Cchcr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Cchcr1 0.44 0.13 3.7e-08 0.27 0.2 0.28 0.28 5.7e-08 4.9e-06 3.8e-08 2.8e-08
2 PL intron excision ratio chr20_3217297_3217547 0.03 0.02 3.8e-03 0.01 0.01 0.02 0.01 3.5e-02 9.6e-03 5.4e-03 1.6e-02
3 pVTA gene expression Cchcr1 0.53 0.12 0.0e+00 0.26 0.34 0.38 0.33 2.0e-11 1.2e-15 9.9e-18 7.4e-15
4 BLA isoform ratio XM_039098942.1 0.09 0.06 1.5e-03 0.01 0.02 0.01 0 1.3e-01 3.2e-02 1.1e-01 1.7e-01
5 Brain gene expression Cchcr1 0.58 0.05 0.0e+00 0.61 0.66 0.68 0.68 1.6e-70 5.5e-81 1.2e-86 3.1e-86
6 Adipose gene expression Cchcr1 0.43 0.12 0.0e+00 0.42 0.45 0.44 0.45 1.1e-50 8.6e-55 5.5e-54 4.7e-55
7 IL gene expression Cchcr1 0.8 0.09 1.1e-16 0.41 0.47 0.42 0.46 5.5e-11 9.7e-13 3.4e-11 1.4e-12
8 Brain mRNA stability Cchcr1 0.34 0.1 0.0e+00 0.39 0.36 0.37 0.38 7.3e-38 4.6e-35 4.3e-36 4.0e-37
9 OFC gene expression Cchcr1 0.84 0.05 0.0e+00 0.46 0.41 0.44 0.45 3.0e-12 8.3e-11 1.3e-11 3.5e-12
10 Liver gene expression Cchcr1 0.14 0.07 6.0e-10 0.09 0.08 0.1 0.1 2.4e-10 4.0e-09 9.0e-11 7.7e-11
11 BLA gene expression Cchcr1 0.82 0.05 0.0e+00 0.58 0.63 0.65 0.65 6.6e-38 2.5e-42 1.2e-44 1.3e-44
12 LHb gene expression Cchcr1 0.61 0.12 4.0e-11 0.36 0.38 0.36 0.41 1.7e-09 6.3e-10 2.2e-09 7.6e-11
13 Adipose mRNA stability Cchcr1 0.02 0.01 5.3e-03 0.01 0.01 0.01 0.01 2.0e-02 7.9e-03 1.8e-02 2.4e-02
14 BLA alternative TSS NM_001002822.2 0.08 0.06 4.8e-03 0.04 0.02 0.01 0.02 4.9e-03 3.6e-02 6.0e-02 3.6e-02
15 NAcc gene expression Cchcr1 0.6 0.09 0.0e+00 0.62 0.61 0.64 0.64 9.9e-91 6.9e-90 4.6e-97 1.1e-97
16 PL gene expression Cchcr1 0.71 0.06 0.0e+00 0.69 0.72 0.75 0.75 9.9e-104 8.3e-115 2.7e-124 7.0e-124
17 LHb mRNA stability Cchcr1 0.14 0.08 2.9e-03 0.18 0.12 0.1 0.13 4.3e-05 9.6e-04 2.6e-03 5.1e-04
18 Brain isoform ratio XM_039098938.1 0.05 0.04 9.4e-03 0.03 0 0 0.02 1.7e-03 1.4e-01 1.0e-01 1.1e-02
19 BLA intron excision ratio chr20_3217362_3217547 0.12 0.08 4.0e-03 0 0.01 0.02 0 3.3e-01 1.2e-01 4.1e-02 2.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density2.03.36.0-2.12.12.3-2.51.91.9-2.0-1.71.7-1.61.8-1.91.41.7-1.71.8-1.40.81.6
Area under the delay curve1.41.42.60.4-0.3-1.01.0-1.6-1.51.11.6-1.60.6-1.41.6-0.7-1.51.5-1.21.3-0.3-1.1
BMI with tail1.34.26.91.0-0.5-2.31.6-2.6-2.41.92.6-2.5-0.4-2.52.2-2.6-2.52.6-2.62.20.50.2
BMI without tail3.26.510.52.2-1.5-3.03.1-3.0-3.22.42.9-2.90.5-3.02.7-3.0-2.92.9-2.81.8-0.5-1.5
Body weight5.623.633.84.6-3.7-5.74.9-5.7-5.45.25.7-5.80.3-5.85.4-4.6-5.75.7-5.84.2-0.4-0.6
Weight adjusted by age4.04.67.82.5-2.0-2.82.6-2.2-2.12.32.3-2.21.0-2.22.3-2.3-2.32.2-2.31.5-1.4-0.7
Bone surface0.20.31.30.7-0.6-0.60.5-0.5-0.40.70.5-0.50.7-0.50.60.1-0.50.5-0.6-0.6-1.1-0.2
Bone volume0.10.10.6-0.20.40.1-0.3-0.1-0.1-0.00.3-0.3-0.5-0.20.2-0.0-0.20.2-0.2-0.3-0.40.8
Breakpoint value in progressive ratio session0.80.91.5-0.70.50.9-0.81.11.2-0.8-1.11.20.81.2-1.01.01.2-1.11.0-1.1-0.5-0.5
Number of licking bursts0.50.62.40.6-0.7-0.20.20.20.40.4-0.50.51.30.3-0.11.10.5-0.40.2-1.5-1.4-0.9
Context. condit. distance diff. score3.54.210.10.1-0.51.5-1.42.32.8-1.0-2.42.41.72.3-2.03.22.5-2.52.0-3.1-0.4-0.6
Locomotion velocity, session 10.20.22.20.3-0.50.20.10.30.2-0.0-0.50.40.40.3-0.30.70.4-0.40.4-0.6-0.0-1.5
Locomotion distance, session 10.81.02.5-1.61.41.4-1.51.00.9-1.1-0.80.8-1.10.9-1.00.90.8-0.81.00.01.0-0.0
Locomotion velocity, session 20.10.10.90.3-0.50.10.1-0.1-0.00.3-0.0-0.00.6-0.10.10.8-0.00.0-0.0-0.10.1-0.9
Locomotion distance, session 20.50.72.1-1.00.71.2-1.30.81.0-0.6-0.80.7-0.30.8-0.71.40.7-0.70.7-0.50.7-0.4
Locomotion velocity, session 30.30.31.8-0.60.60.2-0.10.1-0.3-0.50.0-0.1-1.3-0.0-0.3-0.7-0.10.10.20.61.40.3
Locomotion distance, session 31.71.93.1-1.21.11.8-1.61.61.5-1.4-1.51.5-0.81.4-1.61.51.5-1.51.5-1.11.00.4
Stereotopy head waving bouts, day 32.22.64.12.0-1.8-2.02.0-1.8-1.62.01.6-1.61.0-1.71.8-0.7-1.61.6-1.60.3-1.5-1.1
Stereotopy head waving duration, day 31.72.13.91.7-1.5-1.92.0-1.5-1.61.51.4-1.40.7-1.41.5-1.3-1.41.4-1.30.2-1.5-1.0
Locomotion velocity, session 74.34.77.4-1.61.32.6-2.62.52.6-1.9-2.52.4-0.32.3-2.52.72.4-2.42.2-2.51.20.4
