Hub : Genes

Cchcr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Cchcr1 0.45 0.13 1.6e-07 0.25 0.15 0.25 0.25 2.4e-07 7.3e-05 3.2e-07 2.7e-07
2 PL intron excision ratio chr20_3222005_3222255 0.03 0.02 3.8e-03 0.02 0.01 0 0.01 1.7e-03 1.7e-02 3.1e-01 2.9e-02
3 BLA isoform ratio XM_063279369.1 0.06 0.04 2.6e-03 0.03 0.03 0.04 0.03 8.4e-03 1.4e-02 3.6e-03 7.8e-03
4 Adipose mRNA stability Cchcr1 0.02 0.01 5.8e-03 0.02 0.02 0.02 0.02 1.9e-03 5.4e-03 1.2e-03 9.2e-04
5 IL gene expression Cchcr1 0.76 0.09 5.6e-17 0.46 0.47 0.47 0.48 1.7e-12 8.2e-13 1.1e-12 4.9e-13
6 Adipose gene expression Cchcr1 0.43 0.11 0.0e+00 0.46 0.47 0.47 0.47 3.6e-57 1.0e-58 1.3e-58 2.1e-58
7 BLA gene expression Cchcr1 0.86 0 0.0e+00 0.64 0.64 0.66 0.66 8.5e-44 7.1e-44 4.0e-46 8.3e-46
8 BLA alternative TSS NM_001002822.2 0.14 0.08 1.9e-04 0.07 0.06 0.04 0.06 1.6e-04 5.2e-04 2.2e-03 5.4e-04
9 BLA alternative TSS NM_001002822.2 0.13 0.07 2.7e-04 0.06 0.05 0.05 0.05 2.4e-04 9.0e-04 1.8e-03 1.2e-03
10 Brain gene expression Cchcr1 0.74 0.06 0.0e+00 0.6 0.62 0.65 0.65 3.2e-69 3.9e-73 3.7e-79 1.2e-78
11 NAcc gene expression Cchcr1 0.55 0.08 0.0e+00 0.58 0.6 0.61 0.61 7.4e-109 4.3e-114 3.6e-119 2.1e-119
12 OFC gene expression Cchcr1 0.88 0.05 0.0e+00 0.49 0.46 0.51 0.51 2.2e-13 1.9e-12 3.5e-14 6.1e-14
13 Brain mRNA stability Cchcr1 0.34 0.1 0.0e+00 0.37 0.35 0.35 0.35 1.4e-35 4.3e-34 9.7e-34 3.1e-34
14 IC gene expression Cchcr1 0.82 0.06 0.0e+00 0.4 0.43 0.46 0.45 3.5e-18 8.5e-20 2.0e-21 1.1e-20
15 BLA alternative TSS XM_039098946.2 0.08 0.05 3.8e-03 -0 0.01 -0 0 3.9e-01 1.3e-01 8.5e-01 2.9e-01
16 PL gene expression Cchcr1 0.66 0.05 0.0e+00 0.68 0.72 0.75 0.74 3.4e-102 4.5e-112 1.8e-122 1.4e-120
17 LHb gene expression Cchcr1 0.64 0.13 2.7e-11 0.44 0.39 0.42 0.44 7.6e-12 3.7e-10 3.5e-11 9.9e-12
18 PL alternative TSS NM_001002822.2 0.04 0.03 4.9e-03 0.03 0.03 0.02 0.02 8.7e-04 9.4e-04 2.7e-03 1.3e-03
19 PL alternative TSS NM_001002822.2 0.04 0.03 5.1e-03 0.03 0.02 0.02 0.02 9.4e-04 2.5e-03 4.4e-03 1.9e-03
20 pVTA gene expression Cchcr1 0.47 0.1 0.0e+00 0.35 0.41 0.42 0.43 2.3e-29 2.3e-35 2.7e-36 3.0e-37
21 LHb mRNA stability Cchcr1 0.17 0.09 7.2e-04 0.08 0.16 0.14 0.12 6.0e-03 1.5e-04 3.3e-04 7.1e-04
22 BLA intron excision ratio chr20_3222070_3222255 0.12 0.09 4.6e-03 0.01 0 -0 -0 1.4e-01 3.1e-01 5.2e-01 5.9e-01
23 IL alternative TSS XM_063279375.1 0.17 0.11 2.9e-03 0.01 0.04 -0.01 0.02 2.0e-01 4.1e-02 8.1e-01 9.3e-02
24 BLA alternative TSS XM_039098946.2 0.09 0.06 4.7e-04 0.03 0.03 -0 0.02 8.8e-03 1.4e-02 4.0e-01 2.3e-02
25 Liver gene expression Cchcr1 0.13 0.06 2.1e-09 0.09 0.07 0.07 0.08 9.2e-10 2.6e-08 1.5e-08 1.4e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.52.64.1-1.5-1.5-1.31.0-1.91.8-1.7-1.6-1.6-1.8-1.7-1.81.6-1.7-1.5-1.8-1.6-1.6-1.6-2.01.3-1.9-1.8-0.9-1.7
Area under the delay curve1.31.52.50.10.10.8-0.81.6-1.41.31.51.51.41.41.4-1.51.21.31.31.41.41.41.1-1.11.20.61.20.6
BMI with tail1.03.57.1-1.5-1.32.4-2.71.6-1.81.81.81.81.51.81.7-1.91.72.11.51.81.81.81.5-2.42.21.92.4-1.3
BMI without tail2.88.713.9-0.6-0.53.6-3.72.6-3.43.13.23.22.72.92.9-3.22.93.72.63.23.23.22.3-3.73.03.03.1-0.8
Body weight6.227.035.42.42.65.8-4.75.7-5.45.95.85.85.55.85.6-5.95.64.95.75.55.55.55.3-5.15.35.34.60.9
Weight adjusted by age2.84.37.71.41.62.2-1.52.1-2.22.12.32.32.12.22.1-1.92.12.02.32.32.32.32.2-2.12.02.81.31.0
Bone surface0.20.30.70.90.90.4-0.00.7-0.30.60.60.60.70.60.6-0.50.70.10.70.60.60.60.6-0.10.30.40.10.5
Bone volume0.00.10.3-0.2-0.10.4-0.30.2-0.10.30.40.40.20.30.2-0.30.30.10.20.40.40.4-0.0-0.2-0.00.10.4-0.5
Breakpoint value in progressive ratio session0.30.40.80.10.3-0.40.4-0.60.6-0.7-0.7-0.7-0.7-0.7-0.70.9-0.7-0.6-0.6-0.6-0.6-0.6-0.70.7-0.6-0.6-0.80.3
Number of licking bursts0.30.53.11.10.9-1.11.20.10.5-0.4-0.4-0.40.1-0.3-0.10.4-0.1-0.80.1-0.3-0.3-0.30.31.00.1-0.4-1.01.8
Context. condit. distance diff. score5.06.012.51.71.5-2.83.5-1.93.0-2.3-2.5-2.5-1.9-2.3-2.22.5-2.0-3.4-1.8-2.4-2.4-2.4-1.63.2-2.6-1.9-3.51.7
Locomotion velocity, session 10.30.30.70.50.8-0.60.9-0.20.4-0.4-0.5-0.5-0.3-0.4-0.30.4-0.4-0.6-0.4-0.5-0.5-0.5-0.30.7-0.4-0.5-0.80.7
Locomotion distance, session 10.60.81.7-1.3-1.3-0.90.5-0.90.9-0.9-0.8-0.8-1.0-0.8-0.90.7-1.0-0.7-0.9-0.8-0.8-0.8-1.10.7-0.6-1.3-0.1-1.0
Locomotion velocity, session 20.10.10.40.40.5-0.50.60.10.2-0.0-0.1-0.10.10.00.10.00.1-0.40.1-0.0-0.0-0.0-0.00.5-0.0-0.5-0.30.4
Locomotion distance, session 20.50.71.5-0.5-0.5-1.11.0-0.71.1-0.8-0.8-0.8-0.9-0.7-0.70.7-0.8-1.1-0.7-0.7-0.7-0.7-0.81.1-0.7-1.2-0.5-0.3
Locomotion velocity, session 30.10.20.9-0.9-0.80.4-0.6-0.1-0.3-0.00.00.0-0.1-0.0-0.1-0.1-0.10.6-0.20.00.00.0-0.3-0.50.0-0.00.6-0.9
Locomotion distance, session 31.61.72.7-0.6-0.6-1.41.3-1.51.5-1.3-1.3-1.3-1.4-1.4-1.41.3-1.4-1.4-1.4-1.2-1.2-1.2-1.61.4-1.5-1.6-1.0-0.8
Stereotopy head waving bouts, day 32.12.53.71.61.71.1-0.71.9-1.51.61.61.61.91.71.8-1.51.81.11.71.71.71.71.9-1.01.71.50.71.7
