10.8-0.80.60.70.4-0.00.20.10.20.0-0.10.3-0.3-0.10.50.2-0.5-0.1-0.30.2-0.1-0.60.3-0.10.2
Mg content in liver1.51.52.80.3-0.7-0.4-1.20.5-1.41.3-1.4-1.5-1.4-1.7-1.41.4-1.01.51.0-1.4-1.4-1.3-1.2-1.21.4-0.5-1.3-1.5-1.2
Mn content in liver4.85.48.52.3-2.00.1-2.60.1-2.92.5-2.9-2.7-2.9-2.9-2.42.4-1.32.71.3-2.7-2.0-2.3-2.4-2.52.6-0.3-2.5-2.6-2.3
Na content in liver1.11.14.3-2.11.2-0.51.30.21.5-1.21.31.01.51.11.0-0.90.3-0.9-0.21.30.41.00.91.3-1.20.11.30.71.1
Rb content in liver0.70.81.8-0.20.6-1.00.01.1-0.60.9-0.5-0.9-0.6-0.9-1.01.1-1.10.91.1-0.8-1.3-1.0-1.2-0.80.8-1.4-0.8-1.0-0.8
Se content in liver2.42.86.12.3-2.30.8-2.5-0.7-2.21.7-2.3-1.7-2.1-2.0-1.51.5-0.01.80.4-1.9-0.9-1.4-1.5-1.71.80.7-1.6-1.7-1.5
Sr content in liver0.30.31.00.7-1.01.0-0.7-1.0-0.2-0.2-0.00.2-0.00.10.4-0.40.7-0.2-0.70.00.60.40.20.1-0.11.00.20.30.4
Zn content in liver0.10.10.30.5-0.40.1-0.4-0.0-0.50.4-0.3-0.3-0.5-0.4-0.40.4-0.10.30.1-0.4-0.3-0.4-0.4-0.40.4-0.2-0.4-0.3-0.3
Bone: minimum diameter1.32.39.83.1-2.92.2-2.6-2.1-1.90.9-1.8-0.8-2.0-1.1-0.60.51.10.8-1.1-1.30.3-0.5-0.7-1.01.11.7-0.9-0.4-0.5
Time in familiar zone, hab. session 11.71.66.4-1.42.3-2.51.62.20.60.60.5-0.40.60.1-0.80.8-2.20.32.1-0.1-1.2-0.8-0.8-0.40.3-2.1-0.4-0.5-0.7
Time in novel zone, hab. session 11.01.04.21.5-2.02.1-1.5-1.7-0.7-0.2-0.70.1-0.8-0.30.4-0.41.6-0.0-1.6-0.20.90.40.40.00.11.60.00.20.3
Total zone transitions, hab. session 10.40.51.5-0.30.5-0.90.10.9-0.40.7-0.5-0.8-0.4-0.6-0.80.8-1.20.80.9-0.6-1.0-0.8-0.7-0.60.6-0.8-0.7-0.9-0.8
Total locomotion distance, hab. session 10.20.31.2-0.60.7-0.80.30.9-0.10.4-0.2-0.40.1-0.3-0.50.5-1.10.40.7-0.3-0.6-0.5-0.4-0.40.4-0.6-0.4-0.4-0.5
Locomotion velocity, hab. session 10.10.21.0-1.00.8-0.60.50.70.30.10.1-0.00.40.1-0.10.1-0.80.00.40.1-0.3-0.1-0.00.1-0.0-0.30.0-0.1-0.1
Time in familiar zone, hab. session 20.20.20.9-0.41.0-0.70.80.70.5-0.00.50.10.40.4-0.00.1-0.6-0.10.50.2-0.1-0.0-0.00.0-0.2-0.90.00.1-0.1
Time in novel zone, hab. session 20.10.10.40.1-0.40.5-0.2-0.50.0-0.30.00.30.00.10.3-0.30.6-0.3-0.50.20.30.30.40.3-0.20.60.30.30.4
Total zone transitions, hab. session 20.10.21.4-1.20.6-0.40.50.30.5-0.20.30.20.70.30.3-0.2-0.3-0.10.10.40.10.20.20.4-0.30.40.30.10.2