Locomotion distance, session 74.45.59.1-2.31.93.0-2.92.62.7-2.3-2.52.5-0.12.5-2.62.92.5-2.52.5-2.11.40.2
Stereotopy head waving bouts, day 71.71.93.51.1-1.0-1.21.5-1.6-1.91.21.7-1.7-0.3-1.71.6-0.9-1.61.6-1.31.7-0.5-1.1
Stereotopy head waving duration, day 72.32.94.71.5-1.4-1.61.8-2.0-2.21.62.0-2.0-0.2-2.01.9-1.2-2.02.0-1.71.8-0.6-1.1
Locomotion velocity, session 81.72.07.22.2-2.4-1.01.3-0.5-0.11.50.2-0.32.7-0.40.81.5-0.30.2-0.5-1.5-1.8-2.4
Locomotion distance, session 82.33.411.8-0.3-0.11.8-1.82.02.5-0.8-2.12.01.21.9-1.73.42.0-2.11.7-2.50.4-0.8
Degree of sensitization distance0.40.42.70.3-0.5-0.00.10.30.60.2-0.50.41.60.4-0.10.80.4-0.40.2-1.0-1.2-0.6
Degree of sensitization stereotypy1.01.12.50.6-0.6-0.60.9-1.2-1.40.81.3-1.3-0.3-1.31.2-0.4-1.31.2-0.91.6-0.2-1.1
Conditioned locomotion0.80.91.61.1-0.9-1.31.0-1.0-0.91.31.1-1.10.6-1.01.1-0.4-1.01.0-1.1-0.2-0.5-0.1
Cocaine response after cond. corrected0.60.61.5-1.00.60.9-1.20.81.1-0.5-0.80.80.60.8-0.71.20.8-0.80.6-0.5-0.20.3
Cocaine response after cond. not corrected0.50.62.90.9-1.0-0.80.6-0.6-0.20.90.4-0.41.7-0.50.60.3-0.40.4-0.7-0.0-1.1-0.7
Cocaine response before conditioning5.87.112.53.2-2.8-3.23.5-3.0-3.02.82.7-2.71.7-2.82.8-2.3-2.72.8-2.71.6-1.4-1.8
Saline control response1.21.66.3-0.30.6-0.70.6-0.9-1.3-0.01.1-1.1-2.2-0.90.4-2.5-1.01.1-0.81.91.71.8
Bone: connectivity density2.54.06.0-1.61.52.1-2.42.32.4-2.0-2.22.2-0.72.2-2.31.82.3-2.32.1-2.20.41.3
Bone: cortical apparent density0.70.93.2-1.11.20.1-0.4-0.3-0.6-0.40.5-0.5-1.7-0.30.1-1.4-0.50.5-0.31.31.41.8
Bone: cortical area1.62.54.11.1-0.8-1.61.4-2.0-1.91.72.0-2.00.5-2.02.0-1.0-2.02.0-1.90.8-0.8-0.4
Bone: cortical porosity0.40.41.30.00.1-0.40.8-0.7-1.10.20.8-0.8-0.1-0.70.7-1.0-0.80.7-0.41.00.1-0.7
Bone: cortical porosity0.90.92.01.0-0.8-1.01.4-1.0-1.30.81.0-1.00.7-1.01.1-0.6-1.00.9-0.70.4-0.8-1.4
Bone: cortical thickness1.62.75.2-0.91.3-0.70.3-1.8-2.10.62.2-2.2-1.6-1.91.6-1.8-2.12.1-1.62.31.40.6
Bone: cortical thickness0.81.03.4-1.31.60.2-0.6-0.3-0.6-0.50.7-0.7-1.8-0.40.1-1.3-0.60.6-0.31.31.81.1
Bone: cortical tissue density0.60.72.8-1.01.10.0-0.3-0.3-0.5-0.40.5-0.5-1.5-0.30.1-1.4-0.50.5-0.31.11.31.7
Condit. Reinf. active minus inactive responses0.70.71.8-0.40.50.8-0.61.10.8-1.0-1.11.00.11.0-0.90.71.0-1.11.0-1.30.2-0.2
Condit. Reinf. active-inactive response ratio0.10.10.3-0.40.50.00.00.1-0.2-0.4-0.10.0-0.10.1-0.1-0.60.0-0.00.1-0.10.3-0.2
Condit. Reinf. active responses1.21.52.2-0.91.01.4-1.21.51.3-1.4-1.41.4-0.31.4-1.31.01.4-1.41.3-1.50.80.4
Condit. Reinf. inactive responses2.73.25.3-1.91.82.3-2.21.91.9-2.0-1.71.8-1.21.8-1.91.41.8-1.81.8-1.11.81.4
Incentive salience index mean1.21.45.10.1-0.10.9-0.71.31.3-0.5-1.41.31.11.2-0.92.01.3-1.31.1-2.3-0.7-0.6
Condit. Reinf. lever presses1.92.58.30.2-0.41.3-1.11.62.1-0.5-1.71.81.51.6-1.22.91.7-1.81.3-2.7-1.1-0.4
Condit. Reinf. active minus inactive responses1.41.72.81.3-1.1-1.61.7-1.5-1.51.31.3-1.31.0-1.51.5-1.3-1.51.4-1.50.5-0.6-1.0
Condit. Reinf. active-inactive response ratio3.23.44.91.8-1.7-2.22.2-2.1-2.02.01.8-1.81.4-2.02.1-1.3-2.02.0-2.00.6-1.3-1.6
Condit. Reinf. active responses0.00.10.40.3-0.2-0.40.5-0.1-0.1-0.0-0.10.10.4-0.10.0-0.6-0.00.0-0.1-0.40.2-0.0
Condit. Reinf. inactive responses1.51.83.1-0.90.91.2-1.11.61.5-1.6-1.61.6-0.91.6-1.80.21.6-1.61.5-0.91.31.5
Condit. Reinf. lever presses0.30.40.9-0.40.50.6-0.30.70.6-0.8-0.80.80.50.7-0.80.00.7-0.80.6-0.90.5-0.2
Condit. Reinf. lever reinforcers received0.10.10.40.3-0.2-0.20.40.10.0-0.1-0.30.30.60.1-0.1-0.40.1-0.10.1-0.60.1-0.3
Conditioned reinforcement - actives0.30.30.70.2-0.1-0.60.5-0.6-0.60.50.6-0.70.9-0.60.7-0.6-0.60.6-0.70.4-0.3-0.8
Conditioned reinforcement - inactives0.60.71.70.10.4-0.60.6-1.0-1.20.41.3-1.1-0.3-1.00.9-1.2-1.11.0-0.91.10.5-0.2
Conditioned locomotion0.10.10.70.4-0.3-0.50.3-0.1-0.00.30.0-0.30.9-0.10.3-0.1-0.10.2-0.1-0.1-0.1-0.1
Patch foraging indifference point 0 sec0.61.04.8-0.81.2-0.20.1-0.3-0.6-0.50.5-0.4-2.0-0.40.1-2.2-0.60.6-0.21.41.41.5
Patch foraging indifference point AUC2.02.23.61.3-1.1-1.61.6-1.9-1.91.61.9-1.90.6-1.81.7-0.7-1.81.7-1.61.1-0.3-1.3