Stereotopy head waving duration, day 31.61.92.81.11.21.2-1.01.6-1.51.41.31.31.61.41.5-1.31.51.41.41.51.51.51.7-1.21.51.50.71.3
Locomotion velocity, session 74.95.48.5-0.3-0.5-2.72.6-2.42.9-2.3-2.4-2.4-2.4-2.4-2.42.4-2.2-2.9-2.2-2.3-2.3-2.3-2.32.7-2.6-2.6-2.2-0.8
Locomotion distance, session 74.55.79.3-1.0-1.1-2.92.6-2.52.8-2.4-2.4-2.4-2.5-2.4-2.52.4-2.3-2.7-2.5-2.4-2.4-2.4-2.62.7-2.5-3.1-1.9-1.1
Stereotopy head waving bouts, day 72.83.14.70.70.91.3-1.31.9-2.12.02.02.02.02.02.0-2.02.01.91.72.22.22.21.7-1.51.90.91.70.5
Stereotopy head waving duration, day 72.73.34.80.80.91.6-1.42.0-2.12.12.02.02.12.12.0-2.02.01.91.82.22.22.21.8-1.61.91.21.60.5
Locomotion velocity, session 81.31.58.62.92.8-0.91.80.90.30.40.20.20.80.40.6-0.20.7-1.00.80.20.20.21.11.20.20.1-1.52.9
Locomotion distance, session 83.24.610.81.21.1-2.73.2-1.62.8-1.9-2.0-2.0-1.7-1.9-1.82.0-1.8-3.3-1.5-2.0-2.0-2.0-1.53.1-2.3-2.1-2.81.2
Degree of sensitization distance0.30.31.40.90.7-0.81.0-0.10.6-0.3-0.4-0.4-0.1-0.3-0.20.5-0.1-0.8-0.2-0.5-0.5-0.50.10.8-0.2-0.2-0.91.2
Degree of sensitization stereotypy1.01.11.90.20.30.6-0.71.1-1.31.21.31.31.21.21.2-1.21.21.20.91.41.41.40.8-0.81.10.21.20.0
Conditioned locomotion0.80.91.50.90.90.8-0.61.1-0.81.01.11.11.11.11.1-0.91.10.51.21.01.01.01.2-0.60.91.10.50.9
Cocaine response after cond. corrected0.60.81.7-0.5-0.4-1.11.0-0.71.2-0.9-0.9-0.9-0.8-0.9-0.90.9-0.8-1.3-0.6-1.0-1.0-1.0-0.71.1-0.7-0.9-0.70.1
Cocaine response after cond. not corrected0.20.31.60.91.00.10.30.7-0.10.40.30.30.60.40.5-0.40.5-0.20.70.30.30.30.60.10.50.4-0.21.2
Cocaine response before conditioning5.97.19.02.32.22.8-2.03.0-3.02.92.82.83.02.83.0-2.92.82.72.82.82.82.82.8-2.42.52.81.61.7
Saline control response1.82.47.1-1.2-1.12.4-2.70.9-1.91.21.51.50.91.21.1-1.40.92.40.71.31.31.30.7-2.41.21.62.1-1.6
Bone: connectivity density2.33.65.2-0.7-0.7-1.71.6-2.22.3-2.1-2.0-2.0-2.1-2.1-2.12.1-2.1-2.1-2.0-2.0-2.0-2.0-2.01.8-2.3-1.6-1.8-1.0
Bone: cortical apparent density0.40.52.6-1.6-1.60.8-1.2-0.1-0.40.10.30.3-0.20.1-0.0-0.2-0.10.8-0.10.20.20.2-0.3-1.00.10.41.1-1.5
Bone: cortical area1.52.33.30.60.61.3-1.01.8-1.61.81.81.81.71.81.7-1.71.71.41.61.81.81.81.5-1.21.71.01.50.4
Bone: cortical porosity0.60.72.00.10.00.7-0.80.9-1.30.90.80.81.10.80.8-0.91.01.40.60.80.80.80.6-0.90.90.30.80.3
Bone: cortical porosity0.70.81.60.80.70.5-0.41.1-1.31.00.90.91.20.91.0-1.01.11.20.80.90.90.90.9-0.71.00.40.50.9
Bone: cortical thickness2.03.39.0-1.8-1.81.7-2.21.4-1.91.82.02.01.41.71.5-2.01.52.21.31.91.91.90.8-2.11.70.63.0-1.7
Bone: cortical thickness0.91.04.3-2.0-2.11.0-1.60.1-0.80.50.60.60.10.40.3-0.70.31.20.00.40.40.4-0.1-1.30.80.31.7-1.9
Bone: cortical tissue density0.30.42.2-1.5-1.50.7-1.1-0.2-0.30.00.20.2-0.20.1-0.1-0.2-0.10.7-0.10.10.10.1-0.3-0.90.00.41.0-1.4
Condit. Reinf. active minus inactive responses0.80.91.5-0.2-0.1-0.90.8-1.00.8-1.1-1.0-1.0-1.0-1.0-1.01.0-1.1-0.7-1.1-1.1-1.1-1.1-1.10.9-1.2-1.0-0.9-0.2
Condit. Reinf. active-inactive response ratio0.10.10.4-0.6-0.60.2-0.5-0.2-0.3-0.1-0.0-0.0-0.1-0.1-0.10.1-0.10.5-0.3-0.0-0.0-0.0-0.2-0.40.00.00.4-0.6
Condit. Reinf. active responses1.41.83.3-0.6-0.5-1.21.0-1.51.3-1.4-1.4-1.4-1.6-1.5-1.41.4-1.6-1.2-1.5-1.4-1.4-1.4-1.51.2-1.8-1.3-1.1-0.7
Condit. Reinf. inactive responses2.73.35.1-1.4-1.3-1.61.2-2.01.9-1.9-1.8-1.8-2.2-1.9-2.01.7-2.2-1.7-2.0-1.8-1.8-1.8-2.21.5-2.3-1.9-1.2-1.6
Incentive salience index mean1.51.83.80.80.9-1.71.9-1.11.5-1.3-1.3-1.3-1.2-1.2-1.11.3-1.3-1.8-1.1-1.3-1.3-1.3-1.01.8-1.6-1.4-1.70.7
Condit. Reinf. lever presses2.63.68.81.51.5-2.33.0-1.32.4-1.6-1.8-1.8-1.5-1.6-1.41.8-1.5-2.9-1.2-1.8-1.8-1.8-1.12.7-1.9-1.7-2.61.3
Condit. Reinf. active minus inactive responses1.11.52.20.70.81.1-1.01.5-1.51.31.21.21.41.31.3-1.41.31.41.31.01.01.01.4-1.31.11.40.90.8
Condit. Reinf. active-inactive response ratio2.63.04.71.31.41.2-1.12.2-1.91.91.71.72.21.92.0-1.92.01.62.11.71.71.72.1-1.41.71.81.11.5
Condit. Reinf. active responses0.00.10.20.20.30.1-0.10.0-0.2-0.1-0.1-0.1-0.1-0.1-0.10.0-0.20.3-0.1-0.4-0.4-0.40.0-0.2-0.40.4-0.20.2
Condit. Reinf. inactive responses1.52.03.5-0.7-0.6-0.60.6-1.71.3-1.6-1.5-1.5-1.8-1.6-1.71.6-1.9-1.0-1.7-1.7-1.7-1.7-1.60.8-1.7-0.7-1.2-0.9
Condit. Reinf. lever presses0.60.81.3-0.1-0.0-0.80.6-0.90.7-1.1-1.1-1.1-1.0-1.0-1.01.0-1.2-0.6-1.1-1.1-1.1-1.1-0.80.6-1.0-0.5-1.0-0.1
Condit. Reinf. lever reinforcers received0.10.10.30.30.4-0.10.0-0.1-0.1-0.3-0.3-0.3-0.2-0.3-0.20.2-0.40.1-0.2-0.5-0.5-0.5-0.1-0.0-0.50.3-0.40.3
Conditioned reinforcement - actives0.71.22.3-0.5-0.61.0-1.10.8-1.11.11.21.20.91.21.5-1.11.01.11.01.51.51.50.9-1.11.00.51.2-0.8
Conditioned reinforcement - inactives0.81.22.1-0.8-0.80.8-1.31.1-1.21.11.31.31.01.11.2-1.20.91.40.91.51.51.50.7-1.20.90.61.3-0.5
Conditioned locomotion0.20.30.60.30.3-0.1-0.00.6-0.50.50.60.60.60.70.8-0.50.50.40.60.60.60.60.6-0.40.20.50.4-0.0