Total locomotion distance, hab. session 20.50.62.1-1.21.0-1.30.41.3-0.10.7-0.3-0.70.2-0.5-0.70.7-1.40.71.2-0.4-1.0-0.7-0.8-0.50.5-0.6-0.5-0.6-0.8
Locomotion velocity, hab. session 20.60.72.2-1.20.9-1.30.31.3-0.20.8-0.5-0.80.1-0.7-0.80.8-1.50.81.2-0.6-1.1-0.8-0.8-0.60.7-0.6-0.6-0.7-0.9
Novel to familiar place preference ratio0.20.21.2-1.10.5-0.30.50.30.5-0.50.40.30.40.30.4-0.40.1-0.3-0.00.4-0.00.40.40.5-0.4-0.20.40.10.3
Novelty place preference0.20.20.8-0.90.30.00.30.00.5-0.60.40.40.40.30.5-0.50.4-0.4-0.30.40.20.50.50.5-0.40.20.50.20.5
Time in novel zone, NPP test0.20.20.5-0.70.10.20.2-0.20.5-0.60.40.50.40.40.6-0.60.5-0.4-0.40.50.40.60.60.6-0.50.40.50.30.5
Total zone transitions, NPP test0.71.02.2-0.20.5-1.1-0.11.2-0.71.1-0.8-1.2-0.5-1.0-1.11.1-1.51.21.3-0.9-1.3-1.2-1.1-1.01.0-0.9-1.1-1.1-1.2
Total locomotion distance, NPP test0.50.72.2-1.11.2-1.50.61.50.00.6-0.1-0.60.2-0.4-0.70.7-1.40.61.3-0.3-1.0-0.7-0.6-0.50.5-1.0-0.5-0.6-0.7
Locomotion velocity, NPP test0.91.33.7-1.21.4-1.90.71.9-0.10.9-0.3-0.9-0.0-0.7-1.01.0-1.90.91.7-0.6-1.5-1.0-1.0-0.70.7-1.5-0.8-0.9-1.1
Intraocular pressure0.50.72.10.70.5-0.90.20.9-0.50.8-0.3-0.6-0.8-0.6-1.01.1-1.20.61.1-0.7-0.8-1.1-0.7-0.90.8-1.5-1.0-0.7-1.0
Delta distance traveled before/after self-admin1.61.73.3-0.7-0.10.70.4-0.91.1-1.61.01.71.11.41.5-1.51.5-1.6-1.11.31.31.81.71.4-1.31.41.31.71.1
Delta ambulatory time before/after self-admin0.91.12.7-0.1-0.50.8-0.0-1.00.7-1.00.61.40.61.01.0-1.01.5-1.4-0.90.91.21.41.01.0-0.91.41.11.60.9
Parametrial fat weight1.02.44.20.9-0.01.60.7-1.51.2-1.81.71.81.01.82.0-2.01.7-1.7-1.71.41.51.71.61.3-1.50.61.51.62.0
Pavlov. Cond. lever latency3.03.87.2-2.72.2-0.72.50.52.5-2.12.52.22.62.31.9-1.90.7-2.2-0.52.21.21.91.92.1-2.1-0.11.92.01.7
Pavlov. Cond. magazine entry latency3.34.36.82.5-1.80.2-2.30.0-2.62.4-2.6-2.3-2.5-2.4-2.22.1-1.12.31.0-2.4-1.6-2.1-2.2-2.42.3-0.3-2.2-2.0-2.1
Pavlov. Cond. change in total contacts0.80.93.71.9-1.81.4-1.6-1.3-1.10.6-1.1-0.6-1.2-0.7-0.30.30.70.6-0.7-0.70.1-0.3-0.3-0.60.61.0-0.4-0.4-0.2
