Ube2n

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Ube2n 0.06 0.04 6.7e-03 0.01 0 -0 0 2.9e-02 2.5e-01 4.2e-01 1.6e-01
2 IL gene expression Ube2n 0.29 0.11 9.2e-04 -0.01 0.09 0.01 -0.01 5.8e-01 3.3e-03 2.3e-01 4.9e-01
3 OFC mRNA stability Ube2n 0.33 0.12 2.6e-04 0.12 0.12 0.12 0.09 1.1e-03 8.5e-04 8.1e-04 3.2e-03
4 BLA gene expression Ube2n 0.18 0.07 6.5e-07 0.13 0.12 0.05 0.12 1.9e-07 5.4e-07 1.2e-03 6.9e-07
5 Liver gene expression Ube2n 0.06 0.03 2.0e-05 0 0.03 0.01 0.01 1.3e-01 4.9e-04 9.9e-03 7.0e-02
6 LHb gene expression Ube2n 0.25 0.11 7.8e-04 0.01 0.08 0.04 0.04 1.5e-01 7.2e-03 3.5e-02 4.4e-02
7 Brain gene expression Ube2n 0.11 0.05 2.2e-07 0.08 0.06 0.07 0.08 3.8e-08 2.4e-06 2.6e-07 3.7e-08
8 NAcc gene expression Ube2n 0.07 0.03 3.7e-05 0.05 0.04 0.04 0.04 2.5e-06 3.9e-05 5.5e-05 9.8e-06
9 PL gene expression Ube2n 0.14 0.04 2.8e-16 0.17 0.14 0.17 0.17 4.5e-18 6.0e-15 5.8e-18 7.2e-18
10 Adipose mRNA stability Ube2n 0.14 0.06 2.9e-07 0.04 0.06 0.06 0.04 7.5e-05 8.7e-07 8.4e-07 1.8e-05
11 BLA mRNA stability Ube2n 0.08 0.05 6.2e-03 -0 0.02 0.03 0.03 5.5e-01 2.8e-02 1.2e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.52.1-0.2-0.1-0.80.71.4-0.7-0.00.20.10.1-1.3
Area under the delay curve1.11.15.50.30.4-1.60.82.3-0.4-0.60.80.91.20.0
BMI with tail1.03.310.32.63.2-1.1-0.1-0.52.6-0.5-0.1-0.91.72.7
BMI without tail1.42.813.43.73.1-0.10.5-1.51.8-0.30.1-0.80.90.6
Body weight2.610.765.68.16.00.70.1-2.42.8-0.0-0.3-0.80.40.6
Weight adjusted by age1.31.42.8-0.11.3-0.7-1.7-0.21.61.5-1.5-1.6-0.90.5
Bone surface0.30.61.60.61.1-0.9-0.51.30.50.9-0.9-0.5-0.1-0.6
Bone volume0.20.41.60.50.8-0.9-0.01.30.20.3-0.1-0.30.1-0.6
Breakpoint value in progressive ratio session1.21.32.4-1.40.1-0.6-1.31.41.01.1-1.1-1.3-1.50.7
Number of licking bursts0.50.61.21.01.1-1.10.21.10.6-0.20.1-0.21.00.8
Context. condit. distance diff. score0.40.51.20.3-0.20.71.1-0.5-0.7-1.01.10.70.3-0.8
Locomotion velocity, session 10.70.71.8-1.2-0.4-0.7-1.30.70.50.9-0.9-0.9-0.70.6
Locomotion distance, session 10.50.72.0-0.10.3-1.2-1.40.90.60.9-0.8-0.4-0.30.8
Locomotion velocity, session 20.70.92.7-0.6-1.21.2-0.4-0.7-1.00.2-0.10.3-1.4-1.6
Locomotion distance, session 20.91.33.50.71.4-1.4-1.91.51.11.1-0.9-0.7-0.90.1
Locomotion velocity, session 30.50.62.6-0.8-0.70.50.1-0.1-0.60.10.10.0-1.6-1.6
Locomotion distance, session 30.20.20.40.50.6-0.50.40.40.1-0.40.60.40.50.1
Stereotopy head waving bouts, day 31.92.26.1-1.2-0.0-0.3-1.90.00.62.1-1.8-1.7-2.5-1.6
Stereotopy head waving duration, day 31.01.24.4-1.0-0.50.4-0.9-0.70.11.3-1.2-1.1-2.1-1.2
Locomotion velocity, session 70.70.82.3-0.10.8-0.8-0.71.30.70.9-0.7-0.8-1.5-0.7
Locomotion distance, session 70.30.42.5-0.4-0.1-0.5-0.21.6-0.40.10.20.5-0.5-0.7
Stereotopy head waving bouts, day 70.10.10.3-0.3-0.4-0.00.1-0.5-0.30.3-0.1-0.2-0.5-0.4
Stereotopy head waving duration, day 70.10.20.4-0.3-0.5-0.10.6-0.5-0.4-0.20.30.30.50.4
Locomotion velocity, session 80.81.04.6-0.2-0.82.0-0.1-2.1-0.4-0.40.30.1-1.1-0.5