Patch foraging indifference point 0 sec0.50.94.2-1.6-1.61.5-2.0-0.0-1.00.30.50.50.00.10.0-0.40.11.5-0.10.60.60.6-0.1-1.60.80.91.0-1.3
Patch foraging indifference point AUC1.01.52.80.50.40.7-0.71.7-1.41.51.31.31.51.51.4-1.61.51.31.31.31.31.31.2-1.01.00.61.40.6
Delay disc. indifference point, 0s delay0.50.51.70.80.80.3-0.21.1-0.50.70.70.70.90.80.8-0.70.70.21.00.70.70.70.9-0.10.50.30.21.3
Delay disc. indifference point, 16s delay1.21.33.2-1.3-1.60.8-1.41.2-1.30.91.31.30.91.01.0-1.30.71.50.81.11.11.10.5-1.31.00.21.8-0.7
Delay disc. indifference point, 2s delay1.92.13.70.70.91.1-1.01.7-1.61.51.41.41.81.51.5-1.51.51.41.71.61.61.61.6-1.11.91.10.91.8
Delay disc. indifference point, 24s delay0.40.41.2-0.5-0.60.6-0.80.7-0.90.40.60.60.60.60.5-0.60.61.10.30.30.30.30.4-0.90.90.50.90.5
Delay disc. indifference point, 4s delay2.83.04.61.41.21.6-1.22.1-1.91.91.91.92.01.92.0-2.01.81.71.91.91.91.91.8-1.51.31.51.10.9
Delay disc. indifference point, 8s delay0.20.20.4-0.3-0.10.00.00.6-0.50.40.60.60.50.50.5-0.50.50.40.40.60.60.60.3-0.30.4-0.10.40.1
Indifference point function ln k0.20.41.10.70.7-0.71.0-0.40.6-0.5-0.7-0.7-0.3-0.3-0.30.6-0.2-0.7-0.3-0.9-0.9-0.9-0.00.8-0.0-0.5-0.80.9
Indifference point function log k0.20.41.10.70.7-0.71.0-0.40.6-0.5-0.7-0.7-0.3-0.3-0.30.6-0.2-0.7-0.3-0.9-0.9-0.9-0.00.8-0.0-0.5-0.80.9
Patch foraging total patch changes 0 sec0.61.24.9-1.8-1.81.6-2.20.2-1.20.50.70.70.20.30.2-0.60.21.70.00.70.70.7-0.0-1.71.01.01.3-1.4
Patch foraging total patch changes 12 sec0.81.03.4-1.6-1.61.2-1.80.6-1.20.70.70.70.40.50.5-0.80.51.60.30.80.80.80.3-1.51.00.71.5-1.0
Patch foraging total patch changes 18 sec0.71.16.6-2.6-2.60.5-1.4-0.5-0.2-0.20.00.0-0.7-0.4-0.5-0.0-0.50.8-0.6-0.3-0.3-0.3-0.8-1.0-0.1-0.11.2-2.4
Patch foraging total patch changes 24 sec0.91.67.9-2.8-2.7-0.2-0.6-1.40.6-1.0-0.8-0.8-1.4-1.2-1.30.9-1.20.0-1.5-0.7-0.7-0.7-1.6-0.1-0.7-1.00.4-2.2
Patch foraging total patch changes 6 sec0.81.24.9-2.2-2.21.2-2.0-0.0-0.90.30.50.5-0.00.20.1-0.50.11.5-0.10.70.70.7-0.2-1.51.00.61.4-1.6
Patch foraging time to switch 0 sec0.30.62.0-1.4-1.4-0.1-0.3-1.10.8-0.7-0.5-0.5-1.1-0.8-0.80.9-0.9-0.5-0.7-0.5-0.5-0.5-0.80.0-0.6-0.1-0.1-1.3
Patch foraging water rate 0 sec0.40.72.1-0.2-0.20.7-0.61.0-1.00.90.80.81.01.01.0-1.01.00.90.90.70.70.71.0-0.91.40.71.10.4
Patch foraging water rate 12 sec0.10.21.2-1.0-1.1-0.30.0-0.50.2-0.3-0.2-0.2-0.5-0.3-0.30.1-0.40.0-0.4-0.1-0.1-0.1-0.7-0.0-0.6-0.60.3-1.1
Patch foraging water rate 18 sec0.20.30.50.50.50.6-0.30.6-0.60.60.70.70.50.70.7-0.60.50.50.50.70.70.70.5-0.60.10.70.3-0.1
Patch foraging water rate 24 sec1.21.72.8-0.1-0.11.1-0.91.5-1.41.51.51.51.41.61.5-1.61.51.31.41.31.31.31.1-1.21.30.71.7-0.3
Patch foraging water rate 6 sec0.10.11.0-1.0-1.0-0.1-0.0-0.1-0.1-0.0-0.0-0.0-0.10.00.0-0.1-0.10.3-0.1-0.2-0.2-0.2-0.2-0.30.3-0.20.7-0.5
Seeking ratio, delayed vs. immediate footshock0.50.61.40.50.51.2-1.00.9-1.00.70.80.80.80.80.9-0.70.61.00.51.01.01.00.5-0.80.30.70.30.4
Distance traveled before self-admin0.30.42.01.41.40.10.50.2-0.00.50.40.40.50.60.5-0.30.5-0.30.70.60.60.60.70.0-0.20.7-0.10.2
Distance traveled after self-admin1.41.83.01.41.41.4-1.01.1-1.41.31.31.31.51.41.2-1.31.31.11.31.71.71.71.3-1.21.11.60.80.5
Extensor digitorum longus weight0.10.31.61.31.20.40.10.5-0.10.30.30.30.40.30.4-0.30.4-0.20.60.30.30.30.60.00.20.7-0.31.0
Bone: elastic displacement0.20.31.0-0.9-0.90.4-0.80.0-0.50.30.30.30.10.20.2-0.40.10.70.00.40.40.4-0.1-0.60.5-0.10.8-1.0
Bone: elastic work1.72.23.3-0.2-0.11.3-1.51.5-1.71.71.81.81.41.61.6-1.71.51.61.41.81.81.81.3-1.51.80.91.8-0.3
Bone: endosteal estimation3.37.118.94.34.42.0-0.73.0-2.22.62.32.32.92.62.8-2.22.91.43.02.32.32.33.5-1.32.33.2-0.03.6
Bone: endosteal perimeter1.02.113.53.63.70.01.21.1-0.10.60.30.31.00.60.9-0.31.0-0.61.10.40.40.41.60.60.51.3-1.63.2
Epididymis fat weight2.17.444.1-6.6-6.42.5-4.3-0.5-1.30.40.90.9-0.50.3-0.1-1.0-0.22.7-0.40.70.70.7-0.9-3.21.30.63.9-5.5
Delta time in closed arm before/after self-admin0.50.51.2-0.1-0.10.8-0.80.8-0.60.50.60.60.70.60.6-0.60.60.60.60.70.70.70.8-0.71.10.80.60.5
Delta time in open arm before/after self-admin0.20.21.00.50.40.1-0.00.2-0.50.50.40.40.30.60.4-0.60.40.50.40.40.40.40.1-0.5-0.10.40.4-1.0
Diff in mean of infusions in LGA sessions4.45.47.2-1.4-1.2-2.61.9-2.32.7-2.6-2.7-2.7-2.5-2.6-2.52.6-2.4-2.6-2.3-2.3-2.3-2.3-2.42.5-2.4-2.5-1.90.1
Delay discount exponential model param1.41.52.6-0.1-0.1-0.90.8-1.61.5-1.3-1.5-1.5-1.4-1.4-1.41.5-1.3-1.4-1.3-1.4-1.4-1.4-1.11.1-1.3-0.7-1.2-0.6
Extinction: sum of active levers before priming0.50.61.3-0.20.1-0.80.6-0.80.8-0.9-0.9-0.9-0.6-1.0-0.70.9-0.6-0.9-0.6-0.6-0.6-0.6-0.40.9-0.4-0.6-1.01.2
Active lever presses in extinction session 60.30.31.3-1.2-1.0-0.1-0.3-0.50.2-0.5-0.4-0.4-0.6-0.5-0.60.6-0.70.1-0.7-0.3-0.3-0.3-0.8-0.1-0.2-0.30.1-0.8
Bone: final force4.57.210.5-0.3-0.32.9-2.82.7-2.82.93.13.12.62.92.8-2.92.72.82.63.03.03.02.4-2.83.22.23.2-0.5