Pavlov. Cond. index score4.25.39.03.0-2.30.5-2.8-0.3-2.92.6-2.9-2.6-2.9-2.7-2.42.3-1.02.60.9-2.7-1.6-2.3-2.4-2.62.6-0.1-2.4-2.2-2.2
Pavlov. Cond. latency score3.64.68.52.9-2.40.7-2.8-0.5-2.82.4-2.7-2.4-2.8-2.5-2.12.1-0.72.40.6-2.5-1.4-2.1-2.2-2.32.30.1-2.1-2.0-1.9
Pavlov. Cond. lever contacts2.83.36.62.6-2.20.9-2.5-0.7-2.42.0-2.4-2.0-2.4-2.1-1.81.7-0.42.00.3-2.1-1.0-1.7-1.8-1.92.00.4-1.7-1.7-1.5
Pavlov. Cond. magazine entry number3.64.56.5-2.11.40.32.1-0.52.5-2.52.52.52.42.52.4-2.31.5-2.4-1.42.51.92.32.42.5-2.40.72.32.12.3
Pavlov. Cond. intertrial magazine entries0.91.14.4-1.72.1-1.61.91.51.3-0.61.30.61.20.90.5-0.4-1.0-0.50.80.9-0.30.40.40.6-0.7-1.50.50.30.3
Pavlov. Cond. lever-magazine prob. diff.4.45.48.62.9-2.10.3-2.7-0.1-2.92.7-2.9-2.6-2.9-2.7-2.52.4-1.22.61.1-2.7-1.8-2.4-2.5-2.62.6-0.3-2.5-2.3-2.3
Pavlov. Cond. response bias4.45.48.32.8-1.90.1-2.50.1-2.92.7-2.9-2.6-2.8-2.7-2.52.4-1.32.61.2-2.7-1.8-2.5-2.5-2.72.6-0.4-2.5-2.3-2.3
Pavlov. Cond. lever latency0.20.20.90.4-0.70.8-0.4-0.8-0.0-0.40.00.4-0.10.10.4-0.41.0-0.3-0.80.20.60.40.60.3-0.20.60.20.20.3
Pavlov. Cond. magazine entry latency0.20.21.10.5-0.71.0-0.5-0.9-0.1-0.2-0.20.2-0.10.20.4-0.40.6-0.1-0.80.10.60.40.30.2-0.21.10.20.30.3
Pavlov. Cond. change in total contacts0.20.30.8-0.90.20.30.3-0.30.5-0.50.50.40.70.40.6-0.60.3-0.4-0.40.60.40.50.30.6-0.60.60.70.40.7
Pavlov. Cond. index score0.00.00.10.2-0.20.2-0.2-0.2-0.20.2-0.3-0.2-0.1-0.1-0.00.0-0.20.2-0.1-0.10.0-0.1-0.3-0.10.10.4-0.1-0.1-0.0
Pavlov. Cond. latency score0.00.00.2-0.1-0.00.20.0-0.30.1-0.10.00.10.20.20.3-0.30.0-0.0-0.20.20.20.20.00.2-0.20.50.20.20.2
Pavlov. Cond. lever contacts0.10.10.5-0.40.6-0.50.40.50.10.30.0-0.20.2-0.0-0.20.2-0.70.20.5-0.0-0.3-0.3-0.5-0.10.1-0.3-0.0-0.1-0.1
Pavlov. Cond. magazine entry number0.20.20.8-0.10.3-0.70.10.7-0.20.4-0.1-0.4-0.3-0.4-0.60.6-0.50.40.7-0.3-0.6-0.5-0.3-0.40.4-0.9-0.4-0.5-0.5
Pavlov. Cond. intertrial magazine entries1.82.74.11.8-1.1-0.4-1.50.6-1.91.8-1.8-2.0-2.0-1.9-1.81.8-1.11.91.1-1.9-1.4-1.7-1.5-1.91.8-1.1-2.0-1.9-1.8
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.2-0.10.2-0.2-0.2-0.20.2-0.3-0.2-0.1-0.1-0.10.1-0.30.2-0.0-0.2-0.0-0.1-0.3-0.20.20.3-0.1-0.1-0.1