Locomotion distance, session 80.91.24.31.62.1-1.1-1.00.91.10.8-0.5-0.7-0.9-0.7
Degree of sensitization distance0.40.41.2-0.8-0.50.5-0.80.6-0.10.5-0.6-0.1-1.1-0.8
Degree of sensitization stereotypy0.80.91.8-0.6-1.30.61.2-0.5-1.3-1.11.11.10.8-0.0
Conditioned locomotion0.40.52.4-0.1-0.60.60.30.9-0.9-0.30.40.5-0.6-1.5
Cocaine response after cond. corrected0.30.41.30.80.01.10.7-0.5-0.3-0.90.60.30.4-0.3
Cocaine response after cond. not corrected0.20.20.90.90.30.70.5-0.2-0.1-0.70.40.20.4-0.1
Cocaine response before conditioning0.20.30.8-0.00.3-0.6-0.70.10.60.7-0.8-0.3-0.00.9
Saline control response0.20.31.31.20.50.3-0.2-0.60.20.5-0.5-0.3-0.40.0
Bone: connectivity density0.61.02.4-0.5-0.30.1-1.00.6-0.21.4-1.4-0.9-1.3-1.6
Bone: cortical apparent density0.20.30.50.70.0-0.00.20.7-0.5-0.50.70.5-0.3-0.7
Bone: cortical area0.91.32.71.61.3-1.51.01.60.0-0.60.80.71.60.2
Bone: cortical porosity0.50.51.7-0.0-0.61.30.2-1.2-0.50.10.00.2-1.0-0.8
Bone: cortical porosity0.20.20.90.30.30.40.0-0.50.20.4-0.3-0.2-1.0-0.5
Bone: cortical thickness0.50.91.41.10.2-0.61.21.0-0.8-0.71.11.21.1-0.4
Bone: cortical thickness0.40.41.0-0.4-0.80.21.00.4-0.8-0.80.90.80.4-0.2
Bone: cortical tissue density0.20.30.70.7-0.00.10.20.6-0.5-0.50.70.5-0.5-0.8
Condit. Reinf. active minus inactive responses1.31.53.4-1.50.2-1.8-0.91.21.11.3-1.3-1.1-0.11.7
Condit. Reinf. active-inactive response ratio1.21.33.8-1.40.5-1.9-0.21.41.10.7-0.8-1.00.51.7
Condit. Reinf. active responses1.21.53.5-1.9-0.1-1.6-0.90.91.01.2-1.2-1.1-0.11.8
Condit. Reinf. inactive responses0.30.31.5-1.2-0.90.2-0.4-0.4-0.10.2-0.2-0.0-0.20.7
Incentive salience index mean2.73.37.6-0.71.3-2.8-1.71.71.92.2-2.0-1.9-0.42.0
Condit. Reinf. lever presses2.02.76.00.11.6-2.4-1.91.51.72.1-1.8-1.7-0.61.3
Condit. Reinf. active minus inactive responses0.50.61.9-1.2-0.3-0.6-0.8-0.20.70.8-0.8-0.5-0.71.4
Condit. Reinf. active-inactive response ratio0.40.41.7-0.5-0.6-0.00.5-1.0-0.1-0.40.50.40.51.3
Condit. Reinf. active responses0.40.61.6-1.1-0.3-0.3-1.0-0.10.70.7-0.8-0.3-0.51.3
Condit. Reinf. inactive responses0.40.51.5-1.2-0.60.5-1.20.40.30.4-0.7-0.0-0.70.2
Condit. Reinf. lever presses1.11.53.1-0.40.30.0-1.8-1.41.41.3-1.3-1.3-1.41.3
Condit. Reinf. lever reinforcers received0.30.41.6-1.0-0.3-0.4-0.80.20.60.4-0.5-0.0-0.31.3
Conditioned reinforcement - actives1.91.93.51.21.6-0.5-1.80.11.41.9-1.8-1.5-1.40.5
Conditioned reinforcement - inactives2.32.55.31.31.8-0.6-1.81.21.12.2-1.9-1.6-2.3-1.0
Conditioned locomotion0.80.92.51.61.3-0.3-0.80.50.41.0-0.8-0.5-1.3-1.0
Patch foraging indifference point 0 sec0.61.02.00.4-0.60.31.10.0-1.3-1.21.41.21.1-1.1
Patch foraging indifference point AUC0.20.30.80.50.5-0.8-0.30.10.00.8-0.4-0.3-0.2-0.9
Delay disc. indifference point, 0s delay0.50.50.9-0.40.6-0.8-0.90.90.71.0-0.8-0.8-0.70.5
Delay disc. indifference point, 16s delay1.61.66.80.80.5-1.41.12.6-0.5-1.01.11.31.5-0.4
Delay disc. indifference point, 2s delay0.30.40.90.30.7-0.8-0.60.60.60.6-0.5-0.6-0.11.0