Bone: final moment4.06.59.2-0.1-0.12.8-2.72.6-2.72.83.03.02.52.82.7-2.82.62.72.52.82.82.82.3-2.72.92.13.0-0.5
Food consumed during 24 hour testing period0.81.12.31.51.41.0-0.21.2-0.61.21.11.11.11.21.3-1.11.30.31.31.01.01.01.3-0.50.91.20.30.9
Glucose1.42.211.53.23.1-1.22.30.30.9-0.4-0.6-0.60.1-0.3-0.10.6-0.0-1.60.2-0.7-0.7-0.70.51.7-0.90.1-2.43.4
Heart weight2.33.67.20.00.22.1-2.12.0-2.31.81.71.72.11.91.9-1.92.02.31.81.71.71.72.0-2.12.72.11.91.2
Delay discount hyperbolic model param1.51.72.7-0.1-0.1-0.90.9-1.71.6-1.4-1.5-1.5-1.5-1.4-1.51.5-1.3-1.5-1.3-1.5-1.5-1.5-1.21.2-1.4-0.7-1.2-0.8
Intermittent access intake day 1-15 change0.00.00.20.2-0.3-0.10.2-0.10.1-0.0-0.2-0.2-0.2-0.1-0.20.0-0.3-0.1-0.2-0.1-0.1-0.1-0.30.1-0.4-0.20.0-0.5
Intermittent access intake escalation0.10.21.5-0.2-0.60.3-0.30.1-0.30.30.20.2-0.10.1-0.1-0.4-0.20.5-0.10.30.30.3-0.4-0.4-0.4-0.10.5-1.2
Intermittent access intake escalation 20.10.11.71.30.70.20.20.4-0.10.40.20.20.30.20.1-0.40.1-0.00.20.10.10.10.00.1-0.30.0-0.1-0.2
Intermitt. access day 1 inactive lever presses0.30.94.21.41.60.10.21.2-0.50.90.80.81.20.90.9-0.91.10.11.20.80.80.81.2-0.01.10.70.12.1
Intermitt. access day 15 inactive lever presses0.81.72.70.60.51.3-1.11.7-1.31.61.31.31.51.41.4-1.61.51.21.51.21.21.21.4-1.21.51.31.10.3
Intermitt. access escalation Index2.73.86.90.00.3-2.52.6-2.02.2-2.1-2.2-2.2-1.9-2.0-1.82.2-2.0-2.3-1.9-2.0-2.0-2.0-1.52.3-1.7-1.9-2.10.2
Intermittent access day 1 total infusions0.30.51.7-1.1-1.0-0.5-0.1-0.80.5-0.7-0.6-0.6-0.8-0.6-0.50.7-0.7-0.4-0.6-0.4-0.4-0.4-0.80.4-0.6-1.0-0.3-1.3
Intermittent access day 15 total infusions0.20.33.1-0.7-1.00.2-0.6-0.3-0.1-0.10.00.0-0.4-0.0-0.10.0-0.40.3-0.30.20.20.2-0.6-0.2-0.6-0.50.4-1.8
Intermittent access terminal intake (last 3 days)0.30.41.7-0.9-1.30.5-1.00.1-0.60.30.40.40.10.30.3-0.40.00.80.10.60.60.6-0.1-0.70.2-0.00.8-1.3
Intermittent access total infusions0.10.21.4-0.7-0.80.1-0.50.0-0.30.10.20.2-0.10.20.2-0.1-0.10.50.00.40.40.4-0.2-0.4-0.1-0.20.5-1.2
Intermittent access day 1 locomotion0.20.21.80.0-0.1-0.30.1-0.60.5-0.5-0.3-0.3-0.6-0.3-0.20.5-0.7-0.4-0.3-0.2-0.2-0.2-0.40.3-0.9-0.2-0.6-1.3
Intermittent access day 15 total locomotion0.91.62.81.00.80.8-0.71.3-1.21.51.61.61.31.51.7-1.51.11.11.51.61.61.61.3-1.10.61.20.9-0.8
Intermittent access total locomotion0.91.01.80.70.30.8-0.71.0-1.01.11.31.31.01.31.3-1.20.90.91.21.21.21.20.9-1.00.20.90.7-1.0
Intermittent access standard deviation1.43.05.2-0.6-1.12.0-2.31.7-1.91.61.81.81.51.61.6-1.81.32.11.52.12.12.11.2-2.21.41.72.1-1.0
Left kidney weight4.420.528.81.21.15.4-4.74.6-4.95.05.05.04.65.04.9-5.14.84.74.74.84.84.84.4-4.94.64.64.7-0.1
Right kidney weight4.721.630.31.71.75.5-4.74.8-4.85.25.35.34.65.25.1-5.24.94.55.05.15.15.14.5-4.74.44.74.50.1
Cocaine induced anxiety0.50.72.11.01.0-1.01.5-0.60.9-0.6-0.8-0.8-0.5-0.6-0.70.7-0.5-1.1-0.4-1.1-1.1-1.1-0.21.0-0.6-0.3-1.20.8
Post-drug Anxiety0.50.51.80.3-0.0-0.60.8-0.60.6-0.6-0.8-0.8-0.5-0.7-0.90.7-0.4-0.6-0.5-1.3-1.3-1.3-0.30.5-0.30.0-1.00.6
Baseline Anxiety0.60.63.5-1.7-1.9-0.2-0.4-0.60.4-0.9-0.8-0.8-0.8-0.9-0.90.8-0.70.0-0.8-0.9-0.9-0.9-0.60.00.0-0.2-0.0-0.2
Tail length4.818.623.84.54.54.2-2.74.8-4.54.94.64.64.94.74.6-4.74.83.74.84.54.54.54.6-3.43.84.42.33.0
Length with tail6.628.537.55.65.65.3-3.46.1-5.36.05.85.85.95.95.8-5.85.84.26.15.55.55.55.8-4.14.75.53.13.3
Length without tail5.618.125.53.53.54.4-3.14.9-3.94.84.64.64.64.84.7-4.64.63.15.04.54.54.54.9-3.44.34.63.12.3
Times rat made contact with spout1.72.04.6-2.0-2.0-0.80.1-1.80.9-1.4-1.3-1.3-1.7-1.5-1.61.3-1.6-0.4-1.9-1.3-1.3-1.3-1.80.5-0.9-1.6-0.2-2.1
Lifetime Intake0.20.31.0-0.5-0.50.4-0.80.2-0.60.40.50.50.20.50.4-0.40.20.70.40.70.70.70.1-0.60.20.10.6-1.0
Liver weight, left1.42.410.23.23.11.20.01.5-0.81.31.11.11.51.31.6-1.01.40.21.61.31.31.31.9-0.30.91.9-0.62.4
Liver weight, right3.25.513.03.63.41.8-0.72.8-1.92.52.32.32.62.42.6-2.22.61.12.82.52.52.52.8-1.02.02.20.22.7
Locomotor activity1.52.49.23.03.01.20.11.6-1.31.61.41.41.71.41.5-1.41.70.91.51.11.11.11.8-0.81.11.7-0.11.6
Locomotor testing distance0.30.52.61.61.60.40.40.6-0.50.60.50.50.80.50.6-0.50.70.20.70.20.20.21.0-0.30.51.0-0.31.2
Locomotor testing rearing0.40.92.81.61.70.9-0.20.9-0.70.90.80.81.00.90.9-0.91.00.51.10.40.40.41.3-0.60.81.40.20.8
Locomotion in novel chamber0.70.81.60.30.20.8-0.81.0-0.91.01.21.21.01.11.3-1.20.90.80.91.11.11.10.9-0.70.70.50.8-0.1
Locomotion in novel chamber post-restriction0.71.12.1-0.3-0.41.5-1.30.9-1.21.01.11.10.91.01.0-1.10.81.30.91.01.01.00.9-1.41.21.31.0-0.6
Fecal boli incidents, locomotor time 10.40.61.4-0.4-0.5-0.1-0.2-0.80.8-1.1-1.1-1.1-0.9-1.0-0.81.2-1.0-0.7-1.0-0.8-0.8-0.8-0.60.5-0.8-0.2-0.8-0.2
Change in fecal boli incidents, locomotor task1.11.03.50.60.60.4-0.11.2-0.91.11.11.11.41.10.9-1.41.30.61.30.70.70.71.2-0.51.90.70.61.5
Time >=10cm from walls, locomotor time 11.21.32.81.51.61.1-0.61.1-0.71.00.70.71.20.91.2-0.91.30.41.41.11.11.11.5-0.61.51.7-0.11.5