Pavlov. Cond. response bias0.20.20.50.3-0.1-0.1-0.30.2-0.50.6-0.6-0.6-0.4-0.4-0.50.5-0.60.50.4-0.5-0.4-0.5-0.7-0.50.5-0.1-0.4-0.4-0.4
Time in closed arm before self-admin0.10.10.3-0.50.1-0.5-0.20.5-0.20.1-0.2-0.30.2-0.50.0-0.0-0.10.30.4-0.3-0.5-0.4-0.4-0.20.30.1-0.0-0.40.2
Time in closed arm after self-admin1.11.22.9-1.70.70.41.0-0.41.3-1.11.11.01.01.01.3-1.20.9-1.1-1.01.30.80.90.81.4-1.30.51.31.11.5
Time in open arm before self-admin0.50.61.30.8-0.5-0.1-0.70.2-0.81.0-0.6-0.9-0.7-0.6-1.21.1-0.70.80.5-0.9-0.5-0.9-0.3-0.90.9-0.3-1.0-0.7-0.7
Time in open arm after self-admin0.60.63.61.9-0.90.1-0.9-0.2-1.10.6-0.5-0.4-1.2-0.9-0.70.5-0.50.50.4-1.0-0.3-0.7-0.3-1.00.9-0.4-1.1-0.6-0.8
Bone: periosteal estimation1.32.810.42.7-3.03.2-2.1-3.1-0.8-0.6-0.60.6-0.90.20.9-1.02.5-0.6-2.50.01.81.00.80.3-0.32.70.50.80.9
Bone: periosteal perimeter0.71.35.62.2-2.42.0-1.9-1.9-1.20.2-1.0-0.2-1.2-0.6-0.0-0.11.30.2-1.3-0.60.60.1-0.1-0.40.41.6-0.3-0.00.0
Bone: post-yield work2.03.010.03.2-2.21.1-2.4-0.9-2.31.7-2.1-1.6-2.5-1.8-1.51.4-0.31.60.1-1.9-0.8-1.5-1.6-1.81.80.2-1.7-1.3-1.4
Progressive ratio test 1 active lever presses0.50.62.3-1.10.6-0.60.80.90.8-1.11.00.80.10.50.8-1.0-0.2-0.8-0.30.60.61.11.50.7-0.7-0.90.30.00.7
Progressive ratio test 1 breakpoint0.50.72.5-1.20.5-0.50.80.80.8-1.21.10.80.20.50.9-1.1-0.1-0.8-0.30.60.61.21.60.8-0.7-0.80.40.10.7
Progressive ratio test 1 inactive lever presses0.81.25.0-2.21.4-0.91.51.01.4-1.11.40.90.90.80.8-1.0-0.3-0.90.11.10.41.31.21.2-1.1-0.80.90.61.0
Progressive ratio test 2 active lever presses0.30.41.9-0.70.8-1.10.81.10.5-0.50.70.1-0.20.00.2-0.5-0.8-0.20.40.2-0.10.20.60.2-0.2-1.4-0.1-0.40.3
Progressive ratio test 2 breakpoint0.30.41.9-0.70.9-1.00.91.10.6-0.50.80.2-0.20.10.3-0.5-0.8-0.30.40.3-0.00.30.60.3-0.3-1.4-0.0-0.30.4
Progressive ratio test 2 inactive lever presses0.30.52.00.1-0.40.40.0-0.10.3-1.20.50.8-0.60.30.9-1.40.4-0.8-0.80.40.81.01.40.6-0.5-0.40.10.30.9
Incentive Sensitization - Responses0.30.41.3-0.20.4-1.10.10.9-0.30.5-0.3-0.7-0.4-0.6-0.70.5-1.10.71.1-0.5-0.8-0.6-0.5-0.60.5-0.8-0.8-0.7-0.5