Delay disc. indifference point, 24s delay1.11.12.10.8-0.20.01.21.2-1.1-1.11.21.40.6-1.4
Delay disc. indifference point, 4s delay0.30.31.00.2-0.1-0.20.60.2-0.4-0.60.60.71.00.8
Delay disc. indifference point, 8s delay1.31.42.5-0.1-0.5-0.71.41.6-1.1-1.31.41.51.6-0.1
Indifference point function ln k0.30.41.2-0.1-0.40.91.0-0.1-0.4-1.10.70.90.60.0
Indifference point function log k0.30.41.2-0.1-0.40.91.0-0.1-0.4-1.10.70.90.60.0
Patch foraging total patch changes 0 sec0.50.91.60.4-0.60.51.00.0-1.3-1.11.31.20.9-1.1
Patch foraging total patch changes 12 sec0.50.72.31.21.0-1.5-0.4-0.10.50.7-0.3-0.60.90.5
Patch foraging total patch changes 18 sec0.50.61.91.40.1-0.20.8-0.4-0.8-0.61.10.51.1-0.6
Patch foraging total patch changes 24 sec0.70.82.51.60.20.20.9-1.1-0.6-0.81.00.81.20.1
Patch foraging total patch changes 6 sec0.60.93.80.4-0.60.21.0-0.8-0.8-1.01.11.01.90.3
Patch foraging time to switch 0 sec0.10.10.40.2-0.1-0.2-0.6-0.00.10.3-0.3-0.2-0.40.2
Patch foraging water rate 0 sec1.11.76.61.82.6-1.6-0.11.01.60.5-0.4-0.81.10.7
Patch foraging water rate 12 sec0.50.85.02.21.5-0.00.1-0.50.60.0-0.1-0.11.1-0.1
Patch foraging water rate 18 sec0.60.82.30.21.30.0-0.7-0.41.50.9-1.1-1.2-0.40.6
Patch foraging water rate 24 sec1.21.67.82.22.8-1.1-0.20.51.70.4-0.5-0.80.50.4
Patch foraging water rate 6 sec3.34.916.33.34.0-1.1-1.6-0.33.11.8-2.0-2.1-0.40.9
Seeking ratio, delayed vs. immediate footshock0.50.62.4-0.30.4-1.0-0.31.10.10.8-0.4-0.4-0.7-1.6
Distance traveled before self-admin1.41.52.80.11.1-0.7-1.70.01.61.6-1.6-1.6-1.01.1
Distance traveled after self-admin0.70.75.00.51.0-1.30.12.20.30.10.10.1-0.3-0.4
Extensor digitorum longus weight0.10.20.80.90.70.6-0.1-0.50.40.1-0.1-0.1-0.2-0.4
Bone: elastic displacement1.31.57.7-2.8-2.11.1-0.0-1.5-0.4-0.1-0.10.2-0.00.8
Bone: elastic work2.02.66.6-2.2-2.61.31.6-0.7-1.9-1.61.61.70.7-0.3
Bone: endosteal estimation0.40.82.50.21.2-1.40.51.60.6-0.50.40.11.2-0.3
Bone: endosteal perimeter1.02.16.82.02.6-2.00.51.71.3-0.50.3-0.31.80.5
Epididymis fat weight0.61.54.42.11.9-1.00.9-0.41.0-0.40.4-0.01.81.4
Delta time in closed arm before/after self-admin0.40.41.10.50.8-0.7-0.2-0.41.00.2-0.4-0.50.61.1
Delta time in open arm before/after self-admin0.40.42.6-1.6-0.9-0.00.1-0.2-0.5-0.00.20.60.1-0.5
Diff in mean of infusions in LGA sessions0.40.52.4-1.5-1.1-0.20.0-0.1-0.1-0.30.20.20.11.1
Delay discount exponential model param1.01.14.2-0.5-0.21.2-1.0-2.00.60.8-1.0-1.1-1.20.1
Extinction: sum of active levers before priming0.50.51.0-1.0-0.9-0.10.80.3-0.7-0.80.80.80.90.2
Active lever presses in extinction session 62.01.93.8-0.11.6-2.0-1.51.61.81.6-1.4-1.3-0.10.8
Bone: final force2.43.98.31.00.5-1.92.62.9-1.2-2.12.52.02.6-0.7
Bone: final moment2.13.48.60.90.5-1.92.42.9-1.1-1.82.11.82.4-0.6
Food consumed during 24 hour testing period1.11.42.60.9-0.61.61.6-1.6-0.9-1.51.11.01.00.3
Glucose0.00.10.20.20.1-0.40.1-0.00.0-0.10.1-0.00.30.5
Heart weight0.71.07.7-0.10.9-1.30.32.80.30.10.10.2-0.6-0.5