Bouts of movement, locomotor time 10.80.92.30.70.7-1.01.5-0.61.0-1.0-0.9-0.9-0.9-0.8-0.70.8-1.0-1.2-0.9-1.2-1.2-1.2-0.51.2-1.1-1.0-1.1-0.2
Total resting periods, locomotor time 10.40.41.10.90.9-0.61.1-0.30.7-0.6-0.5-0.5-0.5-0.5-0.30.4-0.7-0.9-0.5-0.7-0.7-0.7-0.10.9-0.8-0.6-0.9-0.1
Rest time, locomotor task time 10.30.42.41.41.60.5-0.10.7-0.40.60.50.50.60.60.4-0.50.50.20.40.40.40.40.7-0.10.40.6-0.40.8
Distance moved, locomotor task time 10.40.51.2-0.7-0.60.5-0.70.4-0.70.60.50.50.60.70.7-0.80.70.80.71.01.01.00.5-0.80.90.41.1-0.3
Vertical activity count, locomotor time 10.10.30.7-0.6-0.60.4-0.30.1-0.50.40.30.30.30.50.4-0.60.40.60.50.50.50.50.3-0.70.70.40.8-0.7
Time >=10cm from walls, locomotor time 20.30.42.71.01.00.6-0.10.3-0.30.30.00.00.50.30.5-0.20.70.10.60.10.10.10.9-0.31.01.3-0.31.6
Bouts of movement, locomotor time 20.50.74.02.01.90.60.20.9-0.70.90.90.90.90.91.0-0.61.00.40.60.50.50.50.8-0.20.50.5-0.10.5
Total resting periods, locomotor time 20.40.85.42.32.20.30.60.9-0.50.80.70.70.80.80.9-0.40.90.20.50.30.30.30.80.10.40.4-0.50.8
Rest time, locomotor task time 20.81.07.42.72.7-0.51.40.30.70.0-0.1-0.10.10.10.30.30.1-1.20.2-0.3-0.3-0.30.71.1-0.20.1-1.41.1
Distance moved, locomotor task time 20.80.92.8-1.7-1.51.0-1.30.3-0.80.70.50.50.50.60.4-0.90.71.10.70.90.90.90.2-1.31.00.61.7-0.8
Vertical activity count, locomotor time 20.10.21.4-1.2-1.10.3-0.3-0.1-0.20.0-0.2-0.2-0.0-0.1-0.4-0.2-0.10.50.10.10.10.1-0.3-0.60.50.50.6-0.3
Light reinforcement 10.00.10.9-0.9-0.90.3-0.5-0.00.00.10.40.4-0.10.0-0.2-0.0-0.10.10.10.10.10.1-0.1-0.30.20.10.4-0.3
Light reinforcement 20.50.71.51.01.10.8-0.41.1-0.51.01.11.10.91.00.8-0.90.80.31.20.90.90.91.0-0.50.60.90.30.4
Bone: marrow area3.27.118.54.34.32.1-0.83.0-2.22.62.32.32.92.52.8-2.22.81.43.02.32.32.33.5-1.42.33.30.03.5
Bone: maximum diameter0.91.76.82.62.60.10.71.4-0.61.10.90.91.41.11.3-0.81.4-0.11.41.01.01.01.60.21.00.7-0.52.3
Bone: maximum force3.66.59.10.20.22.7-2.42.7-2.62.83.03.02.62.82.8-2.82.62.52.62.92.92.92.4-2.52.92.12.8-0.1
Bone: maximum moment3.45.98.20.50.52.6-2.22.6-2.52.72.92.92.52.72.6-2.72.52.42.52.82.82.82.3-2.42.72.12.6-0.0
Mean time between licks in bursts0.41.16.82.62.6-0.71.50.50.40.1-0.0-0.00.40.10.2-0.00.3-1.00.50.00.00.00.51.1-0.6-0.1-1.52.1
Mean num. licks in bursts0.60.97.3-1.9-1.80.7-1.1-0.9-0.0-0.3-0.3-0.3-0.9-0.5-0.70.3-0.70.6-1.0-0.4-0.4-0.4-1.2-0.7-0.4-0.30.8-2.7
Cd content in liver0.20.31.2-0.9-0.8-0.0-0.2-0.70.6-0.5-0.3-0.3-0.7-0.5-0.60.5-0.6-0.5-0.5-0.2-0.2-0.2-0.60.1-0.5-0.20.2-1.1
Co content in liver0.70.92.4-1.4-1.41.1-1.60.3-0.80.60.80.80.40.50.5-0.60.51.10.40.80.80.80.5-1.31.00.91.5-0.9
Cu content in liver2.63.15.3-2.2-2.1-1.40.6-2.21.4-1.8-1.6-1.6-2.1-1.9-2.11.8-2.0-0.9-2.1-1.7-1.7-1.7-2.30.9-2.0-1.8-0.6-2.0
Fe content in liver0.50.61.5-1.0-0.81.1-1.20.5-0.80.70.80.80.40.70.5-0.70.61.00.40.60.60.60.3-1.10.70.61.2-1.1
K content in liver0.30.20.9-0.9-0.8-0.70.6-0.40.5-0.3-0.2-0.2-0.4-0.4-0.40.4-0.3-0.5-0.4-0.5-0.5-0.5-0.40.6-0.2-0.90.1-0.2
Mg content in liver0.91.02.60.60.6-1.41.6-0.51.1-0.8-0.8-0.8-0.6-0.8-0.70.9-0.6-1.4-0.5-1.0-1.0-1.0-0.41.5-0.7-1.0-1.21.4
Mn content in liver1.82.05.32.12.0-1.52.3-0.61.5-1.0-1.2-1.2-0.7-0.9-0.81.2-0.8-2.0-0.4-1.2-1.2-1.2-0.11.8-1.1-0.4-2.32.2
Na content in liver0.30.31.7-1.3-1.3-0.1-0.20.2-0.50.30.50.50.20.30.3-0.40.20.60.00.40.40.4-0.0-0.30.4-0.71.0-0.7
Rb content in liver1.01.11.8-0.5-0.4-1.00.9-1.01.3-1.2-1.2-1.2-1.1-1.1-1.11.0-1.2-1.2-1.0-1.3-1.3-1.3-0.91.0-1.1-0.8-0.8-0.1
Se content in liver0.91.06.22.22.5-1.01.70.30.3-0.0-0.2-0.20.3-0.10.10.40.3-0.80.1-0.2-0.2-0.20.51.2-0.2-0.4-1.52.2
Sr content in liver0.80.71.31.01.00.8-0.30.8-0.70.80.90.90.80.80.9-0.70.80.50.90.90.90.91.1-0.60.81.00.30.6
Zn content in liver0.00.10.30.40.6-0.10.3-0.00.2-0.0-0.1-0.1-0.0-0.1-0.00.10.1-0.30.0-0.1-0.1-0.10.20.30.00.1-0.30.5
Bone: minimum diameter1.22.18.62.92.90.50.51.6-0.71.31.01.01.51.31.4-1.01.40.11.61.11.11.11.9-0.11.11.4-0.52.5
Time in familiar zone, hab. session 14.24.16.5-2.2-2.2-1.50.7-2.41.6-2.1-2.0-2.0-2.5-2.2-2.32.0-2.6-1.1-2.5-2.1-2.1-2.1-2.51.0-2.0-2.0-0.7-2.5
Time in novel zone, hab. session 12.52.54.51.91.91.3-0.61.9-1.31.61.51.52.01.61.8-1.51.90.91.91.51.51.52.0-0.91.61.90.32.1
Total zone transitions, hab. session 10.70.91.5-0.4-0.6-1.10.9-1.01.0-1.1-1.0-1.0-1.2-1.1-1.01.0-1.2-1.0-1.1-0.9-0.9-0.9-1.01.0-1.1-1.0-0.8-0.1
Total locomotion distance, hab. session 10.50.71.2-0.6-0.8-1.10.8-0.91.0-1.0-0.9-0.9-1.0-0.9-0.90.9-1.1-0.9-0.9-0.8-0.8-0.8-0.90.9-0.7-1.0-0.5-0.2
Locomotion velocity, hab. session 10.30.40.9-0.8-1.0-0.70.4-0.60.6-0.7-0.6-0.6-0.7-0.6-0.60.6-0.8-0.5-0.7-0.4-0.4-0.4-0.60.5-0.3-0.8-0.1-0.2
Time in familiar zone, hab. session 20.40.41.7-0.8-0.9-0.1-0.2-0.90.4-0.6-0.5-0.5-0.9-0.7-0.70.6-0.8-0.1-0.9-0.5-0.5-0.5-0.90.1-0.6-0.5-0.1-1.3