Delay disc. indifference point, 0s delay0.60.72.30.8-0.8-0.80.6-0.8-0.71.10.8-0.71.5-0.71.00.4-0.70.7-0.8-0.1-1.0-1.1
Delay disc. indifference point, 16s delay0.80.82.3-1.11.2-0.1-0.1-1.0-0.90.11.1-1.1-0.6-0.70.8-0.8-1.11.2-0.51.50.8-0.2
Delay disc. indifference point, 2s delay2.32.64.61.3-1.4-1.81.9-1.8-1.81.81.6-1.61.7-1.61.8-0.9-1.51.6-1.61.0-1.3-2.1
Delay disc. indifference point, 24s delay0.40.41.1-0.20.2-0.40.6-0.8-0.80.20.6-0.70.2-0.50.7-1.0-0.70.8-0.41.0-0.1-0.7
Delay disc. indifference point, 4s delay2.83.04.01.9-1.6-2.02.0-2.0-1.91.82.0-1.91.3-1.82.0-1.2-1.81.9-1.91.1-0.9-1.1
Delay disc. indifference point, 8s delay0.20.20.5-0.10.0-0.20.3-0.6-0.50.40.7-0.70.2-0.50.70.0-0.70.6-0.30.5-0.0-0.6
Indifference point function ln k0.30.41.40.2-0.40.4-0.00.60.7-0.1-0.90.90.70.6-0.40.80.7-0.80.5-1.2-0.9-0.3
Indifference point function log k0.30.41.40.2-0.40.4-0.00.60.7-0.1-0.90.90.70.6-0.40.80.7-0.80.5-1.2-0.9-0.3
Patch foraging total patch changes 0 sec0.81.25.4-0.91.3-0.30.2-0.5-0.8-0.50.7-0.7-2.1-0.50.3-2.3-0.80.7-0.41.51.61.5
Patch foraging total patch changes 12 sec0.70.83.0-0.81.1-0.30.2-0.7-0.9-0.20.9-0.8-1.2-0.60.4-1.7-0.80.8-0.51.51.30.5
Patch foraging total patch changes 18 sec1.62.08.9-1.92.20.9-1.20.3-0.1-1.30.10.0-3.00.2-0.7-1.3-0.10.00.41.42.92.0
Patch foraging total patch changes 24 sec2.12.67.4-2.72.71.8-2.01.20.8-2.1-0.70.8-2.41.1-1.4-0.40.7-0.81.30.72.21.6
Patch foraging total patch changes 6 sec0.81.24.1-1.21.7-0.0-0.2-0.4-0.7-0.70.6-0.6-2.0-0.40.0-2.0-0.60.5-0.31.51.61.4
Patch foraging time to switch 0 sec0.71.12.6-1.61.50.9-1.41.00.8-1.2-0.80.7-1.40.9-1.1-0.40.8-0.70.70.60.91.4
Patch foraging water rate 0 sec0.30.50.90.3-0.2-0.70.7-0.9-0.70.80.9-0.80.1-0.90.9-0.5-0.90.9-0.90.50.1-0.2
Patch foraging water rate 12 sec0.30.51.7-1.01.11.0-0.90.50.4-0.8-0.30.3-1.10.3-0.50.20.3-0.30.40.11.30.9
Patch foraging water rate 18 sec0.30.30.60.8-0.3-0.60.5-0.5-0.60.50.7-0.7-0.1-0.70.8-0.5-0.80.6-0.6-0.10.40.7
Patch foraging water rate 24 sec1.11.62.90.4-0.4-0.90.8-1.5-1.41.21.7-1.70.2-1.61.5-0.6-1.71.5-1.71.31.0-0.8
Patch foraging water rate 6 sec0.10.21.2-0.70.80.4-0.40.10.0-0.3-0.0-0.1-1.1-0.0-0.0-0.1-0.20.00.20.20.80.7
Seeking ratio, delayed vs. immediate footshock0.50.61.30.8-0.5-0.71.1-0.8-1.20.50.9-0.80.0-0.80.7-1.0-0.70.8-0.70.60.2-0.8
Distance traveled before self-admin0.20.20.80.9-0.7-0.50.1-0.00.30.50.10.10.5-0.10.10.40.0-0.1-0.3-0.9-0.30.7
Distance traveled after self-admin0.60.72.31.5-1.2-1.21.3-0.7-0.50.80.6-0.50.6-0.70.6-1.0-0.60.6-0.70.4-0.80.6
Extensor digitorum longus weight0.20.72.71.2-1.3-1.00.9-0.5-0.31.10.4-0.41.6-0.50.70.1-0.30.4-0.8-0.9-1.3-0.6
Bone: elastic displacement0.30.32.1-0.60.60.4-0.2-0.1-0.4-0.40.2-0.2-1.5-0.1-0.1-0.5-0.20.20.21.11.00.4
Bone: elastic work1.11.52.70.4-0.2-1.00.9-1.6-1.61.11.6-1.6-0.5-1.61.3-1.0-1.61.6-1.31.60.0-0.2
Bone: endosteal estimation4.59.722.24.7-4.4-4.04.2-2.9-2.53.72.4-2.43.5-2.73.1-1.5-2.42.4-3.0-0.2-3.7-2.2
Bone: endosteal perimeter1.83.812.73.3-3.3-2.12.3-1.0-0.52.20.5-0.53.6-0.91.40.5-0.50.5-1.2-1.6-3.3-1.8
Epididymis fat weight2.55.917.9-3.63.80.5-1.2-1.0-1.4-1.21.4-1.5-4.1-0.80.4-3.5-1.51.5-0.74.24.02.4
Delta time in closed arm before/after self-admin0.30.30.90.4-0.3-0.90.6-0.6-0.50.70.4-0.40.6-0.40.6-0.7-0.50.5-0.50.2-0.5-0.3
Delta time in open arm before/after self-admin0.10.10.6-0.00.30.2-0.10.0-0.1-0.40.00.0-0.6-0.1-0.3-0.30.00.0-0.00.20.70.6
Diff in mean of infusions in LGA sessions3.84.27.1-2.01.82.5-2.52.22.7-2.0-2.32.20.12.2-2.22.32.3-2.22.1-2.1-0.00.1
Delay discount exponential model param1.31.42.4-0.40.31.0-1.11.51.5-1.1-1.51.6-0.61.3-1.50.81.5-1.51.1-1.40.31.1
Extinction: sum of active levers before priming0.50.50.8-0.70.80.7-0.60.80.8-0.6-0.70.90.70.9-0.60.60.8-0.80.8-0.7-0.4-0.2
Active lever presses in extinction session 60.20.20.6-0.80.70.3-0.50.10.3-0.5-0.20.3-0.50.3-0.4-0.40.2-0.10.30.70.50.7
Bone: final force4.06.511.70.9-0.5-2.31.8-3.1-3.12.33.4-3.4-0.4-3.13.0-2.5-3.33.3-3.13.00.1-0.0
Bone: final moment3.76.110.81.0-0.6-2.31.8-3.0-3.02.23.3-3.3-0.4-3.02.9-2.4-3.23.1-3.02.80.10.1