Incentive Sensitization - Breakpoint0.40.51.3-0.10.5-1.20.21.0-0.20.6-0.2-0.7-0.4-0.5-0.70.5-1.10.61.1-0.5-0.8-0.6-0.5-0.60.5-1.0-0.7-0.6-0.5
Sum of active levers in priming session hrs 5-60.40.30.7-0.3-0.1-0.6-0.40.4-0.50.8-0.5-0.50.3-0.3-0.50.8-0.70.50.8-0.6-0.5-0.7-0.8-0.80.70.3-0.8-0.5-0.8
Progressive ratio4.57.013.5-0.1-0.22.31.1-2.42.2-3.12.53.02.03.13.2-3.42.9-2.9-2.82.63.13.13.72.7-2.72.22.42.92.8
Food seeking constrained by brief footshock0.00.00.2-0.10.3-0.20.20.00.0-0.00.30.00.20.0-0.3-0.1-0.30.00.3-0.1-0.4-0.1-0.1-0.10.1-0.30.00.00.2
Seeking ratio, punishment vs. effort3.95.611.1-0.40.3-2.1-0.92.1-1.82.9-2.1-2.6-1.6-2.7-3.03.1-2.62.52.7-2.3-3.0-2.7-3.3-2.32.4-1.9-2.0-2.5-2.3
Retroperitoneal fat weight0.41.83.40.7-0.01.50.6-1.31.1-1.51.31.50.91.61.8-1.71.4-1.5-1.71.31.61.51.51.2-1.30.91.21.41.5
Reaction time number correct0.81.64.4-2.11.7-0.61.80.41.7-1.11.61.31.71.30.8-0.90.3-1.4-0.11.50.61.00.61.3-1.3-0.11.51.31.3
Reaction time mean minus median2.05.130.65.5-3.02.0-2.9-1.7-2.92.2-2.5-2.0-3.1-1.7-1.62.00.02.0-0.2-2.3-0.2-1.6-1.6-2.52.10.5-2.0-1.7-1.6
Reaction time mean minus median AUC1.53.819.94.5-2.41.4-2.4-1.3-2.52.2-2.1-2.0-2.5-1.6-1.71.9-0.21.90.1-2.0-0.5-1.5-1.6-2.21.90.3-1.8-1.5-1.4
Reaction time num false alarms0.20.31.60.0-0.61.0-0.4-0.90.0-0.3-0.10.30.20.10.7-0.60.7-0.3-0.80.20.80.40.10.4-0.31.30.50.30.5
Reaction time num false alarms AUC0.30.52.2-0.2-0.81.0-0.5-1.00.1-0.6-0.00.50.20.20.8-0.80.9-0.4-1.00.40.90.60.40.6-0.41.50.60.40.7
Reaction time trials correct on left0.81.64.4-2.11.7-0.61.80.41.7-1.11.61.31.71.30.8-0.90.3-1.4-0.11.50.61.00.61.3-1.3-0.11.51.31.3
Reaction time trials on left0.81.43.8-1.91.5-0.61.70.31.6-1.01.51.21.61.30.8-0.80.4-1.4-0.11.40.61.00.61.3-1.3-0.11.51.31.3
Reaction time mean3.45.417.54.2-2.81.2-3.0-1.0-3.02.5-2.9-2.5-3.1-2.3-2.02.2-0.42.50.4-2.6-0.9-2.0-2.0-2.52.40.4-2.3-2.2-2.0
Reaction time mean AUC3.45.519.24.4-2.81.2-3.0-1.0-3.02.5-2.9-2.5-3.2-2.3-2.02.3-0.52.50.4-2.6-0.9-2.0-2.0-2.62.40.4-2.4-2.2-2.0
Median of all reaction times2.53.58.02.8-2.20.7-2.4-0.6-2.42.1-2.4-2.1-2.5-2.0-1.71.8-0.42.20.6-2.1-1.0-1.7-1.7-2.02.00.3-1.9-1.9-1.6