Delay discount hyperbolic model param0.60.62.9-0.5-0.41.1-0.6-1.70.30.5-0.6-0.7-0.9-0.2
Intermittent access intake day 1-15 change2.32.33.71.71.8-0.4-1.7-1.31.81.5-1.7-1.60.11.9
Intermittent access intake escalation2.22.24.21.91.8-0.5-1.5-1.01.71.4-1.5-1.50.42.0
Intermittent access intake escalation 21.01.02.11.01.4-0.7-1.1-0.21.21.1-1.1-1.10.40.8
Intermitt. access day 1 inactive lever presses1.11.23.4-1.8-1.80.50.90.3-1.3-0.70.90.8-0.9-0.8
Intermitt. access day 15 inactive lever presses0.50.51.8-1.3-1.00.70.20.3-0.5-0.10.10.1-1.4-0.3
Intermitt. access escalation Index0.40.31.9-1.4-0.80.1-0.3-0.90.30.1-0.2-0.2-0.30.4
Intermittent access day 1 total infusions0.70.93.82.00.51.5-0.1-1.70.0-0.30.10.40.20.1
Intermittent access day 15 total infusions1.82.19.03.01.90.9-1.3-1.81.10.9-1.1-0.8-0.00.8
Intermittent access terminal intake (last 3 days)1.61.77.82.81.70.9-1.0-1.71.10.6-0.8-0.50.11.1
Intermittent access total infusions1.21.37.72.81.40.8-0.4-1.60.6-0.0-0.20.10.60.8
Intermittent access day 1 locomotion1.01.03.11.50.01.30.6-0.3-1.1-0.70.81.1-0.1-1.8
Intermittent access day 15 total locomotion1.31.46.22.50.41.50.5-0.7-1.1-0.30.40.4-0.9-1.7
Intermittent access total locomotion1.11.25.72.40.51.50.6-1.1-0.8-0.60.60.7-0.2-1.4
Intermittent access standard deviation1.92.07.82.82.3-0.7-1.2-0.31.31.2-1.2-1.00.60.8
Left kidney weight0.41.39.53.11.80.30.2-0.80.5-0.00.10.2-0.0-0.0
Right kidney weight0.41.27.02.61.70.6-0.2-1.20.90.5-0.5-0.2-0.5-0.2
Cocaine induced anxiety2.12.43.9-1.6-2.00.11.81.3-1.9-1.81.81.81.3-0.0
Post-drug Anxiety2.22.46.1-2.1-2.50.71.5-0.0-1.8-1.71.71.71.20.5
Baseline Anxiety0.30.32.50.3-0.30.80.0-1.6-0.0-0.1-0.0-0.0-0.10.2
Tail length2.16.437.26.13.21.80.0-2.40.51.0-0.6-0.6-1.7-3.0
Length with tail2.48.959.47.74.41.90.1-2.50.80.8-0.5-0.2-1.6-2.3
Length without tail0.92.013.53.72.50.5-0.2-0.60.70.3-0.30.0-0.7-0.2
Times rat made contact with spout1.51.77.52.71.4-1.20.81.00.1-0.30.30.32.11.4
Lifetime Intake0.91.05.92.41.30.7-0.4-1.10.6-0.1-0.20.10.70.9
Liver weight, left1.11.83.90.01.8-1.0-1.40.22.01.7-1.7-1.7-0.70.5
Liver weight, right1.22.14.40.61.4-0.2-1.7-0.61.52.1-2.1-1.5-1.9-0.6
Locomotor activity2.03.210.62.93.3-1.8-1.11.52.11.2-1.1-1.3-0.30.7
Locomotor testing distance1.72.88.12.02.8-2.3-0.71.72.10.7-0.8-0.90.81.7
Locomotor testing rearing1.11.75.11.12.3-1.8-1.10.91.80.8-0.7-1.10.11.2
Locomotion in novel chamber0.70.91.80.50.7-1.2-0.81.20.61.2-0.9-0.8-0.9-1.3
Locomotion in novel chamber post-restriction0.40.51.20.60.11.1-0.7-0.90.00.4-0.6-0.7-0.8-0.9
Fecal boli incidents, locomotor time 10.20.21.70.20.00.4-0.00.1-0.40.10.10.0-0.1-1.3
Change in fecal boli incidents, locomotor task1.91.83.0-0.9-1.0-0.61.71.7-1.2-1.71.71.71.10.1
Time >=10cm from walls, locomotor time 10.20.30.8-0.9-0.3-0.20.3-0.60.4-0.40.30.10.50.8
Bouts of movement, locomotor time 10.30.30.9-0.10.5-0.1-0.70.90.40.6-0.6-0.4-0.5-0.6
Total resting periods, locomotor time 10.30.30.7-0.50.20.1-0.70.80.20.7-0.7-0.3-0.7-0.6