Food consumed during 24 hour testing period0.91.12.61.6-1.5-1.21.1-1.1-0.81.51.1-1.10.4-1.11.1-0.1-1.01.0-1.20.20.0-0.6
Glucose2.43.617.52.5-2.8-0.91.20.10.71.5-0.60.64.20.30.32.10.6-0.6-0.3-2.5-3.7-2.3
Heart weight0.40.61.60.7-0.6-1.01.2-0.7-0.60.60.4-0.31.2-0.50.5-1.0-0.40.6-0.50.5-1.2-1.3
Delay discount hyperbolic model param1.61.62.6-0.70.61.2-1.31.61.6-1.2-1.61.6-0.81.4-1.60.81.5-1.61.2-1.30.41.3
Intermittent access intake day 1-15 change0.60.51.70.3-0.1-0.30.4-0.7-0.90.20.9-0.9-1.3-0.90.5-0.4-0.90.7-0.50.61.30.6
Intermittent access intake escalation0.30.30.70.8-0.7-0.30.4-0.5-0.50.40.6-0.6-0.8-0.70.40.1-0.60.4-0.40.10.70.6
Intermittent access intake escalation 20.60.63.51.9-1.8-0.30.6-0.30.00.90.2-0.20.5-0.40.31.3-0.20.1-0.2-1.0-0.7-0.1
Intermitt. access day 1 inactive lever presses0.70.72.51.2-1.2-1.11.0-0.7-0.31.20.5-0.41.4-0.50.9-0.0-0.40.4-0.80.0-1.6-0.4
Intermitt. access day 15 inactive lever presses2.12.33.61.0-0.8-1.71.6-1.8-1.91.51.9-1.80.1-1.81.7-1.6-1.81.7-1.81.5-0.5-0.2
Intermitt. access escalation Index2.62.33.7-1.10.71.7-1.51.91.9-1.3-1.91.9-0.01.9-1.61.71.9-1.81.9-1.3-0.10.0
Intermittent access day 1 total infusions0.60.71.1-1.10.91.0-1.00.90.8-0.9-0.80.80.30.9-0.80.70.9-0.90.9-0.60.3-0.3
Intermittent access day 15 total infusions0.20.20.6-0.70.60.6-0.60.50.3-0.6-0.20.2-0.50.3-0.40.40.3-0.40.5-0.30.80.4
Intermittent access terminal intake (last 3 days)0.00.00.1-0.20.3-0.10.1-0.1-0.2-0.10.2-0.20.1-0.10.2-0.2-0.20.1-0.10.10.3-0.1
Intermittent access total infusions0.10.10.3-0.50.60.3-0.30.30.1-0.4-0.20.10.00.2-0.2-0.10.1-0.10.3-0.10.60.2
Intermittent access day 1 locomotion0.20.20.50.2-0.20.0-0.10.60.5-0.3-0.50.40.40.5-0.40.10.5-0.50.4-0.70.20.4
Intermittent access day 15 total locomotion0.90.92.71.6-1.2-1.21.0-0.9-0.91.01.0-1.20.0-1.11.0-0.6-1.11.0-0.90.10.30.6
Intermittent access total locomotion0.50.51.71.3-1.0-0.90.6-0.7-0.60.70.8-0.8-0.0-0.80.6-0.4-0.80.8-0.70.00.80.7
Intermittent access standard deviation1.81.94.00.3-0.2-1.41.2-1.7-1.71.01.7-1.7-0.6-1.61.4-2.0-1.71.8-1.61.80.70.4
Left kidney weight3.39.214.02.5-2.1-3.32.9-3.6-3.43.03.6-3.6-0.2-3.73.4-3.0-3.63.7-3.63.30.2-0.4
Right kidney weight3.18.812.73.3-2.6-3.53.2-3.4-3.33.23.5-3.40.4-3.53.3-2.5-3.43.4-3.62.2-0.2-0.3
Cocaine induced anxiety1.61.94.40.2-0.41.0-1.01.61.9-0.8-1.61.70.21.4-1.51.91.7-1.71.3-2.1-0.31.2
Post-drug Anxiety0.50.61.20.3-0.50.1-0.20.81.0-0.1-1.11.00.70.8-0.70.71.0-0.90.6-1.1-1.00.7
Baseline Anxiety0.20.21.2-0.60.6-0.30.4-0.3-0.4-0.0-0.0-0.10.7-0.00.3-1.1-0.10.2-0.20.7-0.6-0.5
Tail length5.617.131.05.6-4.9-5.05.3-4.5-4.34.84.1-4.22.5-4.44.4-2.3-4.24.1-4.31.3-2.6-3.0
Length with tail4.616.925.85.1-4.5-4.94.7-4.6-4.34.84.5-4.61.4-4.74.6-2.5-4.54.4-4.62.7-1.4-1.6
Length without tail3.06.610.12.7-2.5-3.02.3-3.0-2.53.13.1-3.10.8-3.03.1-1.4-3.03.0-3.22.3-0.5-0.2
Times rat made contact with spout2.42.76.0-2.02.12.0-1.81.61.1-2.2-1.31.3-2.51.5-1.70.21.4-1.41.8-0.21.91.5
Lifetime Intake0.00.00.2-0.30.40.1-0.10.20.0-0.2-0.10.00.50.1-0.1-0.10.1-0.10.1-0.20.2-0.1
Liver weight, left0.81.34.12.0-1.9-1.71.5-1.0-0.91.41.0-1.00.7-1.11.0-0.7-0.80.9-1.20.3-0.60.2
Liver weight, right4.47.313.73.7-3.6-3.03.2-2.8-2.63.32.5-2.52.1-2.82.9-0.5-2.52.5-2.71.2-2.2-2.6
Locomotor activity2.03.211.03.3-2.8-2.22.5-1.6-1.71.91.3-1.41.4-1.71.6-0.9-1.51.4-1.50.2-0.9-1.6
Locomotor testing distance0.40.62.41.6-1.3-1.11.2-0.6-0.70.80.4-0.40.9-0.60.5-0.7-0.40.4-0.60.1-0.5-0.9
Locomotor testing rearing0.71.23.92.0-1.7-1.61.4-1.0-1.01.30.7-0.80.6-1.00.9-0.8-0.90.8-1.10.4-0.4-0.6
Locomotion in novel chamber0.50.61.20.7-0.5-0.80.7-0.9-0.90.81.1-1.0-0.3-1.01.0-0.5-1.11.1-0.80.7-0.20.1
Locomotion in novel chamber post-restriction0.50.61.50.2-0.1-0.80.6-0.9-0.80.60.8-0.8-0.3-0.80.7-1.2-0.81.0-0.81.20.20.3
Fecal boli incidents, locomotor time 10.60.61.2-0.40.40.6-0.61.10.8-0.9-1.01.1-0.01.0-1.10.11.1-1.10.8-0.50.40.6
Change in fecal boli incidents, locomotor task1.31.24.20.7-0.8-1.01.0-1.2-0.61.30.7-0.91.7-0.81.30.0-0.81.1-0.90.4-2.1-1.7
Time >=10cm from walls, locomotor time 11.21.23.41.8-1.8-1.71.3-1.0-0.71.50.6-0.71.0-1.01.0-0.5-0.50.7-1.10.3-1.5-0.1