Reaction time omissions2.33.313.53.7-2.51.2-2.5-0.8-2.41.7-2.1-1.7-2.5-1.7-1.51.50.11.8-0.1-2.0-0.4-1.5-1.2-2.01.80.2-2.1-1.6-1.7
Reaction time false alarm rate0.40.62.70.9-1.61.2-1.5-1.1-0.90.1-1.0-0.3-0.8-0.60.2-0.20.60.5-0.8-0.60.5-0.0-0.1-0.30.41.4-0.3-0.4-0.2
Reaction time premature initiation rate1.31.82.9-0.8-0.11.10.4-1.11.2-1.51.11.51.21.31.5-1.41.7-1.4-1.51.31.51.61.51.5-1.41.41.51.31.5
Reaction time premature initiations2.03.65.6-2.00.80.71.4-0.82.1-2.12.02.22.12.02.0-1.91.9-2.2-1.62.11.82.21.92.2-2.11.32.42.02.2
Std. dev. reaction times2.85.125.55.1-3.32.1-3.2-1.8-3.02.2-2.6-2.0-3.1-1.9-1.61.90.22.0-0.4-2.3-0.1-1.5-1.5-2.32.11.0-2.0-1.7-1.6
Reaction time trials completed0.81.43.8-1.91.5-0.61.70.31.6-1.01.51.21.61.30.8-0.80.4-1.4-0.11.40.61.00.61.3-1.3-0.11.51.31.3
Reaction time trials AUC0.71.33.9-2.01.6-0.61.70.41.6-0.91.51.21.61.20.7-0.70.3-1.3-0.01.30.50.90.51.2-1.2-0.21.41.21.3
Run reversals in cocaine runway, females0.70.71.9-1.41.1-0.61.10.51.0-1.01.30.81.00.90.7-0.9-0.3-0.7-0.00.70.20.61.00.7-0.7-0.70.30.50.7
Run reversals in cocaine runway, males1.71.713.33.6-2.42.3-1.8-2.1-1.20.3-0.9-0.2-1.8-0.3-0.30.31.40.2-1.5-0.61.20.20.2-0.50.40.8-0.7-0.1-0.3
Latency to leave start box in cocaine runway0.20.20.6-0.7-0.1-0.5-0.30.6-0.30.4-0.7-0.3-0.4-0.8-0.40.50.10.20.4-0.3-0.6-0.7-0.2-0.20.4-0.3-0.20.1-0.3
Latency to leave start box in cocaine runway, F0.50.62.0-0.5-0.0-0.6-0.40.7-0.71.0-1.0-0.8-0.5-1.0-1.01.1-0.30.80.7-0.7-1.0-1.3-1.4-0.70.8-0.4-0.4-0.4-0.6
Latency to leave start box in cocaine runway, M0.60.62.9-0.3-0.20.40.2-0.40.6-0.90.40.90.20.50.9-1.01.0-0.9-0.70.70.70.81.70.8-0.80.30.61.10.8
Std. dev. time between licks in bursts1.82.47.12.1-2.61.3-2.7-1.2-2.21.5-2.2-1.5-1.9-1.8-1.31.20.21.5-0.2-1.7-0.4-1.1-1.2-1.41.61.2-1.4-1.1-1.1
Total sessions with >9 infusions0.60.82.8-0.30.20.40.7-0.50.9-1.31.10.90.00.81.1-1.50.3-0.9-0.70.80.91.11.70.9-0.9-0.30.50.50.8
Short access day 1 total inactive lever presses1.11.44.91.9-1.92.2-1.0-2.1-0.2-0.60.20.5-1.00.30.7-0.91.7-0.5-2.00.41.71.21.30.7-0.71.00.50.61.4
Short access day 10 total inactive lever presses0.20.51.20.2-0.2-0.9-0.30.8-0.50.7-0.7-0.7-1.1-0.6-1.00.9-0.60.61.0-0.6-0.6-0.4-0.4-0.50.5-1.1-0.7-0.5-0.9