Rest time, locomotor task time 10.50.62.3-1.5-0.90.5-0.6-1.0-0.00.6-0.6-0.5-0.7-0.4
Distance moved, locomotor task time 11.41.53.41.01.8-1.8-0.80.41.61.0-0.9-1.20.11.6
Vertical activity count, locomotor time 11.71.84.31.72.1-1.8-0.91.01.70.9-0.9-0.80.21.5
Time >=10cm from walls, locomotor time 20.80.92.5-0.9-1.0-0.50.8-0.6-0.6-0.70.90.61.61.3
Bouts of movement, locomotor time 20.40.41.00.10.90.5-0.8-0.20.90.5-0.8-0.7-1.0-0.3
Total resting periods, locomotor time 20.20.30.7-0.20.70.3-0.6-0.00.80.4-0.6-0.6-0.6-0.1
Rest time, locomotor task time 20.20.21.8-1.3-0.40.0-0.4-0.10.40.2-0.4-0.20.00.5
Distance moved, locomotor task time 20.60.71.70.70.7-0.4-0.8-0.90.90.8-0.8-1.0-0.41.3
Vertical activity count, locomotor time 21.31.55.32.31.9-0.9-0.9-0.51.31.0-0.8-1.0-0.41.0
Light reinforcement 10.10.20.30.50.40.1-0.6-0.30.50.2-0.3-0.6-0.20.6
Light reinforcement 20.40.51.1-0.3-0.81.00.7-0.2-0.9-0.80.70.80.5-1.0
Bone: marrow area0.30.72.10.21.2-1.30.61.50.5-0.50.40.21.3-0.2
Bone: maximum diameter0.91.64.22.02.1-1.50.81.80.7-0.70.60.21.60.3
Bone: maximum force1.01.83.60.40.1-1.11.71.7-0.9-1.51.71.71.9-0.2
Bone: maximum moment0.91.63.60.20.0-1.21.51.9-0.8-1.21.41.51.8-0.0
Mean time between licks in bursts0.50.72.30.21.0-0.3-0.4-0.51.30.8-1.1-0.7-0.31.5
Mean num. licks in bursts0.10.10.20.4-0.40.00.1-0.1-0.50.1-0.00.30.40.2
Cd content in liver0.80.83.30.91.8-0.7-0.51.01.40.3-0.3-0.9-0.50.0
Co content in liver0.60.72.61.61.20.70.1-1.00.70.3-0.4-0.9-0.5-0.1
Cu content in liver0.60.81.71.11.01.1-0.3-1.30.80.2-0.2-0.9-1.1-0.7
Fe content in liver0.91.12.20.70.3-0.51.41.5-0.9-1.11.31.20.6-1.2
K content in liver2.52.47.60.3-0.41.7-1.7-1.70.01.7-1.5-1.3-2.8-1.8
Mg content in liver1.81.95.00.20.40.7-1.8-0.90.91.8-1.9-1.6-2.2-0.8
Mn content in liver0.40.51.10.71.0-0.2-0.4-0.10.90.8-0.8-0.9-0.50.1
Na content in liver1.31.43.30.3-1.51.21.0-0.6-1.8-1.21.21.61.1-0.4
Rb content in liver1.51.86.6-0.4-1.22.60.6-1.2-1.3-0.30.20.3-1.3-2.5
Se content in liver0.00.10.10.30.3-0.3-0.00.20.1-0.20.30.2-0.4-0.0
Sr content in liver0.90.82.3-0.31.1-1.5-0.11.10.90.9-0.4-1.4-0.7-0.0
Zn content in liver0.70.83.30.3-0.61.80.2-1.7-0.4-0.30.20.5-0.9-0.2
Bone: minimum diameter1.73.36.92.62.3-2.11.42.20.4-1.41.51.02.60.7
Time in familiar zone, hab. session 10.10.10.2-0.4-0.40.20.1-0.2-0.1-0.40.30.2-0.3-0.1
Time in novel zone, hab. session 11.91.84.0-0.3-1.10.41.61.0-1.6-1.61.62.01.8-0.3
Total zone transitions, hab. session 15.07.011.61.23.1-3.3-3.42.32.93.2-2.8-2.7-1.80.9
Total locomotion distance, hab. session 16.69.418.70.93.0-2.8-4.31.63.54.1-3.9-3.5-2.51.1
Locomotion velocity, hab. session 110.815.327.31.24.0-3.6-5.21.54.65.2-5.0-4.8-3.31.6
Time in familiar zone, hab. session 20.30.31.3-0.3-0.41.1-0.6-0.70.20.2-0.60.2-0.10.7
Time in novel zone, hab. session 20.40.41.0-0.5-0.0-0.80.71.0-0.3-0.60.80.30.0-0.6
Total zone transitions, hab. session 21.82.47.70.41.5-2.8-1.72.61.41.3-1.0-0.9-0.30.9