Bouts of movement, locomotor time 10.80.92.30.1-0.00.8-0.71.11.2-0.6-1.01.20.31.1-1.11.41.1-1.11.1-1.5-0.10.6
Total resting periods, locomotor time 10.40.51.60.4-0.40.4-0.40.60.8-0.2-0.60.80.50.7-0.71.20.7-0.70.6-1.30.00.4
Rest time, locomotor task time 10.30.42.81.7-1.3-0.80.9-0.2-0.20.60.10.10.0-0.30.10.0-0.00.1-0.2-0.5-0.40.5
Distance moved, locomotor task time 10.30.41.1-0.40.3-0.30.2-0.7-0.80.30.7-0.8-0.1-0.70.7-0.7-0.70.8-0.71.00.1-0.4
Vertical activity count, locomotor time 10.20.21.0-0.50.3-0.2-0.0-0.4-0.60.10.3-0.4-0.5-0.40.2-0.7-0.40.5-0.31.00.60.3
Time >=10cm from walls, locomotor time 20.60.63.71.1-1.1-1.21.0-0.3-0.30.90.0-0.11.1-0.30.5-0.60.00.1-0.30.1-1.9-0.2
Bouts of movement, locomotor time 20.91.03.92.0-1.7-1.11.4-0.8-1.01.01.0-0.90.4-1.00.9-0.2-0.80.7-0.70.1-0.4-0.8
Total resting periods, locomotor time 21.01.14.82.2-2.0-1.11.5-0.7-0.81.10.8-0.70.8-0.80.80.1-0.70.5-0.5-0.3-0.9-0.9
Rest time, locomotor task time 20.91.04.92.2-2.1-0.80.7-0.00.21.1-0.20.31.1-0.10.11.30.2-0.2-0.3-1.4-1.30.6
Distance moved, locomotor task time 20.40.51.8-1.11.1-0.0-0.3-0.5-0.7-0.10.4-0.6-0.6-0.50.3-1.1-0.50.6-0.51.40.7-0.1
Vertical activity count, locomotor time 20.20.20.8-0.90.80.2-0.30.0-0.0-0.4-0.20.0-0.20.0-0.2-0.90.20.1-0.00.80.70.2
Light reinforcement 10.20.31.2-0.80.80.3-0.5-0.20.1-0.10.3-0.3-1.0-0.20.1-0.4-0.30.5-0.11.10.40.9
Light reinforcement 20.60.81.31.1-1.0-0.90.6-1.1-0.71.11.2-1.1-0.5-1.01.1-0.3-1.11.1-0.90.6-0.50.8
Bone: marrow area4.59.722.04.7-4.4-4.04.2-2.9-2.53.72.4-2.43.5-2.73.1-1.6-2.42.4-3.0-0.2-3.6-2.2
Bone: maximum diameter1.52.87.12.4-2.4-1.71.7-1.3-0.92.11.1-1.12.5-1.31.70.6-1.11.1-1.4-1.0-2.7-1.5
Bone: maximum force3.56.010.41.2-0.8-2.31.9-3.0-3.02.33.2-3.2-0.4-3.12.9-2.2-3.13.1-3.02.60.0-0.2
Bone: maximum moment3.35.79.81.4-0.9-2.32.0-2.9-3.02.33.1-3.1-0.3-3.02.8-2.1-3.03.0-2.92.40.1-0.2
Mean time between licks in bursts1.11.55.42.0-2.1-0.71.1-0.20.11.2-0.10.12.2-0.20.51.30.1-0.1-0.3-1.5-2.3-1.4
Mean num. licks in bursts1.31.56.6-1.51.71.1-1.00.60.2-1.4-0.20.2-2.60.4-0.8-1.00.2-0.30.71.42.41.7
Cd content in liver0.50.52.4-0.60.8-0.0-0.6-0.4-0.4-0.00.7-0.7-1.5-0.50.2-0.5-0.60.6-0.40.71.41.0
Co content in liver0.91.13.8-0.50.6-0.90.5-1.0-1.20.41.2-1.2-1.0-0.90.9-2.0-1.21.2-1.01.60.5-0.2
Cu content in liver4.25.18.7-2.92.72.9-2.82.52.0-2.8-2.22.2-2.12.3-2.51.22.2-2.22.5-0.51.51.2
Fe content in liver0.50.62.6-0.40.4-0.10.0-0.5-0.7-0.10.7-0.7-1.4-0.50.2-1.2-0.60.6-0.31.61.10.6
K content in liver0.20.21.2-0.50.30.5-0.50.30.5-0.1-0.30.30.70.4-0.21.10.3-0.40.3-0.6-0.5-0.4
Mg content in liver2.02.16.10.3-0.60.7-0.41.21.5-0.2-1.41.42.11.3-0.72.41.4-1.51.1-2.5-2.2-1.3
Mn content in liver2.12.411.32.0-2.2-0.60.90.40.91.0-0.70.73.40.50.11.70.8-0.80.1-2.2-3.0-1.8
Na content in liver0.10.10.4-0.50.50.4-0.3-0.1-0.10.00.3-0.30.1-0.20.20.6-0.30.1-0.10.30.3-0.2
Rb content in liver0.81.01.8-0.70.70.8-1.11.11.3-0.7-1.21.2-0.21.2-1.11.01.2-1.21.1-1.0-0.01.1
Se content in liver1.72.08.01.6-1.8-0.10.80.40.60.6-0.60.62.80.50.11.90.7-0.80.5-2.5-2.4-2.3
Sr content in liver1.11.02.21.2-1.4-1.21.0-0.8-0.61.20.8-0.81.3-0.91.1-0.3-0.80.8-1.10.4-1.5-0.1
Zn content in liver0.30.33.00.1-0.4-0.20.10.00.10.40.0-0.01.0-0.00.40.3-0.0-0.0-0.2-0.4-1.7-0.8
Bone: minimum diameter1.93.68.82.9-2.7-2.22.2-1.5-1.12.31.2-1.23.0-1.41.9-0.1-1.21.2-1.8-1.3-2.8-1.5
Time in familiar zone, hab. session 14.74.47.5-2.62.52.6-2.42.21.8-2.7-2.02.0-1.62.1-2.40.62.0-2.02.1-0.42.61.6
Time in novel zone, hab. session 12.82.85.32.3-2.2-2.32.1-1.6-1.42.11.4-1.41.1-1.61.7-0.8-1.41.4-1.50.3-2.3-1.0
Total zone transitions, hab. session 10.60.81.3-0.90.71.1-1.01.01.1-0.9-1.01.0-0.01.1-0.90.91.0-1.00.9-0.60.4-0.3
Total locomotion distance, hab. session 10.60.81.3-1.10.91.2-1.11.01.1-0.9-0.91.00.21.0-0.91.01.0-1.00.9-0.40.2-0.1
Locomotion velocity, hab. session 10.30.41.1-1.10.90.9-0.80.70.7-0.7-0.60.60.30.7-0.50.70.6-0.60.6-0.10.3-0.4
Time in familiar zone, hab. session 20.50.52.1-0.90.80.8-0.70.70.5-1.0-0.60.6-0.40.7-0.8-0.10.6-0.60.60.41.40.2