Time in novel zone, hab. session 20.30.40.60.30.40.6-0.40.7-0.70.60.60.60.80.70.6-0.60.70.60.70.50.50.50.6-0.50.70.70.40.6
Total zone transitions, hab. session 20.10.10.4-0.6-0.6-0.60.2-0.20.3-0.2-0.2-0.2-0.3-0.2-0.20.1-0.4-0.3-0.1-0.1-0.1-0.1-0.20.3-0.1-0.50.2-0.2
Total locomotion distance, hab. session 21.21.62.7-1.0-1.1-1.61.3-1.31.6-1.4-1.3-1.3-1.4-1.3-1.31.3-1.5-1.5-1.2-1.2-1.2-1.2-1.21.4-1.0-1.5-0.8-0.4
Locomotion velocity, hab. session 21.31.83.5-0.9-1.0-1.91.5-1.31.7-1.4-1.4-1.4-1.4-1.3-1.31.3-1.5-1.7-1.2-1.3-1.3-1.3-1.21.6-1.0-1.7-0.9-0.2
Novel to familiar place preference ratio0.00.10.5-0.6-0.7-0.2-0.1-0.0-0.1-0.1-0.0-0.00.0-0.0-0.10.00.00.2-0.10.00.00.0-0.20.00.1-0.40.3-0.1
Novelty place preference0.10.10.2-0.4-0.40.0-0.30.2-0.40.20.20.20.30.20.2-0.30.30.40.20.30.30.30.1-0.20.3-0.20.50.1
Time in novel zone, NPP test0.20.20.3-0.2-0.30.2-0.40.4-0.60.40.40.40.50.40.4-0.40.50.60.40.50.50.50.3-0.30.5-0.00.50.2
Total zone transitions, NPP test1.21.72.8-0.4-0.5-1.71.5-1.31.6-1.4-1.4-1.4-1.4-1.3-1.41.3-1.4-1.6-1.2-1.3-1.3-1.3-1.31.5-1.4-1.5-1.2-0.2
Total locomotion distance, NPP test1.31.72.7-1.2-1.2-1.51.1-1.41.7-1.4-1.4-1.4-1.5-1.4-1.41.3-1.5-1.6-1.2-1.3-1.3-1.3-1.31.3-1.1-1.4-0.7-0.6
Locomotion velocity, NPP test2.23.04.6-1.4-1.4-1.91.5-1.82.1-1.9-1.8-1.8-1.9-1.8-1.81.7-1.9-2.1-1.7-1.8-1.8-1.8-1.81.8-1.6-1.9-1.1-0.7
Intraocular pressure0.81.22.3-0.4-0.5-0.70.5-1.31.3-1.1-1.1-1.1-1.3-1.2-1.21.1-1.2-1.1-1.2-1.0-1.0-1.0-1.30.8-1.5-0.8-1.0-1.1
Delta distance traveled before/after self-admin2.22.34.30.10.11.8-1.91.5-2.01.51.51.51.71.41.3-1.61.52.11.21.71.71.71.1-1.81.91.41.50.6
Delta ambulatory time before/after self-admin1.51.83.70.50.51.5-1.31.4-1.71.41.31.31.61.31.3-1.41.51.71.01.41.41.41.3-1.41.91.21.10.8
Parametrial fat weight1.02.34.70.30.22.2-1.91.2-1.21.71.71.71.31.71.8-1.61.61.21.61.91.91.91.3-1.70.91.71.5-1.2
Pavlov. Cond. lever latency1.11.45.7-2.2-2.21.7-2.40.0-1.00.30.40.40.10.30.1-0.50.11.60.00.50.50.50.0-1.90.91.21.7-1.9
Pavlov. Cond. magazine entry latency1.31.64.71.91.9-1.62.2-0.51.1-0.9-1.0-1.0-0.6-0.9-0.81.0-0.7-1.5-0.7-1.0-1.0-1.0-0.51.8-1.2-1.1-2.11.5
Pavlov. Cond. change in total contacts0.80.83.31.81.8-0.10.71.0-0.50.90.80.81.00.91.0-0.81.00.10.90.80.80.80.90.20.40.0-0.21.3
Pavlov. Cond. index score1.62.07.22.42.3-1.82.7-0.31.3-0.7-0.9-0.9-0.4-0.7-0.60.9-0.5-1.9-0.5-0.9-0.9-0.9-0.32.1-1.2-1.3-2.22.0
Pavlov. Cond. latency score1.31.76.42.42.4-1.72.5-0.01.0-0.4-0.5-0.5-0.1-0.4-0.20.6-0.2-1.7-0.2-0.6-0.6-0.6-0.02.0-0.9-1.2-1.92.1
Pavlov. Cond. lever contacts1.11.35.22.32.2-1.52.20.20.9-0.1-0.2-0.20.1-0.10.10.30.1-1.60.2-0.3-0.3-0.30.31.7-0.6-0.9-1.52.1
Pavlov. Cond. magazine entry number1.72.15.1-1.5-1.41.7-2.11.0-1.41.31.41.41.01.31.2-1.41.21.61.21.41.41.40.9-1.81.51.12.3-1.2
Pavlov. Cond. intertrial magazine entries1.01.24.4-2.1-2.10.1-0.6-1.10.6-1.0-0.8-0.8-1.2-0.9-1.10.7-1.2-0.1-1.0-0.8-0.8-0.8-1.3-0.2-1.0-0.40.3-2.0
Pavlov. Cond. lever-magazine prob. diff.1.72.27.42.22.2-1.92.7-0.51.4-0.9-1.0-1.0-0.6-0.9-0.71.0-0.7-1.9-0.6-1.1-1.1-1.1-0.52.2-1.4-1.4-2.31.8
Pavlov. Cond. response bias1.72.26.32.12.0-1.82.5-0.71.5-1.0-1.2-1.2-0.7-1.0-0.91.2-0.9-1.9-0.8-1.2-1.2-1.2-0.62.1-1.4-1.2-2.31.7
Pavlov. Cond. lever latency0.40.61.00.70.60.4-0.10.8-0.50.90.80.80.90.80.9-0.81.00.21.00.80.80.80.9-0.20.80.50.40.9
Pavlov. Cond. magazine entry latency0.30.40.70.70.70.0-0.10.8-0.50.70.80.80.70.70.8-0.70.70.30.70.80.80.80.7-0.20.40.20.30.4
Pavlov. Cond. change in total contacts0.10.20.6-0.3-0.30.2-0.50.4-0.70.30.30.30.40.40.3-0.40.40.80.20.20.20.20.3-0.60.30.20.6-0.2
Pavlov. Cond. index score0.00.00.10.20.2-0.2-0.00.1-0.1-0.00.00.0-0.0-0.00.00.0-0.10.1-0.10.00.00.00.0-0.0-0.2-0.0-0.1-0.0
Pavlov. Cond. latency score0.00.00.1-0.00.00.0-0.30.2-0.30.10.20.20.10.10.2-0.10.00.40.00.20.20.20.1-0.3-0.00.10.2-0.2
Pavlov. Cond. lever contacts0.20.30.6-0.6-0.5-0.3-0.1-0.60.2-0.6-0.5-0.5-0.6-0.6-0.60.5-0.7-0.0-0.7-0.6-0.6-0.6-0.60.1-0.6-0.3-0.2-0.8
Pavlov. Cond. magazine entry number0.20.20.5-0.3-0.2-0.10.2-0.60.4-0.5-0.7-0.7-0.5-0.6-0.60.5-0.5-0.3-0.5-0.7-0.7-0.7-0.60.3-0.4-0.2-0.40.0
Pavlov. Cond. intertrial magazine entries0.91.33.01.11.3-1.11.5-0.91.2-1.0-1.3-1.3-0.9-1.0-1.01.1-1.0-1.4-0.8-1.2-1.2-1.2-0.81.4-1.4-0.8-1.71.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.10.1-0.2-0.0-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.20.1-0.1-0.0-0.0-0.0-0.00.0-0.3-0.1-0.2-0.1
Pavlov. Cond. response bias0.10.20.40.10.2-0.60.4-0.30.4-0.5-0.4-0.4-0.4-0.4-0.40.5-0.5-0.3-0.5-0.4-0.4-0.4-0.40.4-0.6-0.5-0.5-0.2
Time in closed arm before self-admin0.10.10.40.0-0.2-0.00.1-0.10.1-0.2-0.3-0.3-0.1-0.10.20.40.1-0.1-0.0-0.5-0.5-0.50.20.1-0.10.1-0.20.6
Time in closed arm after self-admin0.60.71.4-0.9-1.00.8-0.91.0-0.80.80.80.80.70.80.9-0.80.80.90.60.70.70.70.7-0.81.20.41.10.1
Time in open arm before self-admin0.30.30.80.50.8-0.60.5-0.30.5-0.5-0.4-0.4-0.5-0.6-0.50.5-0.6-0.6-0.6-0.5-0.5-0.5-0.50.7-0.7-0.6-0.90.4