Total locomotion distance, hab. session 25.67.412.60.22.9-3.1-3.62.13.43.2-3.1-3.1-1.61.7
Locomotion velocity, hab. session 26.38.514.20.23.1-3.4-3.82.13.73.5-3.3-3.4-1.81.6
Novel to familiar place preference ratio1.11.14.8-0.2-1.42.2-0.0-2.0-0.9-0.60.40.4-0.6-0.2
Novelty place preference1.31.35.0-0.6-1.62.20.1-2.0-1.0-0.70.50.5-0.6-0.1
Time in novel zone, NPP test1.31.35.0-0.5-1.72.20.4-1.7-1.2-1.00.70.8-0.3-0.1
Total zone transitions, NPP test2.02.86.50.72.1-2.5-1.82.51.61.6-1.2-1.2-1.3-0.2
Total locomotion distance, NPP test6.69.118.50.73.1-2.4-4.31.53.54.0-3.9-3.4-2.70.8
Locomotion velocity, NPP test6.49.018.50.42.9-2.4-4.31.33.44.1-3.9-3.5-2.90.6
Intraocular pressure0.10.20.7-0.50.1-0.50.2-0.40.5-0.00.0-0.80.40.6
Delta distance traveled before/after self-admin0.60.63.30.50.5-0.90.51.8-0.4-0.40.70.5-0.1-1.2
Delta ambulatory time before/after self-admin1.41.54.6-0.2-0.3-0.71.42.1-1.2-1.31.61.40.7-1.2
Parametrial fat weight0.40.74.3-1.1-0.4-0.90.42.1-0.3-0.50.60.70.4-0.5
Pavlov. Cond. lever latency0.30.41.20.60.21.10.9-0.4-0.2-0.90.60.60.2-0.7
Pavlov. Cond. magazine entry latency0.50.71.9-0.4-0.2-1.4-0.11.10.0-0.10.20.51.41.4
Pavlov. Cond. change in total contacts0.80.83.90.20.1-1.4-0.20.60.2-0.00.10.22.01.6
Pavlov. Cond. index score0.70.93.1-0.50.2-1.8-1.01.10.60.8-0.6-0.50.61.5
Pavlov. Cond. latency score0.70.92.9-0.60.1-1.7-1.00.90.61.0-0.7-0.60.31.4
Pavlov. Cond. lever contacts0.80.92.1-0.00.4-1.4-1.40.50.81.4-1.1-1.1-0.21.0
Pavlov. Cond. magazine entry number0.50.61.80.20.21.20.1-1.40.10.1-0.2-0.5-1.3-1.1
Pavlov. Cond. intertrial magazine entries1.21.43.20.30.3-0.61.81.6-0.5-1.71.61.31.4-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.03.6-0.40.3-1.9-1.01.30.60.8-0.5-0.40.71.5
Pavlov. Cond. response bias0.70.83.40.10.3-1.9-0.71.20.50.5-0.4-0.30.91.4
Pavlov. Cond. lever latency0.20.32.10.40.20.80.10.1-0.3-0.10.0-0.4-0.5-1.5
Pavlov. Cond. magazine entry latency0.50.63.40.70.0-0.40.1-0.90.2-0.20.00.31.31.9
Pavlov. Cond. change in total contacts0.81.13.21.41.7-1.80.10.31.10.2-0.00.10.91.6
Pavlov. Cond. index score0.50.63.10.90.5-1.00.0-0.30.50.0-0.00.31.11.8
Pavlov. Cond. latency score0.40.42.30.70.5-0.9-0.2-0.40.60.2-0.20.10.71.5
Pavlov. Cond. lever contacts0.60.83.90.00.5-1.6-0.20.40.80.3-0.20.21.22.0
Pavlov. Cond. magazine entry number1.01.24.7-1.2-1.21.50.2-0.0-1.1-0.30.40.2-1.2-2.2
Pavlov. Cond. intertrial magazine entries0.40.52.0-0.7-0.41.2-0.6-0.60.20.2-0.4-0.3-1.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.50.62.91.10.6-1.00.1-0.30.40.00.00.31.21.7
Pavlov. Cond. response bias0.81.15.00.60.8-1.7-0.10.40.80.2-0.10.31.52.2
Time in closed arm before self-admin0.10.10.80.40.20.2-0.3-0.00.10.1-0.1-0.0-0.9-0.3
Time in closed arm after self-admin0.20.20.50.40.6-0.3-0.2-0.20.70.1-0.4-0.50.50.7
Time in open arm before self-admin0.00.10.20.20.1-0.40.30.4-0.0-0.10.2-0.10.1-0.2
Time in open arm after self-admin0.20.31.1-1.1-0.7-0.40.30.3-0.5-0.10.40.60.0-0.5
Bone: periosteal estimation0.71.53.91.11.5-1.51.12.00.2-0.90.90.71.7-0.3