Short access day 1 total infusions0.10.11.0-0.30.10.10.3-0.20.2-0.50.20.3-0.50.00.5-0.8-0.4-0.2-0.20.10.30.11.00.2-0.2-0.6-0.2-0.3-0.1
Short access day 10 total infusions0.60.72.7-0.30.50.30.9-0.20.9-1.21.20.8-0.20.81.0-1.40.1-0.8-0.70.80.71.11.60.9-0.9-0.80.60.41.1
Short access total infusions0.91.14.2-0.50.30.40.9-0.31.0-1.71.21.2-0.30.91.4-1.80.4-1.2-1.01.01.21.22.01.1-1.1-0.70.50.51.0
Short access day 1 locomotion0.91.13.0-0.40.4-1.2-0.01.1-0.60.8-0.5-1.1-1.3-1.2-0.90.7-1.71.11.5-1.0-1.3-0.9-0.4-0.90.9-1.7-1.3-1.4-1.0
Short access day 10 total locomotion0.20.42.30.5-1.31.1-1.1-1.4-0.60.2-0.4-0.4-0.3-0.40.3-0.10.30.4-0.4-0.30.2-0.1-0.2-0.10.21.50.3-0.20.5
Short access total locomotion0.10.10.6-0.2-0.60.2-0.5-0.3-0.3-0.0-0.0-0.3-0.7-0.50.1-0.2-0.30.30.0-0.3-0.00.00.3-0.10.2-0.1-0.2-0.70.2
One hour access (0.3 mA shock)0.91.14.3-0.30.5-1.80.12.1-0.50.3-0.2-0.8-0.7-0.9-0.70.3-1.60.71.4-0.9-1.1-0.90.0-0.90.9-2.0-1.3-1.2-1.0
Compulsive drug intake3.84.57.10.0-0.5-1.8-1.52.0-2.12.3-1.9-2.3-1.6-2.4-2.72.5-1.92.32.3-2.4-2.4-2.2-2.2-2.22.4-1.7-2.3-2.5-2.4
One hour access (shock baseline)0.60.92.50.50.50.10.9-0.00.9-1.41.21.20.41.21.4-1.50.5-1.2-0.80.91.11.11.60.7-1.0-0.30.50.90.9
Social response proportion0.20.20.90.5-1.00.7-0.9-0.7-0.50.2-0.6-0.3-0.5-0.5-0.20.00.30.3-0.3-0.40.20.10.0-0.20.31.0-0.2-0.2-0.2
Social responses0.20.21.2-0.4-0.50.6-0.3-0.70.1-0.4-0.00.40.20.10.4-0.50.5-0.3-0.50.20.50.60.40.4-0.31.10.50.50.5
Social time2.02.78.52.9-2.71.5-2.7-1.4-2.31.3-2.1-1.4-2.3-1.8-1.21.00.51.4-0.3-1.8-0.4-1.1-1.1-1.51.61.0-1.4-1.1-1.1
Soleus weight1.33.814.72.8-3.82.2-3.7-2.0-2.81.1-2.6-1.3-2.6-2.1-0.90.81.01.4-0.8-2.0-0.2-0.7-0.8-1.51.82.2-1.4-1.1-0.9
Bone: stiffness0.91.52.3-0.20.60.71.0-0.71.3-1.41.31.51.21.51.5-1.41.1-1.5-1.11.41.31.31.01.3-1.40.51.41.51.4
Tibialis anterior weight0.51.63.5-1.91.8-0.71.90.71.7-1.41.81.31.61.31.2-1.20.3-1.3-0.11.50.41.10.91.4-1.4-0.71.21.11.1
Time to tail flick, vehicle, before self-admin1.01.02.00.9-0.1-0.4-0.50.3-1.01.1-1.0-1.2-1.0-0.9-1.10.8-0.91.31.1-1.1-1.4-1.3-1.0-1.31.1-0.8-1.0-1.2-1.0