Time in open arm after self-admin0.20.21.11.01.1-0.60.6-0.50.2-0.3-0.4-0.4-0.3-0.4-0.30.3-0.4-0.2-0.3-0.4-0.4-0.4-0.40.3-0.60.0-0.8-0.2
Bone: periosteal estimation2.96.19.13.03.02.1-1.22.9-2.32.62.52.52.82.62.8-2.42.81.82.82.52.52.53.0-1.72.42.70.92.4
Bone: periosteal perimeter1.22.05.62.32.40.70.01.7-1.11.41.31.31.61.41.5-1.21.60.61.61.21.21.21.7-0.41.21.30.02.0
Bone: post-yield work0.60.85.82.42.4-0.11.10.40.40.0-0.1-0.10.20.10.20.10.1-0.90.4-0.2-0.2-0.20.70.6-0.20.8-1.41.8
Progressive ratio test 1 active lever presses0.10.10.7-0.8-0.80.0-0.5-0.1-0.2-0.10.00.0-0.20.00.20.1-0.10.3-0.00.10.10.10.1-0.30.2-0.00.4-0.4
Progressive ratio test 1 breakpoint0.10.10.6-0.8-0.80.1-0.6-0.0-0.2-0.10.10.1-0.10.10.30.1-0.00.30.00.20.20.20.1-0.30.30.00.5-0.3
Progressive ratio test 1 inactive lever presses0.20.43.4-1.7-1.80.0-0.8-0.20.0-0.1-0.0-0.0-0.3-0.0-0.1-0.1-0.20.3-0.1-0.0-0.0-0.0-0.3-0.40.0-0.20.7-1.0
Progressive ratio test 2 active lever presses0.40.41.2-1.0-0.8-0.60.1-0.70.5-0.7-0.6-0.6-0.8-0.6-0.40.7-0.8-0.3-0.7-0.4-0.4-0.4-0.90.4-0.8-1.0-0.0-1.1
Progressive ratio test 2 breakpoint0.40.41.5-1.1-0.9-0.60.1-0.70.5-0.6-0.5-0.5-0.8-0.6-0.40.6-0.7-0.3-0.7-0.3-0.3-0.3-0.90.4-0.8-1.00.1-1.2
Progressive ratio test 2 inactive lever presses0.30.51.30.20.30.3-0.40.8-0.50.70.70.70.60.71.0-0.60.60.40.81.11.11.10.7-0.30.80.20.30.3
Incentive Sensitization - Responses0.50.81.5-0.5-0.3-1.00.6-0.90.9-0.9-1.0-1.0-1.0-1.0-0.91.0-1.0-0.8-1.1-0.5-0.5-0.5-1.20.9-1.0-1.2-0.8-0.7
Incentive Sensitization - Breakpoint0.60.81.6-0.6-0.3-1.00.7-1.00.9-0.9-1.0-1.0-1.0-1.0-0.91.0-1.0-0.8-1.1-0.6-0.6-0.6-1.20.9-1.1-1.3-0.8-0.9
Sum of active levers in priming session hrs 5-60.30.31.00.00.3-0.30.1-0.60.5-0.7-0.7-0.7-0.5-0.7-0.40.8-0.6-0.4-0.7-0.5-0.5-0.5-0.30.5-0.4-0.2-1.00.4
Progressive ratio4.57.011.60.10.23.3-3.42.5-3.02.82.92.92.52.82.6-2.92.53.02.43.03.03.02.4-3.02.72.62.6-0.8
Food seeking constrained by brief footshock0.00.10.2-0.2-0.2-0.10.0-0.30.1-0.3-0.3-0.3-0.3-0.3-0.00.3-0.20.1-0.4-0.2-0.2-0.2-0.2-0.1-0.2-0.0-0.0-0.5
Seeking ratio, punishment vs. effort3.95.68.8-0.3-0.3-3.03.0-2.32.5-2.5-2.7-2.7-2.2-2.6-2.22.7-2.1-2.5-2.3-2.8-2.8-2.8-2.02.6-2.1-2.2-2.30.9
Retroperitoneal fat weight0.31.42.40.20.21.3-1.21.1-0.91.41.41.41.01.31.3-1.41.20.81.31.61.61.61.0-1.00.70.81.2-0.9
Reaction time number correct0.30.63.2-1.8-1.80.8-1.2-0.1-0.60.10.20.20.00.10.1-0.30.01.0-0.1-0.2-0.2-0.2-0.1-1.20.60.71.1-1.2
Reaction time mean minus median0.61.512.03.53.3-0.62.00.10.70.30.20.20.10.20.20.10.2-1.40.3-0.1-0.1-0.10.31.4-1.3-0.4-1.60.8
Reaction time mean minus median AUC0.51.27.32.72.6-0.92.0-0.10.90.0-0.1-0.1-0.2-0.1-0.10.30.0-1.5-0.0-0.4-0.4-0.4-0.01.5-1.3-0.7-1.50.6
Reaction time num false alarms0.30.41.10.50.5-0.10.31.0-0.60.70.60.60.80.80.7-0.80.80.40.70.50.50.50.7-0.10.7-0.00.40.9
Reaction time num false alarms AUC0.50.71.70.50.50.10.01.3-0.90.90.90.91.11.01.0-1.01.10.70.90.80.80.81.0-0.31.00.10.51.2
Reaction time trials correct on left0.30.63.2-1.8-1.80.8-1.2-0.1-0.60.10.20.20.00.10.1-0.30.01.0-0.1-0.2-0.2-0.2-0.1-1.20.60.71.1-1.2
Reaction time trials on left0.30.62.7-1.6-1.70.8-1.2-0.1-0.60.20.20.20.10.10.2-0.30.11.0-0.0-0.2-0.2-0.20.0-1.20.60.71.1-1.1
Reaction time mean1.11.79.23.03.0-1.22.2-0.01.2-0.2-0.3-0.3-0.1-0.2-0.30.50.0-1.90.2-0.7-0.7-0.70.11.8-1.5-0.4-2.01.5
Reaction time mean AUC1.11.79.63.13.0-1.12.1-0.01.2-0.2-0.3-0.3-0.2-0.2-0.30.5-0.0-1.90.2-0.7-0.7-0.70.11.8-1.5-0.4-2.01.3
Median of all reaction times0.81.15.12.32.2-1.11.70.01.1-0.2-0.4-0.4-0.1-0.2-0.30.50.0-1.60.2-0.7-0.7-0.70.11.4-1.2-0.3-1.61.3
Reaction time omissions0.71.17.22.72.7-0.71.40.10.80.1-0.2-0.20.20.1-0.10.10.4-1.30.4-0.4-0.4-0.40.31.3-0.9-0.2-1.51.2
Reaction time false alarm rate0.50.73.31.51.5-0.40.71.2-0.50.70.60.61.00.80.8-0.70.90.00.90.70.70.70.90.40.6-0.2-0.21.8
Reaction time premature initiation rate1.42.03.00.10.21.4-1.41.3-1.41.51.61.61.41.51.5-1.51.51.31.51.51.51.51.5-1.41.71.41.70.4
Reaction time premature initiations1.52.65.5-0.9-0.81.8-2.11.2-1.81.51.71.71.41.51.5-1.71.61.91.51.51.51.51.5-2.12.01.82.4-0.2
Std. dev. reaction times0.91.613.33.63.5-0.71.80.50.40.50.30.30.50.40.4-0.10.6-1.20.6-0.0-0.0-0.00.61.3-0.9-0.2-1.61.6
Reaction time trials completed0.30.62.7-1.6-1.70.8-1.2-0.1-0.60.20.20.20.10.10.2-0.30.11.0-0.0-0.2-0.2-0.20.0-1.20.60.71.1-1.1
Reaction time trials AUC0.30.52.9-1.7-1.70.7-1.1-0.1-0.50.10.10.1-0.00.00.1-0.30.10.9-0.1-0.3-0.3-0.3-0.1-1.10.50.61.0-1.1
Run reversals in cocaine runway, females0.20.21.3-1.1-0.90.1-0.7-0.4-0.0-0.3-0.0-0.0-0.4-0.2-0.20.2-0.50.3-0.20.30.30.3-0.3-0.4-0.20.00.3-1.1
Run reversals in cocaine runway, males1.51.56.42.52.50.60.31.3-0.71.41.31.31.31.41.2-1.11.40.11.31.31.31.31.2-0.10.60.6-0.20.7
Latency to leave start box in cocaine runway0.20.21.6-0.1-0.0-0.50.7-0.10.5-0.2-0.4-0.4-0.0-0.1-0.10.40.1-0.7-0.1-0.3-0.3-0.30.10.70.9-0.6-0.41.3