Bone: periosteal perimeter0.81.44.41.31.9-1.80.52.10.7-0.50.50.01.1-0.2
Bone: post-yield work1.01.43.10.6-0.70.11.60.6-1.4-1.51.41.81.60.1
Progressive ratio test 1 active lever presses1.71.813.13.61.61.2-0.3-1.30.30.1-0.2-0.10.2-0.4
Progressive ratio test 1 breakpoint1.61.711.63.41.71.0-0.5-1.30.60.3-0.4-0.30.2-0.1
Progressive ratio test 1 inactive lever presses0.40.41.90.2-0.11.3-0.4-0.60.10.4-0.5-0.5-1.4-0.1
Progressive ratio test 2 active lever presses2.22.46.42.52.00.3-1.8-1.01.51.5-1.6-1.6-1.30.6
Progressive ratio test 2 breakpoint2.52.97.82.82.20.0-1.9-1.21.71.6-1.7-1.9-1.01.0
Progressive ratio test 2 inactive lever presses0.50.62.20.50.50.3-0.90.10.31.0-0.9-0.8-1.5-0.5
Incentive Sensitization - Responses2.62.64.82.21.9-0.1-1.8-0.61.51.8-1.8-2.1-2.00.4
Incentive Sensitization - Breakpoint2.32.44.12.01.70.0-1.7-0.71.41.7-1.7-2.0-2.00.3
Sum of active levers in priming session hrs 5-61.71.63.40.41.2-1.2-1.51.41.41.3-1.3-1.4-0.41.8
Progressive ratio0.30.42.4-1.6-1.00.10.20.2-0.5-0.20.40.2-0.5-0.4
Food seeking constrained by brief footshock0.40.52.91.70.40.70.7-0.6-0.4-0.60.70.20.2-0.3
Seeking ratio, punishment vs. effort0.40.53.11.80.70.30.4-0.2-0.1-0.50.50.40.70.0
Retroperitoneal fat weight1.03.39.62.83.1-1.2-1.00.12.41.6-1.5-1.8-1.21.0
Reaction time number correct0.30.41.50.30.8-1.00.01.20.50.5-0.4-0.50.50.2
Reaction time mean minus median0.60.82.1-1.4-1.51.10.3-0.4-0.9-0.10.10.5-1.3-0.7
Reaction time mean minus median AUC0.50.61.8-1.2-1.41.10.1-0.7-0.70.1-0.20.3-1.1-0.2
Reaction time num false alarms1.01.33.4-1.3-1.81.40.5-0.3-1.5-1.11.01.0-0.4-1.1
Reaction time num false alarms AUC0.71.02.6-1.6-1.61.20.2-0.2-1.1-0.80.70.5-0.8-0.9
Reaction time trials correct on left0.30.41.50.30.8-1.00.01.20.50.5-0.4-0.50.50.2
Reaction time trials on left0.30.41.60.20.7-1.00.11.30.40.4-0.3-0.40.50.2
Reaction time mean0.20.20.6-0.20.7-0.5-0.30.60.80.1-0.1-0.4-0.70.2
Reaction time mean AUC0.10.20.80.00.7-0.2-0.30.30.70.1-0.0-0.5-0.90.1
Median of all reaction times0.40.62.20.61.5-0.8-0.40.61.20.1-0.1-0.7-0.40.5
Reaction time omissions2.02.77.7-2.2-2.81.41.60.2-1.8-1.71.31.90.80.5
Reaction time false alarm rate0.91.23.3-1.6-1.81.50.1-0.7-1.2-0.90.70.7-1.0-1.0
Reaction time premature initiation rate2.33.05.70.31.8-2.0-1.90.22.42.3-2.3-2.0-0.51.5
Reaction time premature initiations2.23.25.60.62.0-2.0-1.80.42.42.3-2.3-2.1-0.41.4
Std. dev. reaction times0.50.72.3-1.5-1.30.8-0.00.1-0.60.00.00.3-1.5-0.6
Reaction time trials completed0.30.41.60.20.7-1.00.11.30.40.4-0.3-0.40.50.2
Reaction time trials AUC0.40.51.60.41.0-1.1-0.21.30.70.6-0.5-0.70.40.3
Run reversals in cocaine runway, females2.92.85.50.21.7-0.8-2.3-0.12.02.3-2.3-2.2-1.6-0.3
Run reversals in cocaine runway, males1.11.13.4-0.1-0.7-0.01.3-0.2-1.0-1.31.31.31.90.5
Latency to leave start box in cocaine runway0.20.31.80.40.2-0.50.00.60.3-0.0-0.0-0.10.51.3
Latency to leave start box in cocaine runway, F0.40.52.1-0.60.2-0.9-0.21.10.60.0-0.2-0.30.31.5