Time in novel zone, hab. session 20.40.40.60.7-0.5-0.80.7-0.6-0.70.60.6-0.6-0.8-0.70.6-0.6-0.60.6-0.4-0.0-0.50.1
Total zone transitions, hab. session 20.10.20.7-0.80.50.5-0.70.20.3-0.2-0.10.1-0.20.2-0.10.50.1-0.10.10.70.5-0.0
Total locomotion distance, hab. session 21.21.73.2-1.51.21.6-1.81.41.6-1.2-1.41.4-0.21.4-1.31.51.4-1.31.2-0.40.70.3
Locomotion velocity, hab. session 21.31.83.3-1.51.21.7-1.81.41.7-1.1-1.41.40.01.4-1.31.81.4-1.41.3-0.50.40.0
Novel to familiar place preference ratio0.10.10.6-0.50.50.3-0.20.1-0.1-0.20.1-0.0-0.80.0-0.10.2-0.0-0.00.30.0-0.0-0.2
Novelty place preference0.10.10.4-0.20.20.00.1-0.2-0.40.10.3-0.3-0.6-0.20.20.0-0.30.20.10.1-0.3-0.5
Time in novel zone, NPP test0.10.10.30.10.0-0.20.3-0.4-0.60.20.5-0.5-0.6-0.40.4-0.2-0.40.4-0.10.2-0.3-0.6
Total zone transitions, NPP test1.11.62.6-1.10.91.6-1.61.51.6-1.1-1.41.4-0.51.4-1.41.61.4-1.41.3-0.90.80.4
Total locomotion distance, NPP test1.52.04.0-1.71.51.7-2.01.51.8-1.3-1.41.4-0.81.5-1.51.51.4-1.41.4-0.71.00.9
Locomotion velocity, NPP test2.43.36.3-2.11.82.2-2.52.02.3-1.7-1.91.9-0.91.9-1.92.01.9-1.91.8-1.01.01.1
Intraocular pressure1.21.63.4-0.80.91.3-1.41.41.3-1.4-1.31.3-1.31.3-1.70.71.3-1.21.2-1.01.81.3
Delta distance traveled before/after self-admin1.11.22.70.9-0.7-1.11.5-1.2-1.30.71.1-1.2-0.2-1.21.1-1.7-1.21.2-0.91.5-0.2-0.2
Delta ambulatory time before/after self-admin0.60.71.71.0-1.0-0.81.3-0.9-0.90.70.6-0.70.3-0.80.8-1.0-0.80.8-0.61.1-0.6-0.6
Parametrial fat weight1.52.95.50.6-0.4-1.50.8-1.9-2.01.42.3-2.2-0.9-2.11.6-1.5-2.22.1-2.02.31.60.4
Pavlov. Cond. lever latency1.31.77.0-1.21.3-0.4-0.1-0.5-0.9-0.50.7-0.7-2.6-0.5-0.0-2.7-0.70.8-0.42.02.01.7
Pavlov. Cond. magazine entry latency0.81.13.41.3-1.40.30.40.70.80.1-0.70.81.80.7-0.31.70.8-0.90.6-1.8-1.1-1.1
Pavlov. Cond. change in total contacts1.31.44.31.7-1.6-0.71.3-0.9-0.81.30.8-0.82.1-0.91.20.8-0.80.7-1.0-0.4-1.0-1.9
Pavlov. Cond. index score1.41.87.21.4-1.50.40.20.71.00.4-0.80.92.70.6-0.12.50.9-1.00.5-2.3-1.8-1.5
Pavlov. Cond. latency score1.31.77.61.5-1.60.20.40.30.70.7-0.50.52.80.30.22.50.5-0.60.2-2.1-1.9-1.8
Pavlov. Cond. lever contacts1.21.57.61.4-1.5-0.00.40.00.51.0-0.20.22.8-0.00.52.30.2-0.3-0.2-1.6-1.9-1.6
Pavlov. Cond. magazine entry number1.01.23.8-0.70.8-0.60.0-1.2-1.20.41.2-1.3-1.7-1.10.7-1.5-1.31.4-0.91.90.90.8
Pavlov. Cond. intertrial magazine entries1.51.85.0-1.92.01.1-1.51.00.8-1.5-0.90.8-2.21.0-1.3-0.50.8-0.81.0-0.11.72.2
Pavlov. Cond. lever-magazine prob. diff.1.41.76.51.3-1.40.50.10.81.10.3-0.91.02.60.7-0.22.51.0-1.10.6-2.3-1.6-1.4
Pavlov. Cond. response bias1.21.55.21.2-1.20.40.10.91.10.0-1.01.12.30.9-0.42.01.1-1.20.7-2.2-1.3-0.9
Pavlov. Cond. lever latency0.30.40.80.5-0.6-0.70.5-0.7-0.50.90.7-0.70.2-0.60.80.0-0.60.6-0.60.4-0.90.0
Pavlov. Cond. magazine entry latency0.60.71.60.8-0.8-0.60.7-0.9-0.91.00.9-0.90.8-1.01.00.1-0.90.9-0.90.8-0.6-1.3
Pavlov. Cond. change in total contacts0.10.20.8-0.10.4-0.10.3-0.4-0.6-0.10.3-0.3-0.4-0.40.2-0.7-0.50.4-0.30.70.9-0.5
Pavlov. Cond. index score0.00.00.30.10.00.10.1-0.1-0.2-0.10.0-0.00.2-0.10.0-0.1-0.10.1-0.10.30.4-0.5
Pavlov. Cond. latency score0.10.10.30.10.0-0.10.3-0.3-0.40.00.2-0.20.2-0.30.2-0.3-0.30.3-0.30.50.4-0.5
Pavlov. Cond. lever contacts0.40.52.3-0.81.00.8-0.60.50.3-1.0-0.50.5-1.20.4-0.7-0.40.4-0.40.60.31.50.6
Pavlov. Cond. magazine entry number0.20.30.9-0.30.20.2-0.20.60.6-0.5-0.60.6-0.00.7-0.6-0.00.7-0.70.6-0.9-0.20.6
Pavlov. Cond. intertrial magazine entries0.91.24.00.6-0.80.5-0.11.01.1-0.3-1.21.21.41.1-0.81.31.2-1.20.9-2.0-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.10.00.10.1-0.1-0.2-0.10.0-0.00.1-0.20.0-0.1-0.10.1-0.10.30.3-0.5
Pavlov. Cond. response bias0.20.21.1-0.40.50.7-0.50.40.2-0.7-0.40.4-0.60.3-0.50.20.3-0.30.50.21.00.0
Time in closed arm before self-admin0.00.00.4-0.20.10.10.00.10.1-0.0-0.00.10.10.1-0.1-0.10.2-0.10.0-0.0-0.60.2
Time in closed arm after self-admin0.40.40.8-0.30.3-0.50.3-0.8-0.80.50.8-0.9-0.5-0.70.8-0.7-0.80.8-0.70.80.2-0.2
Time in open arm before self-admin0.20.20.60.6-0.70.30.10.40.3-0.1-0.50.4-0.00.3-0.30.70.2-0.40.5-0.8-0.2-0.7
Time in open arm after self-admin0.40.51.00.4-0.30.6-0.00.90.7-0.7-0.91.00.20.8-0.90.30.9-0.90.8-0.90.2-0.0