Latency to leave start box in cocaine runway, F0.50.51.6-0.10.1-0.91.3-0.70.9-0.5-0.9-0.9-0.5-0.6-0.40.8-0.2-1.0-0.5-0.8-0.8-0.8-0.21.00.2-0.8-0.71.0
Latency to leave start box in cocaine runway, M0.80.72.00.10.10.9-0.91.1-0.70.91.01.01.01.00.9-0.90.90.50.90.90.90.90.8-0.41.40.30.70.8
Std. dev. time between licks in bursts1.01.38.42.52.6-0.41.11.0-0.10.50.30.31.00.50.7-0.30.9-0.50.90.40.40.41.30.70.50.6-1.12.9
Total sessions with >9 infusions0.30.30.7-0.4-0.20.4-0.80.3-0.80.40.70.70.30.60.5-0.40.30.90.40.80.80.80.3-0.70.40.20.8-0.8
Short access day 1 total inactive lever presses2.12.84.61.71.51.0-0.72.0-1.51.91.91.92.02.02.1-1.92.01.12.01.71.71.71.9-0.91.51.20.91.4
Short access day 10 total inactive lever presses0.10.30.90.10.0-0.90.8-0.40.7-0.4-0.5-0.5-0.3-0.4-0.50.2-0.5-0.8-0.3-0.2-0.2-0.2-0.60.8-0.6-0.8-0.40.3
Short access day 1 total infusions0.00.00.1-0.3-0.3-0.2-0.3-0.3-0.0-0.2-0.1-0.1-0.3-0.1-0.10.3-0.30.1-0.10.10.10.1-0.1-0.00.1-0.10.1-0.3
Short access day 10 total infusions0.20.21.1-0.6-0.50.3-0.70.2-0.40.30.50.50.10.40.5-0.40.00.50.20.70.70.7-0.1-0.4-0.0-0.20.7-1.0
Short access total infusions0.30.40.7-0.6-0.50.4-0.80.3-0.70.50.70.70.40.60.6-0.50.30.80.50.80.80.80.3-0.70.50.10.8-0.6
Short access day 1 locomotion1.31.62.4-0.6-0.7-1.61.3-1.31.4-1.5-1.3-1.3-1.4-1.4-1.31.5-1.5-1.4-1.3-1.0-1.0-1.0-1.31.4-1.4-1.4-1.2-0.4
Short access day 10 total locomotion0.40.82.01.20.90.3-0.11.2-0.90.60.70.71.00.91.1-0.70.70.71.00.80.80.81.3-0.70.81.40.31.0
Short access total locomotion0.10.10.20.30.2-0.40.30.3-0.1-0.10.10.10.20.20.30.10.0-0.00.30.30.30.30.5-0.00.00.40.00.4
One hour access (0.3 mA shock)1.51.73.6-0.5-0.5-1.20.8-1.41.6-1.5-1.4-1.4-1.5-1.3-1.31.5-1.5-1.5-1.4-0.8-0.8-0.8-1.51.6-1.4-1.9-1.1-1.0
Compulsive drug intake3.13.77.10.50.5-2.52.6-1.92.4-2.1-2.2-2.2-1.7-1.9-1.72.2-1.7-2.7-1.6-1.8-1.8-1.8-1.22.6-1.5-1.8-2.31.0
One hour access (shock baseline)0.30.53.7-0.4-0.41.0-1.20.2-0.50.50.60.60.10.50.4-0.50.20.70.20.90.90.9-0.2-0.7-0.1-0.10.6-1.9
Social response proportion0.30.41.90.90.90.7-0.40.4-0.60.40.40.40.60.40.4-0.30.50.50.60.40.40.40.8-0.50.81.1-0.01.4
Social responses0.40.51.40.40.40.7-0.60.7-0.90.60.70.70.80.60.7-0.60.70.90.70.50.50.51.0-0.81.21.00.51.1
Social time0.91.37.72.82.7-0.61.60.90.20.50.30.30.80.70.7-0.30.9-0.90.90.40.40.41.11.00.4-0.0-1.12.0
Soleus weight1.13.317.63.73.80.21.01.9-0.61.20.90.91.81.31.6-1.01.7-0.41.91.01.01.02.50.41.51.5-0.94.2
Bone: stiffness0.60.91.9-0.5-0.51.2-1.10.9-0.91.01.11.10.81.00.9-1.10.81.00.81.01.01.00.6-1.11.00.81.4-0.7
Tibialis anterior weight0.20.53.1-1.8-1.80.6-1.1-0.1-0.40.10.20.2-0.10.10.0-0.3-0.00.7-0.20.20.20.2-0.3-0.80.3-0.01.2-1.4
Time to tail flick, vehicle, before self-admin1.01.02.20.40.2-0.81.2-1.11.4-0.9-1.0-1.0-1.1-0.9-0.91.1-0.8-1.5-0.9-1.0-1.0-1.0-0.81.4-1.4-1.3-0.9-0.5
Time to tail flick, vehicle, after self-admin0.50.61.71.10.8-0.91.2-0.60.9-0.6-0.8-0.8-0.6-0.6-0.41.0-0.5-1.1-0.4-0.7-0.7-0.7-0.11.1-0.6-0.6-1.30.5
Time to tail flick, test, before self-admin0.10.10.8-0.00.1-0.10.3-0.50.2-0.1-0.2-0.2-0.3-0.5-0.20.3-0.3-0.1-0.40.10.10.1-0.50.2-0.5-0.5-0.1-0.9
Time to tail flick, test, after self-admin0.70.82.40.70.5-0.50.9-0.80.9-0.5-0.5-0.5-0.8-0.7-1.00.5-0.7-0.9-0.8-0.9-0.9-0.9-1.21.0-1.6-1.2-1.1-1.1
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.4-0.5-0.50.2-0.30.2-0.3-0.2-0.2-0.3-0.3-0.40.4-0.4-0.1-0.3-0.3-0.3-0.3-0.30.10.1-0.4-0.4-0.3
Delta time to tail flick, test, before/after SA0.60.61.3-0.6-0.8-0.50.3-0.70.9-0.8-0.7-0.7-0.9-0.6-0.90.7-0.8-0.8-0.8-1.1-1.1-1.1-0.80.6-1.0-0.8-0.5-0.8
Tibia length2.87.711.73.23.32.7-1.53.2-2.62.92.72.73.13.03.1-2.83.01.93.22.62.62.63.4-2.02.93.41.22.6
Ambulatory time before self-admin0.10.20.70.80.80.00.40.1-0.10.40.40.40.30.50.3-0.40.3-0.00.60.60.60.60.4-0.0-0.30.30.2-0.3
Ambulatory time after self-admin1.72.03.11.31.31.5-1.11.2-1.51.51.41.41.61.51.4-1.41.51.41.41.81.81.81.5-1.31.51.51.00.5
Bone: tissue strength3.83.86.20.20.21.9-1.72.1-1.92.22.32.32.02.22.2-2.32.01.72.12.52.52.51.8-1.82.01.42.2-0.2
Total heroin consumption0.00.10.70.70.80.1-0.10.1-0.10.10.00.00.10.10.1-0.00.1-0.00.20.10.10.10.10.10.10.1-0.20.1
Bone: trabecular number1.72.94.6-1.8-1.7-1.51.0-1.91.8-1.7-1.5-1.5-1.9-1.7-1.81.6-1.8-1.5-1.8-1.5-1.5-1.5-2.11.4-1.9-2.1-0.7-2.0
Bone: trabecular spacing4.25.57.51.71.82.2-1.72.7-2.52.52.52.52.72.62.7-2.42.62.22.62.42.42.42.7-2.02.72.51.61.8
Bone: trabecular thickness1.62.03.1-1.2-1.2-1.00.8-1.61.6-1.4-1.4-1.4-1.6-1.4-1.61.3-1.5-1.3-1.4-1.4-1.4-1.4-1.81.1-1.7-1.4-0.8-1.6
Bone: trabecular tissue density1.21.83.00.30.31.1-1.01.5-1.71.51.51.51.61.51.5-1.51.51.61.31.41.41.41.3-1.31.70.71.40.3
Water consumed over 24 hours0.10.10.60.40.3-0.00.20.3-0.10.20.20.20.30.10.3-0.10.3-0.00.20.10.10.10.40.10.80.1-0.00.7
Number of responses in last shaping day0.80.93.10.50.20.4-0.51.2-1.10.80.80.81.10.91.0-0.81.01.01.00.80.80.81.3-0.71.80.90.51.7