Latency to leave start box in cocaine runway, M0.60.63.11.80.50.6-0.2-0.4-0.20.6-0.4-0.2-0.8-1.0
Std. dev. time between licks in bursts0.50.61.9-1.30.1-0.9-0.30.30.90.6-0.7-0.1-0.01.4
Total sessions with >9 infusions0.40.53.01.71.00.5-0.4-0.40.40.1-0.30.10.50.0
Short access day 1 total inactive lever presses0.20.21.00.2-0.2-0.00.31.0-0.5-0.30.30.5-0.1-0.2
Short access day 10 total inactive lever presses1.92.112.3-3.5-2.51.00.3-0.9-0.7-0.30.2-0.1-1.30.7
Short access day 1 total infusions0.91.02.41.61.20.2-1.2-0.11.20.8-1.1-0.9-0.51.1
Short access day 10 total infusions1.01.17.22.71.40.50.4-0.80.2-0.60.50.40.90.2
Short access total infusions0.91.04.72.21.5-0.0-0.6-0.41.00.3-0.5-0.40.81.3
Short access day 1 locomotion0.50.52.21.50.70.6-0.7-0.70.50.5-0.6-0.6-0.20.6
Short access day 10 total locomotion0.30.32.30.40.3-0.10.30.4-0.20.10.10.4-0.7-1.5
Short access total locomotion0.40.42.81.70.80.1-0.10.2-0.00.3-0.20.1-0.3-0.7
One hour access (0.3 mA shock)1.82.17.32.72.3-0.2-1.5-0.51.41.5-1.5-0.9-0.40.6
Compulsive drug intake1.31.33.4-1.8-1.8-0.11.10.8-1.5-0.71.01.20.3-0.6
One hour access (shock baseline)2.42.89.53.12.60.3-1.7-1.21.71.5-1.6-1.1-0.40.9
Social response proportion1.31.43.41.31.9-0.9-1.01.71.21.3-1.1-0.9-1.0-0.6
Social responses3.95.08.40.92.8-1.9-2.41.32.82.9-2.8-2.7-1.80.7
Social time0.60.81.81.21.4-1.2-0.80.70.90.9-0.6-0.80.30.5
Soleus weight0.30.82.80.30.0-0.10.81.1-0.6-0.90.91.31.70.0
Bone: stiffness1.72.710.91.81.4-2.01.43.3-0.5-0.91.31.51.4-1.3
Tibialis anterior weight0.51.64.3-0.0-0.1-0.72.00.8-0.5-1.71.71.42.10.6
Time to tail flick, vehicle, before self-admin1.11.16.12.50.6-0.30.80.8-0.7-0.60.70.91.50.0
Time to tail flick, vehicle, after self-admin0.30.31.9-1.4-0.2-0.80.10.60.20.00.00.10.50.5
Time to tail flick, test, before self-admin0.80.73.00.90.4-0.40.61.2-0.6-0.60.70.80.3-1.7
Time to tail flick, test, after self-admin0.40.50.90.20.8-1.0-0.60.80.70.8-0.8-0.8-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.90.97.2-2.7-0.8-0.1-0.3-0.60.60.2-0.3-0.30.00.9
Delta time to tail flick, test, before/after SA0.40.41.2-0.60.0-0.5-0.5-0.70.60.6-0.6-0.6-0.01.1
Tibia length1.74.929.15.44.4-1.10.4-0.11.8-0.20.3-0.60.10.1
Ambulatory time before self-admin1.21.32.50.10.70.1-1.6-0.91.31.5-1.6-1.5-1.10.5
Ambulatory time after self-admin0.40.52.50.51.0-1.0-0.21.60.40.3-0.1-0.0-0.2-0.4
Bone: tissue strength0.60.53.10.50.7-1.20.21.8-0.20.10.30.30.4-0.6
Total heroin consumption0.70.82.5-0.90.3-1.1-0.91.60.90.7-0.7-0.7-0.41.0
Bone: trabecular number0.20.31.5-0.4-0.2-0.6-0.01.0-0.40.4-0.2-0.5-0.2-1.2
Bone: trabecular spacing0.60.84.6-0.5-0.81.1-0.3-2.10.2-0.1-0.10.0-0.11.5
Bone: trabecular thickness0.30.40.90.4-0.2-0.00.90.6-0.8-0.80.80.60.3-0.8
Bone: trabecular tissue density0.10.10.40.20.1-0.6-0.00.4-0.1-0.20.50.2-0.1-0.1
Water consumed over 24 hours1.31.63.41.8-0.11.41.6-0.4-1.2-1.61.31.41.4-0.2
Number of responses in last shaping day0.40.42.61.60.9-0.5-0.50.20.40.6-0.50.10.4-0.0