Bone: periosteal estimation3.77.712.43.5-3.1-3.43.4-2.9-2.73.32.7-2.72.4-2.83.1-1.8-2.62.7-3.00.4-2.7-1.3
Bone: periosteal perimeter2.13.46.42.5-2.4-2.12.2-1.8-1.52.31.6-1.62.4-1.72.1-0.3-1.51.5-1.9-0.3-2.3-1.5
Bone: post-yield work0.40.62.71.6-1.6-0.90.9-0.2-0.00.90.1-0.11.0-0.20.40.2-0.00.0-0.4-1.1-1.1-0.1
Progressive ratio test 1 active lever presses0.20.20.3-0.50.40.3-0.30.50.4-0.4-0.40.50.50.6-0.40.20.5-0.50.5-0.4-0.2-0.4
Progressive ratio test 1 breakpoint0.20.20.4-0.60.40.2-0.20.50.4-0.4-0.40.50.70.6-0.40.10.5-0.50.4-0.4-0.2-0.4
Progressive ratio test 1 inactive lever presses0.20.21.4-1.01.20.3-0.60.20.2-0.6-0.10.2-0.30.3-0.3-0.30.2-0.20.20.00.60.8
Progressive ratio test 2 active lever presses0.80.91.4-1.01.11.2-1.11.10.9-1.1-0.90.9-0.41.0-1.00.70.9-1.01.1-0.80.70.4
Progressive ratio test 2 breakpoint1.41.52.5-1.41.41.6-1.51.41.2-1.5-1.21.2-0.71.3-1.30.91.2-1.31.4-1.01.00.7
Progressive ratio test 2 inactive lever presses0.20.30.60.6-0.4-0.50.5-0.5-0.60.60.8-0.60.0-0.70.7-0.1-0.60.5-0.50.1-0.2-0.3
Incentive Sensitization - Responses0.90.91.8-0.90.91.3-1.11.00.9-1.1-0.90.9-0.50.9-1.00.90.9-0.91.1-0.70.80.3
Incentive Sensitization - Breakpoint1.01.02.2-0.90.91.5-1.21.11.1-1.2-1.01.0-0.61.0-1.11.01.0-1.01.2-0.80.90.5
Sum of active levers in priming session hrs 5-60.30.30.6-0.50.40.3-0.30.60.7-0.5-0.70.60.50.7-0.50.20.7-0.60.8-0.5-0.6-0.7
Progressive ratio3.84.47.21.3-0.9-2.21.9-2.3-2.71.62.7-2.7-0.7-2.52.1-2.7-2.62.5-2.32.60.60.2
Food seeking constrained by brief footshock0.00.00.1-0.30.00.2-0.00.2-0.1-0.3-0.20.1-0.10.1-0.2-0.30.1-0.20.10.20.1-0.0
Seeking ratio, punishment vs. effort3.23.96.8-1.40.82.0-1.62.32.4-1.6-2.62.60.82.4-2.02.12.5-2.42.2-2.3-0.6-0.3
Retroperitoneal fat weight0.31.02.00.6-0.4-1.20.8-1.1-1.10.81.2-1.3-0.4-1.11.1-1.4-1.21.2-1.21.40.40.1
Reaction time number correct0.40.62.3-1.11.20.1-0.30.0-0.2-0.60.1-0.0-1.30.0-0.3-1.5-0.10.1-0.11.11.31.1
Reaction time mean minus median0.91.26.12.4-2.5-0.30.6-0.10.20.90.1-0.11.1-0.30.31.9-0.1-0.1-0.1-1.5-0.5-1.5
Reaction time mean minus median AUC0.70.93.71.7-1.90.00.20.20.50.6-0.20.21.30.0-0.01.90.2-0.30.1-1.3-0.4-1.4
Reaction time num false alarms0.50.61.10.7-0.6-0.60.7-1.0-0.81.00.8-0.70.9-0.91.00.3-0.90.9-0.70.2-0.5-1.0
Reaction time num false alarms AUC0.81.12.20.9-0.8-0.91.1-1.3-1.11.21.0-1.01.3-1.11.3-0.0-1.11.1-0.90.4-0.8-1.5
Reaction time trials correct on left0.40.62.3-1.11.20.1-0.30.0-0.2-0.60.1-0.0-1.30.0-0.3-1.5-0.10.1-0.11.11.31.1
Reaction time trials on left0.40.52.3-1.01.10.1-0.2-0.0-0.3-0.50.2-0.1-1.2-0.0-0.2-1.5-0.10.2-0.11.11.21.0
Reaction time mean1.01.44.82.0-2.0-0.20.20.30.90.8-0.50.51.70.20.02.20.4-0.50.2-2.0-1.6-1.1
Reaction time mean AUC0.91.34.52.0-2.1-0.20.20.30.80.8-0.50.41.60.10.02.10.3-0.50.2-1.9-1.3-1.2
Median of all reaction times0.71.03.11.4-1.5-0.20.10.30.90.7-0.60.51.50.2-0.01.80.4-0.50.2-1.7-1.7-0.7
Reaction time omissions0.70.93.41.7-1.7-0.30.40.10.40.7-0.40.21.8-0.00.01.70.3-0.3-0.1-1.4-0.9-1.3
Reaction time false alarm rate1.01.44.31.4-1.4-0.91.2-1.1-0.81.40.7-0.72.1-0.91.20.8-0.90.9-0.8-0.3-1.6-2.1
Reaction time premature initiation rate1.11.42.60.5-0.4-1.21.0-1.4-1.31.31.6-1.60.3-1.41.6-1.1-1.51.4-1.41.2-0.70.2
Reaction time premature initiations1.21.73.8-0.00.2-1.20.9-1.5-1.51.01.7-1.7-0.3-1.51.5-1.9-1.61.5-1.51.9-0.00.7
Std. dev. reaction times1.31.87.22.7-2.7-0.71.0-0.30.11.30.1-0.11.9-0.40.61.8-0.20.0-0.3-1.5-1.5-2.1
Reaction time trials completed0.40.52.3-1.01.10.1-0.2-0.0-0.3-0.50.2-0.1-1.2-0.0-0.2-1.5-0.10.2-0.11.11.21.0
Reaction time trials AUC0.40.52.0-1.01.20.1-0.30.0-0.2-0.60.1-0.0-1.20.0-0.3-1.4-0.10.1-0.11.01.21.0
Run reversals in cocaine runway, females0.40.42.0-0.91.10.3-0.60.1-0.1-0.60.1-0.1-1.10.0-0.2-0.6-0.30.20.10.61.40.9
Run reversals in cocaine runway, males1.31.35.82.4-2.1-0.91.2-0.9-0.91.41.0-0.80.5-1.11.00.6-1.00.9-0.7-0.2-0.9-0.8
Latency to leave start box in cocaine runway0.30.33.1-0.0-0.10.10.0-0.4-0.10.60.2-0.11.0-0.30.40.7-0.20.3-0.30.0-0.8-1.8
Latency to leave start box in cocaine runway, F0.40.42.0-0.20.10.6-0.50.40.6-0.1-0.60.61.00.4-0.41.20.6-0.50.3-0.7-0.5-1.4