Time to tail flick, vehicle, after self-admin1.01.32.41.4-0.8-0.0-1.2-0.0-1.41.2-1.2-1.2-1.5-1.3-0.91.1-0.71.20.7-1.4-1.1-1.3-1.0-1.41.3-0.4-1.4-1.2-1.0
Time to tail flick, test, before self-admin0.00.10.40.60.2-0.00.10.1-0.1-0.00.1-0.0-0.00.1-0.0-0.1-0.20.00.1-0.1-0.3-0.1-0.5-0.20.1-0.5-0.20.0-0.3
Time to tail flick, test, after self-admin0.80.94.22.0-0.30.1-0.6-0.2-1.01.3-0.8-0.9-0.8-0.5-1.01.1-0.61.00.6-0.9-0.6-1.1-1.1-1.20.9-0.1-1.2-0.8-1.1
Delta time to tail flick, vehicle, before/after SA0.10.10.50.00.3-0.30.30.40.10.00.20.1-0.2-0.20.10.3-0.2-0.2-0.00.10.00.1-0.00.1-0.1-0.7-0.30.1-0.2
Delta time to tail flick, test, before/after SA0.20.20.7-0.40.7-0.80.40.70.10.7-0.0-0.50.1-0.2-0.50.7-0.60.50.8-0.1-0.5-0.6-0.3-0.30.2-0.3-0.3-0.4-0.1
Tibia length1.33.512.93.2-3.13.6-2.1-3.5-0.8-0.8-0.60.9-0.70.51.2-1.22.7-0.8-2.80.22.11.20.90.4-0.53.10.91.31.2
Ambulatory time before self-admin0.20.32.11.5-0.80.9-0.5-0.9-0.4-0.2-0.3-0.2-1.1-0.10.2-0.40.40.2-0.6-0.20.4-0.20.1-0.10.10.2-0.3-0.5-0.3
Ambulatory time after self-admin0.91.03.01.2-1.21.4-0.7-1.60.0-1.00.21.1-0.30.80.9-1.11.6-1.0-1.20.41.21.01.10.6-0.51.70.41.00.2
Bone: tissue strength3.63.65.4-0.2-0.21.80.7-1.81.6-2.21.82.21.51.92.1-2.22.2-2.2-2.31.92.22.22.12.0-2.01.62.02.12.1
Total heroin consumption0.10.10.90.9-0.70.2-0.6-0.2-0.50.1-0.30.1-0.6-0.2-0.20.00.2-0.0-0.0-0.40.10.00.1-0.40.30.2-0.5-0.1-0.2
Bone: trabecular number0.71.14.4-1.01.9-2.11.32.00.40.40.4-0.40.4-0.0-0.60.6-1.60.41.7-0.1-1.3-0.6-0.8-0.40.3-2.1-0.5-0.5-0.7
Bone: trabecular spacing1.92.66.70.9-1.92.6-0.9-2.50.3-1.40.51.30.30.91.5-1.52.4-1.3-2.50.92.11.61.71.2-1.12.41.31.41.6
Bone: trabecular thickness0.60.82.8-0.31.3-1.50.91.60.10.60.1-0.50.0-0.3-0.60.7-1.30.51.4-0.3-1.0-0.8-1.0-0.60.4-1.7-0.6-0.6-0.7
Bone: trabecular tissue density1.21.83.5-0.3-0.31.30.3-1.41.0-1.30.91.51.21.31.5-1.41.6-1.5-1.61.31.71.41.21.3-1.31.91.51.61.4
Water consumed over 24 hours0.00.00.20.0-0.30.2-0.4-0.3-0.30.0-0.3-0.0-0.2-0.3-0.00.00.20.0-0.0-0.2-0.2-0.0-0.2-0.10.20.30.00.2-0.0
Number of responses in last shaping day0.40.41.4-0.7-0.91.0-0.5-1.20.1-0.6-0.20.6-0.4-0.10.8-0.80.5-0.5-0.80.20.80.81.00.6-0.41.00.40.30.5