Latency to leave start box in cocaine runway, M0.90.91.7-0.10.0-0.50.5-1.2-1.00.91.3-1.2-0.2-1.21.2-0.4-1.31.3-1.11.2-0.1-0.7
Std. dev. time between licks in bursts1.82.18.32.1-2.2-1.41.6-0.7-0.31.60.3-0.32.9-0.50.90.9-0.20.3-0.7-1.3-2.6-1.9
Total sessions with >9 infusions0.10.11.10.00.1-0.30.1-0.1-0.10.20.1-0.31.0-0.10.2-0.0-0.20.1-0.2-0.20.1-0.3
Short access day 1 total inactive lever presses0.91.03.81.5-1.6-1.01.0-0.5-0.11.30.4-0.31.9-0.50.70.7-0.30.3-0.6-0.9-1.7-0.5
Short access day 10 total inactive lever presses0.10.20.60.7-0.8-0.20.3-0.20.10.50.1-0.00.4-0.20.20.6-0.10.1-0.2-0.3-0.7-0.1
Short access day 1 total infusions0.30.32.3-0.20.20.1-0.10.60.6-0.3-0.70.61.50.6-0.40.30.6-0.60.5-0.7-0.5-0.5
Short access day 10 total infusions0.10.10.7-0.00.1-0.30.2-0.3-0.30.20.2-0.40.9-0.20.4-0.2-0.30.3-0.20.0-0.3-0.5
Short access total infusions0.20.21.7-0.00.1-0.40.4-0.2-0.30.30.2-0.31.3-0.20.4-0.3-0.20.2-0.3-0.1-0.5-0.8
Short access day 1 locomotion2.62.74.8-1.10.91.5-1.41.92.1-1.4-2.21.91.02.0-1.71.72.1-2.01.9-2.1-0.00.3
Short access day 10 total locomotion1.11.35.91.6-1.7-1.51.6-0.6-0.31.20.2-0.22.4-0.30.7-0.4-0.20.4-0.6-0.5-1.8-1.0
Short access total locomotion0.30.33.10.4-0.4-0.60.50.20.30.3-0.40.31.80.40.0-0.10.4-0.20.1-0.8-0.8-0.3
One hour access (0.3 mA shock)0.80.92.9-0.70.61.3-1.21.01.2-0.8-0.90.90.10.9-0.91.71.0-1.01.0-1.10.2-0.3
Compulsive drug intake2.52.53.9-0.90.51.5-1.21.82.0-1.1-1.92.01.01.9-1.52.02.0-1.91.8-1.9-1.4-0.8
One hour access (shock baseline)0.40.50.90.9-0.6-0.50.4-0.7-0.70.50.9-0.9-0.6-0.90.6-0.4-0.80.8-0.70.51.00.6
Social response proportion0.60.62.01.2-1.2-1.21.2-0.4-0.20.90.3-0.41.4-0.40.7-0.6-0.30.3-0.60.1-1.1-0.6
Social responses0.50.61.60.6-0.7-1.01.1-0.7-0.50.70.4-0.51.3-0.50.8-0.9-0.50.5-0.70.6-0.8-1.0
Social time1.41.87.52.0-2.4-0.91.0-0.6-0.11.60.4-0.42.7-0.61.01.6-0.50.4-0.7-0.9-1.8-1.8
Soleus weight2.05.819.63.5-3.7-2.52.6-1.5-0.83.00.9-0.94.1-1.31.90.9-0.80.9-1.6-1.8-4.4-2.7
Bone: stiffness0.71.12.10.10.2-0.80.5-1.2-1.30.71.4-1.5-0.6-1.31.2-1.2-1.41.4-1.31.20.50.4
Tibialis anterior weight0.20.62.5-1.51.60.6-0.80.20.0-0.7-0.00.0-1.20.2-0.4-0.50.1-0.10.30.10.91.1
Time to tail flick, vehicle, before self-admin0.20.21.90.2-0.20.5-0.70.30.5-0.1-0.30.2-0.20.2-0.31.40.3-0.50.3-0.50.1-0.4
Time to tail flick, vehicle, after self-admin0.60.62.61.0-0.80.1-0.20.70.90.1-0.90.80.50.6-0.51.30.8-0.90.6-1.6-0.90.5
Time to tail flick, test, before self-admin0.20.20.8-0.70.40.5-0.4-0.0-0.2-0.30.0-0.1-0.9-0.1-0.10.2-0.2-0.00.10.60.5-0.5
Time to tail flick, test, after self-admin1.01.02.60.3-0.11.3-0.91.11.0-0.8-1.00.8-0.80.8-1.01.60.9-1.11.2-1.60.80.6
Delta time to tail flick, vehicle, before/after SA0.50.50.9-0.20.20.7-0.50.80.7-0.6-0.90.9-0.20.8-0.70.50.9-0.80.9-0.90.10.9
Delta time to tail flick, test, before/after SA1.21.02.2-0.30.61.1-1.11.11.2-1.0-1.00.9-0.81.1-1.10.81.1-1.01.0-1.31.01.5
Tibia length3.39.416.54.1-3.7-3.93.7-3.2-2.73.72.9-2.92.7-3.13.4-1.9-2.92.9-3.41.2-2.6-1.8
Ambulatory time before self-admin0.10.10.90.4-0.2-0.2-0.1-0.00.00.20.30.0-0.3-0.1-0.10.40.00.0-0.1-0.40.40.9
Ambulatory time after self-admin0.40.52.21.5-1.1-1.01.0-0.5-0.40.70.4-0.30.2-0.60.5-0.7-0.40.5-0.50.3-0.50.6
Bone: tissue strength2.82.75.40.6-0.5-1.31.0-2.1-2.01.62.2-2.2-0.5-2.11.8-1.0-2.22.2-1.92.30.7-0.4
Total heroin consumption0.00.00.40.10.1-0.0-0.10.10.1-0.10.00.3-0.50.1-0.30.10.2-0.10.2-0.6-0.00.1
Bone: trabecular number2.43.87.4-2.32.32.5-2.72.01.9-2.2-1.71.7-2.01.8-2.01.71.7-1.82.0-1.31.21.5
Bone: trabecular spacing4.55.88.42.4-2.3-2.82.9-2.7-2.62.72.5-2.51.7-2.62.7-1.9-2.52.6-2.72.2-1.1-1.6
Bone: trabecular thickness1.72.13.8-1.61.61.8-2.01.51.5-1.6-1.31.3-1.51.4-1.41.11.3-1.31.4-1.00.51.7
Bone: trabecular tissue density1.52.13.80.8-0.8-1.31.5-1.7-1.91.31.7-1.70.2-1.71.8-1.1-1.81.8-1.51.7-0.9-0.7
Water consumed over 24 hours0.10.10.60.4-0.5-0.30.3-0.2-0.00.40.0-0.00.7-0.10.20.4-0.00.1-0.1-0.3-0.8-0.5
Number of responses in last shaping day0.80.93.90.7-0.7-1.01.2-0.7-0.61.00.4-0.52.0-0.50.9-0.2-0.40.6-0.5-0.3-1.9-1.3